NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|30678850|ref|NP_186994|]
View 

ARM repeat superfamily protein [Arabidopsis thaliana]

Protein Classification

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
SRP1 super family cl34886
Karyopherin (importin) alpha [Intracellular trafficking and secretion];
143-238 3.12e-05

Karyopherin (importin) alpha [Intracellular trafficking and secretion];


The actual alignment was detected with superfamily member COG5064:

Pssm-ID: 227396 [Multi-domain]  Cd Length: 526  Bit Score: 46.04  E-value: 3.12e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678850 143 IIEAGALEPIINFLQSNSPTLQEYASASLLT--LSASANNKPIIGANGVVPLLVKVIKHGSPQAKADAVMALSNLS-TLP 219
Cdd:COG5064 110 VIDAGVVPRFVEFMDEIQRDMLQFEAAWALTniASGTTQQTKVVVDAGAVPLFIQLLSSTEDDVREQAVWALGNIAgDSE 189

                        90
                ....*....|....*....
gi 30678850 220 DNLSMILATKPLSPILNLL 238
Cdd:COG5064 190 GCRDYVLQCGALEPLLGLL 208
PLN03200 super family cl33659
cellulose synthase-interactive protein; Provisional
 84-401 1.20e-04

cellulose synthase-interactive protein; Provisional


The actual alignment was detected with superfamily member PLN03200:

Pssm-ID: 215629 [Multi-domain]  Cd Length: 2102  Bit Score: 44.71  E-value: 1.20e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678850    84 AAKEIRRLTKTSHRCRR---HFSQAVEPLVSMLRFDSPEShhEAALLALLNLAVKDEKNKVSIIEAGALEPIINFLQSNS 160
Cdd:PLN03200   35 TTARLLELAKTREEARKaigSHSQAMPLLVSLLRSGTLGA--KVNAAAVLGVLCKEEDLRVKVLLGGCIPPLLSLLKSGS 112

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678850   161 PTLQEYASASLLTLSaSANNKPIIGAN-----GVVPLLVKVIKhgsPQAKADAVM------ALSNLSTLPDNL-SMILAT 228
Cdd:PLN03200  113 AEAQKAAAEAIYAVS-SGGLSDHVGSKifsteGVVPSLWDQLQ---PGNKQDKVVeglltgALRNLCGSTDGFwSATLEA 188

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678850   229 KPLSPILNLLKSSKKSSKTSEkcCSLIEALMVSGEEARTgLVSDEGGVLAVVEVLENG-SLQAREHAVGVLLTLcQSDRS 307
Cdd:PLN03200  189 GGVDILVKLLSSGNSDAQANA--ASLLARLMMAFESSIS-KVLDAGAVKQLLKLLGQGnEVSVRAEAAGALEAL-SSQSK 264

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678850   308 KYREPILREGVIPGLLELTVqGTSKSRIK---AQRL----LCLLRN---------------SESPRSEVQ-PDTIENIVS 364
Cdd:PLN03200  265 EAKQAIADAGGIPALINATV-APSKEFMQgefAQALqenaMGALANicggmsalilylgelSESPRSPAPiADTLGALAY 343

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|..
gi 30678850   365 SLISHidgDDQSGKAKKMLAEMVQVSMEKSLRH-----LQER 401
Cdd:PLN03200  344 ALMVF---DSSAESTRAFDPTVIEQILVKLLKPrdtklVQER 382
 
Name Accession Description Interval E-value
SRP1 COG5064
Karyopherin (importin) alpha [Intracellular trafficking and secretion];
143-238 3.12e-05

Karyopherin (importin) alpha [Intracellular trafficking and secretion];


Pssm-ID: 227396 [Multi-domain]  Cd Length: 526  Bit Score: 46.04  E-value: 3.12e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678850 143 IIEAGALEPIINFLQSNSPTLQEYASASLLT--LSASANNKPIIGANGVVPLLVKVIKHGSPQAKADAVMALSNLS-TLP 219
Cdd:COG5064 110 VIDAGVVPRFVEFMDEIQRDMLQFEAAWALTniASGTTQQTKVVVDAGAVPLFIQLLSSTEDDVREQAVWALGNIAgDSE 189

                        90
                ....*....|....*....
gi 30678850 220 DNLSMILATKPLSPILNLL 238
Cdd:COG5064 190 GCRDYVLQCGALEPLLGLL 208
PLN03200 PLN03200
cellulose synthase-interactive protein; Provisional
 84-401 1.20e-04

cellulose synthase-interactive protein; Provisional


Pssm-ID: 215629 [Multi-domain]  Cd Length: 2102  Bit Score: 44.71  E-value: 1.20e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678850    84 AAKEIRRLTKTSHRCRR---HFSQAVEPLVSMLRFDSPEShhEAALLALLNLAVKDEKNKVSIIEAGALEPIINFLQSNS 160
Cdd:PLN03200   35 TTARLLELAKTREEARKaigSHSQAMPLLVSLLRSGTLGA--KVNAAAVLGVLCKEEDLRVKVLLGGCIPPLLSLLKSGS 112

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678850   161 PTLQEYASASLLTLSaSANNKPIIGAN-----GVVPLLVKVIKhgsPQAKADAVM------ALSNLSTLPDNL-SMILAT 228
Cdd:PLN03200  113 AEAQKAAAEAIYAVS-SGGLSDHVGSKifsteGVVPSLWDQLQ---PGNKQDKVVeglltgALRNLCGSTDGFwSATLEA 188

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678850   229 KPLSPILNLLKSSKKSSKTSEkcCSLIEALMVSGEEARTgLVSDEGGVLAVVEVLENG-SLQAREHAVGVLLTLcQSDRS 307
Cdd:PLN03200  189 GGVDILVKLLSSGNSDAQANA--ASLLARLMMAFESSIS-KVLDAGAVKQLLKLLGQGnEVSVRAEAAGALEAL-SSQSK 264

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678850   308 KYREPILREGVIPGLLELTVqGTSKSRIK---AQRL----LCLLRN---------------SESPRSEVQ-PDTIENIVS 364
Cdd:PLN03200  265 EAKQAIADAGGIPALINATV-APSKEFMQgefAQALqenaMGALANicggmsalilylgelSESPRSPAPiADTLGALAY 343

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|..
gi 30678850   365 SLISHidgDDQSGKAKKMLAEMVQVSMEKSLRH-----LQER 401
Cdd:PLN03200  344 ALMVF---DSSAESTRAFDPTVIEQILVKLLKPrdtklVQER 382
Arm pfam00514
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ...
 136-176 2.23e-03

Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.


Pssm-ID: 425727 [Multi-domain]  Cd Length: 41  Bit Score: 35.51  E-value: 2.23e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 30678850   136 DEKNKVSIIEAGALEPIINFLQSNSPTLQEYASASLLTLSA 176
Cdd:pfam00514   1 SPENKQAVIEAGAVPPLVRLLSSPDEEVQEEAAWALSNLAA 41
PLN03200 PLN03200
cellulose synthase-interactive protein; Provisional
 138-215 5.60e-03

cellulose synthase-interactive protein; Provisional


Pssm-ID: 215629 [Multi-domain]  Cd Length: 2102  Bit Score: 39.32  E-value: 5.60e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678850   138 KNKVSIIEA-GALEPI---INFLQSNSPTLQEYASASLLTLSASAN-NKPIIGANGVVPLLVKVIKHGSPQAKADAVMAL 212
Cdd:PLN03200  433 CGKGGLWEAlGGREGVqllISLLGLSSEQQQEYAVALLAILTDEVDeSKWAITAAGGIPPLVQLLETGSQKAKEDSATVL 512


                  ...
gi 30678850   213 SNL 215
Cdd:PLN03200  513 WNL 515
 
Name Accession Description Interval E-value
SRP1 COG5064
Karyopherin (importin) alpha [Intracellular trafficking and secretion];
143-238 3.12e-05

Karyopherin (importin) alpha [Intracellular trafficking and secretion];


Pssm-ID: 227396 [Multi-domain]  Cd Length: 526  Bit Score: 46.04  E-value: 3.12e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678850 143 IIEAGALEPIINFLQSNSPTLQEYASASLLT--LSASANNKPIIGANGVVPLLVKVIKHGSPQAKADAVMALSNLS-TLP 219
Cdd:COG5064 110 VIDAGVVPRFVEFMDEIQRDMLQFEAAWALTniASGTTQQTKVVVDAGAVPLFIQLLSSTEDDVREQAVWALGNIAgDSE 189

                        90
                ....*....|....*....
gi 30678850 220 DNLSMILATKPLSPILNLL 238
Cdd:COG5064 190 GCRDYVLQCGALEPLLGLL 208
PLN03200 PLN03200
cellulose synthase-interactive protein; Provisional
 84-401 1.20e-04

cellulose synthase-interactive protein; Provisional


Pssm-ID: 215629 [Multi-domain]  Cd Length: 2102  Bit Score: 44.71  E-value: 1.20e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678850    84 AAKEIRRLTKTSHRCRR---HFSQAVEPLVSMLRFDSPEShhEAALLALLNLAVKDEKNKVSIIEAGALEPIINFLQSNS 160
Cdd:PLN03200   35 TTARLLELAKTREEARKaigSHSQAMPLLVSLLRSGTLGA--KVNAAAVLGVLCKEEDLRVKVLLGGCIPPLLSLLKSGS 112

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678850   161 PTLQEYASASLLTLSaSANNKPIIGAN-----GVVPLLVKVIKhgsPQAKADAVM------ALSNLSTLPDNL-SMILAT 228
Cdd:PLN03200  113 AEAQKAAAEAIYAVS-SGGLSDHVGSKifsteGVVPSLWDQLQ---PGNKQDKVVeglltgALRNLCGSTDGFwSATLEA 188

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678850   229 KPLSPILNLLKSSKKSSKTSEkcCSLIEALMVSGEEARTgLVSDEGGVLAVVEVLENG-SLQAREHAVGVLLTLcQSDRS 307
Cdd:PLN03200  189 GGVDILVKLLSSGNSDAQANA--ASLLARLMMAFESSIS-KVLDAGAVKQLLKLLGQGnEVSVRAEAAGALEAL-SSQSK 264

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678850   308 KYREPILREGVIPGLLELTVqGTSKSRIK---AQRL----LCLLRN---------------SESPRSEVQ-PDTIENIVS 364
Cdd:PLN03200  265 EAKQAIADAGGIPALINATV-APSKEFMQgefAQALqenaMGALANicggmsalilylgelSESPRSPAPiADTLGALAY 343

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|..
gi 30678850   365 SLISHidgDDQSGKAKKMLAEMVQVSMEKSLRH-----LQER 401
Cdd:PLN03200  344 ALMVF---DSSAESTRAFDPTVIEQILVKLLKPrdtklVQER 382
PLN03200 PLN03200
cellulose synthase-interactive protein; Provisional
 274-379 2.26e-04

cellulose synthase-interactive protein; Provisional


Pssm-ID: 215629 [Multi-domain]  Cd Length: 2102  Bit Score: 43.55  E-value: 2.26e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678850   274 GGVLAVVEVLENGSLQAREHAVGVLLTLCqSDRSKYREPILREGVIPGLLELTVQGTSKSR-IKAQRLLCLLRNSEsprs 352
Cdd:PLN03200  488 GGIPPLVQLLETGSQKAKEDSATVLWNLC-CHSEDIRACVESAGAVPALLWLLKNGGPKGQeIAAKTLTKLVRTAD---- 562

                          90       100
                  ....*....|....*....|....*..
gi 30678850   353 evqPDTIENIVSSLIshidGDDQSGKA 379
Cdd:PLN03200  563 ---AATISQLTALLL----GDLPESKV 582
PLN03200 PLN03200
cellulose synthase-interactive protein; Provisional
 158-354 1.26e-03

cellulose synthase-interactive protein; Provisional


Pssm-ID: 215629 [Multi-domain]  Cd Length: 2102  Bit Score: 41.24  E-value: 1.26e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678850   158 SNSPTLQEYASASLLTLS-ASANNKPIIGANG-VVPLLVKVIKHGSPQAKADAVMALSNLSTLPDNLSMILATKPLSPIL 235
Cdd:PLN03200   26 SSSPQEKELTTARLLELAkTREEARKAIGSHSqAMPLLVSLLRSGTLGAKVNAAAVLGVLCKEEDLRVKVLLGGCIPPLL 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678850   236 NLLKSskkssktsekccSLIEALMVSGE---EARTGLVSD---------EGGVLAVVEVLENGSLQARE---HAVGVLLT 300
Cdd:PLN03200  106 SLLKS------------GSAEAQKAAAEaiyAVSSGGLSDhvgskifstEGVVPSLWDQLQPGNKQDKVvegLLTGALRN 173

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 30678850   301 LCqSDRSKYREPILREGVIPGLLELTVQGTSKSRIKAQRLL-CLLRNSESPRSEV 354
Cdd:PLN03200  174 LC-GSTDGFWSATLEAGGVDILVKLLSSGNSDAQANAASLLaRLMMAFESSISKV 227
PLN03200 PLN03200
cellulose synthase-interactive protein; Provisional
 106-368 1.40e-03

cellulose synthase-interactive protein; Provisional


Pssm-ID: 215629 [Multi-domain]  Cd Length: 2102  Bit Score: 41.24  E-value: 1.40e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678850   106 VEPLVSMLRFDSpESHHEAALLALLNLAVKDEKNKVSIIEAGALEPIINFLQSNSPTLQEYASASLLTL-SASANNKPII 184
Cdd:PLN03200  448 VQLLISLLGLSS-EQQQEYAVALLAILTDEVDESKWAITAAGGIPPLVQLLETGSQKAKEDSATVLWNLcCHSEDIRACV 526

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678850   185 GANGVVPLLVKVIKHGSPQAKADAVMALSNL------STLPDNLSMILATKPLSP--ILNLLKSSKKSSKtsekccslIE 256
Cdd:PLN03200  527 ESAGAVPALLWLLKNGGPKGQEIAAKTLTKLvrtadaATISQLTALLLGDLPESKvhVLDVLGHVLSVAS--------LE 598

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678850   257 ALMVSGEEARTGLVSdeggvlaVVEVLENGSLQAREHAVGVLLTLCQSdRSKYREPILREGVIPGLLELTVQGTSKSRIK 336
Cdd:PLN03200  599 DLVREGSAANDALRT-------LIQLLSSSKEETQEKAASVLADIFSS-RQDLCESLATDEIINPCIKLLTNNTEAVATQ 670

                         250       260       270
                  ....*....|....*....|....*....|..
gi 30678850   337 AQRLLCLLRNSESPRSEVqPDTIENIVSSLIS 368
Cdd:PLN03200  671 SARALAALSRSIKENRKV-SYAAEDAIKPLIK 701
Arm pfam00514
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ...
 136-176 2.23e-03

Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.


Pssm-ID: 425727 [Multi-domain]  Cd Length: 41  Bit Score: 35.51  E-value: 2.23e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 30678850   136 DEKNKVSIIEAGALEPIINFLQSNSPTLQEYASASLLTLSA 176
Cdd:pfam00514   1 SPENKQAVIEAGAVPPLVRLLSSPDEEVQEEAAWALSNLAA 41
Arm_2 pfam04826
Armadillo-like; This domain contains armadillo-like repeats. Proteins containing this domain ...
 149-221 3.59e-03

Armadillo-like; This domain contains armadillo-like repeats. Proteins containing this domain interact with numerous other proteins, through these interactions they are involved in a wide variety of processes including carcinogenesis, control of cellular ageing and survival, regulation of circadian rhythm and lysosomal sorting of G protein-coupled receptors.


Pssm-ID: 461447 [Multi-domain]  Cd Length: 221  Bit Score: 38.55  E-value: 3.59e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 30678850   149 LEPIINFLQSNS-PTLQEYAsasLLTLSASAN---NKPIIGANGVVPLLVKVIKHGSPQAKADAVMALSNLSTLPDN 221
Cdd:pfam04826   6 LDKLLALLKSSEdPFIHEIA---LITLGNSAAypfNQDIIRDLGGIPIIANLLSDSNPEVKEKALNALNNLSMNVEN 79
PLN03200 PLN03200
cellulose synthase-interactive protein; Provisional
 138-215 5.60e-03

cellulose synthase-interactive protein; Provisional


Pssm-ID: 215629 [Multi-domain]  Cd Length: 2102  Bit Score: 39.32  E-value: 5.60e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678850   138 KNKVSIIEA-GALEPI---INFLQSNSPTLQEYASASLLTLSASAN-NKPIIGANGVVPLLVKVIKHGSPQAKADAVMAL 212
Cdd:PLN03200  433 CGKGGLWEAlGGREGVqllISLLGLSSEQQQEYAVALLAILTDEVDeSKWAITAAGGIPPLVQLLETGSQKAKEDSATVL 512


                  ...
gi 30678850   213 SNL 215
Cdd:PLN03200  513 WNL 515
Arm pfam00514
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ...
 177-217 7.57e-03

Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.


Pssm-ID: 425727 [Multi-domain]  Cd Length: 41  Bit Score: 33.97  E-value: 7.57e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 30678850   177 SANNKPIIGANGVVPLLVKVIKHGSPQAKADAVMALSNLST 217
Cdd:pfam00514   1 SPENKQAVIEAGAVPPLVRLLSSPDEEVQEEAAWALSNLAA 41
PLN03200 PLN03200
cellulose synthase-interactive protein; Provisional
 137-215 8.25e-03

cellulose synthase-interactive protein; Provisional


Pssm-ID: 215629 [Multi-domain]  Cd Length: 2102  Bit Score: 38.54  E-value: 8.25e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 30678850   137 EKNKVSIIEAGALEPIINFLQSNSPTLQEYASASLLTLSASANNKPIIGANGVVPLLVKVIKHGSPQAKADAVMALSNL 215
Cdd:PLN03200  684 ENRKVSYAAEDAIKPLIKLAKSSSIEVAEQAVCALANLLSDPEVAAEALAEDIILPLTRVLREGTLEGKRNAARALAQL 762
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH