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Conserved domains on  [gi|240255275|ref|NP_187052|]
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uncharacterized protein AT3G04020 [Arabidopsis thaliana]

Protein Classification

PNPOx family protein( domain architecture ID 1004)

PNPOx family protein similar to Escherichia coli pyridoxamine 5'-phosphate oxidase (PNPOx), a FMN flavoprotein that catalyzes the oxidation of pyridoxamine-5-P (PMP) and pyridoxine-5-P (PNP) to pyridoxal-5-P (PLP)

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PNPOx/FlaRed_like super family cl00381
Pyridoxine 5'-phosphate (PNP) oxidase-like and flavin reductase-like proteins; The PNPOx-like ...
 52-119 2.97e-03

Pyridoxine 5'-phosphate (PNP) oxidase-like and flavin reductase-like proteins; The PNPOx-like superfamily is composed of pyridoxine 5'-phosphate (PNP) oxidases and other flavin mononucleotide (FMN) binding proteins, which catalyze FMN-mediated redox reactions. Flavin reductases catalyze the reduction of FMN or FAD using NAD(P)H as a cofactor. They are part of a two-component enzyme system, composed of a smaller component (flavin reductase) and a larger component (an oxidase), which uses the reduced flavin to hydroxylate substrates.


The actual alignment was detected with superfamily member pfam13883:

Pssm-ID: 469750  Cd Length: 167  Bit Score: 37.60  E-value: 2.97e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 240255275   52 GKPYLWVPESEPHNVNIMFDERGSFSIA---HPYPgplaalfKSIGKLPE-----RVAFTGEIVPVKEKRVDAVKK 119
Cdd:pfam13883  52 GNPYFLLTDLDSTVQNIQKNSRASLTLSegqTGFC-------KKHGVDPEsptcaRISLTGKLKKVESEEADFAKK 120
 
Name Accession Description Interval E-value
Pyrid_oxidase_2 pfam13883
Pyridoxamine 5'-phosphate oxidase;
52-119 2.97e-03

Pyridoxamine 5'-phosphate oxidase;


Pssm-ID: 404723  Cd Length: 167  Bit Score: 37.60  E-value: 2.97e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 240255275   52 GKPYLWVPESEPHNVNIMFDERGSFSIA---HPYPgplaalfKSIGKLPE-----RVAFTGEIVPVKEKRVDAVKK 119
Cdd:pfam13883  52 GNPYFLLTDLDSTVQNIQKNSRASLTLSegqTGFC-------KKHGVDPEsptcaRISLTGKLKKVESEEADFAKK 120
 
Name Accession Description Interval E-value
Pyrid_oxidase_2 pfam13883
Pyridoxamine 5'-phosphate oxidase;
52-119 2.97e-03

Pyridoxamine 5'-phosphate oxidase;


Pssm-ID: 404723  Cd Length: 167  Bit Score: 37.60  E-value: 2.97e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 240255275   52 GKPYLWVPESEPHNVNIMFDERGSFSIA---HPYPgplaalfKSIGKLPE-----RVAFTGEIVPVKEKRVDAVKK 119
Cdd:pfam13883  52 GNPYFLLTDLDSTVQNIQKNSRASLTLSegqTGFC-------KKHGVDPEsptcaRISLTGKLKKVESEEADFAKK 120
Phe_tRNA-synt_N pfam02912
Aminoacyl tRNA synthetase class II, N-terminal domain;
84-132 9.70e-03

Aminoacyl tRNA synthetase class II, N-terminal domain;


Pssm-ID: 460745 [Multi-domain]  Cd Length: 69  Bit Score: 34.28  E-value: 9.70e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 240255275   84 GPLAALFKSIGKLP--ERVAFtGeivpvkeKRVDAVKKYVEEAIQSEMKAI 132
Cdd:pfam02912  18 GELTALLKGLGKLPpeERPAA-G-------KLINELKQAIEAALEERKEEL 60
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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