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Conserved domains on  [gi|15221871|ref|NP_175865|]
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F-box family protein-like protein [Arabidopsis thaliana]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
F_box_assoc_1 super family cl44343
F-box protein interaction domain; This model describes a large family of plant domains, with ...
 45-119 3.71e-06

F-box protein interaction domain; This model describes a large family of plant domains, with several hundred members in Arabidopsis thaliana. Most examples are found C-terminal to an F-box (pfam00646), a 60 amino acid motif involved in ubiquitination of target proteins to mark them for degradation. Two-hybid experiments support the idea that most members are interchangeable F-box subunits of SCF E3 complexes. Some members have two copies of this domain.


The actual alignment was detected with superfamily member TIGR01640:

Pssm-ID: 273726 [Multi-domain]  Cd Length: 230  Bit Score: 46.58  E-value: 3.71e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15221871    45 ILHCRGMMCLTLKenNDLAIWKPGSEEFKRIPMvIPGQTTN----LLGFGYDRISNDYKIV-------TKIGFKTYIYAF 113
Cdd:TIGR01640   1 VVPCDGLICFSYG--KRLVVWNPSTGQSRWLPT-PKSRRSNkesdTYFLGYDPIEKQYKVLcfsdrsgNRNQSEHQVYTL 77


                  ....*.
gi 15221871   114 KESCWR 119
Cdd:TIGR01640  78 GSNSWR 83
 
Name Accession Description Interval E-value
F_box_assoc_1 TIGR01640
F-box protein interaction domain; This model describes a large family of plant domains, with ...
 45-119 3.71e-06

F-box protein interaction domain; This model describes a large family of plant domains, with several hundred members in Arabidopsis thaliana. Most examples are found C-terminal to an F-box (pfam00646), a 60 amino acid motif involved in ubiquitination of target proteins to mark them for degradation. Two-hybid experiments support the idea that most members are interchangeable F-box subunits of SCF E3 complexes. Some members have two copies of this domain.


Pssm-ID: 273726 [Multi-domain]  Cd Length: 230  Bit Score: 46.58  E-value: 3.71e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15221871    45 ILHCRGMMCLTLKenNDLAIWKPGSEEFKRIPMvIPGQTTN----LLGFGYDRISNDYKIV-------TKIGFKTYIYAF 113
Cdd:TIGR01640   1 VVPCDGLICFSYG--KRLVVWNPSTGQSRWLPT-PKSRRSNkesdTYFLGYDPIEKQYKVLcfsdrsgNRNQSEHQVYTL 77


                  ....*.
gi 15221871   114 KESCWR 119
Cdd:TIGR01640  78 GSNSWR 83
 
Name Accession Description Interval E-value
F_box_assoc_1 TIGR01640
F-box protein interaction domain; This model describes a large family of plant domains, with ...
 45-119 3.71e-06

F-box protein interaction domain; This model describes a large family of plant domains, with several hundred members in Arabidopsis thaliana. Most examples are found C-terminal to an F-box (pfam00646), a 60 amino acid motif involved in ubiquitination of target proteins to mark them for degradation. Two-hybid experiments support the idea that most members are interchangeable F-box subunits of SCF E3 complexes. Some members have two copies of this domain.


Pssm-ID: 273726 [Multi-domain]  Cd Length: 230  Bit Score: 46.58  E-value: 3.71e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15221871    45 ILHCRGMMCLTLKenNDLAIWKPGSEEFKRIPMvIPGQTTN----LLGFGYDRISNDYKIV-------TKIGFKTYIYAF 113
Cdd:TIGR01640   1 VVPCDGLICFSYG--KRLVVWNPSTGQSRWLPT-PKSRRSNkesdTYFLGYDPIEKQYKVLcfsdrsgNRNQSEHQVYTL 77


                  ....*.
gi 15221871   114 KESCWR 119
Cdd:TIGR01640  78 GSNSWR 83
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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