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Conserved domains on  [gi|145336647|ref|NP_175618|]
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Mannose-binding lectin superfamily protein [Arabidopsis thaliana]

Protein Classification

jacalin family lectin; zinc metalloproteinase family protein( domain architecture ID 10658524)

jacalin family lectin is a sugar-binding protein containing a jacalin domain| zinc metalloproteinase family protein contains an HEXXH motif characteristic of metallopeptidases; contains a Jacalin-like lectin domain that may bind mono- or oligosaccharides

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Jacalin smart00915
Jacalin-like lectin domain; This entry represents a mannose-binding lectin domain with a ...
 179-313 2.23e-46

Jacalin-like lectin domain; This entry represents a mannose-binding lectin domain with a beta-prism fold consisting of three 4-stranded beta-sheets, with an internal pseudo 3-fold symmetry. Some lectins in this group stimulate distinct T- and B- cell functions, such as Jacalin, which binds to the T-antigen and acts as an agglutinin. This domain is found in 1 to 6 copies in lectins. The domain is also found in the salt-stress induced protein from rice and an animal prostatic spermine-binding protein.


:

Pssm-ID: 214909 [Multi-domain]  Cd Length: 128  Bit Score: 152.77  E-value: 2.23e-46
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145336647   179 GDYWDDGpNYDGVRKVYVTYMNTCIRSINIDYEKDGQVVTSSHGNKEGETEEFaIDYPNEFLISVEGTYDSilfpdhyVL 258
Cdd:smart00915   1 GTEWDDG-AFDGVRKIYVGQGGEGIKSIQFDYDKGGKVWGDEHGGKGGTGEEI-LLYPGEYITSVEGTYDK-------SG 71

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 145336647   259 VITSLSFKTSKGRISPTYGVVSGTKFVLESQ-GNAIVGFYGRNGGAF-DAIGVYFSP 313
Cdd:smart00915  72 VITSLTFKTNKGRTSPFGGYEGGTKFVLESKeGKKIVGFHGRSSGDGlDSLGAYFSP 128
Jacalin smart00915
Jacalin-like lectin domain; This entry represents a mannose-binding lectin domain with a ...
 34-164 4.41e-43

Jacalin-like lectin domain; This entry represents a mannose-binding lectin domain with a beta-prism fold consisting of three 4-stranded beta-sheets, with an internal pseudo 3-fold symmetry. Some lectins in this group stimulate distinct T- and B- cell functions, such as Jacalin, which binds to the T-antigen and acts as an agglutinin. This domain is found in 1 to 6 copies in lectins. The domain is also found in the salt-stress induced protein from rice and an animal prostatic spermine-binding protein.


:

Pssm-ID: 214909 [Multi-domain]  Cd Length: 128  Bit Score: 144.29  E-value: 4.41e-43
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145336647    34 GKEWDDGAgHDNVAKVYIRGGLEGIQYIKFDYVKDGQsVEGSIHGVSGsgfTQMFEIDYQNGEHIVSVDGYFDKSGVMQA 113
Cdd:smart00915   1 GTEWDDGA-FDGVRKIYVGQGGEGIKSIQFDYDKGGK-VWGDEHGGKG---GTGEEILLYPGEYITSVEGTYDKSGVITS 75

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|...
gi 145336647   114 LEFKTNR-KTSEVIGYPkSNTKFSLGGVNGKMINGFHG-SAGKALNSIGAYLT 164
Cdd:smart00915  76 LTFKTNKgRTSPFGGYE-GGTKFVLESKEGKKIVGFHGrSSGDGLDSLGAYFS 127
 
Name Accession Description Interval E-value
Jacalin smart00915
Jacalin-like lectin domain; This entry represents a mannose-binding lectin domain with a ...
 179-313 2.23e-46

Jacalin-like lectin domain; This entry represents a mannose-binding lectin domain with a beta-prism fold consisting of three 4-stranded beta-sheets, with an internal pseudo 3-fold symmetry. Some lectins in this group stimulate distinct T- and B- cell functions, such as Jacalin, which binds to the T-antigen and acts as an agglutinin. This domain is found in 1 to 6 copies in lectins. The domain is also found in the salt-stress induced protein from rice and an animal prostatic spermine-binding protein.


Pssm-ID: 214909 [Multi-domain]  Cd Length: 128  Bit Score: 152.77  E-value: 2.23e-46
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145336647   179 GDYWDDGpNYDGVRKVYVTYMNTCIRSINIDYEKDGQVVTSSHGNKEGETEEFaIDYPNEFLISVEGTYDSilfpdhyVL 258
Cdd:smart00915   1 GTEWDDG-AFDGVRKIYVGQGGEGIKSIQFDYDKGGKVWGDEHGGKGGTGEEI-LLYPGEYITSVEGTYDK-------SG 71

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 145336647   259 VITSLSFKTSKGRISPTYGVVSGTKFVLESQ-GNAIVGFYGRNGGAF-DAIGVYFSP 313
Cdd:smart00915  72 VITSLTFKTNKGRTSPFGGYEGGTKFVLESKeGKKIVGFHGRSSGDGlDSLGAYFSP 128
Jacalin pfam01419
Jacalin-like lectin domain; Proteins containing this domain are lectins. It is found in 1 to 6 ...
 179-313 1.35e-45

Jacalin-like lectin domain; Proteins containing this domain are lectins. It is found in 1 to 6 copies in these proteins. The domain is also found in the animal prostatic spermine-binding protein.


Pssm-ID: 396138 [Multi-domain]  Cd Length: 134  Bit Score: 151.28  E-value: 1.35e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145336647  179 GDYWDDGpNYDGVRKVYVTYMNTCIRSINIDYEKDGQVVTSS-HGNK-EGETEEFAIDYPNEFLISVEGTYDSILFPDhy 256
Cdd:pfam01419   1 GASWDDG-VYDGVRKVYVGQGGDGITYIKFEYVKGGGKVEGDeHGKKgLLGPEEFEIDYPDEYITSVEGTYDKVFGSD-- 77

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 145336647  257 VLVITSLSFKTSKGRISPTYGVVSGTKFVLESQGNAIVGFYGRNGGAFDAIGVYFSP 313
Cdd:pfam01419  78 SEVITSLTFKTNKGRTSPFFGTPSGTKFSLEVKGKKIVGFHGRAGNALNALGAYFAP 134
Jacalin cd09612
Jacalin-like plant lectin domain; Jacalin-like lectins are sugar-binding protein domains ...
 179-312 9.87e-44

Jacalin-like plant lectin domain; Jacalin-like lectins are sugar-binding protein domains mostly found in plants. They adopt a beta-prism topology consistent with a circularly permuted three-fold repeat of a structural motif. Proteins containing this domain may bind mono- or oligosaccharides with high specificity. The domain can occur in tandem-repeat arrangements with up to six copies, and in architectures combined with a variety of other functional domains. The family was initially named after an abundant protein found in the jackfruit seed. Jacalin specifically binds to the alpha-O-glycoside of the disaccharide Gal-beta1-3-GalNAc, and has proven useful in the study of O-linked glycoproteins. Jacalin-like lectins in this family may occur in various oligomerization states.


Pssm-ID: 187708 [Multi-domain]  Cd Length: 130  Bit Score: 146.17  E-value: 9.87e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145336647 179 GDYWDDGPNYDGVRKVYVTYMNTCIRSINIDYEKDGQ-VVTSSHGNKEGETEEFAIDYPNEFLISVEGTYDSILFPDhyv 257
Cdd:cd09612    1 GSAWDDGVFPDGLRKITVRSGENGIDSIKFEYDKDGQhVVGPWHGGGGGTPEEIVLDYPDEYITSVSGTYGPVSGSN--- 77

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 145336647 258 lVITSLSFKTSKgRISPTYGVVSGTKFVLESQGNAIVGFYGRNGGAFDAIGVYFS 312
Cdd:cd09612   78 -VITSLTFKTNK-RTYGPFGVESGTPFSLPVEGGKIVGFHGRSGDYLDAIGVYVS 130
Jacalin smart00915
Jacalin-like lectin domain; This entry represents a mannose-binding lectin domain with a ...
 34-164 4.41e-43

Jacalin-like lectin domain; This entry represents a mannose-binding lectin domain with a beta-prism fold consisting of three 4-stranded beta-sheets, with an internal pseudo 3-fold symmetry. Some lectins in this group stimulate distinct T- and B- cell functions, such as Jacalin, which binds to the T-antigen and acts as an agglutinin. This domain is found in 1 to 6 copies in lectins. The domain is also found in the salt-stress induced protein from rice and an animal prostatic spermine-binding protein.


Pssm-ID: 214909 [Multi-domain]  Cd Length: 128  Bit Score: 144.29  E-value: 4.41e-43
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145336647    34 GKEWDDGAgHDNVAKVYIRGGLEGIQYIKFDYVKDGQsVEGSIHGVSGsgfTQMFEIDYQNGEHIVSVDGYFDKSGVMQA 113
Cdd:smart00915   1 GTEWDDGA-FDGVRKIYVGQGGEGIKSIQFDYDKGGK-VWGDEHGGKG---GTGEEILLYPGEYITSVEGTYDKSGVITS 75

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|...
gi 145336647   114 LEFKTNR-KTSEVIGYPkSNTKFSLGGVNGKMINGFHG-SAGKALNSIGAYLT 164
Cdd:smart00915  76 LTFKTNKgRTSPFGGYE-GGTKFVLESKEGKKIVGFHGrSSGDGLDSLGAYFS 127
Jacalin pfam01419
Jacalin-like lectin domain; Proteins containing this domain are lectins. It is found in 1 to 6 ...
 34-164 5.56e-40

Jacalin-like lectin domain; Proteins containing this domain are lectins. It is found in 1 to 6 copies in these proteins. The domain is also found in the animal prostatic spermine-binding protein.


Pssm-ID: 396138 [Multi-domain]  Cd Length: 134  Bit Score: 136.64  E-value: 5.56e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145336647   34 GKEWDDGAgHDNVAKVYIRGGLEGIQYIKFDYVKDGQSVEGSIHGVSGSGFTQMFEIDYQNgEHIVSVDGYFDK-----S 108
Cdd:pfam01419   1 GASWDDGV-YDGVRKVYVGQGGDGITYIKFEYVKGGGKVEGDEHGKKGLLGPEEFEIDYPD-EYITSVEGTYDKvfgsdS 78

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 145336647  109 GVMQALEFKTN-RKTSEVIGYPkSNTKFSLgGVNGKMINGFHGSAGKALNSIGAYLT 164
Cdd:pfam01419  79 EVITSLTFKTNkGRTSPFFGTP-SGTKFSL-EVKGKKIVGFHGRAGNALNALGAYFA 133
Jacalin cd09612
Jacalin-like plant lectin domain; Jacalin-like lectins are sugar-binding protein domains ...
 34-164 9.48e-34

Jacalin-like plant lectin domain; Jacalin-like lectins are sugar-binding protein domains mostly found in plants. They adopt a beta-prism topology consistent with a circularly permuted three-fold repeat of a structural motif. Proteins containing this domain may bind mono- or oligosaccharides with high specificity. The domain can occur in tandem-repeat arrangements with up to six copies, and in architectures combined with a variety of other functional domains. The family was initially named after an abundant protein found in the jackfruit seed. Jacalin specifically binds to the alpha-O-glycoside of the disaccharide Gal-beta1-3-GalNAc, and has proven useful in the study of O-linked glycoproteins. Jacalin-like lectins in this family may occur in various oligomerization states.


Pssm-ID: 187708 [Multi-domain]  Cd Length: 130  Bit Score: 120.36  E-value: 9.48e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145336647  34 GKEWDDGAGHDNVAKVYIRGGLEGIQYIKFDYVKDGQSVEGSIHGVSGSGfTQMFEIDYqNGEHIVSVDGYFDK---SGV 110
Cdd:cd09612    1 GSAWDDGVFPDGLRKITVRSGENGIDSIKFEYDKDGQHVVGPWHGGGGGT-PEEIVLDY-PDEYITSVSGTYGPvsgSNV 78

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 145336647 111 MQALEFKTNRKTSEVIGYPkSNTKFSLgGVNGKMINGFHGSAGKALNSIGAYLT 164
Cdd:cd09612   79 ITSLTFKTNKRTYGPFGVE-SGTPFSL-PVEGGKIVGFHGRSGDYLDAIGVYVS 130
PLN02193 PLN02193
nitrile-specifier protein
 22-177 5.30e-26

nitrile-specifier protein


Pssm-ID: 177844 [Multi-domain]  Cd Length: 470  Bit Score: 107.35  E-value: 5.30e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145336647  22 MAQKLEAKGGKGGKEWDDGAgHDNVAKVYIRGGLEGIQYIKFDYVKDGQSVEGSIHGVSGSGFTQMFEIDYQngEHIVSV 101
Cdd:PLN02193   1 MAQKLEAKGGETGDVWDDGV-YDNVRKVYVGQGQYGIAFVKFEYVNGSQVVVGDEHGKKTELGVEEFEIDAD--DYIVYV 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145336647 102 DGYFDK-----SGVMQALEFKTNR-KTSEVIGyPKSNTKFSLGGvnGKMInGFHGSAGKALNSIGAYLTKVPPTKseLVG 175
Cdd:PLN02193  78 EGYREKvndmtSEMITFLSFKTYKgKTSHPIE-KRPGVKFVLQG--GKIV-GFHGRSTDVLHSLGAYISLPSTPK--LLG 151


                 ..
gi 145336647 176 GW 177
Cdd:PLN02193 152 KW 153
PLN02193 PLN02193
nitrile-specifier protein
 170-312 1.70e-22

nitrile-specifier protein


Pssm-ID: 177844 [Multi-domain]  Cd Length: 470  Bit Score: 97.33  E-value: 1.70e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145336647 170 KSELVGGWGGDYWDDGPnYDGVRKVYVTYMNTCIRSINIDYEKDGQVVT-SSHGNK-EGETEEFAIDyPNEFLISVEGTY 247
Cdd:PLN02193   4 KLEAKGGETGDVWDDGV-YDNVRKVYVGQGQYGIAFVKFEYVNGSQVVVgDEHGKKtELGVEEFEID-ADDYIVYVEGYR 81

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 145336647 248 DSIlfPDHYVLVITSLSFKTSKGRISPTYGVVSGTKFVLesQGNAIVGFYGRNGGAFDAIGVYFS 312
Cdd:PLN02193  82 EKV--NDMTSEMITFLSFKTYKGKTSHPIEKRPGVKFVL--QGGKIVGFHGRSTDVLHSLGAYIS 142
 
Name Accession Description Interval E-value
Jacalin smart00915
Jacalin-like lectin domain; This entry represents a mannose-binding lectin domain with a ...
 179-313 2.23e-46

Jacalin-like lectin domain; This entry represents a mannose-binding lectin domain with a beta-prism fold consisting of three 4-stranded beta-sheets, with an internal pseudo 3-fold symmetry. Some lectins in this group stimulate distinct T- and B- cell functions, such as Jacalin, which binds to the T-antigen and acts as an agglutinin. This domain is found in 1 to 6 copies in lectins. The domain is also found in the salt-stress induced protein from rice and an animal prostatic spermine-binding protein.


Pssm-ID: 214909 [Multi-domain]  Cd Length: 128  Bit Score: 152.77  E-value: 2.23e-46
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145336647   179 GDYWDDGpNYDGVRKVYVTYMNTCIRSINIDYEKDGQVVTSSHGNKEGETEEFaIDYPNEFLISVEGTYDSilfpdhyVL 258
Cdd:smart00915   1 GTEWDDG-AFDGVRKIYVGQGGEGIKSIQFDYDKGGKVWGDEHGGKGGTGEEI-LLYPGEYITSVEGTYDK-------SG 71

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 145336647   259 VITSLSFKTSKGRISPTYGVVSGTKFVLESQ-GNAIVGFYGRNGGAF-DAIGVYFSP 313
Cdd:smart00915  72 VITSLTFKTNKGRTSPFGGYEGGTKFVLESKeGKKIVGFHGRSSGDGlDSLGAYFSP 128
Jacalin pfam01419
Jacalin-like lectin domain; Proteins containing this domain are lectins. It is found in 1 to 6 ...
 179-313 1.35e-45

Jacalin-like lectin domain; Proteins containing this domain are lectins. It is found in 1 to 6 copies in these proteins. The domain is also found in the animal prostatic spermine-binding protein.


Pssm-ID: 396138 [Multi-domain]  Cd Length: 134  Bit Score: 151.28  E-value: 1.35e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145336647  179 GDYWDDGpNYDGVRKVYVTYMNTCIRSINIDYEKDGQVVTSS-HGNK-EGETEEFAIDYPNEFLISVEGTYDSILFPDhy 256
Cdd:pfam01419   1 GASWDDG-VYDGVRKVYVGQGGDGITYIKFEYVKGGGKVEGDeHGKKgLLGPEEFEIDYPDEYITSVEGTYDKVFGSD-- 77

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 145336647  257 VLVITSLSFKTSKGRISPTYGVVSGTKFVLESQGNAIVGFYGRNGGAFDAIGVYFSP 313
Cdd:pfam01419  78 SEVITSLTFKTNKGRTSPFFGTPSGTKFSLEVKGKKIVGFHGRAGNALNALGAYFAP 134
Jacalin cd09612
Jacalin-like plant lectin domain; Jacalin-like lectins are sugar-binding protein domains ...
 179-312 9.87e-44

Jacalin-like plant lectin domain; Jacalin-like lectins are sugar-binding protein domains mostly found in plants. They adopt a beta-prism topology consistent with a circularly permuted three-fold repeat of a structural motif. Proteins containing this domain may bind mono- or oligosaccharides with high specificity. The domain can occur in tandem-repeat arrangements with up to six copies, and in architectures combined with a variety of other functional domains. The family was initially named after an abundant protein found in the jackfruit seed. Jacalin specifically binds to the alpha-O-glycoside of the disaccharide Gal-beta1-3-GalNAc, and has proven useful in the study of O-linked glycoproteins. Jacalin-like lectins in this family may occur in various oligomerization states.


Pssm-ID: 187708 [Multi-domain]  Cd Length: 130  Bit Score: 146.17  E-value: 9.87e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145336647 179 GDYWDDGPNYDGVRKVYVTYMNTCIRSINIDYEKDGQ-VVTSSHGNKEGETEEFAIDYPNEFLISVEGTYDSILFPDhyv 257
Cdd:cd09612    1 GSAWDDGVFPDGLRKITVRSGENGIDSIKFEYDKDGQhVVGPWHGGGGGTPEEIVLDYPDEYITSVSGTYGPVSGSN--- 77

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 145336647 258 lVITSLSFKTSKgRISPTYGVVSGTKFVLESQGNAIVGFYGRNGGAFDAIGVYFS 312
Cdd:cd09612   78 -VITSLTFKTNK-RTYGPFGVESGTPFSLPVEGGKIVGFHGRSGDYLDAIGVYVS 130
Jacalin smart00915
Jacalin-like lectin domain; This entry represents a mannose-binding lectin domain with a ...
 34-164 4.41e-43

Jacalin-like lectin domain; This entry represents a mannose-binding lectin domain with a beta-prism fold consisting of three 4-stranded beta-sheets, with an internal pseudo 3-fold symmetry. Some lectins in this group stimulate distinct T- and B- cell functions, such as Jacalin, which binds to the T-antigen and acts as an agglutinin. This domain is found in 1 to 6 copies in lectins. The domain is also found in the salt-stress induced protein from rice and an animal prostatic spermine-binding protein.


Pssm-ID: 214909 [Multi-domain]  Cd Length: 128  Bit Score: 144.29  E-value: 4.41e-43
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145336647    34 GKEWDDGAgHDNVAKVYIRGGLEGIQYIKFDYVKDGQsVEGSIHGVSGsgfTQMFEIDYQNGEHIVSVDGYFDKSGVMQA 113
Cdd:smart00915   1 GTEWDDGA-FDGVRKIYVGQGGEGIKSIQFDYDKGGK-VWGDEHGGKG---GTGEEILLYPGEYITSVEGTYDKSGVITS 75

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|...
gi 145336647   114 LEFKTNR-KTSEVIGYPkSNTKFSLGGVNGKMINGFHG-SAGKALNSIGAYLT 164
Cdd:smart00915  76 LTFKTNKgRTSPFGGYE-GGTKFVLESKEGKKIVGFHGrSSGDGLDSLGAYFS 127
Jacalin pfam01419
Jacalin-like lectin domain; Proteins containing this domain are lectins. It is found in 1 to 6 ...
 34-164 5.56e-40

Jacalin-like lectin domain; Proteins containing this domain are lectins. It is found in 1 to 6 copies in these proteins. The domain is also found in the animal prostatic spermine-binding protein.


Pssm-ID: 396138 [Multi-domain]  Cd Length: 134  Bit Score: 136.64  E-value: 5.56e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145336647   34 GKEWDDGAgHDNVAKVYIRGGLEGIQYIKFDYVKDGQSVEGSIHGVSGSGFTQMFEIDYQNgEHIVSVDGYFDK-----S 108
Cdd:pfam01419   1 GASWDDGV-YDGVRKVYVGQGGDGITYIKFEYVKGGGKVEGDEHGKKGLLGPEEFEIDYPD-EYITSVEGTYDKvfgsdS 78

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 145336647  109 GVMQALEFKTN-RKTSEVIGYPkSNTKFSLgGVNGKMINGFHGSAGKALNSIGAYLT 164
Cdd:pfam01419  79 EVITSLTFKTNkGRTSPFFGTP-SGTKFSL-EVKGKKIVGFHGRAGNALNALGAYFA 133
Jacalin cd09612
Jacalin-like plant lectin domain; Jacalin-like lectins are sugar-binding protein domains ...
 34-164 9.48e-34

Jacalin-like plant lectin domain; Jacalin-like lectins are sugar-binding protein domains mostly found in plants. They adopt a beta-prism topology consistent with a circularly permuted three-fold repeat of a structural motif. Proteins containing this domain may bind mono- or oligosaccharides with high specificity. The domain can occur in tandem-repeat arrangements with up to six copies, and in architectures combined with a variety of other functional domains. The family was initially named after an abundant protein found in the jackfruit seed. Jacalin specifically binds to the alpha-O-glycoside of the disaccharide Gal-beta1-3-GalNAc, and has proven useful in the study of O-linked glycoproteins. Jacalin-like lectins in this family may occur in various oligomerization states.


Pssm-ID: 187708 [Multi-domain]  Cd Length: 130  Bit Score: 120.36  E-value: 9.48e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145336647  34 GKEWDDGAGHDNVAKVYIRGGLEGIQYIKFDYVKDGQSVEGSIHGVSGSGfTQMFEIDYqNGEHIVSVDGYFDK---SGV 110
Cdd:cd09612    1 GSAWDDGVFPDGLRKITVRSGENGIDSIKFEYDKDGQHVVGPWHGGGGGT-PEEIVLDY-PDEYITSVSGTYGPvsgSNV 78

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 145336647 111 MQALEFKTNRKTSEVIGYPkSNTKFSLgGVNGKMINGFHGSAGKALNSIGAYLT 164
Cdd:cd09612   79 ITSLTFKTNKRTYGPFGVE-SGTPFSL-PVEGGKIVGFHGRSGDYLDAIGVYVS 130
PLN02193 PLN02193
nitrile-specifier protein
 22-177 5.30e-26

nitrile-specifier protein


Pssm-ID: 177844 [Multi-domain]  Cd Length: 470  Bit Score: 107.35  E-value: 5.30e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145336647  22 MAQKLEAKGGKGGKEWDDGAgHDNVAKVYIRGGLEGIQYIKFDYVKDGQSVEGSIHGVSGSGFTQMFEIDYQngEHIVSV 101
Cdd:PLN02193   1 MAQKLEAKGGETGDVWDDGV-YDNVRKVYVGQGQYGIAFVKFEYVNGSQVVVGDEHGKKTELGVEEFEIDAD--DYIVYV 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145336647 102 DGYFDK-----SGVMQALEFKTNR-KTSEVIGyPKSNTKFSLGGvnGKMInGFHGSAGKALNSIGAYLTKVPPTKseLVG 175
Cdd:PLN02193  78 EGYREKvndmtSEMITFLSFKTYKgKTSHPIE-KRPGVKFVLQG--GKIV-GFHGRSTDVLHSLGAYISLPSTPK--LLG 151


                 ..
gi 145336647 176 GW 177
Cdd:PLN02193 152 KW 153
PLN02193 PLN02193
nitrile-specifier protein
 170-312 1.70e-22

nitrile-specifier protein


Pssm-ID: 177844 [Multi-domain]  Cd Length: 470  Bit Score: 97.33  E-value: 1.70e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145336647 170 KSELVGGWGGDYWDDGPnYDGVRKVYVTYMNTCIRSINIDYEKDGQVVT-SSHGNK-EGETEEFAIDyPNEFLISVEGTY 247
Cdd:PLN02193   4 KLEAKGGETGDVWDDGV-YDNVRKVYVGQGQYGIAFVKFEYVNGSQVVVgDEHGKKtELGVEEFEID-ADDYIVYVEGYR 81

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 145336647 248 DSIlfPDHYVLVITSLSFKTSKGRISPTYGVVSGTKFVLesQGNAIVGFYGRNGGAFDAIGVYFS 312
Cdd:PLN02193  82 EKV--NDMTSEMITFLSFKTYKGKTSHPIEKRPGVKFVL--QGGKIVGFHGRSTDVLHSLGAYIS 142
griffithsin_like cd09614
Jacalin-like lectin domain of griffithsin and related proteins; Griffithsin is a lectin ...
 31-165 2.98e-05

Jacalin-like lectin domain of griffithsin and related proteins; Griffithsin is a lectin isolated from a red alga, which has shown potential as an inhibitor of viral entry, exhibiting antiviral activity against HIV and SARS. The biological functions of griffithsin and griffithsin-like proteins with respect to their source organisms are not known.


Pssm-ID: 187710  Cd Length: 128  Bit Score: 42.77  E-value: 2.98e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145336647  31 GKGGKEWDDGAGHDNVAkVYIRGGLEgIQYIKFDYVKDGQSVEGSiHGVSGSGFTQMFEIdyQNGEHIVSVDGyfdKSG- 109
Cdd:cd09614    1 GFGGSPGSDFDILTVSA-IQLRSGSY-VDQIITDYQDLNGTQNFH-HGGGGGNLSPTLNF--SSGEYITEVTG---RSGd 72

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 145336647 110 VMQALEFKTNRKTSEVIGYPKSNTKFSLGGVNGKMINGFHGSAGKALNSIGAYLTK 165
Cdd:cd09614   73 RVDQVQFTTNYGGRTLPGGGGGGSAFTWTVPDNQKVIGFAGRSGSYLDQLQVYYLS 128
Jacalin_ZG16_like cd09611
Jacalin-like lectin domain of the zymogen granule protein 16 and related proteins; ZG16p is a ...
 175-312 2.12e-04

Jacalin-like lectin domain of the zymogen granule protein 16 and related proteins; ZG16p is a conserved secreted vertebrate protein with tissue-specific expression profiles, which might play a role in glycoprotein secretion, perhaps as a linker protein that participates in the formation and/or transport of the zymogen granule. Its paralog ZG16b (PAUF) has been associated with roles in gene regulation and cancer. This domain family also contains mammalian proteins labelled as prostatic spermine-binding protein (SBP) and salivary-gland specific secreted proteins.


Pssm-ID: 187707 [Multi-domain]  Cd Length: 128  Bit Score: 40.38  E-value: 2.12e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145336647 175 GGWGGDYWDDGPNYDG-VRKVYVTYMNTCIRSINIDYekdGQVVTSSHGNKEGETEEFAIDyPNEFLISVEGTYDSIlfp 253
Cdd:cd09611    1 GSGGGKYFSDVGEGGGpITGIRVSVGNNYIKGIQVRY---GSNWSDVYGGRGGNEQEIVLE-PGESITKVSGSYKIY--- 73

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 145336647 254 dhyvlvITSLSFKTSKGRiSPTYGVVSGTKFVLE--SQGNAIVGFYGR-NGGAFDAIGVYFS 312
Cdd:cd09611   74 ------LHGLVFTTNKGR-YLSFGKLRGRSFNATppPSNYVLRGISGRyGGLGIKSIGFHWG 128
Jacalin_like cd09302
Jacalin-like lectin domain; Jacalin-like lectins are sugar-binding protein domains mostly ...
 179-312 3.32e-03

Jacalin-like lectin domain; Jacalin-like lectins are sugar-binding protein domains mostly found in plants. They adopt a beta-prism topology consistent with a circularly permuted three-fold repeat of a structural motif. Proteins containing this domain may bind mono- or oligosaccharides with high specificity. The domain can occur in tandem-repeat arrangements with up to six copies, and in architectures combined with a variety of other functional domains. Taxonomic distribution is not restricted to plants, the domain is also found in various mammalian proteins, for example.


Pssm-ID: 187706  Cd Length: 128  Bit Score: 37.00  E-value: 3.32e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145336647 179 GDYWDDGPNYD-GVRKVYVtYMNTCIRSINIDYekdGQVVTSSHGNKEGETEEFAIDYPNEFLISVEGTYDSilfpDHYV 257
Cdd:cd09302    1 GKPFSDTGGDGaRLTEIRV-RSGGAVDAIRVVL---RDYTDGRHGGNGGPNTSSVFLDPGEYITITSVSSGD----NGGG 72

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 145336647 258 LVITSLSFKTSKGRiSPTYGVVS---GTKFVLESqGNAIVGFYGRNGGAFDAIGVYFS 312
Cdd:cd09302   73 TRIDAIQFTTNKGR-SGTYGTTSgalGTEFTVPV-GGEIVGIYGRAGDDVDAFGFILS 128
griffithsin_like cd09614
Jacalin-like lectin domain of griffithsin and related proteins; Griffithsin is a lectin ...
 205-311 3.74e-03

Jacalin-like lectin domain of griffithsin and related proteins; Griffithsin is a lectin isolated from a red alga, which has shown potential as an inhibitor of viral entry, exhibiting antiviral activity against HIV and SARS. The biological functions of griffithsin and griffithsin-like proteins with respect to their source organisms are not known.


Pssm-ID: 187710  Cd Length: 128  Bit Score: 36.99  E-value: 3.74e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145336647 205 SINIDYEKDGQVVTSSHGNKEGETEEFAIDYPNEFLISVEGTYDSilfpdhyvlVITSLSFKTSKGRISPTYGVVSGTKF 284
Cdd:cd09614   28 QIITDYQDLNGTQNFHHGGGGGNLSPTLNFSSGEYITEVTGRSGD---------RVDQVQFTTNYGGRTLPGGGGGGSAF 98

                         90       100
                 ....*....|....*....|....*...
gi 145336647 285 VLESQGNAIV-GFYGRNGGAFDAIGVYF 311
Cdd:cd09614   99 TWTVPDNQKViGFAGRSGSYLDQLQVYY 126
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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