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Conserved domains on  [gi|15228214|ref|NP_188265|]
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myrosinase-binding protein-like protein-300B [Arabidopsis thaliana]

Protein Classification

Kelch domain-containing protein( domain architecture ID 13287143)

Kelch domain-containing protein is a protein that contains one or more kelch domains which play a role in a variety of cellular processes, including cell signaling, transcription regulation, and protein degradation.

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Jacalin pfam01419
Jacalin-like lectin domain; Proteins containing this domain are lectins. It is found in 1 to 6 ...
 165-297 1.24e-60

Jacalin-like lectin domain; Proteins containing this domain are lectins. It is found in 1 to 6 copies in these proteins. The domain is also found in the animal prostatic spermine-binding protein.


:

Pssm-ID: 396138 [Multi-domain]  Cd Length: 134  Bit Score: 189.02  E-value: 1.24e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15228214   165 GTAWDDGAFDGVKKVYIGQAQDGISAVKFVYDKGAEDIVGDEHGNDTLLGFEEFQLDYPSEYITAVEGTYDKIFGFETEV 244
Cdd:pfam01419   1 GASWDDGVYDGVRKVYVGQGGDGITYIKFEYVKGGGKVEGDEHGKKGLLGPEEFEIDYPDEYITSVEGTYDKVFGSDSEV 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 15228214   245 INMLRFKTNK-KTSPPFGIEAGTAFELKEEGCKIVGFHGKVSAVLHQFGVHILP 297
Cdd:pfam01419  81 ITSLTFKTNKgRTSPFFGTPSGTKFSLEVKGKKIVGFHGRAGNALNALGAYFAP 134
PLN02193 super family cl31837
nitrile-specifier protein
 1-143 1.76e-54

nitrile-specifier protein


The actual alignment was detected with superfamily member PLN02193:

Pssm-ID: 177844 [Multi-domain]  Cd Length: 470  Bit Score: 183.62  E-value: 1.76e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15228214    1 MAQKVEAQGGIGGDVWDDGAHDGVRKVHVGQGLDGVSFINVVYENGSQEVVGGEHGKKSLIGIETFEVDADDYIVAVQVT 80
Cdd:PLN02193   1 MAQKLEAKGGETGDVWDDGVYDNVRKVYVGQGQYGIAFVKFEYVNGSQVVVGDEHGKKTELGVEEFEIDADDYIVYVEGY 80

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 15228214   81 YDKIFGYDSDIITSITFSTFKGKTSPPYGLDTENKFVLKeknGGKLVGFHGRAGEILYALGAY 143
Cdd:PLN02193  81 REKVNDMTSEMITFLSFKTYKGKTSHPIEKRPGVKFVLQ---GGKIVGFHGRSTDVLHSLGAY 140
 
Name Accession Description Interval E-value
Jacalin pfam01419
Jacalin-like lectin domain; Proteins containing this domain are lectins. It is found in 1 to 6 ...
 165-297 1.24e-60

Jacalin-like lectin domain; Proteins containing this domain are lectins. It is found in 1 to 6 copies in these proteins. The domain is also found in the animal prostatic spermine-binding protein.


Pssm-ID: 396138 [Multi-domain]  Cd Length: 134  Bit Score: 189.02  E-value: 1.24e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15228214   165 GTAWDDGAFDGVKKVYIGQAQDGISAVKFVYDKGAEDIVGDEHGNDTLLGFEEFQLDYPSEYITAVEGTYDKIFGFETEV 244
Cdd:pfam01419   1 GASWDDGVYDGVRKVYVGQGGDGITYIKFEYVKGGGKVEGDEHGKKGLLGPEEFEIDYPDEYITSVEGTYDKVFGSDSEV 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 15228214   245 INMLRFKTNK-KTSPPFGIEAGTAFELKEEGCKIVGFHGKVSAVLHQFGVHILP 297
Cdd:pfam01419  81 ITSLTFKTNKgRTSPFFGTPSGTKFSLEVKGKKIVGFHGRAGNALNALGAYFAP 134
PLN02193 PLN02193
nitrile-specifier protein
 1-143 1.76e-54

nitrile-specifier protein


Pssm-ID: 177844 [Multi-domain]  Cd Length: 470  Bit Score: 183.62  E-value: 1.76e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15228214    1 MAQKVEAQGGIGGDVWDDGAHDGVRKVHVGQGLDGVSFINVVYENGSQEVVGGEHGKKSLIGIETFEVDADDYIVAVQVT 80
Cdd:PLN02193   1 MAQKLEAKGGETGDVWDDGVYDNVRKVYVGQGQYGIAFVKFEYVNGSQVVVGDEHGKKTELGVEEFEIDADDYIVYVEGY 80

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 15228214   81 YDKIFGYDSDIITSITFSTFKGKTSPPYGLDTENKFVLKeknGGKLVGFHGRAGEILYALGAY 143
Cdd:PLN02193  81 REKVNDMTSEMITFLSFKTYKGKTSHPIEKRPGVKFVLQ---GGKIVGFHGRSTDVLHSLGAY 140
Jacalin pfam01419
Jacalin-like lectin domain; Proteins containing this domain are lectins. It is found in 1 to 6 ...
 13-144 2.52e-53

Jacalin-like lectin domain; Proteins containing this domain are lectins. It is found in 1 to 6 copies in these proteins. The domain is also found in the animal prostatic spermine-binding protein.


Pssm-ID: 396138 [Multi-domain]  Cd Length: 134  Bit Score: 170.54  E-value: 2.52e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15228214    13 GDVWDDGAHDGVRKVHVGQGLDGVSFINVVYENGSQEVVGGEHGKKSLIGIETFEVD-ADDYIVAVQVTYDKIFGYDSDI 91
Cdd:pfam01419   1 GASWDDGVYDGVRKVYVGQGGDGITYIKFEYVKGGGKVEGDEHGKKGLLGPEEFEIDyPDEYITSVEGTYDKVFGSDSEV 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 15228214    92 ITSITFSTFKGKTSPPYGLDTENKFVLKEKnGGKLVGFHGRAGEILYALGAYF 144
Cdd:pfam01419  81 ITSLTFKTNKGRTSPFFGTPSGTKFSLEVK-GKKIVGFHGRAGNALNALGAYF 132
Jacalin cd09612
Jacalin-like plant lectin domain; Jacalin-like lectins are sugar-binding protein domains ...
 165-295 1.08e-46

Jacalin-like plant lectin domain; Jacalin-like lectins are sugar-binding protein domains mostly found in plants. They adopt a beta-prism topology consistent with a circularly permuted three-fold repeat of a structural motif. Proteins containing this domain may bind mono- or oligosaccharides with high specificity. The domain can occur in tandem-repeat arrangements with up to six copies, and in architectures combined with a variety of other functional domains. The family was initially named after an abundant protein found in the jackfruit seed. Jacalin specifically binds to the alpha-O-glycoside of the disaccharide Gal-beta1-3-GalNAc, and has proven useful in the study of O-linked glycoproteins. Jacalin-like lectins in this family may occur in various oligomerization states.


Pssm-ID: 187708 [Multi-domain]  Cd Length: 130  Bit Score: 153.49  E-value: 1.08e-46
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15228214 165 GTAWDDGAF-DGVKKVYIGQAQDGISAVKFVYDKGAEDIVGDEHGNDTLlGFEEFQLDYPSEYITAVEGTYDKIFGFEte 243
Cdd:cd09612   1 GSAWDDGVFpDGLRKITVRSGENGIDSIKFEYDKDGQHVVGPWHGGGGG-TPEEIVLDYPDEYITSVSGTYGPVSGSN-- 77

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|..
gi 15228214 244 VINMLRFKTNKKTSPPFGIEAGTAFELKEEGCKIVGFHGKVSAVLHQFGVHI 295
Cdd:cd09612  78 VITSLTFKTNKRTYGPFGVESGTPFSLPVEGGKIVGFHGRSGDYLDAIGVYV 129
PLN02193 PLN02193
nitrile-specifier protein
 154-299 3.42e-44

nitrile-specifier protein


Pssm-ID: 177844 [Multi-domain]  Cd Length: 470  Bit Score: 156.65  E-value: 3.42e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15228214  154 AKKLPAVGGDEGTAWDDGAFDGVKKVYIGQAQDGISAVKFVYDKGAEDIVGDEHGNDTLLGFEEFQLDyPSEYITAVEGT 233
Cdd:PLN02193   2 AQKLEAKGGETGDVWDDGVYDNVRKVYVGQGQYGIAFVKFEYVNGSQVVVGDEHGKKTELGVEEFEID-ADDYIVYVEGY 80

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 15228214  234 YDKIFGFETEVINMLRFKTNK-KTSPPFGIEAGTAFELkeEGCKIVGFHGKVSAVLHQFGVHI-LPVT 299
Cdd:PLN02193  81 REKVNDMTSEMITFLSFKTYKgKTSHPIEKRPGVKFVL--QGGKIVGFHGRSTDVLHSLGAYIsLPST 146
Jacalin smart00915
Jacalin-like lectin domain; This entry represents a mannose-binding lectin domain with a ...
 165-297 1.60e-43

Jacalin-like lectin domain; This entry represents a mannose-binding lectin domain with a beta-prism fold consisting of three 4-stranded beta-sheets, with an internal pseudo 3-fold symmetry. Some lectins in this group stimulate distinct T- and B- cell functions, such as Jacalin, which binds to the T-antigen and acts as an agglutinin. This domain is found in 1 to 6 copies in lectins. The domain is also found in the salt-stress induced protein from rice and an animal prostatic spermine-binding protein.


Pssm-ID: 214909 [Multi-domain]  Cd Length: 128  Bit Score: 145.06  E-value: 1.60e-43
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15228214    165 GTAWDDGAFDGVKKVYIGQAQDGISAVKFVYDKGAeDIVGDEHGNDTLLGFEEfqLDYPSEYITAVEGTYDKifgfeTEV 244
Cdd:smart00915   1 GTEWDDGAFDGVRKIYVGQGGEGIKSIQFDYDKGG-KVWGDEHGGKGGTGEEI--LLYPGEYITSVEGTYDK-----SGV 72

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 15228214    245 INMLRFKTNK-KTSPPFGIEAGTAFELKEEGC-KIVGFHGKVS-AVLHQFGVHILP 297
Cdd:smart00915  73 ITSLTFKTNKgRTSPFGGYEGGTKFVLESKEGkKIVGFHGRSSgDGLDSLGAYFSP 128
Jacalin smart00915
Jacalin-like lectin domain; This entry represents a mannose-binding lectin domain with a ...
 13-144 7.15e-42

Jacalin-like lectin domain; This entry represents a mannose-binding lectin domain with a beta-prism fold consisting of three 4-stranded beta-sheets, with an internal pseudo 3-fold symmetry. Some lectins in this group stimulate distinct T- and B- cell functions, such as Jacalin, which binds to the T-antigen and acts as an agglutinin. This domain is found in 1 to 6 copies in lectins. The domain is also found in the salt-stress induced protein from rice and an animal prostatic spermine-binding protein.


Pssm-ID: 214909 [Multi-domain]  Cd Length: 128  Bit Score: 140.83  E-value: 7.15e-42
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15228214     13 GDVWDDGAHDGVRKVHVGQGLDGVSFINVVYENGsQEVVGGEHGKKSLIGIEtFEVDADDYIVAVQVTYDKifgydSDII 92
Cdd:smart00915   1 GTEWDDGAFDGVRKIYVGQGGEGIKSIQFDYDKG-GKVWGDEHGGKGGTGEE-ILLYPGEYITSVEGTYDK-----SGVI 73

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|...
gi 15228214     93 TSITFSTFKGKTSPPYGLDTENKFVLKEKNGGKLVGFHGR-AGEILYALGAYF 144
Cdd:smart00915  74 TSLTFKTNKGRTSPFGGYEGGTKFVLESKEGKKIVGFHGRsSGDGLDSLGAYF 126
Jacalin cd09612
Jacalin-like plant lectin domain; Jacalin-like lectins are sugar-binding protein domains ...
 13-144 7.10e-38

Jacalin-like plant lectin domain; Jacalin-like lectins are sugar-binding protein domains mostly found in plants. They adopt a beta-prism topology consistent with a circularly permuted three-fold repeat of a structural motif. Proteins containing this domain may bind mono- or oligosaccharides with high specificity. The domain can occur in tandem-repeat arrangements with up to six copies, and in architectures combined with a variety of other functional domains. The family was initially named after an abundant protein found in the jackfruit seed. Jacalin specifically binds to the alpha-O-glycoside of the disaccharide Gal-beta1-3-GalNAc, and has proven useful in the study of O-linked glycoproteins. Jacalin-like lectins in this family may occur in various oligomerization states.


Pssm-ID: 187708 [Multi-domain]  Cd Length: 130  Bit Score: 130.76  E-value: 7.10e-38
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15228214  13 GDVWDDGAH-DGVRKVHVGQGLDGVSFINVVYENGSQEVVGGEHGKKSLiGIETFEVDA-DDYIVAVQVTYDKIFGydSD 90
Cdd:cd09612   1 GSAWDDGVFpDGLRKITVRSGENGIDSIKFEYDKDGQHVVGPWHGGGGG-TPEEIVLDYpDEYITSVSGTYGPVSG--SN 77

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....
gi 15228214  91 IITSITFSTFKgKTSPPYGLDTENKFVLkEKNGGKLVGFHGRAGEILYALGAYF 144
Cdd:cd09612  78 VITSLTFKTNK-RTYGPFGVESGTPFSL-PVEGGKIVGFHGRSGDYLDAIGVYV 129
 
Name Accession Description Interval E-value
Jacalin pfam01419
Jacalin-like lectin domain; Proteins containing this domain are lectins. It is found in 1 to 6 ...
 165-297 1.24e-60

Jacalin-like lectin domain; Proteins containing this domain are lectins. It is found in 1 to 6 copies in these proteins. The domain is also found in the animal prostatic spermine-binding protein.


Pssm-ID: 396138 [Multi-domain]  Cd Length: 134  Bit Score: 189.02  E-value: 1.24e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15228214   165 GTAWDDGAFDGVKKVYIGQAQDGISAVKFVYDKGAEDIVGDEHGNDTLLGFEEFQLDYPSEYITAVEGTYDKIFGFETEV 244
Cdd:pfam01419   1 GASWDDGVYDGVRKVYVGQGGDGITYIKFEYVKGGGKVEGDEHGKKGLLGPEEFEIDYPDEYITSVEGTYDKVFGSDSEV 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 15228214   245 INMLRFKTNK-KTSPPFGIEAGTAFELKEEGCKIVGFHGKVSAVLHQFGVHILP 297
Cdd:pfam01419  81 ITSLTFKTNKgRTSPFFGTPSGTKFSLEVKGKKIVGFHGRAGNALNALGAYFAP 134
PLN02193 PLN02193
nitrile-specifier protein
 1-143 1.76e-54

nitrile-specifier protein


Pssm-ID: 177844 [Multi-domain]  Cd Length: 470  Bit Score: 183.62  E-value: 1.76e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15228214    1 MAQKVEAQGGIGGDVWDDGAHDGVRKVHVGQGLDGVSFINVVYENGSQEVVGGEHGKKSLIGIETFEVDADDYIVAVQVT 80
Cdd:PLN02193   1 MAQKLEAKGGETGDVWDDGVYDNVRKVYVGQGQYGIAFVKFEYVNGSQVVVGDEHGKKTELGVEEFEIDADDYIVYVEGY 80

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 15228214   81 YDKIFGYDSDIITSITFSTFKGKTSPPYGLDTENKFVLKeknGGKLVGFHGRAGEILYALGAY 143
Cdd:PLN02193  81 REKVNDMTSEMITFLSFKTYKGKTSHPIEKRPGVKFVLQ---GGKIVGFHGRSTDVLHSLGAY 140
Jacalin pfam01419
Jacalin-like lectin domain; Proteins containing this domain are lectins. It is found in 1 to 6 ...
 13-144 2.52e-53

Jacalin-like lectin domain; Proteins containing this domain are lectins. It is found in 1 to 6 copies in these proteins. The domain is also found in the animal prostatic spermine-binding protein.


Pssm-ID: 396138 [Multi-domain]  Cd Length: 134  Bit Score: 170.54  E-value: 2.52e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15228214    13 GDVWDDGAHDGVRKVHVGQGLDGVSFINVVYENGSQEVVGGEHGKKSLIGIETFEVD-ADDYIVAVQVTYDKIFGYDSDI 91
Cdd:pfam01419   1 GASWDDGVYDGVRKVYVGQGGDGITYIKFEYVKGGGKVEGDEHGKKGLLGPEEFEIDyPDEYITSVEGTYDKVFGSDSEV 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 15228214    92 ITSITFSTFKGKTSPPYGLDTENKFVLKEKnGGKLVGFHGRAGEILYALGAYF 144
Cdd:pfam01419  81 ITSLTFKTNKGRTSPFFGTPSGTKFSLEVK-GKKIVGFHGRAGNALNALGAYF 132
Jacalin cd09612
Jacalin-like plant lectin domain; Jacalin-like lectins are sugar-binding protein domains ...
 165-295 1.08e-46

Jacalin-like plant lectin domain; Jacalin-like lectins are sugar-binding protein domains mostly found in plants. They adopt a beta-prism topology consistent with a circularly permuted three-fold repeat of a structural motif. Proteins containing this domain may bind mono- or oligosaccharides with high specificity. The domain can occur in tandem-repeat arrangements with up to six copies, and in architectures combined with a variety of other functional domains. The family was initially named after an abundant protein found in the jackfruit seed. Jacalin specifically binds to the alpha-O-glycoside of the disaccharide Gal-beta1-3-GalNAc, and has proven useful in the study of O-linked glycoproteins. Jacalin-like lectins in this family may occur in various oligomerization states.


Pssm-ID: 187708 [Multi-domain]  Cd Length: 130  Bit Score: 153.49  E-value: 1.08e-46
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15228214 165 GTAWDDGAF-DGVKKVYIGQAQDGISAVKFVYDKGAEDIVGDEHGNDTLlGFEEFQLDYPSEYITAVEGTYDKIFGFEte 243
Cdd:cd09612   1 GSAWDDGVFpDGLRKITVRSGENGIDSIKFEYDKDGQHVVGPWHGGGGG-TPEEIVLDYPDEYITSVSGTYGPVSGSN-- 77

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|..
gi 15228214 244 VINMLRFKTNKKTSPPFGIEAGTAFELKEEGCKIVGFHGKVSAVLHQFGVHI 295
Cdd:cd09612  78 VITSLTFKTNKRTYGPFGVESGTPFSLPVEGGKIVGFHGRSGDYLDAIGVYV 129
PLN02193 PLN02193
nitrile-specifier protein
 154-299 3.42e-44

nitrile-specifier protein


Pssm-ID: 177844 [Multi-domain]  Cd Length: 470  Bit Score: 156.65  E-value: 3.42e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15228214  154 AKKLPAVGGDEGTAWDDGAFDGVKKVYIGQAQDGISAVKFVYDKGAEDIVGDEHGNDTLLGFEEFQLDyPSEYITAVEGT 233
Cdd:PLN02193   2 AQKLEAKGGETGDVWDDGVYDNVRKVYVGQGQYGIAFVKFEYVNGSQVVVGDEHGKKTELGVEEFEID-ADDYIVYVEGY 80

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 15228214  234 YDKIFGFETEVINMLRFKTNK-KTSPPFGIEAGTAFELkeEGCKIVGFHGKVSAVLHQFGVHI-LPVT 299
Cdd:PLN02193  81 REKVNDMTSEMITFLSFKTYKgKTSHPIEKRPGVKFVL--QGGKIVGFHGRSTDVLHSLGAYIsLPST 146
Jacalin smart00915
Jacalin-like lectin domain; This entry represents a mannose-binding lectin domain with a ...
 165-297 1.60e-43

Jacalin-like lectin domain; This entry represents a mannose-binding lectin domain with a beta-prism fold consisting of three 4-stranded beta-sheets, with an internal pseudo 3-fold symmetry. Some lectins in this group stimulate distinct T- and B- cell functions, such as Jacalin, which binds to the T-antigen and acts as an agglutinin. This domain is found in 1 to 6 copies in lectins. The domain is also found in the salt-stress induced protein from rice and an animal prostatic spermine-binding protein.


Pssm-ID: 214909 [Multi-domain]  Cd Length: 128  Bit Score: 145.06  E-value: 1.60e-43
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15228214    165 GTAWDDGAFDGVKKVYIGQAQDGISAVKFVYDKGAeDIVGDEHGNDTLLGFEEfqLDYPSEYITAVEGTYDKifgfeTEV 244
Cdd:smart00915   1 GTEWDDGAFDGVRKIYVGQGGEGIKSIQFDYDKGG-KVWGDEHGGKGGTGEEI--LLYPGEYITSVEGTYDK-----SGV 72

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 15228214    245 INMLRFKTNK-KTSPPFGIEAGTAFELKEEGC-KIVGFHGKVS-AVLHQFGVHILP 297
Cdd:smart00915  73 ITSLTFKTNKgRTSPFGGYEGGTKFVLESKEGkKIVGFHGRSSgDGLDSLGAYFSP 128
Jacalin smart00915
Jacalin-like lectin domain; This entry represents a mannose-binding lectin domain with a ...
 13-144 7.15e-42

Jacalin-like lectin domain; This entry represents a mannose-binding lectin domain with a beta-prism fold consisting of three 4-stranded beta-sheets, with an internal pseudo 3-fold symmetry. Some lectins in this group stimulate distinct T- and B- cell functions, such as Jacalin, which binds to the T-antigen and acts as an agglutinin. This domain is found in 1 to 6 copies in lectins. The domain is also found in the salt-stress induced protein from rice and an animal prostatic spermine-binding protein.


Pssm-ID: 214909 [Multi-domain]  Cd Length: 128  Bit Score: 140.83  E-value: 7.15e-42
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15228214     13 GDVWDDGAHDGVRKVHVGQGLDGVSFINVVYENGsQEVVGGEHGKKSLIGIEtFEVDADDYIVAVQVTYDKifgydSDII 92
Cdd:smart00915   1 GTEWDDGAFDGVRKIYVGQGGEGIKSIQFDYDKG-GKVWGDEHGGKGGTGEE-ILLYPGEYITSVEGTYDK-----SGVI 73

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|...
gi 15228214     93 TSITFSTFKGKTSPPYGLDTENKFVLKEKNGGKLVGFHGR-AGEILYALGAYF 144
Cdd:smart00915  74 TSLTFKTNKGRTSPFGGYEGGTKFVLESKEGKKIVGFHGRsSGDGLDSLGAYF 126
Jacalin cd09612
Jacalin-like plant lectin domain; Jacalin-like lectins are sugar-binding protein domains ...
 13-144 7.10e-38

Jacalin-like plant lectin domain; Jacalin-like lectins are sugar-binding protein domains mostly found in plants. They adopt a beta-prism topology consistent with a circularly permuted three-fold repeat of a structural motif. Proteins containing this domain may bind mono- or oligosaccharides with high specificity. The domain can occur in tandem-repeat arrangements with up to six copies, and in architectures combined with a variety of other functional domains. The family was initially named after an abundant protein found in the jackfruit seed. Jacalin specifically binds to the alpha-O-glycoside of the disaccharide Gal-beta1-3-GalNAc, and has proven useful in the study of O-linked glycoproteins. Jacalin-like lectins in this family may occur in various oligomerization states.


Pssm-ID: 187708 [Multi-domain]  Cd Length: 130  Bit Score: 130.76  E-value: 7.10e-38
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15228214  13 GDVWDDGAH-DGVRKVHVGQGLDGVSFINVVYENGSQEVVGGEHGKKSLiGIETFEVDA-DDYIVAVQVTYDKIFGydSD 90
Cdd:cd09612   1 GSAWDDGVFpDGLRKITVRSGENGIDSIKFEYDKDGQHVVGPWHGGGGG-TPEEIVLDYpDEYITSVSGTYGPVSG--SN 77

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....
gi 15228214  91 IITSITFSTFKgKTSPPYGLDTENKFVLkEKNGGKLVGFHGRAGEILYALGAYF 144
Cdd:cd09612  78 VITSLTFKTNK-RTYGPFGVESGTPFSL-PVEGGKIVGFHGRSGDYLDAIGVYV 129
griffithsin_like cd09614
Jacalin-like lectin domain of griffithsin and related proteins; Griffithsin is a lectin ...
 10-144 5.25e-05

Jacalin-like lectin domain of griffithsin and related proteins; Griffithsin is a lectin isolated from a red alga, which has shown potential as an inhibitor of viral entry, exhibiting antiviral activity against HIV and SARS. The biological functions of griffithsin and griffithsin-like proteins with respect to their source organisms are not known.


Pssm-ID: 187710  Cd Length: 128  Bit Score: 42.00  E-value: 5.25e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15228214  10 GIGGDVWDDGAHDGVRKVHVGQG--LDGVSFINVVYENGSQEVVGGEHGKKSligiETFEVDADDYIVAVQVTYdkifgy 87
Cdd:cd09614   1 GFGGSPGSDFDILTVSAIQLRSGsyVDQIITDYQDLNGTQNFHHGGGGGNLS----PTLNFSSGEYITEVTGRS------ 70

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*..
gi 15228214  88 dSDIITSITFSTFKGKTSPPYGLDTENKFVLKEKNGGKLVGFHGRAGEILYALGAYF 144
Cdd:cd09614  71 -GDRVDQVQFTTNYGGRTLPGGGGGGSAFTWTVPDNQKVIGFAGRSGSYLDQLQVYY 126
Jacalin_like cd09302
Jacalin-like lectin domain; Jacalin-like lectins are sugar-binding protein domains mostly ...
 9-141 1.01e-04

Jacalin-like lectin domain; Jacalin-like lectins are sugar-binding protein domains mostly found in plants. They adopt a beta-prism topology consistent with a circularly permuted three-fold repeat of a structural motif. Proteins containing this domain may bind mono- or oligosaccharides with high specificity. The domain can occur in tandem-repeat arrangements with up to six copies, and in architectures combined with a variety of other functional domains. Taxonomic distribution is not restricted to plants, the domain is also found in various mammalian proteins, for example.


Pssm-ID: 187706  Cd Length: 128  Bit Score: 41.23  E-value: 1.01e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15228214   9 GGIGGDVWDDGAHDGVRKVHVGQGLDGvsfINVVYENGSQEVVGGEHGkkslIGIETFEVDADDYIVAVQVTYDKIFGYD 88
Cdd:cd09302   1 GKPFSDTGGDGARLTEIRVRSGGAVDA---IRVVLRDYTDGRHGGNGG----PNTSSVFLDPGEYITITSVSSGDNGGGT 73

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....
gi 15228214  89 sdIITSITFSTFKGkTSPPYG-LDTENKFVLKEKNGGKLVGFHGRAGEILYALG 141
Cdd:cd09302  74 --RIDAIQFTTNKG-RSGTYGtTSGALGTEFTVPVGGEIVGIYGRAGDDVDAFG 124
Jacalin_like cd09302
Jacalin-like lectin domain; Jacalin-like lectins are sugar-binding protein domains mostly ...
 165-293 1.12e-03

Jacalin-like lectin domain; Jacalin-like lectins are sugar-binding protein domains mostly found in plants. They adopt a beta-prism topology consistent with a circularly permuted three-fold repeat of a structural motif. Proteins containing this domain may bind mono- or oligosaccharides with high specificity. The domain can occur in tandem-repeat arrangements with up to six copies, and in architectures combined with a variety of other functional domains. Taxonomic distribution is not restricted to plants, the domain is also found in various mammalian proteins, for example.


Pssm-ID: 187706  Cd Length: 128  Bit Score: 38.15  E-value: 1.12e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15228214 165 GTAWDDGAFDGVK----KVYIGQAqdgISAVKFVYDKGAEDIVGDEHGNDTllgfEEFQLDyPSEYITAVEGTYDKIFGf 240
Cdd:cd09302   1 GKPFSDTGGDGARlteiRVRSGGA---VDAIRVVLRDYTDGRHGGNGGPNT----SSVFLD-PGEYITITSVSSGDNGG- 71

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*.
gi 15228214 241 eTEVINMLRFKTNKKTSPPFG---IEAGTAFELkEEGCKIVGFHGKVSAVLHQFGV 293
Cdd:cd09302  72 -GTRIDAIQFTTNKGRSGTYGttsGALGTEFTV-PVGGEIVGIYGRAGDDVDAFGF 125
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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