|
Name |
Accession |
Description |
Interval |
E-value |
| PLN02900 |
PLN02900 |
alanyl-tRNA synthetase |
49-1000 |
0e+00 |
|
alanyl-tRNA synthetase
Pssm-ID: 215487 [Multi-domain] Cd Length: 936 Bit Score: 1664.77 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 49 MPGSEPSETQWPAKRVRDTYVDFFRGKGHKFWPSSPVVPHNDPTLLFANAGMNQYKPIFLGTADPNTELSKLSRACNTQK 128
Cdd:PLN02900 1 MPEDDAPEKEWPGDRIRRTFLSFFESKGHTFLPSSPLVPVDDPTLLFTNAGMNQFKPIFLGTADPNTPLRKLPRATNTQK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 129 CIRAGGKHNDLDDVGKDTYHHTFFEMLGNWSFGDYFKKEAIEWAWELLTKVYGLPTDRIYATYFGGDEKagLQPDNEARD 208
Cdd:PLN02900 81 CIRAGGKHNDLDDVGKDTYHHTFFEMLGNWSFGDYFKKEAIGWAWELLTKVYGLPADRLYATYFGGDEK--QAPDDEARA 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 209 IWLKVLPSGRVLPFGCKDNFWEMGDTGPCGPCTEIHYDRIGNRDAASLVNNDDPTCLEIWNLVFIQFNRESDGSLKPLPA 288
Cdd:PLN02900 159 IWLDYLPEERVLPFGCKDNFWEMGDTGPCGPCSEIHYDRIGERDAADLVNNDDPRFIEIWNLVFIQFNREADGSLKPLPA 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 289 KHVDTGMGFERLTSVLQNKMSNYDTDVFMPIFDDIQKATGARPYSGKVGPEDVDRVDMAYRVVADHIRTLSFAIADGSRP 368
Cdd:PLN02900 239 KHVDTGMGLERLASILQNKPSNYDTDLFMPIFDAIQEATGARPYAGKVGAEDDDRVDMAYRVVADHIRTLSFAIADGVVP 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 369 GNEGREYVLRRILRRAVRYGKEILKAEEGFFNGLVSSVIRVMGDVFTELKEHEKKITDIIKEEEASFCKTLAKGIEKFRK 448
Cdd:PLN02900 319 SNEGRGYVLRRLLRRAVRYGRLLLGAEEGFFPALVEVVVELSGDVFPEVKKNEKRITEIIAEEELSFGKTLEKGIEKFKK 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 449 AGQAVQ---GNTLSGDDAFILWDTYGFPLDLTQLMAEERGLLVDVDGFNKAMEEARERSRSAQNKQAGGAIVMDADATST 525
Cdd:PLN02900 399 ALAAAKangGPVLSGKDAFLLYDTYGFPVDLTELMAEERGVTVDMEGFEAAMEEARERSRAAHLKAGGGAIELAAEATSW 478
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 526 LHKAGVSATDDSFKYIWFQDHESELKAIYTGSTFLESSAASDNVGLVLGSTSFYAEQGGQIFDTGLIEGSFG-TFNVCNV 604
Cdd:PLN02900 479 LQKQGVAATDDFLKYDWLSDHEAVVKAILTGGGFVESVSEGDEVGIVLDKTSFYAESGGQIGDTGVLEGSGGaVVEVSDV 558
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 605 QIFGGFVLHIGYLSKetGEVSVGDKVICKVDYERRKLIAPNHTCTHMLNYALKEVLGDHIDQKGSIVLPEKLRFDFSHGK 684
Cdd:PLN02900 559 QKAGGFVLHIGTVTE--GSVSVGDAVTCKVDYDRRRRIAPNHTATHLLNSALKEVLGDHVDQKGSLVAFEKLRFDFSHGK 636
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 685 PVDPEDLRRIESIVNKQIKDELDVFSKEAVLSEAKRIKGLRAVFGEVYPDPVRVVSIGRKvedlladpennewslLSSEF 764
Cdd:PLN02900 637 PMTPEELREVESLVNEWIGDALPVEAKEMPLADAKRINGLRAVFGEKYPDPVRVVSVGGV---------------YSMEL 701
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 765 CGGTHITNTREAKAFALLSEEGIAKGIRRVTAVTTECAFDALNAASLLEREVEDASRAEGSALEKKVSALKSRVDAAIIP 844
Cdd:PLN02900 702 CGGTHVSNTAEAEAFKLLSEEGIAKGIRRITAVTGGAAVEAINAADSLERELDSALKVEGSDLEKKVASLKSRVDAAVIP 781
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 845 AAKKADIRTKIASLQNEVRKAQKKIAEQNLKKSVKLATEAAESAASDGKTFCIIQLDVGLDAAAVREAVSKVMEKK-GMS 923
Cdd:PLN02900 782 AAKKEEIRARVSALQKELRAAQKEAAALRAKLAVAKATELASKALSAGKSVLVARLDVGVDAAALKEAAEKVIAKLgDPA 861
|
890 900 910 920 930 940 950
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 30694735 924 IMVFSTDESTNKAVVCAGVPEKSDQfKPLDVTEWLtTALGPLKGRCGKGKGGLASGQGTDASQVQAALDMASSFASM 1000
Cdd:PLN02900 862 AVVLSSDEEKGKVSLVAAVPPGVVK-KGLKAGKWL-GAIAKLCGGGGGGKPGFAQGQGRDAEKLDAALEKARAFAVA 936
|
|
| AlaS |
COG0013 |
Alanyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Alanyl-tRNA ... |
64-942 |
0e+00 |
|
Alanyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Alanyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439784 [Multi-domain] Cd Length: 880 Bit Score: 1031.93 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 64 VRDTYVDFFRGKGHKFWPSSPVVPHNDPTLLFANAGMNQYKPIFLGTADPntelsKLSRACNTQKCIRAGGKHNDLDDVG 143
Cdd:COG0013 7 IRQKFLDFFESKGHTIVPSSSLVPKNDPTLLFTNAGMVQFKPYFLGQEKP-----PYPRATTSQKCVRTGGKHNDLENVG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 144 KDTYHHTFFEMLGNWSFGDYFKKEAIEWAWELLTKVYGLPTDRIYATYFGGDEkaglqpdnEARDIWLKV--LPSGRVLP 221
Cdd:COG0013 82 YTARHHTFFEMLGNFSFGDYFKEEAIAWAWELLTEVLGLPKERLWVTVYEDDD--------EAYDIWKKEigVPEERIIR 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 222 FGCKDNFWEMGDTGPCGPCTEIHYDR---IGNrDAASLVNNDDPTCLEIWNLVFIQFNRESDGSLKPLPAKHVDTGMGFE 298
Cdd:COG0013 154 LGKKDNFWEMGDTGPCGPCSEIFYDRgpeYGG-GPPGSPGEDGDRYIEIWNLVFMQFNRDEDGTLTPLPKKNIDTGMGLE 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 299 RLTSVLQNKMSNYDTDVFMPIFDDIQKATGaRPYsGKVGPEDVdrvdmAYRVVADHIRTLSFAIADGSRPGNEGREYVLR 378
Cdd:COG0013 233 RIAAVLQGVHSNYETDLFRPLIEAAAELTG-VKY-GADEEDDV-----SLRVIADHIRAVAFLIADGVLPSNEGRGYVLR 305
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 379 RILRRAVRYGKeILKAEEGFFNGLVSSVIRVMGDVFTELKEHEKKITDIIKEEEASFCKTLAKGIEKFRKA---GQAVQG 455
Cdd:COG0013 306 RILRRAVRHGR-LLGIKEPFLYKLVPVVVEEMGDAYPELKEKQELIEKVLKAEEERFLRTLERGLKLLDEAiakLKAAGG 384
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 456 NTLSGDDAFILWDTYGFPLDLTQLMAEERGLLVDVDGFNKAMEEARERSRSAQNKQAGGAIvmDADATSTLHKAGvsATD 535
Cdd:COG0013 385 KVLSGEDAFKLYDTYGFPLDLTEEIARERGLTVDEEGFEAAMEEQRERARAAAKFSGDAAV--DGVWRELLEEGG--PTE 460
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 536 ----DSFKyiwfqdHESELKAIYTGSTFLESSAASDNVGLVLGSTSFYAEQGGQIFDTGLIEGSFGTFNVCNVQ-IFGGF 610
Cdd:COG0013 461 fvgyDTLE------AEAKVLALVKDGELVDSAKAGEEVEVVLDRTPFYAESGGQVGDTGTIEGDGGVFEVTDTQkPPGGL 534
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 611 VLHIGYLskETGEVSVGDKVICKVDYERRKLIAPNHTCTHMLNYALKEVLGDHIDQKGSIVLPEKLRFDFSHGKPVDPED 690
Cdd:COG0013 535 IVHIGKV--EEGELKVGDTVTAQVDAERRRAIARNHSATHLLHAALREVLGEHVTQAGSLVAPDRLRFDFSHFEALTPEE 612
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 691 LRRIESIVNKQIKDELDVFSKEAVLSEAKRiKGLRAVFGEVYPDPVRVVSIGrkvedlladpennEWSLlssEFCGGTHI 770
Cdd:COG0013 613 LAEIEDLVNEKIRENLPVETREMPLDEAKA-LGAMALFGEKYGDEVRVVSIG-------------DFSR---ELCGGTHV 675
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 771 TNTREAKAFALLSEEGIAKGIRRVTAVTTECAFDALNAaslLEREVEDASraegsalekkvSALKSRVDaaiipaakkaD 850
Cdd:COG0013 676 SRTGDIGLFKIVSESSVAAGVRRIEAVTGEAALEYLRE---QEALLKELA-----------ELLKAPPE----------E 731
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 851 IRTKIASLQNEVRKAQKKIAEQNLKK-SVKLATEAAESAASDGKTFCIIQLDvGLDAAAVREAVSKVMEKKGMSIMVFST 929
Cdd:COG0013 732 LPERVEALLEELKELEKELEQLKAKLaSAAADDLLAQAEEIGGVKVLAARVE-GVDAKDLRDLADDLKDKLGSGVVVLAS 810
|
890
....*....|...
gi 30694735 930 DEStNKAVVCAGV 942
Cdd:COG0013 811 VAD-GKVSLVAGV 822
|
|
| tRNA-synt_2c |
pfam01411 |
tRNA synthetases class II (A); Other tRNA synthetase sub-families are too dissimilar to be ... |
64-638 |
0e+00 |
|
tRNA synthetases class II (A); Other tRNA synthetase sub-families are too dissimilar to be included. This family includes only alanyl-tRNA synthetases.
Pssm-ID: 279719 [Multi-domain] Cd Length: 548 Bit Score: 833.46 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 64 VRDTYVDFFRGKGHKFWPSSPVVPHNDPTLLFANAGMNQYKPIFLGTADPntelSKLSRACNTQKCIRAGgkhnDLDDVG 143
Cdd:pfam01411 2 IRQTFLDFFEKKGHTRVPSSPVVPRNDPTLLFTNAGMNQFKPIFLGGVAK----PPYNRATNSQKCIRAG----DLENVG 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 144 KDTYHHTFFEMLGNWSFGDYFKKEAIEWAWELLTKVYGLPTDRIYATYFGGDEkaglqpdnEARDIWLKV--LPSGRVLP 221
Cdd:pfam01411 74 RTGRHHTFFEMLGNFSFGDYFKEEAIEYAWELLTKELGLPPERLYVTVFEWDD--------EAGPIWEKIvgGPEERILR 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 222 FGCKDNFWEMGDTGPCGPCTEIHYDR---IGNRDAASLVNNDDPTCLEIWNLVFIQFNRESDGSLKPLPAKHVDTGMGFE 298
Cdd:pfam01411 146 FGDKDNFWEMGDTGPCGPCSEIDYDRgeeIGGWDSGGTPTADDDRFLEIWNLVFMQFNRENDGTLKPLPKKSIDTGMGLE 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 299 RLTSVLQNKMSNYDTDVFMPIFDDIQKATGARPYSgkvgpedVDRVDMAYRVVADHIRTLSFAIADGSRPGNEGREYVLR 378
Cdd:pfam01411 226 RLVAVLQDVRSNYDTDVFIPVIELIEEISGARYYT-------VDETDEAYRVIADHTRALTFALADGVVPSNEGRGYVLR 298
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 379 RILRRAVRYGKEiLKAEEGFFNGLVSSVIRVMGDVFTELKEHEKKITDIIKEEEASFCKTLAKGIEKFRKAGQAV--QGN 456
Cdd:pfam01411 299 RILRRAVRHAKK-LGLKEPFLYDLVPTVVEVLGDAYPELKEDEDFIQEILELEEERFAKTLERGLRLLERLIAKLkkGKK 377
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 457 TLSGDDAFILWDTYGFPLDLTQLMAEERGLLVDVDGFNKAMEEARERSRsaQNKQAGGAiVMDADATSTLHkagvsATDD 536
Cdd:pfam01411 378 TLPGEDAFKLYDTYGFPVDLTKEIAEERGLKVDMPGFEYAMVEQRERSK--QAVKEKGE-KLDVSALKELP-----ATTE 449
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 537 SFKYIWFQDhESELKAIYTGSTFLESSAASDNVGLVLGSTSFYAEQGGQIFDTGLIEGSFGTFNVCNVQIFGGFVLHIGY 616
Cdd:pfam01411 450 FLGYDDLES-EAKILALPKDGEFVAEVLAGQEGGVILDRTPFYAESGGQIGDTGYIIGDGGEFRVTDVQKYGGVVVHKGK 528
|
570 580
....*....|....*....|..
gi 30694735 617 LskETGEVSVGDKVICKVDYER 638
Cdd:pfam01411 529 L--ESGKLKVGDKVIAVIDEDR 548
|
|
| alaS |
TIGR00344 |
alanine--tRNA ligase; The model describes alanine--tRNA ligase. This enzyme catalyzes the ... |
64-958 |
0e+00 |
|
alanine--tRNA ligase; The model describes alanine--tRNA ligase. This enzyme catalyzes the reaction (tRNAala + L-alanine + ATP = L-alanyl-tRNAala + pyrophosphate + AMP). [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 273026 [Multi-domain] Cd Length: 845 Bit Score: 810.07 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 64 VRDTYVDFFRGKGHKFWPSSPVVPHNDPTLLFANAGMNQYKPIFLGTADPNTelsklSRACNTQKCIRAggkhNDLDDVG 143
Cdd:TIGR00344 2 IRQTFLDFFKEKGHQVIPSAPLVPRNDPTLLLTNAGMAQFKPIFTGIVKPPS-----NRLTNAQPCIRL----NDLENVG 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 144 KDTYHHTFFEMLGNWSFGDYFKKEAIEWAWELLTKVYGLPTDRIYATYFGGDEKAGLQPDNeardiwlKVLPSGRVLPFG 223
Cdd:TIGR00344 73 RTARHHTLFEMLGNFSFGDYFKEEAIAFAWELLTEVLGLDKERLYVTVYEDDEEAYKIWEK-------IGIPADRIIKCD 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 224 CKDNFWEMGDtGPCGPCTEIHYDRIGNRDAASLVNNDDptCLEIWNLVFIQFNRESDGSLKPLPAKHVDTGMGFERLTSV 303
Cdd:TIGR00344 146 AKDNFWDMGD-GPCGPCTEIYYDFVGGKPGEPLEENDR--YLEVWNLVFMQFNRDPDGNYTPLPKKNIDTGMGLERFVAV 222
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 304 LQNKMSNYDTDVFMPIFDDIQKATGARPYSGKVGPEDVDRVD--MAYRVVADHIRTLSFAIADGSRPGNEGREYVLRRIL 381
Cdd:TIGR00344 223 LQGVPTNYDTDIFLPLIEKIEEITGVKYDSNNAGIMDEKRVEdlRSLRVIADHTRAIAFMLADGVVPSNEGRGYVLRRLI 302
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 382 RRAVRYGKEiLKAEEGFFNGLVSSVIRVMGDVFTELKEHEKKITDIIKEEEASFCKTLAKGIEKFRKAGQAVQGNTLSGD 461
Cdd:TIGR00344 303 RRALRHGKK-LGLKEAFLYKLVPTLIEVLGDYYPELKEKQEFVEQILELEEERFAKTLERGLRLFEKLLKKTGKKELDGE 381
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 462 DAFILWDTYGFPLDLTQLMAEERGLLVDVDGFNKAMEEARERSRSAQNKQAGGAIVMDADATSTLhkagvsatddsFKYi 541
Cdd:TIGR00344 382 DAFKLYDTYGFPVELTKEIAEERGLTVDMPGFEALMAEQRERSKQNSQFQEQEIALVNVYPATEF-----------LGY- 449
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 542 wfQDHESELK--AIYTGSTFLESSAASDNVGLVLGSTSFYAEQGGQIFDTGLIEGSFGTFNVCNVQIFGGFVLHIGYLsk 619
Cdd:TIGR00344 450 --DDLEFEAKviGLFDDGYLVEQALAGQSVYVILDQTPFYAESGGQIGDTGYLIANDGKFRVVDVQKPNGVVFHFGEV-- 525
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 620 ETGEVSVGDKVICKVDYERRKLIAPNHTCTHMLNYALKEVLGDHIDQKGSIVLPEKLRFDFSHGKPVDPEDLRRIESIVN 699
Cdd:TIGR00344 526 EGGSLKVGDKVIAVIDEKRRFRIMRNHSATHLLHAALQKVLGNHVWQAGSLVSFKKLRFDFSHFRALTREELEEIEDLAN 605
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 700 KQIKDELDVFSKEAVLSEAKRIKGLRAvFGEVYP--DPVRVVSIGRkvedlladpennewslLSSEFCGGTHITNTREAK 777
Cdd:TIGR00344 606 EQILANIPIKVIFMDLDEAKRKGAFAL-FGEKYVpgEKVRVVSVGD----------------FSVELCGGTHVRNTGEIG 668
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 778 AFALLSEEGIAKGIRRVTAVTTECAFDALNAASLLEREVEDASRAEGSALEKKVSALKsrvdaaiipaakkadirTKIAS 857
Cdd:TIGR00344 669 LFKIVKESGIAAGVRRIEAVTGEAAIEYLNEQEDKLKELADILKVTPNELPKKVERFF-----------------EEWKA 731
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 858 LQNEVRKAQKKIAEQnlkksvKLATEAAESAASDGKTFCIIQLDvGLDAAAVREAVSKVMEKKGMSIMVFSTDESTNKAV 937
Cdd:TIGR00344 732 LQKELESLKLKIADQ------KIDELKDKAETINGVKVLVEVVD-AKDMKSLKTMADRLKSKLGSAIYVLASFAEGKVKL 804
|
890 900
....*....|....*....|.
gi 30694735 938 VCaGVPEKSDQfKPLDVTEWL 958
Cdd:TIGR00344 805 VC-GVSNDVLT-KKIKAGELI 823
|
|
| AlaRS_core |
cd00673 |
Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is ... |
61-307 |
9.02e-139 |
|
Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent formation of the enzyme bound aminoacyl-adenylate. Class II assignment is based upon its predicted structure and the presence of three characteristic sequence motifs.
Pssm-ID: 238360 [Multi-domain] Cd Length: 232 Bit Score: 415.22 E-value: 9.02e-139
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 61 AKRVRDTYVDFFRGKGHKFWPSSPVVPHNDPTLLFANAGMNQYKPIFLGTADPNTelsklSRACNTQKCIRAGGKHNdld 140
Cdd:cd00673 1 ASEIRETFLSFFEKKGHTRVPSSPVVPRDDPTLLFTNAGMNQFKPIFLGEVPPPA-----NRLVNSQKCIRAGDIDN--- 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 141 dVGKDTYHHTFFEMLGNWSFGDYFKKEAIEWAWELLTKVYGLPTDRIYATYFGGDEKAglqpdnEARDIWLKVLPSGRVL 220
Cdd:cd00673 73 -VGKTGRHHTFFEMLGNFSFGDYFKEEAIAFAWELLTEVLGLPKDRLYVSVFEGDDEE------EAIWWWKIGLPGIRIE 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 221 PFGCKDNFWEMGDTGPCGPCTEIHYDRIGNRDAASLVNNDDPTCLEIWNLVFIQFNRESDGSLKPLPAKHVDTGMGFERL 300
Cdd:cd00673 146 RIGFKDNFWEMGGNGPCGPCSEIFYDRGEERDAASLPNEDDDRYLEIWNLVFMQYNRDADGTYRPLPKKIVDTGMGLERL 225
|
....*..
gi 30694735 301 TSVLQNK 307
Cdd:cd00673 226 VWVLQGV 232
|
|
| tRNA_SAD |
smart00863 |
Threonyl and Alanyl tRNA synthetase second additional domain; The catalytically active form of ... |
736-794 |
6.69e-13 |
|
Threonyl and Alanyl tRNA synthetase second additional domain; The catalytically active form of threonyl/alanyl tRNA synthetase is a dimer. Within the tRNA synthetase class II dimer, the bound tRNA interacts with both monomers making specific interactions with the catalytic domain, the C-terminal domain, and this SAD domain (the second additional domain). The second additional domain is comprised of a pair of perpendicularly orientated antiparallel beta sheets, of four and three strands, respectively, that surround a central alpha helix that forms the core of the domain.
Pssm-ID: 197931 [Multi-domain] Cd Length: 43 Bit Score: 63.56 E-value: 6.69e-13
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 30694735 736 VRVVSIGRkvedlladpennewslLSSEFCGGTHITNTREAKAFALLSEEGIAKGIRRV 794
Cdd:smart00863 1 VRVVSIGD----------------FSVELCGGTHVPNTGEIGAFKILSVSGAYWGLQRI 43
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PLN02900 |
PLN02900 |
alanyl-tRNA synthetase |
49-1000 |
0e+00 |
|
alanyl-tRNA synthetase
Pssm-ID: 215487 [Multi-domain] Cd Length: 936 Bit Score: 1664.77 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 49 MPGSEPSETQWPAKRVRDTYVDFFRGKGHKFWPSSPVVPHNDPTLLFANAGMNQYKPIFLGTADPNTELSKLSRACNTQK 128
Cdd:PLN02900 1 MPEDDAPEKEWPGDRIRRTFLSFFESKGHTFLPSSPLVPVDDPTLLFTNAGMNQFKPIFLGTADPNTPLRKLPRATNTQK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 129 CIRAGGKHNDLDDVGKDTYHHTFFEMLGNWSFGDYFKKEAIEWAWELLTKVYGLPTDRIYATYFGGDEKagLQPDNEARD 208
Cdd:PLN02900 81 CIRAGGKHNDLDDVGKDTYHHTFFEMLGNWSFGDYFKKEAIGWAWELLTKVYGLPADRLYATYFGGDEK--QAPDDEARA 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 209 IWLKVLPSGRVLPFGCKDNFWEMGDTGPCGPCTEIHYDRIGNRDAASLVNNDDPTCLEIWNLVFIQFNRESDGSLKPLPA 288
Cdd:PLN02900 159 IWLDYLPEERVLPFGCKDNFWEMGDTGPCGPCSEIHYDRIGERDAADLVNNDDPRFIEIWNLVFIQFNREADGSLKPLPA 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 289 KHVDTGMGFERLTSVLQNKMSNYDTDVFMPIFDDIQKATGARPYSGKVGPEDVDRVDMAYRVVADHIRTLSFAIADGSRP 368
Cdd:PLN02900 239 KHVDTGMGLERLASILQNKPSNYDTDLFMPIFDAIQEATGARPYAGKVGAEDDDRVDMAYRVVADHIRTLSFAIADGVVP 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 369 GNEGREYVLRRILRRAVRYGKEILKAEEGFFNGLVSSVIRVMGDVFTELKEHEKKITDIIKEEEASFCKTLAKGIEKFRK 448
Cdd:PLN02900 319 SNEGRGYVLRRLLRRAVRYGRLLLGAEEGFFPALVEVVVELSGDVFPEVKKNEKRITEIIAEEELSFGKTLEKGIEKFKK 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 449 AGQAVQ---GNTLSGDDAFILWDTYGFPLDLTQLMAEERGLLVDVDGFNKAMEEARERSRSAQNKQAGGAIVMDADATST 525
Cdd:PLN02900 399 ALAAAKangGPVLSGKDAFLLYDTYGFPVDLTELMAEERGVTVDMEGFEAAMEEARERSRAAHLKAGGGAIELAAEATSW 478
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 526 LHKAGVSATDDSFKYIWFQDHESELKAIYTGSTFLESSAASDNVGLVLGSTSFYAEQGGQIFDTGLIEGSFG-TFNVCNV 604
Cdd:PLN02900 479 LQKQGVAATDDFLKYDWLSDHEAVVKAILTGGGFVESVSEGDEVGIVLDKTSFYAESGGQIGDTGVLEGSGGaVVEVSDV 558
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 605 QIFGGFVLHIGYLSKetGEVSVGDKVICKVDYERRKLIAPNHTCTHMLNYALKEVLGDHIDQKGSIVLPEKLRFDFSHGK 684
Cdd:PLN02900 559 QKAGGFVLHIGTVTE--GSVSVGDAVTCKVDYDRRRRIAPNHTATHLLNSALKEVLGDHVDQKGSLVAFEKLRFDFSHGK 636
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 685 PVDPEDLRRIESIVNKQIKDELDVFSKEAVLSEAKRIKGLRAVFGEVYPDPVRVVSIGRKvedlladpennewslLSSEF 764
Cdd:PLN02900 637 PMTPEELREVESLVNEWIGDALPVEAKEMPLADAKRINGLRAVFGEKYPDPVRVVSVGGV---------------YSMEL 701
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 765 CGGTHITNTREAKAFALLSEEGIAKGIRRVTAVTTECAFDALNAASLLEREVEDASRAEGSALEKKVSALKSRVDAAIIP 844
Cdd:PLN02900 702 CGGTHVSNTAEAEAFKLLSEEGIAKGIRRITAVTGGAAVEAINAADSLERELDSALKVEGSDLEKKVASLKSRVDAAVIP 781
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 845 AAKKADIRTKIASLQNEVRKAQKKIAEQNLKKSVKLATEAAESAASDGKTFCIIQLDVGLDAAAVREAVSKVMEKK-GMS 923
Cdd:PLN02900 782 AAKKEEIRARVSALQKELRAAQKEAAALRAKLAVAKATELASKALSAGKSVLVARLDVGVDAAALKEAAEKVIAKLgDPA 861
|
890 900 910 920 930 940 950
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 30694735 924 IMVFSTDESTNKAVVCAGVPEKSDQfKPLDVTEWLtTALGPLKGRCGKGKGGLASGQGTDASQVQAALDMASSFASM 1000
Cdd:PLN02900 862 AVVLSSDEEKGKVSLVAAVPPGVVK-KGLKAGKWL-GAIAKLCGGGGGGKPGFAQGQGRDAEKLDAALEKARAFAVA 936
|
|
| AlaS |
COG0013 |
Alanyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Alanyl-tRNA ... |
64-942 |
0e+00 |
|
Alanyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Alanyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439784 [Multi-domain] Cd Length: 880 Bit Score: 1031.93 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 64 VRDTYVDFFRGKGHKFWPSSPVVPHNDPTLLFANAGMNQYKPIFLGTADPntelsKLSRACNTQKCIRAGGKHNDLDDVG 143
Cdd:COG0013 7 IRQKFLDFFESKGHTIVPSSSLVPKNDPTLLFTNAGMVQFKPYFLGQEKP-----PYPRATTSQKCVRTGGKHNDLENVG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 144 KDTYHHTFFEMLGNWSFGDYFKKEAIEWAWELLTKVYGLPTDRIYATYFGGDEkaglqpdnEARDIWLKV--LPSGRVLP 221
Cdd:COG0013 82 YTARHHTFFEMLGNFSFGDYFKEEAIAWAWELLTEVLGLPKERLWVTVYEDDD--------EAYDIWKKEigVPEERIIR 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 222 FGCKDNFWEMGDTGPCGPCTEIHYDR---IGNrDAASLVNNDDPTCLEIWNLVFIQFNRESDGSLKPLPAKHVDTGMGFE 298
Cdd:COG0013 154 LGKKDNFWEMGDTGPCGPCSEIFYDRgpeYGG-GPPGSPGEDGDRYIEIWNLVFMQFNRDEDGTLTPLPKKNIDTGMGLE 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 299 RLTSVLQNKMSNYDTDVFMPIFDDIQKATGaRPYsGKVGPEDVdrvdmAYRVVADHIRTLSFAIADGSRPGNEGREYVLR 378
Cdd:COG0013 233 RIAAVLQGVHSNYETDLFRPLIEAAAELTG-VKY-GADEEDDV-----SLRVIADHIRAVAFLIADGVLPSNEGRGYVLR 305
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 379 RILRRAVRYGKeILKAEEGFFNGLVSSVIRVMGDVFTELKEHEKKITDIIKEEEASFCKTLAKGIEKFRKA---GQAVQG 455
Cdd:COG0013 306 RILRRAVRHGR-LLGIKEPFLYKLVPVVVEEMGDAYPELKEKQELIEKVLKAEEERFLRTLERGLKLLDEAiakLKAAGG 384
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 456 NTLSGDDAFILWDTYGFPLDLTQLMAEERGLLVDVDGFNKAMEEARERSRSAQNKQAGGAIvmDADATSTLHKAGvsATD 535
Cdd:COG0013 385 KVLSGEDAFKLYDTYGFPLDLTEEIARERGLTVDEEGFEAAMEEQRERARAAAKFSGDAAV--DGVWRELLEEGG--PTE 460
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 536 ----DSFKyiwfqdHESELKAIYTGSTFLESSAASDNVGLVLGSTSFYAEQGGQIFDTGLIEGSFGTFNVCNVQ-IFGGF 610
Cdd:COG0013 461 fvgyDTLE------AEAKVLALVKDGELVDSAKAGEEVEVVLDRTPFYAESGGQVGDTGTIEGDGGVFEVTDTQkPPGGL 534
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 611 VLHIGYLskETGEVSVGDKVICKVDYERRKLIAPNHTCTHMLNYALKEVLGDHIDQKGSIVLPEKLRFDFSHGKPVDPED 690
Cdd:COG0013 535 IVHIGKV--EEGELKVGDTVTAQVDAERRRAIARNHSATHLLHAALREVLGEHVTQAGSLVAPDRLRFDFSHFEALTPEE 612
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 691 LRRIESIVNKQIKDELDVFSKEAVLSEAKRiKGLRAVFGEVYPDPVRVVSIGrkvedlladpennEWSLlssEFCGGTHI 770
Cdd:COG0013 613 LAEIEDLVNEKIRENLPVETREMPLDEAKA-LGAMALFGEKYGDEVRVVSIG-------------DFSR---ELCGGTHV 675
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 771 TNTREAKAFALLSEEGIAKGIRRVTAVTTECAFDALNAaslLEREVEDASraegsalekkvSALKSRVDaaiipaakkaD 850
Cdd:COG0013 676 SRTGDIGLFKIVSESSVAAGVRRIEAVTGEAALEYLRE---QEALLKELA-----------ELLKAPPE----------E 731
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 851 IRTKIASLQNEVRKAQKKIAEQNLKK-SVKLATEAAESAASDGKTFCIIQLDvGLDAAAVREAVSKVMEKKGMSIMVFST 929
Cdd:COG0013 732 LPERVEALLEELKELEKELEQLKAKLaSAAADDLLAQAEEIGGVKVLAARVE-GVDAKDLRDLADDLKDKLGSGVVVLAS 810
|
890
....*....|...
gi 30694735 930 DEStNKAVVCAGV 942
Cdd:COG0013 811 VAD-GKVSLVAGV 822
|
|
| tRNA-synt_2c |
pfam01411 |
tRNA synthetases class II (A); Other tRNA synthetase sub-families are too dissimilar to be ... |
64-638 |
0e+00 |
|
tRNA synthetases class II (A); Other tRNA synthetase sub-families are too dissimilar to be included. This family includes only alanyl-tRNA synthetases.
Pssm-ID: 279719 [Multi-domain] Cd Length: 548 Bit Score: 833.46 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 64 VRDTYVDFFRGKGHKFWPSSPVVPHNDPTLLFANAGMNQYKPIFLGTADPntelSKLSRACNTQKCIRAGgkhnDLDDVG 143
Cdd:pfam01411 2 IRQTFLDFFEKKGHTRVPSSPVVPRNDPTLLFTNAGMNQFKPIFLGGVAK----PPYNRATNSQKCIRAG----DLENVG 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 144 KDTYHHTFFEMLGNWSFGDYFKKEAIEWAWELLTKVYGLPTDRIYATYFGGDEkaglqpdnEARDIWLKV--LPSGRVLP 221
Cdd:pfam01411 74 RTGRHHTFFEMLGNFSFGDYFKEEAIEYAWELLTKELGLPPERLYVTVFEWDD--------EAGPIWEKIvgGPEERILR 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 222 FGCKDNFWEMGDTGPCGPCTEIHYDR---IGNRDAASLVNNDDPTCLEIWNLVFIQFNRESDGSLKPLPAKHVDTGMGFE 298
Cdd:pfam01411 146 FGDKDNFWEMGDTGPCGPCSEIDYDRgeeIGGWDSGGTPTADDDRFLEIWNLVFMQFNRENDGTLKPLPKKSIDTGMGLE 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 299 RLTSVLQNKMSNYDTDVFMPIFDDIQKATGARPYSgkvgpedVDRVDMAYRVVADHIRTLSFAIADGSRPGNEGREYVLR 378
Cdd:pfam01411 226 RLVAVLQDVRSNYDTDVFIPVIELIEEISGARYYT-------VDETDEAYRVIADHTRALTFALADGVVPSNEGRGYVLR 298
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 379 RILRRAVRYGKEiLKAEEGFFNGLVSSVIRVMGDVFTELKEHEKKITDIIKEEEASFCKTLAKGIEKFRKAGQAV--QGN 456
Cdd:pfam01411 299 RILRRAVRHAKK-LGLKEPFLYDLVPTVVEVLGDAYPELKEDEDFIQEILELEEERFAKTLERGLRLLERLIAKLkkGKK 377
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 457 TLSGDDAFILWDTYGFPLDLTQLMAEERGLLVDVDGFNKAMEEARERSRsaQNKQAGGAiVMDADATSTLHkagvsATDD 536
Cdd:pfam01411 378 TLPGEDAFKLYDTYGFPVDLTKEIAEERGLKVDMPGFEYAMVEQRERSK--QAVKEKGE-KLDVSALKELP-----ATTE 449
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 537 SFKYIWFQDhESELKAIYTGSTFLESSAASDNVGLVLGSTSFYAEQGGQIFDTGLIEGSFGTFNVCNVQIFGGFVLHIGY 616
Cdd:pfam01411 450 FLGYDDLES-EAKILALPKDGEFVAEVLAGQEGGVILDRTPFYAESGGQIGDTGYIIGDGGEFRVTDVQKYGGVVVHKGK 528
|
570 580
....*....|....*....|..
gi 30694735 617 LskETGEVSVGDKVICKVDYER 638
Cdd:pfam01411 529 L--ESGKLKVGDKVIAVIDEDR 548
|
|
| alaS |
TIGR00344 |
alanine--tRNA ligase; The model describes alanine--tRNA ligase. This enzyme catalyzes the ... |
64-958 |
0e+00 |
|
alanine--tRNA ligase; The model describes alanine--tRNA ligase. This enzyme catalyzes the reaction (tRNAala + L-alanine + ATP = L-alanyl-tRNAala + pyrophosphate + AMP). [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 273026 [Multi-domain] Cd Length: 845 Bit Score: 810.07 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 64 VRDTYVDFFRGKGHKFWPSSPVVPHNDPTLLFANAGMNQYKPIFLGTADPNTelsklSRACNTQKCIRAggkhNDLDDVG 143
Cdd:TIGR00344 2 IRQTFLDFFKEKGHQVIPSAPLVPRNDPTLLLTNAGMAQFKPIFTGIVKPPS-----NRLTNAQPCIRL----NDLENVG 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 144 KDTYHHTFFEMLGNWSFGDYFKKEAIEWAWELLTKVYGLPTDRIYATYFGGDEKAGLQPDNeardiwlKVLPSGRVLPFG 223
Cdd:TIGR00344 73 RTARHHTLFEMLGNFSFGDYFKEEAIAFAWELLTEVLGLDKERLYVTVYEDDEEAYKIWEK-------IGIPADRIIKCD 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 224 CKDNFWEMGDtGPCGPCTEIHYDRIGNRDAASLVNNDDptCLEIWNLVFIQFNRESDGSLKPLPAKHVDTGMGFERLTSV 303
Cdd:TIGR00344 146 AKDNFWDMGD-GPCGPCTEIYYDFVGGKPGEPLEENDR--YLEVWNLVFMQFNRDPDGNYTPLPKKNIDTGMGLERFVAV 222
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 304 LQNKMSNYDTDVFMPIFDDIQKATGARPYSGKVGPEDVDRVD--MAYRVVADHIRTLSFAIADGSRPGNEGREYVLRRIL 381
Cdd:TIGR00344 223 LQGVPTNYDTDIFLPLIEKIEEITGVKYDSNNAGIMDEKRVEdlRSLRVIADHTRAIAFMLADGVVPSNEGRGYVLRRLI 302
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 382 RRAVRYGKEiLKAEEGFFNGLVSSVIRVMGDVFTELKEHEKKITDIIKEEEASFCKTLAKGIEKFRKAGQAVQGNTLSGD 461
Cdd:TIGR00344 303 RRALRHGKK-LGLKEAFLYKLVPTLIEVLGDYYPELKEKQEFVEQILELEEERFAKTLERGLRLFEKLLKKTGKKELDGE 381
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 462 DAFILWDTYGFPLDLTQLMAEERGLLVDVDGFNKAMEEARERSRSAQNKQAGGAIVMDADATSTLhkagvsatddsFKYi 541
Cdd:TIGR00344 382 DAFKLYDTYGFPVELTKEIAEERGLTVDMPGFEALMAEQRERSKQNSQFQEQEIALVNVYPATEF-----------LGY- 449
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 542 wfQDHESELK--AIYTGSTFLESSAASDNVGLVLGSTSFYAEQGGQIFDTGLIEGSFGTFNVCNVQIFGGFVLHIGYLsk 619
Cdd:TIGR00344 450 --DDLEFEAKviGLFDDGYLVEQALAGQSVYVILDQTPFYAESGGQIGDTGYLIANDGKFRVVDVQKPNGVVFHFGEV-- 525
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 620 ETGEVSVGDKVICKVDYERRKLIAPNHTCTHMLNYALKEVLGDHIDQKGSIVLPEKLRFDFSHGKPVDPEDLRRIESIVN 699
Cdd:TIGR00344 526 EGGSLKVGDKVIAVIDEKRRFRIMRNHSATHLLHAALQKVLGNHVWQAGSLVSFKKLRFDFSHFRALTREELEEIEDLAN 605
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 700 KQIKDELDVFSKEAVLSEAKRIKGLRAvFGEVYP--DPVRVVSIGRkvedlladpennewslLSSEFCGGTHITNTREAK 777
Cdd:TIGR00344 606 EQILANIPIKVIFMDLDEAKRKGAFAL-FGEKYVpgEKVRVVSVGD----------------FSVELCGGTHVRNTGEIG 668
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 778 AFALLSEEGIAKGIRRVTAVTTECAFDALNAASLLEREVEDASRAEGSALEKKVSALKsrvdaaiipaakkadirTKIAS 857
Cdd:TIGR00344 669 LFKIVKESGIAAGVRRIEAVTGEAAIEYLNEQEDKLKELADILKVTPNELPKKVERFF-----------------EEWKA 731
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 858 LQNEVRKAQKKIAEQnlkksvKLATEAAESAASDGKTFCIIQLDvGLDAAAVREAVSKVMEKKGMSIMVFSTDESTNKAV 937
Cdd:TIGR00344 732 LQKELESLKLKIADQ------KIDELKDKAETINGVKVLVEVVD-AKDMKSLKTMADRLKSKLGSAIYVLASFAEGKVKL 804
|
890 900
....*....|....*....|.
gi 30694735 938 VCaGVPEKSDQfKPLDVTEWL 958
Cdd:TIGR00344 805 VC-GVSNDVLT-KKIKAGELI 823
|
|
| PRK01584 |
PRK01584 |
alanyl-tRNA synthetase; Provisional |
61-797 |
1.61e-150 |
|
alanyl-tRNA synthetase; Provisional
Pssm-ID: 234962 [Multi-domain] Cd Length: 594 Bit Score: 459.62 E-value: 1.61e-150
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 61 AKRVRDTYVDFFRGKGHKFWPSSPVVPHNDPTLLFANAGMNQYKPIFLGTADPntelsKLSRACNTQKCIRAGgkhnDLD 140
Cdd:PRK01584 3 LDELRKKYIDFFKSKGHVEIAGKSLIPENDPTVLFTTAGMHPLVPYLLGEPHP-----SGTRLVDVQKCLRTG----DID 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 141 DVGkDTYHHTFFEMLGNWSFGDYFKKEAIEWAWELLT--KVYGLPTDRIYATYFGGDEKAglQPDNEARDIWLKV-LPSG 217
Cdd:PRK01584 74 EVG-DLSHLTFFEMLGNWSLGAYFKEESIKYSFEFLTspDYLNIPKDKLYVTVFEGDEEI--PRDEETASVWESLgIPKD 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 218 RVLPFGCKDNFW-EMGDTGPCGPCTEIHYDRigNRDAASlvNNDDPTC-----LEIWNLVFIQFNRESDGSLKPLPAKHV 291
Cdd:PRK01584 151 RIFYLSREHNWWgPVGETGPCGPDTEIFVDT--GKPKCS--VNCRPTCscgkyFEIWNNVFMQYNKDEDGNYEELKRKCV 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 292 DTGMGFERLTSVLQNKMSNYDTDVFMPIFDDIQKatgarpYSGKVGPEDVDRvDMAYRVVADHIRTLSFAIAD--GSRPG 369
Cdd:PRK01584 227 DTGMGIERTIAFLQGKSSVYDTEAFTPIIKRIEK------ISGKIYGQNEED-DRSIRIIADHIRAACFILGDpfVVLPS 299
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 370 NEGREYVLRRILRRAVRYGKEiLKAEEGFFNGLVSSVIRVMGDVFTELKEHEKKITDIIKEEEASFCKTLAKGIEKFRK- 448
Cdd:PRK01584 300 NVGQGYVLRRLIRRSIRHAKK-LGIESHFLADLVDSVEEIYGSFYPELTEKKDFIKEELNKEEEKFFKTLRKGEQEFIKl 378
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 449 AGQAVQGNTLSGDDAFILWDTYGFPLDLTQLMAEERGLLVDVDGFNKAMEEARERSRsaqnkqAGGaivmdadatstlhk 528
Cdd:PRK01584 379 IPNLGSSKIIPGDIAFKLYDTYGFPYEITEELASEYGFTVDREGFDEHFKKHQKVSK------KGA-------------- 438
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 529 agvsatDDSFKyiwfqdheselkaiytgstflessaasdnvglvlgstsfyaeqggqifdtgliegsfgtfnvcnvqifG 608
Cdd:PRK01584 439 ------DKVFK--------------------------------------------------------------------G 444
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 609 GFVLHigylsketgevsvgdkvickvDYERRKLiapnHTCTHMLNYALKEVLGDHIDQKGSIVLPEKLRFDFSHGKPVDP 688
Cdd:PRK01584 445 GLADH---------------------SYETTKL----HTATHLLHKALRLVLGDHVRQKGSNITAERLRFDFSHPEKMTD 499
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 689 EDLRRIESIVNKQIKDELDVFSKEAVLSEAKRiKGLRAVFGEVYPDPVRVVSIGRkvedlladpennewslLSSEFCGGT 768
Cdd:PRK01584 500 DEIKKVEDIVNLQIKNDLSVKKEVMSLEEARE-KGAMALFGEKYEDIVKVYEIDG----------------FSKEVCGGP 562
|
730 740
....*....|....*....|....*....
gi 30694735 769 HITNTREAKAFALLSEEGIAKGIRRVTAV 797
Cdd:PRK01584 563 HVENTGELGTFKIQKEQSSSSGVRRIRAI 591
|
|
| AlaRS_core |
cd00673 |
Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is ... |
61-307 |
9.02e-139 |
|
Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent formation of the enzyme bound aminoacyl-adenylate. Class II assignment is based upon its predicted structure and the presence of three characteristic sequence motifs.
Pssm-ID: 238360 [Multi-domain] Cd Length: 232 Bit Score: 415.22 E-value: 9.02e-139
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 61 AKRVRDTYVDFFRGKGHKFWPSSPVVPHNDPTLLFANAGMNQYKPIFLGTADPNTelsklSRACNTQKCIRAGGKHNdld 140
Cdd:cd00673 1 ASEIRETFLSFFEKKGHTRVPSSPVVPRDDPTLLFTNAGMNQFKPIFLGEVPPPA-----NRLVNSQKCIRAGDIDN--- 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 141 dVGKDTYHHTFFEMLGNWSFGDYFKKEAIEWAWELLTKVYGLPTDRIYATYFGGDEKAglqpdnEARDIWLKVLPSGRVL 220
Cdd:cd00673 73 -VGKTGRHHTFFEMLGNFSFGDYFKEEAIAFAWELLTEVLGLPKDRLYVSVFEGDDEE------EAIWWWKIGLPGIRIE 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 221 PFGCKDNFWEMGDTGPCGPCTEIHYDRIGNRDAASLVNNDDPTCLEIWNLVFIQFNRESDGSLKPLPAKHVDTGMGFERL 300
Cdd:cd00673 146 RIGFKDNFWEMGGNGPCGPCSEIFYDRGEERDAASLPNEDDDRYLEIWNLVFMQYNRDADGTYRPLPKKIVDTGMGLERL 225
|
....*..
gi 30694735 301 TSVLQNK 307
Cdd:cd00673 226 VWVLQGV 232
|
|
| AlaX |
COG2872 |
Ser-tRNA(Ala) deacylase AlaX (editing enzyme) [Translation, ribosomal structure and biogenesis] ... |
564-795 |
8.37e-29 |
|
Ser-tRNA(Ala) deacylase AlaX (editing enzyme) [Translation, ribosomal structure and biogenesis];
Pssm-ID: 442119 [Multi-domain] Cd Length: 238 Bit Score: 115.68 E-value: 8.37e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 564 AASDNVGLVLGSTSFYAEQGGQIFDTGLIEGSFGTFNVCNVQIFGGFVLHIGylsKETGEVSVGDKVICKVDYERRKLIA 643
Cdd:COG2872 21 AVTEEGGVVLDRTAFYPTGGGQPGDTGTLVWDGKEIRVVDVRKEDGEIVHVL---EGAPLPEVGDEVTGEIDWERRYRHM 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 644 PNHTCTHMLNYALKEVLGDHIDqKGSIVlPEKLRFDFSHGKPvDPEDLRRIESIVNKQIKDELDVFSKEAVLSEAKRIKG 723
Cdd:COG2872 98 RLHTALHLLSAVVYREYGAPVT-GGQIG-EDRARIDFDLPEF-DEEDLEEIEAEANELIAADLPVRIYWITREELEAIPG 174
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 30694735 724 L-RAVFGEVYP--DPVRVVSIGRkVeDLLAdpennewsllssefCGGTHITNTREAKAFALLSEEGIAKGIRRVT 795
Cdd:COG2872 175 LvRTMSVLPPPgvGRVRIVEIGG-V-DLQP--------------CGGTHVANTGEIGRIKITKIEKKGKGNRRVY 233
|
|
| tRNA_SAD |
smart00863 |
Threonyl and Alanyl tRNA synthetase second additional domain; The catalytically active form of ... |
736-794 |
6.69e-13 |
|
Threonyl and Alanyl tRNA synthetase second additional domain; The catalytically active form of threonyl/alanyl tRNA synthetase is a dimer. Within the tRNA synthetase class II dimer, the bound tRNA interacts with both monomers making specific interactions with the catalytic domain, the C-terminal domain, and this SAD domain (the second additional domain). The second additional domain is comprised of a pair of perpendicularly orientated antiparallel beta sheets, of four and three strands, respectively, that surround a central alpha helix that forms the core of the domain.
Pssm-ID: 197931 [Multi-domain] Cd Length: 43 Bit Score: 63.56 E-value: 6.69e-13
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 30694735 736 VRVVSIGRkvedlladpennewslLSSEFCGGTHITNTREAKAFALLSEEGIAKGIRRV 794
Cdd:smart00863 1 VRVVSIGD----------------FSVELCGGTHVPNTGEIGAFKILSVSGAYWGLQRI 43
|
|
| PLN02961 |
PLN02961 |
alanine-tRNA ligase |
571-794 |
1.83e-12 |
|
alanine-tRNA ligase
Pssm-ID: 178546 [Multi-domain] Cd Length: 223 Bit Score: 67.80 E-value: 1.83e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 571 LVLGSTSFYAEQGGQIFDTGLIEGSFGTFNVCNVQI--FGGFVLHIGYLSKETGEV----SVGDKVICKVDYERRKLIAP 644
Cdd:PLN02961 5 LVLDRTIFHPQGGGQPSDTGRIVISGGDTKFSVQDVrrKDGVVYHYGVFEGSNPESaspfEAGDEVTVTVDESRRKLHSR 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 645 NHTCTHMLNYALKEV-LGDHIDQKGsIVLPEKLRFDFShGKpVDPEDL----RRIESIVNKQIKDELDVFSKEAVLSEAK 719
Cdd:PLN02961 85 LHSAGHLLDVCMARVgLGPLEPGKG-YHFPDGPFVEYK-GK-IPQGELdskqDELEAEANELIAEGGKVSAAVLPYDEAA 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 720 RIKGLRAvfgevyPDPV------RVVSIGrkveDLLADPennewsllssefCGGTHITNTREAKAFAlLSEEGIAKGIRR 793
Cdd:PLN02961 162 ELCGGSL------PDYIakdstpRIVKIG----DSPGCP------------CGGTHVADVSEITSVK-VTQIRVKKGVTR 218
|
.
gi 30694735 794 V 794
Cdd:PLN02961 219 V 219
|
|
| tRNA_SAD |
pfam07973 |
Threonyl and Alanyl tRNA synthetase second additional domain; The catalytically active from of ... |
736-794 |
7.51e-12 |
|
Threonyl and Alanyl tRNA synthetase second additional domain; The catalytically active from of threonyl/alanyl tRNA synthetase is a dimer. Within the tRNA synthetase class II dimer, the bound tRNA interacts with both monomers making specific interactions with the catalytic domain, the C-terminal domain, and this domain (the second additional domain). The second additional domain is comprised of a pair of perpendicularly orientated antiparallel beta sheets, of four and three strands, respectively, that surround a central alpha helix that forms the core of the domain.
Pssm-ID: 429764 [Multi-domain] Cd Length: 43 Bit Score: 60.54 E-value: 7.51e-12
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 30694735 736 VRVVSIGrkvedlladpennEWSLlssEFCGGTHITNTREAKAFALLSEEGIAKGIRRV 794
Cdd:pfam07973 1 VRVVSIG-------------DFDV---DLCGGTHVPNTGEIGAFKILKGESKNKGLRRI 43
|
|
| DHHA1 |
pfam02272 |
DHHA1 domain; This domain is often found adjacent to the DHH domain pfam01368 and is called ... |
855-998 |
2.11e-07 |
|
DHHA1 domain; This domain is often found adjacent to the DHH domain pfam01368 and is called DHHA1 for DHH associated domain. This domain is diagnostic of DHH subfamily 1 members. This domains is also found in alanyl tRNA synthetase, suggesting that this domain may have an RNA binding function. The domain is about 60 residues long and contains a conserved GG motif.
Pssm-ID: 396724 [Multi-domain] Cd Length: 139 Bit Score: 50.90 E-value: 2.11e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 855 IASLQNEVRKAQKKIAE-QNLKKSVKLATEAAESAASDGKTFCIIQLDVGLDAAAVREAVSKVMEKKGMSIMVFSTDEST 933
Cdd:pfam02272 1 LESLNEELKELEKELEElKEALALLKAKELLEKAEEINGVKVLVAEVGEGWDAGALGIAADRLKKKLGDPVIVLVAKEDG 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 30694735 934 NKAVVCAGVPEKsdqfKPLDVTEWLTTALGPLK------GrcgkgkggLASGQGTDASQVQAALDMASSFA 998
Cdd:pfam02272 81 DKVKVSARSSKD----KGVDAGELLKEVAAILGggggghD--------LAAGAGIDAEKLDEALELLEEAI 139
|
|
| ThrS |
COG0441 |
Threonyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Threonyl-tRNA ... |
645-783 |
2.32e-05 |
|
Threonyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Threonyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 440210 [Multi-domain] Cd Length: 639 Bit Score: 48.49 E-value: 2.32e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 645 NHTCTHMLNYALKEVLgdhidqkgsivlPE-KL----------RFDFSHGKPVDPEDLRRIESIVNKQIKDELDvFSKEa 713
Cdd:COG0441 72 RHSAAHLLAQAVKRLY------------PDaKLtigpviengfYYDFDLERPFTPEDLEKIEKEMKEIIKEDLP-IERE- 137
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 30694735 714 VLSEAKrikgLRAVF---GEVYpdpvrvvsigrKVEdLLAD-PENNEWSLLSS-EF---CGGTHITNTREAKAFALLS 783
Cdd:COG0441 138 EVSREE----AIELFkekGEPY-----------KVE-LIEDiPEDEEISLYRQgEFvdlCRGPHVPSTGKIKAFKLLS 199
|
|
| PRK12444 |
PRK12444 |
threonyl-tRNA synthetase; Reviewed |
646-786 |
9.13e-05 |
|
threonyl-tRNA synthetase; Reviewed
Pssm-ID: 183530 [Multi-domain] Cd Length: 639 Bit Score: 46.28 E-value: 9.13e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30694735 646 HTCTHMLNYALKEVLGDhIDQKGSIVLPEKLRFDFSHGKPVDPEDLRRIESIVNKQIKDELDVFSKEAVLSEAKRIkglr 725
Cdd:PRK12444 77 HSAAHILAQAVKRLYGD-VNLGVGPVIENGFYYDMDLPSSVNVEDLRKIEKEMKKIINENIKIERVEVSREEAAKL---- 151
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 30694735 726 avFGEVYpDPVrvvsigrKVEDLLADPENNEWSLLSS-EF---CGGTHITNTREAKAFALLSEEG 786
Cdd:PRK12444 152 --FQEMN-DRL-------KLELLEAIPSGESITLYKQgEFvdlCRGPHLPSTGYLKAFQLTHVSG 206
|
|
| |
