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Conserved domains on  [gi|15227980|ref|NP_181186|]
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Integrase-type DNA-binding superfamily protein [Arabidopsis thaliana]

Protein Classification

AP2/ERF family transcription factor( domain architecture ID 10647620)

AP2/ERF family transcription factor binds to the GCC-box pathogenesis-related promoter element; similar to Arabidopsis thaliana ethylene-responsive transcription factors and dehydration-responsive element-binding proteins

Gene Ontology:  GO:0003700|GO:0006952
PubMed:  24010138|32522044

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
AP2 smart00380
DNA-binding domain in plant proteins such as APETALA2 and EREBPs;
15-74 1.71e-30

DNA-binding domain in plant proteins such as APETALA2 and EREBPs;


:

Pssm-ID: 197689  Cd Length: 64  Bit Score: 105.81  E-value: 1.71e-30
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 15227980     15 YRGVRQRKNSnKWVSEIREPRKPNRIWLGTFSTPEMAAIAYDVAALALKGSQAELNFPNS 74
Cdd:smart00380   2 YRGVRQRPWG-KWVAEIRDPSKGKRVWLGTFDTAEEAARAYDRAAFKFRGRSARLNFPNS 60
 
Name Accession Description Interval E-value
AP2 smart00380
DNA-binding domain in plant proteins such as APETALA2 and EREBPs;
15-74 1.71e-30

DNA-binding domain in plant proteins such as APETALA2 and EREBPs;


Pssm-ID: 197689  Cd Length: 64  Bit Score: 105.81  E-value: 1.71e-30
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 15227980     15 YRGVRQRKNSnKWVSEIREPRKPNRIWLGTFSTPEMAAIAYDVAALALKGSQAELNFPNS 74
Cdd:smart00380   2 YRGVRQRPWG-KWVAEIRDPSKGKRVWLGTFDTAEEAARAYDRAAFKFRGRSARLNFPNS 60
AP2 cd00018
DNA-binding domain found in transcription regulators in plants such as APETALA2 and EREBP ...
 13-74 1.37e-29

DNA-binding domain found in transcription regulators in plants such as APETALA2 and EREBP (ethylene responsive element binding protein). In EREBPs the domain specifically binds to the 11bp GCC box of the ethylene response element (ERE), a promotor element essential for ethylene responsiveness. EREBPs and the C-repeat binding factor CBF1, which is involved in stress response, contain a single copy of the AP2 domain. APETALA2-like proteins, which play a role in plant development contain two copies.


Pssm-ID: 237985  Cd Length: 61  Bit Score: 103.51  E-value: 1.37e-29
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 15227980  13 PLYRGVRQRKNSnKWVSEIREPRKPNRIWLGTFSTPEMAAIAYDVAALALKGSQAELNFPNS 74
Cdd:cd00018   1 SKYRGVRQRPWG-KWVAEIRDPSGGRRIWLGTFDTAEEAARAYDRAALKLRGSSAVLNFPDS 61
AP2 pfam00847
AP2 domain; This 60 amino acid residue domain can bind to DNA and is found in transcription ...
 15-64 2.13e-11

AP2 domain; This 60 amino acid residue domain can bind to DNA and is found in transcription factor proteins.


Pssm-ID: 425904  Cd Length: 52  Bit Score: 56.49  E-value: 2.13e-11
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 15227980    15 YRGVRQRKNSNKWVSEIRE--PRKPNRIWLGTFSTpEMAAIAYDVAALALKG 64
Cdd:pfam00847   2 IRGVRYDKKWGRWVAEWSEngKRRKKRFSLGKYGT-EEAKRAAIEARKKLEG 52
 
Name Accession Description Interval E-value
AP2 smart00380
DNA-binding domain in plant proteins such as APETALA2 and EREBPs;
15-74 1.71e-30

DNA-binding domain in plant proteins such as APETALA2 and EREBPs;


Pssm-ID: 197689  Cd Length: 64  Bit Score: 105.81  E-value: 1.71e-30
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 15227980     15 YRGVRQRKNSnKWVSEIREPRKPNRIWLGTFSTPEMAAIAYDVAALALKGSQAELNFPNS 74
Cdd:smart00380   2 YRGVRQRPWG-KWVAEIRDPSKGKRVWLGTFDTAEEAARAYDRAAFKFRGRSARLNFPNS 60
AP2 cd00018
DNA-binding domain found in transcription regulators in plants such as APETALA2 and EREBP ...
 13-74 1.37e-29

DNA-binding domain found in transcription regulators in plants such as APETALA2 and EREBP (ethylene responsive element binding protein). In EREBPs the domain specifically binds to the 11bp GCC box of the ethylene response element (ERE), a promotor element essential for ethylene responsiveness. EREBPs and the C-repeat binding factor CBF1, which is involved in stress response, contain a single copy of the AP2 domain. APETALA2-like proteins, which play a role in plant development contain two copies.


Pssm-ID: 237985  Cd Length: 61  Bit Score: 103.51  E-value: 1.37e-29
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 15227980  13 PLYRGVRQRKNSnKWVSEIREPRKPNRIWLGTFSTPEMAAIAYDVAALALKGSQAELNFPNS 74
Cdd:cd00018   1 SKYRGVRQRPWG-KWVAEIRDPSGGRRIWLGTFDTAEEAARAYDRAALKLRGSSAVLNFPDS 61
AP2 pfam00847
AP2 domain; This 60 amino acid residue domain can bind to DNA and is found in transcription ...
 15-64 2.13e-11

AP2 domain; This 60 amino acid residue domain can bind to DNA and is found in transcription factor proteins.


Pssm-ID: 425904  Cd Length: 52  Bit Score: 56.49  E-value: 2.13e-11
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 15227980    15 YRGVRQRKNSNKWVSEIRE--PRKPNRIWLGTFSTpEMAAIAYDVAALALKG 64
Cdd:pfam00847   2 IRGVRYDKKWGRWVAEWSEngKRRKKRFSLGKYGT-EEAKRAAIEARKKLEG 52
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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