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Conserved domains on  [gi|15221018|ref|NP_175801|]
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GDSL-motif lipase 3 [Arabidopsis thaliana]

Protein Classification

SGNH/GDSL hydrolase family protein( domain architecture ID 10110850)

SGNH/GDSL hydrolase family protein is a hydrolytic enzyme such as an esterase or lipase; may have multifunctional properties including broad substrate specificity and regiospecificity

CATH:  3.40.50.1110
EC:  3.1.-.-
Gene Ontology:  GO:0016788
PubMed:  15522763|35871440
SCOP:  3001315

Graphical summary

 Zoom to residue level

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Show site features     Horizontal zoom: ×

List of domain hits

Name Accession Description Interval E-value
SGNH_plant_lipase_like cd01837
SGNH_plant_lipase_like, a plant specific subfamily of the SGNH-family of hydrolases, a diverse ...
35-349 3.28e-112

SGNH_plant_lipase_like, a plant specific subfamily of the SGNH-family of hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the Ser-His-Asp(Glu) triad found in other serine hydrolases.


:

Pssm-ID: 238875 [Multi-domain]  Cd Length: 315  Bit Score: 329.58  E-value: 3.28e-112
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15221018  35 ALFVFGDSLFDAGNNNYINTVSsfRSNIWPYGQTNFKFPTGRLSDGP-------EKAWLPSIPPNLQPNNGNNQFTYGVS 107
Cdd:cd01837   2 ALFVFGDSLVDTGNNNYLPTLA--KANFPPYGIDFPGRPTGRFSNGRliidfiaEALGLPLLPPPYLSPNGSSDFLTGVN 79
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15221018 108 FASAGAGAL-AESFLGMVINLGTQLNNFKDVEKSLRSELGDAETKRVFSRAVYLFHIGANDYFYPFSANSSTFKSNskEK 186
Cdd:cd01837  80 FASGGAGILdSTGFLGSVISLSVQLEYFKEYKERLRALVGEEAAADILSKSLFLISIGSNDYLNNYFANPTRQYEV--EA 157
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15221018 187 FVDFVIGNITFVIEEVYKMGGRKFGFLNVGPYECSPNSLIRDRTKIGSCFKPVAELIDMHNKKFPDVLRRLQRQLSGFRY 266
Cdd:cd01837 158 YVPFLVSNISSAIKRLYDLGARKFVVPGLGPLGCLPSQRTLFGGDGGGCLEELNELARLFNAKLKKLLAELRRELPGAKF 237
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15221018 267 ALHDYHTSLSERINSPSKYGFKEGKKACCGSGPLRGINTCGNRigpsqGYGLCENVTDYLFYDSSHLTEKAHRQIAELIW 346
Cdd:cd01837 238 VYADIYNALLDLIQNPAKYGFENTLKACCGTGGPEGGLLCNPC-----GSTVCPDPSKYVFWDGVHPTEAANRIIADALL 312

                ...
gi 15221018 347 NGP 349
Cdd:cd01837 313 SGP 315
 
Name Accession Description Interval E-value
SGNH_plant_lipase_like cd01837
SGNH_plant_lipase_like, a plant specific subfamily of the SGNH-family of hydrolases, a diverse ...
35-349 3.28e-112

SGNH_plant_lipase_like, a plant specific subfamily of the SGNH-family of hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the Ser-His-Asp(Glu) triad found in other serine hydrolases.


Pssm-ID: 238875 [Multi-domain]  Cd Length: 315  Bit Score: 329.58  E-value: 3.28e-112
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15221018  35 ALFVFGDSLFDAGNNNYINTVSsfRSNIWPYGQTNFKFPTGRLSDGP-------EKAWLPSIPPNLQPNNGNNQFTYGVS 107
Cdd:cd01837   2 ALFVFGDSLVDTGNNNYLPTLA--KANFPPYGIDFPGRPTGRFSNGRliidfiaEALGLPLLPPPYLSPNGSSDFLTGVN 79
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15221018 108 FASAGAGAL-AESFLGMVINLGTQLNNFKDVEKSLRSELGDAETKRVFSRAVYLFHIGANDYFYPFSANSSTFKSNskEK 186
Cdd:cd01837  80 FASGGAGILdSTGFLGSVISLSVQLEYFKEYKERLRALVGEEAAADILSKSLFLISIGSNDYLNNYFANPTRQYEV--EA 157
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15221018 187 FVDFVIGNITFVIEEVYKMGGRKFGFLNVGPYECSPNSLIRDRTKIGSCFKPVAELIDMHNKKFPDVLRRLQRQLSGFRY 266
Cdd:cd01837 158 YVPFLVSNISSAIKRLYDLGARKFVVPGLGPLGCLPSQRTLFGGDGGGCLEELNELARLFNAKLKKLLAELRRELPGAKF 237
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15221018 267 ALHDYHTSLSERINSPSKYGFKEGKKACCGSGPLRGINTCGNRigpsqGYGLCENVTDYLFYDSSHLTEKAHRQIAELIW 346
Cdd:cd01837 238 VYADIYNALLDLIQNPAKYGFENTLKACCGTGGPEGGLLCNPC-----GSTVCPDPSKYVFWDGVHPTEAANRIIADALL 312

                ...
gi 15221018 347 NGP 349
Cdd:cd01837 313 SGP 315
PLN03156 PLN03156
GDSL esterase/lipase; Provisional
1-342 1.06e-49

GDSL esterase/lipase; Provisional


Pssm-ID: 178701  Cd Length: 351  Bit Score: 170.31  E-value: 1.06e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15221018    1 MVRLVLIIFFVYTIILSIGSINCidnnnlVTNQAALFVFGDSLFDAGNNNYINTVSsfRSNIWPYGQtNFK--FPTGRLS 78
Cdd:PLN03156   1 MQMHLFLIFFLLLAQLLVLVAET------CAKVPAIIVFGDSSVDAGNNNQISTVA--KSNFEPYGR-DFPggRPTGRFC 71
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15221018   79 DG-------PEKAWL-PSIPPNLQPNNGNNQFTYGVSFASAGAGA-LAESFLGMVINLGTQLNNFKDVEKSLRSELGDAE 149
Cdd:PLN03156  72 NGriapdfiSEAFGLkPAIPAYLDPSYNISDFATGVCFASAGTGYdNATSDVLSVIPLWKELEYYKEYQTKLRAYLGEEK 151
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15221018  150 TKRVFSRAVYLFHIGANDY---FYPFSANSSTFKSNSKEkfvDFVIGNITFVIEEVYKMGGRKFGFLNVGPYECSPnsLI 226
Cdd:PLN03156 152 ANEIISEALYLISIGTNDFlenYYTFPGRRSQYTVSQYQ---DFLIGIAENFVKKLYRLGARKISLGGLPPMGCLP--LE 226
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15221018  227 RDrTKIGSCFKPVAELIDM---HNKKFPDVLRRLQRQLSGFRYALHDYHTSLSERINSPSKYGFKEGKKACCGSGPLRGI 303
Cdd:PLN03156 227 RT-TNLMGGSECVEEYNDValeFNGKLEKLVTKLNKELPGIKLVFSNPYDIFMQIIRNPSAYGFEVTSVACCATGMFEMG 305
                        330       340       350
                 ....*....|....*....|....*....|....*....
gi 15221018  304 NTCgNRIGPSQgyglCENVTDYLFYDSSHLTEKAHRQIA 342
Cdd:PLN03156 306 YLC-NRNNPFT----CSDADKYVFWDSFHPTEKTNQIIA 339
COG3240 COG3240
Phospholipase/lecithinase/hemolysin [Lipid transport and metabolism, General function ...
36-345 4.29e-18

Phospholipase/lecithinase/hemolysin [Lipid transport and metabolism, General function prediction only];


Pssm-ID: 442472 [Multi-domain]  Cd Length: 305  Bit Score: 83.55  E-value: 4.29e-18
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15221018  36 LFVFGDSLFDAGNnnyINTVSSFRSNIWPYGQtnfkfptGRLSDGPekAW---------LPSIPPNLQPNNgnnqftYGV 106
Cdd:COG3240  31 IVVFGDSLSDTGN---LFNLTGGLPPSPPYFG-------GRFSNGP--VWveylaaalgLPLTPSSAGGTN------YAV 92
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15221018 107 SFASAGAGALAESFLGMVINLGTQLNNFKDvekslrselgdAETKRVFSRAVYLFHIGANDYFYPFSANSSTFKSNSKEk 186
Cdd:COG3240  93 GGARTGDGNGVLGGAALLPGLAQQVDAYLA-----------AAGGTADPNALYIVWAGANDLLAALAAVGATPAQAQAA- 160
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15221018 187 fVDFVIGNITFVIEEVYKMGGRKFGFLNVGPYECSPNSLIRDRTKIGScfkpVAELIDMHNKKfpdvlrrLQRQLS--GF 264
Cdd:COG3240 161 -ATAAAANLAAAVGALAAAGARHILVPNLPDLGLTPAAQALGAAAAAL----LSALTAAFNQA-------LAAALPalGV 228
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15221018 265 RYALHDYHTSLSERINSPSKYGFKEGKKACcgsgplrgintcgnrIGPSQGYGLCE-NVTDYLFYDSSHLTEKAHRQIAE 343
Cdd:COG3240 229 NIILFDVNSLFNEIIANPAAYGFTNVTDAC---------------LSGTVSALLCVaNPDTYLFWDGVHPTTAAHRLIAD 293

                ..
gi 15221018 344 LI 345
Cdd:COG3240 294 YA 295
Lipase_GDSL pfam00657
GDSL-like Lipase/Acylhydrolase;
36-345 1.46e-12

GDSL-like Lipase/Acylhydrolase;


Pssm-ID: 459892 [Multi-domain]  Cd Length: 210  Bit Score: 66.06  E-value: 1.46e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15221018    36 LFVFGDSLFDAGNNNyintvssfrsniwpygqtnfkfPTGRLSDGPekAWLPSIPPNLQ-PNNGNNQftyGVSFASAGAG 114
Cdd:pfam00657   1 IVAFGDSLTDGGGDG----------------------PGGRFSWGD--LLADFLARKLGvPGSGYNH---GANFAIGGAT 53
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15221018   115 ALaesflgmviNLGTQLNNFKDVekslrselgDAETKRVFSRAVYLFHIGANDYFYPFSansstfksnSKEKFVDFVIGN 194
Cdd:pfam00657  54 IE---------DLPIQLEQLLRL---------ISDVKDQAKPDLVTIFIGANDLCNFLS---------SPARSKKRVPDL 106
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15221018   195 ITFVIEEVYKM--GGRKFGFLNVGPYECSPNSLirdrtkigsCFKPVAELIDMHNKKFPDVLRRLQRQLSGFRYALHDYh 272
Cdd:pfam00657 107 LDELRANLPQLglGARKFWVHGLGPLGCTPPKG---------CYELYNALAEEYNERLNELVNSLAAAAEDANVVYVDI- 176
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 15221018   273 tslserinspskYGFKEGKKACCGSGPLRgintcgnrigpsqgyglcenvtdylfyDSSHLTEKAHRQIAELI 345
Cdd:pfam00657 177 ------------YGFEDPTDPCCGIGLEP---------------------------DGLHPSEKGYKAVAEAI 210
 
Name Accession Description Interval E-value
SGNH_plant_lipase_like cd01837
SGNH_plant_lipase_like, a plant specific subfamily of the SGNH-family of hydrolases, a diverse ...
35-349 3.28e-112

SGNH_plant_lipase_like, a plant specific subfamily of the SGNH-family of hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the Ser-His-Asp(Glu) triad found in other serine hydrolases.


Pssm-ID: 238875 [Multi-domain]  Cd Length: 315  Bit Score: 329.58  E-value: 3.28e-112
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15221018  35 ALFVFGDSLFDAGNNNYINTVSsfRSNIWPYGQTNFKFPTGRLSDGP-------EKAWLPSIPPNLQPNNGNNQFTYGVS 107
Cdd:cd01837   2 ALFVFGDSLVDTGNNNYLPTLA--KANFPPYGIDFPGRPTGRFSNGRliidfiaEALGLPLLPPPYLSPNGSSDFLTGVN 79
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15221018 108 FASAGAGAL-AESFLGMVINLGTQLNNFKDVEKSLRSELGDAETKRVFSRAVYLFHIGANDYFYPFSANSSTFKSNskEK 186
Cdd:cd01837  80 FASGGAGILdSTGFLGSVISLSVQLEYFKEYKERLRALVGEEAAADILSKSLFLISIGSNDYLNNYFANPTRQYEV--EA 157
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15221018 187 FVDFVIGNITFVIEEVYKMGGRKFGFLNVGPYECSPNSLIRDRTKIGSCFKPVAELIDMHNKKFPDVLRRLQRQLSGFRY 266
Cdd:cd01837 158 YVPFLVSNISSAIKRLYDLGARKFVVPGLGPLGCLPSQRTLFGGDGGGCLEELNELARLFNAKLKKLLAELRRELPGAKF 237
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15221018 267 ALHDYHTSLSERINSPSKYGFKEGKKACCGSGPLRGINTCGNRigpsqGYGLCENVTDYLFYDSSHLTEKAHRQIAELIW 346
Cdd:cd01837 238 VYADIYNALLDLIQNPAKYGFENTLKACCGTGGPEGGLLCNPC-----GSTVCPDPSKYVFWDGVHPTEAANRIIADALL 312

                ...
gi 15221018 347 NGP 349
Cdd:cd01837 313 SGP 315
PLN03156 PLN03156
GDSL esterase/lipase; Provisional
1-342 1.06e-49

GDSL esterase/lipase; Provisional


Pssm-ID: 178701  Cd Length: 351  Bit Score: 170.31  E-value: 1.06e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15221018    1 MVRLVLIIFFVYTIILSIGSINCidnnnlVTNQAALFVFGDSLFDAGNNNYINTVSsfRSNIWPYGQtNFK--FPTGRLS 78
Cdd:PLN03156   1 MQMHLFLIFFLLLAQLLVLVAET------CAKVPAIIVFGDSSVDAGNNNQISTVA--KSNFEPYGR-DFPggRPTGRFC 71
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15221018   79 DG-------PEKAWL-PSIPPNLQPNNGNNQFTYGVSFASAGAGA-LAESFLGMVINLGTQLNNFKDVEKSLRSELGDAE 149
Cdd:PLN03156  72 NGriapdfiSEAFGLkPAIPAYLDPSYNISDFATGVCFASAGTGYdNATSDVLSVIPLWKELEYYKEYQTKLRAYLGEEK 151
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15221018  150 TKRVFSRAVYLFHIGANDY---FYPFSANSSTFKSNSKEkfvDFVIGNITFVIEEVYKMGGRKFGFLNVGPYECSPnsLI 226
Cdd:PLN03156 152 ANEIISEALYLISIGTNDFlenYYTFPGRRSQYTVSQYQ---DFLIGIAENFVKKLYRLGARKISLGGLPPMGCLP--LE 226
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15221018  227 RDrTKIGSCFKPVAELIDM---HNKKFPDVLRRLQRQLSGFRYALHDYHTSLSERINSPSKYGFKEGKKACCGSGPLRGI 303
Cdd:PLN03156 227 RT-TNLMGGSECVEEYNDValeFNGKLEKLVTKLNKELPGIKLVFSNPYDIFMQIIRNPSAYGFEVTSVACCATGMFEMG 305
                        330       340       350
                 ....*....|....*....|....*....|....*....
gi 15221018  304 NTCgNRIGPSQgyglCENVTDYLFYDSSHLTEKAHRQIA 342
Cdd:PLN03156 306 YLC-NRNNPFT----CSDADKYVFWDSFHPTEKTNQIIA 339
fatty_acyltransferase_like cd01846
Fatty acyltransferase-like subfamily of the SGNH hydrolases, a diverse family of lipases and ...
36-345 1.86e-28

Fatty acyltransferase-like subfamily of the SGNH hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the Ser-His-Asp(Glu) triad found in other serine hydrolases. Might catalyze fatty acid transfer between phosphatidylcholine and sterols.


Pssm-ID: 238882 [Multi-domain]  Cd Length: 270  Bit Score: 111.70  E-value: 1.86e-28
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15221018  36 LFVFGDSLFDAGNnnyintvsSFRSNIWPYGQTNFKFPTGRLSDGPekAWLPSIPPNLqpnnGNNQFTYGVSFASAGAGA 115
Cdd:cd01846   2 LVVFGDSLSDTGN--------IFKLTGGSNPPPSPPYFGGRFSNGP--VWVEYLAATL----GLSGLKQGYNYAVGGATA 67
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15221018 116 LAESFLGM---VINLGTQLNNFKDVEKSLRSelgdaetkrvfSRAVYLFHIGANDYFypFSANSSTFKSNSKEKFVDfvi 192
Cdd:cd01846  68 GAYNVPPYpptLPGLSDQVAAFLAAHKLRLP-----------PDTLVAIWIGANDLL--NALDLPQNPDTLVTRAVD--- 131
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15221018 193 gNITFVIEEVYKMGGRKFGFLNVGPYECSPNSLIRDRTKIgscfKPVAELIDMHNKKFPDVLRRLQRQLSGFRYALHDYH 272
Cdd:cd01846 132 -NLFQALQRLYAAGARNFLVLNLPDLGLTPAFQAQGDAVA----ARATALTAAYNAKLAEKLAELKAQHPGVNILLFDTN 206
                       250       260       270       280       290       300       310
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 15221018 273 TSLSERINSPSKYGFKEGKKACCGSgplrgintcgnrIGPSQGYGLCENVTDYLFYDSSHLTEKAHRQIAELI 345
Cdd:cd01846 207 ALFNDILDNPAAYGFTNVTDPCLDY------------VYSYSPREACANPDKYLFWDEVHPTTAVHQLIAEEV 267
COG3240 COG3240
Phospholipase/lecithinase/hemolysin [Lipid transport and metabolism, General function ...
36-345 4.29e-18

Phospholipase/lecithinase/hemolysin [Lipid transport and metabolism, General function prediction only];


Pssm-ID: 442472 [Multi-domain]  Cd Length: 305  Bit Score: 83.55  E-value: 4.29e-18
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15221018  36 LFVFGDSLFDAGNnnyINTVSSFRSNIWPYGQtnfkfptGRLSDGPekAW---------LPSIPPNLQPNNgnnqftYGV 106
Cdd:COG3240  31 IVVFGDSLSDTGN---LFNLTGGLPPSPPYFG-------GRFSNGP--VWveylaaalgLPLTPSSAGGTN------YAV 92
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15221018 107 SFASAGAGALAESFLGMVINLGTQLNNFKDvekslrselgdAETKRVFSRAVYLFHIGANDYFYPFSANSSTFKSNSKEk 186
Cdd:COG3240  93 GGARTGDGNGVLGGAALLPGLAQQVDAYLA-----------AAGGTADPNALYIVWAGANDLLAALAAVGATPAQAQAA- 160
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15221018 187 fVDFVIGNITFVIEEVYKMGGRKFGFLNVGPYECSPNSLIRDRTKIGScfkpVAELIDMHNKKfpdvlrrLQRQLS--GF 264
Cdd:COG3240 161 -ATAAAANLAAAVGALAAAGARHILVPNLPDLGLTPAAQALGAAAAAL----LSALTAAFNQA-------LAAALPalGV 228
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15221018 265 RYALHDYHTSLSERINSPSKYGFKEGKKACcgsgplrgintcgnrIGPSQGYGLCE-NVTDYLFYDSSHLTEKAHRQIAE 343
Cdd:COG3240 229 NIILFDVNSLFNEIIANPAAYGFTNVTDAC---------------LSGTVSALLCVaNPDTYLFWDGVHPTTAAHRLIAD 293

                ..
gi 15221018 344 LI 345
Cdd:COG3240 294 YA 295
Lipase_GDSL pfam00657
GDSL-like Lipase/Acylhydrolase;
36-345 1.46e-12

GDSL-like Lipase/Acylhydrolase;


Pssm-ID: 459892 [Multi-domain]  Cd Length: 210  Bit Score: 66.06  E-value: 1.46e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15221018    36 LFVFGDSLFDAGNNNyintvssfrsniwpygqtnfkfPTGRLSDGPekAWLPSIPPNLQ-PNNGNNQftyGVSFASAGAG 114
Cdd:pfam00657   1 IVAFGDSLTDGGGDG----------------------PGGRFSWGD--LLADFLARKLGvPGSGYNH---GANFAIGGAT 53
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15221018   115 ALaesflgmviNLGTQLNNFKDVekslrselgDAETKRVFSRAVYLFHIGANDYFYPFSansstfksnSKEKFVDFVIGN 194
Cdd:pfam00657  54 IE---------DLPIQLEQLLRL---------ISDVKDQAKPDLVTIFIGANDLCNFLS---------SPARSKKRVPDL 106
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15221018   195 ITFVIEEVYKM--GGRKFGFLNVGPYECSPNSLirdrtkigsCFKPVAELIDMHNKKFPDVLRRLQRQLSGFRYALHDYh 272
Cdd:pfam00657 107 LDELRANLPQLglGARKFWVHGLGPLGCTPPKG---------CYELYNALAEEYNERLNELVNSLAAAAEDANVVYVDI- 176
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 15221018   273 tslserinspskYGFKEGKKACCGSGPLRgintcgnrigpsqgyglcenvtdylfyDSSHLTEKAHRQIAELI 345
Cdd:pfam00657 177 ------------YGFEDPTDPCCGIGLEP---------------------------DGLHPSEKGYKAVAEAI 210
Triacylglycerol_lipase_like cd01847
Triacylglycerol lipase-like subfamily of the SGNH hydrolases, a diverse family of lipases and ...
35-347 1.87e-09

Triacylglycerol lipase-like subfamily of the SGNH hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the Ser-His-Asp(Glu) triad found in other serine hydrolases. Members of this subfamily might hydrolyze triacylglycerol into diacylglycerol and fatty acid anions.


Pssm-ID: 238883  Cd Length: 281  Bit Score: 57.83  E-value: 1.87e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15221018  35 ALFVFGDSLFDAGNNNYIntvssfrsniwpygqTNFKFPTGRLSDGPEKAW--LPSIPPNLQPNNGN----NQFTYGVSF 108
Cdd:cd01847   3 RVVVFGDSLSDVGTYNRA---------------GVGAAGGGRFTVNDGSIWslGVAEGYGLTTGTATpttpGGTNYAQGG 67
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15221018 109 ASAGAGALAESFLGMVINLGTQLNNFkdvekslrselgDAETKRVFSRAVYLFHIGAND-YFYPFSANSSTFKSNSKEKF 187
Cdd:cd01847  68 ARVGDTNNGNGAGAVLPSVTTQIANY------------LAAGGGFDPNALYTVWIGGNDlIAALAALTTATTTQAAAVAA 135
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15221018 188 VDFVIGNITFVIEEVYKMGGRKFGFLNVGPYECSPNslirdrtkIGSCFKPVAELIDMHNKKFPDVLRRLQRQLSGFRYA 267
Cdd:cd01847 136 AATAAADLASQVKNLLDAGARYILVPNLPDVSYTPE--------AAGTPAAAAALASALSQTYNQTLQSGLNQLGANNII 207
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15221018 268 LHDYHTSLSERINSPSKYGFKEGKKACCGSGplrGINTCGNRIGPSQGyglceNVTDYLFYDSSHLTEKAHRQIAELIWN 347
Cdd:cd01847 208 YVDTATLLKEVVANPAAYGFTNTTTPACTST---SAAGSGAATLVTAA-----AQSTYLFADDVHPTPAGHKLIAQYALS 279
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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