|
Name |
Accession |
Description |
Interval |
E-value |
| PLN03210 |
PLN03210 |
Resistant to P. syringae 6; Provisional |
15-1103 |
3.60e-102 |
|
Resistant to P. syringae 6; Provisional
Pssm-ID: 215633 [Multi-domain] Cd Length: 1153 Bit Score: 349.56 E-value: 3.60e-102
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235064 15 HQVFLNFRGDELRNNFVSHLDKALRGKQINVFIDEAVEKGENLDNLFKE-IEKSRIALAIISQKYTESKWCLNEL---VK 90
Cdd:PLN03210 13 YDVFPSFSGEDVRITFLSHFLKELDRKLIIAFKDNEIERSQSLDPELKQaIRDSRIAVVVFSKNYASSSWCLNELleiVR 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235064 91 MKELEGKLVtIPIFYNVEPATVRYQKEAFGAALTKTQENDSDGQMKKWKEALTYVSLLVGFpfNSKSKEKETTLIDKIVD 170
Cdd:PLN03210 93 CKEELGQLV-IPVFYGLDPSHVRKQTGDFGEAFEKTCQNKTEDEKIQWKQALTDVANILGY--HSQNWPNEAKMIEEIAN 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235064 171 AVLQKLSKisseeSTSGSVDQGRGEEveeakaDKISGLNQRLkELEEKvaitgdkrdETRIVEVVGMPGIGKSTLLKAFY 250
Cdd:PLN03210 170 DVLGKLNL-----TPSNDFEDFVGIE------DHIAKMSSLL-HLESE---------EVRMVGIWGSSGIGKTTIARALF 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235064 251 ETWKTRFLSSALLQN--ISELVKA----------MGLgRLTGMLLKELLPDENIDEETYEPYKEKLLKNTVFIVLDGISD 318
Cdd:PLN03210 229 SRLSRQFQSSVFIDRafISKSMEIyssanpddynMKL-HLQRAFLSEILDKKDIKIYHLGAMEERLKHRKVLIFIDDLDD 307
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235064 319 EThIQKLLKDHRKWAKKGSKIVIarraVTRD--LLHEDSmVRYTYFVPLLSHRDGLNHFCHYAFRHfaahQNNKEAFMKE 396
Cdd:PLN03210 308 QD-VLDALAGQTQWFGSGSRIIV----ITKDkhFLRAHG-IDHIYEVCLPSNELALEMFCRSAFKK----NSPPDGFMEL 377
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235064 397 SKEFVRYARGHPLILKLLGEELREKSLSYWEEKLKSLPKSLSQNIrDRVLQVTYDELSQVQKDA-FLDIAC-FRSHDLVY 474
Cdd:PLN03210 378 ASEVALRAGNLPLGLNVLGSYLRGRDKEDWMDMLPRLRNGLDGKI-EKTLRVSYDGLNNKKDKAiFRHIAClFNGEKVND 456
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235064 475 VKSLLDSSGpafSKATVTIDALKDMFMIYISDSRVEMHDLLYTFAMELGPEARDDDGRGRHRIWHHHNQDnkgrlnrLLK 554
Cdd:PLN03210 457 IKLLLANSD---LDVNIGLKNLVDKSLIHVREDIVEMHSLLQEMGKEIVRAQSNEPGEREFLVDAKDICD-------VLE 526
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235064 555 RPGGSTSVRSFFLDMYvmKTD-VTLGTDYLKNMRNLRYLKFYSSHCPQectpKENI--HIPGELELPLEEVRCLHWLNFP 631
Cdd:PLN03210 527 DNTGTKKVLGITLDID--EIDeLHIHENAFKGMRNLLFLKFYTKKWDQ----KKEVrwHLPEGFDYLPPKLRLLRWDKYP 600
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235064 632 KDELPQDFIPKNLVDLKLPYSKIRQIWREEKDAPKLRWVDLNHSSKLENLSGLSQALNLERLNLEGCTALKTLLLGPENM 711
Cdd:PLN03210 601 LRCMPSNFRPENLVKLQMQGSKLEKLWDGVHSLTGLRNIDLRGSKNLKEIPDLSMATNLETLKLSDCSSLVELPSSIQYL 680
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235064 712 ASLVFLNLKGCTGLESLPK-INLRSLKTLILSNCSNLEEFWVISETLYTLYLDGTAIKTLP-----QDMVKLT------- 778
Cdd:PLN03210 681 NKLEDLDMSRCENLEILPTgINLKSLYRLNLSGCSRLKSFPDISTNISWLDLDETAIEEFPsnlrlENLDELIlcemkse 760
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235064 779 ------------------SLVKLYMKDCEMLVKLPEEFDKLKVLQELV---C--------------------SGCKRLSS 817
Cdd:PLN03210 761 klwervqpltplmtmlspSLTRLFLSDIPSLVELPSSIQNLHKLEHLEienCinletlptginleslesldlSGCSRLRT 840
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235064 818 LPDVMKNmqcLQILLLDGTAITKIP----HISSLERLCLSRNEKISCLSNDIRLLSQLKWLDLKYCtklVSIPELPTNlq 893
Cdd:PLN03210 841 FPDISTN---ISDLNLSRTGIEEVPwwieKFSNLSFLDMNGCNNLQRVSLNISKLKHLETVDFSDC---GALTEASWN-- 912
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235064 894 cldaNGCESLTTVANPLATHLPteqihSTFI--FTNCDKLDRTAKegFVPEALF-STCFPGCEVPSWFCHEAVGSVLKLN 970
Cdd:PLN03210 913 ----GSPSEVAMATDNIHSKLP-----STVCinFINCFNLDQEAL--LQQQSIFkQLILSGEEVPSYFTHRTTGASLTNI 981
|
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235064 971 LLPHWNENR-FVGIALCAVVGSLpncQEQTNSCS----VTCTFniaskdskkgdpykisfdrlvgrwnkhgnkLDKKGNK 1045
Cdd:PLN03210 982 PLLHISPCQpFFRFRACAVVDSE---SFFIISVSfdiqVCCRF------------------------------IDRLGNH 1028
|
1130 1140 1150 1160 1170 1180
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 15235064 1046 LKKTESDHVFICYTRCSNSI--KCLQDQHSGTCTPTE-----AFLEFGVTDKESRLEVLKCGLRL 1103
Cdd:PLN03210 1029 FDSPYQPHVFSVTKKGSHLVifDCCFPLNEDNAPLAElnydhVDIQFRLTNKNSQLKLKGCGIRL 1093
|
|
| TIR |
pfam01582 |
TIR domain; The Toll/interleukin-1 receptor (TIR) homology domain is an intracellular ... |
15-179 |
1.46e-40 |
|
TIR domain; The Toll/interleukin-1 receptor (TIR) homology domain is an intracellular signalling domain found in MyD88, interleukin 1 receptor and the Toll receptor. It contains three highly-conserved regions, and mediates protein-protein interactions between the Toll-like receptors (TLRs) and signal-transduction components. TIR-like motifs are also found in plant proteins thought to be involved in resistance to disease. When activated, TIR domains recruit cytoplasmic adaptor proteins MyD88 and TOLLIP (Toll interacting protein). In turn, these associate with various kinases to set off signalling cascades.
Pssm-ID: 396246 [Multi-domain] Cd Length: 165 Bit Score: 147.13 E-value: 1.46e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235064 15 HQVFLNFRGDELRNNFVSHLDKALRGKQINVFIDEA-VEKGENL-DNLFKEIEKSRIALAIISQKYTESKWCLNELVKMK 92
Cdd:pfam01582 1 YDVFLSFRGSDTREWFVSHLLKELKQKGIKLFIDDRdLEPGEAIaPELLSAIEKSRRSVVVLSPNYASSGWCLDELVKIL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235064 93 E--LEGKLVTIPIFYNVEPATVRYQKEAFGAALTKTQENDSDGQMKKWKEALTYVSLLvgfpFNSKSKEKETTLIDKIVD 170
Cdd:pfam01582 81 EcaLDLGQKVIPIFYEVDPSDVRKQTGSFGKAFKKHKKVLTEEKVLKWRGALNEVANI----WHSKSVSDESKFWKKIAY 156
|
....*....
gi 15235064 171 AVLQKLSKI 179
Cdd:pfam01582 157 DISNKLNGT 165
|
|
| TIR |
smart00255 |
Toll - interleukin 1 - resistance; |
14-148 |
7.62e-40 |
|
Toll - interleukin 1 - resistance;
Pssm-ID: 214587 [Multi-domain] Cd Length: 140 Bit Score: 144.00 E-value: 7.62e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235064 14 QHQVFLNFRG-DELRNNFVSHLDKALRGKQINVFIDEAVEKGENLDNLFKEIEKSRIALAIISQKYTESKWCLNELVKMK 92
Cdd:smart00255 1 EYDVFISYSGkEDVRNEFLSHLLEKLRGYGLCVFIDDFEPGGGDLEEIDEAIEKSRIAIVVLSPNYAESEWCLDELVAAL 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235064 93 EL---EGKLVTIPIFYNVEPATVRYQKEAFGAALTKT-QENDSDGQMKKWKEALTYVSLL 148
Cdd:smart00255 81 ENaleEGGLRVIPIFYEVIPSDVRKQPGKFRKVFKKNyLKWPEDEKEQFWKKALYAVPSK 140
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
642-878 |
2.16e-21 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 98.47 E-value: 2.16e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235064 642 KNLVDLKLPYSKIRQIWREEKDAPKLRWVDLNHSSKLENLSGLSQALNLERLNLEGCTALktlllgpENMASLVFLNLKG 721
Cdd:COG4886 50 TLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGNEEL-------SNLTNLESLDLSG 122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235064 722 cTGLESLPKI--NLRSLKTLILSNC--SNLEEFWVISETLYTLYLDGTAIKTLPQDMVKLTSLVKLYMKDCEmLVKLPEE 797
Cdd:COG4886 123 -NQLTDLPEElaNLTNLKELDLSNNqlTDLPEPLGNLTNLKSLDLSNNQLTDLPEELGNLTNLKELDLSNNQ-ITDLPEP 200
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235064 798 FDKLKVLQELVCSGCKrLSSLPDVMKNMQCLQILLLDGTAITKIPHIS---SLERLCLSRNeKISCLSNDIRlLSQLKWL 874
Cdd:COG4886 201 LGNLTNLEELDLSGNQ-LTDLPEPLANLTNLETLDLSNNQLTDLPELGnltNLEELDLSNN-QLTDLPPLAN-LTNLKTL 277
|
....
gi 15235064 875 DLKY 878
Cdd:COG4886 278 DLSN 281
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
673-761 |
2.93e-04 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 43.62 E-value: 2.93e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235064 673 NHSSKLENLSGLSqalNLERL-----------NLEGCTALKTLLLG-------------PENMA----SLVFLNLKGCtG 724
Cdd:cd21340 56 NQIEKIENLENLV---NLKKLylggnrisvveGLENLTNLEELHIEnqrlppgekltfdPRSLAalsnSLRVLNISGN-N 131
|
90 100 110
....*....|....*....|....*....|....*...
gi 15235064 725 LESLPKI-NLRSLKTLILSNCsNLEEFWVISETLYTLY 761
Cdd:cd21340 132 IDSLEPLaPLRNLEQLDASNN-QISDLEELLDLLSSWP 168
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PLN03210 |
PLN03210 |
Resistant to P. syringae 6; Provisional |
15-1103 |
3.60e-102 |
|
Resistant to P. syringae 6; Provisional
Pssm-ID: 215633 [Multi-domain] Cd Length: 1153 Bit Score: 349.56 E-value: 3.60e-102
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235064 15 HQVFLNFRGDELRNNFVSHLDKALRGKQINVFIDEAVEKGENLDNLFKE-IEKSRIALAIISQKYTESKWCLNEL---VK 90
Cdd:PLN03210 13 YDVFPSFSGEDVRITFLSHFLKELDRKLIIAFKDNEIERSQSLDPELKQaIRDSRIAVVVFSKNYASSSWCLNELleiVR 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235064 91 MKELEGKLVtIPIFYNVEPATVRYQKEAFGAALTKTQENDSDGQMKKWKEALTYVSLLVGFpfNSKSKEKETTLIDKIVD 170
Cdd:PLN03210 93 CKEELGQLV-IPVFYGLDPSHVRKQTGDFGEAFEKTCQNKTEDEKIQWKQALTDVANILGY--HSQNWPNEAKMIEEIAN 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235064 171 AVLQKLSKisseeSTSGSVDQGRGEEveeakaDKISGLNQRLkELEEKvaitgdkrdETRIVEVVGMPGIGKSTLLKAFY 250
Cdd:PLN03210 170 DVLGKLNL-----TPSNDFEDFVGIE------DHIAKMSSLL-HLESE---------EVRMVGIWGSSGIGKTTIARALF 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235064 251 ETWKTRFLSSALLQN--ISELVKA----------MGLgRLTGMLLKELLPDENIDEETYEPYKEKLLKNTVFIVLDGISD 318
Cdd:PLN03210 229 SRLSRQFQSSVFIDRafISKSMEIyssanpddynMKL-HLQRAFLSEILDKKDIKIYHLGAMEERLKHRKVLIFIDDLDD 307
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235064 319 EThIQKLLKDHRKWAKKGSKIVIarraVTRD--LLHEDSmVRYTYFVPLLSHRDGLNHFCHYAFRHfaahQNNKEAFMKE 396
Cdd:PLN03210 308 QD-VLDALAGQTQWFGSGSRIIV----ITKDkhFLRAHG-IDHIYEVCLPSNELALEMFCRSAFKK----NSPPDGFMEL 377
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235064 397 SKEFVRYARGHPLILKLLGEELREKSLSYWEEKLKSLPKSLSQNIrDRVLQVTYDELSQVQKDA-FLDIAC-FRSHDLVY 474
Cdd:PLN03210 378 ASEVALRAGNLPLGLNVLGSYLRGRDKEDWMDMLPRLRNGLDGKI-EKTLRVSYDGLNNKKDKAiFRHIAClFNGEKVND 456
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235064 475 VKSLLDSSGpafSKATVTIDALKDMFMIYISDSRVEMHDLLYTFAMELGPEARDDDGRGRHRIWHHHNQDnkgrlnrLLK 554
Cdd:PLN03210 457 IKLLLANSD---LDVNIGLKNLVDKSLIHVREDIVEMHSLLQEMGKEIVRAQSNEPGEREFLVDAKDICD-------VLE 526
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235064 555 RPGGSTSVRSFFLDMYvmKTD-VTLGTDYLKNMRNLRYLKFYSSHCPQectpKENI--HIPGELELPLEEVRCLHWLNFP 631
Cdd:PLN03210 527 DNTGTKKVLGITLDID--EIDeLHIHENAFKGMRNLLFLKFYTKKWDQ----KKEVrwHLPEGFDYLPPKLRLLRWDKYP 600
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235064 632 KDELPQDFIPKNLVDLKLPYSKIRQIWREEKDAPKLRWVDLNHSSKLENLSGLSQALNLERLNLEGCTALKTLLLGPENM 711
Cdd:PLN03210 601 LRCMPSNFRPENLVKLQMQGSKLEKLWDGVHSLTGLRNIDLRGSKNLKEIPDLSMATNLETLKLSDCSSLVELPSSIQYL 680
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235064 712 ASLVFLNLKGCTGLESLPK-INLRSLKTLILSNCSNLEEFWVISETLYTLYLDGTAIKTLP-----QDMVKLT------- 778
Cdd:PLN03210 681 NKLEDLDMSRCENLEILPTgINLKSLYRLNLSGCSRLKSFPDISTNISWLDLDETAIEEFPsnlrlENLDELIlcemkse 760
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235064 779 ------------------SLVKLYMKDCEMLVKLPEEFDKLKVLQELV---C--------------------SGCKRLSS 817
Cdd:PLN03210 761 klwervqpltplmtmlspSLTRLFLSDIPSLVELPSSIQNLHKLEHLEienCinletlptginleslesldlSGCSRLRT 840
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235064 818 LPDVMKNmqcLQILLLDGTAITKIP----HISSLERLCLSRNEKISCLSNDIRLLSQLKWLDLKYCtklVSIPELPTNlq 893
Cdd:PLN03210 841 FPDISTN---ISDLNLSRTGIEEVPwwieKFSNLSFLDMNGCNNLQRVSLNISKLKHLETVDFSDC---GALTEASWN-- 912
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235064 894 cldaNGCESLTTVANPLATHLPteqihSTFI--FTNCDKLDRTAKegFVPEALF-STCFPGCEVPSWFCHEAVGSVLKLN 970
Cdd:PLN03210 913 ----GSPSEVAMATDNIHSKLP-----STVCinFINCFNLDQEAL--LQQQSIFkQLILSGEEVPSYFTHRTTGASLTNI 981
|
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235064 971 LLPHWNENR-FVGIALCAVVGSLpncQEQTNSCS----VTCTFniaskdskkgdpykisfdrlvgrwnkhgnkLDKKGNK 1045
Cdd:PLN03210 982 PLLHISPCQpFFRFRACAVVDSE---SFFIISVSfdiqVCCRF------------------------------IDRLGNH 1028
|
1130 1140 1150 1160 1170 1180
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 15235064 1046 LKKTESDHVFICYTRCSNSI--KCLQDQHSGTCTPTE-----AFLEFGVTDKESRLEVLKCGLRL 1103
Cdd:PLN03210 1029 FDSPYQPHVFSVTKKGSHLVifDCCFPLNEDNAPLAElnydhVDIQFRLTNKNSQLKLKGCGIRL 1093
|
|
| TIR |
pfam01582 |
TIR domain; The Toll/interleukin-1 receptor (TIR) homology domain is an intracellular ... |
15-179 |
1.46e-40 |
|
TIR domain; The Toll/interleukin-1 receptor (TIR) homology domain is an intracellular signalling domain found in MyD88, interleukin 1 receptor and the Toll receptor. It contains three highly-conserved regions, and mediates protein-protein interactions between the Toll-like receptors (TLRs) and signal-transduction components. TIR-like motifs are also found in plant proteins thought to be involved in resistance to disease. When activated, TIR domains recruit cytoplasmic adaptor proteins MyD88 and TOLLIP (Toll interacting protein). In turn, these associate with various kinases to set off signalling cascades.
Pssm-ID: 396246 [Multi-domain] Cd Length: 165 Bit Score: 147.13 E-value: 1.46e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235064 15 HQVFLNFRGDELRNNFVSHLDKALRGKQINVFIDEA-VEKGENL-DNLFKEIEKSRIALAIISQKYTESKWCLNELVKMK 92
Cdd:pfam01582 1 YDVFLSFRGSDTREWFVSHLLKELKQKGIKLFIDDRdLEPGEAIaPELLSAIEKSRRSVVVLSPNYASSGWCLDELVKIL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235064 93 E--LEGKLVTIPIFYNVEPATVRYQKEAFGAALTKTQENDSDGQMKKWKEALTYVSLLvgfpFNSKSKEKETTLIDKIVD 170
Cdd:pfam01582 81 EcaLDLGQKVIPIFYEVDPSDVRKQTGSFGKAFKKHKKVLTEEKVLKWRGALNEVANI----WHSKSVSDESKFWKKIAY 156
|
....*....
gi 15235064 171 AVLQKLSKI 179
Cdd:pfam01582 157 DISNKLNGT 165
|
|
| TIR |
smart00255 |
Toll - interleukin 1 - resistance; |
14-148 |
7.62e-40 |
|
Toll - interleukin 1 - resistance;
Pssm-ID: 214587 [Multi-domain] Cd Length: 140 Bit Score: 144.00 E-value: 7.62e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235064 14 QHQVFLNFRG-DELRNNFVSHLDKALRGKQINVFIDEAVEKGENLDNLFKEIEKSRIALAIISQKYTESKWCLNELVKMK 92
Cdd:smart00255 1 EYDVFISYSGkEDVRNEFLSHLLEKLRGYGLCVFIDDFEPGGGDLEEIDEAIEKSRIAIVVLSPNYAESEWCLDELVAAL 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235064 93 EL---EGKLVTIPIFYNVEPATVRYQKEAFGAALTKT-QENDSDGQMKKWKEALTYVSLL 148
Cdd:smart00255 81 ENaleEGGLRVIPIFYEVIPSDVRKQPGKFRKVFKKNyLKWPEDEKEQFWKKALYAVPSK 140
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
642-878 |
2.16e-21 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 98.47 E-value: 2.16e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235064 642 KNLVDLKLPYSKIRQIWREEKDAPKLRWVDLNHSSKLENLSGLSQALNLERLNLEGCTALktlllgpENMASLVFLNLKG 721
Cdd:COG4886 50 TLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGNEEL-------SNLTNLESLDLSG 122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235064 722 cTGLESLPKI--NLRSLKTLILSNC--SNLEEFWVISETLYTLYLDGTAIKTLPQDMVKLTSLVKLYMKDCEmLVKLPEE 797
Cdd:COG4886 123 -NQLTDLPEElaNLTNLKELDLSNNqlTDLPEPLGNLTNLKSLDLSNNQLTDLPEELGNLTNLKELDLSNNQ-ITDLPEP 200
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235064 798 FDKLKVLQELVCSGCKrLSSLPDVMKNMQCLQILLLDGTAITKIPHIS---SLERLCLSRNeKISCLSNDIRlLSQLKWL 874
Cdd:COG4886 201 LGNLTNLEELDLSGNQ-LTDLPEPLANLTNLETLDLSNNQLTDLPELGnltNLEELDLSNN-QLTDLPPLAN-LTNLKTL 277
|
....
gi 15235064 875 DLKY 878
Cdd:COG4886 278 DLSN 281
|
|
| TIR_2 |
pfam13676 |
TIR domain; This is a family of Toll-like receptors. |
17-109 |
3.67e-10 |
|
TIR domain; This is a family of Toll-like receptors.
Pssm-ID: 463954 [Multi-domain] Cd Length: 118 Bit Score: 58.48 E-value: 3.67e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235064 17 VFLNFRGDElrNNFVSHLDKALRGKQINVFIDEA-VEKGENL-DNLFKEIEKSRIALAIISQKYTESKWCLNEL-VKMKE 93
Cdd:pfam13676 1 VFISYAGED--RAWAEWLADALEAAGYRVWLDRWdIRPGDDWvEEIEEAIENSDRVLVVLSPNYLESPWCRAEWeAALAD 78
|
90
....*....|....*.
gi 15235064 94 LEGKLVTIPIFYNVEP 109
Cdd:pfam13676 79 PEGRKRLIPVRLECDL 94
|
|
| C-JID |
pfam20160 |
C-JID domain; C-terminal jelly roll/Ig-like domain (C-JID) was defined in cryogenic electron ... |
949-990 |
1.54e-09 |
|
C-JID domain; C-terminal jelly roll/Ig-like domain (C-JID) was defined in cryogenic electron microscopy (cryoEM) structures of plant intracellular immune receptors containing Toll/interleukin-1 receptor (TIR, PF01582), nucleotide-binding (NB-ARC, PF00931) and leucine-rich repeat (LRR) domains (TIR-NLRs). Structurally, the C-JID core is represented by a beta-sandwich made up of 8 to 9 beta-strands. C-JID matches the so-called post LRR domain originally detected via a set of MEME motifs. The domain showed a strong distribution bias towards TIR-NLRs of dicotyledonous plant species despite broader taxonomic distribution of TIR-NLR in plant groups. Structure-function analyses of cryoEM structures suggest that C-JID domains play a role in substrate-recognition, such as binding to effector proteins from pathogens, and thus are involved in the initiation of signaling by TIR-NLR receptors. Presence of C-JID (or post-LRR) and its importance for the function of Arabidopsis TIR-NLR RPS4 that partners with RRS1 for effector recognition suggest that C-JID has additional functions.
Pssm-ID: 466313 Cd Length: 108 Bit Score: 56.30 E-value: 1.54e-09
10 20 30 40
....*....|....*....|....*....|....*....|..
gi 15235064 949 FPGCEVPSWFCHEAVGSVLKLNLLPHWNENRFVGIALCAVVG 990
Cdd:pfam20160 1 LPGSQIPEWFNHQSTGSSISIKLPENWYNDNFLGFAVCAVGS 42
|
|
| PLN03194 |
PLN03194 |
putative disease resistance protein; Provisional |
12-184 |
1.94e-08 |
|
putative disease resistance protein; Provisional
Pssm-ID: 215626 [Multi-domain] Cd Length: 187 Bit Score: 55.60 E-value: 1.94e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235064 12 PQQHQVFLNFRGDELRNNFVSHLDKALRGKQINVFIDEAVEK-GENL-DNLFKEIEKSRIALAIISQKYTESKWCLNELV 89
Cdd:PLN03194 24 AKPCDVFINHRGIDTKRTIATLLYDHLSRLNLRPFLDNKNMKpGDKLfDKINSAIRNCKVGVAVFSPRYCESYFCLHELA 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235064 90 KMkeLEGKLVTIPIFYNVEPATVRyqkeafgaalTKTQENDSDGQMKKWKEALTYVSLLVGFPFNSkSKEKETTLIDKIV 169
Cdd:PLN03194 104 LI--MESKKRVIPIFCDVKPSQLR----------VVDNGTCPDEEIRRFNWALEEAKYTVGLTFDS-LKGNWSEVVTMAS 170
|
170
....*....|....*
gi 15235064 170 DAVLQKLSKISSEES 184
Cdd:PLN03194 171 DAVIKNLIELEEEKS 185
|
|
| NB-ARC |
pfam00931 |
NB-ARC domain; |
217-452 |
1.16e-05 |
|
NB-ARC domain;
Pssm-ID: 395745 [Multi-domain] Cd Length: 245 Bit Score: 48.14 E-value: 1.16e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235064 217 EKVAITGDKRDETRIVEVVGMPGIGKSTLLKAFYETWKT---RFLSSALLQ-----NISELVKAMGLgrltgMLLKELLP 288
Cdd:pfam00931 6 EKVIGKLSEKDEPGIVGIHGMGGVGKTTLAAQIFNDFDEvegHFDSVAWVVvsktfTISTLQQTILQ-----NLGLSEDD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235064 289 DENIDE-ETYEPYKEKLLKNTVFIVLDGISDETHIQKlLKDHRKWAKKGSKIVIARRavTRDLLHEDSMVRYTYFVPLLS 367
Cdd:pfam00931 81 WDNKEEgELARKIRRALLTKRFLLVLDDVWDEEDWDK-IGIPLPDRENGCRVLLTTR--SEEVAGRVGGPSDPHEVELLE 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235064 368 HRDGLNHFCHYAFRhfaAHQNNKEAFMKESKEFVRYARGHPLILKLLGEELR-EKSLSYWE---EKLKSLPKSL--SQNI 441
Cdd:pfam00931 158 PDEAWELFENKVFP---KTLGECELLEDVAKEIVEKCRGLPLALKVLGGLLScKKTVEEWKhvyDVLQSELKSNsySLNS 234
|
250
....*....|.
gi 15235064 442 RDRVLQVTYDE 452
Cdd:pfam00931 235 VRSILQLSYEN 245
|
|
| NACHT |
COG5635 |
Predicted NTPase, NACHT family domain [Signal transduction mechanisms]; |
212-439 |
1.30e-04 |
|
Predicted NTPase, NACHT family domain [Signal transduction mechanisms];
Pssm-ID: 444362 [Multi-domain] Cd Length: 935 Bit Score: 46.34 E-value: 1.30e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235064 212 LKELEEKVAITGDKRDETRIVeVVGMPGIGKSTLLK-AFYETWKTRFLSSA---LLQNISELVKAMGLGRLtgmLLKELL 287
Cdd:COG5635 164 LERIESLKRLELLEAKKKRLL-ILGEPGSGKTTLLRyLALELAERYLDAEDpipILIELRDLAEEASLEDL---LAEALE 239
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235064 288 PDENIDEETYepykEKLLKNT-VFIVLDG---ISDETHIQKLLKDHRKWAKK--GSKIVIARRAVTRDLLHEDSMVRYtY 361
Cdd:COG5635 240 KRGGEPEDAL----ERLLRNGrLLLLLDGldeVPDEADRDEVLNQLRRFLERypKARVIITSRPEGYDSSELEGFEVL-E 314
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235064 362 FVPLlsHRDGLNHFCHyafRHFAAHQNNKEAFMK---ESKEFVRYARgHPLILKLLgeelreksLSYWEEKlKSLPKSLS 438
Cdd:COG5635 315 LAPL--SDEQIEEFLK---KWFEATERKAERLLEaleENPELRELAR-NPLLLTLL--------ALLLRER-GELPDTRA 379
|
.
gi 15235064 439 Q 439
Cdd:COG5635 380 E 380
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
673-761 |
2.93e-04 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 43.62 E-value: 2.93e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235064 673 NHSSKLENLSGLSqalNLERL-----------NLEGCTALKTLLLG-------------PENMA----SLVFLNLKGCtG 724
Cdd:cd21340 56 NQIEKIENLENLV---NLKKLylggnrisvveGLENLTNLEELHIEnqrlppgekltfdPRSLAalsnSLRVLNISGN-N 131
|
90 100 110
....*....|....*....|....*....|....*...
gi 15235064 725 LESLPKI-NLRSLKTLILSNCsNLEEFWVISETLYTLY 761
Cdd:cd21340 132 IDSLEPLaPLRNLEQLDASNN-QISDLEELLDLLSSWP 168
|
|
| AAA_16 |
pfam13191 |
AAA ATPase domain; This family of domains contain a P-loop motif that is characteriztic of the ... |
192-341 |
2.27e-03 |
|
AAA ATPase domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily.
Pssm-ID: 433025 [Multi-domain] Cd Length: 167 Bit Score: 40.18 E-value: 2.27e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235064 192 GRGEEVEeakadkisglnqRLKELEEKVAitgdkRDETRIVEVVGMPGIGKSTLLKAFYETWKTR---FLSSALLQNISE 268
Cdd:pfam13191 4 GREEELE------------QLLDALDRVR-----SGRPPSVLLTGEAGTGKTTLLRELLRALERDggyFLRGKCDENLPY 66
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 15235064 269 LVKAMGLGRLTgmLLKELLPDENIDEEtyEPYKEKLLKNTVFIVLDGISDETHIQKLLKDHRKWAKKGSKIVI 341
Cdd:pfam13191 67 SPLLEALTREG--LLRQLLDELESSLL--EAWRAALLEALAPVPELPGDLAERLLDLLLRLLDLLARGERPLV 135
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
673-818 |
3.47e-03 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 40.15 E-value: 3.47e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235064 673 NHSSKLENLSGLSqalNLERL-----------NLEGCTALKTLLLGPENMASLvflnlkgcTGLEslpkiNLRSLKTLIL 741
Cdd:cd21340 34 NKITKIENLEFLT---NLTHLylqnnqiekieNLENLVNLKKLYLGGNRISVV--------EGLE-----NLTNLEELHI 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235064 742 SN---------CSNLEEFWVISETLYTLYLDGTAIKTLpQDMVKLTSLVKLYMKDCemlvklpeEFDKLKVLQELVcSGC 812
Cdd:cd21340 98 ENqrlppgeklTFDPRSLAALSNSLRVLNISGNNIDSL-EPLAPLRNLEQLDASNN--------QISDLEELLDLL-SSW 167
|
....*.
gi 15235064 813 KRLSSL 818
Cdd:cd21340 168 PSLREL 173
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
731-911 |
3.70e-03 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 41.07 E-value: 3.70e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235064 731 INLRSLKTLILSNCSNLEEFWVISETLYTLYLDGTAIKTLPQDMVKLTSLVKLYMKDCEMLVKLPEEFDKLKVLQELVCS 810
Cdd:COG4886 1 LLLLLLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15235064 811 GCKRLSSLPDVMKNMQCLQILLLDGTaiTKIPHISSLERLCLSRNeKISCLSNDIRLLSQLKWLDLKYcTKLVSIPE-LP 889
Cdd:COG4886 81 LLSLLLLGLTDLGDLTNLTELDLSGN--EELSNLTNLESLDLSGN-QLTDLPEELANLTNLKELDLSN-NQLTDLPEpLG 156
|
170 180
....*....|....*....|....
gi 15235064 890 --TNLQCLDANGCEsLTTVANPLA 911
Cdd:COG4886 157 nlTNLKSLDLSNNQ-LTDLPEELG 179
|
|
| LRR_3 |
pfam07725 |
Leucine Rich Repeat; This Pfam entry includes some LRRs that fail to be detected by the ... |
643-662 |
5.93e-03 |
|
Leucine Rich Repeat; This Pfam entry includes some LRRs that fail to be detected by the pfam00560 model.
Pssm-ID: 429621 [Multi-domain] Cd Length: 20 Bit Score: 35.39 E-value: 5.93e-03
|
| |
