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Conserved domains on  [gi|22330951|ref|NP_187625|]
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RECA homolog 3 [Arabidopsis thaliana]

Protein Classification

DNA recombination/repair protein RecA( domain architecture ID 10097303)

DNA recombination/repair protein RecA catalyzes an ATP-dependent DNA strand-exchange reaction, which is a critical step in the repair of DNA double-strand breaks by homologous recombination

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
RecA cd00983
recombinase A; RecA is a bacterial enzyme which has roles in homologous recombination, DNA ...
 93-329 7.09e-117

recombinase A; RecA is a bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response. RecA couples ATP hydrolysis to DNA strand exchange.


:

Pssm-ID: 410863 [Multi-domain]  Cd Length: 235  Bit Score: 339.15  E-value: 7.09e-117
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22330951  93 RVSVISTGSLNLDLALGVGGLPKGRMVEVYGKEASGKTTLALHIIKEAQKLGGYCAYLDAENAMDPSLAESIGVNTEELL 172
Cdd:cd00983   1 DVEVIPTGSLSLDIALGIGGLPRGRIIEIYGPESSGKTTLALHAIAEAQKLGGTAAFIDAEHALDPEYAKKLGVDIDNLL 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22330951 173 ISRPSSAEKMLNIVDVLTKSGSVDVIVVDSVAALAPQCELDAPVGERYRDTQSRIMTQALRKIHYSVGYSQTLIVFLNQV 252
Cdd:cd00983  81 VSQPDTGEQALEIADTLIRSGAVDLIVVDSVAALVPKAEIEGEMGDSHVGLQARLMSQALRKLTGSLSKSKTTVIFINQL 160

                       170       180       190       200       210       220       230
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 22330951 253 RSHVKSnmhFPHAEEVTCGGNALPFHAAIRLKMIRTGLIKTANKISGLNVCVQVVKNKLAPGKKKSELGIHFGHGFY 329
Cdd:cd00983 161 REKIGV---MFGNPETTTGGNALKFYASVRLDIRRIELIKEGEDVIGNRTKVKVVKNKVAPPFKQAEFDILYGEGIS 234
 
Name Accession Description Interval E-value
RecA cd00983
recombinase A; RecA is a bacterial enzyme which has roles in homologous recombination, DNA ...
 93-329 7.09e-117

recombinase A; RecA is a bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response. RecA couples ATP hydrolysis to DNA strand exchange.


Pssm-ID: 410863 [Multi-domain]  Cd Length: 235  Bit Score: 339.15  E-value: 7.09e-117
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22330951  93 RVSVISTGSLNLDLALGVGGLPKGRMVEVYGKEASGKTTLALHIIKEAQKLGGYCAYLDAENAMDPSLAESIGVNTEELL 172
Cdd:cd00983   1 DVEVIPTGSLSLDIALGIGGLPRGRIIEIYGPESSGKTTLALHAIAEAQKLGGTAAFIDAEHALDPEYAKKLGVDIDNLL 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22330951 173 ISRPSSAEKMLNIVDVLTKSGSVDVIVVDSVAALAPQCELDAPVGERYRDTQSRIMTQALRKIHYSVGYSQTLIVFLNQV 252
Cdd:cd00983  81 VSQPDTGEQALEIADTLIRSGAVDLIVVDSVAALVPKAEIEGEMGDSHVGLQARLMSQALRKLTGSLSKSKTTVIFINQL 160

                       170       180       190       200       210       220       230
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 22330951 253 RSHVKSnmhFPHAEEVTCGGNALPFHAAIRLKMIRTGLIKTANKISGLNVCVQVVKNKLAPGKKKSELGIHFGHGFY 329
Cdd:cd00983 161 REKIGV---MFGNPETTTGGNALKFYASVRLDIRRIELIKEGEDVIGNRTKVKVVKNKVAPPFKQAEFDILYGEGIS 234
recA PRK09354
recombinase A; Provisional
 60-386 2.96e-105

recombinase A; Provisional


Pssm-ID: 236476 [Multi-domain]  Cd Length: 349  Bit Score: 314.04  E-value: 2.96e-105
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22330951   60 AEKDTALHLALSQLSGDFDKDSKLSLQRFyRKRRVSVISTGSLNLDLALGVGGLPKGRMVEVYGKEASGKTTLALHIIKE 139
Cdd:PRK09354   5 EEKQKALEAALKQIEKQFGKGSIMRLGDD-AAMDVEVISTGSLALDIALGIGGLPRGRIVEIYGPESSGKTTLALHAIAE 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22330951  140 AQKLGGYCAYLDAENAMDPSLAESIGVNTEELLISRPSSAEKMLNIVDVLTKSGSVDVIVVDSVAALAPQCELDAPVGER 219
Cdd:PRK09354  84 AQKAGGTAAFIDAEHALDPVYAKKLGVDIDNLLVSQPDTGEQALEIADTLVRSGAVDLIVVDSVAALVPKAEIEGEMGDS 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22330951  220 YRDTQSRIMTQALRKIHYSVGYSQTLIVFLNQVRShvKSNMHF--PhaeEVTCGGNALPFHAAIRLKMIRTGLIKTANKI 297
Cdd:PRK09354 164 HVGLQARLMSQALRKLTGNISKSNTTVIFINQIRE--KIGVMFgnP---ETTTGGNALKFYASVRLDIRRIGTIKDGDEV 238

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22330951  298 SGLNVCVQVVKNKLAPGKKKSELGIHFGHGFYVEREVLELACEHGVILREGTSYFIEGEVI-EGKDAAEKYLVENKEALD 376
Cdd:PRK09354 239 IGNRTKVKVVKNKVAPPFKQAEFDIMYGEGISREGELIDLGVELGIIEKSGAWYSYNGEKIgQGRENAKQYLKENPELAD 318

                        330
                 ....*....|
gi 22330951  377 TVVAILRNQL 386
Cdd:PRK09354 319 EIEKKIREKL 328
RecA COG0468
RecA/RadA recombinase [Replication, recombination and repair];
60-386 4.86e-103

RecA/RadA recombinase [Replication, recombination and repair];


Pssm-ID: 440236 [Multi-domain]  Cd Length: 351  Bit Score: 308.25  E-value: 4.86e-103
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22330951  60 AEKDTALHLALSQLSGDFDKDSKLSLQRfYRKRRVSVISTGSLNLDLALGVGGLPKGRMVEVYGKEASGKTTLALHIIKE 139
Cdd:COG0468   8 SEKEKALEAALSQIEKQFGKGSIMRLGD-KARQDVEVISTGSLALDIALGVGGLPRGRIVEIYGPESSGKTTLALHAIAE 86

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22330951 140 AQKLGGYCAYLDAENAMDPSLAESIGVNTEELLISRPSSAEKMLNIVDVLTKSGSVDVIVVDSVAALAPQCELDAPVGER 219
Cdd:COG0468  87 AQKAGGIAAFIDAEHALDPEYAKKLGVDIDNLLVSQPDTGEQALEIAETLVRSGAVDLIVVDSVAALVPKAEIEGEMGDS 166

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22330951 220 YRDTQSRIMTQALRKIHYSVGYSQTLIVFLNQVRShvKSNMHF--PhaeEVTCGGNALPFHAAIRLKMIRTGLIKTANKI 297
Cdd:COG0468 167 HVGLQARLMSQALRKLTGAISKSNTTVIFINQLRE--KIGVMFgnP---ETTTGGNALKFYASVRLDIRRIGTIKDGDEV 241

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22330951 298 SGLNVCVQVVKNKLAPGKKKSELGIHFGHGFYVEREVLELACEHGVILREGTSYFIEGEVI-EGKDAAEKYLVENKEALD 376
Cdd:COG0468 242 IGNRTRVKVVKNKVAPPFKEAEFDIMYGEGISKEGELLDLAVELGIIEKSGAWYSYGGERLgQGRENAKQFLKENPELAE 321

                       330
                ....*....|
gi 22330951 377 TVVAILRNQL 386
Cdd:COG0468 322 EIEAKIREKL 331
tigrfam_recA TIGR02012
protein RecA; This model describes orthologs of the recA protein. RecA promotes hybridization ...
 61-378 1.58e-101

protein RecA; This model describes orthologs of the recA protein. RecA promotes hybridization of homolgous regions of DNA. A segment of ssDNA can be hybridized to another ssDNA region, or to a dsDNA region. ATP is hydrolyzed in the process. Part of the SOS respones, it is regulated by LexA via autocatalytic cleavage. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 162659 [Multi-domain]  Cd Length: 321  Bit Score: 303.52  E-value: 1.58e-101
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22330951    61 EKDTALHLALSQLSGDFDKDSKLSLQRfYRKRRVSVISTGSLNLDLALGVGGLPKGRMVEVYGKEASGKTTLALHIIKEA 140
Cdd:TIGR02012   1 DKQKALEAALAQIEKQFGKGSIMRLGE-KTVMDVETISTGSLALDLALGVGGLPKGRIIEIYGPESSGKTTLALHAIAEA 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22330951   141 QKLGGYCAYLDAENAMDPSLAESIGVNTEELLISRPSSAEKMLNIVDVLTKSGSVDVIVVDSVAALAPQCELDAPVGERY 220
Cdd:TIGR02012  80 QKAGGTAAFIDAEHALDPVYARKLGVDIDNLLVSQPDTGEQALEIAETLVRSGAVDIIVVDSVAALVPKAEIEGEMGDSH 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22330951   221 RDTQSRIMTQALRKIHYSVGYSQTLIVFLNQVRSHVKSNMHFPhaeEVTCGGNALPFHAAIRLKMIRTGLIKTANKISGL 300
Cdd:TIGR02012 160 VGLQARLMSQALRKLTGALSKSNTTAIFINQIREKIGVMFGNP---ETTTGGNALKFYASVRLDIRRIGTVKQGEEVVGN 236

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 22330951   301 NVCVQVVKNKLAPGKKKSELGIHFGHGFYVEREVLELACEHGVILREGTSYFIEGEVI-EGKDAAEKYLVENKEALDTV 378
Cdd:TIGR02012 237 RTKVKVVKNKVAPPFREAEFDILYGEGISKLGEIIDLAVELDIIKKSGSWYSYGDEKLgQGRENAKAFLKENPELAQEI 315
RecA pfam00154
recA bacterial DNA recombination protein; RecA is a DNA-dependent ATPase and functions in DNA ...
 65-328 4.72e-89

recA bacterial DNA recombination protein; RecA is a DNA-dependent ATPase and functions in DNA repair systems. RecA protein catalyzes an ATP-dependent DNA strand-exchange reaction that is the central step in the repair of dsDNA breaks by homologous recombination.


Pssm-ID: 425488 [Multi-domain]  Cd Length: 262  Bit Score: 269.65  E-value: 4.72e-89
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22330951    65 ALHLALSQLSGDFDKDSKLSLQRfYRKRRVSVISTGSLNLDLALGVGGLPKGRMVEVYGKEASGKTTLALHIIKEAQKLG 144
Cdd:pfam00154   2 ALEAALKQIEKQFGKGSIMKLGD-EKKLDVETISTGSLALDIALGIGGYPKGRIIEIYGPESSGKTTLALHAIAEAQKAG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22330951   145 GYCAYLDAENAMDPSLAESIGVNTEELLISRPSSAEKMLNIVDVLTKSGSVDVIVVDSVAALAPQCELDAPVGERYRDTQ 224
Cdd:pfam00154  81 GTAAFIDAEHALDPVYAKKLGVDIDNLLVSQPDTGEQALEIADMLVRSGAIDLIVVDSVAALVPKAEIEGEMGDSHVGLQ 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22330951   225 SRIMTQALRKIHYSVGYSQTLIVFLNQVRSHVKSNMHFPhaeEVTCGGNALPFHAAIRLKMIRTGLIKTANKISGLNVCV 304
Cdd:pfam00154 161 ARLMSQALRKLTGSISKSNTTVIFINQIREKIGVMFGNP---ETTTGGRALKFYASVRLDIRRIGQIKQGEEVIGNKTKV 237

                         250       260
                  ....*....|....*....|....
gi 22330951   305 QVVKNKLAPGKKKSELGIHFGHGF 328
Cdd:pfam00154 238 KVVKNKVAPPFKEAEFDIMYGEGI 261
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
 115-170 3.33e-03

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 37.74  E-value: 3.33e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 22330951    115 KGRMVEVYGKEASGKTTLALHIIKEAQKLGGYCAYLDAENAMDPSLAESIGVNTEE 170
Cdd:smart00382   1 PGEVILIVGPPGSGKTTLARALARELGPPGGGVIYIDGEDILEEVLDQLLLIIVGG 56
 
Name Accession Description Interval E-value
RecA cd00983
recombinase A; RecA is a bacterial enzyme which has roles in homologous recombination, DNA ...
 93-329 7.09e-117

recombinase A; RecA is a bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response. RecA couples ATP hydrolysis to DNA strand exchange.


Pssm-ID: 410863 [Multi-domain]  Cd Length: 235  Bit Score: 339.15  E-value: 7.09e-117
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22330951  93 RVSVISTGSLNLDLALGVGGLPKGRMVEVYGKEASGKTTLALHIIKEAQKLGGYCAYLDAENAMDPSLAESIGVNTEELL 172
Cdd:cd00983   1 DVEVIPTGSLSLDIALGIGGLPRGRIIEIYGPESSGKTTLALHAIAEAQKLGGTAAFIDAEHALDPEYAKKLGVDIDNLL 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22330951 173 ISRPSSAEKMLNIVDVLTKSGSVDVIVVDSVAALAPQCELDAPVGERYRDTQSRIMTQALRKIHYSVGYSQTLIVFLNQV 252
Cdd:cd00983  81 VSQPDTGEQALEIADTLIRSGAVDLIVVDSVAALVPKAEIEGEMGDSHVGLQARLMSQALRKLTGSLSKSKTTVIFINQL 160

                       170       180       190       200       210       220       230
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 22330951 253 RSHVKSnmhFPHAEEVTCGGNALPFHAAIRLKMIRTGLIKTANKISGLNVCVQVVKNKLAPGKKKSELGIHFGHGFY 329
Cdd:cd00983 161 REKIGV---MFGNPETTTGGNALKFYASVRLDIRRIELIKEGEDVIGNRTKVKVVKNKVAPPFKQAEFDILYGEGIS 234
recA PRK09354
recombinase A; Provisional
 60-386 2.96e-105

recombinase A; Provisional


Pssm-ID: 236476 [Multi-domain]  Cd Length: 349  Bit Score: 314.04  E-value: 2.96e-105
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22330951   60 AEKDTALHLALSQLSGDFDKDSKLSLQRFyRKRRVSVISTGSLNLDLALGVGGLPKGRMVEVYGKEASGKTTLALHIIKE 139
Cdd:PRK09354   5 EEKQKALEAALKQIEKQFGKGSIMRLGDD-AAMDVEVISTGSLALDIALGIGGLPRGRIVEIYGPESSGKTTLALHAIAE 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22330951  140 AQKLGGYCAYLDAENAMDPSLAESIGVNTEELLISRPSSAEKMLNIVDVLTKSGSVDVIVVDSVAALAPQCELDAPVGER 219
Cdd:PRK09354  84 AQKAGGTAAFIDAEHALDPVYAKKLGVDIDNLLVSQPDTGEQALEIADTLVRSGAVDLIVVDSVAALVPKAEIEGEMGDS 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22330951  220 YRDTQSRIMTQALRKIHYSVGYSQTLIVFLNQVRShvKSNMHF--PhaeEVTCGGNALPFHAAIRLKMIRTGLIKTANKI 297
Cdd:PRK09354 164 HVGLQARLMSQALRKLTGNISKSNTTVIFINQIRE--KIGVMFgnP---ETTTGGNALKFYASVRLDIRRIGTIKDGDEV 238

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22330951  298 SGLNVCVQVVKNKLAPGKKKSELGIHFGHGFYVEREVLELACEHGVILREGTSYFIEGEVI-EGKDAAEKYLVENKEALD 376
Cdd:PRK09354 239 IGNRTKVKVVKNKVAPPFKQAEFDIMYGEGISREGELIDLGVELGIIEKSGAWYSYNGEKIgQGRENAKQYLKENPELAD 318

                        330
                 ....*....|
gi 22330951  377 TVVAILRNQL 386
Cdd:PRK09354 319 EIEKKIREKL 328
RecA COG0468
RecA/RadA recombinase [Replication, recombination and repair];
60-386 4.86e-103

RecA/RadA recombinase [Replication, recombination and repair];


Pssm-ID: 440236 [Multi-domain]  Cd Length: 351  Bit Score: 308.25  E-value: 4.86e-103
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22330951  60 AEKDTALHLALSQLSGDFDKDSKLSLQRfYRKRRVSVISTGSLNLDLALGVGGLPKGRMVEVYGKEASGKTTLALHIIKE 139
Cdd:COG0468   8 SEKEKALEAALSQIEKQFGKGSIMRLGD-KARQDVEVISTGSLALDIALGVGGLPRGRIVEIYGPESSGKTTLALHAIAE 86

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22330951 140 AQKLGGYCAYLDAENAMDPSLAESIGVNTEELLISRPSSAEKMLNIVDVLTKSGSVDVIVVDSVAALAPQCELDAPVGER 219
Cdd:COG0468  87 AQKAGGIAAFIDAEHALDPEYAKKLGVDIDNLLVSQPDTGEQALEIAETLVRSGAVDLIVVDSVAALVPKAEIEGEMGDS 166

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22330951 220 YRDTQSRIMTQALRKIHYSVGYSQTLIVFLNQVRShvKSNMHF--PhaeEVTCGGNALPFHAAIRLKMIRTGLIKTANKI 297
Cdd:COG0468 167 HVGLQARLMSQALRKLTGAISKSNTTVIFINQLRE--KIGVMFgnP---ETTTGGNALKFYASVRLDIRRIGTIKDGDEV 241

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22330951 298 SGLNVCVQVVKNKLAPGKKKSELGIHFGHGFYVEREVLELACEHGVILREGTSYFIEGEVI-EGKDAAEKYLVENKEALD 376
Cdd:COG0468 242 IGNRTRVKVVKNKVAPPFKEAEFDIMYGEGISKEGELLDLAVELGIIEKSGAWYSYGGERLgQGRENAKQFLKENPELAE 321

                       330
                ....*....|
gi 22330951 377 TVVAILRNQL 386
Cdd:COG0468 322 EIEAKIREKL 331
tigrfam_recA TIGR02012
protein RecA; This model describes orthologs of the recA protein. RecA promotes hybridization ...
 61-378 1.58e-101

protein RecA; This model describes orthologs of the recA protein. RecA promotes hybridization of homolgous regions of DNA. A segment of ssDNA can be hybridized to another ssDNA region, or to a dsDNA region. ATP is hydrolyzed in the process. Part of the SOS respones, it is regulated by LexA via autocatalytic cleavage. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 162659 [Multi-domain]  Cd Length: 321  Bit Score: 303.52  E-value: 1.58e-101
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22330951    61 EKDTALHLALSQLSGDFDKDSKLSLQRfYRKRRVSVISTGSLNLDLALGVGGLPKGRMVEVYGKEASGKTTLALHIIKEA 140
Cdd:TIGR02012   1 DKQKALEAALAQIEKQFGKGSIMRLGE-KTVMDVETISTGSLALDLALGVGGLPKGRIIEIYGPESSGKTTLALHAIAEA 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22330951   141 QKLGGYCAYLDAENAMDPSLAESIGVNTEELLISRPSSAEKMLNIVDVLTKSGSVDVIVVDSVAALAPQCELDAPVGERY 220
Cdd:TIGR02012  80 QKAGGTAAFIDAEHALDPVYARKLGVDIDNLLVSQPDTGEQALEIAETLVRSGAVDIIVVDSVAALVPKAEIEGEMGDSH 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22330951   221 RDTQSRIMTQALRKIHYSVGYSQTLIVFLNQVRSHVKSNMHFPhaeEVTCGGNALPFHAAIRLKMIRTGLIKTANKISGL 300
Cdd:TIGR02012 160 VGLQARLMSQALRKLTGALSKSNTTAIFINQIREKIGVMFGNP---ETTTGGNALKFYASVRLDIRRIGTVKQGEEVVGN 236

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 22330951   301 NVCVQVVKNKLAPGKKKSELGIHFGHGFYVEREVLELACEHGVILREGTSYFIEGEVI-EGKDAAEKYLVENKEALDTV 378
Cdd:TIGR02012 237 RTKVKVVKNKVAPPFREAEFDILYGEGISKLGEIIDLAVELDIIKKSGSWYSYGDEKLgQGRENAKAFLKENPELAQEI 315
RecA pfam00154
recA bacterial DNA recombination protein; RecA is a DNA-dependent ATPase and functions in DNA ...
 65-328 4.72e-89

recA bacterial DNA recombination protein; RecA is a DNA-dependent ATPase and functions in DNA repair systems. RecA protein catalyzes an ATP-dependent DNA strand-exchange reaction that is the central step in the repair of dsDNA breaks by homologous recombination.


Pssm-ID: 425488 [Multi-domain]  Cd Length: 262  Bit Score: 269.65  E-value: 4.72e-89
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22330951    65 ALHLALSQLSGDFDKDSKLSLQRfYRKRRVSVISTGSLNLDLALGVGGLPKGRMVEVYGKEASGKTTLALHIIKEAQKLG 144
Cdd:pfam00154   2 ALEAALKQIEKQFGKGSIMKLGD-EKKLDVETISTGSLALDIALGIGGYPKGRIIEIYGPESSGKTTLALHAIAEAQKAG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22330951   145 GYCAYLDAENAMDPSLAESIGVNTEELLISRPSSAEKMLNIVDVLTKSGSVDVIVVDSVAALAPQCELDAPVGERYRDTQ 224
Cdd:pfam00154  81 GTAAFIDAEHALDPVYAKKLGVDIDNLLVSQPDTGEQALEIADMLVRSGAIDLIVVDSVAALVPKAEIEGEMGDSHVGLQ 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22330951   225 SRIMTQALRKIHYSVGYSQTLIVFLNQVRSHVKSNMHFPhaeEVTCGGNALPFHAAIRLKMIRTGLIKTANKISGLNVCV 304
Cdd:pfam00154 161 ARLMSQALRKLTGSISKSNTTVIFINQIREKIGVMFGNP---ETTTGGRALKFYASVRLDIRRIGQIKQGEEVIGNKTKV 237

                         250       260
                  ....*....|....*....|....
gi 22330951   305 QVVKNKLAPGKKKSELGIHFGHGF 328
Cdd:pfam00154 238 KVVKNKVAPPFKEAEFDIMYGEGI 261
recA PRK09519
intein-containing recombinase RecA;
58-316 1.05e-58

intein-containing recombinase RecA;


Pssm-ID: 77219 [Multi-domain]  Cd Length: 790  Bit Score: 203.79  E-value: 1.05e-58
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22330951   58 KVAEKDTALHLALSQLSGDFDKDSKLSLQRFYRKRrVSVISTGSLNLDLALGVGGLPKGRMVEVYGKEASGKTTLALHII 137
Cdd:PRK09519   3 QTPDREKALELAVAQIEKSYGKGSVMRLGDEARQP-ISVIPTGSIALDVALGIGGLPRGRVIEIYGPESSGKTTVALHAV 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22330951  138 KEAQKLGGYCAYLDAENAMDPSLAESIGVNTEELLISRPSSAEKMLNIVDVLTKSGSVDVIVVDSVAALAPQCELDAPVG 217
Cdd:PRK09519  82 ANAQAAGGVAAFIDAEHALDPDYAKKLGVDTDSLLVSQPDTGEQALEIADMLIRSGALDIVVIDSVAALVPRAELEGEMG 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22330951  218 ERYRDTQSRIMTQALRKIHYSVGYSQTLIVFLNQVRSHVKSNMHFPhaeEVTCGGNALPFHAAIRLKMIRTGLIKTANKI 297
Cdd:PRK09519 162 DSHVGLQARLMSQALRKMTGALNNSGTTAIFINQLRDKIGVMFGSP---ETTTGGKALKFYASVRMDVRRVETLKDGTNA 238

                        250       260
                 ....*....|....*....|
gi 22330951  298 SGLNVCVQVVKNK-LAPGKK 316
Cdd:PRK09519 239 VGNRTRVKVVKNKcLAEGTR 258
RecA-like cd01393
RecA family; RecA is a bacterial enzyme which has roles in homologous recombination, DNA ...
 116-283 1.11e-14

RecA family; RecA is a bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response. RecA couples ATP hydrolysis to DNA strand exchange. While prokaryotes have a single RecA protein, eukaryotes have multiple RecA homologs such as Rad51, DMC1 and Rad55/57. Archaea have the RecA-like homologs RadA and RadB.


Pssm-ID: 410881 [Multi-domain]  Cd Length: 185  Bit Score: 71.61  E-value: 1.11e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22330951 116 GRMVEVYGKEASGKTTLALHIIKEAQKLGGYCAYLDAENAMDPSLAESI-----------GVNTEELLISRPSSAEKMLN 184
Cdd:cd01393   1 GKITEIYGPPGSGKTQLALQLAANALLLGGGVVWIDTEGAFPPSRLVQIleaspsselelAEALSRLLYFRPPDTLAHLL 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22330951 185 IVDVLTKSGSVDVIVVD----SVAALAPQCELDAPVGERYRDTQSRIMTQALRKIHYSVGYSQTLIVFLNQVRSHVKS-- 258
Cdd:cd01393  81 ALDSLPESLFPPPNTSLvvvdSVSALFRKAFPRGGDGDSSSSLRARLLSQLARALQKLAAQFNLAVVVTNQVTTKIRGgs 160

                       170       180
                ....*....|....*....|....*.
gi 22330951 259 -NMHFPHAeevtcGGNALPFHAAIRL 283
Cdd:cd01393 161 gASLVPPA-----LGNTWEHSVSTRL 181
RAD55 COG0467
RecA-superfamily ATPase, KaiC/GvpD/RAD55 family [Signal transduction mechanisms];
97-192 1.28e-08

RecA-superfamily ATPase, KaiC/GvpD/RAD55 family [Signal transduction mechanisms];


Pssm-ID: 440235 [Multi-domain]  Cd Length: 221  Bit Score: 54.92  E-value: 1.28e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22330951  97 ISTGSLNLDLALGvGGLPKGRMVEVYGKEASGKTTLALHIIKEAQKLGGYCAYLDAENAMDPSL--AESIGVNTEELLis 174
Cdd:COG0467   2 VPTGIPGLDELLG-GGLPRGSSTLLSGPPGTGKTTLALQFLAEGLRRGEKGLYVSFEESPEQLLrrAESLGLDLEEYI-- 78

                        90
                ....*....|....*...
gi 22330951 175 rpssAEKMLNIVDVLTKS 192
Cdd:COG0467  79 ----ESGLLRIIDLSPEE 92
archRadB cd01394
archaeal RadB; The archaeal protein RadB shares similarity RadA, the archaeal functional ...
 97-153 1.03e-07

archaeal RadB; The archaeal protein RadB shares similarity RadA, the archaeal functional homologue to the bacterial RecA. The precise function of RadB is unclear.


Pssm-ID: 410882 [Multi-domain]  Cd Length: 216  Bit Score: 51.93  E-value: 1.03e-07
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*..
gi 22330951  97 ISTGSLNLDLALGvGGLPKGRMVEVYGKEASGKTTLALHIIKEAQKLGGYCAYLDAE 153
Cdd:cd01394   1 LSTGSKSLDSLLG-GGVERGTITQIYGPPGSGKTNICLQLAVEAAKQGKKVVYIDTE 56
radA PRK04301
DNA repair and recombination protein RadA; Validated
 91-172 2.75e-07

DNA repair and recombination protein RadA; Validated


Pssm-ID: 235273 [Multi-domain]  Cd Length: 317  Bit Score: 51.80  E-value: 2.75e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22330951   91 KRRVSV--ISTGSLNLDLALGvGGLPKGRMVEVYGKEASGKTTLA------LHIIKEAQKLGGYCAYLDAENAMDP---- 158
Cdd:PRK04301  76 ERRKNVgkITTGSKELDELLG-GGIETQSITEFYGEFGSGKTQIChqlavnVQLPEEKGGLEGKAVYIDTEGTFRPerie 154

                         90
                 ....*....|....
gi 22330951  159 SLAESIGVNTEELL 172
Cdd:PRK04301 155 QMAEALGLDPDEVL 168
archRadA cd19515
archaeal recombinase Rad51/RadA; This group includes the archaeal protein RadA which is a ...
 97-172 3.91e-07

archaeal recombinase Rad51/RadA; This group includes the archaeal protein RadA which is a homolog of Rad51. RAD51 recombinase plays an essential role in DNA repair by homologous recombination (HR)


Pssm-ID: 410923 [Multi-domain]  Cd Length: 233  Bit Score: 50.44  E-value: 3.91e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22330951  97 ISTGSLNLDLALGvGGLPKGRMVEVYGKEASGKTTLA------LHIIKEAQKLGGYCAYLDAENAMDP----SLAESIGV 166
Cdd:cd19515   1 ISTGSKELDKLLG-GGIETQAITEVFGEFGSGKTQLChqlavnVQLPPEEGGLNGKAVYIDTENTFRPerimQMAKALGL 79


                ....*.
gi 22330951 167 NTEELL 172
Cdd:cd19515  80 DPDEVL 85
radB PRK09361
DNA repair and recombination protein RadB; Provisional
 95-180 4.75e-07

DNA repair and recombination protein RadB; Provisional


Pssm-ID: 236482 [Multi-domain]  Cd Length: 225  Bit Score: 50.25  E-value: 4.75e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22330951   95 SVISTGSLNLDLALGvGGLPKGRMVEVYGKEASGKTTLALHIIKEAQKLGGYCAYLDAE-------NAMDPSLAESIgvn 167
Cdd:PRK09361   3 ERLPTGCKMLDELLG-GGFERGTITQIYGPPGSGKTNICLQLAVEAAKNGKKVIYIDTEglsperfKQIAGEDFEEL--- 78

                         90
                 ....*....|...
gi 22330951  168 TEELLISRPSSAE 180
Cdd:PRK09361  79 LSNIIIFEPSSFE 91
Rad51_DMC1_archRadA cd01123
recombinase Rad51, DMC1, and archaeal RadA; This group of recombinases includes the eukaryotic ...
 97-187 7.50e-07

recombinase Rad51, DMC1, and archaeal RadA; This group of recombinases includes the eukaryotic proteins RAD51, RAD55/57 and the meiosis-specific protein DMC1, and the archaeal protein RadA. They are closely related to the bacterial RecA group. Rad51 proteins catalyze a similar recombination reaction as RecA, using ATP-dependent DNA binding activity and a DNA-dependent ATPase. However, this reaction is less efficient and requires accessory proteins such as RAD55/57 .


Pssm-ID: 410868 [Multi-domain]  Cd Length: 234  Bit Score: 49.84  E-value: 7.50e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22330951  97 ISTGSLNLDLALGvGGLPKGRMVEVYGKEASGKTTLALHIIKEAQ------KLGGYCAYLDAENAMDP----SLAESIGV 166
Cdd:cd01123   1 ITTGSKELDKLLG-GGIETGSITEMFGEFRTGKTQLCHTLAVTCQlpidrgGGEGKAIYIDTEGTFRPerlrAIAQRFGL 79

                        90       100
                ....*....|....*....|....*
gi 22330951 167 NTEELL----ISRPSSAEKMLNIVD 187
Cdd:cd01123  80 DPDDVLdnvaYARAFNSDHQTQLLD 104
Rad51 pfam08423
Rad51; Rad51 is a DNA repair and recombination protein and is a homolog of the bacterial ...
 90-173 1.11e-06

Rad51; Rad51 is a DNA repair and recombination protein and is a homolog of the bacterial ATPase RecA protein.


Pssm-ID: 462471 [Multi-domain]  Cd Length: 255  Bit Score: 49.61  E-value: 1.11e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22330951    90 RKRRVSVISTGSLNLDLALGvGGLPKGRMVEVYGKEASGKT----TLAL--HIIKEAQKLGGYCAYLDAENAMDP----S 159
Cdd:pfam08423  12 RRSELIQITTGSKELDKLLG-GGIETGSITEIFGEFRTGKTqlchTLCVtcQLPLEMGGGEGKALYIDTEGTFRPerlvA 90

                          90
                  ....*....|....
gi 22330951   160 LAESIGVNTEELLI 173
Cdd:pfam08423  91 IAERYGLDPEDVLD 104
recomb_RAD51 TIGR02239
DNA repair protein RAD51; This eukaryotic sequence family consists of RAD51, a protein ...
 89-172 2.07e-06

DNA repair protein RAD51; This eukaryotic sequence family consists of RAD51, a protein involved in DNA homologous recombination and repair. It is similar in sequence the exclusively meiotic recombinase DMC1 (TIGR02238), to archaeal families RadA (TIGR02236) and RadB (TIGR02237), and to bacterial RecA (TIGR02012).


Pssm-ID: 274048 [Multi-domain]  Cd Length: 316  Bit Score: 48.95  E-value: 2.07e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22330951    89 YRKRRVSVI--STGSLNLDLALGvGGLPKGRMVEVYGKEASGKT----TLALHIIKEAQKLG--GYCAYLDAENAMDP-- 158
Cdd:TIGR02239  68 FHQRRQEVIqlTTGSKELDKLLG-GGIETGSITEIFGEFRTGKTqlchTLAVTCQLPIDQGGgeGKALYIDTEGTFRPer 146

                          90
                  ....*....|....*.
gi 22330951   159 --SLAESIGVNTEELL 172
Cdd:TIGR02239 147 llAIAERYGLNPEDVL 162
KaiC-like_N cd19488
N-terminal domain of KaiC family protein; uncharacterized subfamily; KaiC is a circadian clock ...
 97-150 3.08e-06

N-terminal domain of KaiC family protein; uncharacterized subfamily; KaiC is a circadian clock protein, most studied in cyanobacteria. KaiC, an autokinase, autophosphatase, and ATPase, is part of the core oscillator, composed of three proteins: KaiA, KaiB, and KaiC. The circadian oscillation is regulated via KaiC phosphorylation.


Pssm-ID: 410896 [Multi-domain]  Cd Length: 225  Bit Score: 47.73  E-value: 3.08e-06
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....
gi 22330951  97 ISTGSLNLDLALGvGGLPKGRMVEVYGKEASGKTTLALHIIKEAQKLGGYCAYL 150
Cdd:cd19488   1 ISTGIPGLDDILR-GGLPPRRLYLVEGAPGTGKTTLALQFLLEGAANGETGLYI 53
COG4544 COG4544
Uncharacterized conserved protein [Function unknown];
92-183 1.18e-05

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 443609 [Multi-domain]  Cd Length: 230  Bit Score: 46.08  E-value: 1.18e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22330951  92 RRVSVISTGSLNLDLALGVGGLPKGRMVEVYGKEA-SGKTTLALHIIKEAQKLGGYCAYLDAE---NAmdPSLAEsIGVN 167
Cdd:COG4544  24 AARAVLPTGFAALDAALPGGGLPRGALHEILGPAPgIGELGLLLPLLARLAQAGGPVLWIAPPydlYA--PGLAA-AGLD 100

                        90
                ....*....|....*.
gi 22330951 168 TEELLISRPSSAEKML 183
Cdd:COG4544 101 PERLLLVRARRPADAL 116
recomb_DMC1 TIGR02238
meiotic recombinase Dmc1; This model describes DMC1, a subfamily of a larger family of DNA ...
 90-189 2.20e-05

meiotic recombinase Dmc1; This model describes DMC1, a subfamily of a larger family of DNA repair and recombination proteins. It is eukaryotic only and most closely related to eukaryotic RAD51. It also resembles archaeal RadA (TIGR02236) and RadB (TIGR02237) and bacterial RecA (TIGR02012). It has been characterized for human as a recombinase active only in meiosis.


Pssm-ID: 131292 [Multi-domain]  Cd Length: 313  Bit Score: 45.92  E-value: 2.20e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22330951    90 RKRRVSVISTGSLNLDLALGvGGLPKGRMVEVYGKEASGKTTLAlHIIKEAQKL-------GGYCAYLDAENAMDP---- 158
Cdd:TIGR02238  71 KRKKVLKITTGSQALDGILG-GGIESMSITEVFGEFRCGKTQLS-HTLCVTAQLpremgggNGKVAYIDTEGTFRPdrir 148

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 22330951   159 SLAESIGVN----TEELLISRPSSAEKMLNIVDVL 189
Cdd:TIGR02238 149 AIAERFGVDpdavLDNILYARAYTSEHQMELLDYL 183
DMC1 cd19514
homologous-pairing protein DMC1; DMC1 has a central role in homologous recombination in ...
 97-189 2.44e-05

homologous-pairing protein DMC1; DMC1 has a central role in homologous recombination in meiosis. It assembles at the sites of programmed DNA double-strand breaks and carries out a search for allelic DNA sequences located on homologous chromatids. It forms octameric rings.


Pssm-ID: 410922 [Multi-domain]  Cd Length: 236  Bit Score: 45.04  E-value: 2.44e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22330951  97 ISTGSLNLDLALGvGGLPKGRMVEVYGKEASGKTTLAlHIIKEAQKL-------GGYCAYLDAENAMDP----SLAESIG 165
Cdd:cd19514   1 ISTGSTELDKLLG-GGIESMSITEVFGEFRTGKTQLS-HTLCVTAQLpgsmgggGGKVAYIDTEGTFRPdrirPIAERFG 78

                        90       100
                ....*....|....*....|....*...
gi 22330951 166 VNTEELL----ISRPSSAEKMLNIVDVL 189
Cdd:cd19514  79 VDHDAVLdnilYARAYTSEHQMELLDYV 106
KaiC-like cd01124
Circadian Clock Protein KaiC; KaiC is a circadian clock protein, most studied in cyanobacteria. ...
 97-149 2.94e-05

Circadian Clock Protein KaiC; KaiC is a circadian clock protein, most studied in cyanobacteria. KaiC, an autokinase, autophosphatase, and ATPase, is part of the core oscillator, composed of three proteins: KaiA, KaiB, and KaiC. The circadian oscillation is regulated via KaiC phosphorylation.


Pssm-ID: 410869 [Multi-domain]  Cd Length: 222  Bit Score: 44.95  E-value: 2.94e-05
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|...
gi 22330951  97 ISTGSLNLDLALGvGGLPKGRMVEVYGKEASGKTTLALHIIKEAQKLGGYCAY 149
Cdd:cd01124   1 VKTGIPGLDELLG-GGIPKGSVTLLTGGPGTGKTLFGLQFLYAGAKNGEPGLF 52
Rad51 cd19513
RAD51D recombinase; RAD51 recombinase plays an essential role in DNA repair by homologous ...
 97-172 7.55e-05

RAD51D recombinase; RAD51 recombinase plays an essential role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. RAD51 is recruited to the break site with the help of its paralogs, RAD51D, RAD51B, RAD51C, XRCC3, and XRCC2, where it forms long helical polymers which wrap around the ssDNA tail at the break which leads to pairing and strand invasion.


Pssm-ID: 410921 [Multi-domain]  Cd Length: 235  Bit Score: 43.85  E-value: 7.55e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22330951  97 ISTGSLNLDLALGvGGLPKGRMVEVYGKEASGKTTLAlHIIKEAQKL-------GGYCAYLDAENAMDP----SLAESIG 165
Cdd:cd19513   1 ITTGSKELDKLLG-GGIETGSITELFGEFRTGKTQLC-HTLAVTCQLpidqgggEGKALYIDTEGTFRPerllAIAERYG 78


                ....*..
gi 22330951 166 VNTEELL 172
Cdd:cd19513  79 LNGEDVL 85
PTZ00035 PTZ00035
Rad51 protein; Provisional
 89-172 8.98e-05

Rad51 protein; Provisional


Pssm-ID: 185407 [Multi-domain]  Cd Length: 337  Bit Score: 44.22  E-value: 8.98e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22330951   89 YRKRRVSV--ISTGSLNLDLALGvGGLPKGRMVEVYGKEASGKT----TLAL--HIIKEAQKLGGYCAYLDAENAMDP-- 158
Cdd:PTZ00035  90 YLEARKNIirITTGSTQLDKLLG-GGIETGSITELFGEFRTGKTqlchTLCVtcQLPIEQGGGEGKVLYIDTEGTFRPer 168

                         90
                 ....*....|....*.
gi 22330951  159 --SLAESIGVNTEELL 172
Cdd:PTZ00035 169 ivQIAERFGLDPEDVL 184
PLN03186 PLN03186
DNA repair protein RAD51 homolog; Provisional
 97-172 4.93e-04

DNA repair protein RAD51 homolog; Provisional


Pssm-ID: 178728 [Multi-domain]  Cd Length: 342  Bit Score: 41.64  E-value: 4.93e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22330951   97 ISTGSLNLDLALGvGGLPKGRMVEVYGKEASGKTTLAlHIIKEAQKLG-------GYCAYLDAENAMDP----SLAESIG 165
Cdd:PLN03186 105 ITTGSRELDKILE-GGIETGSITEIYGEFRTGKTQLC-HTLCVTCQLPldqgggeGKAMYIDTEGTFRPqrliQIAERFG 182


                 ....*..
gi 22330951  166 VNTEELL 172
Cdd:PLN03186 183 LNGADVL 189
ATPase pfam06745
KaiC; This family is in the P-loop NTPase superfamily and is found in archaea, bacteria and ...
 97-190 5.92e-04

KaiC; This family is in the P-loop NTPase superfamily and is found in archaea, bacteria and eukaryotes. More than one copy is sometimes found in each protein. This family includes KaiC, which is one of the Kai proteins among which direct protein-protein association may be a critical process in the generation of circadian rhythms in cyanobacteria.


Pssm-ID: 429095 [Multi-domain]  Cd Length: 231  Bit Score: 41.08  E-value: 5.92e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22330951    97 ISTGSLNLDLALGvGGLPKGRMVEVYGKEASGKTTLALH-IIKEAQKLGGYCAYLDAENAMDpSL---AESIGVNTEELL 172
Cdd:pfam06745   1 VKTGIPGLDEILK-GGFPEGRVVLITGGPGTGKTIFGLQfLYNGALKYGEPGVFVTLEEPPE-DLrenARSFGWDLEKLE 78

                          90
                  ....*....|....*...
gi 22330951   173 isrpssAEKMLNIVDVLT 190
Cdd:pfam06745  79 ------EEGKLAIIDAST 90
KaiC_C cd19484
C-terminal domain of Circadian Clock Protein KaiC; KaiC is a circadian clock protein, most ...
 97-179 1.01e-03

C-terminal domain of Circadian Clock Protein KaiC; KaiC is a circadian clock protein, most studied in cyanobacteria. KaiC, an autokinase, autophosphatase, and ATPase, is part of the core oscillator, composed of three proteins: KaiA, KaiB, and KaiC. The circadian oscillation is regulated via KaiC phosphorylation.


Pssm-ID: 410892 [Multi-domain]  Cd Length: 218  Bit Score: 40.00  E-value: 1.01e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22330951  97 ISTGSLNLDLALGVGGLPKGRMVEVYGKEASGKTTLALHIIKEAQKLGGYCAYLDAENAMDPSL--AESIGVNTEELLIS 174
Cdd:cd19484   1 ISTGIPRLDAMLGGGGFFRGSSILVSGATGTGKTLLAASFADAACRRGERCLYFAFEESPAQLIrnAKSIGIDLEQMERK 80

                        90
                ....*....|...
gi 22330951 175 --------RPSSA 179
Cdd:cd19484  81 gllkiicaRPELY 93
XRCC3 cd19491
XRCC3 recombinase; XRCC3 (X-ray repair complementing defective repair in Chinese hamster cells ...
 104-150 2.30e-03

XRCC3 recombinase; XRCC3 (X-ray repair complementing defective repair in Chinese hamster cells 3) recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. XRCC3, together with the other RAD51 paralogs, RAD51B, RAD51C, RAD51D, and XRCC2, helps recruit RAD51 to the break site.


Pssm-ID: 410899 [Multi-domain]  Cd Length: 250  Bit Score: 39.20  E-value: 2.30e-03
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|...
gi 22330951 104 LDLALGvGGLPKGRMVEVYGKEASGKTTLALHIIKEAQ------KLGGYCAYL 150
Cdd:cd19491   1 LDELLG-GGIPVGGITEIAGESGAGKTQLCLQLALTVQlprelgGLGGGAVYI 52
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
 115-170 3.33e-03

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 37.74  E-value: 3.33e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 22330951    115 KGRMVEVYGKEASGKTTLALHIIKEAQKLGGYCAYLDAENAMDPSLAESIGVNTEE 170
Cdd:smart00382   1 PGEVILIVGPPGSGKTTLARALARELGPPGGGVIYIDGEDILEEVLDQLLLIIVGG 56
Rad51B cd19493
RAD51B recombinase; RAD51B recombinase, a RAD51 paralog, plays an important role in DNA repair ...
 105-155 8.57e-03

RAD51B recombinase; RAD51B recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. RAD51B, together with the other RAD51 paralogs, RAD51C, RAD51D, XRCC3, and XRCC2, helps recruit RAD51 to the break site.


Pssm-ID: 410901 [Multi-domain]  Cd Length: 222  Bit Score: 37.30  E-value: 8.57e-03
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*..
gi 22330951 105 DLALGvGGLPKGRMVEVYGKEASGKTTLALHIIKEA------QKLGGYCAYLDAENA 155
Cdd:cd19493   1 DTALA-GGLPLGAITEITGASGSGKTQFALTLASSAamparkGGLDGGVLYIDTESK 56
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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