|
Name |
Accession |
Description |
Interval |
E-value |
| PLN02885 |
PLN02885 |
nicotinate phosphoribosyltransferase |
14-557 |
0e+00 |
|
nicotinate phosphoribosyltransferase
Pssm-ID: 178473 [Multi-domain] Cd Length: 545 Bit Score: 1200.25 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 14 IIDGPTNPMVTPLLNDLYQFTMAYAYWKAGKHNERSVFDLYFRKNPFGGEYTVFAGLEECVKFLANFKLTDEEIDFVQEC 93
Cdd:PLN02885 1 VIPRPTNPMVTPLLTDLYQFTMAYAYWKAGKHLDRAVFDLFFRKNPFGGEYTVFAGLEECLRFIANFKFTDDDIDFLRSV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 94 LP-GSEEAFCDYLRGLDCSDVEVYAIPEGSVVFPKVPLMRVEGPVGVVQLLETPFLNLVNFASLVATNAARHRFVAGKSK 172
Cdd:PLN02885 81 MPsGCEDAFFDYLRGLDCSDVEVYAIPEGSVVFPRVPLMRIEGPLAVVQLLETTFLTLVNYASLVATNAARHRLVAGKSK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 173 SLLEFGARRAQGPDGAISASKYCYLGGFDATSNVAAGKLFGIPLRGTHSHAYVSSFMSTDEIVDKVLRSADGKTTCEDFV 252
Cdd:PLN02885 161 VLLEFGLRRAQGPDGGISASKYCYLGGFDATSNVEAGRLFGIPVRGTHSHAFVSSYMGLDEIVDKTLRSADGSSVCEDFV 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 253 SHVQTWLKKIQYSPSLSGIFSETNQSELAAFTSYALAFPKTFLALVDTYDVMKSGIPNFCAVALALNDFGYKALGIRLDS 332
Cdd:PLN02885 241 SLVQEWLSKLQESSSLRGVFSETNQSELAAFTSYALAFPNSFLALVDTYDVMKSGIPNFCAVALALNDLGYKAVGIRLDS 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 333 GDLAYLSREARNFFCTVERELKVPGFGKMVVTASNDLNEETIDALNKQGHEVDAFGIGTYLVTCYSQAALGCVFKLVEIN 412
Cdd:PLN02885 321 GDLAYLSLEARKFFRTIEEELGVPGFGKMSITASNDINEETLDALNKQGHEIDAFGIGTHLVTCYAQPALGCVYKLVEIN 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 413 NQPRIKLSEDVTKVSIPCKKRSYRLYGKEGYPLVDIMTGENEPPPKVGERLLCRHPFNESKRAYVVPQRVEELLKCYWRG 492
Cdd:PLN02885 401 GQPRIKLSEDVEKVTIPCKKRCYRLYGKEGYPLVDLMTGENEPPPKVGERILCRHPFNESKRAYVVPQRVEELLKCYWDG 480
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 30682074 493 SADEAREVLPPLKEIRDRCIKQLENMRPDHMRRLNPTPYKVSVSAKLYDFIHFLWLNEAPVGELQ 557
Cdd:PLN02885 481 SSGKPREELPSLKEIRERCMKQLERMRPDHMRRLNPTPYKVSVSAKLYDFIHFLWLNEAPVGELQ 545
|
|
| NAPRTase_A |
cd01570 |
Nicotinate phosphoribosyltransferase (NAPRTase), subgroup A. Nicotinate ... |
25-409 |
0e+00 |
|
Nicotinate phosphoribosyltransferase (NAPRTase), subgroup A. Nicotinate phosphoribosyltransferase catalyses the formation of NAMN and PPi from 5-phosphoribosy -1-pyrophosphate (PRPP) and nicotinic acid, this is the first, and also rate limiting, reaction in the NAD salvage synthesis. This salvage pathway serves to recycle NAD degradation products. This subgroup is present in bacteria and eukaryota (except funghi).
Pssm-ID: 238804 [Multi-domain] Cd Length: 327 Bit Score: 548.33 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 25 PLLNDLYQFTMAYAYWKAGKHNERSVFDLYFRKNPFGGEYTVFAGLEECVKFLANFKLTDEEIDFVQECLPGSEEaFCDY 104
Cdd:cd01570 1 ALLTDLYQLTMAQAYWKEGKHNKPAVFELFFRKLPFGGGYAVFAGLEELLEYLENFRFTEEDIDYLRSLGIFDEE-FLDY 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 105 LRGLDcSDVEVYAIPEGSVVFPKVPLMRVEGPVGVVQLLETPFLNLVNFASLVATNAARHRFVAGKsKSLLEFGARRAQG 184
Cdd:cd01570 80 LRGFR-FTGTIYAIPEGEVVFPNEPLLTVEGPLIEAQLLETLLLNLINFQTLIATKAARVRLAAGG-RPLLEFGLRRAQG 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 185 PDGAISASKYCYLGGFDATSNVAAGKLFGIPLRGTHSHAYVSSFMstdeivdkvlrsadgkttcedfvshvqtwlkkiqy 264
Cdd:cd01570 158 PDAALSAARAAYIGGFDGTSNVLAGKLYGIPVSGTMAHSFVQAFD----------------------------------- 202
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 265 spslsgifsetnqSELAAFTSYALAFPKTFLALVDTYDVMKSGIPNFCAVALALNDFGYKALGIRLDSGDLAYLSREARN 344
Cdd:cd01570 203 -------------DELAAFRAFAEAYPDNFTLLVDTYDTLRSGLPNAIAVAKELGALGYRLVGVRIDSGDLAYLSKEARK 269
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 30682074 345 FFCTVerelkvpGFGKMVVTASNDLNEETIDALNKQGHEVDAFGIGTYLVTCYSQAALGCVFKLV 409
Cdd:cd01570 270 MLDEA-------GLTKVKIVASNDLDEYTIAALNAQGAPIDAFGVGTRLVTSQSQPALGGVYKLV 327
|
|
| NAPRTase_put |
TIGR01513 |
putative nicotinate phosphoribosyltransferase; A deep split separates two related families of ... |
25-539 |
3.19e-164 |
|
putative nicotinate phosphoribosyltransferase; A deep split separates two related families of proteins, one of which includes experimentally characterized examples of nicotinate phosphoribosyltransferase, an the first enzyme of NAD salvage biosynthesis. This model represents the other family. Members have a different (longer) spacing of several key motifs and have an additional C-terminal domain of up to 100 residues. One argument suggesting that this family represents the same enzyme is that no species has a member of both families. Another is that the gene encoding this protein is located near other NAD salvage biosynthesis genes in Nostoc and in at least four different Gram-positive bacteria. NAD and NADP are ubiquitous in life. Most members of this family are Gram-positive bacteria. An additional set of mutually closely related archaeal sequences score between the trusted and noise cutoffs. [Biosynthesis of cofactors, prosthetic groups, and carriers, Pyridine nucleotides]
Pssm-ID: 273666 [Multi-domain] Cd Length: 443 Bit Score: 474.16 E-value: 3.19e-164
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 25 PLLNDLYQFTMAYAYWKAGKHNERSVFDLYFRKNPFGGEYTVFAGLEECVKFLANFKLTDEEIDFVqECLPGSEEAFCDY 104
Cdd:TIGR01513 1 ALLTDLYELTMAQGYFREGKANQPAVFEVFFRKLPFGRGYAVFAGLEDLLEFLENFRFDAEDIEYL-ASLGIFDDAFLDY 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 105 LRGLDCSdVEVYAIPEGSVVFPKVPLMRVEGPVGVVQLLETPFLNLVNFASLVATNAARHRFVAGKSKsLLEFGARRAQG 184
Cdd:TIGR01513 80 LREFRFS-GTVRALPEGSLVFPNEPLLQVEGPLIEAQLLETLVLNIINFQTLIATKAARIVLAAGGKP-LLEFGLRRAQG 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 185 PDGAISASKYCYLGGFDATSNVAAGKLFGIPLRGTHSHAYVSSFmstdeivdkvlrsadgkttcedfvshvqtwlkkiqy 264
Cdd:TIGR01513 158 PDAALKAARAAYIGGADGTSNVLAGRLYGIPVSGTMAHSFVMSF------------------------------------ 201
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 265 spslsgifsetnQSELAAFTSYALAFPKTFLALVDTYDVMKSGIPNFCAVALALNDFGYkALGIRLDSGDLAYLSREARn 344
Cdd:TIGR01513 202 ------------DNELAAFRAYAKLYPKATVLLVDTYDTLRSGLPNAIAVAKELGEQGK-VVGVRIDSGDLLYLSKQAR- 267
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 345 ffctveRELKVPGFGKMVVTASNDLNEETIDALNKQGHEVDAFGIGTYLVTCYSQAALGCVFKLVEINNQPRIKLSEDVT 424
Cdd:TIGR01513 268 ------KQLDAAGLTQVKIVVSNDLDENSIAALKAEGAPIDVYGVGTSLVTASDAPALGGVYKLVAYEGRPVMKLSENPE 341
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 425 KVSIPCKKRSYRLYGKEGYPLVDIMTGENEPppkvgerllcrHPFNESKRAYVVPQRVEELLK-CYWRGSADEArevLPP 503
Cdd:TIGR01513 342 KSTLPGRKQVFRLYDATGKFLGDELTLADEP-----------IEDLNQEKCTPVFAPVEPLLRlVMKNGQRVRP---LPS 407
|
490 500 510
....*....|....*....|....*....|....*.
gi 30682074 504 LKEIRDRCIKQLENMRPDHMRRLNPTPYKVSVSAKL 539
Cdd:TIGR01513 408 LAEIRARAREQLSKLPPEYLRLLNPHVYPVSLSPRL 443
|
|
| PncB |
COG1488 |
Nicotinic acid phosphoribosyltransferase [Coenzyme transport and metabolism]; Nicotinic acid ... |
21-541 |
4.28e-152 |
|
Nicotinic acid phosphoribosyltransferase [Coenzyme transport and metabolism]; Nicotinic acid phosphoribosyltransferase is part of the Pathway/BioSystem: NAD biosynthesis
Pssm-ID: 441097 [Multi-domain] Cd Length: 445 Bit Score: 443.43 E-value: 4.28e-152
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 21 PMVTPLLNDLYQFTMAYAYWKAGKHNERSVFDLYFRKNPFGGEYTVFAGLEECVKFLANFKLTDEEIDFVQEcLPGSEEA 100
Cdd:COG1488 1 MDNLALLTDLYKLTMAQAYLPEGTANRRAVFELFFRRLPFGRGYVVFAGLQRFLKYLENLRFTEEDIAYLRS-LGVFDED 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 101 FCDYLR--GLDCsdvEVYAIPEGSVVFPKVPLMRVEGPVGVVQLLETPFLNLVNFASLVATNAARHRFVAGkSKSLLEFG 178
Cdd:COG1488 80 FLDYLAdfRFPG---DIRAVPEGTVVFPGEPLLTVEGTLPEAQLLETLLLNILNYPTLIATKAARIVQAAG-GRPLHDFG 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 179 ARRAQGPDGAISASKYCYLGGFDATSNVAAGKLFGIPLRGTHSHAYVSSFmstdeivdkvlrsadgkttcedfvshvqtw 258
Cdd:COG1488 156 LRRAHGLEAAVAAARAAYLAGFAGTSNVLAGRYYGIPSVGTMAHSFVQAH------------------------------ 205
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 259 lkkiqyspslsgifsetnQSELAAFTSYALAFPKTFLALVDTYDVmKSGIPNfcAVALA--LNDFGyKALGIRLDSGDLA 336
Cdd:COG1488 206 ------------------DDELEAFRAFAEAYPDGTTLLVDTYDT-LSGVPN--AIELAkeLLARG-GLLGIRLDSGDLA 263
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 337 YLSREARnffctveRELKVPGFGKMVVTASNDLNEETIDALNKQGHEVDAFGIGTYLVTCYSQAALGCVFKLVEINN--- 413
Cdd:COG1488 264 YLSKQAR-------ELLDEAGLPDVRIIASDDLDEYRIAALLEQGAPIDVFGVGTRLVTSSDRPTLGFVYKLVAVEGdge 336
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 414 -QPRIKLSEDVTKVSIPCKKRSYRlYGKEGYPLVDIMTGENEPPPKVGERLLcrhpfnesKRAYVVPQRVEEllkcywrg 492
Cdd:COG1488 337 wRPVIKLSETPGKKSKPGRKQVYR-RDEDGKATADLVALEDEPLPGEPEPLL--------VPVFRDGKLVYE-------- 399
|
490 500 510 520
....*....|....*....|....*....|....*....|....*....
gi 30682074 493 sadearevLPPLKEIRDRCIKQLENMRPDHMRRLNPTPYKVSVSAKLYD 541
Cdd:COG1488 400 --------LPSLEEIRERAAAQLAELPEELKRLRNPPAYPVDLSEALWD 440
|
|
| NAPRTase_N |
pfam17767 |
Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain; Nicotinate ... |
26-152 |
1.61e-52 |
|
Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain; Nicotinate phosphoribosyltransferase (EC:2.4.2.11) is the rate limiting enzyme that catalyzes the first reaction in the NAD salvage synthesis. This is the N-terminal domain of the enzyme.
Pssm-ID: 465494 [Multi-domain] Cd Length: 125 Bit Score: 175.01 E-value: 1.61e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 26 LLNDLYQFTMAYAYWKAGKhNERSVFDLYFRKNPFGGEYTVFAGLEECVKFLANFKLTDEEIDFVQECLPGSEEAFCDYL 105
Cdd:pfam17767 1 LDTDLYKLTMAQAYFKNGP-DVQVVFEFFNRTNPFGGLYAVFAGLEEQIEFLENLRFTEEEIEYLRRSLPYFKPDFLDYL 79
|
90 100 110 120
....*....|....*....|....*....|....*....|....*..
gi 30682074 106 RGLDCSDVEVyAIPEGSVVFPKVPLMRVEGPVGVVQLLETPFLNLVN 152
Cdd:pfam17767 80 RNFRFDPSIV-AVPEGEVVFPGEPLLRIEGPWLETILLETPLLAIVN 125
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PLN02885 |
PLN02885 |
nicotinate phosphoribosyltransferase |
14-557 |
0e+00 |
|
nicotinate phosphoribosyltransferase
Pssm-ID: 178473 [Multi-domain] Cd Length: 545 Bit Score: 1200.25 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 14 IIDGPTNPMVTPLLNDLYQFTMAYAYWKAGKHNERSVFDLYFRKNPFGGEYTVFAGLEECVKFLANFKLTDEEIDFVQEC 93
Cdd:PLN02885 1 VIPRPTNPMVTPLLTDLYQFTMAYAYWKAGKHLDRAVFDLFFRKNPFGGEYTVFAGLEECLRFIANFKFTDDDIDFLRSV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 94 LP-GSEEAFCDYLRGLDCSDVEVYAIPEGSVVFPKVPLMRVEGPVGVVQLLETPFLNLVNFASLVATNAARHRFVAGKSK 172
Cdd:PLN02885 81 MPsGCEDAFFDYLRGLDCSDVEVYAIPEGSVVFPRVPLMRIEGPLAVVQLLETTFLTLVNYASLVATNAARHRLVAGKSK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 173 SLLEFGARRAQGPDGAISASKYCYLGGFDATSNVAAGKLFGIPLRGTHSHAYVSSFMSTDEIVDKVLRSADGKTTCEDFV 252
Cdd:PLN02885 161 VLLEFGLRRAQGPDGGISASKYCYLGGFDATSNVEAGRLFGIPVRGTHSHAFVSSYMGLDEIVDKTLRSADGSSVCEDFV 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 253 SHVQTWLKKIQYSPSLSGIFSETNQSELAAFTSYALAFPKTFLALVDTYDVMKSGIPNFCAVALALNDFGYKALGIRLDS 332
Cdd:PLN02885 241 SLVQEWLSKLQESSSLRGVFSETNQSELAAFTSYALAFPNSFLALVDTYDVMKSGIPNFCAVALALNDLGYKAVGIRLDS 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 333 GDLAYLSREARNFFCTVERELKVPGFGKMVVTASNDLNEETIDALNKQGHEVDAFGIGTYLVTCYSQAALGCVFKLVEIN 412
Cdd:PLN02885 321 GDLAYLSLEARKFFRTIEEELGVPGFGKMSITASNDINEETLDALNKQGHEIDAFGIGTHLVTCYAQPALGCVYKLVEIN 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 413 NQPRIKLSEDVTKVSIPCKKRSYRLYGKEGYPLVDIMTGENEPPPKVGERLLCRHPFNESKRAYVVPQRVEELLKCYWRG 492
Cdd:PLN02885 401 GQPRIKLSEDVEKVTIPCKKRCYRLYGKEGYPLVDLMTGENEPPPKVGERILCRHPFNESKRAYVVPQRVEELLKCYWDG 480
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 30682074 493 SADEAREVLPPLKEIRDRCIKQLENMRPDHMRRLNPTPYKVSVSAKLYDFIHFLWLNEAPVGELQ 557
Cdd:PLN02885 481 SSGKPREELPSLKEIRERCMKQLERMRPDHMRRLNPTPYKVSVSAKLYDFIHFLWLNEAPVGELQ 545
|
|
| NAPRTase_A |
cd01570 |
Nicotinate phosphoribosyltransferase (NAPRTase), subgroup A. Nicotinate ... |
25-409 |
0e+00 |
|
Nicotinate phosphoribosyltransferase (NAPRTase), subgroup A. Nicotinate phosphoribosyltransferase catalyses the formation of NAMN and PPi from 5-phosphoribosy -1-pyrophosphate (PRPP) and nicotinic acid, this is the first, and also rate limiting, reaction in the NAD salvage synthesis. This salvage pathway serves to recycle NAD degradation products. This subgroup is present in bacteria and eukaryota (except funghi).
Pssm-ID: 238804 [Multi-domain] Cd Length: 327 Bit Score: 548.33 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 25 PLLNDLYQFTMAYAYWKAGKHNERSVFDLYFRKNPFGGEYTVFAGLEECVKFLANFKLTDEEIDFVQECLPGSEEaFCDY 104
Cdd:cd01570 1 ALLTDLYQLTMAQAYWKEGKHNKPAVFELFFRKLPFGGGYAVFAGLEELLEYLENFRFTEEDIDYLRSLGIFDEE-FLDY 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 105 LRGLDcSDVEVYAIPEGSVVFPKVPLMRVEGPVGVVQLLETPFLNLVNFASLVATNAARHRFVAGKsKSLLEFGARRAQG 184
Cdd:cd01570 80 LRGFR-FTGTIYAIPEGEVVFPNEPLLTVEGPLIEAQLLETLLLNLINFQTLIATKAARVRLAAGG-RPLLEFGLRRAQG 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 185 PDGAISASKYCYLGGFDATSNVAAGKLFGIPLRGTHSHAYVSSFMstdeivdkvlrsadgkttcedfvshvqtwlkkiqy 264
Cdd:cd01570 158 PDAALSAARAAYIGGFDGTSNVLAGKLYGIPVSGTMAHSFVQAFD----------------------------------- 202
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 265 spslsgifsetnqSELAAFTSYALAFPKTFLALVDTYDVMKSGIPNFCAVALALNDFGYKALGIRLDSGDLAYLSREARN 344
Cdd:cd01570 203 -------------DELAAFRAFAEAYPDNFTLLVDTYDTLRSGLPNAIAVAKELGALGYRLVGVRIDSGDLAYLSKEARK 269
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 30682074 345 FFCTVerelkvpGFGKMVVTASNDLNEETIDALNKQGHEVDAFGIGTYLVTCYSQAALGCVFKLV 409
Cdd:cd01570 270 MLDEA-------GLTKVKIVASNDLDEYTIAALNAQGAPIDAFGVGTRLVTSQSQPALGGVYKLV 327
|
|
| PRK09243 |
PRK09243 |
nicotinate phosphoribosyltransferase; Validated |
19-539 |
5.08e-177 |
|
nicotinate phosphoribosyltransferase; Validated
Pssm-ID: 236426 [Multi-domain] Cd Length: 464 Bit Score: 507.39 E-value: 5.08e-177
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 19 TNPMVTPLLNDLYQFTMAYAYWKAGKHNERSVFDLYFRKNPFGGEYTVFAGLEECVKFLANFKLTDEEIDFVQEcLPGSE 98
Cdd:PRK09243 4 YNDDSLALLTDLYELTMAQAYLRDGIHNRRAVFELFFRKLPFGRGYAVFAGLERLLEYLENLRFTEEDIEYLRS-LGIFD 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 99 EAFCDYLRGLD--CSdveVYAIPEGSVVFPKVPLMRVEGPVGVVQLLETPFLNLVNFASLVATNAARHRFVAGKsKSLLE 176
Cdd:PRK09243 83 EDFLDYLRNFRftGD---VRAVPEGELVFPNEPLLRVEGPLAEAQLLETLLLNIINFQTLIATKAARIVSAAGG-RPLLE 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 177 FGARRAQGPDGAISASKYCYLGGFDATSNVAAGKLFGIPLRGTHSHAYVSSFMstdeivdkvlrsadgkttcedfvshvq 256
Cdd:PRK09243 159 FGSRRAQGPDAAVWAARAAYIGGFDATSNVLAGKRYGIPVSGTMAHSFVQAFD--------------------------- 211
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 257 twlkkiqyspslsgifsetnqSELAAFTSYALAFPKTFLALVDTYDVMKSGIPNFCAVALALNDfGYKALGIRLDSGDLA 336
Cdd:PRK09243 212 ---------------------DEYEAFRAYAETYPDNTVLLVDTYDTLKSGVPNAIKVAKELGD-GIELGGVRIDSGDLA 269
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 337 YLSREARnffctveRELKVPGFGKMVVTASNDLNEETIDALNKQGHEVDAFGIGTYLVTCYSQAALGCVFKLVEINN--- 413
Cdd:PRK09243 270 YLSKKVR-------KMLDEAGFTDTKIVASNDLDEYTIASLKLQGAPIDGFGVGTKLVTGSDAPALGGVYKLVAIEGegg 342
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 414 -QPRIKLSEDVTKVSIPCKKRSYRLYGKEGYPLVDIMTGENEPPpkvGERLLCRHPFNESKRAYVVPQRVEELLKCYWRG 492
Cdd:PRK09243 343 mIPKIKLSNSPEKVTTPGRKQVYRIYDKGGKAEADVITLADEEE---EEPLKMFHPVHTYKSKTVKNFDAEPLLVPVMEN 419
|
490 500 510 520
....*....|....*....|....*....|....*....|....*..
gi 30682074 493 SadEAREVLPPLKEIRDRCIKQLENMRPDHMRRLNPTPYKVSVSAKL 539
Cdd:PRK09243 420 G--KRVYELPSLEEIRAYAAAQLASLPEEYKRLLNPHAYPVDLSQAL 464
|
|
| NAPRTase_put |
TIGR01513 |
putative nicotinate phosphoribosyltransferase; A deep split separates two related families of ... |
25-539 |
3.19e-164 |
|
putative nicotinate phosphoribosyltransferase; A deep split separates two related families of proteins, one of which includes experimentally characterized examples of nicotinate phosphoribosyltransferase, an the first enzyme of NAD salvage biosynthesis. This model represents the other family. Members have a different (longer) spacing of several key motifs and have an additional C-terminal domain of up to 100 residues. One argument suggesting that this family represents the same enzyme is that no species has a member of both families. Another is that the gene encoding this protein is located near other NAD salvage biosynthesis genes in Nostoc and in at least four different Gram-positive bacteria. NAD and NADP are ubiquitous in life. Most members of this family are Gram-positive bacteria. An additional set of mutually closely related archaeal sequences score between the trusted and noise cutoffs. [Biosynthesis of cofactors, prosthetic groups, and carriers, Pyridine nucleotides]
Pssm-ID: 273666 [Multi-domain] Cd Length: 443 Bit Score: 474.16 E-value: 3.19e-164
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 25 PLLNDLYQFTMAYAYWKAGKHNERSVFDLYFRKNPFGGEYTVFAGLEECVKFLANFKLTDEEIDFVqECLPGSEEAFCDY 104
Cdd:TIGR01513 1 ALLTDLYELTMAQGYFREGKANQPAVFEVFFRKLPFGRGYAVFAGLEDLLEFLENFRFDAEDIEYL-ASLGIFDDAFLDY 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 105 LRGLDCSdVEVYAIPEGSVVFPKVPLMRVEGPVGVVQLLETPFLNLVNFASLVATNAARHRFVAGKSKsLLEFGARRAQG 184
Cdd:TIGR01513 80 LREFRFS-GTVRALPEGSLVFPNEPLLQVEGPLIEAQLLETLVLNIINFQTLIATKAARIVLAAGGKP-LLEFGLRRAQG 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 185 PDGAISASKYCYLGGFDATSNVAAGKLFGIPLRGTHSHAYVSSFmstdeivdkvlrsadgkttcedfvshvqtwlkkiqy 264
Cdd:TIGR01513 158 PDAALKAARAAYIGGADGTSNVLAGRLYGIPVSGTMAHSFVMSF------------------------------------ 201
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 265 spslsgifsetnQSELAAFTSYALAFPKTFLALVDTYDVMKSGIPNFCAVALALNDFGYkALGIRLDSGDLAYLSREARn 344
Cdd:TIGR01513 202 ------------DNELAAFRAYAKLYPKATVLLVDTYDTLRSGLPNAIAVAKELGEQGK-VVGVRIDSGDLLYLSKQAR- 267
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 345 ffctveRELKVPGFGKMVVTASNDLNEETIDALNKQGHEVDAFGIGTYLVTCYSQAALGCVFKLVEINNQPRIKLSEDVT 424
Cdd:TIGR01513 268 ------KQLDAAGLTQVKIVVSNDLDENSIAALKAEGAPIDVYGVGTSLVTASDAPALGGVYKLVAYEGRPVMKLSENPE 341
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 425 KVSIPCKKRSYRLYGKEGYPLVDIMTGENEPppkvgerllcrHPFNESKRAYVVPQRVEELLK-CYWRGSADEArevLPP 503
Cdd:TIGR01513 342 KSTLPGRKQVFRLYDATGKFLGDELTLADEP-----------IEDLNQEKCTPVFAPVEPLLRlVMKNGQRVRP---LPS 407
|
490 500 510
....*....|....*....|....*....|....*.
gi 30682074 504 LKEIRDRCIKQLENMRPDHMRRLNPTPYKVSVSAKL 539
Cdd:TIGR01513 408 LAEIRARAREQLSKLPPEYLRLLNPHVYPVSLSPRL 443
|
|
| PncB |
COG1488 |
Nicotinic acid phosphoribosyltransferase [Coenzyme transport and metabolism]; Nicotinic acid ... |
21-541 |
4.28e-152 |
|
Nicotinic acid phosphoribosyltransferase [Coenzyme transport and metabolism]; Nicotinic acid phosphoribosyltransferase is part of the Pathway/BioSystem: NAD biosynthesis
Pssm-ID: 441097 [Multi-domain] Cd Length: 445 Bit Score: 443.43 E-value: 4.28e-152
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 21 PMVTPLLNDLYQFTMAYAYWKAGKHNERSVFDLYFRKNPFGGEYTVFAGLEECVKFLANFKLTDEEIDFVQEcLPGSEEA 100
Cdd:COG1488 1 MDNLALLTDLYKLTMAQAYLPEGTANRRAVFELFFRRLPFGRGYVVFAGLQRFLKYLENLRFTEEDIAYLRS-LGVFDED 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 101 FCDYLR--GLDCsdvEVYAIPEGSVVFPKVPLMRVEGPVGVVQLLETPFLNLVNFASLVATNAARHRFVAGkSKSLLEFG 178
Cdd:COG1488 80 FLDYLAdfRFPG---DIRAVPEGTVVFPGEPLLTVEGTLPEAQLLETLLLNILNYPTLIATKAARIVQAAG-GRPLHDFG 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 179 ARRAQGPDGAISASKYCYLGGFDATSNVAAGKLFGIPLRGTHSHAYVSSFmstdeivdkvlrsadgkttcedfvshvqtw 258
Cdd:COG1488 156 LRRAHGLEAAVAAARAAYLAGFAGTSNVLAGRYYGIPSVGTMAHSFVQAH------------------------------ 205
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 259 lkkiqyspslsgifsetnQSELAAFTSYALAFPKTFLALVDTYDVmKSGIPNfcAVALA--LNDFGyKALGIRLDSGDLA 336
Cdd:COG1488 206 ------------------DDELEAFRAFAEAYPDGTTLLVDTYDT-LSGVPN--AIELAkeLLARG-GLLGIRLDSGDLA 263
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 337 YLSREARnffctveRELKVPGFGKMVVTASNDLNEETIDALNKQGHEVDAFGIGTYLVTCYSQAALGCVFKLVEINN--- 413
Cdd:COG1488 264 YLSKQAR-------ELLDEAGLPDVRIIASDDLDEYRIAALLEQGAPIDVFGVGTRLVTSSDRPTLGFVYKLVAVEGdge 336
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 414 -QPRIKLSEDVTKVSIPCKKRSYRlYGKEGYPLVDIMTGENEPPPKVGERLLcrhpfnesKRAYVVPQRVEEllkcywrg 492
Cdd:COG1488 337 wRPVIKLSETPGKKSKPGRKQVYR-RDEDGKATADLVALEDEPLPGEPEPLL--------VPVFRDGKLVYE-------- 399
|
490 500 510 520
....*....|....*....|....*....|....*....|....*....
gi 30682074 493 sadearevLPPLKEIRDRCIKQLENMRPDHMRRLNPTPYKVSVSAKLYD 541
Cdd:COG1488 400 --------LPSLEEIRERAAAQLAELPEELKRLRNPPAYPVDLSEALWD 440
|
|
| NAPRTase_PncB |
cd01567 |
Nicotinate phosphoribosyltransferase (NAPRTase) family. Nicotinate phosphoribosyltransferase ... |
25-407 |
7.84e-116 |
|
Nicotinate phosphoribosyltransferase (NAPRTase) family. Nicotinate phosphoribosyltransferase catalyses the formation of NAMN and PPi from 5-phosphoribosy -1-pyrophosphate (PRPP) and nicotinic acid, this is the first, and also rate limiting, reaction in the NAD salvage synthesis. This salvage pathway serves to recycle NAD degradation products.
Pssm-ID: 238801 [Multi-domain] Cd Length: 343 Bit Score: 346.95 E-value: 7.84e-116
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 25 PLLNDLYQFTMAYAYWKaGKHNERSVFDLYFRKNPFGGEYTVFAGLEECVKFLANFKLTDEEIDFVQECLPGSEeaFCDY 104
Cdd:cd01567 1 LLDTDLYKLTMMQAYLY-PYPNTRVVFEFTFRSNPFGGDYIVFAGLEEVLKLLENLRFTEEEIEYLKKLLIFGE--FFLY 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 105 LRGLDCSDVEVYAIPEGSVVFPKVPLMRVEGPVGVVQLLETPFLNLVNFASLVATNAARHRFVAGKS-----------KS 173
Cdd:cd01567 78 LLFLGKLPLEIYALPEGTVVFPKEPLLTIEGPWPEAGLLETPLLAIWNEATSIATKAARKKLAAGGLletkdnleelgFK 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 174 LLEFGARRAQGPDGAISASKYCYLGGFDATSNVAAGKLFGIPLRGTHSHAYVSSFMSTdeivdkvlrsadgkttcedfvs 253
Cdd:cd01567 158 LHDFGTRRRHSPEAALSGGRAALIGGFGGTSNVAAAKKLGIPPIGTMAHSWIQAFGAL---------------------- 215
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 254 hvqtwlkkiqyspslsgifsetnqsELAAFTSYALAFPKT----FLALVDTYDvMKSGIPNFCAVALALNDfGYKALGIR 329
Cdd:cd01567 216 -------------------------EEAAFEAFARWLPQFggglGIALIDTYD-TDNGFLNALKLAKALGA-GGGLLGVR 268
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 330 LDSGDLAYLSREARNFFCTVERELKvpgfgKMVVTASNDLN-EETIDALNKQGH-EVDAFGIGTYLVTCYSQAALGCVFK 407
Cdd:cd01567 269 LDSGDPVELIKKVRKHLDELGIDLN-----KKKIIISGDLDtEEAIELLLEQGAsPNDAFGVGTSLTNDLGRPPLGFVYK 343
|
|
| PRK12484 |
PRK12484 |
nicotinate phosphoribosyltransferase; Provisional |
22-539 |
4.84e-107 |
|
nicotinate phosphoribosyltransferase; Provisional
Pssm-ID: 237112 [Multi-domain] Cd Length: 443 Bit Score: 327.86 E-value: 4.84e-107
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 22 MVTPLLNDLYQFTMAYAYWKAGKhNERSVFDLYFRKNPFGGEYTVFAGLEECVKFLANFKLTDEEIDFVQECLpGSEEAF 101
Cdd:PRK12484 2 RNLALLTDLYEVTMANAYLREGM-SAPATFSLFYRKLPDGRGFLIAAGLADVVEFLEAFRFDEQDLRYLRGLN-QFSEEF 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 102 CDYLRGLDCSDvEVYAIPEGSVVFPKVPLMRVEGPVGVVQLLETPFLNLVNFASLVATNAARHRFvAGKSKSLLEFGARR 181
Cdd:PRK12484 80 LAWLAGLRFTG-DVRAVPEGTVVFPNEPLLEVTAPLIEAQLVETFLLNQINHQSLIASKAARCVL-AAAGRPVVDFGARR 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 182 AQGPDGAISASKYCYLGGFDATSNVAAGKLFGIPLRGTHSHAYVSSFmstdeivdkvlrsadgkttcedfvshvqtwlkk 261
Cdd:PRK12484 158 AHGTDAACYVARASYLAGAAGTSNVLAARQYGIPASGTMAHSFVEAF--------------------------------- 204
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 262 iqyspslsgifsetnQSELAAFTSYALAFPKTFLALVDTYDVMKsGIPNFCAVALALnDFGYKALGIRLDSGDLAYLSRE 341
Cdd:PRK12484 205 ---------------PDEVAAFRAFARLYPDATTLLVDTYDTLR-GVRNAIEVAKEL-GNRFDPRGVRLDSGDLAELSKA 267
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 342 ARnffctveRELKVPGFGKMVVTASNDLNEETIDALNKQGHEVDAFGIGTYLVTCYSQAALGCVFKLVEINNQPRIKLSE 421
Cdd:PRK12484 268 TR-------AILDAAGLEQVKIVASGGLDEYRIAALLAAGAPIDGFGVGTRLGVAADAPVLDSAYKLVAYEGRGVTKLSS 340
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 422 DvtKVSIPCKKRSYRLYGKEGYpLVDIMTGENEPPPKVGERLLCrhPFNESKRAYVVPqrveellkcywrgsadearevl 501
Cdd:PRK12484 341 G--KVTYPGRKQVFRLYEHGTA-CGDVIGLHTENIPDGREPLLV--PVMTNGRRIQHA---------------------- 393
|
490 500 510
....*....|....*....|....*....|....*....
gi 30682074 502 PPLKEIRDRCIKQLENMrPDHMRRL-NPTPYKVSVSAKL 539
Cdd:PRK12484 394 PTLDGARDWCEAQLAAL-PPEARRLvDPVAVSVTLSGEL 431
|
|
| PRTase_typeII |
cd00516 |
Phosphoribosyltransferase (PRTase) type II; This family contains two enzymes that play an ... |
29-407 |
5.18e-69 |
|
Phosphoribosyltransferase (PRTase) type II; This family contains two enzymes that play an important role in NAD production by either allowing quinolinic acid (QA) , quinolinate phosphoribosyl transferase (QAPRTase), or nicotinic acid (NA), nicotinate phosphoribosyltransferase (NAPRTase), to be used in the synthesis of NAD. QAPRTase catalyses the reaction of quinolinic acid (QA) with 5-phosphoribosyl-1-pyrophosphate (PRPP) in the presence of Mg2+ to produce nicotinic acid mononucleotide (NAMN), pyrophosphate and carbon dioxide, an important step in the de novo synthesis of NAD. NAPRTase catalyses a similar reaction leading to NAMN and pyrophosphate, using nicotinic acid an PPRP as substrates, used in the NAD salvage pathway.
Pssm-ID: 238286 [Multi-domain] Cd Length: 281 Bit Score: 223.66 E-value: 5.18e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 29 DLYQFTMAYAYwkaGKHNERSVFDLYFRKNPFGgeytVFAGLEECVKFLANFKLtdeeidfvqeclpgseeafcdylrgl 108
Cdd:cd00516 1 DLYKLTMIQAY---PPPDTRATAEFTAREDPYG----VLAGLEEALELLELLRF-------------------------- 47
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 109 dCSDVEVYAIPEGSVVFPKVPLMRVEGPVGVVQLLETPFLNLVNFASLVATNAARHRFVA-GKSKSLLEFGARRAQgPDG 187
Cdd:cd00516 48 -PGPLVILAVPEGTVVEPGEPLLTIEGPARELLLLERVLLNLLQRLSGIATATARYVEAAkGANTKVHDFGTRKTT-PGL 125
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 188 AISASKYCYLGGFDATSNVAAGKLFGIPLRGTHSHAYVSSFmstdeivdkvlrsadgkttcedfvshvqtwlkkiqysps 267
Cdd:cd00516 126 RLLEKYAVLIGGGDGHRNGLSDAILIKDNHGTMAHSIIQAF--------------------------------------- 166
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 268 lsgifsetnqSELAAFTSYALAFPKTFLALVDTYDVMksgIPNFCAVALALndfgyKALGIRLDSG-----DLAYLSREA 342
Cdd:cd00516 167 ----------GELAAVKALRRWLPELFIALIDVEVDT---LEEALEAAKAG-----GADGIRLDSGspeelDPAVLILKA 228
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 30682074 343 RnffctveRELKVPGFGKMVVTASNDLNEETIDALNKQGheVDAFGIGTYLVTCysqAALGCVFK 407
Cdd:cd00516 229 R-------AHLDGKGLPRVKIEASGGLDEENIRAYAETG--VDVFGVGTLLHSA---PPLDIVLK 281
|
|
| NAPRTase_N |
pfam17767 |
Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain; Nicotinate ... |
26-152 |
1.61e-52 |
|
Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain; Nicotinate phosphoribosyltransferase (EC:2.4.2.11) is the rate limiting enzyme that catalyzes the first reaction in the NAD salvage synthesis. This is the N-terminal domain of the enzyme.
Pssm-ID: 465494 [Multi-domain] Cd Length: 125 Bit Score: 175.01 E-value: 1.61e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 26 LLNDLYQFTMAYAYWKAGKhNERSVFDLYFRKNPFGGEYTVFAGLEECVKFLANFKLTDEEIDFVQECLPGSEEAFCDYL 105
Cdd:pfam17767 1 LDTDLYKLTMAQAYFKNGP-DVQVVFEFFNRTNPFGGLYAVFAGLEEQIEFLENLRFTEEEIEYLRRSLPYFKPDFLDYL 79
|
90 100 110 120
....*....|....*....|....*....|....*....|....*..
gi 30682074 106 RGLDCSDVEVyAIPEGSVVFPKVPLMRVEGPVGVVQLLETPFLNLVN 152
Cdd:pfam17767 80 RNFRFDPSIV-AVPEGEVVFPGEPLLRIEGPWLETILLETPLLAIVN 125
|
|
| NAPRTase_C |
pfam17956 |
Nicotinate phosphoribosyltransferase C-terminal domain; This domain is found at the C-terminus ... |
431-542 |
8.66e-42 |
|
Nicotinate phosphoribosyltransferase C-terminal domain; This domain is found at the C-terminus of some Nicotinate phosphoribosyltransferase enzymes. The function of this domain is uncertain.
Pssm-ID: 465585 [Multi-domain] Cd Length: 111 Bit Score: 145.79 E-value: 8.66e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 431 KKRSYRLYGKEGYPLVDIMTGENEPPPKVGERLLCRHPFNESKRAYVVPQRVEELLKCYWRGSadEAREVLPPLKEIRDR 510
Cdd:pfam17956 1 RKQVYRLYDKDGKAIADLITLADEPPPDPGEEILCFHPFDEWKRKTVTPFTVEPLLKPVFEDG--KLVYELPTLEEIRAY 78
|
90 100 110
....*....|....*....|....*....|..
gi 30682074 511 CIKQLENMRPDHMRRLNPTPYKVSVSAKLYDF 542
Cdd:pfam17956 79 VQEQLSRLWPEHKRLLNPHPYKVDLSEKLYQL 110
|
|
| NAPRTase_B |
cd01571 |
Nicotinate phosphoribosyltransferase (NAPRTase), subgroup B. Nicotinate ... |
29-418 |
4.40e-36 |
|
Nicotinate phosphoribosyltransferase (NAPRTase), subgroup B. Nicotinate phosphoribosyltransferase catalyses the formation of NAMN and PPi from 5-phosphoribosy -1-pyrophosphate (PRPP) and nicotinic acid, this is the first, and also rate limiting, reaction in the NAD salvage synthesis. This salvage pathway serves to recycle NAD degradation products.
Pssm-ID: 238805 [Multi-domain] Cd Length: 302 Bit Score: 136.63 E-value: 4.40e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 29 DLYqFTMAYAYWKAGKHNERSVFDLYFRKNPFGgeytVFAGLEECVKFLANFKltdeeidfvqeclpgseeafcdylrgl 108
Cdd:cd01571 5 DVY-FLRTRKILEKKGPNPTVTMEFTQRSLPWA----VLCGLEEVLALLEGLP--------------------------- 52
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 109 dcsdVEVYAIPEGSVVFPKVPLMRVEGPVGVVQLLETPFLNLVNFASLVATNAARHRFVAGkSKSLLEFGARR---AQGP 185
Cdd:cd01571 53 ----VKVYALPEGTIFNPKEPVLRIEGPYQDFGELETAILGILARASSIATNAARVKLAAG-DKPVISFGDRRdhpAIQP 127
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 186 DGAISAskycYLGGFDATSNVAAGKLFGIPLRGTHSHAYVSSFMStdeivdkvlrsadgkttcedfvSHVQTWLkkiqys 265
Cdd:cd01571 128 MDGRAA----YIGGCDGVSTVLGAELLGEKPSGTMPHALIQIFGG----------------------DQVEAWK------ 175
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 266 pslsgifsetnqselaaftSYALAFPKT--FLALVDTYDVMKSGipnfcaVALALNDFGYKALGIRLDS-----GDLAYL 338
Cdd:cd01571 176 -------------------AFDETYPEDvpRIALIDTFNDEKEE------ALKAAKALGDKLDGVRLDTpssrrGVFRYL 230
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 339 SREARnffctveRELKVPGFGKMVVTASNDLNEETIDALNKQGheVDAFGIGTYLVtcySQAALGCVFKLVEINNQPRIK 418
Cdd:cd01571 231 IREVR-------WALDIRGYKHVKIFVSGGLDEEDIKELEDVG--VDAFGVGTAIS---KAPPVDFTMDIVEVNGQPIAK 298
|
|
| PRK08662 |
PRK08662 |
nicotinate phosphoribosyltransferase; Reviewed |
61-392 |
8.77e-29 |
|
nicotinate phosphoribosyltransferase; Reviewed
Pssm-ID: 236328 [Multi-domain] Cd Length: 343 Bit Score: 116.90 E-value: 8.77e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 61 GGEYTVFAGLEECVKFLanfkltdeeidfvqeclpgseeafcdylRGLDcsdVEVYAIPEGSVVFPKVPLMRVEGPVGVV 140
Cdd:PRK08662 49 KGEWGVFAGLEEVLELL----------------------------EGKP---VDVYALPEGTLFDPKEPVMRIEGPYLEF 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 141 QLLETPFLNLVNFASLVATNAARHRFVAGkSKSLLEFGARRAQgPDGAISASKYCYLGGFDATSNVAAGKLFGIPLRGTH 220
Cdd:PRK08662 98 GIYETALLGILAHASGIATAAARCKEAAG-DKPVLSFGARHVH-PAIAPMMDRAAYIGGCDGVSGVLGAELLGIEPSGTM 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 221 SHAYVssfmstdeIVdkvlrsadgkttcedFVSHVQTWLkkiqyspslsgIFSETNQSELaaftsyalafPKTflALVDT 300
Cdd:PRK08662 176 PHALI--------LI---------------FGDQVEAWK-----------AFDEVVPPDV----------PRI--ALVDT 209
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 301 YDVMKSgipnfcAVALALNDFGYKALGIRLDS-----GDLAYLSREARnffctveRELKVPGFGKMVVTASNDLNEETID 375
Cdd:PRK08662 210 FKDERE------EALRAAEALGDRLDGVRLDTpssrrGNFRKIVREVR-------WTLDIRGYEHVKIFVSGGLDPERIR 276
|
330
....*....|....*..
gi 30682074 376 ALNKqghEVDAFGIGTY 392
Cdd:PRK08662 277 ELRD---VVDGFGVGTY 290
|
|
| PncB_like |
cd01401 |
Nicotinate phosphoribosyltransferase (NAPRTase), related to PncB. Nicotinate ... |
26-425 |
1.36e-16 |
|
Nicotinate phosphoribosyltransferase (NAPRTase), related to PncB. Nicotinate phosphoribosyltransferase catalyses the formation of NAMN and PPi from 5-phosphoribosy -1-pyrophosphate (PRPP) and nicotinic acid, this is the first, and also rate limiting, reaction in the NAD salvage synthesis. This salvage pathway serves to recycle NAD degradation products. This subgroup is present in bacteria, archea and funghi.
Pssm-ID: 238695 [Multi-domain] Cd Length: 377 Bit Score: 81.52 E-value: 1.36e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 26 LLNDLYQFTMAYAYWKAGKHNErSVFDLYFRkNP--FGGEYtvFAGLEECVKFLANFKLTDEEIDFVQECLPGSEEAFCD 103
Cdd:cd01401 4 LDTDLYKLTMQQAVLHHYPDVQ-VTYEFTNR-SPedFLEEA--AEALREQIDHLANLRFSEEELAYLRRSLPFLKPDYLD 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 104 YLRG--LDCSDVEVYAIPEGSVVFpkvplMRVEGPVGVVQLLETPFLNLVN-----FASLVATNAARHRFVAGKSKSLL- 175
Cdd:cd01401 80 YLELfrLNPEEVVVRLDTGKGQLD-----IRISGPWKDTILYEVPLLAIVSevyfrFRDADWDYEEQLEKLEEKLERLLe 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 176 -------------EFGARRAQGPD-------GAISASKYCYLGgfdaTSNVAAGKLFGIPLRGTHSHAYvssFMSTDEIV 235
Cdd:cd01401 155 eakrrdlngfrfsDFGTRRRFSYEvqetvlkGLKQAAPGYLTG----TSNVHFAMKYGLTPIGTVAHEW---FMAHQALT 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 236 DkVLRSADGKTtcedfvshVQTWLKkiQYSPSLsGIfsetnqselaaftsyalafpktflALVDTYdvmksGIPNFcava 315
Cdd:cd01401 228 G-DLKDSQKAA--------LERWVR--EYGGDL-GI------------------------ALTDTF-----GTDAF---- 262
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 316 laLNDFG-YKA---LGIRLDSGDLAYLSREARNFFctveRELKVPGFGKMVVTaSNDLNEETIDALNK--QGHEVDAFGI 389
Cdd:cd01401 263 --LRDFDlYFAklfDGVRHDSGDPFEWGEKAIAHY----EKLGIDPKTKTLVF-SDGLDVEKALELYEyfKGRIKVSFGI 335
|
410 420 430 440
....*....|....*....|....*....|....*....|
gi 30682074 390 GTYL----VTCYSQAALGCVFKLVEINNQPRIKLSEDVTK 425
Cdd:cd01401 336 GTNLtndfGNKEKSTPLNIVIKLVECNGRPVAKISDSPGK 375
|
|
| PRK05321 |
PRK05321 |
nicotinate phosphoribosyltransferase; Provisional |
20-425 |
3.37e-12 |
|
nicotinate phosphoribosyltransferase; Provisional
Pssm-ID: 235406 [Multi-domain] Cd Length: 400 Bit Score: 68.25 E-value: 3.37e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 20 NPMVTPLL-NDLYQFTMAYAYWkagkHNERSVFDLY-FR---KNPFGGEYtvFAGLEECVKFLANFKLTDEEIDFVQECl 94
Cdd:PRK05321 6 DPIIRSLLdTDFYKLTMQQAVL----HHYPDAQVEYeFIcrnDEVDLAEY--IDEIREQLDHLCTLRLTDDELDYLRGL- 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 95 PGSEEAFCDYLRG--LDCSDVEVyAIPEGSVVfpkvplMRVEGPVGVVQLLETPFLNLVN------FASLVATNAARHR- 165
Cdd:PRK05321 79 PFFKPDFLDWLRLfrLNPYEVTV-SIDDGQLD------IRIEGPWLETILWEVPLLAIISelyfraRSPEVLYAQAKRRl 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 166 ------FVAGKSKSLL---EFGARR-----AQgpDGAISASKYCYLGGFDATSNVAAGKLFGIPLRGTHSHAYvssFMST 231
Cdd:PRK05321 152 wekielLKALPDLSGFkiaDFGTRRrfsfeWQ--EEVVEALKEGLPGAFVGTSNVHLAMKLGLTPIGTMAHEW---FMAH 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 232 DEIVDKvLRSADgKTTCEDfvshvqtWLKkiQYSPSLsGIfsetnqselaaftsyalafpktflALVDTYdvmksGIPNF 311
Cdd:PRK05321 227 QALGPR-LRDSQ-YAALED-------WVR--EYRGDL-GI------------------------ALTDTI-----GMDAF 265
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 312 cavalaLNDFG--YKAL--GIRLDSGD--------LAYLsrearnffctveRELKVPGFGKMVVtASNDLNEETIDALNK 379
Cdd:PRK05321 266 ------LRDFDlyFAKLfdGLRHDSGDpiewgekaIAHY------------EKLGIDPRTKTLV-FSDGLDFDKALELYR 326
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|
gi 30682074 380 QGHE-VD-AFGIGTYLvTC--YSQAALGCVFKLVEINNQPRIKLSEDVTK 425
Cdd:PRK05321 327 HFKGrIKlSFGIGTNL-TNdfPGVKPLNIVIKLVECNGRPVAKLSDSPGK 375
|
|
| NAPRTase |
pfam04095 |
Nicotinate phosphoribosyltransferase (NAPRTase) family; Nicotinate phosphoribosyltransferase ... |
173-425 |
3.95e-07 |
|
Nicotinate phosphoribosyltransferase (NAPRTase) family; Nicotinate phosphoribosyltransferase (EC:2.4.2.11) is the rate limiting enzyme that catalyzes the first reaction in the NAD salvage synthesis. This family also includes Pre-B cell enhancing factor that is a cytokine Swiss:P43490. This family is related to Quinolinate phosphoribosyltransferase pfam01729.
Pssm-ID: 397974 [Multi-domain] Cd Length: 235 Bit Score: 51.23 E-value: 3.95e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 173 SLLEFGARRAQGPDGA-ISASKYcyLGGFDATSNVAAGKLFGIPLRGTHSHayvssfmstdeivdkvlrsadgkttcedf 251
Cdd:pfam04095 2 KLHDFGTRRRSSLESQeIVGLAH--LVNFLGTSNVHFAAKYSIPPAGTSAH----------------------------- 50
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 252 vshvqTWLKKIQyspSLSGIFSetnQSELAAFTSYALAFPKTFL-ALVDTYdVMKSGIPNFCAvalalnDFGYKALGIRL 330
Cdd:pfam04095 51 -----EWWGAHQ---ELDANLR---QFQKDALDLWHAEYRGNLGiALTDTV-TMDAFLKDFDL------YFAKLYLGVRP 112
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 331 DSGD-LAYLSREARNFfctvERELKVPGFGKMVVTaSNDLNEETIDALNKQGHEVD---AFGIGTYLvTC---------- 396
Cdd:pfam04095 113 DSGDpVEWGEKLIAHY----GSTLNIDGYTKRLIF-SDGLDVEKIIELLEYFKGKGfniAFGIGTNL-TQdlnrdtlgfa 186
|
250 260
....*....|....*....|....*....
gi 30682074 397 YSQAALGCVFKLVEINNQPRIKLSEDVTK 425
Cdd:pfam04095 187 VKATPLNIVIKLVEVNGDPVAKISDSSGK 215
|
|
| PRK07188 |
PRK07188 |
nicotinate phosphoribosyltransferase; Provisional |
109-418 |
1.10e-05 |
|
nicotinate phosphoribosyltransferase; Provisional
Pssm-ID: 235953 [Multi-domain] Cd Length: 352 Bit Score: 47.64 E-value: 1.10e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 109 DCSDVEVYAIPEGSVVFPKVPLMRVEGPVGVVQLLETPFLNLVNFASLVATNAarHRFV-AGKSKSLLeFGARRA----- 182
Cdd:PRK07188 68 DPSKLKIRYLKDGDIINPFETVLEIEGPYENFGFLEGIIDGILARRTSVATNA--YNVVqAANEKPVI-FMGDRAdhylq 144
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 183 QGPDGaisasKYCYLGGFDATSNVAAGKLFGIPLRGTHSHAYVSSFmstdeivdkvlrsaDGKTtcedfvshvqtwlkki 262
Cdd:PRK07188 145 QAGDG-----YAAYIGGISAFSTHAQNEWWGKSGFGTMPHALIQMF--------------NGDV---------------- 189
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 263 qyspslsgifsetnqseLAAFTSYALAFP-KTFLALVD-TYDVMKSgipnfcavAL-ALNDFGYKALGIRLD-SGDLA-- 336
Cdd:PRK07188 190 -----------------VEACKAYHKTFPeDELIALVDyNNDVITD--------SLkVAREFGDKLKGVRVDtSKNMIdk 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 337 YLSREARNFFCT------------VERELKVPGFGKMVVTASNDLNEETIDALNKQGHEVDAFGIGTYLVTcysqaaLGC 404
Cdd:PRK07188 245 YFIRHPEVLGTFdprgvnpelikaLRKALDENGGKHVKIIVSSGFDAKKIREFEAQNVPVDIYGVGSSLLK------INI 318
|
330
....*....|....*.
gi 30682074 405 VFK--LVEINNQPRIK 418
Cdd:PRK07188 319 GFTgdAVELNGKKEAK 334
|
|
| nadV |
PHA02594 |
nicotinamide phosphoribosyl transferase; Provisional |
53-232 |
3.69e-05 |
|
nicotinamide phosphoribosyl transferase; Provisional
Pssm-ID: 222898 [Multi-domain] Cd Length: 470 Bit Score: 46.18 E-value: 3.69e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 53 LYFRKNPFGGEYT---VFAGLEECV-KFLANfKLTDEEIDFVQECLPG--SEEAF----CDYLRGLDCSDVEVYAIPEGS 122
Cdd:PHA02594 32 VMFYLEPRGGKFFdkvVVFGIQYFVkKYFFE-PITMEVVEEAHELVKAhlGKDVFnrehWEALHDLGYLPIEVRAVPEGT 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 123 VVFPKVPLMRVE--GP--VGVVQLLETPFLNLVNFASLVATNAARHRfvagksKSLLEFGARRAQGPDGAISASkycylg 198
Cdd:PHA02594 111 VVPVKVPVLTIEntHPdfFWLAGYLETVILRGVWYPSTVATLSRECK------KILKKYLKETSDNEDEVLDFQ------ 178
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 30682074 199 GFDatsnvaagklFGipLRGTHSH--------AYVSSFMSTD 232
Cdd:PHA02594 179 LHD----------FG--ARGMSSGesaalgglAHLYNFKGTD 208
|
|
| PBEF_like |
cd01569 |
pre-B-cell colony-enhancing factor (PBEF)-like. The mammalian members of this group of ... |
113-413 |
1.26e-04 |
|
pre-B-cell colony-enhancing factor (PBEF)-like. The mammalian members of this group of nicotinate phosphoribosyltransferases (NAPRTases) were originally identified as genes whose expression is upregulated upon activation in lymphoid cells. In general, nicotinate phosphoribosyltransferase catalyses the formation of NAMN and PPi from 5-phosphoribosy -1-pyrophosphate (PRPP) and nicotinic acid, this is the first, and also rate limiting, reaction in the NAD salvage synthesis.
Pssm-ID: 238803 [Multi-domain] Cd Length: 407 Bit Score: 44.57 E-value: 1.26e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 113 VEVYAIPEGSVVFPKVPLMRVE--GP--VGVVQLLETPFLNLVNFASLVATNAARHR---------------FVAGKsks 173
Cdd:cd01569 96 IEIRAVPEGTVVPTKNVLMTVEntDPdfFWLTNYLETILLRNVWYPSTVATISREYKkilrkyaketsdnleFLPFQ--- 172
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 174 LLEFGARRAQGPDGAIsaskycyLGGFdatsnvaagklfgiplrgthshAYVSSFMSTDEIvdKVLRSADGKTTCEDFVS 253
Cdd:cd01569 173 LHDFGMRGMSSLESAA-------LGGA----------------------AHLVNFKGTDTI--PALDAAYAYYYEDPMAG 221
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 254 hvqtwlkkiqYS-PSL--SGIFSETNQSELAAFTSYALAFPKTFLALV-DTYD---VMKSGIPNFCAVALALNdfgyKAL 326
Cdd:cd01569 222 ----------FSiPAAehSTMTAWGRERELEAFRNLLEQFGPGIVSVVsDSYDfwnALTLWGPRLKDEILARG----GTL 287
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 327 GIRLDSGD-----LAYLSREARNFFCTV-ERELKV--PGFGkmvVTASNDLNEETIDA----LNKQGHEVD--AFGIGTY 392
Cdd:cd01569 288 VIRPDSGDpvdiiCGVLEILGEIFGGTVnSKGYKVlnPHVR---IIQGDGITLERIEEilerLKAKGFASEniVFGMGGG 364
|
330 340
....*....|....*....|...
gi 30682074 393 LVTCYSQAALGCVFKL--VEINN 413
Cdd:cd01569 365 LLQKVTRDTQGFAMKAsaIEING 387
|
|
| PRK09198 |
PRK09198 |
putative nicotinate phosphoribosyltransferase; Provisional |
61-209 |
4.66e-04 |
|
putative nicotinate phosphoribosyltransferase; Provisional
Pssm-ID: 236407 [Multi-domain] Cd Length: 463 Bit Score: 42.96 E-value: 4.66e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 61 GGEY--TVFAGLEECVK-FLANfKLTDEEID-----FVQECLPGSEEAFCDYLRGLD-CSDVEVYAIPEGSVVFPKVPLM 131
Cdd:PRK09198 38 GGRYdkVVFFGLQYFLKeYLIQ-PITEAFIDeakalLVAHGLPFNRAGWRRIVDKYGgYLPLRIKAVPEGSVVPVHNVLM 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30682074 132 RVEGP----VGVVQLLETPFLNLVNFASLVATNAARHR----FVAGKSKSLLE--------FGARRAQGP-DGAISASky 194
Cdd:PRK09198 117 TIENTdpefFWLPNYLETLLLRNVWYPSTVATISWEYKqlirQYLEKTADDLDflpfqlhdFGARGMSSLeSAALGGA-- 194
|
170
....*....|....*
gi 30682074 195 CYLGGFDATSNVAAG 209
Cdd:PRK09198 195 AHLVSFLGTDTIPAL 209
|
|
| |
