VEFS-Box of polycomb protein [Arabidopsis thaliana]
polycomb protein( domain architecture ID 10560825)
VEFS family polycomb protein such as human polycomb protein SUZ12
List of domain hits
Name | Accession | Description | Interval | E-value | |||
VEFS-Box | pfam09733 | VEFS-Box of polycomb protein; The VEFS-Box (VRN2-EMF2-FIS2-Su(z)12) box is the C-terminal ... |
11-152 | 1.50e-72 | |||
VEFS-Box of polycomb protein; The VEFS-Box (VRN2-EMF2-FIS2-Su(z)12) box is the C-terminal region of these proteins, characterized by an acidic cluster and a tryptophan/methionine-rich sequence, the acidic-W/M domain. Some of these sequences are associated with a zinc-finger domain about 100 residues towards the N-terminus. This protein is one of the polycomb cluster of proteins which control HOX gene transcription as it functions in heterochromatin-mediated repression. : Pssm-ID: 462864 Cd Length: 137 Bit Score: 219.48 E-value: 1.50e-72
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Name | Accession | Description | Interval | E-value | |||
VEFS-Box | pfam09733 | VEFS-Box of polycomb protein; The VEFS-Box (VRN2-EMF2-FIS2-Su(z)12) box is the C-terminal ... |
11-152 | 1.50e-72 | |||
VEFS-Box of polycomb protein; The VEFS-Box (VRN2-EMF2-FIS2-Su(z)12) box is the C-terminal region of these proteins, characterized by an acidic cluster and a tryptophan/methionine-rich sequence, the acidic-W/M domain. Some of these sequences are associated with a zinc-finger domain about 100 residues towards the N-terminus. This protein is one of the polycomb cluster of proteins which control HOX gene transcription as it functions in heterochromatin-mediated repression. Pssm-ID: 462864 Cd Length: 137 Bit Score: 219.48 E-value: 1.50e-72
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VEFS-box_EMF2-like | cd21553 | VEFS (VRN2-EMF2-FIS2-Su(z)12) box found in Arabidopsis thaliana Polycomb group protein ... |
26-153 | 3.66e-56 | |||
VEFS (VRN2-EMF2-FIS2-Su(z)12) box found in Arabidopsis thaliana Polycomb group protein EMBRYONIC FLOWER 2 (EMF2) and similar proteins; This subfamily includes a group of proteins similar to Arabidopsis thaliana Polycomb group (PcG) proteins, EMF2, Polycomb group protein FERTILIZATION-INDEPENDENT SEED 2 (FIS2), and Polycomb group protein VERNALIZATION 2 (VRN2). EMF2 is involved in flowering processes by repressing unknown target genes and preventing reproductive development. It participates in PcG protein complex-mediated (probably in complex with EMF1) silencing of the flower homeotic genes AGAMOUS (AG), PISTILLATA (PI), and APETALA3 (AP3), as well as of some regulatory genes such as ABSCISIC ACID INSENSITIVE3 (ABI3), LONG VEGETATIVE PHASE1 (LOV1), and FLOWERING LOCUS C (FLC) during vegetative development, by mediating trimethylation of histone 3 lysine 27 on the AG chromatin (H3K27me3). FIS2 is required to prevent the proliferation of the central cell by repressing unknown target genes before fertilization. It regulates the anteroposterior organization of the endosperm. VRN2 plays a central role in vernalization by maintaining repressed the homeotic gene FLC, a floral repressor, after cold treatment. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. Members of this family contain a VEFS (VRN2-EMF2-FIS2-Su(z)12) box. Pssm-ID: 439218 Cd Length: 128 Bit Score: 177.52 E-value: 3.66e-56
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Name | Accession | Description | Interval | E-value | |||
VEFS-Box | pfam09733 | VEFS-Box of polycomb protein; The VEFS-Box (VRN2-EMF2-FIS2-Su(z)12) box is the C-terminal ... |
11-152 | 1.50e-72 | |||
VEFS-Box of polycomb protein; The VEFS-Box (VRN2-EMF2-FIS2-Su(z)12) box is the C-terminal region of these proteins, characterized by an acidic cluster and a tryptophan/methionine-rich sequence, the acidic-W/M domain. Some of these sequences are associated with a zinc-finger domain about 100 residues towards the N-terminus. This protein is one of the polycomb cluster of proteins which control HOX gene transcription as it functions in heterochromatin-mediated repression. Pssm-ID: 462864 Cd Length: 137 Bit Score: 219.48 E-value: 1.50e-72
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VEFS-box_EMF2-like | cd21553 | VEFS (VRN2-EMF2-FIS2-Su(z)12) box found in Arabidopsis thaliana Polycomb group protein ... |
26-153 | 3.66e-56 | |||
VEFS (VRN2-EMF2-FIS2-Su(z)12) box found in Arabidopsis thaliana Polycomb group protein EMBRYONIC FLOWER 2 (EMF2) and similar proteins; This subfamily includes a group of proteins similar to Arabidopsis thaliana Polycomb group (PcG) proteins, EMF2, Polycomb group protein FERTILIZATION-INDEPENDENT SEED 2 (FIS2), and Polycomb group protein VERNALIZATION 2 (VRN2). EMF2 is involved in flowering processes by repressing unknown target genes and preventing reproductive development. It participates in PcG protein complex-mediated (probably in complex with EMF1) silencing of the flower homeotic genes AGAMOUS (AG), PISTILLATA (PI), and APETALA3 (AP3), as well as of some regulatory genes such as ABSCISIC ACID INSENSITIVE3 (ABI3), LONG VEGETATIVE PHASE1 (LOV1), and FLOWERING LOCUS C (FLC) during vegetative development, by mediating trimethylation of histone 3 lysine 27 on the AG chromatin (H3K27me3). FIS2 is required to prevent the proliferation of the central cell by repressing unknown target genes before fertilization. It regulates the anteroposterior organization of the endosperm. VRN2 plays a central role in vernalization by maintaining repressed the homeotic gene FLC, a floral repressor, after cold treatment. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. Members of this family contain a VEFS (VRN2-EMF2-FIS2-Su(z)12) box. Pssm-ID: 439218 Cd Length: 128 Bit Score: 177.52 E-value: 3.66e-56
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VEFS-box | cd21521 | VEFS (VRN2-EMF2-FIS2-Su(z)12) box family; This family corresponds to a group of polycomb ... |
29-151 | 1.51e-21 | |||
VEFS (VRN2-EMF2-FIS2-Su(z)12) box family; This family corresponds to a group of polycomb cluster proteins which control HOX gene transcription, as they function in heterochromatin-mediated repression. They are characterized by containing a VEFS-box in the C-terminal region, which is an acidic cluster and a tryptophan/methionine-rich sequence, the acidic-W/M domain. Some of these sequences are associated with a zinc-finger domain about 100 residues towards the N-terminus. Members include suppressor of zeste 12 protein (SUZ12) from vertebrates, plants, insects and fungi, as well as Polycomb group protein EMBRYONIC FLOWER 2 (EMF2), Polycomb group protein FERTILIZATION-INDEPENDENT SEED 2 (FIS2), and Polycomb group protein VERNALIZATION 2 (VRN2) from plants. Pssm-ID: 439215 Cd Length: 121 Bit Score: 87.75 E-value: 1.51e-21
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VEFS-box_SUZ12 | cd21551 | VEFS (VRN2-EMF2-FIS2-Su(z)12) box found in suppressor of zeste 12 protein (SUZ12) and similar ... |
29-149 | 2.69e-09 | |||
VEFS (VRN2-EMF2-FIS2-Su(z)12) box found in suppressor of zeste 12 protein (SUZ12) and similar proteins; SUZ12, also called chromatin precipitated E2F target 9 protein (ChET 9 protein), or joined to JAZF1 protein, is a Polycomb group (PcG) protein that acts as a component of the PRC2/EED-EZH2 complex, which methylates 'Lys-9' (H3K9me) and 'Lys-27' (H3K27me) of histone H3, leading to transcriptional repression of the affected target gene. The PRC2/EED-EZH2 complex may also serve as a recruiting platform for DNA methyltransferases, thereby linking two epigenetic repression systems. This model corresponds to the VEFS (VRN2-EMF2-FIS2-Su(z)12) box at the C-terminus of SUZ12, which is responsible for binding to EED and EZH2. Pssm-ID: 439216 Cd Length: 122 Bit Score: 54.14 E-value: 2.69e-09
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VEFS-box_ctSUZ12-like | cd21552 | VEFS (VRN2-EMF2-FIS2-Su(z)12) box found in Chaetomium thermophilum suppressor of zeste 12 ... |
29-153 | 1.19e-08 | |||
VEFS (VRN2-EMF2-FIS2-Su(z)12) box found in Chaetomium thermophilum suppressor of zeste 12 protein (ctSUZ12) and similar proteins; SUZ12 is a Polycomb group (PcG) protein that acts as a component of the Polycomb Repressive Complex 2 (PRC2), a histone methyltransferase complex composed of core subunits EZH2 (or EZH1), EED, SUZ12 and Rbbp4. PRC2 trimethylates histone H3K27 (H3K27me3) to mark developmentally repressed chromatin. This model corresponds to the VEFS (VRN2-EMF2-FIS2-Su(z)12) box at the C-terminus of SUZ12, which is responsible for binding to EED and EZH2 (or EZH1). Pssm-ID: 439217 Cd Length: 123 Bit Score: 52.56 E-value: 1.19e-08
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Blast search parameters | ||||
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