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Conserved domains on  [gi|42566953|ref|NP_193673|]
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Long-chain fatty alcohol dehydrogenase family protein [Arabidopsis thaliana]

Protein Classification

GMC family oxidoreductase( domain architecture ID 17335521)

GMC (glucose-methanol-choline) family oxidoreductase is a flavoprotein that catalyzes the oxidation of an alcohol moiety to the corresponding aldehyde with the concomitant reduction of flavin adenine dinucleotide (FAD)

EC:  1.-.-.-
Gene Ontology:  GO:0016491|GO:0050660

Graphical summary

 Zoom to residue level

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List of domain hits

Name Accession Description Interval E-value
GMC_oxred_N pfam00732
GMC oxidoreductase; This family of proteins bind FAD as a cofactor.
271-486 3.87e-93

GMC oxidoreductase; This family of proteins bind FAD as a cofactor.


:

Pssm-ID: 366272 [Multi-domain]  Cd Length: 218  Bit Score: 288.80  E-value: 3.87e-93
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42566953   271 MDDMYLSGGLLATSDTNVVIL-AGSTVGGGSTINWSASIKTPEHVMKEWAEKSKLEMFGSDLYREAMDVVCKRMGVQCGF 349
Cdd:pfam00732   1 YDYLYEGGGSAGSVNGRRMILpAGSTVGGGSSVNWSACIRTPAAVLDEWASEFGLEGWGYDDYLPYMDKVEGPLGVTTKG 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42566953   350 VEEGFNNEVLRKGCEKLGLPVKNIPRNAPSDHYCGFCCLGCKKGQKQGTSETWLVDLVESdNGLILPGCQATEVMYDceq 429
Cdd:pfam00732  81 IEESPLNQALLKAAEELGYPVEAVPRNSNGCHYCGFCGLGCPTGAKQSTARTWLRPALER-NLRILTGAKAEKIIIL--- 156
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 42566953   430 GKKKKATGVAFAFGEEI---YVVESRVTIVACGALRTPHLLKRSGL-KNSN-IGRNLCLHPV 486
Cdd:pfam00732 157 GRGGRAVGVEARDGGGGikrLITAAKEVVVAAGALNTPPLLLRSGLgKNPHpVGKNLQLHPV 218
BetA super family cl34456
Choline dehydrogenase or related flavoprotein [Lipid transport and metabolism, General ...
243-712 1.62e-38

Choline dehydrogenase or related flavoprotein [Lipid transport and metabolism, General function prediction only]; Choline dehydrogenase or related flavoprotein is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway


The actual alignment was detected with superfamily member COG2303:

Pssm-ID: 441878 [Multi-domain]  Cd Length: 531  Bit Score: 150.36  E-value: 1.62e-38
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42566953 243 AKAGYKVLVIESG--NYYARSKLSLLEGQAMDD-----MYLSGGLLATSDTNVVILAGSTVGGGSTINWSASIK-TPEHv 314
Cdd:COG2303  25 EDAGLRVLLLEAGgrDDDPLIRMPAGYAKLLGNprydwRYETEPQPGLNGRRLYWPRGKVLGGSSSINGMIYVRgQPED- 103
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42566953 315 MKEWAE----------------KSKLEMFGSDLYR---EAMDVVCKRMgvqcgfveEGFNNEVLRKGCEKLGLPVkNIPR 375
Cdd:COG2303 104 FDLWAQlgnqgwgyddvlpyfkRAEDNERGADAYHgrsGPLPVSDPPL--------PNPLSDAFIEAAEELGIPR-ADDF 174
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42566953 376 NAPSDHYCGFCCLGCKKGQKQGTSETWLVDLVESDNGLILPGCQATEVMYDceqgkKKKATGVAFAF-GEEIYVVESRVT 454
Cdd:COG2303 175 NGGACEGCGFCQVTCRNGARWSAARAYLPPALKRPNLTVRTGALVTRILFD-----GGRATGVEYRDdGEEHTVRAAREV 249
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42566953 455 IVACGALRTPHLLKRSGLKNSN---------------IGRNLCLHPVVMAWGWFPEEDKWPEKKKKSYEG--------GI 511
Cdd:COG2303 250 ILAAGAINSPQLLLLSGIGPAShlrehgipvvhdlpgVGRNLQDHLEVSVVFRFKEPVTLNKSLRKARIGlqylltrsGP 329
                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42566953 512 MTAMSSVVIEETHSSygemviqtPAL-HPGMFSGIIPWTSSKDFKTRMLKFSR--TAHIFALL-RDKGTGTIDSKtyiD- 586
Cdd:COG2303 330 LTSNVAEAGGFFRSD--------PGLeRPDLQFHFLPLGLTPRWGKKALHDGHgfTAHVEQLRpESRGRVTLDSA---Dp 398
                       410       420       430       440       450       460       470       480
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42566953 587 ---------YNLNDEDEESLKNGLERVLKILAAAGAEE-IGTHHSEGRSlnvrtASSLEIERFVREESSkplkdlsgqiC 656
Cdd:COG2303 399 lgaplirpnYLSDENDRRVLVAGVRLAREIAAQPALAPyRGEEILPGPD-----VQSDEELAFIRARAY----------T 463
                       490       500       510       520       530
                ....*....|....*....|....*....|....*....|....*....|....*.
gi 42566953 657 SAHQMGSCRMGIRPEeSAVRPTGETWEVERLFVADTSVFPTALGVNPMVTVQSIAY 712
Cdd:COG2303 464 IYHPVGTCRMGTDPD-SVVDPRLRVHGVENLRVVDASVMPTITSGNTNAPTIMLAE 518
 
Name Accession Description Interval E-value
GMC_oxred_N pfam00732
GMC oxidoreductase; This family of proteins bind FAD as a cofactor.
271-486 3.87e-93

GMC oxidoreductase; This family of proteins bind FAD as a cofactor.


Pssm-ID: 366272 [Multi-domain]  Cd Length: 218  Bit Score: 288.80  E-value: 3.87e-93
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42566953   271 MDDMYLSGGLLATSDTNVVIL-AGSTVGGGSTINWSASIKTPEHVMKEWAEKSKLEMFGSDLYREAMDVVCKRMGVQCGF 349
Cdd:pfam00732   1 YDYLYEGGGSAGSVNGRRMILpAGSTVGGGSSVNWSACIRTPAAVLDEWASEFGLEGWGYDDYLPYMDKVEGPLGVTTKG 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42566953   350 VEEGFNNEVLRKGCEKLGLPVKNIPRNAPSDHYCGFCCLGCKKGQKQGTSETWLVDLVESdNGLILPGCQATEVMYDceq 429
Cdd:pfam00732  81 IEESPLNQALLKAAEELGYPVEAVPRNSNGCHYCGFCGLGCPTGAKQSTARTWLRPALER-NLRILTGAKAEKIIIL--- 156
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 42566953   430 GKKKKATGVAFAFGEEI---YVVESRVTIVACGALRTPHLLKRSGL-KNSN-IGRNLCLHPV 486
Cdd:pfam00732 157 GRGGRAVGVEARDGGGGikrLITAAKEVVVAAGALNTPPLLLRSGLgKNPHpVGKNLQLHPV 218
BetA COG2303
Choline dehydrogenase or related flavoprotein [Lipid transport and metabolism, General ...
243-712 1.62e-38

Choline dehydrogenase or related flavoprotein [Lipid transport and metabolism, General function prediction only]; Choline dehydrogenase or related flavoprotein is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway


Pssm-ID: 441878 [Multi-domain]  Cd Length: 531  Bit Score: 150.36  E-value: 1.62e-38
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42566953 243 AKAGYKVLVIESG--NYYARSKLSLLEGQAMDD-----MYLSGGLLATSDTNVVILAGSTVGGGSTINWSASIK-TPEHv 314
Cdd:COG2303  25 EDAGLRVLLLEAGgrDDDPLIRMPAGYAKLLGNprydwRYETEPQPGLNGRRLYWPRGKVLGGSSSINGMIYVRgQPED- 103
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42566953 315 MKEWAE----------------KSKLEMFGSDLYR---EAMDVVCKRMgvqcgfveEGFNNEVLRKGCEKLGLPVkNIPR 375
Cdd:COG2303 104 FDLWAQlgnqgwgyddvlpyfkRAEDNERGADAYHgrsGPLPVSDPPL--------PNPLSDAFIEAAEELGIPR-ADDF 174
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42566953 376 NAPSDHYCGFCCLGCKKGQKQGTSETWLVDLVESDNGLILPGCQATEVMYDceqgkKKKATGVAFAF-GEEIYVVESRVT 454
Cdd:COG2303 175 NGGACEGCGFCQVTCRNGARWSAARAYLPPALKRPNLTVRTGALVTRILFD-----GGRATGVEYRDdGEEHTVRAAREV 249
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42566953 455 IVACGALRTPHLLKRSGLKNSN---------------IGRNLCLHPVVMAWGWFPEEDKWPEKKKKSYEG--------GI 511
Cdd:COG2303 250 ILAAGAINSPQLLLLSGIGPAShlrehgipvvhdlpgVGRNLQDHLEVSVVFRFKEPVTLNKSLRKARIGlqylltrsGP 329
                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42566953 512 MTAMSSVVIEETHSSygemviqtPAL-HPGMFSGIIPWTSSKDFKTRMLKFSR--TAHIFALL-RDKGTGTIDSKtyiD- 586
Cdd:COG2303 330 LTSNVAEAGGFFRSD--------PGLeRPDLQFHFLPLGLTPRWGKKALHDGHgfTAHVEQLRpESRGRVTLDSA---Dp 398
                       410       420       430       440       450       460       470       480
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42566953 587 ---------YNLNDEDEESLKNGLERVLKILAAAGAEE-IGTHHSEGRSlnvrtASSLEIERFVREESSkplkdlsgqiC 656
Cdd:COG2303 399 lgaplirpnYLSDENDRRVLVAGVRLAREIAAQPALAPyRGEEILPGPD-----VQSDEELAFIRARAY----------T 463
                       490       500       510       520       530
                ....*....|....*....|....*....|....*....|....*....|....*.
gi 42566953 657 SAHQMGSCRMGIRPEeSAVRPTGETWEVERLFVADTSVFPTALGVNPMVTVQSIAY 712
Cdd:COG2303 464 IYHPVGTCRMGTDPD-SVVDPRLRVHGVENLRVVDASVMPTITSGNTNAPTIMLAE 518
GMC_oxred_C pfam05199
GMC oxidoreductase; This domain found associated with pfam00732.
572-714 9.58e-24

GMC oxidoreductase; This domain found associated with pfam00732.


Pssm-ID: 398739 [Multi-domain]  Cd Length: 143  Bit Score: 97.47  E-value: 9.58e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42566953   572 RDKGTGTIDSK-------TYIDYNLNDEDEESLKNGLERVLKILAAAGA----EEIGTHHSEGRSLNVRTASslEIERFV 640
Cdd:pfam05199   2 RSRGRVTLSSSdptglpvIDPNYLSDPADLAALRAALRLARRILAAAGLvlgvELTPGPVPEVSDAAVTSDD--ELLAYI 79
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 42566953   641 REESSKplkdlsgqicSAHQMGSCRMGIRPEESAVRPTGETWEVERLFVADTSVFPTALGVNPMVTVQSIAYCI 714
Cdd:pfam05199  80 RAAAST----------SYHPMGTCRMGADPDDAVVDPDLRVHGVDNLRVVDASVFPSSPSGNPTLTIYALAERA 143
Rv0697 TIGR03970
dehydrogenase, Rv0697 family; This model describes a set of dehydrogenases belonging to the ...
455-711 2.59e-05

dehydrogenase, Rv0697 family; This model describes a set of dehydrogenases belonging to the glucose-methanol-choline oxidoreductase (GMC oxidoreductase) family. Members of the present family are restricted to Actinobacterial genome contexts containing also members of families TIGR03962 and TIGR03969 (the mycofactocin system), and are proposed to be uniform in function.


Pssm-ID: 274888 [Multi-domain]  Cd Length: 487  Bit Score: 47.50  E-value: 2.59e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42566953   455 IVAC-GALRTPHLLKRSG--------------LKNSNIGRNLCLHP-VVMAWGWFPEEDKWPEKKKKSYeggiMTAMSSV 518
Cdd:TIGR03970 247 VVLCaGAVESAHLLLLSGigpaeqlraagiavVLDLPVGSDFVDHPeWVLPYRWRPTHDRPPTSPVLET----VLNTADI 322
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42566953   519 VIEETHSSYGEMVIQTPALHPGMfsGIipwtsskdfktrmlkfsrtahifALLRDKGTGTI-------DSKTYIDYNLND 591
Cdd:TIGR03970 323 EIRPYTAGFTALVPGSPRDDPHL--GV-----------------------ALMRPHSRGRIrlasadpADPPRIEHRYDS 377
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42566953   592 E--DEESLKNGLERVLKILAAagaeeigthhsegrslnvrTASSLEIERFVREESSKPLKDLSGQicSAHQMGSCRMGIR 669
Cdd:TIGR03970 378 SaaDRAALRAGAALAHELLGS-------------------PELGPLLEPAVREGEASWVLARLAT--SQHLCGSCRMGGR 436
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|...
gi 42566953   670 PEESAV-RPTGETWEVERLFVADTSVFPTALGVNPMVTVQSIA 711
Cdd:TIGR03970 437 DDPGAVvDARCRVRGVEGLWVVDGSILPVIPSRGPHATAVMVA 479
PRK02106 PRK02106
choline dehydrogenase; Validated
391-493 7.10e-04

choline dehydrogenase; Validated


Pssm-ID: 235000 [Multi-domain]  Cd Length: 560  Bit Score: 42.90  E-value: 7.10e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42566953  391 KKGQKQGTSETWLVDLVESDNGLILPGCQATEVMYDceqgkKKKATGVAFAFGEEIYVVE-SRVTIVACGALRTPHLLKR 469
Cdd:PRK02106 195 TNGRRWSAARAYLDPALKRPNLTIVTHALTDRILFE-----GKRAVGVEYERGGGRETARaRREVILSAGAINSPQLLQL 269
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 42566953  470 SG------LKNSNI---------GRNL-----------CLHPVVM--AWGWF 493
Cdd:PRK02106 270 SGigpaehLKELGIpvvhdlpgvGENLqdhlevyiqyeCKQPVSLypALKWW 321
PRK02106 PRK02106
choline dehydrogenase; Validated
635-697 8.49e-03

choline dehydrogenase; Validated


Pssm-ID: 235000 [Multi-domain]  Cd Length: 560  Bit Score: 39.43  E-value: 8.49e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 42566953  635 EIERFVREESSkplkdlsgqicSA-HQMGSCRMGiRPEESAVRPTGETWEVERLFVADTSVFPT 697
Cdd:PRK02106 459 EIDAFVREHAE-----------TAyHPSCTCKMG-TDPMAVVDPEGRVHGVEGLRVVDASIMPT 510
 
Name Accession Description Interval E-value
GMC_oxred_N pfam00732
GMC oxidoreductase; This family of proteins bind FAD as a cofactor.
271-486 3.87e-93

GMC oxidoreductase; This family of proteins bind FAD as a cofactor.


Pssm-ID: 366272 [Multi-domain]  Cd Length: 218  Bit Score: 288.80  E-value: 3.87e-93
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42566953   271 MDDMYLSGGLLATSDTNVVIL-AGSTVGGGSTINWSASIKTPEHVMKEWAEKSKLEMFGSDLYREAMDVVCKRMGVQCGF 349
Cdd:pfam00732   1 YDYLYEGGGSAGSVNGRRMILpAGSTVGGGSSVNWSACIRTPAAVLDEWASEFGLEGWGYDDYLPYMDKVEGPLGVTTKG 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42566953   350 VEEGFNNEVLRKGCEKLGLPVKNIPRNAPSDHYCGFCCLGCKKGQKQGTSETWLVDLVESdNGLILPGCQATEVMYDceq 429
Cdd:pfam00732  81 IEESPLNQALLKAAEELGYPVEAVPRNSNGCHYCGFCGLGCPTGAKQSTARTWLRPALER-NLRILTGAKAEKIIIL--- 156
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 42566953   430 GKKKKATGVAFAFGEEI---YVVESRVTIVACGALRTPHLLKRSGL-KNSN-IGRNLCLHPV 486
Cdd:pfam00732 157 GRGGRAVGVEARDGGGGikrLITAAKEVVVAAGALNTPPLLLRSGLgKNPHpVGKNLQLHPV 218
BetA COG2303
Choline dehydrogenase or related flavoprotein [Lipid transport and metabolism, General ...
243-712 1.62e-38

Choline dehydrogenase or related flavoprotein [Lipid transport and metabolism, General function prediction only]; Choline dehydrogenase or related flavoprotein is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway


Pssm-ID: 441878 [Multi-domain]  Cd Length: 531  Bit Score: 150.36  E-value: 1.62e-38
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42566953 243 AKAGYKVLVIESG--NYYARSKLSLLEGQAMDD-----MYLSGGLLATSDTNVVILAGSTVGGGSTINWSASIK-TPEHv 314
Cdd:COG2303  25 EDAGLRVLLLEAGgrDDDPLIRMPAGYAKLLGNprydwRYETEPQPGLNGRRLYWPRGKVLGGSSSINGMIYVRgQPED- 103
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42566953 315 MKEWAE----------------KSKLEMFGSDLYR---EAMDVVCKRMgvqcgfveEGFNNEVLRKGCEKLGLPVkNIPR 375
Cdd:COG2303 104 FDLWAQlgnqgwgyddvlpyfkRAEDNERGADAYHgrsGPLPVSDPPL--------PNPLSDAFIEAAEELGIPR-ADDF 174
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42566953 376 NAPSDHYCGFCCLGCKKGQKQGTSETWLVDLVESDNGLILPGCQATEVMYDceqgkKKKATGVAFAF-GEEIYVVESRVT 454
Cdd:COG2303 175 NGGACEGCGFCQVTCRNGARWSAARAYLPPALKRPNLTVRTGALVTRILFD-----GGRATGVEYRDdGEEHTVRAAREV 249
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42566953 455 IVACGALRTPHLLKRSGLKNSN---------------IGRNLCLHPVVMAWGWFPEEDKWPEKKKKSYEG--------GI 511
Cdd:COG2303 250 ILAAGAINSPQLLLLSGIGPAShlrehgipvvhdlpgVGRNLQDHLEVSVVFRFKEPVTLNKSLRKARIGlqylltrsGP 329
                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42566953 512 MTAMSSVVIEETHSSygemviqtPAL-HPGMFSGIIPWTSSKDFKTRMLKFSR--TAHIFALL-RDKGTGTIDSKtyiD- 586
Cdd:COG2303 330 LTSNVAEAGGFFRSD--------PGLeRPDLQFHFLPLGLTPRWGKKALHDGHgfTAHVEQLRpESRGRVTLDSA---Dp 398
                       410       420       430       440       450       460       470       480
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42566953 587 ---------YNLNDEDEESLKNGLERVLKILAAAGAEE-IGTHHSEGRSlnvrtASSLEIERFVREESSkplkdlsgqiC 656
Cdd:COG2303 399 lgaplirpnYLSDENDRRVLVAGVRLAREIAAQPALAPyRGEEILPGPD-----VQSDEELAFIRARAY----------T 463
                       490       500       510       520       530
                ....*....|....*....|....*....|....*....|....*....|....*.
gi 42566953 657 SAHQMGSCRMGIRPEeSAVRPTGETWEVERLFVADTSVFPTALGVNPMVTVQSIAY 712
Cdd:COG2303 464 IYHPVGTCRMGTDPD-SVVDPRLRVHGVENLRVVDASVMPTITSGNTNAPTIMLAE 518
GMC_oxred_C pfam05199
GMC oxidoreductase; This domain found associated with pfam00732.
572-714 9.58e-24

GMC oxidoreductase; This domain found associated with pfam00732.


Pssm-ID: 398739 [Multi-domain]  Cd Length: 143  Bit Score: 97.47  E-value: 9.58e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42566953   572 RDKGTGTIDSK-------TYIDYNLNDEDEESLKNGLERVLKILAAAGA----EEIGTHHSEGRSLNVRTASslEIERFV 640
Cdd:pfam05199   2 RSRGRVTLSSSdptglpvIDPNYLSDPADLAALRAALRLARRILAAAGLvlgvELTPGPVPEVSDAAVTSDD--ELLAYI 79
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 42566953   641 REESSKplkdlsgqicSAHQMGSCRMGIRPEESAVRPTGETWEVERLFVADTSVFPTALGVNPMVTVQSIAYCI 714
Cdd:pfam05199  80 RAAAST----------SYHPMGTCRMGADPDDAVVDPDLRVHGVDNLRVVDASVFPSSPSGNPTLTIYALAERA 143
Rv0697 TIGR03970
dehydrogenase, Rv0697 family; This model describes a set of dehydrogenases belonging to the ...
455-711 2.59e-05

dehydrogenase, Rv0697 family; This model describes a set of dehydrogenases belonging to the glucose-methanol-choline oxidoreductase (GMC oxidoreductase) family. Members of the present family are restricted to Actinobacterial genome contexts containing also members of families TIGR03962 and TIGR03969 (the mycofactocin system), and are proposed to be uniform in function.


Pssm-ID: 274888 [Multi-domain]  Cd Length: 487  Bit Score: 47.50  E-value: 2.59e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42566953   455 IVAC-GALRTPHLLKRSG--------------LKNSNIGRNLCLHP-VVMAWGWFPEEDKWPEKKKKSYeggiMTAMSSV 518
Cdd:TIGR03970 247 VVLCaGAVESAHLLLLSGigpaeqlraagiavVLDLPVGSDFVDHPeWVLPYRWRPTHDRPPTSPVLET----VLNTADI 322
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42566953   519 VIEETHSSYGEMVIQTPALHPGMfsGIipwtsskdfktrmlkfsrtahifALLRDKGTGTI-------DSKTYIDYNLND 591
Cdd:TIGR03970 323 EIRPYTAGFTALVPGSPRDDPHL--GV-----------------------ALMRPHSRGRIrlasadpADPPRIEHRYDS 377
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42566953   592 E--DEESLKNGLERVLKILAAagaeeigthhsegrslnvrTASSLEIERFVREESSKPLKDLSGQicSAHQMGSCRMGIR 669
Cdd:TIGR03970 378 SaaDRAALRAGAALAHELLGS-------------------PELGPLLEPAVREGEASWVLARLAT--SQHLCGSCRMGGR 436
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|...
gi 42566953   670 PEESAV-RPTGETWEVERLFVADTSVFPTALGVNPMVTVQSIA 711
Cdd:TIGR03970 437 DDPGAVvDARCRVRGVEGLWVVDGSILPVIPSRGPHATAVMVA 479
PRK02106 PRK02106
choline dehydrogenase; Validated
391-493 7.10e-04

choline dehydrogenase; Validated


Pssm-ID: 235000 [Multi-domain]  Cd Length: 560  Bit Score: 42.90  E-value: 7.10e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42566953  391 KKGQKQGTSETWLVDLVESDNGLILPGCQATEVMYDceqgkKKKATGVAFAFGEEIYVVE-SRVTIVACGALRTPHLLKR 469
Cdd:PRK02106 195 TNGRRWSAARAYLDPALKRPNLTIVTHALTDRILFE-----GKRAVGVEYERGGGRETARaRREVILSAGAINSPQLLQL 269
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 42566953  470 SG------LKNSNI---------GRNL-----------CLHPVVM--AWGWF 493
Cdd:PRK02106 270 SGigpaehLKELGIpvvhdlpgvGENLqdhlevyiqyeCKQPVSLypALKWW 321
PRK02106 PRK02106
choline dehydrogenase; Validated
635-697 8.49e-03

choline dehydrogenase; Validated


Pssm-ID: 235000 [Multi-domain]  Cd Length: 560  Bit Score: 39.43  E-value: 8.49e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 42566953  635 EIERFVREESSkplkdlsgqicSA-HQMGSCRMGiRPEESAVRPTGETWEVERLFVADTSVFPT 697
Cdd:PRK02106 459 EIDAFVREHAE-----------TAyHPSCTCKMG-TDPMAVVDPEGRVHGVEGLRVVDASIMPT 510
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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