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Conserved domains on  [gi|15228096|ref|NP_181255|]
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Aquaporin-like superfamily protein [Arabidopsis thaliana]

Protein Classification

MIP/aquaporin family protein( domain architecture ID 11088534)

MIP (Major Intrinsic Protein)/aquaporin family protein similar to aquaporin that permits osmotically driven movement of water in both directions, and glycerol uptake facilitator protein that mediates glycerol diffusion across the cytoplasmic membrane via a pore-type mechanism

CATH:  1.20.1080.10
Gene Ontology:  GO:0055085|GO:0015267
PubMed:  11473620|8849412|11964478
SCOP:  3000508
TCDB:  1.A.8

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
MIP pfam00230
Major intrinsic protein; MIP (Major Intrinsic Protein) family proteins exhibit essentially two ...
 29-264 1.22e-94

Major intrinsic protein; MIP (Major Intrinsic Protein) family proteins exhibit essentially two distinct types of channel properties: (1) specific water transport by the aquaporins, and (2) small neutral solutes transport, such as glycerol by the glycerol facilitators.


:

Pssm-ID: 395174 [Multi-domain]  Cd Length: 223  Bit Score: 278.43  E-value: 1.22e-94
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15228096    29 ELTKWSLYRAVIAEFVATLLFLYVTVLTVIGYKIQSDtkaggvDCGGVGILGIAWAFGGMIFILVYCTAGISGGHINPAV 108
Cdd:pfam00230   1 ELRSVSFLRAVIAEFLATLLFVFFGVGSALGVKKLVS------SLAVSGLLAVALAFGLALATLVYCAGHISGAHLNPAV 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15228096   109 TFGLFLARKVSLIRAVLYMVAQCLGAICGVGFVKAFQSShYVNYGGGANFLADGYNTGTGLAAEIIGTFVLVYTVFSATD 188
Cdd:pfam00230  75 TLALLVGRRFSLLRAIFYIVAQLLGAIAGAALLYGVTVG-LQRAGLFANTLAPGVNAGQAFVVEIILTFQLVYCVFATTD 153

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 15228096   189 PKRNARDSHVpvlAPLPIGFAVFMVHLATIPITGTGINPARSFGAAVIFNKskpWDDHWIFWVGPFIGATIAAFYH 264
Cdd:pfam00230 154 DRRNGSLGTV---APLAIGFAVFLNHLAGGPYTGASMNPARSFGPAVVLWK---WDDHWVYWVGPFIGAALGALVY 223
 
Name Accession Description Interval E-value
MIP pfam00230
Major intrinsic protein; MIP (Major Intrinsic Protein) family proteins exhibit essentially two ...
 29-264 1.22e-94

Major intrinsic protein; MIP (Major Intrinsic Protein) family proteins exhibit essentially two distinct types of channel properties: (1) specific water transport by the aquaporins, and (2) small neutral solutes transport, such as glycerol by the glycerol facilitators.


Pssm-ID: 395174 [Multi-domain]  Cd Length: 223  Bit Score: 278.43  E-value: 1.22e-94
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15228096    29 ELTKWSLYRAVIAEFVATLLFLYVTVLTVIGYKIQSDtkaggvDCGGVGILGIAWAFGGMIFILVYCTAGISGGHINPAV 108
Cdd:pfam00230   1 ELRSVSFLRAVIAEFLATLLFVFFGVGSALGVKKLVS------SLAVSGLLAVALAFGLALATLVYCAGHISGAHLNPAV 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15228096   109 TFGLFLARKVSLIRAVLYMVAQCLGAICGVGFVKAFQSShYVNYGGGANFLADGYNTGTGLAAEIIGTFVLVYTVFSATD 188
Cdd:pfam00230  75 TLALLVGRRFSLLRAIFYIVAQLLGAIAGAALLYGVTVG-LQRAGLFANTLAPGVNAGQAFVVEIILTFQLVYCVFATTD 153

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 15228096   189 PKRNARDSHVpvlAPLPIGFAVFMVHLATIPITGTGINPARSFGAAVIFNKskpWDDHWIFWVGPFIGATIAAFYH 264
Cdd:pfam00230 154 DRRNGSLGTV---APLAIGFAVFLNHLAGGPYTGASMNPARSFGPAVVLWK---WDDHWVYWVGPFIGAALGALVY 223
MIP cd00333
Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane ...
 37-267 1.97e-75

Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal cytosolic portion followed by six transmembrane helices, which might have arisen through gene duplication. On the basis of sequence similarity and functional characteristics, the superfamily can be subdivided into two major groups: water-selective channels called aquaporins (AQPs) and glycerol uptake facilitators (GlpFs). AQPs are found in all three kingdoms of life, while GlpFs have been characterized only within microorganisms.


Pssm-ID: 238204  Cd Length: 228  Bit Score: 229.83  E-value: 1.97e-75
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15228096  37 RAVIAEFVATLLFLYVTVLTVIGYKIQSDTkaggvdcgGVGILGIAWAFGGMIFILVYCTAGISGGHINPAVTFGLFLAR 116
Cdd:cd00333   1 RKYLAEFLGTFLLVFFGCGSVLAVKLAGGA--------SGGLLGIALAWGFAIFVLVYAVGHISGGHINPAVTLALAVGG 72

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15228096 117 KVSLIRAVLYMVAQCLGAICGVGFVKAFQSSHYVNYGGGANFLAD--------GYNTGTGLAAEIIGTFVLVYTVFSATD 188
Cdd:cd00333  73 RFPLIRVIPYIIAQLLGAILGAALLYGLYYGLYLEFLGANNIVAGifgtypspGVSNGNAFFVEFIGTFILVLVVFATTD 152

                       170       180       190       200       210       220       230
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 15228096 189 PKRNArdsHVPVLAPLPIGFAVFMVHLATIPITGTGINPARSFGAAVIFNKSKPWDDHWIFWVGPFIGATIAAFYHQFV 267
Cdd:cd00333 153 DPNGP---PPGGLAPLAIGLLVAAIGLAGGPITGASMNPARSLGPALFTGLARHWHYFWVYWVGPLIGAIAGALVYDYV 228
MIP TIGR00861
MIP family channel proteins; 1.A.8 The Major Intrinsic Protein (MIP) FamilyThe MIP family is ...
 41-264 2.76e-66

MIP family channel proteins; 1.A.8 The Major Intrinsic Protein (MIP) FamilyThe MIP family is large and diverse, possessing over 100 members that all form transmembrane channels. These channel proteins function in water, smallcarbohydrate (e.g., glycerol), urea, NH3, CO2 and possibly ion transport by an energy independent mechanism. They are found ubiquitously in bacteria, archaeaand eukaryotes. The MIP family contains two major groups of channels: aquaporins and glycerol facilitators.The known aquaporins cluster loosely together as do the known glycerol facilitators. MIP family proteins are believed to form aqueous pores that selectively allow passive transport of their solute(s) across the membrane with minimal apparent recognition. Aquaporins selectively transport water (but not glycerol) while glycerol facilitators selectively transport glycerol but not water. Some aquaporins can transport NH3 and CO2. Glycerol facilitators function as solute nonspecific channels, and may transport glycerol, dihydroxyacetone, propanediol, urea and other small neutral molecules in physiologically importantprocesses. Some members of the family, including the yeast FPS protein (TC #1.A.8.5.1) and tobacco NtTIPA may transport both water and small solutes. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 273306 [Multi-domain]  Cd Length: 216  Bit Score: 206.00  E-value: 2.76e-66
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15228096    41 AEFVATLLFLYVTVLTVIGYKIQSDTKAGGvdcgGVGILGIAWAFGGMIFILVYCTAGISGGHINPAVTFGLFLARKVSL 120
Cdd:TIGR00861   1 AEFLGTFLLVFFGVGSALGVNVAGAYGAVG----GGQFLGVALAFGLAVATLVYCVGGISGAHLNPAVTIALLLGRRFPL 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15228096   121 IRAVLYMVAQCLGAICGVGFVKAFQSSHYVNYGGGANFLADGYNTGTGLAAEIIGTFVLVYTVFSATDpKRNARDSHvpV 200
Cdd:TIGR00861  77 KRVPVYIVAQLIGAILGAALLYGLTSGLFPGNLAVNGSASAGVSSGQAFFVEFIGTAILVLVIFATTD-DRNRVPRG--G 153

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 15228096   201 LAPLPIGFAVFMVHLATIPITGTGINPARSFGAAVIFNKSkPWDDHWIFWVGPFIGATIAAFYH 264
Cdd:TIGR00861 154 FAPLAIGLLVFLIHLSMGPYTGTGMNPARSLGPALFAGLA-GWGNHWVYWVGPIIGAILGALVY 216
GlpF COG0580
Glycerol uptake facilitator or related aquaporin (Major Intrinsic protein Family) ...
 34-269 4.42e-57

Glycerol uptake facilitator or related aquaporin (Major Intrinsic protein Family) [Carbohydrate transport and metabolism];


Pssm-ID: 440345 [Multi-domain]  Cd Length: 232  Bit Score: 183.02  E-value: 4.42e-57
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15228096  34 SLYRAVIAEFVAT--LLFLYVTVLTVIgykiqSDTKaggvdcGGVGILGIAWAFGGMIFILVYCTAGISGGHINPAVTFG 111
Cdd:COG0580   1 SLMKRLLAEFLGTfiLVLLGCGVVAVL-----AGTK------GGIGWLGIALAWGLAVLAGVYAFGHISGAHLNPAVTLA 69

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15228096 112 LFLARKVSLIRAVLYMVAQCLGAICGVGFVKAFQSSHYVNYGGG-------ANFLADGYNTGTGLAAEIIGTFVLVYTVF 184
Cdd:COG0580  70 LAVAGRFPWKDVLPYIIAQLLGAFLGAALVYLIYGGHFDATEDGgaklgvfATSPAIGYSLGAAFLTEIIGTFVLVFVIL 149

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15228096 185 SATDPKRNARdshvpVLAPLPIGFAVFMVHLATIPITGTGINPARSFG---AAVIFNKSKPWDDHWIFWVGPFIGATIAA 261
Cdd:COG0580 150 GITDKRAAPG-----GLAPLAIGLLVAAIGLSLGPLTGYAINPARDLGprlFHALGKGGSDWGYLWVPIVAPILGAALAA 224


                ....*...
gi 15228096 262 FYHQFVLR 269
Cdd:COG0580 225 LLYRALFG 232
PLN00166 PLN00166
aquaporin TIP2; Provisional
 37-264 4.80e-38

aquaporin TIP2; Provisional


Pssm-ID: 165733  Cd Length: 250  Bit Score: 134.68  E-value: 4.80e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15228096   37 RAVIAEFVATLLFLYVTVLTVIGY-KIQSDtkaGGVDCGGVGILGIAWAFGgmIFILVYCTAGISGGHINPAVTFGLFLA 115
Cdd:PLN00166  19 KAYLSEFIATLLFVFAGVGSAIAFaKLTSD---AALDPAGLVAVAVAHAFA--LFVGVSIAANISGGHLNPAVTLGLAIG 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15228096  116 RKVSLIRAVLYMVAQCLGAICGVGFVKAFQSSHYVNYGGganfLADGYNTGTGLAAEIIGTFVLVYTVF-SATDPKRNAr 194
Cdd:PLN00166  94 GNITIITGFFYWIAQCLGSIVACLLLVFVTNGESVPTHG----VAAGLGAIEGVVMEIVVTFALVYTVYaTAADPKKGS- 168

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15228096  195 dshVPVLAPLPIGFAVFMVHLATIPITGTGINPARSFGAAVIfnkSKPWDDHWIFWVGPFIGATIAAFYH 264
Cdd:PLN00166 169 ---LGTIAPIAIGFIVGANILAAGPFSGGSMNPARSFGPAVV---SGDFSQIWIYWVGPLVGGALAGLIY 232
 
Name Accession Description Interval E-value
MIP pfam00230
Major intrinsic protein; MIP (Major Intrinsic Protein) family proteins exhibit essentially two ...
 29-264 1.22e-94

Major intrinsic protein; MIP (Major Intrinsic Protein) family proteins exhibit essentially two distinct types of channel properties: (1) specific water transport by the aquaporins, and (2) small neutral solutes transport, such as glycerol by the glycerol facilitators.


Pssm-ID: 395174 [Multi-domain]  Cd Length: 223  Bit Score: 278.43  E-value: 1.22e-94
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15228096    29 ELTKWSLYRAVIAEFVATLLFLYVTVLTVIGYKIQSDtkaggvDCGGVGILGIAWAFGGMIFILVYCTAGISGGHINPAV 108
Cdd:pfam00230   1 ELRSVSFLRAVIAEFLATLLFVFFGVGSALGVKKLVS------SLAVSGLLAVALAFGLALATLVYCAGHISGAHLNPAV 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15228096   109 TFGLFLARKVSLIRAVLYMVAQCLGAICGVGFVKAFQSShYVNYGGGANFLADGYNTGTGLAAEIIGTFVLVYTVFSATD 188
Cdd:pfam00230  75 TLALLVGRRFSLLRAIFYIVAQLLGAIAGAALLYGVTVG-LQRAGLFANTLAPGVNAGQAFVVEIILTFQLVYCVFATTD 153

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 15228096   189 PKRNARDSHVpvlAPLPIGFAVFMVHLATIPITGTGINPARSFGAAVIFNKskpWDDHWIFWVGPFIGATIAAFYH 264
Cdd:pfam00230 154 DRRNGSLGTV---APLAIGFAVFLNHLAGGPYTGASMNPARSFGPAVVLWK---WDDHWVYWVGPFIGAALGALVY 223
MIP cd00333
Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane ...
 37-267 1.97e-75

Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal cytosolic portion followed by six transmembrane helices, which might have arisen through gene duplication. On the basis of sequence similarity and functional characteristics, the superfamily can be subdivided into two major groups: water-selective channels called aquaporins (AQPs) and glycerol uptake facilitators (GlpFs). AQPs are found in all three kingdoms of life, while GlpFs have been characterized only within microorganisms.


Pssm-ID: 238204  Cd Length: 228  Bit Score: 229.83  E-value: 1.97e-75
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15228096  37 RAVIAEFVATLLFLYVTVLTVIGYKIQSDTkaggvdcgGVGILGIAWAFGGMIFILVYCTAGISGGHINPAVTFGLFLAR 116
Cdd:cd00333   1 RKYLAEFLGTFLLVFFGCGSVLAVKLAGGA--------SGGLLGIALAWGFAIFVLVYAVGHISGGHINPAVTLALAVGG 72

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15228096 117 KVSLIRAVLYMVAQCLGAICGVGFVKAFQSSHYVNYGGGANFLAD--------GYNTGTGLAAEIIGTFVLVYTVFSATD 188
Cdd:cd00333  73 RFPLIRVIPYIIAQLLGAILGAALLYGLYYGLYLEFLGANNIVAGifgtypspGVSNGNAFFVEFIGTFILVLVVFATTD 152

                       170       180       190       200       210       220       230
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 15228096 189 PKRNArdsHVPVLAPLPIGFAVFMVHLATIPITGTGINPARSFGAAVIFNKSKPWDDHWIFWVGPFIGATIAAFYHQFV 267
Cdd:cd00333 153 DPNGP---PPGGLAPLAIGLLVAAIGLAGGPITGASMNPARSLGPALFTGLARHWHYFWVYWVGPLIGAIAGALVYDYV 228
MIP TIGR00861
MIP family channel proteins; 1.A.8 The Major Intrinsic Protein (MIP) FamilyThe MIP family is ...
 41-264 2.76e-66

MIP family channel proteins; 1.A.8 The Major Intrinsic Protein (MIP) FamilyThe MIP family is large and diverse, possessing over 100 members that all form transmembrane channels. These channel proteins function in water, smallcarbohydrate (e.g., glycerol), urea, NH3, CO2 and possibly ion transport by an energy independent mechanism. They are found ubiquitously in bacteria, archaeaand eukaryotes. The MIP family contains two major groups of channels: aquaporins and glycerol facilitators.The known aquaporins cluster loosely together as do the known glycerol facilitators. MIP family proteins are believed to form aqueous pores that selectively allow passive transport of their solute(s) across the membrane with minimal apparent recognition. Aquaporins selectively transport water (but not glycerol) while glycerol facilitators selectively transport glycerol but not water. Some aquaporins can transport NH3 and CO2. Glycerol facilitators function as solute nonspecific channels, and may transport glycerol, dihydroxyacetone, propanediol, urea and other small neutral molecules in physiologically importantprocesses. Some members of the family, including the yeast FPS protein (TC #1.A.8.5.1) and tobacco NtTIPA may transport both water and small solutes. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 273306 [Multi-domain]  Cd Length: 216  Bit Score: 206.00  E-value: 2.76e-66
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15228096    41 AEFVATLLFLYVTVLTVIGYKIQSDTKAGGvdcgGVGILGIAWAFGGMIFILVYCTAGISGGHINPAVTFGLFLARKVSL 120
Cdd:TIGR00861   1 AEFLGTFLLVFFGVGSALGVNVAGAYGAVG----GGQFLGVALAFGLAVATLVYCVGGISGAHLNPAVTIALLLGRRFPL 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15228096   121 IRAVLYMVAQCLGAICGVGFVKAFQSSHYVNYGGGANFLADGYNTGTGLAAEIIGTFVLVYTVFSATDpKRNARDSHvpV 200
Cdd:TIGR00861  77 KRVPVYIVAQLIGAILGAALLYGLTSGLFPGNLAVNGSASAGVSSGQAFFVEFIGTAILVLVIFATTD-DRNRVPRG--G 153

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 15228096   201 LAPLPIGFAVFMVHLATIPITGTGINPARSFGAAVIFNKSkPWDDHWIFWVGPFIGATIAAFYH 264
Cdd:TIGR00861 154 FAPLAIGLLVFLIHLSMGPYTGTGMNPARSLGPALFAGLA-GWGNHWVYWVGPIIGAILGALVY 216
GlpF COG0580
Glycerol uptake facilitator or related aquaporin (Major Intrinsic protein Family) ...
 34-269 4.42e-57

Glycerol uptake facilitator or related aquaporin (Major Intrinsic protein Family) [Carbohydrate transport and metabolism];


Pssm-ID: 440345 [Multi-domain]  Cd Length: 232  Bit Score: 183.02  E-value: 4.42e-57
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15228096  34 SLYRAVIAEFVAT--LLFLYVTVLTVIgykiqSDTKaggvdcGGVGILGIAWAFGGMIFILVYCTAGISGGHINPAVTFG 111
Cdd:COG0580   1 SLMKRLLAEFLGTfiLVLLGCGVVAVL-----AGTK------GGIGWLGIALAWGLAVLAGVYAFGHISGAHLNPAVTLA 69

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15228096 112 LFLARKVSLIRAVLYMVAQCLGAICGVGFVKAFQSSHYVNYGGG-------ANFLADGYNTGTGLAAEIIGTFVLVYTVF 184
Cdd:COG0580  70 LAVAGRFPWKDVLPYIIAQLLGAFLGAALVYLIYGGHFDATEDGgaklgvfATSPAIGYSLGAAFLTEIIGTFVLVFVIL 149

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15228096 185 SATDPKRNARdshvpVLAPLPIGFAVFMVHLATIPITGTGINPARSFG---AAVIFNKSKPWDDHWIFWVGPFIGATIAA 261
Cdd:COG0580 150 GITDKRAAPG-----GLAPLAIGLLVAAIGLSLGPLTGYAINPARDLGprlFHALGKGGSDWGYLWVPIVAPILGAALAA 224


                ....*...
gi 15228096 262 FYHQFVLR 269
Cdd:COG0580 225 LLYRALFG 232
PLN00166 PLN00166
aquaporin TIP2; Provisional
 37-264 4.80e-38

aquaporin TIP2; Provisional


Pssm-ID: 165733  Cd Length: 250  Bit Score: 134.68  E-value: 4.80e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15228096   37 RAVIAEFVATLLFLYVTVLTVIGY-KIQSDtkaGGVDCGGVGILGIAWAFGgmIFILVYCTAGISGGHINPAVTFGLFLA 115
Cdd:PLN00166  19 KAYLSEFIATLLFVFAGVGSAIAFaKLTSD---AALDPAGLVAVAVAHAFA--LFVGVSIAANISGGHLNPAVTLGLAIG 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15228096  116 RKVSLIRAVLYMVAQCLGAICGVGFVKAFQSSHYVNYGGganfLADGYNTGTGLAAEIIGTFVLVYTVF-SATDPKRNAr 194
Cdd:PLN00166  94 GNITIITGFFYWIAQCLGSIVACLLLVFVTNGESVPTHG----VAAGLGAIEGVVMEIVVTFALVYTVYaTAADPKKGS- 168

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15228096  195 dshVPVLAPLPIGFAVFMVHLATIPITGTGINPARSFGAAVIfnkSKPWDDHWIFWVGPFIGATIAAFYH 264
Cdd:PLN00166 169 ---LGTIAPIAIGFIVGANILAAGPFSGGSMNPARSFGPAVV---SGDFSQIWIYWVGPLVGGALAGLIY 232
PLN00027 PLN00027
aquaporin TIP; Provisional
 28-273 1.37e-36

aquaporin TIP; Provisional


Pssm-ID: 177664  Cd Length: 252  Bit Score: 130.68  E-value: 1.37e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15228096   28 EELTKWSLYRAVIAEFVATLLFLYVTVLTVIGY-KIQSDtkaGGVDCGGVGILGIAWAFGgmIFILVYCTAGISGGHINP 106
Cdd:PLN00027  12 GEASHPDALKAALAEFISTLIFVFAGEGSGMAFnKLTDN---GSTTPAGLVAAALAHAFA--LFVAVSVGANISGGHVNP 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15228096  107 AVTFGLFLARKVSLIRAVLYMVAQCLGAICGVGFVKAfqSSHYVNYGGGAnfLADGYNTGTGLAAEIIGTFVLVYTVF-S 185
Cdd:PLN00027  87 AVTFGAFIGGNITLLRGILYWIAQLLGSVVACLLLKF--STGGLETSAFS--LSSGVGVWNAFVFEIVMTFGLVYTVYaT 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15228096  186 ATDPKRnardSHVPVLAPLPIGFAVFMVHLATIPITGTGINPARSFGAAVIfnkSKPWDDHWIFWVGPFIGATIAAFYHQ 265
Cdd:PLN00027 163 AVDPKK----GDLGIIAPIAIGFIVGANILAGGAFDGASMNPAVSFGPAVV---SWTWTNHWVYWAGPLIGGGIAGLVYE 235


                 ....*...
gi 15228096  266 FVLRASGS 273
Cdd:PLN00027 236 LIFIGSTT 243
PRK05420 PRK05420
aquaporin Z; Provisional
 75-268 6.76e-33

aquaporin Z; Provisional


Pssm-ID: 235453 [Multi-domain]  Cd Length: 231  Bit Score: 120.46  E-value: 6.76e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15228096   75 GVGILGIAWAFGGMIFILVYCTAGISGGHINPAVTFGLFLARKVSLIRAVLYMVAQCLGAICGVGFVKAFQSSHYVNYGG 154
Cdd:PRK05420  33 GIGFLGVALAFGLTVLTMAYAVGHISGGHFNPAVSVGLWAGGRFPAKELVPYIIAQVVGGIAAAAVLYLIASGKAGFDLA 112

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15228096  155 GANFLADG--------YNTGTGLAAEIIGTFVLVYTVFSATdpkrnarDSHVPV-LAPLPIGFAVFMVHLATIPITGTGI 225
Cdd:PRK05420 113 GSGFASNGygehspggYSLLAALVCEVVLTAFFLLVILGAT-------DKRAPAgFAPIAIGLALTLIHLISIPVTNTSV 185

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 15228096  226 NPARSFGAAvIFNKSKPWDDHWIFWVGPFIGATIAAFYHQFVL 268
Cdd:PRK05420 186 NPARSTGVA-LFVGGWALEQLWLFWVAPIVGAIIGGLIYRLLL 227
PLN00167 PLN00167
aquaporin TIP5; Provisional
 37-268 4.57e-28

aquaporin TIP5; Provisional


Pssm-ID: 215085  Cd Length: 256  Bit Score: 108.45  E-value: 4.57e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15228096   37 RAVIAEFVATLLFLYVTVLTVIGY-KIQSDTKAggvDCGGVGILGIAWAFGgmIFILVYCTAGISGGHINPAVTFGLFLA 115
Cdd:PLN00167  23 RSYLAEFISTFFFVFAAVGSAMSSrKLMPDAAS---DPSSLLIVAIANAFA--LSSAVYIAANISGGHVNPAVTFGMAVG 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15228096  116 RKVSLIRAVLYMVAQCLGAICGVGFVKAFQSSHYVnygggANFLADGYNTGTGLAA-EIIGTFVLVYTVFSATDPKRnar 194
Cdd:PLN00167  98 GHISVPTAMFYWISQMLASVMACLFLKVTTVGQHV-----PTYKIAEEMTGFGASVlEGVLTFGLVYTVYAAGDPRR--- 169

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 15228096  195 dSHVPVLAPLPIGFAVFMVHLATIPITGTGINPARSFGAAVIFNKSKpwdDHWIFWVGPFIGATIAAFYHQFVL 268
Cdd:PLN00167 170 -GLLGAIGPLAIGLVAGANVLAAGPFSGGSMNPACAFGSAVVAGSFK---NQAVYWVGPLLGGAVAGLLYDNVV 239
PTZ00016 PTZ00016
aquaglyceroporin; Provisional
 12-268 9.34e-20

aquaglyceroporin; Provisional


Pssm-ID: 240230 [Multi-domain]  Cd Length: 294  Bit Score: 86.72  E-value: 9.34e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15228096   12 QTRDYEDPPPTPFFDAEELTKWslYRAVIAEFVATLlflyvtVLTVIGYKIQSDTKAGGVDCGGVGILgIAWAFGgmIFI 91
Cdd:PTZ00016  28 AEAQKRPPGGQNFWAPREYRPN--VREYVAEFLGTF------VLLFFGEGVVATTHTVGNNGDYLAIT-IGWGLG--VTF 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15228096   92 LVYCTAGISGGHINPAVTFGLFLARKVSLIRAVLYMVAQCLGAICGVGFVKAFQSSHYVNYGGG--ANFLADGYNTG--- 166
Cdd:PTZ00016  97 GLLVSAGISGGHLNPAVTLGNAVFGKFPWKKLPGYFVAQLLGAFVGAACVYGLYYGFFKDHGIPelPWETMANGFAGvfa 176

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15228096  167 --------TGLAAEIIGTFVLVYTVFSATDPKRNARDSHVPVlaplPIGFAVFMVHLATIPITGTGINPARSFGA----A 234
Cdd:PTZ00016 177 typregnfYAIFSELILTAILLLVILAITDPNNCPAFNYLPV----AVGLLVFVIGISFGGNTGYALNPARDLGPrlfsA 252

                        250       260       270
                 ....*....|....*....|....*....|....*..
gi 15228096  235 VIFNKSKPWDDHWIFW---VGPFIGATIAAFYHQFVL 268
Cdd:PTZ00016 253 ILWGSEVFTKDNYYFWvplVAPFVGAVLGMFLYDKFI 289
PLN00183 PLN00183
putative aquaporin NIP7; Provisional
 37-269 5.77e-18

putative aquaporin NIP7; Provisional


Pssm-ID: 215092  Cd Length: 274  Bit Score: 81.44  E-value: 5.77e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15228096   37 RAVIAEFVATLLFLYVTvltvigYKIQSDTKAGGvdcGGVGILGIAWAFGGMIFILVYCTAGISGGHINPAVT-----FG 111
Cdd:PLN00183  46 RMVLAEMVGTFILMFCV------CGIIASTQLSG---GEVGLLEYAATAGLTVVVVVFSIGSISGAHVNPSVTiafatFG 116

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15228096  112 LFLARKVSliravLYMVAQCLGAIcgvgfvkafqSSHYVN---YGGGANFLADGYNTGTGLA--AEIIGTFVLVYTVFSA 186
Cdd:PLN00183 117 HFPWSKVP-----LYITAQTVGSV----------LATYVGvsvYGVKADLMTTKPAQGCSSAfwVEFIATFIVMFLAASL 181

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15228096  187 TDPKRNARDshvpvLAPLPIGFAVFMVHLATIPITGTGINPARSFGAAVIfnkSKPWDDHWIFWVGPFIGATIAAF-YHQ 265
Cdd:PLN00183 182 TSQPQSLGH-----LSGFVIGIAIGLAVLITGPVSGGSMNPARSLGPAIV---SWDFKDIWIYITAPTIGAVAGALmFHL 253


                 ....
gi 15228096  266 FVLR 269
Cdd:PLN00183 254 LRLR 257
PLN00182 PLN00182
putative aquaporin NIP4; Provisional
 74-267 6.56e-17

putative aquaporin NIP4; Provisional


Pssm-ID: 165748  Cd Length: 283  Bit Score: 78.80  E-value: 6.56e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15228096   74 GGVGILGIAWAFGGMIFILVYCTAGISGGHINPAVTFGLFLARKVSLIRAVLYMVAQCLGAICGVGFVK-AFQSSHYVNY 152
Cdd:PLN00182  71 GTITFPGICVTWGLIVMVMIYSTGHISGAHFNPAVTVTFAIFRRFPWYQVPLYIGAQLTGSLLASLTLRlMFNVTPEAFF 150

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15228096  153 GgganfLADGYNTGTGLAAEIIGTFVLVYTVFSATDPKRNARDshvpvLAPLPIGFAVFMVHLATIPITGTGINPARSFG 232
Cdd:PLN00182 151 G-----TTPTDSSGQALVAEIIISFLLMFVISGVATDSRAVGE-----LAGIAVGMTIILNVFVAGPISGASMNPARSLG 220

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 15228096  233 AAVIFNKSKpwdDHWIFWVGPFIGATIAAFYHQFV 267
Cdd:PLN00182 221 PAIVMGRYK---GIWVYIVGPFVGIIAGGFVYNLI 252
PLN00026 PLN00026
aquaporin NIP; Provisional
 34-261 3.94e-16

aquaporin NIP; Provisional


Pssm-ID: 177663 [Multi-domain]  Cd Length: 298  Bit Score: 76.82  E-value: 3.94e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15228096   34 SLYRAVIAEFVATLLFLYVTVLTVIgykiqSDTKAGGVDCggvgILGIAWAFGGMIFILVYCTAGISGGHINPAVTFGLF 113
Cdd:PLN00026  69 SLTRKLGAEFVGTFILIFAATAGPI-----VNQKYDGAET----LIGNAACAGLAVMIVILSTGHISGAHLNPSLTIAFA 139

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15228096  114 LARKVSLIRAVLYMVAQCLGAICGvGFvkAFQSSHYVNYGGGANFLADGynTGTGLAAEIIGTFVLVYTVFS-ATDPKRn 192
Cdd:PLN00026 140 ALRHFPWKHVPAYIAAQVSASICA-SF--ALKGVFHPFMSGGVTVPSVS--TGQAFALEFIITFNLLFVVTAvATDTRA- 213

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 15228096  193 ardshVPVLAPLPIGFAVFMVHLATIPITGTGINPARSFGAAVIFNKSKpwdDHWIFWVGPFIGATIAA 261
Cdd:PLN00026 214 -----VGELAGIAVGATVMLNILVAGPSTGGSMNPVRTLGPAVAAGNYR---AIWIYLVAPTLGALAGA 274
PLN00184 PLN00184
aquaporin NIP1; Provisional
 12-267 6.27e-16

aquaporin NIP1; Provisional


Pssm-ID: 177778  Cd Length: 296  Bit Score: 76.21  E-value: 6.27e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15228096   12 QTRDYEDPPPTPFFDAEELTKWSLYRAVIAEFVATLlFLYVTVLTVIGYKIQSDTkaggvdcgGVGILGIAWAFGGMIFI 91
Cdd:PLN00184  30 EMEAIHNPKPLKKQDSLLSVSVPFLQKLIAEVLGTY-FLVFTGCASVVVNMQNDN--------VVTLPGIAIVWGLTIMV 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15228096   92 LVYCTAGISGGHINPAVTFGLFLARKVSLIRAVLYMVAQCLGAICGVGFVK-AFQSSHYVNYGGGANFLADgYNTGTGLA 170
Cdd:PLN00184 101 LIYSLGHISGAHINPAVTIAFASCGRFPLKQVPAYVISQVIGSTLAAATLRlLFGLDHDVCSGKHDVFIGS-SPVGSDLQ 179

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15228096  171 A---EIIGTFVLVYTVFS-ATDpkrnarDSHVPVLAPLPIGFAVFMVHLATIPITGTGINPARSFGAAVIFNKSKPWddh 246
Cdd:PLN00184 180 AfvmEFIVTFYLMFIISGvATD------NRAIGELAGLAIGSTVLLNVLIAAPVSSASMNPGRSLGPAMVYGCYKGI--- 250

                        250       260
                 ....*....|....*....|.
gi 15228096  247 WIFWVGPFIGATIAAFYHQFV 267
Cdd:PLN00184 251 WIYIVAPTLGAIAGAWVYNTV 271
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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