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Conserved domains on  [gi|240256006|ref|NP_193640|]
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NB-ARC domain-containing disease resistance protein [Arabidopsis thaliana]

Protein Classification

leucine-rich repeat domain-containing protein( domain architecture ID 11469232)

leucine-rich repeat (LRR) domain-containing protein may participate in protein-protein interactions

Gene Ontology:  GO:0005515
PubMed:  11751054|7583641|14747988
SCOP:  4003523

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
620-904 1.24e-26

Leucine-rich repeat (LRR) protein [Transcription];


:

Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 114.26  E-value: 1.24e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256006  620 LKDSTNDFSTMPILTRLLLRNCTRLKRLPQLRPLTNLQILDACGATDLVEMLEVCLEEKKELRILDMSKTSLPELADTIA 699
Cdd:COG4886    14 LLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLG 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256006  700 DVVNLNKLLLRNCslieelPSIEKLTHLEVFDVSGCiKLKNINGSFGEMSYLHEVNLSETNLSELPDKISELSNLKELII 779
Cdd:COG4886    94 DLTNLTELDLSGN------EELSNLTNLESLDLSGN-QLTDLPEELANLTNLKELDLSNNQLTDLPEPLGNLTNLKSLDL 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256006  780 RKCsKLKTLPN-LEKLTNLEIFDVSGcTELETIEGSFENLSCLHKVNLSETNLGELPNKISELSNLKELILRNCsKLKAL 858
Cdd:COG4886   167 SNN-QLTDLPEeLGNLTNLKELDLSN-NQITDLPEPLGNLTNLEELDLSGNQLTDLPEPLANLTNLETLDLSNN-QLTDL 243

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*.
gi 240256006  859 PNLEKLTHLVIFDVSGcTNLDKIEESFEsMSYLCEVNLSGTNLKTF 904
Cdd:COG4886   244 PELGNLTNLEELDLSN-NQLTDLPPLAN-LTNLKTLDLSNNQLTDL 287
NACHT super family cl26020
Predicted NTPase, NACHT family domain [Signal transduction mechanisms];
27-233 8.76e-09

Predicted NTPase, NACHT family domain [Signal transduction mechanisms];


The actual alignment was detected with superfamily member COG5635:

Pssm-ID: 444362 [Multi-domain]  Cd Length: 935  Bit Score: 59.82  E-value: 8.76e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256006   27 SKTVLVGEAGIGKTWLAKEVSQRVTQEKYN-----VLWLHLnKKIEDEKSLYEILAAQLSIIYEFeegeepdeldyPLES 101
Cdd:COG5635   181 KRLLILGEPGSGKTTLLRYLALELAERYLDaedpiPILIEL-RDLAEEASLEDLLAEALEKRGGE-----------PEDA 248

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256006  102 LKEKIKEemikhkkDNLLLILD--DEGSMTTE-EDVMQELNlqDFLKEYSAVKILVTRR----DEREEKESTTIKVGPLT 174
Cdd:COG5635   249 LERLLRN-------GRLLLLLDglDEVPDEADrDEVLNQLR--RFLERYPKARVIITSRpegyDSSELEGFEVLELAPLS 319

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 240256006  175 EKESLDLLHDAEDLLTSFTSEdwpvLLKRLCDNKEIKE----P---TLMSCILSKSKGLPAAIVVL 233
Cdd:COG5635   320 DEQIEEFLKKWFEATERKAER----LLEALEENPELRElarnPlllTLLALLLRERGELPDTRAEL 381
PLN03210 super family cl33662
Resistant to P. syringae 6; Provisional
 455-569 1.16e-05

Resistant to P. syringae 6; Provisional


The actual alignment was detected with superfamily member PLN03210:

Pssm-ID: 215633 [Multi-domain]  Cd Length: 1153  Bit Score: 49.87  E-value: 1.16e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256006  455 PTFHELVLSLSKLKKLRVLVIRDCDLIDNIDKLSGLQGLHVLEVSGASSLVNIPDDffknMTQLQSLNLSGLAIKSSPST 534
Cdd:PLN03210  789 PSLVELPSSIQNLHKLEHLEIENCINLETLPTGINLESLESLDLSGCSRLRTFPDI----STNISDLNLSRTGIEEVPWW 864

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 240256006  535 IEKLSMLRCFILRHCSELQDLPNFIVETRKLEVID 569
Cdd:PLN03210  865 IEKFSNLSFLDMNGCNNLQRVSLNISKLKHLETVD 899
 
Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
620-904 1.24e-26

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 114.26  E-value: 1.24e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256006  620 LKDSTNDFSTMPILTRLLLRNCTRLKRLPQLRPLTNLQILDACGATDLVEMLEVCLEEKKELRILDMSKTSLPELADTIA 699
Cdd:COG4886    14 LLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLG 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256006  700 DVVNLNKLLLRNCslieelPSIEKLTHLEVFDVSGCiKLKNINGSFGEMSYLHEVNLSETNLSELPDKISELSNLKELII 779
Cdd:COG4886    94 DLTNLTELDLSGN------EELSNLTNLESLDLSGN-QLTDLPEELANLTNLKELDLSNNQLTDLPEPLGNLTNLKSLDL 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256006  780 RKCsKLKTLPN-LEKLTNLEIFDVSGcTELETIEGSFENLSCLHKVNLSETNLGELPNKISELSNLKELILRNCsKLKAL 858
Cdd:COG4886   167 SNN-QLTDLPEeLGNLTNLKELDLSN-NQITDLPEPLGNLTNLEELDLSGNQLTDLPEPLANLTNLETLDLSNN-QLTDL 243

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*.
gi 240256006  859 PNLEKLTHLVIFDVSGcTNLDKIEESFEsMSYLCEVNLSGTNLKTF 904
Cdd:COG4886   244 PELGNLTNLEELDLSN-NQLTDLPPLAN-LTNLKTLDLSNNQLTDL 287
PLN03210 PLN03210
Resistant to P. syringae 6; Provisional
 638-880 4.81e-17

Resistant to P. syringae 6; Provisional


Pssm-ID: 215633 [Multi-domain]  Cd Length: 1153  Bit Score: 87.24  E-value: 4.81e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256006  638 LRNCTRLKRLPQLRPLTNLQILDACGATDLVEmLEVCLEEKKELRILDMSKTSLPELADTIADVVNLNKLLLRNCS---- 713
Cdd:PLN03210  641 LRGSKNLKEIPDLSMATNLETLKLSDCSSLVE-LPSSIQYLNKLEDLDMSRCENLEILPTGINLKSLYRLNLSGCSrlks 719

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256006  714 ----------------LIEELPS---IEKLTHLEVFDVSGCIKLKNINGSFGEMSY----LHEVNLSET-NLSELPDKIS 769
Cdd:PLN03210  720 fpdistniswldldetAIEEFPSnlrLENLDELILCEMKSEKLWERVQPLTPLMTMlspsLTRLFLSDIpSLVELPSSIQ 799

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256006  770 ELSNLKELIIRKCSKLKTLPNLEKLTNLEIFDVSGCTELETIEGSFENLSCLhkvNLSETNLGELPNKISELSNLKELIL 849
Cdd:PLN03210  800 NLHKLEHLEIENCINLETLPTGINLESLESLDLSGCSRLRTFPDISTNISDL---NLSRTGIEEVPWWIEKFSNLSFLDM 876

                         250       260       270
                  ....*....|....*....|....*....|..
gi 240256006  850 RNCSKLKAL-PNLEKLTHLVIFDVSGCTNLDK 880
Cdd:PLN03210  877 NGCNNLQRVsLNISKLKHLETVDFSDCGALTE 908
NACHT COG5635
Predicted NTPase, NACHT family domain [Signal transduction mechanisms];
27-233 8.76e-09

Predicted NTPase, NACHT family domain [Signal transduction mechanisms];


Pssm-ID: 444362 [Multi-domain]  Cd Length: 935  Bit Score: 59.82  E-value: 8.76e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256006   27 SKTVLVGEAGIGKTWLAKEVSQRVTQEKYN-----VLWLHLnKKIEDEKSLYEILAAQLSIIYEFeegeepdeldyPLES 101
Cdd:COG5635   181 KRLLILGEPGSGKTTLLRYLALELAERYLDaedpiPILIEL-RDLAEEASLEDLLAEALEKRGGE-----------PEDA 248

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256006  102 LKEKIKEemikhkkDNLLLILD--DEGSMTTE-EDVMQELNlqDFLKEYSAVKILVTRR----DEREEKESTTIKVGPLT 174
Cdd:COG5635   249 LERLLRN-------GRLLLLLDglDEVPDEADrDEVLNQLR--RFLERYPKARVIITSRpegyDSSELEGFEVLELAPLS 319

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 240256006  175 EKESLDLLHDAEDLLTSFTSEdwpvLLKRLCDNKEIKE----P---TLMSCILSKSKGLPAAIVVL 233
Cdd:COG5635   320 DEQIEEFLKKWFEATERKAER----LLEALEENPELRElarnPlllTLLALLLRERGELPDTRAEL 381
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 751-898 8.01e-06

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 48.24  E-value: 8.01e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256006  751 LHEVNLSETNLSELPDkISELSNLKELIIRKcSKLKTLPNLEKLTNL-----------EIFDVSGCTELE---------- 809
Cdd:cd21340     4 ITHLYLNDKNITKIDN-LSLCKNLKVLYLYD-NKITKIENLEFLTNLthlylqnnqieKIENLENLVNLKklylggnris 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256006  810 TIEGsFENLSCLHKVNLSETNLGE------LPNKISELSN-LKELILRNCsKLKALPNLEKLTHLVIFDVSGC--TNLDK 880
Cdd:cd21340    82 VVEG-LENLTNLEELHIENQRLPPgekltfDPRSLAALSNsLRVLNISGN-NIDSLEPLAPLRNLEQLDASNNqiSDLEE 159

                         170
                  ....*....|....*...
gi 240256006  881 IEESFESMSYLCEVNLSG 898
Cdd:cd21340   160 LLDLLSSWPSLRELDLTG 177
PLN03210 PLN03210
Resistant to P. syringae 6; Provisional
 455-569 1.16e-05

Resistant to P. syringae 6; Provisional


Pssm-ID: 215633 [Multi-domain]  Cd Length: 1153  Bit Score: 49.87  E-value: 1.16e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256006  455 PTFHELVLSLSKLKKLRVLVIRDCDLIDNIDKLSGLQGLHVLEVSGASSLVNIPDDffknMTQLQSLNLSGLAIKSSPST 534
Cdd:PLN03210  789 PSLVELPSSIQNLHKLEHLEIENCINLETLPTGINLESLESLDLSGCSRLRTFPDI----STNISDLNLSRTGIEEVPWW 864

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 240256006  535 IEKLSMLRCFILRHCSELQDLPNFIVETRKLEVID 569
Cdd:PLN03210  865 IEKFSNLSFLDMNGCNNLQRVSLNISKLKHLETVD 899
NB-ARC pfam00931
NB-ARC domain;
9-285 1.80e-05

NB-ARC domain;


Pssm-ID: 395745 [Multi-domain]  Cd Length: 245  Bit Score: 47.76  E-value: 1.80e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256006     9 REEILKKIMDSLGQDGVPSKTVLVGEAGIGKTWLAKEV---SQRVTQEKYNVLWLHLNKKIEDEKSLYEILAaqlsiiye 85
Cdd:pfam00931    1 REDMVEKVIGKLSEKDEPGIVGIHGMGGVGKTTLAAQIfndFDEVEGHFDSVAWVVVSKTFTISTLQQTILQ-------- 72

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256006    86 FEEGEEPDELDYPLESLKEKIKEEMIKHkkdNLLLILDdegsmtteeDVMQELNLQDFLKEYSAV----KILVTRRDE-- 159
Cdd:pfam00931   73 NLGLSEDDWDNKEEGELARKIRRALLTK---RFLLVLD---------DVWDEEDWDKIGIPLPDRengcRVLLTTRSEev 140

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256006   160 --REEKESTTIKVGPLTEKESLDLlhdaedlltsFTSEDWPvllKRLCDNKEIKEptLMSCILSKSKGLPAAIVVlIKSL 237
Cdd:pfam00931  141 agRVGGPSDPHEVELLEPDEAWEL----------FENKVFP---KTLGECELLED--VAKEIVEKCRGLPLALKV-LGGL 204

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*...
gi 240256006   238 NSIKSMSAKQRKIFKELILSSKSLDEaaaSKNAIDrsrynPVLQLSYE 285
Cdd:pfam00931  205 LSCKKTVEEWKHVYDVLQSELKSNSY---SLNSVR-----SILQLSYE 244
 
Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
620-904 1.24e-26

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 114.26  E-value: 1.24e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256006  620 LKDSTNDFSTMPILTRLLLRNCTRLKRLPQLRPLTNLQILDACGATDLVEMLEVCLEEKKELRILDMSKTSLPELADTIA 699
Cdd:COG4886    14 LLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLG 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256006  700 DVVNLNKLLLRNCslieelPSIEKLTHLEVFDVSGCiKLKNINGSFGEMSYLHEVNLSETNLSELPDKISELSNLKELII 779
Cdd:COG4886    94 DLTNLTELDLSGN------EELSNLTNLESLDLSGN-QLTDLPEELANLTNLKELDLSNNQLTDLPEPLGNLTNLKSLDL 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256006  780 RKCsKLKTLPN-LEKLTNLEIFDVSGcTELETIEGSFENLSCLHKVNLSETNLGELPNKISELSNLKELILRNCsKLKAL 858
Cdd:COG4886   167 SNN-QLTDLPEeLGNLTNLKELDLSN-NQITDLPEPLGNLTNLEELDLSGNQLTDLPEPLANLTNLETLDLSNN-QLTDL 243

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*.
gi 240256006  859 PNLEKLTHLVIFDVSGcTNLDKIEESFEsMSYLCEVNLSGTNLKTF 904
Cdd:COG4886   244 PELGNLTNLEELDLSN-NQLTDLPPLAN-LTNLKTLDLSNNQLTDL 287
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
620-907 5.31e-23

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 103.09  E-value: 5.31e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256006  620 LKDSTNDFSTMPILTRLLLRNCTRLKRLPQLRPLTNLQILDACGATDLVEMlevcleekKELRILDMSKTSLPELADTIA 699
Cdd:COG4886    62 LSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGNEELSNL--------TNLESLDLSGNQLTDLPEELA 133

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256006  700 DVVNLNKLLLRNCSLIEELPSIEKLTHLEVFDVSGCiKLKNINGSFGEMSYLHEVNLSETNLSELPDKISELSNLKELII 779
Cdd:COG4886   134 NLTNLKELDLSNNQLTDLPEPLGNLTNLKSLDLSNN-QLTDLPEELGNLTNLKELDLSNNQITDLPEPLGNLTNLEELDL 212

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256006  780 RKCsKLKTLP-NLEKLTNLEIFDVSGcTELETIEgSFENLSCLHKVNLSETNLGELPnKISELSNLKELILRNCS----K 854
Cdd:COG4886   213 SGN-QLTDLPePLANLTNLETLDLSN-NQLTDLP-ELGNLTNLEELDLSNNQLTDLP-PLANLTNLKTLDLSNNQltdlK 288

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|...
gi 240256006  855 LKALPNLEKLTHLVIFDVSGCTNLDKIEESFESMSYLCEVNLSGTNLKTFPEL 907
Cdd:COG4886   289 LKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLA 341
PLN03210 PLN03210
Resistant to P. syringae 6; Provisional
 638-880 4.81e-17

Resistant to P. syringae 6; Provisional


Pssm-ID: 215633 [Multi-domain]  Cd Length: 1153  Bit Score: 87.24  E-value: 4.81e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256006  638 LRNCTRLKRLPQLRPLTNLQILDACGATDLVEmLEVCLEEKKELRILDMSKTSLPELADTIADVVNLNKLLLRNCS---- 713
Cdd:PLN03210  641 LRGSKNLKEIPDLSMATNLETLKLSDCSSLVE-LPSSIQYLNKLEDLDMSRCENLEILPTGINLKSLYRLNLSGCSrlks 719

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256006  714 ----------------LIEELPS---IEKLTHLEVFDVSGCIKLKNINGSFGEMSY----LHEVNLSET-NLSELPDKIS 769
Cdd:PLN03210  720 fpdistniswldldetAIEEFPSnlrLENLDELILCEMKSEKLWERVQPLTPLMTMlspsLTRLFLSDIpSLVELPSSIQ 799

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256006  770 ELSNLKELIIRKCSKLKTLPNLEKLTNLEIFDVSGCTELETIEGSFENLSCLhkvNLSETNLGELPNKISELSNLKELIL 849
Cdd:PLN03210  800 NLHKLEHLEIENCINLETLPTGINLESLESLDLSGCSRLRTFPDISTNISDL---NLSRTGIEEVPWWIEKFSNLSFLDM 876

                         250       260       270
                  ....*....|....*....|....*....|..
gi 240256006  850 RNCSKLKAL-PNLEKLTHLVIFDVSGCTNLDK 880
Cdd:PLN03210  877 NGCNNLQRVsLNISKLKHLETVDFSDCGALTE 908
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
681-906 2.14e-15

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 79.98  E-value: 2.14e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256006  681 LRILDMSKTSLPELADTIADVVNLNKLLLRNCSLIEELPSIEKLTHLEVFDVSGCIKLKNINGSFGEMSYLHEVNLSETN 760
Cdd:COG4886     5 LLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSL 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256006  761 LSELPDKISELSNLKELIIRKCsklktlPNLEKLTNLEIFDVSGcTELETIEGSFENLSCLHKVNLSETNLGELPNKISE 840
Cdd:COG4886    85 LLLGLTDLGDLTNLTELDLSGN------EELSNLTNLESLDLSG-NQLTDLPEELANLTNLKELDLSNNQLTDLPEPLGN 157

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 240256006  841 LSNLKELILRNCsKLKALPN-LEKLTHLVIFDVSGcTNLDKIEESFESMSYLCEVNLSGTNLKTFPE 906
Cdd:COG4886   158 LTNLKSLDLSNN-QLTDLPEeLGNLTNLKELDLSN-NQITDLPEPLGNLTNLEELDLSGNQLTDLPE 222
PLN03210 PLN03210
Resistant to P. syringae 6; Provisional
 684-905 5.99e-12

Resistant to P. syringae 6; Provisional


Pssm-ID: 215633 [Multi-domain]  Cd Length: 1153  Bit Score: 70.29  E-value: 5.99e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256006  684 LDMSKTSLPELADTIADVVNLNKLLLRNCSLIEELPSIEKLTHLEVFDVSGCIKLKNINGSFGEMSYLHEVNLSE-TNLS 762
Cdd:PLN03210  616 LQMQGSKLEKLWDGVHSLTGLRNIDLRGSKNLKEIPDLSMATNLETLKLSDCSSLVELPSSIQYLNKLEDLDMSRcENLE 695

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256006  763 ELPDKISeLSNLKELIIRKCSKLKTLPNLEklTNLEIFDVSGcTELETIEGS--FENLSCLH------------------ 822
Cdd:PLN03210  696 ILPTGIN-LKSLYRLNLSGCSRLKSFPDIS--TNISWLDLDE-TAIEEFPSNlrLENLDELIlcemkseklwervqpltp 771

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256006  823 ----------KVNLSET-NLGELPNKISELSNLKELILRNCSKLKALPNLEKLTHLVIFDVSGCTNLdkieESFESMSY- 890
Cdd:PLN03210  772 lmtmlspsltRLFLSDIpSLVELPSSIQNLHKLEHLEIENCINLETLPTGINLESLESLDLSGCSRL----RTFPDISTn 847

                         250
                  ....*....|....*
gi 240256006  891 LCEVNLSGTNLKTFP 905
Cdd:PLN03210  848 ISDLNLSRTGIEEVP 862
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
361-771 5.44e-11

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 66.11  E-value: 5.44e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256006  361 NMVVPEFSMSNLLDLQDCGFFGRSSLGFDRVYGGDKRKGLGKIILIDDMIQTIQSKKKNITTIIASGNRLRREVHGKFFE 440
Cdd:COG4886    29 LLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGNEE 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256006  441 KPEMQDLEVVVLFEPTFHELVLSLSKLKKLRVLVIRDCDLIDNIDKLSGLQGLHVLEVSGaSSLVNIPdDFFKNMTQLQS 520
Cdd:COG4886   109 LSNLTNLESLDLSGNQLTDLPEELANLTNLKELDLSNNQLTDLPEPLGNLTNLKSLDLSN-NQLTDLP-EELGNLTNLKE 186

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256006  521 LNLSGLAIKSSPSTIEKLSMLRCFILRHCsELQDLPNFIVETRKLEVIDIHGarklesyfDRVKDWkdykgknKNFAQLQ 600
Cdd:COG4886   187 LDLSNNQITDLPEPLGNLTNLEELDLSGN-QLTDLPEPLANLTNLETLDLSN--------NQLTDL-------PELGNLT 250

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256006  601 LLEHLDFSETKIIRLPifhlkdstnDFSTMPILTRLLLRNC----TRLKRLPQLRPLTNLQILDACGATDLVEMLEvcLE 676
Cdd:COG4886   251 NLEELDLSNNQLTDLP---------PLANLTNLKTLDLSNNqltdLKLKELELLLGLNSLLLLLLLLNLLELLILL--LL 319

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256006  677 EKKELRILDMSKTSLPELADTIADVVNLNKLLLRNCSLIEELPSIEKLTHLEVFDVSGCIKLKNINGSFGEMSYLHEVNL 756
Cdd:COG4886   320 LTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLALLLLTLLLLLLTTTAG 399

                         410
                  ....*....|....*
gi 240256006  757 SETNLSELPDKISEL 771
Cdd:COG4886   400 VLLLTLALLDAVNTE 414
PLN03210 PLN03210
Resistant to P. syringae 6; Provisional
 751-861 1.95e-09

Resistant to P. syringae 6; Provisional


Pssm-ID: 215633 [Multi-domain]  Cd Length: 1153  Bit Score: 62.20  E-value: 1.95e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256006  751 LHEVNLSETNLSELPDKISELSNLKELIIRKCSKLKTLPNLEKLTNLEIFDVSGCTELETIEGSFENLSCLHKVNLSE-T 829
Cdd:PLN03210  613 LVKLQMQGSKLEKLWDGVHSLTGLRNIDLRGSKNLKEIPDLSMATNLETLKLSDCSSLVELPSSIQYLNKLEDLDMSRcE 692

                          90       100       110
                  ....*....|....*....|....*....|..
gi 240256006  830 NLGELPNKISeLSNLKELILRNCSKLKALPNL 861
Cdd:PLN03210  693 NLEILPTGIN-LKSLYRLNLSGCSRLKSFPDI 723
NACHT COG5635
Predicted NTPase, NACHT family domain [Signal transduction mechanisms];
27-233 8.76e-09

Predicted NTPase, NACHT family domain [Signal transduction mechanisms];


Pssm-ID: 444362 [Multi-domain]  Cd Length: 935  Bit Score: 59.82  E-value: 8.76e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256006   27 SKTVLVGEAGIGKTWLAKEVSQRVTQEKYN-----VLWLHLnKKIEDEKSLYEILAAQLSIIYEFeegeepdeldyPLES 101
Cdd:COG5635   181 KRLLILGEPGSGKTTLLRYLALELAERYLDaedpiPILIEL-RDLAEEASLEDLLAEALEKRGGE-----------PEDA 248

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256006  102 LKEKIKEemikhkkDNLLLILD--DEGSMTTE-EDVMQELNlqDFLKEYSAVKILVTRR----DEREEKESTTIKVGPLT 174
Cdd:COG5635   249 LERLLRN-------GRLLLLLDglDEVPDEADrDEVLNQLR--RFLERYPKARVIITSRpegyDSSELEGFEVLELAPLS 319

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 240256006  175 EKESLDLLHDAEDLLTSFTSEdwpvLLKRLCDNKEIKE----P---TLMSCILSKSKGLPAAIVVL 233
Cdd:COG5635   320 DEQIEEFLKKWFEATERKAER----LLEALEENPELRElarnPlllTLLALLLRERGELPDTRAEL 381
PLN03210 PLN03210
Resistant to P. syringae 6; Provisional
 459-822 1.29e-08

Resistant to P. syringae 6; Provisional


Pssm-ID: 215633 [Multi-domain]  Cd Length: 1153  Bit Score: 59.50  E-value: 1.29e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256006  459 ELVLSLSKLKKLRVLV-----IRDCDL-----IDNIDKLSGLQGLHVLEVSGASSLVNIPDDFfKNMTQLQSLNLSG-LA 527
Cdd:PLN03210  615 KLQMQGSKLEKLWDGVhsltgLRNIDLrgsknLKEIPDLSMATNLETLKLSDCSSLVELPSSI-QYLNKLEDLDMSRcEN 693

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256006  528 IKSSPSTIeKLSMLRCFILRHCSELQDLPNFIVETRKLE-----VIDIHGARKLESYFD-RVKDWKDYKGKNKNFAQLQL 601
Cdd:PLN03210  694 LEILPTGI-NLKSLYRLNLSGCSRLKSFPDISTNISWLDldetaIEEFPSNLRLENLDElILCEMKSEKLWERVQPLTPL 772

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256006  602 LEHLDFSETKIIRLPIFHLKDSTNDFSTMPILTRLLLRNCTRLKRLPQLRPLTNLQILDACGATDLVEMLEVcleeKKEL 681
Cdd:PLN03210  773 MTMLSPSLTRLFLSDIPSLVELPSSIQNLHKLEHLEIENCINLETLPTGINLESLESLDLSGCSRLRTFPDI----STNI 848

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256006  682 RILDMSKTSLPELADTIADVVNLNKLLLRNCS-LIEELPSIEKLTHLEVFDVSGCIKLK--NINGSFGEMsylheVNLSE 758
Cdd:PLN03210  849 SDLNLSRTGIEEVPWWIEKFSNLSFLDMNGCNnLQRVSLNISKLKHLETVDFSDCGALTeaSWNGSPSEV-----AMATD 923

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 240256006  759 TNLSELPdkiselSNLKELIIrKCSKLKTLPNLEKLTNLEIFDVSGCTEL-----ETIEGSFENLSCLH 822
Cdd:PLN03210  924 NIHSKLP------STVCINFI-NCFNLDQEALLQQQSIFKQLILSGEEVPsyfthRTTGASLTNIPLLH 985
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 675-849 2.28e-06

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 52.16  E-value: 2.28e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256006  675 LEEKKELRILDMSKTSLP-ELADTIADVVNLNKLLLRNCSLIEELPSieklthlevfDVSGCIKLKNI----NGSFGEMS 749
Cdd:PLN00113  352 LGKHNNLTVLDLSTNNLTgEIPEGLCSSGNLFKLILFSNSLEGEIPK----------SLGACRSLRRVrlqdNSFSGELP 421

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256006  750 -------YLHEVNLSETNLS-ELPDKISELSNLKELIIRKCSKLKTLPNLEKLTNLEIFDVSGCTELETIEGSFENLSCL 821
Cdd:PLN00113  422 seftklpLVYFLDISNNNLQgRINSRKWDMPSLQMLSLARNKFFGGLPDSFGSKRLENLDLSRNQFSGAVPRKLGSLSEL 501

                         170       180
                  ....*....|....*....|....*....
gi 240256006  822 HKVNLSETNL-GELPNKISELSNLKELIL 849
Cdd:PLN00113  502 MQLKLSENKLsGEIPDELSSCKKLVSLDL 530
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 751-898 8.01e-06

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 48.24  E-value: 8.01e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256006  751 LHEVNLSETNLSELPDkISELSNLKELIIRKcSKLKTLPNLEKLTNL-----------EIFDVSGCTELE---------- 809
Cdd:cd21340     4 ITHLYLNDKNITKIDN-LSLCKNLKVLYLYD-NKITKIENLEFLTNLthlylqnnqieKIENLENLVNLKklylggnris 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256006  810 TIEGsFENLSCLHKVNLSETNLGE------LPNKISELSN-LKELILRNCsKLKALPNLEKLTHLVIFDVSGC--TNLDK 880
Cdd:cd21340    82 VVEG-LENLTNLEELHIENQRLPPgekltfDPRSLAALSNsLRVLNISGN-NIDSLEPLAPLRNLEQLDASNNqiSDLEE 159

                         170
                  ....*....|....*...
gi 240256006  881 IEESFESMSYLCEVNLSG 898
Cdd:cd21340   160 LLDLLSSWPSLRELDLTG 177
PLN03210 PLN03210
Resistant to P. syringae 6; Provisional
 455-569 1.16e-05

Resistant to P. syringae 6; Provisional


Pssm-ID: 215633 [Multi-domain]  Cd Length: 1153  Bit Score: 49.87  E-value: 1.16e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256006  455 PTFHELVLSLSKLKKLRVLVIRDCDLIDNIDKLSGLQGLHVLEVSGASSLVNIPDDffknMTQLQSLNLSGLAIKSSPST 534
Cdd:PLN03210  789 PSLVELPSSIQNLHKLEHLEIENCINLETLPTGINLESLESLDLSGCSRLRTFPDI----STNISDLNLSRTGIEEVPWW 864

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 240256006  535 IEKLSMLRCFILRHCSELQDLPNFIVETRKLEVID 569
Cdd:PLN03210  865 IEKFSNLSFLDMNGCNNLQRVSLNISKLKHLETVD 899
NB-ARC pfam00931
NB-ARC domain;
9-285 1.80e-05

NB-ARC domain;


Pssm-ID: 395745 [Multi-domain]  Cd Length: 245  Bit Score: 47.76  E-value: 1.80e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256006     9 REEILKKIMDSLGQDGVPSKTVLVGEAGIGKTWLAKEV---SQRVTQEKYNVLWLHLNKKIEDEKSLYEILAaqlsiiye 85
Cdd:pfam00931    1 REDMVEKVIGKLSEKDEPGIVGIHGMGGVGKTTLAAQIfndFDEVEGHFDSVAWVVVSKTFTISTLQQTILQ-------- 72

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256006    86 FEEGEEPDELDYPLESLKEKIKEEMIKHkkdNLLLILDdegsmtteeDVMQELNLQDFLKEYSAV----KILVTRRDE-- 159
Cdd:pfam00931   73 NLGLSEDDWDNKEEGELARKIRRALLTK---RFLLVLD---------DVWDEEDWDKIGIPLPDRengcRVLLTTRSEev 140

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256006   160 --REEKESTTIKVGPLTEKESLDLlhdaedlltsFTSEDWPvllKRLCDNKEIKEptLMSCILSKSKGLPAAIVVlIKSL 237
Cdd:pfam00931  141 agRVGGPSDPHEVELLEPDEAWEL----------FENKVFP---KTLGECELLED--VAKEIVEKCRGLPLALKV-LGGL 204

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*...
gi 240256006   238 NSIKSMSAKQRKIFKELILSSKSLDEaaaSKNAIDrsrynPVLQLSYE 285
Cdd:pfam00931  205 LSCKKTVEEWKHVYDVLQSELKSNSY---SLNSVR-----SILQLSYE 244
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 681-925 1.59e-04

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 45.99  E-value: 1.59e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256006  681 LRILDMSKTSLP-ELADTIADVVNLNKLLLRNCSLIEELP-SIEKLTHLEVFDVSGCIKLKNINGSFGEMSYLHEVNLSE 758
Cdd:PLN00113  142 LETLDLSNNMLSgEIPNDIGSFSSLKVLDLGGNVLVGKIPnSLTNLTSLEFLTLASNQLVGQIPRELGQMKSLKWIYLGY 221

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256006  759 TNLS-ELPDKISELSNLKEL----------IIRKCSKLKTLP------------------NLEKLTNLEIFDVSGCTELE 809
Cdd:PLN00113  222 NNLSgEIPYEIGGLTSLNHLdlvynnltgpIPSSLGNLKNLQylflyqnklsgpippsifSLQKLISLDLSDNSLSGEIP 301

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256006  810 TIEGSFENLSCLHkvnLSETNL-GELPNKISELSNLKELILRNCSKLKALP-NLEKLTHLVIFDVSGCTNLDKIEESFES 887
Cdd:PLN00113  302 ELVIQLQNLEILH---LFSNNFtGKIPVALTSLPRLQVLQLWSNKFSGEIPkNLGKHNNLTVLDLSTNNLTGEIPEGLCS 378

                         250       260       270
                  ....*....|....*....|....*....|....*....
gi 240256006  888 MSYLCEVNLSGTNLKTfpELPKQSILCSS-KRIVLADSS 925
Cdd:PLN00113  379 SGNLFKLILFSNSLEG--EIPKSLGACRSlRRVRLQDNS 415
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 697-858 1.61e-03

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 41.31  E-value: 1.61e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256006  697 TIADVVNLNKL----LLRNCslIEELPSIEKLTHLEVFDVSG-CI-KLKNINGsfgeMSYLHEVNLSETNLSE------L 764
Cdd:cd21340    38 KIENLEFLTNLthlyLQNNQ--IEKIENLENLVNLKKLYLGGnRIsVVEGLEN----LTNLEELHIENQRLPPgekltfD 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256006  765 PDKISELSN-LKELIIRKCsKLKTLPNLEKLTNLEIFDVSGC--TELETIEGSFENLSCLHKVNLSEtnlgelpNKISEL 841
Cdd:cd21340   112 PRSLAALSNsLRVLNISGN-NIDSLEPLAPLRNLEQLDASNNqiSDLEELLDLLSSWPSLRELDLTG-------NPVCKK 183

                         170
                  ....*....|....*..
gi 240256006  842 SNLKELILRNCSKLKAL 858
Cdd:cd21340   184 PKYRDKIILASKSLEVL 200
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 725-910 4.61e-03

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 41.37  E-value: 4.61e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256006  725 THLEVFDVSGciklKNING----SFGEMSYLHEVNLSETNLS-ELPDKISELsnlkeliirkCSKLKTLpnlekltNLEI 799
Cdd:PLN00113   69 SRVVSIDLSG----KNISGkissAIFRLPYIQTINLSNNQLSgPIPDDIFTT----------SSSLRYL-------NLSN 127

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240256006  800 FDVSGcteleTIEGSFenLSCLHKVNLSETNL-GELPNKISELSNLKELILRNCSKLKALPN-LEKLTHLVIFDVSGCTN 877
Cdd:PLN00113  128 NNFTG-----SIPRGS--IPNLETLDLSNNMLsGEIPNDIGSFSSLKVLDLGGNVLVGKIPNsLTNLTSLEFLTLASNQL 200

                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 240256006  878 LDKIEESFESMS-----YLCEVNLSGtnlktfpELPKQ 910
Cdd:PLN00113  201 VGQIPRELGQMKslkwiYLGYNNLSG-------EIPYE 231
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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