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Conserved domains on  [gi|15221482|ref|NP_176438|]
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Mitochondrial transcription termination factor family protein [Arabidopsis thaliana]

Protein Classification

mTERF domain-containing protein( domain architecture ID 139977)

mTERF (mitochondrial transcription termination factor) domain-containing protein may function as a transcription termination factor that binds promoter DNA and regulates mitochondrial replication and transcription

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
mTERF super family cl47744
mTERF; This family contains one sequence of known function Human mitochondrial transcription ...
 133-310 1.45e-40

mTERF; This family contains one sequence of known function Human mitochondrial transcription termination factor (mTERF) the rest of the family consists of hypothetical proteins none of which have any functional information. mTERF is a multizipper protein possessing three putative leucine zippers one of which is bipartite. The protein binds DNA as a monomer. The leucine zippers are not implicated in a dimerization role as in other leucine zippers.


The actual alignment was detected with superfamily member pfam02536:

Pssm-ID: 460581 [Multi-domain]  Cd Length: 313  Bit Score: 144.28  E-value: 1.45e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15221482   133 VLSLLRSHGFTVSQIS-----IPKLLGKRGHKTLSLYYDFVKEsLEADKSSKYETL-CQSFPQG-NLENK-KRNVSVLRE 204
Cdd:pfam02536  36 KLQFLLSLGASSSDLGkilskYPRILGFKLEETMSTSVDFLKE-IGVDKSSIGGALrSWPSILGmRVGNNiKNNVEYLRE 114

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15221482   205 LGMPHKLLFPLLISVGQpvcgkdrfntslkkvvemgfdpttakfVKALHVSYEMNDKTIEEKVNVYKMLGFAVEDVWVIF 284
Cdd:pfam02536 115 LGVPQKLLARLLISRPQ---------------------------LLALDLVYLMKPKTFEEKVEFLKELGFSVEDVWKII 167

                         170       180
                  ....*....|....*....|....*..
gi 15221482   285 KKWPYSLKYS-EEKITQTIETLKMCGL 310
Cdd:pfam02536 168 KKCPEILGLSiEKKLKKKIEFLKKCGL 194
 
Name Accession Description Interval E-value
mTERF pfam02536
mTERF; This family contains one sequence of known function Human mitochondrial transcription ...
 133-310 1.45e-40

mTERF; This family contains one sequence of known function Human mitochondrial transcription termination factor (mTERF) the rest of the family consists of hypothetical proteins none of which have any functional information. mTERF is a multizipper protein possessing three putative leucine zippers one of which is bipartite. The protein binds DNA as a monomer. The leucine zippers are not implicated in a dimerization role as in other leucine zippers.


Pssm-ID: 460581 [Multi-domain]  Cd Length: 313  Bit Score: 144.28  E-value: 1.45e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15221482   133 VLSLLRSHGFTVSQIS-----IPKLLGKRGHKTLSLYYDFVKEsLEADKSSKYETL-CQSFPQG-NLENK-KRNVSVLRE 204
Cdd:pfam02536  36 KLQFLLSLGASSSDLGkilskYPRILGFKLEETMSTSVDFLKE-IGVDKSSIGGALrSWPSILGmRVGNNiKNNVEYLRE 114

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15221482   205 LGMPHKLLFPLLISVGQpvcgkdrfntslkkvvemgfdpttakfVKALHVSYEMNDKTIEEKVNVYKMLGFAVEDVWVIF 284
Cdd:pfam02536 115 LGVPQKLLARLLISRPQ---------------------------LLALDLVYLMKPKTFEEKVEFLKELGFSVEDVWKII 167

                         170       180
                  ....*....|....*....|....*..
gi 15221482   285 KKWPYSLKYS-EEKITQTIETLKMCGL 310
Cdd:pfam02536 168 KKCPEILGLSiEKKLKKKIEFLKKCGL 194
Mterf smart00733
Mitochondrial termination factor repeats; Human mitochondrial termination factor is a ...
 281-311 2.31e-03

Mitochondrial termination factor repeats; Human mitochondrial termination factor is a DNA-binding protein that acts as a transcription termination factor. Six repeats occur in human mTERF, that also are present in numerous plant proteins.


Pssm-ID: 197848  Cd Length: 31  Bit Score: 35.10  E-value: 2.31e-03
                           10        20        30
                   ....*....|....*....|....*....|.
gi 15221482    281 WVIFKKWPYSLKYSEEKITQTIETLKMCGLR 311
Cdd:smart00733   1 GKIVKKFPQILGYSEKKLKPKVEFLKELGFS 31
 
Name Accession Description Interval E-value
mTERF pfam02536
mTERF; This family contains one sequence of known function Human mitochondrial transcription ...
 133-310 1.45e-40

mTERF; This family contains one sequence of known function Human mitochondrial transcription termination factor (mTERF) the rest of the family consists of hypothetical proteins none of which have any functional information. mTERF is a multizipper protein possessing three putative leucine zippers one of which is bipartite. The protein binds DNA as a monomer. The leucine zippers are not implicated in a dimerization role as in other leucine zippers.


Pssm-ID: 460581 [Multi-domain]  Cd Length: 313  Bit Score: 144.28  E-value: 1.45e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15221482   133 VLSLLRSHGFTVSQIS-----IPKLLGKRGHKTLSLYYDFVKEsLEADKSSKYETL-CQSFPQG-NLENK-KRNVSVLRE 204
Cdd:pfam02536  36 KLQFLLSLGASSSDLGkilskYPRILGFKLEETMSTSVDFLKE-IGVDKSSIGGALrSWPSILGmRVGNNiKNNVEYLRE 114

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15221482   205 LGMPHKLLFPLLISVGQpvcgkdrfntslkkvvemgfdpttakfVKALHVSYEMNDKTIEEKVNVYKMLGFAVEDVWVIF 284
Cdd:pfam02536 115 LGVPQKLLARLLISRPQ---------------------------LLALDLVYLMKPKTFEEKVEFLKELGFSVEDVWKII 167

                         170       180
                  ....*....|....*....|....*..
gi 15221482   285 KKWPYSLKYS-EEKITQTIETLKMCGL 310
Cdd:pfam02536 168 KKCPEILGLSiEKKLKKKIEFLKKCGL 194
Mterf smart00733
Mitochondrial termination factor repeats; Human mitochondrial termination factor is a ...
 281-311 2.31e-03

Mitochondrial termination factor repeats; Human mitochondrial termination factor is a DNA-binding protein that acts as a transcription termination factor. Six repeats occur in human mTERF, that also are present in numerous plant proteins.


Pssm-ID: 197848  Cd Length: 31  Bit Score: 35.10  E-value: 2.31e-03
                           10        20        30
                   ....*....|....*....|....*....|.
gi 15221482    281 WVIFKKWPYSLKYSEEKITQTIETLKMCGLR 311
Cdd:smart00733   1 GKIVKKFPQILGYSEKKLKPKVEFLKELGFS 31
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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