VTA1 family vacuolar protein sorting-associated protein similar to Saccharomyces cerevisiae VTA1 that plays a role in the formation of the multivesicular body (MVB) and is required for the sorting of lipids to form intralumenal vesicles and for fluid-phase transport to the vacuole
1,3-beta-glucan synthase component; This family consists of various 1,3-beta-glucan synthase ...
1107-1835
0e+00
1,3-beta-glucan synthase component; This family consists of various 1,3-beta-glucan synthase components including Gls1, Gls2 and Gls3 from yeast. 1,3-beta-glucan synthase EC:2.4.1.34 also known as callose synthase catalyzes the formation of a beta-1,3-glucan polymer that is a major component of the fungal cell wall. The reaction catalyzed is:- UDP-glucose + {(1,3)-beta-D-glucosyl}(N) <=> UDP + {(1,3)-beta-D-glucosyl}(N+1).
The actual alignment was detected with superfamily member pfam02364:
Pssm-ID: 426739 Cd Length: 818 Bit Score: 787.14 E-value: 0e+00
1,3-beta-glucan synthase subunit FKS1, domain-1; The FKS1_dom1 domain is likely to be the ...
338-451
1.60e-60
1,3-beta-glucan synthase subunit FKS1, domain-1; The FKS1_dom1 domain is likely to be the 'Class I' region just N-terminal to the first set of transmembrane helices that is involved in 1,3-beta-glucan synthesis itself. This family is found on proteins with family Glucan_synthase, pfam02364.
:
Pssm-ID: 464126 Cd Length: 112 Bit Score: 202.84 E-value: 1.60e-60
Vta1 like; Vta1 (VPS20-associated protein 1) is a positive regulator of Vps4. Vps4 is an ...
69-117
1.29e-05
Vta1 like; Vta1 (VPS20-associated protein 1) is a positive regulator of Vps4. Vps4 is an ATPase that is required in the multivesicular body (MVB) sorting pathway to dissociate the endosomal sorting complex required for transport (ESCRT). Vta1 promotes correct assembly of Vps4 and stimulates its ATPase activity through its conserved Vta1/SBP1/LIP5 region.
The actual alignment was detected with superfamily member pfam04652:
Pssm-ID: 461380 Cd Length: 133 Bit Score: 46.79 E-value: 1.29e-05
1,3-beta-glucan synthase component; This family consists of various 1,3-beta-glucan synthase ...
1107-1835
0e+00
1,3-beta-glucan synthase component; This family consists of various 1,3-beta-glucan synthase components including Gls1, Gls2 and Gls3 from yeast. 1,3-beta-glucan synthase EC:2.4.1.34 also known as callose synthase catalyzes the formation of a beta-1,3-glucan polymer that is a major component of the fungal cell wall. The reaction catalyzed is:- UDP-glucose + {(1,3)-beta-D-glucosyl}(N) <=> UDP + {(1,3)-beta-D-glucosyl}(N+1).
Pssm-ID: 426739 Cd Length: 818 Bit Score: 787.14 E-value: 0e+00
1,3-beta-glucan synthase subunit FKS1, domain-1; The FKS1_dom1 domain is likely to be the ...
338-451
1.60e-60
1,3-beta-glucan synthase subunit FKS1, domain-1; The FKS1_dom1 domain is likely to be the 'Class I' region just N-terminal to the first set of transmembrane helices that is involved in 1,3-beta-glucan synthesis itself. This family is found on proteins with family Glucan_synthase, pfam02364.
Pssm-ID: 464126 Cd Length: 112 Bit Score: 202.84 E-value: 1.60e-60
Vta1 like; Vta1 (VPS20-associated protein 1) is a positive regulator of Vps4. Vps4 is an ...
69-117
1.29e-05
Vta1 like; Vta1 (VPS20-associated protein 1) is a positive regulator of Vps4. Vps4 is an ATPase that is required in the multivesicular body (MVB) sorting pathway to dissociate the endosomal sorting complex required for transport (ESCRT). Vta1 promotes correct assembly of Vps4 and stimulates its ATPase activity through its conserved Vta1/SBP1/LIP5 region.
Pssm-ID: 461380 Cd Length: 133 Bit Score: 46.79 E-value: 1.29e-05
1,3-beta-glucan synthase component; This family consists of various 1,3-beta-glucan synthase ...
1107-1835
0e+00
1,3-beta-glucan synthase component; This family consists of various 1,3-beta-glucan synthase components including Gls1, Gls2 and Gls3 from yeast. 1,3-beta-glucan synthase EC:2.4.1.34 also known as callose synthase catalyzes the formation of a beta-1,3-glucan polymer that is a major component of the fungal cell wall. The reaction catalyzed is:- UDP-glucose + {(1,3)-beta-D-glucosyl}(N) <=> UDP + {(1,3)-beta-D-glucosyl}(N+1).
Pssm-ID: 426739 Cd Length: 818 Bit Score: 787.14 E-value: 0e+00
1,3-beta-glucan synthase subunit FKS1, domain-1; The FKS1_dom1 domain is likely to be the ...
338-451
1.60e-60
1,3-beta-glucan synthase subunit FKS1, domain-1; The FKS1_dom1 domain is likely to be the 'Class I' region just N-terminal to the first set of transmembrane helices that is involved in 1,3-beta-glucan synthesis itself. This family is found on proteins with family Glucan_synthase, pfam02364.
Pssm-ID: 464126 Cd Length: 112 Bit Score: 202.84 E-value: 1.60e-60
Vta1 like; Vta1 (VPS20-associated protein 1) is a positive regulator of Vps4. Vps4 is an ...
69-117
1.29e-05
Vta1 like; Vta1 (VPS20-associated protein 1) is a positive regulator of Vps4. Vps4 is an ATPase that is required in the multivesicular body (MVB) sorting pathway to dissociate the endosomal sorting complex required for transport (ESCRT). Vta1 promotes correct assembly of Vps4 and stimulates its ATPase activity through its conserved Vta1/SBP1/LIP5 region.
Pssm-ID: 461380 Cd Length: 133 Bit Score: 46.79 E-value: 1.29e-05
Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
References:
Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
of the residues that compose this conserved feature have been mapped to the query sequence.
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