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Conserved domains on  [gi|15217465|ref|NP_177295|]
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receptor like protein 11 [Arabidopsis thaliana]

Protein Classification

leucine-rich repeat domain-containing protein( domain architecture ID 1000136)

leucine-rich repeat (LRR) domain-containing protein may participate in protein-protein interactions

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PLN00113 super family cl33413
leucine-rich repeat receptor-like protein kinase; Provisional
 10-708 7.84e-79

leucine-rich repeat receptor-like protein kinase; Provisional


The actual alignment was detected with superfamily member PLN00113:

Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 273.26  E-value: 7.84e-79
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217465   10 YCIITIYFSFLihslaspSLHFCRHDQRDGLLKFRDEFPIFESKSSPWNKTTDCCSWDGVTCDDKSgQVISLDLRSTllN 89
Cdd:PLN00113  11 YLIFMLFFLFL-------NFSMLHAEELELLLSFKSSINDPLKYLSNWNSSADVCLWQGITCNNSS-RVVSIDLSGK--N 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217465   90 SSLKTNSSLFRLQYLRHLDLSGCNLHGEIPSSLGNLS-RLENLELSSNRLVGEIPYsiGNLKQLRNLSLGDNDLIGEIPs 168
Cdd:PLN00113  81 ISGKISSAIFRLPYIQTINLSNNQLSGPIPDDIFTTSsSLRYLNLSNNNFTGSIPR--GSIPNLETLDLSNNMLSGEIP- 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217465  169 slgnlsllldldlwnnslvgevpASIGNLNELRVMSLDRNSLSGSIPISFTNLTKLsEFriffnnftslpsdlsgfhnlv 248
Cdd:PLN00113 158 -----------------------NDIGSFSSLKVLDLGGNVLVGKIPNSLTNLTSL-EF--------------------- 192

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217465  249 tFDISANSFSGHFPKFLFSIPSLAWVSMDRNQFSG--PIEFANISSsskLQNLILTRNKLDGSIPESISKFLNLVLLDVA 326
Cdd:PLN00113 193 -LTLASNQLVGQIPRELGQMKSLKWIYLGYNNLSGeiPYEIGGLTS---LNHLDLVYNNLTGPIPSSLGNLKNLQYLFLY 268

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217465  327 HNNISGPVPRSMSKLVSLRIFGFSNNKLEGEVPSWLWRLSStmlshnsfssfekiysketmIQVLDLSFNSFRGTFPVWI 406
Cdd:PLN00113 269 QNKLSGPIPPSIFSLQKLISLDLSDNSLSGEIPELVIQLQN--------------------LEILHLFSNNFTGKIPVAL 328

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217465  407 CKLKGLHFLDLSNNLFNGSIPLCL-RNFNLTGLILGNNKFSGTLPDIFANNTNLQSLDVSGNQLEGKFPKSLINCKGLHF 485
Cdd:PLN00113 329 TSLPRLQVLQLWSNKFSGEIPKNLgKHNNLTVLDLSTNNLTGEIPEGLCSSGNLFKLILFSNSLEGEIPKSLGACRSLRR 408

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217465  486 VNVESNKIKDTFPSWLGSLPSLQVLILRSNDFYGPLyhPSMSIGFQGLRIIDISHNGFSGVLPPNFFSSWREMITLVHGS 565
Cdd:PLN00113 409 VRLQDNSFSGELPSEFTKLPLVYFLDISNNNLQGRI--NSRKWDMPSLQMLSLARNKFFGGLPDSFGSKRLENLDLSRNQ 486

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217465  566 YEyiediqnysliyrsmEMVNKGVeMSFERIRQdfraIDFSENRIYGEIPESIGCLEELRLLNLSGNAFTSDIPRVWENL 645
Cdd:PLN00113 487 FS---------------GAVPRKL-GSLSELMQ----LKLSENKLSGEIPDELSSCKKLVSLDLSHNQLSGQIPASFSEM 546

                        650       660       670       680       690       700
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 15217465  646 TKLETLDLSRNKLSGQIPQDLGKLSFLSYMNFSHNRLQGPVPRGTQFQRQRCSSFLDNHRLYG 708
Cdd:PLN00113 547 PVLSQLDLSQNQLSGEIPKNLGNVESLVQVNISHNHLHGSLPSTGAFLAINASAVAGNIDLCG 609
 
Name Accession Description Interval E-value
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 10-708 7.84e-79

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 273.26  E-value: 7.84e-79
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217465   10 YCIITIYFSFLihslaspSLHFCRHDQRDGLLKFRDEFPIFESKSSPWNKTTDCCSWDGVTCDDKSgQVISLDLRSTllN 89
Cdd:PLN00113  11 YLIFMLFFLFL-------NFSMLHAEELELLLSFKSSINDPLKYLSNWNSSADVCLWQGITCNNSS-RVVSIDLSGK--N 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217465   90 SSLKTNSSLFRLQYLRHLDLSGCNLHGEIPSSLGNLS-RLENLELSSNRLVGEIPYsiGNLKQLRNLSLGDNDLIGEIPs 168
Cdd:PLN00113  81 ISGKISSAIFRLPYIQTINLSNNQLSGPIPDDIFTTSsSLRYLNLSNNNFTGSIPR--GSIPNLETLDLSNNMLSGEIP- 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217465  169 slgnlsllldldlwnnslvgevpASIGNLNELRVMSLDRNSLSGSIPISFTNLTKLsEFriffnnftslpsdlsgfhnlv 248
Cdd:PLN00113 158 -----------------------NDIGSFSSLKVLDLGGNVLVGKIPNSLTNLTSL-EF--------------------- 192

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217465  249 tFDISANSFSGHFPKFLFSIPSLAWVSMDRNQFSG--PIEFANISSsskLQNLILTRNKLDGSIPESISKFLNLVLLDVA 326
Cdd:PLN00113 193 -LTLASNQLVGQIPRELGQMKSLKWIYLGYNNLSGeiPYEIGGLTS---LNHLDLVYNNLTGPIPSSLGNLKNLQYLFLY 268

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217465  327 HNNISGPVPRSMSKLVSLRIFGFSNNKLEGEVPSWLWRLSStmlshnsfssfekiysketmIQVLDLSFNSFRGTFPVWI 406
Cdd:PLN00113 269 QNKLSGPIPPSIFSLQKLISLDLSDNSLSGEIPELVIQLQN--------------------LEILHLFSNNFTGKIPVAL 328

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217465  407 CKLKGLHFLDLSNNLFNGSIPLCL-RNFNLTGLILGNNKFSGTLPDIFANNTNLQSLDVSGNQLEGKFPKSLINCKGLHF 485
Cdd:PLN00113 329 TSLPRLQVLQLWSNKFSGEIPKNLgKHNNLTVLDLSTNNLTGEIPEGLCSSGNLFKLILFSNSLEGEIPKSLGACRSLRR 408

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217465  486 VNVESNKIKDTFPSWLGSLPSLQVLILRSNDFYGPLyhPSMSIGFQGLRIIDISHNGFSGVLPPNFFSSWREMITLVHGS 565
Cdd:PLN00113 409 VRLQDNSFSGELPSEFTKLPLVYFLDISNNNLQGRI--NSRKWDMPSLQMLSLARNKFFGGLPDSFGSKRLENLDLSRNQ 486

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217465  566 YEyiediqnysliyrsmEMVNKGVeMSFERIRQdfraIDFSENRIYGEIPESIGCLEELRLLNLSGNAFTSDIPRVWENL 645
Cdd:PLN00113 487 FS---------------GAVPRKL-GSLSELMQ----LKLSENKLSGEIPDELSSCKKLVSLDLSHNQLSGQIPASFSEM 546

                        650       660       670       680       690       700
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 15217465  646 TKLETLDLSRNKLSGQIPQDLGKLSFLSYMNFSHNRLQGPVPRGTQFQRQRCSSFLDNHRLYG 708
Cdd:PLN00113 547 PVLSQLDLSQNQLSGEIPKNLGNVESLVQVNISHNHLHGSLPSTGAFLAINASAVAGNIDLCG 609
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
81-460 2.14e-25

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 109.64  E-value: 2.14e-25
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217465  81 LDLRSTLLNSSLKTNSSLFRLQYLRHLDLSGCNlhgeipsSLGNLSRLENLELSSNRLVgEIPYSIGNLKQLRNLSLGDN 160
Cdd:COG4886  75 LLLSLLLLSLLLLGLTDLGDLTNLTELDLSGNE-------ELSNLTNLESLDLSGNQLT-DLPEELANLTNLKELDLSNN 146

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217465 161 DLigeipsslgnlsllldldlwnnslvGEVPASIGNLNELRVMSLDRNSLSgSIPISFTNLTKLSEFRIFFNNFTSLPSD 240
Cdd:COG4886 147 QL-------------------------TDLPEPLGNLTNLKSLDLSNNQLT-DLPEELGNLTNLKELDLSNNQITDLPEP 200

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217465 241 LSGFHNLVTFDISANSFSgHFPKFLFSIPSLAWVSMDRNQFSgpiEFANISSSSKLQNLILTRNKLdGSIPESiSKFLNL 320
Cdd:COG4886 201 LGNLTNLEELDLSGNQLT-DLPEPLANLTNLETLDLSNNQLT---DLPELGNLTNLEELDLSNNQL-TDLPPL-ANLTNL 274

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217465 321 VLLDVAHNNISGPVPRSMSKLVSLRIFGFSNNKLEGEVPSWLWRLSSTMLSHNSFSSFEKIYSKETMIQVLDLSFNSFRG 400
Cdd:COG4886 275 KTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLL 354

                       330       340       350       360       370       380
                ....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217465 401 TFPVWICKLKGLHFLDLSNNLFNGSIPLCLRNFNLTGLILGNNKFSGTLPDIFANNTNLQ 460
Cdd:COG4886 355 LLNLLSLLLTLLLTLGLLGLLEATLLTLALLLLTLLLLLLTTTAGVLLLTLALLDAVNTE 414
LRRNT_2 pfam08263
Leucine rich repeat N-terminal domain; Leucine Rich Repeats pfam00560 are short sequence ...
 35-72 1.82e-08

Leucine rich repeat N-terminal domain; Leucine Rich Repeats pfam00560 are short sequence motifs present in a number of proteins with diverse functions and cellular locations. Leucine Rich Repeats are often flanked by cysteine rich domains. This domain is often found at the N-terminus of tandem leucine rich repeats.


Pssm-ID: 462411 [Multi-domain]  Cd Length: 41  Bit Score: 50.76  E-value: 1.82e-08
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 15217465    35 DQRDGLLKFRDEFPIFESKSSPWN-KTTDCCSWDGVTCD 72
Cdd:pfam08263   3 DDGQALLAFKSSLNDPPGALSSWNsSSSDPCSWTGVTCD 41
LRR_RI cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ...
 262-478 1.72e-06

Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).


Pssm-ID: 238064 [Multi-domain]  Cd Length: 319  Bit Score: 50.82  E-value: 1.72e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217465 262 PKFLFSIPSLAWVSMDRNQFS--GPIEFANISSSSKLQNLILTRNKLDGsipeSISKFLNLVLLDVAHNnisgpvprsms 339
Cdd:cd00116  74 LQGLTKGCGLQELDLSDNALGpdGCGVLESLLRSSSLQELKLNNNGLGD----RGLRLLAKGLKDLPPA----------- 138

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217465 340 klvsLRIFGFSNNKLEGEvpswlwrlSSTMLShnsfssfeKIYSKETMIQVLDLSFNSFRGTFPVWICK----LKGLHFL 415
Cdd:cd00116 139 ----LEKLVLGRNRLEGA--------SCEALA--------KALRANRDLKELNLANNGIGDAGIRALAEglkaNCNLEVL 198

                       170       180       190       200       210       220       230
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 15217465 416 DLSNNLFN--GSIPLC---LRNFNLTGLILGNNKFSGT-----LPDIFANNTNLQSLDVSGNQLEGKFPKSLI 478
Cdd:cd00116 199 DLNNNGLTdeGASALAetlASLKSLEVLNLGDNNLTDAgaaalASALLSPNISLLTLSLSCNDITDDGAKDLA 271
 
Name Accession Description Interval E-value
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 10-708 7.84e-79

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 273.26  E-value: 7.84e-79
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217465   10 YCIITIYFSFLihslaspSLHFCRHDQRDGLLKFRDEFPIFESKSSPWNKTTDCCSWDGVTCDDKSgQVISLDLRSTllN 89
Cdd:PLN00113  11 YLIFMLFFLFL-------NFSMLHAEELELLLSFKSSINDPLKYLSNWNSSADVCLWQGITCNNSS-RVVSIDLSGK--N 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217465   90 SSLKTNSSLFRLQYLRHLDLSGCNLHGEIPSSLGNLS-RLENLELSSNRLVGEIPYsiGNLKQLRNLSLGDNDLIGEIPs 168
Cdd:PLN00113  81 ISGKISSAIFRLPYIQTINLSNNQLSGPIPDDIFTTSsSLRYLNLSNNNFTGSIPR--GSIPNLETLDLSNNMLSGEIP- 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217465  169 slgnlsllldldlwnnslvgevpASIGNLNELRVMSLDRNSLSGSIPISFTNLTKLsEFriffnnftslpsdlsgfhnlv 248
Cdd:PLN00113 158 -----------------------NDIGSFSSLKVLDLGGNVLVGKIPNSLTNLTSL-EF--------------------- 192

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217465  249 tFDISANSFSGHFPKFLFSIPSLAWVSMDRNQFSG--PIEFANISSsskLQNLILTRNKLDGSIPESISKFLNLVLLDVA 326
Cdd:PLN00113 193 -LTLASNQLVGQIPRELGQMKSLKWIYLGYNNLSGeiPYEIGGLTS---LNHLDLVYNNLTGPIPSSLGNLKNLQYLFLY 268

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217465  327 HNNISGPVPRSMSKLVSLRIFGFSNNKLEGEVPSWLWRLSStmlshnsfssfekiysketmIQVLDLSFNSFRGTFPVWI 406
Cdd:PLN00113 269 QNKLSGPIPPSIFSLQKLISLDLSDNSLSGEIPELVIQLQN--------------------LEILHLFSNNFTGKIPVAL 328

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217465  407 CKLKGLHFLDLSNNLFNGSIPLCL-RNFNLTGLILGNNKFSGTLPDIFANNTNLQSLDVSGNQLEGKFPKSLINCKGLHF 485
Cdd:PLN00113 329 TSLPRLQVLQLWSNKFSGEIPKNLgKHNNLTVLDLSTNNLTGEIPEGLCSSGNLFKLILFSNSLEGEIPKSLGACRSLRR 408

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217465  486 VNVESNKIKDTFPSWLGSLPSLQVLILRSNDFYGPLyhPSMSIGFQGLRIIDISHNGFSGVLPPNFFSSWREMITLVHGS 565
Cdd:PLN00113 409 VRLQDNSFSGELPSEFTKLPLVYFLDISNNNLQGRI--NSRKWDMPSLQMLSLARNKFFGGLPDSFGSKRLENLDLSRNQ 486

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217465  566 YEyiediqnysliyrsmEMVNKGVeMSFERIRQdfraIDFSENRIYGEIPESIGCLEELRLLNLSGNAFTSDIPRVWENL 645
Cdd:PLN00113 487 FS---------------GAVPRKL-GSLSELMQ----LKLSENKLSGEIPDELSSCKKLVSLDLSHNQLSGQIPASFSEM 546

                        650       660       670       680       690       700
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 15217465  646 TKLETLDLSRNKLSGQIPQDLGKLSFLSYMNFSHNRLQGPVPRGTQFQRQRCSSFLDNHRLYG 708
Cdd:PLN00113 547 PVLSQLDLSQNQLSGEIPKNLGNVESLVQVNISHNHLHGSLPSTGAFLAINASAVAGNIDLCG 609
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
81-460 2.14e-25

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 109.64  E-value: 2.14e-25
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217465  81 LDLRSTLLNSSLKTNSSLFRLQYLRHLDLSGCNlhgeipsSLGNLSRLENLELSSNRLVgEIPYSIGNLKQLRNLSLGDN 160
Cdd:COG4886  75 LLLSLLLLSLLLLGLTDLGDLTNLTELDLSGNE-------ELSNLTNLESLDLSGNQLT-DLPEELANLTNLKELDLSNN 146

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217465 161 DLigeipsslgnlsllldldlwnnslvGEVPASIGNLNELRVMSLDRNSLSgSIPISFTNLTKLSEFRIFFNNFTSLPSD 240
Cdd:COG4886 147 QL-------------------------TDLPEPLGNLTNLKSLDLSNNQLT-DLPEELGNLTNLKELDLSNNQITDLPEP 200

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217465 241 LSGFHNLVTFDISANSFSgHFPKFLFSIPSLAWVSMDRNQFSgpiEFANISSSSKLQNLILTRNKLdGSIPESiSKFLNL 320
Cdd:COG4886 201 LGNLTNLEELDLSGNQLT-DLPEPLANLTNLETLDLSNNQLT---DLPELGNLTNLEELDLSNNQL-TDLPPL-ANLTNL 274

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217465 321 VLLDVAHNNISGPVPRSMSKLVSLRIFGFSNNKLEGEVPSWLWRLSSTMLSHNSFSSFEKIYSKETMIQVLDLSFNSFRG 400
Cdd:COG4886 275 KTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLL 354

                       330       340       350       360       370       380
                ....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217465 401 TFPVWICKLKGLHFLDLSNNLFNGSIPLCLRNFNLTGLILGNNKFSGTLPDIFANNTNLQ 460
Cdd:COG4886 355 LLNLLSLLLTLLLTLGLLGLLEATLLTLALLLLTLLLLLLTTTAGVLLLTLALLDAVNTE 414
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
86-459 1.22e-23

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 104.25  E-value: 1.22e-23
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217465  86 TLLNSSLKTNSSLFRLQYLRHLDLSGCNLHGEIPSSLGNLSRLENLELSSNRLVGEIPYSIGNLKQLRNLSLGDNDLIGE 165
Cdd:COG4886   3 LLLLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLL 82

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217465 166 IPSSLGNLSLLLDLDLWNNSLVGevPASIGNLNELRVMSLDRNSLSgSIPISFTNLTKLSEFRIFFNNFTSLPSDLSGFH 245
Cdd:COG4886  83 SLLLLGLTDLGDLTNLTELDLSG--NEELSNLTNLESLDLSGNQLT-DLPEELANLTNLKELDLSNNQLTDLPEPLGNLT 159

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217465 246 NLVTFDISANSFSGhFPKFLFSIPSLAWVSMDRNQFSG-PIEFANIsssSKLQNLILTRNKLdGSIPESISKFLNLVLLD 324
Cdd:COG4886 160 NLKSLDLSNNQLTD-LPEELGNLTNLKELDLSNNQITDlPEPLGNL---TNLEELDLSGNQL-TDLPEPLANLTNLETLD 234

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217465 325 VAHNNISgPVPrSMSKLVSLRIFGFSNNKLEGEVPSW-LWRLSSTMLSHNSFSSFEKIYSKETMIQVLDLSFNSFRGTFP 403
Cdd:COG4886 235 LSNNQLT-DLP-ELGNLTNLEELDLSNNQLTDLPPLAnLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLE 312

                       330       340       350       360       370
                ....*....|....*....|....*....|....*....|....*....|....*.
gi 15217465 404 VWICKLKGLHFLDLSNNLFNGSIPLCLRNFNLTGLILGNNKFSGTLPDIFANNTNL 459
Cdd:COG4886 313 LLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLT 368
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
193-517 2.83e-20

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 94.23  E-value: 2.83e-20
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217465 193 SIGNLNELRVMSLDRNSLSGSIPISFTNLTKLSEFRIFFNNFTSLPSDLSGFHNLVTFDISANsfsghfpKFLFSIPSLA 272
Cdd:COG4886  44 SLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGN-------EELSNLTNLE 116

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217465 273 WVSMDRNQFSG-PIEFANISsssKLQNLILTRNKLDgSIPESISKFLNLVLLDVAHNNISGpVPRSMSKLVSLRIFGFSN 351
Cdd:COG4886 117 SLDLSGNQLTDlPEELANLT---NLKELDLSNNQLT-DLPEPLGNLTNLKSLDLSNNQLTD-LPEELGNLTNLKELDLSN 191

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217465 352 NKLEgEVPSWLWRLSStmlshnsfssfekiysketmIQVLDLSFNSFRgTFPVWICKLKGLHFLDLSNNLFNgSIPLCLR 431
Cdd:COG4886 192 NQIT-DLPEPLGNLTN--------------------LEELDLSGNQLT-DLPEPLANLTNLETLDLSNNQLT-DLPELGN 248

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217465 432 NFNLTGLILGNNKFSgTLPDIfANNTNLQSLDVSGNQLEGKFPKSLINCKGLHFVNVESNKIKDTFPSWLGSLPSLQVLI 511
Cdd:COG4886 249 LTNLEELDLSNNQLT-DLPPL-ANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLL 326


                ....*.
gi 15217465 512 LRSNDF 517
Cdd:COG4886 327 LLLLKG 332
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
202-517 5.80e-20

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 93.07  E-value: 5.80e-20
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217465 202 VMSLDRNSLSGSIPISFTNLTKLSEFRIFFNNFTSLPSDLSGFHNLVTFDISANSFSGHFPKFLFSIPSLAWVSMDRNQf 281
Cdd:COG4886   2 LLLLLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLL- 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217465 282 SGPIEFANISSSSKLQNLIltrnKLDGSIPESISKFLNLVLLDVAHNNISGpVPRSMSKLVSLRIFGFSNNKLEgEVPSW 361
Cdd:COG4886  81 LLSLLLLGLTDLGDLTNLT----ELDLSGNEELSNLTNLESLDLSGNQLTD-LPEELANLTNLKELDLSNNQLT-DLPEP 154

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217465 362 LWRLSStmlshnsfssfekiysketmIQVLDLSFNSFRgTFPVWICKLKGLHFLDLSNNLFNgSIPLCLRNF-NLTGLIL 440
Cdd:COG4886 155 LGNLTN--------------------LKSLDLSNNQLT-DLPEELGNLTNLKELDLSNNQIT-DLPEPLGNLtNLEELDL 212

                       250       260       270       280       290       300       310
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 15217465 441 GNNKFSgTLPDIFANNTNLQSLDVSGNQLEgKFPkSLINCKGLHFVNVESNKIKDTFPswLGSLPSLQVLILRSNDF 517
Cdd:COG4886 213 SGNQLT-DLPEPLANLTNLETLDLSNNQLT-DLP-ELGNLTNLEELDLSNNQLTDLPP--LANLTNLKTLDLSNNQL 284
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
406-682 1.82e-19

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 91.53  E-value: 1.82e-19
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217465 406 ICKLKGLHFLDLSNNLFNGSIPlclrnfNLTGLILGNNKFSgTLPDIFANNTNLQSLDVSGNQLEgKFPKSLINCKGLHF 485
Cdd:COG4886  92 LGDLTNLTELDLSGNEELSNLT------NLESLDLSGNQLT-DLPEELANLTNLKELDLSNNQLT-DLPEPLGNLTNLKS 163

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217465 486 VNVESNKIKDtFPSWLGSLPSLQVLILRSNdfygplyhpsmsigfqglRIIDIshngfsgvlpPNFFSSWREMITLvhgs 565
Cdd:COG4886 164 LDLSNNQLTD-LPEELGNLTNLKELDLSNN------------------QITDL----------PEPLGNLTNLEEL---- 210

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217465 566 yeyiediqnysliyrsmemvnkgvemsferirqdfraiDFSENRIyGEIPESIGCLEELRLLNLSGNAFTsDIPRVwENL 645
Cdd:COG4886 211 --------------------------------------DLSGNQL-TDLPEPLANLTNLETLDLSNNQLT-DLPEL-GNL 249

                       250       260       270
                ....*....|....*....|....*....|....*..
gi 15217465 646 TKLETLDLSRNKLSGqIPqDLGKLSFLSYMNFSHNRL 682
Cdd:COG4886 250 TNLEELDLSNNQLTD-LP-PLANLTNLKTLDLSNNQL 284
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
293-684 2.86e-19

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 91.15  E-value: 2.86e-19
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217465 293 SSKLQNLILTRNKLDGSIPESISKFLNLVLLDVAHNNISGPVPRSMSKLVSLRIFGFSNNKLEGEVPSWLWRLSSTMLSH 372
Cdd:COG4886   3 LLLLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLL 82

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217465 373 NSFSSFEKIYSKETMIQVLDLSFNSFrgtfpvwICKLKGLHFLDLSNNLFNgSIPLCLRNF-NLTGLILGNNKFSgTLPD 451
Cdd:COG4886  83 SLLLLGLTDLGDLTNLTELDLSGNEE-------LSNLTNLESLDLSGNQLT-DLPEELANLtNLKELDLSNNQLT-DLPE 153

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217465 452 IFANNTNLQSLDVSGNQLEGkFPKSLINCKGLHFVNVESNKIKDtFPSWLGSLPSLQVLILRSNDfygpLYHPSMSIG-F 530
Cdd:COG4886 154 PLGNLTNLKSLDLSNNQLTD-LPEELGNLTNLKELDLSNNQITD-LPEPLGNLTNLEELDLSGNQ----LTDLPEPLAnL 227

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217465 531 QGLRIIDISHNGFSgvlppnffsswremitlvhgsyeyiediqnysliyrsmemvnkgvemsferirqdfraidfsenri 610
Cdd:COG4886 228 TNLETLDLSNNQLT------------------------------------------------------------------ 241

                       330       340       350       360       370       380       390
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 15217465 611 ygEIPEsIGCLEELRLLNLSGNAFTsDIPrVWENLTKLETLDLSRNKLSGQIPQDLGKLSFLSYMNFSHNRLQG 684
Cdd:COG4886 242 --DLPE-LGNLTNLEELDLSNNQLT-DLP-PLANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNL 310
PLN03150 PLN03150
hypothetical protein; Provisional
 66-167 8.65e-17

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 84.48  E-value: 8.65e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217465   66 WDGVTC--DDKSGQ-VIS-LDLRSTLLNSSLKTNSSlfRLQYLRHLDLSGCNLHGEIPSSLGNLSRLENLELSSNRLVGE 141
Cdd:PLN03150 404 WSGADCqfDSTKGKwFIDgLGLDNQGLRGFIPNDIS--KLRHLQSINLSGNSIRGNIPPSLGSITSLEVLDLSYNSFNGS 481

                         90       100
                 ....*....|....*....|....*.
gi 15217465  142 IPYSIGNLKQLRNLSLGDNDLIGEIP 167
Cdd:PLN03150 482 IPESLGQLTSLRILNLNGNSLSGRVP 507
PLN03150 PLN03150
hypothetical protein; Provisional
 588-709 3.72e-13

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 72.93  E-value: 3.72e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217465  588 GVEMSFERIRQDF--RAIDFSENRIYGEIPESIGCLEELRLLNLSGNAFTSDIPRVWENLTKLETLDLSRNKLSGQIPQD 665
Cdd:PLN03150 406 GADCQFDSTKGKWfiDGLGLDNQGLRGFIPNDISKLRHLQSINLSGNSIRGNIPPSLGSITSLEVLDLSYNSFNGSIPES 485

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 15217465  666 LGKLSFLSYMNFSHNRLQGPVP--------RGTQFqrqrcsSFLDNHRLYGL 709
Cdd:PLN03150 486 LGQLTSLRILNLNGNSLSGRVPaalggrllHRASF------NFTDNAGLCGI 531
PLN03150 PLN03150
hypothetical protein; Provisional
 289-362 1.97e-11

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 67.53  E-value: 1.97e-11
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 15217465  289 NISSSSKLQNLILTRNKLDGSIPESISKFLNLVLLDVAHNNISGPVPRSMSKLVSLRIFGFSNNKLEGEVPSWL 362
Cdd:PLN03150 437 DISKLRHLQSINLSGNSIRGNIPPSLGSITSLEVLDLSYNSFNGSIPESLGQLTSLRILNLNGNSLSGRVPAAL 510
PLN03150 PLN03150
hypothetical protein; Provisional
 128-215 1.06e-08

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 58.67  E-value: 1.06e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217465  128 LENLELSSNRLVGEIPYSIGNLKQLRNLSLGDNDLIGEIPSSLGNLSLLLDLDLWNNSLVGEVPASIGNLNELRVMSLDR 207
Cdd:PLN03150 420 IDGLGLDNQGLRGFIPNDISKLRHLQSINLSGNSIRGNIPPSLGSITSLEVLDLSYNSFNGSIPESLGQLTSLRILNLNG 499


                 ....*...
gi 15217465  208 NSLSGSIP 215
Cdd:PLN03150 500 NSLSGRVP 507
LRRNT_2 pfam08263
Leucine rich repeat N-terminal domain; Leucine Rich Repeats pfam00560 are short sequence ...
 35-72 1.82e-08

Leucine rich repeat N-terminal domain; Leucine Rich Repeats pfam00560 are short sequence motifs present in a number of proteins with diverse functions and cellular locations. Leucine Rich Repeats are often flanked by cysteine rich domains. This domain is often found at the N-terminus of tandem leucine rich repeats.


Pssm-ID: 462411 [Multi-domain]  Cd Length: 41  Bit Score: 50.76  E-value: 1.82e-08
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 15217465    35 DQRDGLLKFRDEFPIFESKSSPWN-KTTDCCSWDGVTCD 72
Cdd:pfam08263   3 DDGQALLAFKSSLNDPPGALSSWNsSSSDPCSWTGVTCD 41
PLN03150 PLN03150
hypothetical protein; Provisional
 237-352 7.55e-08

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 55.98  E-value: 7.55e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217465  237 LPSDLSGFHNLVTFDISANSFSGHFPKFLFSIPSLawvsmdrnqfsgpiefanissssklQNLILTRNKLDGSIPESISK 316
Cdd:PLN03150 434 IPNDISKLRHLQSINLSGNSIRGNIPPSLGSITSL-------------------------EVLDLSYNSFNGSIPESLGQ 488

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 15217465  317 FLNLVLLDVAHNNISGPVPRSM-SKLVSLRIFGFSNN 352
Cdd:PLN03150 489 LTSLRILNLNGNSLSGRVPAALgGRLLHRASFNFTDN 525
PLN03150 PLN03150
hypothetical protein; Provisional
 437-519 3.57e-07

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 53.67  E-value: 3.57e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217465  437 GLILGNNKFSGTLPDIFANNTNLQSLDVSGNQLEGKFPKSLINCKGLHFVNVESNKIKDTFPSWLGSLPSLQVLILRSND 516
Cdd:PLN03150 422 GLGLDNQGLRGFIPNDISKLRHLQSINLSGNSIRGNIPPSLGSITSLEVLDLSYNSFNGSIPESLGQLTSLRILNLNGNS 501


                 ...
gi 15217465  517 FYG 519
Cdd:PLN03150 502 LSG 504
PLN03150 PLN03150
hypothetical protein; Provisional
 383-477 9.26e-07

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 52.51  E-value: 9.26e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217465  383 SKETMIQVLDLSFNSFRGTFPVWICKLKGLHFLDLSNNLFNGSIPLCLrnfnltglilgnnkfsGTLpdifannTNLQSL 462
Cdd:PLN03150 439 SKLRHLQSINLSGNSIRGNIPPSLGSITSLEVLDLSYNSFNGSIPESL----------------GQL-------TSLRIL 495

                         90
                 ....*....|....*
gi 15217465  463 DVSGNQLEGKFPKSL 477
Cdd:PLN03150 496 NLNGNSLSGRVPAAL 510
PLN03150 PLN03150
hypothetical protein; Provisional
 378-505 1.70e-06

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 51.36  E-value: 1.70e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217465  378 FEKIYSKeTMIQVLDLSFNSFRGTFPVWICKLKGLHFLDLSNNLFNGSIPLCLrnfnltglilgnnkfsGTLpdifannT 457
Cdd:PLN03150 411 FDSTKGK-WFIDGLGLDNQGLRGFIPNDISKLRHLQSINLSGNSIRGNIPPSL----------------GSI-------T 466

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 15217465  458 NLQSLDVSGNQLEGKFPKSLINCKGLHFVNVESNKIKDTFPSWLGSLP 505
Cdd:PLN03150 467 SLEVLDLSYNSFNGSIPESLGQLTSLRILNLNGNSLSGRVPAALGGRL 514
LRR_RI cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ...
 262-478 1.72e-06

Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).


Pssm-ID: 238064 [Multi-domain]  Cd Length: 319  Bit Score: 50.82  E-value: 1.72e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217465 262 PKFLFSIPSLAWVSMDRNQFS--GPIEFANISSSSKLQNLILTRNKLDGsipeSISKFLNLVLLDVAHNnisgpvprsms 339
Cdd:cd00116  74 LQGLTKGCGLQELDLSDNALGpdGCGVLESLLRSSSLQELKLNNNGLGD----RGLRLLAKGLKDLPPA----------- 138

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217465 340 klvsLRIFGFSNNKLEGEvpswlwrlSSTMLShnsfssfeKIYSKETMIQVLDLSFNSFRGTFPVWICK----LKGLHFL 415
Cdd:cd00116 139 ----LEKLVLGRNRLEGA--------SCEALA--------KALRANRDLKELNLANNGIGDAGIRALAEglkaNCNLEVL 198

                       170       180       190       200       210       220       230
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 15217465 416 DLSNNLFN--GSIPLC---LRNFNLTGLILGNNKFSGT-----LPDIFANNTNLQSLDVSGNQLEGKFPKSLI 478
Cdd:cd00116 199 DLNNNGLTdeGASALAetlASLKSLEVLNLGDNNLTDAgaaalASALLSPNISLLTLSLSCNDITDDGAKDLA 271
PLN03210 PLN03210
Resistant to P. syringae 6; Provisional
 104-383 3.37e-06

Resistant to P. syringae 6; Provisional


Pssm-ID: 215633 [Multi-domain]  Cd Length: 1153  Bit Score: 51.03  E-value: 3.37e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217465   104 LRHLDLSGCNLHGEIPSSLGNLSRLENLELSSNRLVGEIPYSIgNLKQLRNLSLGDNDLIGEIPSSLGNLSLLLDLDLWN 183
Cdd:PLN03210  659 LETLKLSDCSSLVELPSSIQYLNKLEDLDMSRCENLEILPTGI-NLKSLYRLNLSGCSRLKSFPDISTNISWLDLDETAI 737

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217465   184 NSLVGEVPasIGNLNELRVMSLDRNSLSGSIPISFTNLTKLSE--FRIFFNNFTSL---PSDLSGFHNLVTFDISANSFS 258
Cdd:PLN03210  738 EEFPSNLR--LENLDELILCEMKSEKLWERVQPLTPLMTMLSPslTRLFLSDIPSLvelPSSIQNLHKLEHLEIENCINL 815

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217465   259 GHFPKFLfSIPSLawVSMDRNQFSGPIEFANISSSskLQNLILTRNKLDgSIPESISKFLNLVLLDVAHNNISGPVPRSM 338
Cdd:PLN03210  816 ETLPTGI-NLESL--ESLDLSGCSRLRTFPDISTN--ISDLNLSRTGIE-EVPWWIEKFSNLSFLDMNGCNNLQRVSLNI 889

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*
gi 15217465   339 SKLVSLRIFGFSNNkleGEVPSWLWRLSSTMLSHNSFSSFEKIYS 383
Cdd:PLN03210  890 SKLKHLETVDFSDC---GALTEASWNGSPSEVAMATDNIHSKLPS 931
LRR_8 pfam13855
Leucine rich repeat;
623-682 2.22e-05

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 42.51  E-value: 2.22e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217465   623 ELRLLNLSGNAFTSDIPRVWENLTKLETLDLSRNKLSGQIPQDLGKLSFLSYMNFSHNRL 682
Cdd:pfam13855   2 NLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
80-162 3.20e-05

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 47.24  E-value: 3.20e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217465  80 SLDLRSTLLnSSLktNSSLFRLQYLRHLDLSGCNLHgEIPSsLGNLSRLENLELSSNRLvGEIPySIGNLKQLRNLSLGD 159
Cdd:COG4886 209 ELDLSGNQL-TDL--PEPLANLTNLETLDLSNNQLT-DLPE-LGNLTNLEELDLSNNQL-TDLP-PLANLTNLKTLDLSN 281


                ...
gi 15217465 160 NDL 162
Cdd:COG4886 282 NQL 284
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 104-160 3.46e-05

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 45.93  E-value: 3.46e-05
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*....
gi 15217465 104 LRHLDLSGCNLhgEIPSSLGNLSRLENLELSSNRL--VGEIPYSIGNLKQLRNLSLGDN 160
Cdd:cd21340 122 LRVLNISGNNI--DSLEPLAPLRNLEQLDASNNQIsdLEELLDLLSSWPSLRELDLTGN 178
LRR_8 pfam13855
Leucine rich repeat;
104-162 1.12e-04

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 40.59  E-value: 1.12e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 15217465   104 LRHLDLSGCNLHGEIPSSLGNLSRLENLELSSNRLVGEIPYSIGNLKQLRNLSLGDNDL 162
Cdd:pfam13855   3 LRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
LRR_8 pfam13855
Leucine rich repeat;
294-354 1.95e-04

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 39.82  E-value: 1.95e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 15217465   294 SKLQNLILTRNKLDGSIPESISKFLNLVLLDVAHNNISGPVPRSMSKLVSLRIFGFSNNKL 354
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 615-680 2.49e-04

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 43.24  E-value: 2.49e-04
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 15217465 615 PESIGCL-EELRLLNLSGNAFTSDIPrvWENLTKLETLDLSRNKLS--GQIPQDLGKLSFLSYMNFSHN 680
Cdd:cd21340 112 PRSLAALsNSLRVLNISGNNIDSLEP--LAPLRNLEQLDASNNQISdlEELLDLLSSWPSLRELDLTGN 178
LRR_8 pfam13855
Leucine rich repeat;
434-493 2.75e-04

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 39.43  E-value: 2.75e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217465   434 NLTGLILGNNKFSGTLPDIFANNTNLQSLDVSGNQLEGKFPKSLINCKGLHFVNVESNKI 493
Cdd:pfam13855   2 NLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
LRR_8 pfam13855
Leucine rich repeat;
601-658 9.21e-04

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 37.89  E-value: 9.21e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 15217465   601 RAIDFSENRIYGEIPESIGCLEELRLLNLSGNAFTSDIPRVWENLTKLETLDLSRNKL 658
Cdd:pfam13855   4 RSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
LRR_8 pfam13855
Leucine rich repeat;
457-517 1.65e-03

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 37.50  E-value: 1.65e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 15217465   457 TNLQSLDVSGNQLEGKFPKSLINCKGLHFVNVESNKIKDTFPSWLGSLPSLQVLILRSNDF 517
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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