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Conserved domains on  [gi|15225775|ref|NP_180861|]
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receptor like protein 24 [Arabidopsis thaliana]

Protein Classification

leucine-rich repeat domain-containing protein( domain architecture ID 1000136)

leucine-rich repeat (LRR) domain-containing protein may participate in protein-protein interactions

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PLN00113 super family cl33413
leucine-rich repeat receptor-like protein kinase; Provisional
 139-799 9.52e-65

leucine-rich repeat receptor-like protein kinase; Provisional


The actual alignment was detected with superfamily member PLN00113:

Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 234.74  E-value: 9.52e-65
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15225775  139 IDLSHNDLMGSF-PLVRNLGKLAVLDLSDNHFSGTLnPNNSLFELHSLRYLNLAFNNISSSLPSkfGNLNKLEVLSLSFN 217
Cdd:PLN00113  74 IDLSGKNISGKIsSAIFRLPYIQTINLSNNQLSGPI-PDDIFTTSSSLRYLNLSNNNFTGSIPR--GSIPNLETLDLSNN 150

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15225775  218 GFSGQCFPTISNLTRITQLYLHNNELTGSFPL-VQNLTKLSFLGLSDNLFSGTIPSYLFTFPSLstldlrendlsgsiev 296
Cdd:PLN00113 151 MLSGEIPNDIGSFSSLKVLDLGGNVLVGKIPNsLTNLTSLEFLTLASNQLVGQIPRELGQMKSL---------------- 214

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15225775  297 pnsstssklEIMYLGFNHLEGKILEPISKLINLKRLDLSFLNTSYPIDLNLlSPLKSLSYLDFSGNslspaslssssyip 376
Cdd:PLN00113 215 ---------KWIYLGYNNLSGEIPYEIGGLTSLNHLDLVYNNLTGPIPSSL-GNLKNLQYLFLYQN-------------- 270

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15225775  377 lsmesivlSLCGirEFPNILKHLQNLIHIDITSNQIKGKIPEWLWTLPQLsfvdisnnsfngfqgsaevfvnlsvRILML 456
Cdd:PLN00113 271 --------KLSG--PIPPSIFSLQKLISLDLSDNSLSGEIPELVIQLQNL-------------------------EILHL 315

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15225775  457 DANNFEGALP----TLP-LSIIGFSAihNSFTGEIPLSICNRTSLTMVDLSYNNFTGPIPQ--CLSNFMF-VNLRKNDLE 528
Cdd:PLN00113 316 FSNNFTGKIPvaltSLPrLQVLQLWS--NKFSGEIPKNLGKHNNLTVLDLSTNNLTGEIPEglCSSGNLFkLILFSNSLE 393

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15225775  529 GSIPDTFYTDSSLKSLDVGYNRLTGKLPRSLLNCSSLRFLSVDNNRVKDTFPFWLKALPNLRVLTLRSNKFYGPISpphq 608
Cdd:PLN00113 394 GEIPKSLGACRSLRRVRLQDNSFSGELPSEFTKLPLVYFLDISNNNLQGRINSRKWDMPSLQMLSLARNKFFGGLP---- 469

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15225775  609 GPLGFPELRIFEIADNMFTGSLPPSFfvnwkasaltknedgglymvyeydkaanspvrytytdtidlqykglhmeqeRVL 688
Cdd:PLN00113 470 DSFGSKRLENLDLSRNQFSGAVPRKL---------------------------------------------------GSL 498

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15225775  689 TSYAAIDFSGNRLQGQIPESIGLLKALIALNLSNNAFTGHIPLSFANLMNLESLDMSGNQLSGTIPNGLGSLSFLVYISV 768
Cdd:PLN00113 499 SELMQLKLSENKLSGEIPDELSSCKKLVSLDLSHNQLSGQIPASFSEMPVLSQLDLSQNQLSGEIPKNLGNVESLVQVNI 578

                        650       660       670
                 ....*....|....*....|....*....|.
gi 15225775  769 AHNKLKGEIPQGTQITGQIKSSFEGNAGLCG 799
Cdd:PLN00113 579 SHNHLHGSLPSTGAFLAINASAVAGNIDLCG 609
 
Name Accession Description Interval E-value
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 139-799 9.52e-65

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 234.74  E-value: 9.52e-65
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15225775  139 IDLSHNDLMGSF-PLVRNLGKLAVLDLSDNHFSGTLnPNNSLFELHSLRYLNLAFNNISSSLPSkfGNLNKLEVLSLSFN 217
Cdd:PLN00113  74 IDLSGKNISGKIsSAIFRLPYIQTINLSNNQLSGPI-PDDIFTTSSSLRYLNLSNNNFTGSIPR--GSIPNLETLDLSNN 150

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15225775  218 GFSGQCFPTISNLTRITQLYLHNNELTGSFPL-VQNLTKLSFLGLSDNLFSGTIPSYLFTFPSLstldlrendlsgsiev 296
Cdd:PLN00113 151 MLSGEIPNDIGSFSSLKVLDLGGNVLVGKIPNsLTNLTSLEFLTLASNQLVGQIPRELGQMKSL---------------- 214

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15225775  297 pnsstssklEIMYLGFNHLEGKILEPISKLINLKRLDLSFLNTSYPIDLNLlSPLKSLSYLDFSGNslspaslssssyip 376
Cdd:PLN00113 215 ---------KWIYLGYNNLSGEIPYEIGGLTSLNHLDLVYNNLTGPIPSSL-GNLKNLQYLFLYQN-------------- 270

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15225775  377 lsmesivlSLCGirEFPNILKHLQNLIHIDITSNQIKGKIPEWLWTLPQLsfvdisnnsfngfqgsaevfvnlsvRILML 456
Cdd:PLN00113 271 --------KLSG--PIPPSIFSLQKLISLDLSDNSLSGEIPELVIQLQNL-------------------------EILHL 315

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15225775  457 DANNFEGALP----TLP-LSIIGFSAihNSFTGEIPLSICNRTSLTMVDLSYNNFTGPIPQ--CLSNFMF-VNLRKNDLE 528
Cdd:PLN00113 316 FSNNFTGKIPvaltSLPrLQVLQLWS--NKFSGEIPKNLGKHNNLTVLDLSTNNLTGEIPEglCSSGNLFkLILFSNSLE 393

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15225775  529 GSIPDTFYTDSSLKSLDVGYNRLTGKLPRSLLNCSSLRFLSVDNNRVKDTFPFWLKALPNLRVLTLRSNKFYGPISpphq 608
Cdd:PLN00113 394 GEIPKSLGACRSLRRVRLQDNSFSGELPSEFTKLPLVYFLDISNNNLQGRINSRKWDMPSLQMLSLARNKFFGGLP---- 469

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15225775  609 GPLGFPELRIFEIADNMFTGSLPPSFfvnwkasaltknedgglymvyeydkaanspvrytytdtidlqykglhmeqeRVL 688
Cdd:PLN00113 470 DSFGSKRLENLDLSRNQFSGAVPRKL---------------------------------------------------GSL 498

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15225775  689 TSYAAIDFSGNRLQGQIPESIGLLKALIALNLSNNAFTGHIPLSFANLMNLESLDMSGNQLSGTIPNGLGSLSFLVYISV 768
Cdd:PLN00113 499 SELMQLKLSENKLSGEIPDELSSCKKLVSLDLSHNQLSGQIPASFSEMPVLSQLDLSQNQLSGEIPKNLGNVESLVQVNI 578

                        650       660       670
                 ....*....|....*....|....*....|.
gi 15225775  769 AHNKLKGEIPQGTQITGQIKSSFEGNAGLCG 799
Cdd:PLN00113 579 SHNHLHGSLPSTGAFLAINASAVAGNIDLCG 609
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
90-479 4.28e-21

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 96.93  E-value: 4.28e-21
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15225775  90 TLKSNSSLFGFHQLRYLALNRNNFTSASLPSEFCNLNKLKLLSLFSNGFIDLSHNDLMGSFPLVRNLGKLAVLDLSDNHF 169
Cdd:COG4886  20 LLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLT 99

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15225775 170 SGTLNPNNSLFELHSLRYLNLAFNNIsSSLPSKFGNLNKLEVLSLSFNGFSgQCFPTISNLTRITQLYLHNNELTGSFPL 249
Cdd:COG4886 100 ELDLSGNEELSNLTNLESLDLSGNQL-TDLPEELANLTNLKELDLSNNQLT-DLPEPLGNLTNLKSLDLSNNQLTDLPEE 177

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15225775 250 VQNLTKLSFLGLSDNLFSgTIPSYLFTFPSLSTLDLRENDLSgsiEVPNS-STSSKLEIMYLGFNHLEGkiLEPISKLIN 328
Cdd:COG4886 178 LGNLTNLKELDLSNNQIT-DLPEPLGNLTNLEELDLSGNQLT---DLPEPlANLTNLETLDLSNNQLTD--LPELGNLTN 251

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15225775 329 LKRLDLSFLNTSypiDLNLLSPLKSLSYLDFSGNSLSPASLSSSsyIPLSMESIVLSLCGIREFPNILKHLQNLIHIDIT 408
Cdd:COG4886 252 LEELDLSNNQLT---DLPPLANLTNLKTLDLSNNQLTDLKLKEL--ELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLL 326

                       330       340       350       360       370       380       390
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 15225775 409 SNQIKGKIPEWLWTLPQLSFVDISNNSFNGFQGSAEVFVNLSVRILMLDANNFEGALPTLPLSIIGFSAIH 479
Cdd:COG4886 327 LLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLALLLLTLLLLLLTTT 397
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 230-434 6.41e-07

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 50.94  E-value: 6.41e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15225775 230 LTRITQLYLHNNELTgSFPLVQNLTKLSFLGLSDNLFSgTIPSyLFTFPSLSTLDLRENDLSgSIEvpNSSTSSKLEIMY 309
Cdd:cd21340   1 LKRITHLYLNDKNIT-KIDNLSLCKNLKVLYLYDNKIT-KIEN-LEFLTNLTHLYLQNNQIE-KIE--NLENLVNLKKLY 74

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15225775 310 LGFN---HLEGkiLEpisKLINLKRLDLS----FLNTSYPIDLNLLSPL-KSLSYLDFSGNslspaslssssyiplSMES 381
Cdd:cd21340  75 LGGNrisVVEG--LE---NLTNLEELHIEnqrlPPGEKLTFDPRSLAALsNSLRVLNISGN---------------NIDS 134

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|....*
gi 15225775 382 IvlslcgirefpNILKHLQNLIHIDITSNQIK--GKIPEWLWTLPQLSFVDISNN 434
Cdd:cd21340 135 L-----------EPLAPLRNLEQLDASNNQISdlEELLDLLSSWPSLRELDLTGN 178
LRR_8 pfam13855
Leucine rich repeat;
184-243 4.73e-05

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 41.74  E-value: 4.73e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 15225775   184 SLRYLNLAFNNISSSLPSKFGNLNKLEVLSLSFN---GFSGQCFptiSNLTRITQLYLHNNEL 243
Cdd:pfam13855   2 NLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNlltTLSPGAF---SGLPSLRYLDLSGNRL 61
 
Name Accession Description Interval E-value
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 139-799 9.52e-65

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 234.74  E-value: 9.52e-65
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15225775  139 IDLSHNDLMGSF-PLVRNLGKLAVLDLSDNHFSGTLnPNNSLFELHSLRYLNLAFNNISSSLPSkfGNLNKLEVLSLSFN 217
Cdd:PLN00113  74 IDLSGKNISGKIsSAIFRLPYIQTINLSNNQLSGPI-PDDIFTTSSSLRYLNLSNNNFTGSIPR--GSIPNLETLDLSNN 150

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15225775  218 GFSGQCFPTISNLTRITQLYLHNNELTGSFPL-VQNLTKLSFLGLSDNLFSGTIPSYLFTFPSLstldlrendlsgsiev 296
Cdd:PLN00113 151 MLSGEIPNDIGSFSSLKVLDLGGNVLVGKIPNsLTNLTSLEFLTLASNQLVGQIPRELGQMKSL---------------- 214

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15225775  297 pnsstssklEIMYLGFNHLEGKILEPISKLINLKRLDLSFLNTSYPIDLNLlSPLKSLSYLDFSGNslspaslssssyip 376
Cdd:PLN00113 215 ---------KWIYLGYNNLSGEIPYEIGGLTSLNHLDLVYNNLTGPIPSSL-GNLKNLQYLFLYQN-------------- 270

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15225775  377 lsmesivlSLCGirEFPNILKHLQNLIHIDITSNQIKGKIPEWLWTLPQLsfvdisnnsfngfqgsaevfvnlsvRILML 456
Cdd:PLN00113 271 --------KLSG--PIPPSIFSLQKLISLDLSDNSLSGEIPELVIQLQNL-------------------------EILHL 315

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15225775  457 DANNFEGALP----TLP-LSIIGFSAihNSFTGEIPLSICNRTSLTMVDLSYNNFTGPIPQ--CLSNFMF-VNLRKNDLE 528
Cdd:PLN00113 316 FSNNFTGKIPvaltSLPrLQVLQLWS--NKFSGEIPKNLGKHNNLTVLDLSTNNLTGEIPEglCSSGNLFkLILFSNSLE 393

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15225775  529 GSIPDTFYTDSSLKSLDVGYNRLTGKLPRSLLNCSSLRFLSVDNNRVKDTFPFWLKALPNLRVLTLRSNKFYGPISpphq 608
Cdd:PLN00113 394 GEIPKSLGACRSLRRVRLQDNSFSGELPSEFTKLPLVYFLDISNNNLQGRINSRKWDMPSLQMLSLARNKFFGGLP---- 469

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15225775  609 GPLGFPELRIFEIADNMFTGSLPPSFfvnwkasaltknedgglymvyeydkaanspvrytytdtidlqykglhmeqeRVL 688
Cdd:PLN00113 470 DSFGSKRLENLDLSRNQFSGAVPRKL---------------------------------------------------GSL 498

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15225775  689 TSYAAIDFSGNRLQGQIPESIGLLKALIALNLSNNAFTGHIPLSFANLMNLESLDMSGNQLSGTIPNGLGSLSFLVYISV 768
Cdd:PLN00113 499 SELMQLKLSENKLSGEIPDELSSCKKLVSLDLSHNQLSGQIPASFSEMPVLSQLDLSQNQLSGEIPKNLGNVESLVQVNI 578

                        650       660       670
                 ....*....|....*....|....*....|.
gi 15225775  769 AHNKLKGEIPQGTQITGQIKSSFEGNAGLCG 799
Cdd:PLN00113 579 SHNHLHGSLPSTGAFLAINASAVAGNIDLCG 609
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 432-813 6.50e-31

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 130.74  E-value: 6.50e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15225775  432 SNNSFNGFQGsaeVFVNLSVRILMLD--ANNFEGALPT----LP-LSIIGFSAihNSFTGEIPLSI-CNRTSLTMVDLSY 503
Cdd:PLN00113  53 SSADVCLWQG---ITCNNSSRVVSIDlsGKNISGKISSaifrLPyIQTINLSN--NQLSGPIPDDIfTTSSSLRYLNLSN 127

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15225775  504 NNFTGPIPQ-CLSNFMFVNLRKNDLEGSIPDTFYTDSSLKSLDVGYNRLTGKLPRSLLNCSSLRFLSVDNNRVKDTFPFW 582
Cdd:PLN00113 128 NNFTGSIPRgSIPNLETLDLSNNMLSGEIPNDIGSFSSLKVLDLGGNVLVGKIPNSLTNLTSLEFLTLASNQLVGQIPRE 207

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15225775  583 LKALPNLRVLTLRSNKFYGPIsPPHQGplGFPELRIFEIADNMFTGSLPPSFfvnwkasaltknedgglymvyeydkaan 662
Cdd:PLN00113 208 LGQMKSLKWIYLGYNNLSGEI-PYEIG--GLTSLNHLDLVYNNLTGPIPSSL---------------------------- 256

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15225775  663 spvrytyTDTIDLQYKGLHMeqervltsyaaidfsgNRLQGQIPESIGLLKALIALNLSNNAFTGHIPLSFANLMNLESL 742
Cdd:PLN00113 257 -------GNLKNLQYLFLYQ----------------NKLSGPIPPSIFSLQKLISLDLSDNSLSGEIPELVIQLQNLEIL 313

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15225775  743 DMSGNQLSGTIPNGLGSLSFLVYISVAHNKLKGEIPQ--GTQ------------ITGQIKSSFEGNAGLCGLPLQETCFD 808
Cdd:PLN00113 314 HLFSNNFTGKIPVALTSLPRLQVLQLWSNKFSGEIPKnlGKHnnltvldlstnnLTGEIPEGLCSSGNLFKLILFSNSLE 393


                 ....*
gi 15225775  809 SSVPP 813
Cdd:PLN00113 394 GEIPK 398
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 95-438 3.46e-25

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 112.63  E-value: 3.46e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15225775   95 SSLFGFHQLRYLALNRNNFTSASLPSEFCNLNKLKllslfsngfIDLSHNDLMGSFP-LVRNLGKLAVLDLSDNHFSGTL 173
Cdd:PLN00113 254 SSLGNLKNLQYLFLYQNKLSGPIPPSIFSLQKLIS---------LDLSDNSLSGEIPeLVIQLQNLEILHLFSNNFTGKI 324

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15225775  174 npNNSLFELHSLRYLNLAFNNISSSLPSKFGNLNKLEVLSLSFNGFSGQCFPTISNLTRITQLYLHNNELTGSFP----- 248
Cdd:PLN00113 325 --PVALTSLPRLQVLQLWSNKFSGEIPKNLGKHNNLTVLDLSTNNLTGEIPEGLCSSGNLFKLILFSNSLEGEIPkslga 402

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15225775  249 -----------------LVQNLTKLS---FLGLSDNLFSGTIPSYLFTFPSLSTLDLRENDLSGsiEVPNSSTSSKLEIM 308
Cdd:PLN00113 403 crslrrvrlqdnsfsgeLPSEFTKLPlvyFLDISNNNLQGRINSRKWDMPSLQMLSLARNKFFG--GLPDSFGSKRLENL 480

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15225775  309 YLGFNHLEGKILEPISKLINLKRLDLSFLNTSYPIDlNLLSPLKSLSYLDFSGNslspaslSSSSYIPLSMEsivlslcg 388
Cdd:PLN00113 481 DLSRNQFSGAVPRKLGSLSELMQLKLSENKLSGEIP-DELSSCKKLVSLDLSHN-------QLSGQIPASFS-------- 544

                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|
gi 15225775  389 irEFPnILKHLqnlihiDITSNQIKGKIPEWLWTLPQLSFVDISNNSFNG 438
Cdd:PLN00113 545 --EMP-VLSQL------DLSQNQLSGEIPKNLGNVESLVQVNISHNHLHG 585
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
90-479 4.28e-21

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 96.93  E-value: 4.28e-21
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15225775  90 TLKSNSSLFGFHQLRYLALNRNNFTSASLPSEFCNLNKLKLLSLFSNGFIDLSHNDLMGSFPLVRNLGKLAVLDLSDNHF 169
Cdd:COG4886  20 LLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLT 99

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15225775 170 SGTLNPNNSLFELHSLRYLNLAFNNIsSSLPSKFGNLNKLEVLSLSFNGFSgQCFPTISNLTRITQLYLHNNELTGSFPL 249
Cdd:COG4886 100 ELDLSGNEELSNLTNLESLDLSGNQL-TDLPEELANLTNLKELDLSNNQLT-DLPEPLGNLTNLKSLDLSNNQLTDLPEE 177

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15225775 250 VQNLTKLSFLGLSDNLFSgTIPSYLFTFPSLSTLDLRENDLSgsiEVPNS-STSSKLEIMYLGFNHLEGkiLEPISKLIN 328
Cdd:COG4886 178 LGNLTNLKELDLSNNQIT-DLPEPLGNLTNLEELDLSGNQLT---DLPEPlANLTNLETLDLSNNQLTD--LPELGNLTN 251

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15225775 329 LKRLDLSFLNTSypiDLNLLSPLKSLSYLDFSGNSLSPASLSSSsyIPLSMESIVLSLCGIREFPNILKHLQNLIHIDIT 408
Cdd:COG4886 252 LEELDLSNNQLT---DLPPLANLTNLKTLDLSNNQLTDLKLKEL--ELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLL 326

                       330       340       350       360       370       380       390
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 15225775 409 SNQIKGKIPEWLWTLPQLSFVDISNNSFNGFQGSAEVFVNLSVRILMLDANNFEGALPTLPLSIIGFSAIH 479
Cdd:COG4886 327 LLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLALLLLTLLLLLLTTT 397
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
139-439 2.29e-20

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 94.62  E-value: 2.29e-20
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15225775 139 IDLSHNDLMGSFPLVRNLGKLAVLDLSDNHFSgTLNPnnSLFELHSLRYLNLAFNNISSsLPSKFGNLNKLEVLSLSFNG 218
Cdd:COG4886 118 LDLSGNQLTDLPEELANLTNLKELDLSNNQLT-DLPE--PLGNLTNLKSLDLSNNQLTD-LPEELGNLTNLKELDLSNNQ 193

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15225775 219 FSGqcFP-TISNLTRITQLYLHNNELTgSFPL-VQNLTKLSFLGLSDNLFSgTIPSyLFTFPSLSTLDLRENDLSgsiEV 296
Cdd:COG4886 194 ITD--LPePLGNLTNLEELDLSGNQLT-DLPEpLANLTNLETLDLSNNQLT-DLPE-LGNLTNLEELDLSNNQLT---DL 265

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15225775 297 PNSSTSSKLEIMYLGFNHLEGKILEPISKLINLKRLDLSFLNTSYPIDLNLLSPLKSLSYLDFSGNSLSPASLSSSSYIP 376
Cdd:COG4886 266 PPLANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLS 345

                       250       260       270       280       290       300
                ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 15225775 377 LSMESIVLSLCGIREFPNILKHLQNLIHIDITSNQIKGKIPEWLWTLPQLSFVDISNNSFNGF 439
Cdd:COG4886 346 LLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLALLLLTLLLLLLTTTAGVLLLTLALL 408
PLN03150 PLN03150
hypothetical protein; Provisional
 701-806 1.26e-18

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 90.65  E-value: 1.26e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15225775  701 LQGQIPESIGLLKALIALNLSNNAFTGHIPLSFANLMNLESLDMSGNQLSGTIPNGLGSLSFLVYISVAHNKLKGEIPQ- 779
Cdd:PLN03150 430 LRGFIPNDISKLRHLQSINLSGNSIRGNIPPSLGSITSLEVLDLSYNSFNGSIPESLGQLTSLRILNLNGNSLSGRVPAa 509

                         90       100
                 ....*....|....*....|....*...
gi 15225775  780 -GTQITGQIKSSFEGNAGLCGLPLQETC 806
Cdd:PLN03150 510 lGGRLLHRASFNFTDNAGLCGIPGLRAC 537
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
134-541 1.08e-17

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 86.53  E-value: 1.08e-17
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15225775 134 FSNGFIDLSHNDLMGSFPLVRNLGKLAVLDLSDNHFSGTLNPNNSLFELHSLRYLNLAFNNISSSLPSKFGNLNKLEVLS 213
Cdd:COG4886  23 TLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELD 102

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15225775 214 LSFNgfsgqcfPTISNLTRITQLYLHNNELTGSFPLVQNLTKLSFLGLSDNLFSgTIPSYLFTFPSLSTLDLRENDLSgs 293
Cdd:COG4886 103 LSGN-------EELSNLTNLESLDLSGNQLTDLPEELANLTNLKELDLSNNQLT-DLPEPLGNLTNLKSLDLSNNQLT-- 172

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15225775 294 iEVPNS-STSSKLEIMYLGFNHLEgKILEPISKLINLKRLDLSFLN-TSYPIDlnlLSPLKSLSYLDFSGNslspaslss 371
Cdd:COG4886 173 -DLPEElGNLTNLKELDLSNNQIT-DLPEPLGNLTNLEELDLSGNQlTDLPEP---LANLTNLETLDLSNN--------- 238

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15225775 372 ssyiplsmesivlslcGIREFPNiLKHLQNLIHIDITSNQIKGkIPEwLWTLPQLSFVDISNNSFNGFQGSAEVFVNLSV 451
Cdd:COG4886 239 ----------------QLTDLPE-LGNLTNLEELDLSNNQLTD-LPP-LANLTNLKTLDLSNNQLTDLKLKELELLLGLN 299

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15225775 452 RILMLDANNFEGALPTLPLSIIGFSAIHNSFTGEIPLSICNRTSLTMVDLSYNNFTGPIPQCLSNFMFVNLRKNDLEGSI 531
Cdd:COG4886 300 SLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATL 379

                       410
                ....*....|
gi 15225775 532 PDTFYTDSSL 541
Cdd:COG4886 380 LTLALLLLTL 389
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
229-599 6.57e-15

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 77.67  E-value: 6.57e-15
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15225775 229 NLTRITQLYLHNNELTGSFPLVQNLTKLSFLGLSDNLFSGTIPSYLFTFPSLSTLDLRENDLSGSIEVPNSSTSSKLEIM 308
Cdd:COG4886   1 LLLLLLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLL 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15225775 309 YLGfnhLEGKILEPISKLINLKRLDLSflntsypiDLNLLSPLKSLSYLDFSGNslspaslssssyiplsmesivlslcG 388
Cdd:COG4886  81 LLS---LLLLGLTDLGDLTNLTELDLS--------GNEELSNLTNLESLDLSGN-------------------------Q 124

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15225775 389 IREFPNILKHLQNLIHIDITSNQIKgKIPEWLWTLPQLSFVDISNNSFNGFQGSAEVFVNLsvRILMLDANNFEgalptl 468
Cdd:COG4886 125 LTDLPEELANLTNLKELDLSNNQLT-DLPEPLGNLTNLKSLDLSNNQLTDLPEELGNLTNL--KELDLSNNQIT------ 195

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15225775 469 plsiigfsaihnsftgEIPLSICNRTSLTMVDLSYNNFTgpipqclsnfmfvnlrkndlegSIPDTFYTDSSLKSLDVGY 548
Cdd:COG4886 196 ----------------DLPEPLGNLTNLEELDLSGNQLT----------------------DLPEPLANLTNLETLDLSN 237

                       330       340       350       360       370
                ....*....|....*....|....*....|....*....|....*....|.
gi 15225775 549 NRLTgKLPrSLLNCSSLRFLSVDNNRVKDTFPfwLKALPNLRVLTLRSNKF 599
Cdd:COG4886 238 NQLT-DLP-ELGNLTNLEELDLSNNQLTDLPP--LANLTNLKTLDLSNNQL 284
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
457-789 1.61e-10

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 64.18  E-value: 1.61e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15225775 457 DANNFEGALPTLPLSIIGFSAIHNSFTGEIPLSICNRTSLTMVDLSYNNFTGPipqcLSNFMFVNLRKNDLEgSIPDTFY 536
Cdd:COG4886  59 DLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGNEELSN----LTNLESLDLSGNQLT-DLPEELA 133

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15225775 537 TDSSLKSLDVGYNRLTgKLPRSLLNCSSLRFLSVDNNRVKDtFPFWLKALPNLRVLTLRSNKFY---GPISpphqgplGF 613
Cdd:COG4886 134 NLTNLKELDLSNNQLT-DLPEPLGNLTNLKSLDLSNNQLTD-LPEELGNLTNLKELDLSNNQITdlpEPLG-------NL 204

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15225775 614 PELRIFEIADNMFTgSLPPSFfvnwkaSALTKnedgglymvyeydkaanspvrytytdtidLQYkglhmeqervltsyaa 693
Cdd:COG4886 205 TNLEELDLSGNQLT-DLPEPL------ANLTN-----------------------------LET---------------- 232

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15225775 694 IDFSGNRLQgQIPEsIGLLKALIALNLSNNAFTgHIPLSfANLMNLESLDMSGNQLSGTIPNGLGSLSFLVYISVAHNKL 773
Cdd:COG4886 233 LDLSNNQLT-DLPE-LGNLTNLEELDLSNNQLT-DLPPL-ANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLL 308

                       330
                ....*....|....*.
gi 15225775 774 KGEIPQGTQITGQIKS 789
Cdd:COG4886 309 NLLELLILLLLLTTLL 324
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
427-784 2.29e-10

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 63.80  E-value: 2.29e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15225775 427 SFVDISNNSFNGFQGSAEVFVNLSVRILMLDANNFEGALPTLPLSIIGFSAIHNSFTGEIPLSICNRTSLTMVDLSYNNF 506
Cdd:COG4886   8 LTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLL 87

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15225775 507 TGPIPQCLSNFMFVNLRKNDLEGSIpdtfytdSSLKSLDVGYNRLTgKLPRSLLNCSSLRFLSVDNNRVKDtFPFWLKAL 586
Cdd:COG4886  88 GLTDLGDLTNLTELDLSGNEELSNL-------TNLESLDLSGNQLT-DLPEELANLTNLKELDLSNNQLTD-LPEPLGNL 158

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15225775 587 PNLRVLTLRSNKFygpispphqgplgfpelrifeiadnmftGSLPPSFfvnwkaSALTKnedgglymvyeydkaanspvr 666
Cdd:COG4886 159 TNLKSLDLSNNQL----------------------------TDLPEEL------GNLTN--------------------- 183

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15225775 667 ytytdtidLQYkglhmeqervltsyaaIDFSGNRLQgQIPESIGLLKALIALNLSNNAFTgHIPLSFANLMNLESLDMSG 746
Cdd:COG4886 184 --------LKE----------------LDLSNNQIT-DLPEPLGNLTNLEELDLSGNQLT-DLPEPLANLTNLETLDLSN 237

                       330       340       350
                ....*....|....*....|....*....|....*...
gi 15225775 747 NQLSgTIPNgLGSLSFLVYISVAHNKLKgEIPQGTQIT 784
Cdd:COG4886 238 NQLT-DLPE-LGNLTNLEELDLSNNQLT-DLPPLANLT 272
PLN03150 PLN03150
hypothetical protein; Provisional
 499-587 2.92e-08

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 57.52  E-value: 2.92e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15225775  499 VDLSYNNFTGPIPQCLSNFMF---VNLRKNDLEGSIPDTFYTDSSLKSLDVGYNRLTGKLPRSLLNCSSLRFLSVDNNRV 575
Cdd:PLN03150 423 LGLDNQGLRGFIPNDISKLRHlqsINLSGNSIRGNIPPSLGSITSLEVLDLSYNSFNGSIPESLGQLTSLRILNLNGNSL 502

                         90
                 ....*....|..
gi 15225775  576 KDTFPFWLKALP 587
Cdd:PLN03150 503 SGRVPAALGGRL 514
PLN03150 PLN03150
hypothetical protein; Provisional
 177-248 5.66e-08

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 56.36  E-value: 5.66e-08
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 15225775  177 NSLFELHSLRYLNLAFNNISSSLPSKFGNLNKLEVLSLSFNGFSGQCFPTISNLTRITQLYLHNNELTGSFP 248
Cdd:PLN03150 436 NDISKLRHLQSINLSGNSIRGNIPPSLGSITSLEVLDLSYNSFNGSIPESLGQLTSLRILNLNGNSLSGRVP 507
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 230-434 6.41e-07

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 50.94  E-value: 6.41e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15225775 230 LTRITQLYLHNNELTgSFPLVQNLTKLSFLGLSDNLFSgTIPSyLFTFPSLSTLDLRENDLSgSIEvpNSSTSSKLEIMY 309
Cdd:cd21340   1 LKRITHLYLNDKNIT-KIDNLSLCKNLKVLYLYDNKIT-KIEN-LEFLTNLTHLYLQNNQIE-KIE--NLENLVNLKKLY 74

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15225775 310 LGFN---HLEGkiLEpisKLINLKRLDLS----FLNTSYPIDLNLLSPL-KSLSYLDFSGNslspaslssssyiplSMES 381
Cdd:cd21340  75 LGGNrisVVEG--LE---NLTNLEELHIEnqrlPPGEKLTFDPRSLAALsNSLRVLNISGN---------------NIDS 134

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|....*
gi 15225775 382 IvlslcgirefpNILKHLQNLIHIDITSNQIK--GKIPEWLWTLPQLSFVDISNN 434
Cdd:cd21340 135 L-----------EPLAPLRNLEQLDASNNQISdlEELLDLLSSWPSLRELDLTGN 178
PLN03150 PLN03150
hypothetical protein; Provisional
 480-532 8.95e-07

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 52.51  E-value: 8.95e-07
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 15225775  480 NSFTGEIPLSICNRTSLTMVDLSYNNFTGPIPQC---LSNFMFVNLRKNDLEGSIP 532
Cdd:PLN03150 452 NSIRGNIPPSLGSITSLEVLDLSYNSFNGSIPESlgqLTSLRILNLNGNSLSGRVP 507
LRR_RI cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ...
 184-362 4.21e-06

Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).


Pssm-ID: 238064 [Multi-domain]  Cd Length: 319  Bit Score: 49.66  E-value: 4.21e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15225775 184 SLRYLNLAFNNISS------SLPSKFGNLNKLEVLSLSFNGFSGQCFPTISNLTRITQL---YLHNNELTGS-FPLVQ-- 251
Cdd:cd00116  52 SLKELCLSLNETGRiprglqSLLQGLTKGCGLQELDLSDNALGPDGCGVLESLLRSSSLqelKLNNNGLGDRgLRLLAkg 131

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15225775 252 ---NLTKLSFLGLSDNLFSGT----IPSYLFTFPSLSTLDLRENDLSGS-IEV--PNSSTSSKLEIMYL---GFNHLEGK 318
Cdd:cd00116 132 lkdLPPALEKLVLGRNRLEGAsceaLAKALRANRDLKELNLANNGIGDAgIRAlaEGLKANCNLEVLDLnnnGLTDEGAS 211

                       170       180       190       200
                ....*....|....*....|....*....|....*....|....*....
gi 15225775 319 IL-EPISKLINLKRLDLSFLNTS----YPIDLNLLSPLKSLSYLDFSGN 362
Cdd:cd00116 212 ALaETLASLKSLEVLNLGDNNLTdagaAALASALLSPNISLLTLSLSCN 260
PLN03150 PLN03150
hypothetical protein; Provisional
 388-466 4.60e-06

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 50.20  E-value: 4.60e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15225775  388 GIREF-PNILKHLQNLIHIDITSNQIKGKIPEWLWTLPQLSFVDISNNSFNGfqGSAEVFVNL-SVRILMLDANNFEGAL 465
Cdd:PLN03150 429 GLRGFiPNDISKLRHLQSINLSGNSIRGNIPPSLGSITSLEVLDLSYNSFNG--SIPESLGQLtSLRILNLNGNSLSGRV 506


                 .
gi 15225775  466 P 466
Cdd:PLN03150 507 P 507
PLN03150 PLN03150
hypothetical protein; Provisional
 188-274 1.13e-05

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 49.04  E-value: 1.13e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15225775  188 LNLAFNNISSSLPSKFGNLNKLEVLSLSFNGFSGQCFPTISNLTRITQLYLHNNELTGSFP-LVQNLTKLSFLGLSDNLF 266
Cdd:PLN03150 423 LGLDNQGLRGFIPNDISKLRHLQSINLSGNSIRGNIPPSLGSITSLEVLDLSYNSFNGSIPeSLGQLTSLRILNLNGNSL 502


                 ....*...
gi 15225775  267 SGTIPSYL 274
Cdd:PLN03150 503 SGRVPAAL 510
PLN03150 PLN03150
hypothetical protein; Provisional
 233-319 1.32e-05

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 48.66  E-value: 1.32e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15225775  233 ITQLYLHNNELTGSFP-LVQNLTKLSFLGLSDNLFSGTIPSYLFTFPSLSTLDLRENDLSGSIevPNS-STSSKLEIMYL 310
Cdd:PLN03150 420 IDGLGLDNQGLRGFIPnDISKLRHLQSINLSGNSIRGNIPPSLGSITSLEVLDLSYNSFNGSI--PESlGQLTSLRILNL 497


                 ....*....
gi 15225775  311 GFNHLEGKI 319
Cdd:PLN03150 498 NGNSLSGRV 506
PLN03150 PLN03150
hypothetical protein; Provisional
 139-223 1.54e-05

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 48.66  E-value: 1.54e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15225775  139 IDLSHNDLMGSFPL-VRNLGKLAVLDLSDNHFSGTLNpnNSLFELHSLRYLNLAFNNISSSLPSKFGNLnKLEVLSLSFN 217
Cdd:PLN03150 447 INLSGNSIRGNIPPsLGSITSLEVLDLSYNSFNGSIP--ESLGQLTSLRILNLNGNSLSGRVPAALGGR-LLHRASFNFT 523


                 ....*.
gi 15225775  218 GFSGQC 223
Cdd:PLN03150 524 DNAGLC 529
LRR_8 pfam13855
Leucine rich repeat;
184-243 4.73e-05

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 41.74  E-value: 4.73e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 15225775   184 SLRYLNLAFNNISSSLPSKFGNLNKLEVLSLSFN---GFSGQCFptiSNLTRITQLYLHNNEL 243
Cdd:pfam13855   2 NLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNlltTLSPGAF---SGLPSLRYLDLSGNRL 61
LRR_8 pfam13855
Leucine rich repeat;
520-575 1.35e-04

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 40.59  E-value: 1.35e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 15225775   520 VNLRKNDLEGSIPDTFYTDSSLKSLDVGYNRLTGKLPRSLLNCSSLRFLSVDNNRV 575
Cdd:pfam13855   6 LDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
PLN03150 PLN03150
hypothetical protein; Provisional
 520-624 2.20e-04

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 44.81  E-value: 2.20e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15225775  520 VNLRKNDLEGSIPDTFYTDSSLKSLDVGYNRLTGKLPRSLLNCSSLRFLSVDNNRVKDTFPFWLKALPNLRVLTLRSNKF 599
Cdd:PLN03150 423 LGLDNQGLRGFIPNDISKLRHLQSINLSGNSIRGNIPPSLGSITSLEVLDLSYNSFNGSIPESLGQLTSLRILNLNGNSL 502

                         90       100
                 ....*....|....*....|....*..
gi 15225775  600 YGPISpphqGPLGFPELR--IFEIADN 624
Cdd:PLN03150 503 SGRVP----AALGGRLLHraSFNFTDN 525
RNA1 COG5238
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ...
 158-328 2.56e-04

Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444072 [Multi-domain]  Cd Length: 434  Bit Score: 44.40  E-value: 2.56e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15225775 158 KLAVLDLSDNHFS--GTLNPNNSLFELHSLRYLNLAFNNISS----SLPSKFGNLNKLEVLSLSFN--GFSG--QCFPTI 227
Cdd:COG5238 237 SLTTLDLSNNQIGdeGVIALAEALKNNTTVETLYLSGNQIGAegaiALAKALQGNTTLTSLDLSVNriGDEGaiALAEGL 316

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15225775 228 SNLTRITQLYLHNNELT--GSFPLVQNL---TKLSFLGLSDNLFSG----TIPSYLFTFPSLSTLDLRENDLS--GSIEV 296
Cdd:COG5238 317 QGNKTLHTLNLAYNGIGaqGAIALAKALqenTTLHSLDLSDNQIGDegaiALAKYLEGNTTLRELNLGKNNIGkqGAEAL 396

                       170       180       190
                ....*....|....*....|....*....|..
gi 15225775 297 PNSSTSSKLEIMYLGFNHLEGKILEPISKLIN 328
Cdd:COG5238 397 IDALQTNRLHTLILDGNLIGAEAQQRLEQLLE 428
LRR_8 pfam13855
Leucine rich repeat;
158-219 2.67e-04

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 39.82  E-value: 2.67e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 15225775   158 KLAVLDLSDNHFSGTlnPNNSLFELHSLRYLNLAFNNISSSLPSKFGNLNKLEVLSLSFNGF 219
Cdd:pfam13855   2 NLRSLDLSNNRLTSL--DDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
LRR_8 pfam13855
Leucine rich repeat;
694-749 4.32e-04

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 39.04  E-value: 4.32e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 15225775   694 IDFSGNRLQGQIPESIGLLKALIALNLSNNAFTGHIPLSFANLMNLESLDMSGNQL 749
Cdd:pfam13855   6 LDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
PLN03150 PLN03150
hypothetical protein; Provisional
 259-334 1.08e-03

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 42.50  E-value: 1.08e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 15225775  259 LGLSDNLFSGTIPSYLFTFPSLSTLDLRENDLSGSIEVPNSSTSSkLEIMYLGFNHLEGKILEPISKLINLKRLDL 334
Cdd:PLN03150 423 LGLDNQGLRGFIPNDISKLRHLQSINLSGNSIRGNIPPSLGSITS-LEVLDLSYNSFNGSIPESLGQLTSLRILNL 497
LRR_8 pfam13855
Leucine rich repeat;
718-773 2.75e-03

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 36.73  E-value: 2.75e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 15225775   718 LNLSNNAFTGHIPLSFANLMNLESLDMSGNQLSGTIPNGLGSLSFLVYISVAHNKL 773
Cdd:pfam13855   6 LDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
LRR_RI cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ...
 251-435 3.18e-03

Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).


Pssm-ID: 238064 [Multi-domain]  Cd Length: 319  Bit Score: 40.42  E-value: 3.18e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15225775 251 QNLTKLSFLGLSDNLFS----GTIPSYLfTFPSLSTLDLRENDLSGSI-----EVPNSStSSKLEIMYLGFNHLEGKILE 321
Cdd:cd00116  78 TKGCGLQELDLSDNALGpdgcGVLESLL-RSSSLQELKLNNNGLGDRGlrllaKGLKDL-PPALEKLVLGRNRLEGASCE 155

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15225775 322 PISKLinlkrldlsflntsypidlnlLSPLKSLSYLDFSGNslspaslssssyiPLSMEsivlslcGIREFPNILKHLQN 401
Cdd:cd00116 156 ALAKA---------------------LRANRDLKELNLANN-------------GIGDA-------GIRALAEGLKANCN 194

                       170       180       190
                ....*....|....*....|....*....|....*...
gi 15225775 402 LIHIDITSNQIK----GKIPEWLWTLPQLSFVDISNNS 435
Cdd:cd00116 195 LEVLDLNNNGLTdegaSALAETLASLKSLEVLNLGDNN 232
LRR_8 pfam13855
Leucine rich repeat;
539-599 4.20e-03

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 36.35  E-value: 4.20e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 15225775   539 SSLKSLDVGYNRLTGKLPRSLLNCSSLRFLSVDNNRVKDTFPFWLKALPNLRVLTLRSNKF 599
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
LRR_8 pfam13855
Leucine rich repeat;
139-195 4.28e-03

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 36.35  E-value: 4.28e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 15225775   139 IDLSHNDL----MGSFplvRNLGKLAVLDLSDNHFSgTLNPnNSLFELHSLRYLNLAFNNI 195
Cdd:pfam13855   6 LDLSNNRLtsldDGAF---KGLSNLKVLDLSNNLLT-TLSP-GAFSGLPSLRYLDLSGNRL 61
LRR_8 pfam13855
Leucine rich repeat;
397-436 7.15e-03

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 35.58  E-value: 7.15e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 15225775   397 KHLQNLIHIDITSNQIKGKIPEWLWTLPQLSFVDISNNSF 436
Cdd:pfam13855  22 KGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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