|
Name |
Accession |
Description |
Interval |
E-value |
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
314-636 |
3.06e-13 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 73.43 E-value: 3.06e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 314 APPRPSVTAAEPMNSAAPPRPSVTAAEPMNSTAPP-RPSVTAAEAT------------PPNLSAPLPHCNTPQ-PSPISQ 379
Cdd:PHA03247 2646 VPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPqRPRRRAARPTvgsltsladpppPPPTPEPAPHALVSAtPLPPGP 2725
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 380 QAAVESNTQMQSTALPRPSVTAEA-----RPLHQPHSNTSQPRPIPQQALAqSNTNITSTALPRPSITAEARLLHQPHSN 454
Cdd:PHA03247 2726 AAARQASPALPAAPAPPAVPAGPAtpggpARPARPPTTAGPPAPAPPAAPA-AGPPRRLTRPAVASLSESRESLPSPWDP 2804
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 455 TPQPRPIPQKALVQANTDINSTALPRPLVTAEAPPlhqSSCKAPQPKPISQQPAVQSKTDIiNSTALPRPSVTTEARPLH 534
Cdd:PHA03247 2805 ADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAP---PPPPGPPPPSLPLGGSVAPGGDV-RRRPPSRSPAAKPAAPAR 2880
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 535 QPRSKTPQPkPVSQPPAKQSNTEINSTPHPRPSVTSKAI---SLQSPPCNTPQPRPPPLISNHTPTSYQPASAPPVHGIA 611
Cdd:PHA03247 2881 PPVRRLARP-AVSRSTESFALPPDQPERPPQPQAPPPPQpqpQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAV 2959
|
330 340 350
....*....|....*....|....*....|....*..
gi 42569409 612 R----------RTMAPHLR--SSRAPNSAAAPSTYPR 636
Cdd:PHA03247 2960 PqpwlgalvpgRVAVPRFRvpQPAPSREAPASSTPPL 2996
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
277-654 |
5.15e-13 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 73.05 E-value: 5.15e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 277 PVKSAATDTATVRAPRSSQHSTQQQQAVQTNRHMNSTAPPRPSVTAAEPMNSAAPPRPSVTAAEPMNSTAPPRPSVT--- 353
Cdd:PHA03247 2554 PLPPAAPPAAPDRSVPPPRPAPRPSEPAVTSRARRPDAPPQSARPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSpsp 2633
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 354 AAEATPPNLSAPLPHCNTPQPSPISQQAAVESNTQMQSTALPRPSVTAEARPLHQPH---SNTSQPRPIPQQALAQSNTN 430
Cdd:PHA03247 2634 AANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPtvgSLTSLADPPPPPPTPEPAPH 2713
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 431 ITSTALPRPSITAEARLLHQPHSNTPQPRPIPQKALvqanTDINSTALPRPLVTAEAPPLHQSSCKAPQPKPISQQPAVQ 510
Cdd:PHA03247 2714 ALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPA----TPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVA 2789
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 511 SKTDIINSTALPR----------------PSVTTEARPLHQPRSKTPQPKPVS----------------------QPPAK 552
Cdd:PHA03247 2790 SLSESRESLPSPWdpadppaavlapaaalPPAASPAGPLPPPTSAQPTAPPPPpgppppslplggsvapggdvrrRPPSR 2869
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 553 QSNTEINSTPHP------RPSVTSKAISLQSPPCNTPQPRPPPLISNHTPTSYQPASAPPvhgiarrtmAPHLRSSRAPN 626
Cdd:PHA03247 2870 SPAAKPAAPARPpvrrlaRPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQP---------QPPPPPPPRPQ 2940
|
410 420
....*....|....*....|....*...
gi 42569409 627 SAAAPSTYPRLAQEQQKQQQKKSNSSLV 654
Cdd:PHA03247 2941 PPLAPTTDPAGAGEPSGAVPQPWLGALV 2968
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
309-608 |
1.07e-11 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 68.43 E-value: 1.07e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 309 HMNSTAPPRPSVTAAE------PMNSAAPPRPSVTAAEPMNSTAPPRPSVTAA--EATPPNLSAPLPHCNTPQPSPISQQ 380
Cdd:PHA03247 2713 HALVSATPLPPGPAAArqaspaLPAAPAPPAVPAGPATPGGPARPARPPTTAGppAPAPPAAPAAGPPRRLTRPAVASLS 2792
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 381 AAVESNTQMQSTALPRPSVTAEARPLhqPHSNTSQPRPIPQQALAQSNTNITSTALPRPSITAEARLLHQPHSNTPQPRP 460
Cdd:PHA03247 2793 ESRESLPSPWDPADPPAAVLAPAAAL--PPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPGGDVRRRPPSRS 2870
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 461 IPQKALVQANTDINSTALPRPLVTAEAPPLHQSScKAPQPKPISQQPAVQSKTDiiNSTALPRPSVTTEARPlHQPRSKT 540
Cdd:PHA03247 2871 PAAKPAAPARPPVRRLARPAVSRSTESFALPPDQ-PERPPQPQAPPPPQPQPQP--PPPPQPQPPPPPPPRP-QPPLAPT 2946
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 42569409 541 PQPKPVSQPPAKQSNTEINSTPHPRPSVTSKAISLQSPPCNTPQPRPPPLISNHTPTSYQPASAPPVH 608
Cdd:PHA03247 2947 TDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPQPAPSREAPASSTPPLTGHSLSRVSSWASSLALH 3014
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
269-606 |
1.04e-08 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 58.80 E-value: 1.04e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 269 ANAYKSTCPVKSAATDTATVRAPRSSQHSTQQQQAVQTNRHMNSTAPPRPSVTAAEPMNSAAPPRPSVTAAEPmnsTAPP 348
Cdd:PHA03247 2764 AGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQP---TAPP 2840
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 349 RPSVTAAEATPPNLSAPLPHCNTPQPSPISQQAAVESNTQMQSTALPRPSVTAEARPLHQPhsnTSQPRPIPQQALAQSn 428
Cdd:PHA03247 2841 PPPGPPPPSLPLGGSVAPGGDVRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALP---PDQPERPPQPQAPPP- 2916
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 429 tnitstalPRPSITAEARLLHQPHSNTP-QPRPIPQKALVQANTDINSTALPRPLVTAEAPPLHQ-SSCKAPQPKPISQQ 506
Cdd:PHA03247 2917 --------PQPQPQPPPPPQPQPPPPPPpRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAvPRFRVPQPAPSREA 2988
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 507 PAVQSKTdiinSTALPRPSVTTEARPLHQPRSKTPQPKPVSQPPAKQSNTEINSTPHPRPSvTSKAISLQSPPCNTPQPR 586
Cdd:PHA03247 2989 PASSTPP----LTGHSLSRVSSWASSLALHEETDPPPVSLKQTLWPPDDTEDSDADSLFDS-DSERSDLEALDPLPPEPH 3063
|
330 340
....*....|....*....|
gi 42569409 587 PPPLISNHTPTSYQPASAPP 606
Cdd:PHA03247 3064 DPFAHEPDPATPEAGARESP 3083
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
312-653 |
1.97e-08 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 58.03 E-value: 1.97e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 312 STAPPRPSVTAAEPMNSAAPPRPSVTAA-----EPMNSTAPPR-----------PSVTAAEATPPNLSAPLP-----HCN 370
Cdd:PHA03247 2490 FAAGAAPDPGGGGPPDPDAPPAPSRLAPailpdEPVGEPVHPRmltwirgleelASDDAGDPPPPLPPAAPPaapdrSVP 2569
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 371 TPQPSPISQQAAVESNTQmqstalpRPSVTAEARPLHQPHSNTSQPRPIPQQALAQSNTNITSTALPRPSITAEARLLHQ 450
Cdd:PHA03247 2570 PPRPAPRPSEPAVTSRAR-------RPDAPPQSARPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHP 2642
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 451 PHSNTPQPRPIPQKALVQANTDINSTALPRPlVTAEAPPlhqssckaPQPKPISQQPAVQSKTDIIN-----STALPRPS 525
Cdd:PHA03247 2643 PPTVPPPERPRDDPAPGRVSRPRRARRLGRA-AQASSPP--------QRPRRRAARPTVGSLTSLADpppppPTPEPAPH 2713
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 526 VTTEARPL----HQPRSKTPQP--KPVSQPPAKQSNTEINSTPHPRPSVTSKAISLQSP--PCNTPQPR-PPPLISNHTP 596
Cdd:PHA03247 2714 ALVSATPLppgpAAARQASPALpaAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPaaPAAGPPRRlTRPAVASLSE 2793
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*....
gi 42569409 597 T--SYQPASAPPVHGIARRTMAPHLRSSRAPNSAAAPSTYPRLAQEQQKQQQKKSNSSL 653
Cdd:PHA03247 2794 SreSLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPL 2852
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
313-606 |
8.87e-07 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 52.46 E-value: 8.87e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 313 TAPPRPSVTAAEPMNSAAPPRPSVTAAEPMNSTAPPRPSVTAAEATPPNLSAPLPHCNTP-----QPSPISQQAAVESNT 387
Cdd:pfam03154 189 PGTTQAATAGPTPSAPSVPPQGSPATSQPPNQTQSTAAPHTLIQQTPTLHPQRLPSPHPPlqpmtQPPPPSQVSPQPLPQ 268
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 388 QMQSTALPRPSVTAEARPLHQPHSNTSQPRPIPQQALAQSNTNITSTALPRPSITAEARLLHQPHSNTPQP---RPIPQK 464
Cdd:pfam03154 269 PSLHGQMPPMPHSLQTGPSHMQHPVPPQPFPLTPQSSQSQVPPGPSPAAPGQSQQRIHTPPSQSQLQSQQPpreQPLPPA 348
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 465 ALVQANTDINSTALPRPLVTAEA--PPLHQSSCKAPQ-----PKPISQQPAVQSKTDIINSTALPRPSVTTEARPLHQPR 537
Cdd:pfam03154 349 PLSMPHIKPPPTTPIPQLPNPQShkHPPHLSGPSPFQmnsnlPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQQLPPPP 428
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 42569409 538 SKTPQPKPVSQPPAKQSNTEINSTPHPRPS---VTSKAISLQSPPCNTPQPRPPPLISNHTPTSYQPASAPP 606
Cdd:pfam03154 429 AQPPVLTQSQSLPPPAASHPPTSGLHQVPSqspFPQHPFVPGGPPPITPPSGPPTSTSSAMPGIQPPSSASV 500
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
277-593 |
1.09e-05 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 49.17 E-value: 1.09e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 277 PVKSAATDTATVRAPRSSQHST----QQQQAVQTNRHMNSTAPPRPSVTAAEPMNSAAPPRPS------VTAAEPMNSTA 346
Cdd:PHA03247 2787 AVASLSESRESLPSPWDPADPPaavlAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSlplggsVAPGGDVRRRP 2866
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 347 PPRPSVT--AAEATPPNLSAPLPHCNTPQPSPISQQAAVESNTQMQSTALPRPSVTAEARPLHQPHSNT-SQPRPIPQQA 423
Cdd:PHA03247 2867 PSRSPAAkpAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPpPRPQPPLAPT 2946
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 424 LAQSNTNITSTALPRPSITAEAR-LLHQPHSNTPQPRPiPQKALVQANTDINSTALPRPLVTAEAPPLHQSsckaPQPKP 502
Cdd:PHA03247 2947 TDPAGAGEPSGAVPQPWLGALVPgRVAVPRFRVPQPAP-SREAPASSTPPLTGHSLSRVSSWASSLALHEE----TDPPP 3021
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 503 ISQQPAVQSKTDIINSTALPRPSVTTEARPLHQPrskTPQPKPVSQPPAkqsnteinstpHPRPSVTSKAISLQSPpcnT 582
Cdd:PHA03247 3022 VSLKQTLWPPDDTEDSDADSLFDSDSERSDLEAL---DPLPPEPHDPFA-----------HEPDPATPEAGARESP---S 3084
|
330
....*....|.
gi 42569409 583 PQPRPPPLISN 593
Cdd:PHA03247 3085 SQFGPPPLSAN 3095
|
|
| PRK10263 |
PRK10263 |
DNA translocase FtsK; Provisional |
357-635 |
1.25e-05 |
|
DNA translocase FtsK; Provisional
Pssm-ID: 236669 [Multi-domain] Cd Length: 1355 Bit Score: 48.54 E-value: 1.25e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 357 ATPPNLSAPLPHCN-TPQPSPISQQAAVESNTQMQSTA----LPRPSVTAEARPLHQPHSNTsQPRPIPQQalaqsntni 431
Cdd:PRK10263 299 ATQPEYDEYDPLLNgAPITEPVAVAAAATTATQSWAAPvepvTQTPPVASVDVPPAQPTVAW-QPVPGPQT--------- 368
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 432 tstalPRPSItAEARLLHQPHSNTPQPRPIPQKALVQANTDINSTALPRPLVTAEAP---PLHQSSCKAPQPKPISQQPA 508
Cdd:PRK10263 369 -----GEPVI-APAPEGYPQQSQYAQPAVQYNEPLQQPVQPQQPYYAPAAEQPAQQPyyaPAPEQPAQQPYYAPAPEQPV 442
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 509 VQsktdiiNSTALPRPSVTTEARPLHQPRSktPQPKPVSQPPAKQSNTEINSTPHPRPSVTSKAISLQSPPC-------- 580
Cdd:PRK10263 443 AG------NAWQAEEQQSTFAPQSTYQTEQ--TYQQPAAQEPLYQQPQPVEQQPVVEPEPVVEETKPARPPLyyfeevee 514
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 581 --------------NTPQPRPPPLISNHTPTSYQPASAPPVHGIAR-RTMAPHLRSSRAPNSAAAPSTYP 635
Cdd:PRK10263 515 krarereqlaawyqPIPEPVKEPEPIKSSLKAPSVAAVPPVEAAAAvSPLASGVKKATLATGAAATVAAP 584
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
312-636 |
2.57e-05 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 47.67 E-value: 2.57e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 312 STAPPRPSVTAAEPMNSAAPPRPSVTAAEPMNSTAPPRPSVTAAEATPPNLSAPLPHCNTPQPSPISQQAAVESNTQMQS 391
Cdd:PRK07764 404 AAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPAAAPSAQPAPAPAAAPEPTAAPAPA 483
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 392 TALPRPSVTAEARPLHQPHSNTSQPRPIPQQALAQ-----SNTNITSTALprpsITAEARlLHQPHSNTPQ---PRPIPQ 463
Cdd:PRK07764 484 PPAAPAPAAAPAAPAAPAAPAGADDAATLRERWPEilaavPKRSRKTWAI----LLPEAT-VLGVRGDTLVlgfSTGGLA 558
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 464 KALVQA-NTDINSTALPRPL-----VTAEAPPlhqssckAPQPKPISQQPAVQsktdiinstalPRPSVTTEARPLHQPR 537
Cdd:PRK07764 559 RRFASPgNAEVLVTALAEELggdwqVEAVVGP-------APGAAGGEGPPAPA-----------SSGPPEEAARPAAPAA 620
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 538 SKTPQPKPVSQPPAKQSNTEINSTPHPRPSVTSKAISLQSPPCNTPQPRPPPlISNHTPTSYQPASAPPVHGIARRTMAP 617
Cdd:PRK07764 621 PAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAK-AGGAAPAAPPPAPAPAAPAAPAGAAPA 699
|
330
....*....|....*....
gi 42569409 618 HLRSSRAPNSAAAPSTYPR 636
Cdd:PRK07764 700 QPAPAPAATPPAGQADDPA 718
|
|
| Herpes_BLLF1 |
pfam05109 |
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ... |
271-530 |
2.63e-05 |
|
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.
Pssm-ID: 282904 [Multi-domain] Cd Length: 886 Bit Score: 47.60 E-value: 2.63e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 271 AYKSTCPVKSAATDTATVRAPRSSQHSTQQQQAVQTNRHMNSTAPPRPSVTAA--EPMNSAAPPRPSVTAAEPmNSTAPP 348
Cdd:pfam05109 460 APASTGPTVSTADVTSPTPAGTTSGASPVTPSPSPRDNGTESKAPDMTSPTSAvtTPTPNATSPTPAVTTPTP-NATSPT 538
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 349 --RPSVTAAEATP-PNLSAPLPHCNTPQPSPISQQAAVESNTQMQSTalPRPSVTAEARPLHQPHSNTSqprpipQQALA 425
Cdd:pfam05109 539 lgKTSPTSAVTTPtPNATSPTPAVTTPTPNATIPTLGKTSPTSAVTT--PTPNATSPTVGETSPQANTT------NHTLG 610
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 426 QSNTNITSTALPRPSITAEARLLHQPHSNTPQP---RPIPQKALVQANTDINSTAlPRPLVTAEAPPLHQSSCKApqpkp 502
Cdd:pfam05109 611 GTSSTPVVTSPPKNATSAVTTGQHNITSSSTSSmslRPSSISETLSPSTSDNSTS-HMPLLTSAHPTGGENITQV----- 684
|
250 260
....*....|....*....|....*...
gi 42569409 503 isqQPAVQSKTDIINSTALPRPSVTTEA 530
Cdd:pfam05109 685 ---TPASTSTHHVSTSSPAPRPGTTSQA 709
|
|
| PHA03378 |
PHA03378 |
EBNA-3B; Provisional |
331-607 |
5.67e-05 |
|
EBNA-3B; Provisional
Pssm-ID: 223065 [Multi-domain] Cd Length: 991 Bit Score: 46.60 E-value: 5.67e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 331 PPRPSVTAAEPMNSTAPPRPSVTAAEATPPNLSAPLPhcnTPQPSPISQQAAVESNTQMQSTALPrpsvTAEARPLHQPH 410
Cdd:PHA03378 529 PPQPRAGRRAPCVYTEDLDIESDEPASTEPVHDQLLP---APGLGPLQIQPLTSPTTSQLASSAP----SYAQTPWPVPH 601
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 411 SNTSqPRPIPQQALAQSNTNITSTALPRPSITAEArLLHQPHSNTPQPRPIPQKALVQANTDINSTALPRPLVTAEAPPL 490
Cdd:PHA03378 602 PSQT-PEPPTTQSHIPETSAPRQWPMPLRPIPMRP-LRMQPITFNVLVFPTPHQPPQVEITPYKPTWTQIGHIPYQPSPT 679
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 491 HQSSCKAPQPKPISQQPAVQSKTdiinstalPRPSVTTEARPLHQPRSKTPQPKPVSQPPAKQSNTEINSTPHPRPSVTS 570
Cdd:PHA03378 680 GANTMLPIQWAPGTMQPPPRAPT--------PMRPPAAPPGRAQRPAAATGRARPPAAAPGRARPPAAAPGRARPPAAAP 751
|
250 260 270
....*....|....*....|....*....|....*..
gi 42569409 571 KAISlqsPPCNTPQPRPPPLISNHTPTSYQPASAPPV 607
Cdd:PHA03378 752 GRAR---PPAAAPGRARPPAAAPGAPTPQPPPQAPPA 785
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
334-601 |
8.12e-05 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 45.91 E-value: 8.12e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 334 PSVTAAEPMNSTAPPRPSVTAAEATPPNLSAPLPHCNTPQPSPISQQAAvesntqmqSTALPRPSVTAEARplhQPHSNT 413
Cdd:pfam03154 146 PSIPSPQDNESDSDSSAQQQILQTQPPVLQAQSGAASPPSPPPPGTTQA--------ATAGPTPSAPSVPP---QGSPAT 214
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 414 SQPrPIPQQALAQSNTNITSTALPRPSITAEARLLHQPHSNTPQPRPIPQKALVQANTDINSTALPRPLvtaEAPPLHQS 493
Cdd:pfam03154 215 SQP-PNQTQSTAAPHTLIQQTPTLHPQRLPSPHPPLQPMTQPPPPSQVSPQPLPQPSLHGQMPPMPHSL---QTGPSHMQ 290
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 494 SCKAPQPKPISQQPAvQSKTDIINSTALPRPSVTTEARPLHQPRSKTPQ-PKPVSQPPAKQSNTEINSTP---------- 562
Cdd:pfam03154 291 HPVPPQPFPLTPQSS-QSQVPPGPSPAAPGQSQQRIHTPPSQSQLQSQQpPREQPLPPAPLSMPHIKPPPttpipqlpnp 369
|
250 260 270 280
....*....|....*....|....*....|....*....|...
gi 42569409 563 --HPRPSVTSKAISLQSPPCNTPQPRPPPL--ISNHTPTSYQP 601
Cdd:pfam03154 370 qsHKHPPHLSGPSPFQMNSNLPPPPALKPLssLSTHHPPSAHP 412
|
|
| PAT1 |
pfam09770 |
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ... |
330-508 |
1.11e-04 |
|
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.
Pssm-ID: 401645 [Multi-domain] Cd Length: 846 Bit Score: 45.41 E-value: 1.11e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 330 APPRPSVTAAEPMNSTAPPRPSVTA--------------AEATPPNLSAPLPHCNTPQPSPISQQAAVesntQMQSTALP 395
Cdd:pfam09770 166 APKKAAAPAPAPQPAAQPASLPAPSrkmmsleeveaamrAQAKKPAQQPAPAPAQPPAAPPAQQAQQQ----QQFPPQIQ 241
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 396 RPSVTAEARPLHQPHSNTSQPRPIPQQALAQSNTNITSTALPRPSItaearLLHQPHSNTPQPRPIPQKALVQANTDINS 475
Cdd:pfam09770 242 QQQQPQQQPQQPQQHPGQGHPVTILQRPQSPQPDPAQPSIQPQAQQ-----FHQQPPPVPVQPTQILQNPNRLSAARVGY 316
|
170 180 190
....*....|....*....|....*....|....
gi 42569409 476 TALPRPLVTAEAP-PLHQSSCKAPQPKPISQQPA 508
Cdd:pfam09770 317 PQNPQPGVQPAPAhQAHRQQGSFGRQAPIITHPQ 350
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
316-447 |
1.65e-04 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 44.71 E-value: 1.65e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 316 PRPSVTAAEPMNSAAPPRPSvtAAEPMNSTAPPRPSVTAAEATPPNLSAPLPHCNTPQPSPISQQAAVESNtqmqsTALP 395
Cdd:PRK14951 366 PAAAAEAAAPAEKKTPARPE--AAAPAAAPVAQAAAAPAPAAAPAAAASAPAAPPAAAPPAPVAAPAAAAP-----AAAP 438
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 42569409 396 RPSVTAEARPLHQPHSNTSQPRPIPQQalAQSNTNITSTALPRPSITAEARL 447
Cdd:PRK14951 439 AAAPAAVALAPAPPAQAAPETVAIPVR--VAPEPAVASAAPAPAAAPAAARL 488
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
309-602 |
2.40e-04 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 44.37 E-value: 2.40e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 309 HMNSTAPPRPSVTAAEPMNSAAPPRPSVTAAEPMNSTAPPRPSVTAAEATPPNLSAPL-------PHCNTPQPSPISQQA 381
Cdd:pfam03154 288 HMQHPVPPQPFPLTPQSSQSQVPPGPSPAAPGQSQQRIHTPPSQSQLQSQQPPREQPLppaplsmPHIKPPPTTPIPQLP 367
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 382 AVESNTQMQSTALPRPSvtaearplhqpHSNTSQPRPIPQQALAQSNTNITSTALPRPsitaearLLHQPHSNTPQPRPI 461
Cdd:pfam03154 368 NPQSHKHPPHLSGPSPF-----------QMNSNLPPPPALKPLSSLSTHHPPSAHPPP-------LQLMPQSQQLPPPPA 429
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 462 PQKALVQANTdinstalpRPLVTAEAPPLHQSSCKAPQPkPISQQPAVQSKTDIINSTALPRPSVTTEARPLHQPRSKTP 541
Cdd:pfam03154 430 QPPVLTQSQS--------LPPPAASHPPTSGLHQVPSQS-PFPQHPFVPGGPPPITPPSGPPTSTSSAMPGIQPPSSASV 500
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 42569409 542 QpkpvSQPPAKQSNTEINSTPHPRPSVTSKAISLQSPPCNTPQPRPPPLISNHTPTSYQPA 602
Cdd:pfam03154 501 S----SSGPVPAAVSCPLPPVQIKEEALDEAEEPESPPPPPRSPSPEPTVVNTPSHASQSA 557
|
|
| Herpes_BLLF1 |
pfam05109 |
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ... |
290-626 |
2.71e-04 |
|
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.
Pssm-ID: 282904 [Multi-domain] Cd Length: 886 Bit Score: 44.14 E-value: 2.71e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 290 APRSSQHSTQQQQAVQTNRHMNSTAPPRpSVTAAEPMNSAAPPRPSVTAA------EPMNSTAPPR--PSVTAAEATPPN 361
Cdd:pfam05109 399 APKTLIITRTATNATTTTHKVIFSKAPE-STTTSPTLNTTGFAAPNTTTGlpssthVPTNLTAPAStgPTVSTADVTSPT 477
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 362 LSAPLPHCNTPQPSPISQQAAVESNTqmqstalprPSVTAEARPLHQPHSNTSQPRPipqqALAQSNTNITSTALPRPSI 441
Cdd:pfam05109 478 PAGTTSGASPVTPSPSPRDNGTESKA---------PDMTSPTSAVTTPTPNATSPTP----AVTTPTPNATSPTLGKTSP 544
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 442 TAeARLLHQPHSNTPQP---RPIPQKALVQANTDINSTALPRPLVTAEAPPLHQSSckaPQPKPISQQPAVQSKTDIINS 518
Cdd:pfam05109 545 TS-AVTTPTPNATSPTPavtTPTPNATIPTLGKTSPTSAVTTPTPNATSPTVGETS---PQANTTNHTLGGTSSTPVVTS 620
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 519 TALPRPS-VTTEARPLHQPRSKTPQPKPVSQPPAKQSNTEINSTPH------PRPS-------VTSKAISLQSPPCNTPQ 584
Cdd:pfam05109 621 PPKNATSaVTTGQHNITSSSTSSMSLRPSSISETLSPSTSDNSTSHmplltsAHPTggenitqVTPASTSTHHVSTSSPA 700
|
330 340 350 360
....*....|....*....|....*....|....*....|..
gi 42569409 585 PRPPPLISNHTPTSYQPASAPPVHGIARRTMAPHLRSSRAPN 626
Cdd:pfam05109 701 PRPGTTSQASGPGNSSTSTKPGEVNVTKGTPPKNATSPQAPS 742
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
312-659 |
3.20e-04 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 44.01 E-value: 3.20e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 312 STAPPRPSVTAAEPMNSAAPPRPSVTAAEPmNSTAPPRPSVTAAEATPPNLSAPLPHCNTPQPSPISQQAAVESNTQMQS 391
Cdd:PHA03307 113 SPDPPPPTPPPASPPPSPAPDLSEMLRPVG-SPGPPPAASPPAAGASPAAVASDAASSRQAALPLSSPEETARAPSSPPA 191
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 392 TALPRPSVTAEARPLHQPHSNTSQPRPIPQQALAQSNTNITSTALPRPSITAEARLLHQPHSNTPQPRPIPQKALVQANT 471
Cdd:PHA03307 192 EPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRSAADDAGASSSDSSSSESSGCGWGPENECPLPRPAPITLPTRIWE 271
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 472 DINSTALPRPLVTAEAPPLHQSSCKAPQPkPISQQPAVQSKTDIINSTALPRPSVTTEARPLHQPRSKTPQPKPVSqppa 551
Cdd:PHA03307 272 ASGWNGPSSRPGPASSSSSPRERSPSPSP-SSPGSGPAPSSPRASSSSSSSRESSSSSTSSSSESSRGAAVSPGPS---- 346
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 552 kqsnteinSTPHPRPSVTSkaislQSPPCNTPQPRPPPLISNHTPTSYQPASAPPVhgiARRTMAPHLRSSRAPNSAAAP 631
Cdd:PHA03307 347 --------PSRSPSPSRPP-----PPADPSSPRKRPRPSRAPSSPAASAGRPTRRR---ARAAVAGRARRRDATGRFPAG 410
|
330 340
....*....|....*....|....*...
gi 42569409 632 STYPRLAQEQQKQQQKKSNSSLVYLSDD 659
Cdd:PHA03307 411 RPRPSPLDAGAASGAFYARYPLLTPSGE 438
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
318-604 |
3.35e-04 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 44.07 E-value: 3.35e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 318 PSVTAAEPMNSAAPPRPSV--------TAAEPMNSTAPPRPSVTAAEATPPNLSAPLPHCNTPQPSPISQQAAVESNTQM 389
Cdd:PRK07003 360 PAVTGGGAPGGGVPARVAGavpapgarAAAAVGASAVPAVTAVTGAAGAALAPKAAAAAAATRAEAPPAAPAPPATADRG 439
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 390 QSTALPRPSVTAEArplhqphSNTSQPRPIPQQALAQSNTNITSTALPRPSITAEARllhqphsNTPQPR--PIPQKALV 467
Cdd:PRK07003 440 DDAADGDAPVPAKA-------NARASADSRCDERDAQPPADSGSASAPASDAPPDAA-------FEPAPRaaAPSAATPA 505
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 468 QANTDINSTALPRPlvtAEAPPLHQSSCKAPQPKPISQQPAVQS-----KTDIINSTALpRPSVTTEARPLHQPRSKTPQ 542
Cdd:PRK07003 506 AVPDARAPAAASRE---DAPAAAAPPAPEARPPTPAAAAPAARAggaaaALDVLRNAGM-RVSSDRGARAAAAAKPAAAP 581
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 42569409 543 PkPVSQPPAKQSNTEINSTPHPRPSVTSKAISLQSPPCNTPQPRPPPLISNHTPTSYQPASA 604
Cdd:PRK07003 582 A-AAPKPAAPRVAVQVPTPRARAATGDAPPNGAARAEQAAESRGAPPPWEDIPPDDYVPLSA 642
|
|
| PRK10263 |
PRK10263 |
DNA translocase FtsK; Provisional |
268-553 |
4.85e-04 |
|
DNA translocase FtsK; Provisional
Pssm-ID: 236669 [Multi-domain] Cd Length: 1355 Bit Score: 43.54 E-value: 4.85e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 268 LANAYKSTCPVKSAATDTATVR---APRSSQHSTQQQQAVQTNRHMNSTA-PPRPSVTAAEPMNSAAP---------PRP 334
Cdd:PRK10263 310 LLNGAPITEPVAVAAAATTATQswaAPVEPVTQTPPVASVDVPPAQPTVAwQPVPGPQTGEPVIAPAPegypqqsqyAQP 389
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 335 SVTAAEPMNSTAPPRPSVTAAEATPPNLS---APLPHCNTPQPSPISQQAAVESNTQMQStalPRPSVTAEARPLHQPHS 411
Cdd:PRK10263 390 AVQYNEPLQQPVQPQQPYYAPAAEQPAQQpyyAPAPEQPAQQPYYAPAPEQPVAGNAWQA---EEQQSTFAPQSTYQTEQ 466
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 412 NTSQP----------RPIPQQALAQSNTNITSTALPRPSI----TAEARLLHQPHSNTPQPRPIPQKalVQANTDINSTA 477
Cdd:PRK10263 467 TYQQPaaqeplyqqpQPVEQQPVVEPEPVVEETKPARPPLyyfeEVEEKRAREREQLAAWYQPIPEP--VKEPEPIKSSL 544
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 478 lpRPLVTAEAPPLHQSSCKAPQPKPISQQPAVQSKTdiiNSTALPRPSVTTEARPLHQPRS----KTPQPKPVSQPPAKQ 553
Cdd:PRK10263 545 --KAPSVAAVPPVEAAAAVSPLASGVKKATLATGAA---ATVAAPVFSLANSGGPRPQVKEgigpQLPRPKRIRVPTRRE 619
|
|
| PRK13042 |
PRK13042 |
superantigen-like protein SSL4; Reviewed; |
306-390 |
5.10e-04 |
|
superantigen-like protein SSL4; Reviewed;
Pssm-ID: 183854 [Multi-domain] Cd Length: 291 Bit Score: 42.70 E-value: 5.10e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 306 TNRHMNSTAPPRPSVTAAEpmnsAAPPRPSVTAAEPM-NSTAPPRPSVTAAEATPPNLSAPLPHCNTPQpSPISQQAAVE 384
Cdd:PRK13042 24 TTQAANATTPSSTKVEAPQ----STPPSTKVEAPQSKpNATTPPSTKVEAPQQTPNATTPSSTKVETPQ-SPTTKQVPTE 98
|
....*.
gi 42569409 385 SNTQMQ 390
Cdd:PRK13042 99 INPKFK 104
|
|
| PRK13335 |
PRK13335 |
superantigen-like protein SSL3; Reviewed; |
469-600 |
5.19e-04 |
|
superantigen-like protein SSL3; Reviewed;
Pssm-ID: 139494 [Multi-domain] Cd Length: 356 Bit Score: 42.81 E-value: 5.19e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 469 ANTDINSTALPRplvtaEAPPLHQSSCKAPQPKPISQQPAVQSKTdiinsTALPRPSVTTEARPLHQPRSKTPQPKpVSQ 548
Cdd:PRK13335 66 ANTRQERTPKLE-----KAPNTNEEKTSASKIEKISQPKQEEQKS-----LNISATPAPKQEQSQTTTESTTPKTK-VTT 134
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*.
gi 42569409 549 PPakqsnteinSTPHPRPSVTSKAISLQSPPCNTPQ----PRPPPLISNHTPTSYQ 600
Cdd:PRK13335 135 PP---------STNTPQPMQSTKSDTPQSPTIKQAQtdmtPKYEDLRAYYTKPSFE 181
|
|
| PRK07994 |
PRK07994 |
DNA polymerase III subunits gamma and tau; Validated |
317-525 |
7.22e-04 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236138 [Multi-domain] Cd Length: 647 Bit Score: 42.55 E-value: 7.22e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 317 RPSVTAAEpmnsaaPPRPSVTAAEPMNSTAPPRPSVTAAEATPPNLSAPlphcntPQPSPISQQAAVESNtqmqstalPR 396
Cdd:PRK07994 360 HPAAPLPE------PEVPPQSAAPAASAQATAAPTAAVAPPQAPAVPPP------PASAPQQAPAVPLPE--------TT 419
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 397 PSVTAEARPLHQPHSNTSQPRPIPQQALAQSNTNITSTALPRPSITAEARLLHQPHSNTPQPRPiPQKALVQANTDINST 476
Cdd:PRK07994 420 SQLLAARQQLQRAQGATKAKKSEPAAASRARPVNSALERLASVRPAPSALEKAPAKKEAYRWKA-TNPVEVKKEPVATPK 498
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 42569409 477 ALPRPLVTAEAPPLhqssckapQPKPISQQPAVQSKTDIINSTALPRPS 525
Cdd:PRK07994 499 ALKKALEHEKTPEL--------AAKLAAEAIERDPWAALVSQLGLPGLV 539
|
|
| PRK08691 |
PRK08691 |
DNA polymerase III subunits gamma and tau; Validated |
381-588 |
8.04e-04 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236333 [Multi-domain] Cd Length: 709 Bit Score: 42.77 E-value: 8.04e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 381 AAVESNTQMQSTALPRPSVTAEARPlhqphSNTSQPRPIPQQALAQSNTNITSTALPRPSITAEARLLHQPHSNTPQPRP 460
Cdd:PRK08691 364 ASCDANAVIENTELQSPSAQTAEKE-----TAAKKPQPRPEAETAQTPVQTASAAAMPSEGKTAGPVSNQENNDVPPWED 438
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 461 IPQKALVQANTDINSTALPRPLVTAEAPPLHQSS-------------CKAPQPKPISQQP---AVQSKTDIINSTALPRP 524
Cdd:PRK08691 439 APDEAQTAAGTAQTSAKSIQTASEAETPPENQVSknkaadnetdaplSEVPSENPIQATPndeAVETETFAHEAPAEPFY 518
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 42569409 525 SVTTearplhqPRSKTPQPKPVSQPPAKQSNTEINSTPHPRPSVTSKAISLQSPPcnTPQPRPP 588
Cdd:PRK08691 519 GYGF-------PDNDCPPEDGAEIPPPDWEHAAPADTAGGGADEEAEAGGIGGNN--TPSAPPP 573
|
|
| PRK14971 |
PRK14971 |
DNA polymerase III subunit gamma/tau; |
541-625 |
8.22e-04 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237874 [Multi-domain] Cd Length: 614 Bit Score: 42.46 E-value: 8.22e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 541 PQPKPVSQPPAKQSNTEINSTPHPRPSVTSKAISlqSPPCNTPQPRPPPLisnhTPTSYQPASAPPVHGIARRTMAPHLR 620
Cdd:PRK14971 390 PQPSAAAAASPSPSQSSAAAQPSAPQSATQPAGT--PPTVSVDPPAAVPV----NPPSTAPQAVRPAQFKEEKKIPVSKV 463
|
....*
gi 42569409 621 SSRAP 625
Cdd:PRK14971 464 SSLGP 468
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
269-435 |
1.27e-03 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 42.17 E-value: 1.27e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 269 ANAYKSTCPVKSAATDTATVRAPRSSQHSTQQQQAVQTNRHMNSTAPPRPSVTAAepmnsAAPPRPSVTAAEPmnstAPP 348
Cdd:PRK12323 422 APARRSPAPEALAAARQASARGPGGAPAPAPAPAAAPAAAARPAAAGPRPVAAAA-----AAAPARAAPAAAP----APA 492
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 349 RPSVTAAEATPPNLSAPLPHCNTPQPSPISQQAAVESNTQMQSTALPRPSVTAEARPLHQPHSNTSQPRPIPQQALAQSN 428
Cdd:PRK12323 493 DDDPPPWEELPPEFASPAPAQPDAAPAGWVAESIPDPATADPDDAFETLAPAPAAAPAPRAAAATEPVVAPRPPRASASG 572
|
....*..
gi 42569409 429 TNITSTA 435
Cdd:PRK12323 573 LPDMFDG 579
|
|
| PAT1 |
pfam09770 |
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ... |
379-594 |
1.37e-03 |
|
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.
Pssm-ID: 401645 [Multi-domain] Cd Length: 846 Bit Score: 41.95 E-value: 1.37e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 379 QQAAVESNTQMQSTALPRPSVTAEARPLHQPHS-------NTSQPRPIP-------------QQALAQSNTNITSTALPR 438
Cdd:pfam09770 106 QPAARAAQSSAQPPASSLPQYQYASQQSQQPSKpvrtgyeKYKEPEPIPdlqvdaslwgvapKKAAAPAPAPQPAAQPAS 185
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 439 PSITA---------EARLLHQPHSNTPQPRPIPQKALVQANTDINSTALPRPLVTAEAPPLHQSSCKAPQPKPISQQPAV 509
Cdd:pfam09770 186 LPAPSrkmmsleevEAAMRAQAKKPAQQPAPAPAQPPAAPPAQQAQQQQQFPPQIQQQQQPQQQPQQPQQHPGQGHPVTI 265
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 510 QSKTDIINSTALPRPSVTTEARPLHQPRSKTPQPKPVSQPPAKQSNTEINSTPHPRPSVTSkAISLQSPPCNTPQPRPPP 589
Cdd:pfam09770 266 LQRPQSPQPDPAQPSIQPQAQQFHQQPPPVPVQPTQILQNPNRLSAARVGYPQNPQPGVQP-APAHQAHRQQGSFGRQAP 344
|
....*
gi 42569409 590 LISNH 594
Cdd:pfam09770 345 IITHP 349
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
311-537 |
1.67e-03 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 41.79 E-value: 1.67e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 311 NSTAPPRPSVTAAEPMNSAAPPRPSVTAAEPMNSTAPPRPSVTAAEATPPNLSAPLPHCNTPQPSPISQQAAVEsntqmQ 390
Cdd:PRK12323 369 GGGAGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASAR-----G 443
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 391 STALPRPSVTAEARPLHQPHSNTSQPRPIPQQAlaqsntnitsTALPRPSITAEARllhqphsnTPQPRPIPQKALVQAn 470
Cdd:PRK12323 444 PGGAPAPAPAPAAAPAAAARPAAAGPRPVAAAA----------AAAPARAAPAAAP--------APADDDPPPWEELPP- 504
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 42569409 471 tdinSTALPRPLVTAEAPPlhqSSCKAPQPKPISQQPAVQSKTDIINSTALPRPSVTTEARPLHQPR 537
Cdd:PRK12323 505 ----EFASPAPAQPDAAPA---GWVAESIPDPATADPDDAFETLAPAPAAAPAPRAAAATEPVVAPR 564
|
|
| GREB1 |
pfam15782 |
GREB1 N-terminal region; GREB1 (gene regulated by estrogen in breast cancer 1) was first ... |
273-385 |
1.95e-03 |
|
GREB1 N-terminal region; GREB1 (gene regulated by estrogen in breast cancer 1) was first identified as an oestrogen-regulated gene expressed in breast cancer. Its exact function is not known but its expression is regulated by the coordinated binding of oestrogen-receptors to distal sites interacting with Pol II to activate gene transcription from core promoters located at a considerable distance from the greb1 gene.
Pssm-ID: 464866 Cd Length: 1102 Bit Score: 41.69 E-value: 1.95e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 273 KSTCPVKSAATDTATVRAPRSSQHSTQQ-----QQAVQTNRHMNSTAPPRPSVTAaePMNSAAPPR------------PS 335
Cdd:pfam15782 240 GSSEPYPTPASQLDSGHEPQTAAVSHQVsngnqSPPSSTLAKLNPSAPPRPSVLG--THSNSGPPKkrhkgwspessvPD 317
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 42569409 336 VTAAEPMNSTAPPRPSVTAaeATPPNLSAPLPHCNTPQPSPISQQAAVES 385
Cdd:pfam15782 318 STLKVPVPSSRPSTSVSSV--LTNGSPQSCLTQVLPPGPASAPLVPPGES 365
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
310-636 |
2.67e-03 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 40.92 E-value: 2.67e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 310 MNSTAPPRPSVTAAEPMNSAAPPRPSVTAAEPMNSTAPPRPSVTAAEATPPNLSAPLPHCNTPQPSPISQQAAVESNTQM 389
Cdd:PHA03307 60 AACDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTLAPASPAREGSPTPPGPSSPDPPPPTPPPASPPPSPAPDLSEMLR 139
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 390 QSTALPRPSVTAEARPLHQPHSNTSQPRPIPQQALAQSNTNITSTALPRPSITAEARLLHQPHSNTPQPR--PIPQKALV 467
Cdd:PHA03307 140 PVGSPGPPPAASPPAAGASPAAVASDAASSRQAALPLSSPEETARAPSSPPAEPPPSTPPAAASPRPPRRssPISASASS 219
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 468 QANTDINSTALPRPLVTAEAPPLHQSSCK------APQPKPISQQPAVQSKTDIINSTALPRPSVTTEARPLhQPRSKTP 541
Cdd:PHA03307 220 PAPAPGRSAADDAGASSSDSSSSESSGCGwgpeneCPLPRPAPITLPTRIWEASGWNGPSSRPGPASSSSSP-RERSPSP 298
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 542 QPKPVSQPPAKQSNTEINSTPHPRPSVTSKAISLQSPPCNTPQPRPPPLISNHTPTSYQPASAPPvhgiARRTMAPHLRS 621
Cdd:PHA03307 299 SPSSPGSGPAPSSPRASSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPSRSPSPSRPPPPADPS----SPRKRPRPSRA 374
|
330
....*....|....*
gi 42569409 622 SRAPNSAAAPSTYPR 636
Cdd:PHA03307 375 PSSPAASAGRPTRRR 389
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
314-427 |
3.25e-03 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 40.47 E-value: 3.25e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 314 APPRPSVTAAEPMNSAAPPRPSVTAAEPmnstAPPRPSVTAAEATPPNLSAPLPHCNTPQPSPISQQAAVESNTQMQSTA 393
Cdd:PRK14951 376 AEKKTPARPEAAAPAAAPVAQAAAAPAP----AAAPAAAASAPAAPPAAAPPAPVAAPAAAAPAAAPAAAPAAVALAPAP 451
|
90 100 110
....*....|....*....|....*....|....*
gi 42569409 394 LPRPSVTAEARPLH-QPHSNTSQPRPIPQQALAQS 427
Cdd:PRK14951 452 PAQAAPETVAIPVRvAPEPAVASAAPAPAAAPAAA 486
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
314-462 |
5.52e-03 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 39.97 E-value: 5.52e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 314 APPRPSVTAAEPMNSAAPPRPSVTAAEPMNSTAPPRPSVTAAEATPPNLSAPlphcntPQPSPISQQAAVESNTQMQSTA 393
Cdd:PRK07764 616 AAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGD------GWPAKAGGAAPAAPPPAPAPAA 689
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 42569409 394 LPRPSVTAEARPLHQPhsnTSQPRPIPQQALAQSNTNITSTALPRPSITAEARLLHQPHSNTPQPRPIP 462
Cdd:PRK07764 690 PAAPAGAAPAQPAPAP---AATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPPEPDDPPDPAGAP 755
|
|
| dnaA |
PRK14086 |
chromosomal replication initiator protein DnaA; |
431-605 |
7.28e-03 |
|
chromosomal replication initiator protein DnaA;
Pssm-ID: 237605 [Multi-domain] Cd Length: 617 Bit Score: 39.42 E-value: 7.28e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 431 ITSTALPRPSITAEARLLHQPHSNTPQPRPIPqkALVQANTDINSTALPRPLVTAEAPPLHQSSCKAPQPKPI------- 503
Cdd:PRK14086 88 VDPSAGEPAPPPPHARRTSEPELPRPGRRPYE--GYGGPRADDRPPGLPRQDQLPTARPAYPAYQQRPEPGAWpraaddy 165
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 504 --SQQPAVQSKTDIINSTALPRPSVTTEARPLHQPRSKTPQPKP---VSQPPAKQSNTEINSTPHPRPSVTSKAISLQSP 578
Cdd:PRK14086 166 gwQQQRLGFPPRAPYASPASYAPEQERDREPYDAGRPEYDQRRRdydHPRPDWDRPRRDRTDRPEPPPGAGHVHRGGPGP 245
|
170 180
....*....|....*....|....*..
gi 42569409 579 PCNTPQPRPPPLISNHTPTSYQPASAP 605
Cdd:PRK14086 246 PERDDAPVVPIRPSAPGPLAAQPAPAP 272
|
|
| PRK12727 |
PRK12727 |
flagellar biosynthesis protein FlhF; |
463-638 |
7.28e-03 |
|
flagellar biosynthesis protein FlhF;
Pssm-ID: 237182 [Multi-domain] Cd Length: 559 Bit Score: 39.59 E-value: 7.28e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 463 QKALVQANTDINSTAL---PRPLVTAEAPPLHQSSCKAPQPKPISQQPAVQSKTD-IINSTALPRPSVTTEARPLHQPRS 538
Cdd:PRK12727 52 QRALETARSDTPATAAapaPAPQAPTKPAAPVHAPLKLSANANMSQRQRVASAAEdMIAAMALRQPVSVPRQAPAAAPVR 131
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 539 KTPQPKPVSQPPA-KQSNTEINSTPHPRPSVTSK--AISLQSPPCNTPqPRPPPLISNHTPTSYQPASAPPVHGIARRTM 615
Cdd:PRK12727 132 AASIPSPAAQALAhAAAVRTAPRQEHALSAVPEQlfADFLTTAPVPRA-PVQAPVVAAPAPVPAIAAALAAHAAYAQDDD 210
|
170 180
....*....|....*....|....*..
gi 42569409 616 A----PHLRSSRAPNSAAAPSTYPRLA 638
Cdd:PRK12727 211 EqlddDGFDLDDALPQILPPAALPPIV 237
|
|
| PTZ00449 |
PTZ00449 |
104 kDa microneme/rhoptry antigen; Provisional |
316-562 |
9.27e-03 |
|
104 kDa microneme/rhoptry antigen; Provisional
Pssm-ID: 185628 [Multi-domain] Cd Length: 943 Bit Score: 39.29 E-value: 9.27e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 316 PRPSVTAAEPMNSAAPPRPsVTAAEPMNSTAPPRPSVTAAEATPPNLSAPlphcnTPQPSPISQQAAVeSNTQMQSTALP 395
Cdd:PTZ00449 582 PKDPKHPKDPEEPKKPKRP-RSAQRPTRPKSPKLPELLDIPKSPKRPESP-----KSPKRPPPPQRPS-SPERPEGPKII 654
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 396 R-PSVTAEARPLHQPHSNTSQPRPIPQQALAQSNTNITSTALPRPSITAEARLLHQPHSNTPQPRPIPQKalvqantdin 474
Cdd:PTZ00449 655 KsPKPPKSPKPPFDPKFKEKFYDDYLDAAAKSKETKTTVVLDESFESILKETLPETPGTPFTTPRPLPPK---------- 724
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42569409 475 staLPRPLVTAEAPPlhqSSCKAPQPKPISQQPAVQSKTDIINSTA--LPRPSVTTEARPLHQPRSKTPQP-KPVSQP-- 549
Cdd:PTZ00449 725 ---LPRDEEFPFEPI---GDPDAEQPDDIEFFTPPEEERTFFHETPadTPLPDILAEEFKEEDIHAETGEPdEAMKRPds 798
|
250
....*....|...
gi 42569409 550 PAKQSNTEINSTP 562
Cdd:PTZ00449 799 PSEHEDKPPGDHP 811
|
|
| |
