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Conserved domains on  [gi|15229407|ref|NP_188966|]
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myb domain protein 15 [Arabidopsis thaliana]

Protein Classification

SANT/Myb-like DNA-binding domain-containing protein( domain architecture ID 1000535)

SANT (SWI3, ADA2, N-CoR and TFIIIB)/Myb-like DNA-binding domain-containing protein may be involved in the regulation of gene expression

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PLN03212 super family cl31985
Transcription repressor MYB5; Provisional
 5-191 1.13e-62

Transcription repressor MYB5; Provisional


The actual alignment was detected with superfamily member PLN03212:

Pssm-ID: 178751 [Multi-domain]  Cd Length: 249  Bit Score: 197.99  E-value: 1.13e-62
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15229407    5 PCCEKMGLKRGPWTPEEDQILVSFILNHGHSNWRALPKQAGLLRCGKSCRLRWMNYLKPDIKRGNFTKEEEDAIISLHQI 84
Cdd:PLN03212  16 PCCTKMGMKRGPWTVEEDEILVSFIKKEGEGRWRSLPKRAGLLRCGKSCRLRWMNYLRPSVKRGGITSDEEDLILRLHRL 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15229407   85 LGNRWSAIAAKLPGRTDNEIKNVWHTHLKKRLedyqpakpktsnKKKGTKPKSESVITSSNSTRSESELadssnpSGESL 164
Cdd:PLN03212  96 LGNRWSLIAGRIPGRTDNEIKNYWNTHLRKKL------------LRQGIDPQTHKPLDANNIHKPEEEV------SGGQK 157

                        170       180
                 ....*....|....*....|....*....
gi 15229407  165 FSTSP-STSEVSSMTLISHDGYS-NEINM 191
Cdd:PLN03212 158 YPIEPiSSSHTDDTTVNGGDGDSkNSINV 186
 
Name Accession Description Interval E-value
PLN03212 PLN03212
Transcription repressor MYB5; Provisional
 5-191 1.13e-62

Transcription repressor MYB5; Provisional


Pssm-ID: 178751 [Multi-domain]  Cd Length: 249  Bit Score: 197.99  E-value: 1.13e-62
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15229407    5 PCCEKMGLKRGPWTPEEDQILVSFILNHGHSNWRALPKQAGLLRCGKSCRLRWMNYLKPDIKRGNFTKEEEDAIISLHQI 84
Cdd:PLN03212  16 PCCTKMGMKRGPWTVEEDEILVSFIKKEGEGRWRSLPKRAGLLRCGKSCRLRWMNYLRPSVKRGGITSDEEDLILRLHRL 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15229407   85 LGNRWSAIAAKLPGRTDNEIKNVWHTHLKKRLedyqpakpktsnKKKGTKPKSESVITSSNSTRSESELadssnpSGESL 164
Cdd:PLN03212  96 LGNRWSLIAGRIPGRTDNEIKNYWNTHLRKKL------------LRQGIDPQTHKPLDANNIHKPEEEV------SGGQK 157

                        170       180
                 ....*....|....*....|....*....
gi 15229407  165 FSTSP-STSEVSSMTLISHDGYS-NEINM 191
Cdd:PLN03212 158 YPIEPiSSSHTDDTTVNGGDGDSkNSINV 186
Myb_DNA-binding pfam00249
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 67-112 5.23e-16

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 459731 [Multi-domain]  Cd Length: 46  Bit Score: 70.23  E-value: 5.23e-16
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 15229407    67 RGNFTKEEEDAIISLHQILGNRWSAIAAKLPGRTDNEIKNVWHTHL 112
Cdd:pfam00249   1 RGPWTPEEDELLLEAVEKLGNRWKKIAKLLPGRTDNQCKNRWQNYL 46
REB1 COG5147
Myb superfamily proteins, including transcription factors and mRNA splicing factors ...
 12-129 1.01e-14

Myb superfamily proteins, including transcription factors and mRNA splicing factors [Transcription / RNA processing and modification / Cell division and chromosome partitioning];


Pssm-ID: 227476 [Multi-domain]  Cd Length: 512  Bit Score: 73.67  E-value: 1.01e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15229407  12 LKRGPWTPEEDQILVSFILNHGHSNWRALPKQAGLlRCGKSCRLRWMNYLKPDIKRGNFTKEEEDAIISLHQILGNRWSA 91
Cdd:COG5147  18 RKGGSWKRTEDEDLKALVKKLGPNNWSKVASLLIS-STGKQSSNRWNNHLNPQLKKKNWSEEEDEQLIDLDKELGTQWST 96

                        90       100       110
                ....*....|....*....|....*....|....*...
gi 15229407  92 IAAKLPGRTDNEIKNVWhTHLKKRLEDYQPAKPKTSNK 129
Cdd:COG5147  97 IADYKDRRTAQQCVERY-VNTLEDLSSTHDSKLQRRNE 133
SANT smart00717
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;
67-114 4.14e-11

SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;


Pssm-ID: 197842 [Multi-domain]  Cd Length: 49  Bit Score: 56.85  E-value: 4.14e-11
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 15229407     67 RGNFTKEEEDAIISLHQILG-NRWSAIAAKLPGRTDNEIKNVWHTHLKK 114
Cdd:smart00717   1 KGEWTEEEDELLIELVKKYGkNNWEKIAKELPGRTAEQCRERWRNLLKP 49
SANT cd00167
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ...
 69-112 1.70e-10

'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.


Pssm-ID: 238096 [Multi-domain]  Cd Length: 45  Bit Score: 55.27  E-value: 1.70e-10
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....*
gi 15229407  69 NFTKEEEDAIISLHQILG-NRWSAIAAKLPGRTDNEIKNVWHTHL 112
Cdd:cd00167   1 PWTEEEDELLLEAVKKYGkNNWEKIAKELPGRTPKQCRERWRNLL 45
 
Name Accession Description Interval E-value
PLN03212 PLN03212
Transcription repressor MYB5; Provisional
 5-191 1.13e-62

Transcription repressor MYB5; Provisional


Pssm-ID: 178751 [Multi-domain]  Cd Length: 249  Bit Score: 197.99  E-value: 1.13e-62
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15229407    5 PCCEKMGLKRGPWTPEEDQILVSFILNHGHSNWRALPKQAGLLRCGKSCRLRWMNYLKPDIKRGNFTKEEEDAIISLHQI 84
Cdd:PLN03212  16 PCCTKMGMKRGPWTVEEDEILVSFIKKEGEGRWRSLPKRAGLLRCGKSCRLRWMNYLRPSVKRGGITSDEEDLILRLHRL 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15229407   85 LGNRWSAIAAKLPGRTDNEIKNVWHTHLKKRLedyqpakpktsnKKKGTKPKSESVITSSNSTRSESELadssnpSGESL 164
Cdd:PLN03212  96 LGNRWSLIAGRIPGRTDNEIKNYWNTHLRKKL------------LRQGIDPQTHKPLDANNIHKPEEEV------SGGQK 157

                        170       180
                 ....*....|....*....|....*....
gi 15229407  165 FSTSP-STSEVSSMTLISHDGYS-NEINM 191
Cdd:PLN03212 158 YPIEPiSSSHTDDTTVNGGDGDSkNSINV 186
PLN03091 PLN03091
hypothetical protein; Provisional
 1-195 3.01e-61

hypothetical protein; Provisional


Pssm-ID: 215570 [Multi-domain]  Cd Length: 459  Bit Score: 200.59  E-value: 3.01e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15229407    1 MGRAPCCEKMGLKRGPWTPEEDQILVSFILNHGHSNWRALPKQAGLLRCGKSCRLRWMNYLKPDIKRGNFTKEEEDAIIS 80
Cdd:PLN03091   1 MGRHSCCYKQKLRKGLWSPEEDEKLLRHITKYGHGCWSSVPKQAGLQRCGKSCRLRWINYLRPDLKRGTFSQQEENLIIE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15229407   81 LHQILGNRWSAIAAKLPGRTDNEIKNVWHTHLKKRL-------------------EDYQPAKPKTSNKKKGTKPKSESVI 141
Cdd:PLN03091  81 LHAVLGNRWSQIAAQLPGRTDNEIKNLWNSCLKKKLrqrgidpnthkplsevengEDKNPPTDDKSDKASSVVSNELNLL 160

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 15229407  142 TSSNSTRSESELADSSNPSGESLFSTSPSTSEvSSMTLISHDGYSNEINMDNKP 195
Cdd:PLN03091 161 KADNSKPLAALQEKRSSSISPAGYQLEVESSS-SSKINNSNNNNHSNSNLMTPT 213
Myb_DNA-binding pfam00249
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 67-112 5.23e-16

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 459731 [Multi-domain]  Cd Length: 46  Bit Score: 70.23  E-value: 5.23e-16
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 15229407    67 RGNFTKEEEDAIISLHQILGNRWSAIAAKLPGRTDNEIKNVWHTHL 112
Cdd:pfam00249   1 RGPWTPEEDELLLEAVEKLGNRWKKIAKLLPGRTDNQCKNRWQNYL 46
REB1 COG5147
Myb superfamily proteins, including transcription factors and mRNA splicing factors ...
 12-129 1.01e-14

Myb superfamily proteins, including transcription factors and mRNA splicing factors [Transcription / RNA processing and modification / Cell division and chromosome partitioning];


Pssm-ID: 227476 [Multi-domain]  Cd Length: 512  Bit Score: 73.67  E-value: 1.01e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15229407  12 LKRGPWTPEEDQILVSFILNHGHSNWRALPKQAGLlRCGKSCRLRWMNYLKPDIKRGNFTKEEEDAIISLHQILGNRWSA 91
Cdd:COG5147  18 RKGGSWKRTEDEDLKALVKKLGPNNWSKVASLLIS-STGKQSSNRWNNHLNPQLKKKNWSEEEDEQLIDLDKELGTQWST 96

                        90       100       110
                ....*....|....*....|....*....|....*...
gi 15229407  92 IAAKLPGRTDNEIKNVWhTHLKKRLEDYQPAKPKTSNK 129
Cdd:COG5147  97 IADYKDRRTAQQCVERY-VNTLEDLSSTHDSKLQRRNE 133
Myb_DNA-binding pfam00249
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 14-61 1.04e-12

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 459731 [Multi-domain]  Cd Length: 46  Bit Score: 61.37  E-value: 1.04e-12
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 15229407    14 RGPWTPEEDQILVSFILNHGHsNWRALPKQAGlLRCGKSCRLRWMNYL 61
Cdd:pfam00249   1 RGPWTPEEDELLLEAVEKLGN-RWKKIAKLLP-GRTDNQCKNRWQNYL 46
Myb_DNA-bind_6 pfam13921
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 17-75 2.96e-11

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 372817 [Multi-domain]  Cd Length: 60  Bit Score: 57.71  E-value: 2.96e-11
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 15229407    17 WTPEEDQILVSFILNHGhSNWRALPKQAGLlRCGKSCRLRWMNYLKPDIKRGNFTKEEE 75
Cdd:pfam13921   1 WTEEEDEKLLKLVEKYG-NDWKQIAKELGR-RTPKQCFDRWRRKLNPKISRGPWSKEED 57
SANT smart00717
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;
67-114 4.14e-11

SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;


Pssm-ID: 197842 [Multi-domain]  Cd Length: 49  Bit Score: 56.85  E-value: 4.14e-11
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 15229407     67 RGNFTKEEEDAIISLHQILG-NRWSAIAAKLPGRTDNEIKNVWHTHLKK 114
Cdd:smart00717   1 KGEWTEEEDELLIELVKKYGkNNWEKIAKELPGRTAEQCRERWRNLLKP 49
SANT cd00167
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ...
 69-112 1.70e-10

'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.


Pssm-ID: 238096 [Multi-domain]  Cd Length: 45  Bit Score: 55.27  E-value: 1.70e-10
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....*
gi 15229407  69 NFTKEEEDAIISLHQILG-NRWSAIAAKLPGRTDNEIKNVWHTHL 112
Cdd:cd00167   1 PWTEEEDELLLEAVKKYGkNNWEKIAKELPGRTPKQCRERWRNLL 45
SANT smart00717
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;
14-63 9.53e-10

SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;


Pssm-ID: 197842 [Multi-domain]  Cd Length: 49  Bit Score: 53.38  E-value: 9.53e-10
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 15229407     14 RGPWTPEEDQILVSFILNHGHSNWRALPKQAGlLRCGKSCRLRWMNYLKP 63
Cdd:smart00717   1 KGEWTEEEDELLIELVKKYGKNNWEKIAKELP-GRTAEQCRERWRNLLKP 49
SANT cd00167
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ...
 16-61 3.11e-09

'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.


Pssm-ID: 238096 [Multi-domain]  Cd Length: 45  Bit Score: 51.81  E-value: 3.11e-09
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....*.
gi 15229407  16 PWTPEEDQILVSFILNHGHSNWRALPKQAGlLRCGKSCRLRWMNYL 61
Cdd:cd00167   1 PWTEEEDELLLEAVKKYGKNNWEKIAKELP-GRTPKQCRERWRNLL 45
Myb_DNA-bind_6 pfam13921
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 70-113 1.72e-05

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 372817 [Multi-domain]  Cd Length: 60  Bit Score: 41.53  E-value: 1.72e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 15229407    70 FTKEEEDAIISLHQILGNRWSAIAAKLPGRTDNEIKNVWHTHLK 113
Cdd:pfam13921   1 WTEEEDEKLLKLVEKYGNDWKQIAKELGRRTPKQCFDRWRRKLN 44
SANT_CDC5_II cd11659
SANT/myb-like DNA-binding domain of Cell Division Cycle 5-Like Protein repeat II; In humans, ...
 63-102 3.69e-05

SANT/myb-like DNA-binding domain of Cell Division Cycle 5-Like Protein repeat II; In humans, cell division cycle 5-like protein (CDC5) functions in pre-mRNA splicing in cell cycle control. The DNA-binding, myb-like domain of CDC5 is a member of the SANT/myb group. SANT is named after 'SWI3, ADA2, N-CoR and TFIIIB', several factors that share this domain. The SANT domain resembles the 3 alpha-helix bundle of DNA-binding Myb domains and is found in a diverse set of proteins.


Pssm-ID: 212557 [Multi-domain]  Cd Length: 53  Bit Score: 40.37  E-value: 3.69e-05
                        10        20        30        40
                ....*....|....*....|....*....|....*....|
gi 15229407  63 PDIKRGNFTKEEEDAIISLHQILGNRWSAIaAKLPGRTDN 102
Cdd:cd11659   1 PSIKKTEWTREEDEKLLHLAKLLPTQWRTI-APIVGRTAQ 39
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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