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Conserved domains on  [gi|79567911|ref|NP_181143|]
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Putative lysine decarboxylase family protein [Arabidopsis thaliana]

Protein Classification

LOG family protein( domain architecture ID 10004058)

LOG (Lonely Guy) family protein similar to Arabidopsis thaliana cytokinin riboside 5'-monophosphate phosphoribohydrolases, which are cytokinin-activating enzymes working in the direct activation pathway, converting inactive cytokinin nucleotides to the biologically active free-base forms

CATH:  3.40.50.450
EC:  3.2.2.-
Gene Ontology:  GO:0016799|GO:0009691
PubMed:  29525484
SCOP:  4001074

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PpnN COG1611
Nucleotide monophosphate nucleosidase PpnN/YdgH, Lonely Guy (LOG) family [Nucleotide transport ...
10-192 3.10e-81

Nucleotide monophosphate nucleosidase PpnN/YdgH, Lonely Guy (LOG) family [Nucleotide transport and metabolism];


:

Pssm-ID: 441219  Cd Length: 184  Bit Score: 240.01  E-value: 3.10e-81
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79567911  10 RICVFCGSSSGNKTTYHDAALQLAHQLVERNIDLVYGGGSVGLMGLISQAVHDGGRHVLGIIPKSLAPREITGESIGEVI 89
Cdd:COG1611   1 SVCVFGGSRTGPDPPYYEAARELGRLLAERGFTLVTGGGPVGLMGAVADGALEAGGRSIGVIPHFLVEREVANPYLTELI 80
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79567911  90 TVSTMHQRKAEMGRQADAFIALPGGYGTFEELLEVITWSQLGIHTKPVGLLNVDGFYDSLLTFIDKAVDEGFVSSTARRI 169
Cdd:COG1611  81 VVDYMHERKAMMLELADAFVALPGGFGTLDELFEVLTLAQLGKHPKPIVLLNGNGFWDPLLDWLDHMLEEGFISPEDLDL 160
                       170       180
                ....*....|....*....|...
gi 79567911 170 IVSAPNAPQLLQLLEEYVPKHDD 192
Cdd:COG1611 161 LLVVDDPEEALDALEAYEPPYAS 183
 
Name Accession Description Interval E-value
PpnN COG1611
Nucleotide monophosphate nucleosidase PpnN/YdgH, Lonely Guy (LOG) family [Nucleotide transport ...
10-192 3.10e-81

Nucleotide monophosphate nucleosidase PpnN/YdgH, Lonely Guy (LOG) family [Nucleotide transport and metabolism];


Pssm-ID: 441219  Cd Length: 184  Bit Score: 240.01  E-value: 3.10e-81
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79567911  10 RICVFCGSSSGNKTTYHDAALQLAHQLVERNIDLVYGGGSVGLMGLISQAVHDGGRHVLGIIPKSLAPREITGESIGEVI 89
Cdd:COG1611   1 SVCVFGGSRTGPDPPYYEAARELGRLLAERGFTLVTGGGPVGLMGAVADGALEAGGRSIGVIPHFLVEREVANPYLTELI 80
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79567911  90 TVSTMHQRKAEMGRQADAFIALPGGYGTFEELLEVITWSQLGIHTKPVGLLNVDGFYDSLLTFIDKAVDEGFVSSTARRI 169
Cdd:COG1611  81 VVDYMHERKAMMLELADAFVALPGGFGTLDELFEVLTLAQLGKHPKPIVLLNGNGFWDPLLDWLDHMLEEGFISPEDLDL 160
                       170       180
                ....*....|....*....|...
gi 79567911 170 IVSAPNAPQLLQLLEEYVPKHDD 192
Cdd:COG1611 161 LLVVDDPEEALDALEAYEPPYAS 183
Lysine_decarbox pfam03641
Possible lysine decarboxylase; The members of this family share a highly conserved motif ...
53-182 6.57e-63

Possible lysine decarboxylase; The members of this family share a highly conserved motif PGGXGTXXE that is probably functionally important. This family includes proteins annotated as lysine decarboxylases, although the evidence for this is not clear.


Pssm-ID: 397621  Cd Length: 130  Bit Score: 191.66  E-value: 6.57e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79567911    53 MGLISQAVHDGGRHVLGIIPKSLAPREITGESIGEVITVSTMHQRKAEMGRQADAFIALPGGYGTFEELLEVITWSQLGI 132
Cdd:pfam03641   1 MGAVADGALEAGGRVIGIIPKILLPEEIPNPIVTELIIVPDMHERKAAMAELADAFVALPGGFGTLEELFEILTWIQLGI 80
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 79567911   133 HTKPVGLLNVDGFYDSLLTFIDKAVDEGFVSSTARRIIVSAPNAPQLLQL 182
Cdd:pfam03641  81 HQKPIVLLNPDGYYDPLLEFIDHMVDEGFISPEARELIIVVDDPEELLEK 130
TIGR00730 TIGR00730
TIGR00730 family protein; This model represents one branch of a subfamily of proteins of ...
11-186 2.09e-60

TIGR00730 family protein; This model represents one branch of a subfamily of proteins of unknown function. Both PSI-BLAST and weak hits by this model show a low level of similarity to and suggest an evolutionary relationship of the subfamily to the DprA/Smf family of DNA-processing proteins involved in chromosomal transformation with foreign DNA. Both Aquifex aeolicus and Mycobacterium leprae have one member in each of two branches of this subfamily, suggesting that the branches may have distinct functions. [Hypothetical proteins, Conserved]


Pssm-ID: 129813 [Multi-domain]  Cd Length: 178  Bit Score: 186.95  E-value: 2.09e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79567911    11 ICVFCGSSSGNKTTYHDAALQLAHQLVERNIDLVYGGGSVGLMGLISQAVHDGGRHVLGIIPKSLAPREITGESIGEVIT 90
Cdd:TIGR00730   3 VCVYCGSSPGGNAAYKELAAELGAYLAGQGWGLVYGGGRVGLMGAIADAAMENGGTAVGVNPSGLFSGEVVHQNLTELIE 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79567911    91 VSTMHQRKAEMGRQADAFIALPGGYGTFEELLEVITWSQLGIHTKPVGLLNVDGFYDSLLTFIDKAVDEGFVSSTARRII 170
Cdd:TIGR00730  83 VNGMHERKAMMAELADAFIAMPGGFGTLEELFEVLTWAQLGIHQKPIILFNVNGHFDGLVEWLKYSIQEGFISESHLKLI 162
                         170
                  ....*....|....*.
gi 79567911   171 VSAPNAPQLLQLLEEY 186
Cdd:TIGR00730 163 HVVSRPDELIEQVQNY 178
 
Name Accession Description Interval E-value
PpnN COG1611
Nucleotide monophosphate nucleosidase PpnN/YdgH, Lonely Guy (LOG) family [Nucleotide transport ...
10-192 3.10e-81

Nucleotide monophosphate nucleosidase PpnN/YdgH, Lonely Guy (LOG) family [Nucleotide transport and metabolism];


Pssm-ID: 441219  Cd Length: 184  Bit Score: 240.01  E-value: 3.10e-81
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79567911  10 RICVFCGSSSGNKTTYHDAALQLAHQLVERNIDLVYGGGSVGLMGLISQAVHDGGRHVLGIIPKSLAPREITGESIGEVI 89
Cdd:COG1611   1 SVCVFGGSRTGPDPPYYEAARELGRLLAERGFTLVTGGGPVGLMGAVADGALEAGGRSIGVIPHFLVEREVANPYLTELI 80
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79567911  90 TVSTMHQRKAEMGRQADAFIALPGGYGTFEELLEVITWSQLGIHTKPVGLLNVDGFYDSLLTFIDKAVDEGFVSSTARRI 169
Cdd:COG1611  81 VVDYMHERKAMMLELADAFVALPGGFGTLDELFEVLTLAQLGKHPKPIVLLNGNGFWDPLLDWLDHMLEEGFISPEDLDL 160
                       170       180
                ....*....|....*....|...
gi 79567911 170 IVSAPNAPQLLQLLEEYVPKHDD 192
Cdd:COG1611 161 LLVVDDPEEALDALEAYEPPYAS 183
Lysine_decarbox pfam03641
Possible lysine decarboxylase; The members of this family share a highly conserved motif ...
53-182 6.57e-63

Possible lysine decarboxylase; The members of this family share a highly conserved motif PGGXGTXXE that is probably functionally important. This family includes proteins annotated as lysine decarboxylases, although the evidence for this is not clear.


Pssm-ID: 397621  Cd Length: 130  Bit Score: 191.66  E-value: 6.57e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79567911    53 MGLISQAVHDGGRHVLGIIPKSLAPREITGESIGEVITVSTMHQRKAEMGRQADAFIALPGGYGTFEELLEVITWSQLGI 132
Cdd:pfam03641   1 MGAVADGALEAGGRVIGIIPKILLPEEIPNPIVTELIIVPDMHERKAAMAELADAFVALPGGFGTLEELFEILTWIQLGI 80
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 79567911   133 HTKPVGLLNVDGFYDSLLTFIDKAVDEGFVSSTARRIIVSAPNAPQLLQL 182
Cdd:pfam03641  81 HQKPIVLLNPDGYYDPLLEFIDHMVDEGFISPEARELIIVVDDPEELLEK 130
TIGR00730 TIGR00730
TIGR00730 family protein; This model represents one branch of a subfamily of proteins of ...
11-186 2.09e-60

TIGR00730 family protein; This model represents one branch of a subfamily of proteins of unknown function. Both PSI-BLAST and weak hits by this model show a low level of similarity to and suggest an evolutionary relationship of the subfamily to the DprA/Smf family of DNA-processing proteins involved in chromosomal transformation with foreign DNA. Both Aquifex aeolicus and Mycobacterium leprae have one member in each of two branches of this subfamily, suggesting that the branches may have distinct functions. [Hypothetical proteins, Conserved]


Pssm-ID: 129813 [Multi-domain]  Cd Length: 178  Bit Score: 186.95  E-value: 2.09e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79567911    11 ICVFCGSSSGNKTTYHDAALQLAHQLVERNIDLVYGGGSVGLMGLISQAVHDGGRHVLGIIPKSLAPREITGESIGEVIT 90
Cdd:TIGR00730   3 VCVYCGSSPGGNAAYKELAAELGAYLAGQGWGLVYGGGRVGLMGAIADAAMENGGTAVGVNPSGLFSGEVVHQNLTELIE 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79567911    91 VSTMHQRKAEMGRQADAFIALPGGYGTFEELLEVITWSQLGIHTKPVGLLNVDGFYDSLLTFIDKAVDEGFVSSTARRII 170
Cdd:TIGR00730  83 VNGMHERKAMMAELADAFIAMPGGFGTLEELFEVLTWAQLGIHQKPIILFNVNGHFDGLVEWLKYSIQEGFISESHLKLI 162
                         170
                  ....*....|....*.
gi 79567911   171 VSAPNAPQLLQLLEEY 186
Cdd:TIGR00730 163 HVVSRPDELIEQVQNY 178
LDcluster4 pfam18306
SLOG cluster4 family; Family in the SLOG superfamily, observed as a standalone domain with ...
16-176 1.33e-10

SLOG cluster4 family; Family in the SLOG superfamily, observed as a standalone domain with little informative genome context, although related families in the SLOG superfamily are predicted to function in diverse conflict contexts.


Pssm-ID: 436397  Cd Length: 152  Bit Score: 57.59  E-value: 1.33e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79567911    16 GSSSGNKTTYHDAALQLAHQLVERNIDLVYGGGSvGLMGLISQAVHDGGRHVLGIIPkSLAPREITGESigEVITVSTM- 94
Cdd:pfam18306   8 GSGDIATPELLEIAYELGQLIAKRGWVLLTGGRP-GVMEAASRGAKEAGGLTVGILP-GLDDDEHSNAV--DIPIPTGMg 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 79567911    95 HQRKAEMGRQADAFIALPGGYGTFEELLevITWSQlgihTKPVGLLNvdgfydsllTFIDKAVDEGFVSSTARRIIVSAP 174
Cdd:pfam18306  84 LARNFINVLSSDVVIAIGGGSGTLSEIA--LALKE----GKPVILLG---------GWILSQLIFEKYKDTGKVIYAASP 148

                  ..
gi 79567911   175 NA 176
Cdd:pfam18306 149 EE 150
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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