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Conserved domains on  [gi|30693796|ref|NP_175080|]
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HSP40/DnaJ peptide-binding protein [Arabidopsis thaliana]

Protein Classification

J domain-containing protein( domain architecture ID 10180526)

J domain-containing protein similar to the N-terminal conserved domain (called J domain) of DnaJ-like proteins, which is involved in regulating the ATPase activity of heat shock protein 70 (Hsp70) by ATP hydrolysis

Gene Ontology:  GO:0006457
PubMed:  9585179|23894646|15170475

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DnaJ_C cd10747
C-terminal substrate binding domain of DnaJ and HSP40; The C-terminal region of the DnaJ/Hsp40 ...
 178-341 4.61e-47

C-terminal substrate binding domain of DnaJ and HSP40; The C-terminal region of the DnaJ/Hsp40 protein mediates oligomerization and binding to denatured polypeptide substrate. DnaJ/Hsp40 is a widely conserved heat-shock protein. It prevents the aggregation of unfolded substrate and forms a ternary complex with both substrate and DnaK/Hsp70; the N-terminal J-domain of DnaJ/Hsp40 stimulates the ATPase activity of DnaK/Hsp70.


:

Pssm-ID: 199909 [Multi-domain]  Cd Length: 158  Bit Score: 156.82  E-value: 4.61e-47
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30693796 178 SPTEKKLRCTLEELCNGCTKKIKIKRDVITslgekCEEEEMVEIKVKPGWKGGTKVTFEGKGNEAMRSVPA-DLTFVIVE 256
Cdd:cd10747   1 ADLRYDLELTLEEAYFGKEKEIKIPRKVTR-----VREKKTLTVKIPAGVDDGQRLRLRGEGDAGPNGGPPgDLYVVIRV 75

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30693796 257 KEHEVFKREGDDLEMAVEVSLLEALTGCELSVALLDGDnMRLRIEDVIHPGYVTVVQGKGMPNLKeKGKRGDLRVRFRTK 336
Cdd:cd10747  76 KPHPVFRRDGNDLYCEVPISLTEALLGGEIEVPTLGGK-VKLKIPPGTQPGTVLRLKGKGMPRLR-GGGRGDLYVEVKVE 153


                ....*
gi 30693796 337 FPQHL 341
Cdd:cd10747 154 FPKKL 158
 
Name Accession Description Interval E-value
DnaJ_C cd10747
C-terminal substrate binding domain of DnaJ and HSP40; The C-terminal region of the DnaJ/Hsp40 ...
 178-341 4.61e-47

C-terminal substrate binding domain of DnaJ and HSP40; The C-terminal region of the DnaJ/Hsp40 protein mediates oligomerization and binding to denatured polypeptide substrate. DnaJ/Hsp40 is a widely conserved heat-shock protein. It prevents the aggregation of unfolded substrate and forms a ternary complex with both substrate and DnaK/Hsp70; the N-terminal J-domain of DnaJ/Hsp40 stimulates the ATPase activity of DnaK/Hsp70.


Pssm-ID: 199909 [Multi-domain]  Cd Length: 158  Bit Score: 156.82  E-value: 4.61e-47
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30693796 178 SPTEKKLRCTLEELCNGCTKKIKIKRDVITslgekCEEEEMVEIKVKPGWKGGTKVTFEGKGNEAMRSVPA-DLTFVIVE 256
Cdd:cd10747   1 ADLRYDLELTLEEAYFGKEKEIKIPRKVTR-----VREKKTLTVKIPAGVDDGQRLRLRGEGDAGPNGGPPgDLYVVIRV 75

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30693796 257 KEHEVFKREGDDLEMAVEVSLLEALTGCELSVALLDGDnMRLRIEDVIHPGYVTVVQGKGMPNLKeKGKRGDLRVRFRTK 336
Cdd:cd10747  76 KPHPVFRRDGNDLYCEVPISLTEALLGGEIEVPTLGGK-VKLKIPPGTQPGTVLRLKGKGMPRLR-GGGRGDLYVEVKVE 153


                ....*
gi 30693796 337 FPQHL 341
Cdd:cd10747 154 FPKKL 158
DnaJ_C pfam01556
DnaJ C terminal domain; This family consists of the C terminal region of the DnaJ protein. It ...
 181-338 5.13e-39

DnaJ C terminal domain; This family consists of the C terminal region of the DnaJ protein. It is always found associated with pfam00226 and pfam00684. DnaJ is a chaperone associated with the Hsp70 heat-shock system involved in protein folding and renaturation after stress. The two C-terminal domains CTDI and CTDII, both incorporated in this family are necessary for maintaining the J-domains in their specific relative positions. Structural analysis of PDB:1nlt shows that PF00684 is nested within this DnaJ C-terminal region.


Pssm-ID: 460251 [Multi-domain]  Cd Length: 213  Bit Score: 137.77  E-value: 5.13e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30693796   181 EKKLRCTLEELCNGCTKKIKIKRDVI------------------------------------------------------ 206
Cdd:pfam01556   2 EYELELTLEEAYFGCTKKIKITRNVIcdtcggsgakpgtspktcpccggggqvrrqfgffstctccpccggggkiidkcc 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30693796   207 -TSLGEKCEEEEMVEIKVKPGWKGGTKVTFEGKGNEAMRSVPA-DLTFVIVEKEHEVFKREGDDLEMAVEVSLLEALTGC 284
Cdd:pfam01556  82 kCCGGGGVVEKKTLEVKIPAGVDDGQRIRLRGEGDAGENGGPPgDLYVVIRVKPHPVFRRDGDDLYCTVPISLTEALLGG 161

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 30693796   285 ELSVALLDGDnMRLRIEDVIHPGYVTVVQGKGMPNLKeKGKRGDLRVRFRTKFP 338
Cdd:pfam01556 162 TIEVPTLDGK-VKLKIPAGTQPGTVLRLKGKGMPRLK-GGGRGDLYVTVKVEVP 213
PRK14291 PRK14291
chaperone protein DnaJ; Provisional
 188-339 5.31e-25

chaperone protein DnaJ; Provisional


Pssm-ID: 237661 [Multi-domain]  Cd Length: 382  Bit Score: 104.47  E-value: 5.31e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30693796  188 LEELCNGCT-KKIKIKRDVITslgekceeeemveIKVKPGWKGGTKVTFEGKGNEAMRS-VPADLTFVIVEKEHEVFKRE 265
Cdd:PRK14291 207 LREPCSKCNgRGLVIKKETIK-------------VRIPPGVDNGSKLRVPGKGHAGRFGgPPGDLYIIVKVKPHPLFERR 273

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 30693796  266 GDDLEMAVEVSLLEALTGCELSVALLDGDNMRLRIEDVIHPGYVTVVQGKGMPNLKEKGkRGDLRVRFRTKFPQ 339
Cdd:PRK14291 274 GDNLYLDVNITVAEAVLGTELEVPLLDGKKEKVKIPPGTKEGDKIRVPGKGMPRLKGSG-YGDLVVRVHIDVPK 346
 
Name Accession Description Interval E-value
DnaJ_C cd10747
C-terminal substrate binding domain of DnaJ and HSP40; The C-terminal region of the DnaJ/Hsp40 ...
 178-341 4.61e-47

C-terminal substrate binding domain of DnaJ and HSP40; The C-terminal region of the DnaJ/Hsp40 protein mediates oligomerization and binding to denatured polypeptide substrate. DnaJ/Hsp40 is a widely conserved heat-shock protein. It prevents the aggregation of unfolded substrate and forms a ternary complex with both substrate and DnaK/Hsp70; the N-terminal J-domain of DnaJ/Hsp40 stimulates the ATPase activity of DnaK/Hsp70.


Pssm-ID: 199909 [Multi-domain]  Cd Length: 158  Bit Score: 156.82  E-value: 4.61e-47
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30693796 178 SPTEKKLRCTLEELCNGCTKKIKIKRDVITslgekCEEEEMVEIKVKPGWKGGTKVTFEGKGNEAMRSVPA-DLTFVIVE 256
Cdd:cd10747   1 ADLRYDLELTLEEAYFGKEKEIKIPRKVTR-----VREKKTLTVKIPAGVDDGQRLRLRGEGDAGPNGGPPgDLYVVIRV 75

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30693796 257 KEHEVFKREGDDLEMAVEVSLLEALTGCELSVALLDGDnMRLRIEDVIHPGYVTVVQGKGMPNLKeKGKRGDLRVRFRTK 336
Cdd:cd10747  76 KPHPVFRRDGNDLYCEVPISLTEALLGGEIEVPTLGGK-VKLKIPPGTQPGTVLRLKGKGMPRLR-GGGRGDLYVEVKVE 153


                ....*
gi 30693796 337 FPQHL 341
Cdd:cd10747 154 FPKKL 158
DnaJ_C pfam01556
DnaJ C terminal domain; This family consists of the C terminal region of the DnaJ protein. It ...
 181-338 5.13e-39

DnaJ C terminal domain; This family consists of the C terminal region of the DnaJ protein. It is always found associated with pfam00226 and pfam00684. DnaJ is a chaperone associated with the Hsp70 heat-shock system involved in protein folding and renaturation after stress. The two C-terminal domains CTDI and CTDII, both incorporated in this family are necessary for maintaining the J-domains in their specific relative positions. Structural analysis of PDB:1nlt shows that PF00684 is nested within this DnaJ C-terminal region.


Pssm-ID: 460251 [Multi-domain]  Cd Length: 213  Bit Score: 137.77  E-value: 5.13e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30693796   181 EKKLRCTLEELCNGCTKKIKIKRDVI------------------------------------------------------ 206
Cdd:pfam01556   2 EYELELTLEEAYFGCTKKIKITRNVIcdtcggsgakpgtspktcpccggggqvrrqfgffstctccpccggggkiidkcc 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30693796   207 -TSLGEKCEEEEMVEIKVKPGWKGGTKVTFEGKGNEAMRSVPA-DLTFVIVEKEHEVFKREGDDLEMAVEVSLLEALTGC 284
Cdd:pfam01556  82 kCCGGGGVVEKKTLEVKIPAGVDDGQRIRLRGEGDAGENGGPPgDLYVVIRVKPHPVFRRDGDDLYCTVPISLTEALLGG 161

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 30693796   285 ELSVALLDGDnMRLRIEDVIHPGYVTVVQGKGMPNLKeKGKRGDLRVRFRTKFP 338
Cdd:pfam01556 162 TIEVPTLDGK-VKLKIPAGTQPGTVLRLKGKGMPRLK-GGGRGDLYVTVKVEVP 213
PRK14291 PRK14291
chaperone protein DnaJ; Provisional
 188-339 5.31e-25

chaperone protein DnaJ; Provisional


Pssm-ID: 237661 [Multi-domain]  Cd Length: 382  Bit Score: 104.47  E-value: 5.31e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30693796  188 LEELCNGCT-KKIKIKRDVITslgekceeeemveIKVKPGWKGGTKVTFEGKGNEAMRS-VPADLTFVIVEKEHEVFKRE 265
Cdd:PRK14291 207 LREPCSKCNgRGLVIKKETIK-------------VRIPPGVDNGSKLRVPGKGHAGRFGgPPGDLYIIVKVKPHPLFERR 273

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 30693796  266 GDDLEMAVEVSLLEALTGCELSVALLDGDNMRLRIEDVIHPGYVTVVQGKGMPNLKEKGkRGDLRVRFRTKFPQ 339
Cdd:PRK14291 274 GDNLYLDVNITVAEAVLGTELEVPLLDGKKEKVKIPPGTKEGDKIRVPGKGMPRLKGSG-YGDLVVRVHIDVPK 346
PTZ00037 PTZ00037
DnaJ_C chaperone protein; Provisional
 232-342 7.55e-22

DnaJ_C chaperone protein; Provisional


Pssm-ID: 240236 [Multi-domain]  Cd Length: 421  Bit Score: 95.66  E-value: 7.55e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30693796  232 KVTFEGKGNEAMRSVPADLTFVIVEKEHEVFKREGDDLEMAVEVSLLEALTGCELSVALLDGDNMRLRIE--DVIHPGYV 309
Cdd:PTZ00037 239 KITFHGEADEKPNEIPGNVVFILNEKPHDTFKREGGDLFITKKISLYEALTGFVFYITHLDGRKLLVNTPpgEVVKPGDI 318

                         90       100       110
                 ....*....|....*....|....*....|...
gi 30693796  310 TVVQGKGMPNLKEKGKRGDLRVRFRTKFPQHLT 342
Cdd:PTZ00037 319 KVINNEGMPTYKSPFKKGNLYVTFEVIFPVDRK 351
PRK14278 PRK14278
chaperone protein DnaJ; Provisional
 156-346 4.12e-19

chaperone protein DnaJ; Provisional


Pssm-ID: 237654 [Multi-domain]  Cd Length: 378  Bit Score: 87.42  E-value: 4.12e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30693796  156 TVPRSFANPILYSsssakvaKPSPTEKKLRCTLEELCNGCTK--KIKIKRDVItslgekceeeemveIKVKPGWKGGTKV 233
Cdd:PRK14278 170 TVQRSFLGQVMTS-------RPCPTCRGVGEVIPDPCHECAGdgRVRARREIT--------------VKIPAGVGDGMRI 228

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30693796  234 TFEGKGNEAMRSVPA-DLTFVIVEKEHEVFKREGDDLEMAVEVSLLEALTGCELSVALLDGDNMRLRIEDVIHPGYVTVV 312
Cdd:PRK14278 229 RLAAQGEVGPGGGPAgDLYVEVHEQPHDVFVRDGDDLHCTVSVPMVDAALGTTVTVEAILDGPSEITIPPGTQPGSVITL 308

                        170       180       190
                 ....*....|....*....|....*....|....
gi 30693796  313 QGKGMPNLKEKGkRGDLRVRFRTKFPQHLTDEQR 346
Cdd:PRK14278 309 RGRGMPHLRSGG-RGDLHAHVEVVVPTRLDHEDI 341
PRK14286 PRK14286
chaperone protein DnaJ; Provisional
 221-356 9.13e-18

chaperone protein DnaJ; Provisional


Pssm-ID: 172774 [Multi-domain]  Cd Length: 372  Bit Score: 83.50  E-value: 9.13e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30693796  221 IKVKPGWKGGTKVTFEGKGNEAMRSVP-ADLTFVIVEKEHEVFKREGDDLEMAVEVSLLEALTGCELSVALLDGDNMRLR 299
Cdd:PRK14286 223 IKIPPGVETGSRLKVSGEGEAGPNGGPhGDLYVVTHIKKHELFERQGNDLILVRKISLAQAILGAEIEVPTIDGKKAKMK 302

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 30693796  300 IEDVIHPGYVTVVQGKGMPNLKEKGKrGDLRVRFRTKFPQHLTDEQRAEIHSILQDS 356
Cdd:PRK14286 303 IPEGTESGQVFRLKGHGMPYLGAYGK-GDQHVIVKIEIPKKITRRQRELIEEFARES 358
PRK10767 PRK10767
chaperone protein DnaJ; Provisional
 221-346 1.09e-17

chaperone protein DnaJ; Provisional


Pssm-ID: 236757 [Multi-domain]  Cd Length: 371  Bit Score: 83.27  E-value: 1.09e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30693796  221 IKVKPGWKGGTKVTFEGKGNEAMRSVPA-DLTFVIVEKEHEVFKREGDDLEMAVEVSLLEALTGCELSVALLDGdNMRLR 299
Cdd:PRK10767 215 VKIPAGVDTGDRIRLSGEGEAGERGGPAgDLYVQIHVKEHPIFERDGNDLYCEVPISFTTAALGGEIEVPTLDG-RVKLK 293

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 30693796  300 IEDVIHPGYVTVVQGKGMPNLKeKGKRGDLRVRFRTKFPQHLTDEQR 346
Cdd:PRK10767 294 IPEGTQTGKLFRLRGKGVKSVR-SGARGDLYCQVVVETPVNLTKRQK 339
PRK14277 PRK14277
chaperone protein DnaJ; Provisional
 192-347 1.59e-17

chaperone protein DnaJ; Provisional


Pssm-ID: 184599 [Multi-domain]  Cd Length: 386  Bit Score: 82.93  E-value: 1.59e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30693796  192 CNGCTKKIKIKRDVITSLGEKCEEEEMVEIKVK--PGWKGGTKVTFEGKGNEAMRSVP-ADLTFVIVEKEHEVFKREGDD 268
Cdd:PRK14277 201 CDRCHGEGKIITDPCNKCGGTGRIRRRRKIKVNipAGIDDGQMITLRGEGEPGIKGGPnGDLYIVIKVKPHPLFKREGYN 280

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 30693796  269 LEMAVEVSLLEALTGCELSVALLDGdNMRLRIEDVIHPGYVTVVQGKGMPNLKEKGkRGDLRVRFRTKFPQHLTDEQRA 347
Cdd:PRK14277 281 VYLEMPITFTDAALGGEIEIPTLDG-KVKFTIPEGTQTGTKFRLRGKGIPHLRGRG-RGDQIVKVYIEVPKKLTEKQKE 357
PRK14293 PRK14293
molecular chaperone DnaJ;
188-351 4.34e-17

molecular chaperone DnaJ;


Pssm-ID: 237663 [Multi-domain]  Cd Length: 374  Bit Score: 81.57  E-value: 4.34e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30693796  188 LEELCNGC--------TKKIKIKrdvitslgekceeeemveikVKPGWKGGTKVTFEGKGNEAMRSVPA-DLTFVIVEKE 258
Cdd:PRK14293 199 IEDPCDACggqgvkqvTKKLKIN--------------------IPAGVDTGTRLRVSGEGDAGLRGGPPgDLYVYLFVKN 258

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30693796  259 HEVFKREGDDLEMAVEVSLLEALTGCELSVALLDGdNMRLRIEDVIHPGYVTVVQGKGMPNLKEKGKRGDLRVRFRTKFP 338
Cdd:PRK14293 259 DPEFRRDGINILSEIKISYLQAILGDTLEVDTVDG-PVELTIPAGTQPNTVLTLENKGVPRLGNPVARGDHLITVKVKIP 337

                        170
                 ....*....|....*....
gi 30693796  339 QHLTDEQR------AEIHS 351
Cdd:PRK14293 338 TRISDEERelleklAKIKG 356
PRK14282 PRK14282
chaperone protein DnaJ; Provisional
 190-346 2.39e-16

chaperone protein DnaJ; Provisional


Pssm-ID: 184603 [Multi-domain]  Cd Length: 369  Bit Score: 79.45  E-value: 2.39e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30693796  190 ELCNGCTKKIKIKRDVITSlgekceeeemveIKVKPGWKGGTKVTFEGKGNEAMRSVP-ADLTFVIVEKEHEVFKREGDD 268
Cdd:PRK14282 210 EYCHECGGSGRIRRRVRTT------------VKIPAGVEDGTVLRITGGGNAGYYGGPyGDLYVIVRVRPDPRFKRSGSD 277

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 30693796  269 LEMAVEVSLLEALTGCELSVALLDGDNMRLRIEDVIHPGYVTVVQGKGMPNLkEKGKRGDLRVRFRTKFPQHLTDEQR 346
Cdd:PRK14282 278 LIYDVTIDYLQAILGTTVEVPLPEGGTTMLKIPPGTQPETVFRLKGKGLPNM-RYGRRGDLIVNVHVEIPKRLSREER 354
PRK14284 PRK14284
chaperone protein DnaJ; Provisional
 221-346 1.06e-15

chaperone protein DnaJ; Provisional


Pssm-ID: 237658 [Multi-domain]  Cd Length: 391  Bit Score: 77.58  E-value: 1.06e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30693796  221 IKVKPGWKGGTKVTFEGKGNEAMRSVPA-DLTFVIVEKEHEVFKREGDDLEMAVEVSLLEALTGCELSV-ALLDGDNMRL 298
Cdd:PRK14284 231 VHIPAGVDSGMRLKMEGYGDAGQNGAPAgDLYVFIDVEPHPVFERRGDDLILELPIGFVDAALGMKKEIpTLLKEGTCRL 310

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 30693796  299 RIEDVIHPGYVTVVQGKGMPNLKEKGkRGDLRVRFRTKFPQHLTDEQR 346
Cdd:PRK14284 311 TIPEGIQSGTILKVRGQGFPNVHGKG-RGDLLVRISVETPQNLSEEQK 357
PRK14295 PRK14295
molecular chaperone DnaJ;
221-347 1.26e-15

molecular chaperone DnaJ;


Pssm-ID: 237665 [Multi-domain]  Cd Length: 389  Bit Score: 77.20  E-value: 1.26e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30693796  221 IKVKPGWKGGTKVTFEGKGNEAMRSVPA-DLTFVIVEKEHEVFKREGDDLEMAVEVSLLEALTGCELSVALLDGDNMRLR 299
Cdd:PRK14295 239 VRIPAGVSDGQRIRLRGKGAPGERGGPAgDLYVVVHVDPHPVFGRSGDNLTVTVPVTFPEAALGAEVRVPTLGGPPVTVK 318

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 30693796  300 IEDVIHPGYVTVVQGKGMPnlKEKGKRGDLRVRFRTKFPQHLTDEQRA 347
Cdd:PRK14295 319 LPPGTPNGRVLRVRGKGAV--RKDGTRGDLLVTVEVAVPKDLSGKARE 364
PRK14279 PRK14279
molecular chaperone DnaJ;
221-345 3.15e-15

molecular chaperone DnaJ;


Pssm-ID: 237655 [Multi-domain]  Cd Length: 392  Bit Score: 75.92  E-value: 3.15e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30693796  221 IKVKPGWKGGTKVTFEGKGNEAMRSVPADLTFVIVE-KEHEVFKREGDDLEMAVEVSLLEALTGCELSVALLDGdNMRLR 299
Cdd:PRK14279 246 VRIPPGVEDGQRIRLAGQGEAGLRGAPSGDLYVTVHvRPDKVFGRDGDDLTVTVPVSFTELALGSTLSVPTLDG-PVGVK 324

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 30693796  300 IEDVIHPGYVTVVQGKGMPnlKEKGKRGDLRVRFRTKFPQHLTDEQ 345
Cdd:PRK14279 325 VPAGTADGRILRVRGRGVP--KRSGGAGDLLVTVKVAVPPNLDGAA 368
PRK14289 PRK14289
molecular chaperone DnaJ;
221-357 1.98e-14

molecular chaperone DnaJ;


Pssm-ID: 237660 [Multi-domain]  Cd Length: 386  Bit Score: 73.71  E-value: 1.98e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30693796  221 IKVKPGWKGGTKVTFEGKGNEAMRS-VPADLTFVIVEKEHEVFKREGDDLEMAVEVSLLEALTGCELSVALLDGdNMRLR 299
Cdd:PRK14289 231 VKIPAGVAEGMQLSMNGKGNAGKHGgVNGDLLVVIEEEPHPELIRDENDLIYNLLLSVPTAALGGAVEVPTIDG-KAKVK 309

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 30693796  300 IEDVIHPGYVTVVQGKGMPNLKEKGkRGDLRVRFRTKFPQHLTDEQRaEIHSILQDSS 357
Cdd:PRK14289 310 IEAGTQPGKVLRLRNKGLPSVNGYG-TGDLLVNVSVYIPETLSKEEK-QTLEKMENSD 365
PRK14281 PRK14281
chaperone protein DnaJ; Provisional
 221-346 2.90e-13

chaperone protein DnaJ; Provisional


Pssm-ID: 237657 [Multi-domain]  Cd Length: 397  Bit Score: 70.22  E-value: 2.90e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30693796  221 IKVKPGWKGGTKVTFEGKGNEAMRS-VPADLTFVIVEKEHEVFKREGDDLEMAVEVSLLEALTGCELSVALLDGdNMRLR 299
Cdd:PRK14281 239 VTVPAGVQDGNYLTLRGQGNAGPRGgAPGDLIVVIEEKPHELFVRNGDDVIYNLAVSYPDLVLGTKVEVPTLDG-AVKLT 317

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 30693796  300 IEDVIHPGYVTVVQGKGMPNLKEKGkRGDLRVRFRTKFPQHLTDEQR 346
Cdd:PRK14281 318 IPAGTQPETMLRIPGKGIGHLRGSG-RGDQYVRVNVFVPKEVSHQDK 363
PRK14283 PRK14283
chaperone protein DnaJ; Provisional
 188-346 4.84e-13

chaperone protein DnaJ; Provisional


Pssm-ID: 184604 [Multi-domain]  Cd Length: 378  Bit Score: 69.47  E-value: 4.84e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30693796  188 LEELCNGCTKKIKIKRDVITSlgekceeeemveIKVKPGWKGGTKVTFEGKGNEAMR-SVPADLTFVIVEKEHEVFKREG 266
Cdd:PRK14283 202 VEKPCSNCHGKGVVRETKTIS------------VKIPAGVETGSRLRVSGEGEMGDRgGEPGDLYVVIKVKPHKIFRREG 269

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30693796  267 DDLEMAVEVSLLEALTGCELSVALLDGDnMRLRIEDVIHPGYVTVVQGKGMPNLKEKGKrGDLRVRFRTKFPQHLTDEQR 346
Cdd:PRK14283 270 ANLYYEKPISFVQAALGDTVDVPTIDGP-VELKIPAGTQSGTTFRLKGHGMPSLRWSGK-GNLYVKVKVVVPKKLSPKQK 347
PRK14280 PRK14280
molecular chaperone DnaJ;
192-346 8.61e-13

molecular chaperone DnaJ;


Pssm-ID: 237656 [Multi-domain]  Cd Length: 376  Bit Score: 68.59  E-value: 8.61e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30693796  192 CNGCTKKIKIKrdvITSLGEKCEEEEMVEIKVK--PGWKGGTKVTFEGKGNEAMRSVPA-DLTFVIVEKEHEVFKREGDD 268
Cdd:PRK14280 192 CNGTGQEIKEK---CPTCHGKGKVRKRKKINVKipAGVDNGQQIRVSGEGEPGVNGGPAgDLYVVFRVRPHEFFERDGDD 268

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 30693796  269 LEMAVEVSLLEALTGCELSVALLDGdNMRLRIEDVIHPGYVTVVQGKGMPNLKEKGkRGDLRVRFRTKFPQHLTDEQR 346
Cdd:PRK14280 269 IYCEMPLTFAQAALGDEIEVPTLHG-KVKLKIPAGTQTGTQFRLKGKGVPNVRGYG-QGDQYVVVRVVTPTKLTDRQK 344
PRK14298 PRK14298
chaperone protein DnaJ; Provisional
 190-346 2.00e-12

chaperone protein DnaJ; Provisional


Pssm-ID: 184612 [Multi-domain]  Cd Length: 377  Bit Score: 67.57  E-value: 2.00e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30693796  190 ELCNGcTKKIKIKRDVitslgekceeeemvEIKVKPGWKGGTKVTFEGKGNEAMRSVPA-DLTFVIVEKEHEVFKREGDD 268
Cdd:PRK14298 202 PVCSG-TGKVRKTRKI--------------TVNVPAGADSGLRLKLSGEGEAGSPGAPSgDLYIVLHVKEHDYFERVGDD 266

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 30693796  269 LEMAVEVSLLEALTGCELSVALLDGD-NMRLRIEDVIHPgyVTVVQGKGMPNLKEKGKrGDLRVRFRTKFPQHLTDEQR 346
Cdd:PRK14298 267 IISEIPISFTQAALGADIMVPTLYGKvKMNIPPGTQTHS--VFRLKDKGMPRLHGHGK-GDQLVKVIVKTPTKLTQEQK 342
PRK14296 PRK14296
chaperone protein DnaJ; Provisional
 192-357 2.71e-12

chaperone protein DnaJ; Provisional


Pssm-ID: 237666 [Multi-domain]  Cd Length: 372  Bit Score: 67.28  E-value: 2.71e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30693796  192 CNGCTKKIKIKRDVITSLGEKCEEEEMVeIKVKPGWKGGTKVTFEGKGNEAMRS-VPADLTFVIVEKEHEVFKR-EGDDL 269
Cdd:PRK14296 198 CNGAGKIIKNKCKNCKGKGKYLERKKIE-VNIPKGIRPNQQIKLSQKGHASLNNgVNGDLIIDIYLKESKVFEIiNNNDI 276

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30693796  270 EMAVEVSLLEALTGCELSVALLDGDnMRLRIEDVIHPGYVTVVQGKGMPNLKEKGKRGDLRVRFRTKFPQHLTDEQRAEI 349
Cdd:PRK14296 277 LMTYNISYLDAILGNEIIIKTLDGD-IKYKLPKSINSNELIIINNKGLYKSINKDKRGDLIIKVNIVVPKNLSKKEKELI 355


                 ....*...
gi 30693796  350 HSILQDSS 357
Cdd:PRK14296 356 EQIYEQTS 363
PRK14287 PRK14287
chaperone protein DnaJ; Provisional
 185-356 3.24e-12

chaperone protein DnaJ; Provisional


Pssm-ID: 237659 [Multi-domain]  Cd Length: 371  Bit Score: 66.96  E-value: 3.24e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30693796  185 RCTLEELCNGCTKKIKIKRDVITSLGEKCEEEEMVEIKVK--PGWKGGTKVTFEGKGNEAMRSVPA-DLTFVIVEKEHEV 261
Cdd:PRK14287 177 RVVNRRVCHHCEGTGKIIKQKCATCGGKGKVRKRKKINVKvpAGIDHGQQLRVSGQGEAGVNGGPPgDLYVVFNVKPHEF 256

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30693796  262 FKREGDDLEMAVEVSLLEALTGCELSVALLDGdNMRLRIEDVIHPGYVTVVQGKGMPNLKEKGKrGDLRVRFRTKFPQHL 341
Cdd:PRK14287 257 FERDGDDIYCEMPLTFPQVALGDEIEVPTLNG-KVKLKIPAGTQTGTSFRLRGKGVPNVHGRGQ-GDQHVQVRVVTPKNL 334

                        170
                 ....*....|....*
gi 30693796  342 TDEQRAEIHSILQDS 356
Cdd:PRK14287 335 TEKEKELMREFAGMS 349
PRK14299 PRK14299
chaperone protein DnaJ; Provisional
 181-347 2.36e-11

chaperone protein DnaJ; Provisional


Pssm-ID: 237667 [Multi-domain]  Cd Length: 291  Bit Score: 63.80  E-value: 2.36e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30693796  181 EKKLRCTLEELCNGCTKKIKIKRDVITslgekceeeemveIKVKPGWKGGTKVTFEGKGNEAmrsvpADLTFVIVEKEHE 260
Cdd:PRK14299 133 EAELPLTLEEAYRGGEKVVEVAGERLS-------------VRIPPGVREGQVIRLAGKGRQG-----GDLYLVVRLLPHP 194

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30693796  261 VFKREGDDLEMAVEVSLLEALTGCELSVALLDGDnMRLRIEDVIHPGYVTVVQGKGMPNlKEKGkRGDLRVRFRTKFPQH 340
Cdd:PRK14299 195 VFRLEGDDLYATVDVPAPIAVVGGKVRVMTLDGP-VEVTIPPRTQAGRKLRLKGKGWPR-GPAG-RGDQYAEVRITIPTR 271


                 ....*..
gi 30693796  341 LTDEQRA 347
Cdd:PRK14299 272 PTPEEER 278
PRK14294 PRK14294
chaperone protein DnaJ; Provisional
 221-347 2.47e-11

chaperone protein DnaJ; Provisional


Pssm-ID: 237664 [Multi-domain]  Cd Length: 366  Bit Score: 64.40  E-value: 2.47e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30693796  221 IKVKPGWKGGTKVTFEGKGNEAMRS-VPADLTFVIVEKEHEVFKREGDDLEMAVEVSLLEALTGCELSVALLDGDNmRLR 299
Cdd:PRK14294 217 VKIPAGVDTGSRLRLRGEGEAGVRGgPPGDLYVFLTVEPHEFFERDGNDVHCKVPISFVQAALGAQIEVPTLEGER-ELK 295

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 30693796  300 IEDVIHPGYVTVVQGKGMPNLKEKGkRGDLRVRFRTKFPQHLTDEQRA 347
Cdd:PRK14294 296 IPKGTQPGDIFRFKGKGIPSLRGGG-RGDQIIEVEVKVPTRLTKKQEE 342
PRK14292 PRK14292
chaperone protein DnaJ; Provisional
 189-351 3.41e-11

chaperone protein DnaJ; Provisional


Pssm-ID: 237662 [Multi-domain]  Cd Length: 371  Bit Score: 63.75  E-value: 3.41e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30693796  189 EELCNGCTKKIKIKRDVITSLGEKCEEEEMVEIKVK--PGWKGGTKVTFEGKGNEAMRSvPADLTFVIVEKEHEVFKREG 266
Cdd:PRK14292 183 QQPCPTCRGEGQIITDPCTVCRGRGRTLKAETVKVKlpRGIDEGYRIRVAGMGNEGPGG-NGDLYVHIEMEPHPELRREQ 261

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30693796  267 DDLEMAVEVSLLEALTGCELSVALLDGDNMrLRIEDVIHPGYVTVVQGKGMPNLKEKGKrGDLRVRFRTKFPQHLTDEQR 346
Cdd:PRK14292 262 EHLIYEARIGFAKAALGGQITVPTLDGPQV-IEVKPGTQHGDLHRLRGQGMPRLQGAGT-GDLIVEYEIAVPKQLSPEAR 339


                 ....*
gi 30693796  347 AEIHS 351
Cdd:PRK14292 340 EALEA 344
PRK14297 PRK14297
molecular chaperone DnaJ;
192-356 1.10e-10

molecular chaperone DnaJ;


Pssm-ID: 184611 [Multi-domain]  Cd Length: 380  Bit Score: 62.49  E-value: 1.10e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30693796  192 CNGCTKKIKIKRDVITSLGEKCEEEEMVEIKVK--PGWKGGTKVTFEGKGNEAMRSVPA-DLTFVIVEKEHEVFKREGDD 268
Cdd:PRK14297 194 CDKCGGSGKVIEDPCNKCHGKGKVRKNRKIKVNvpAGVDTGNVIPLRGQGEHGKNGGPTgDLYINIRVAPHKTFKRKGFD 273

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30693796  269 LEMAVEVSLLEALTGCELSVALLDGDnMRLRIEDVIHPGYVTVVQGKGMPNLKEKGkRGDLRVRFRTKFPQHLTDEQRAE 348
Cdd:PRK14297 274 IYIDKHISFAKAALGTEIKVPTVDGE-VKYEVPAGTQPGTVFRLKGKGVPRVNSTG-RGNQYVTVIVDIPKKLNSKQKEA 351


                 ....*...
gi 30693796  349 IHSILQDS 356
Cdd:PRK14297 352 LTMFMEAS 359
PRK14290 PRK14290
chaperone protein DnaJ; Provisional
 192-352 1.63e-10

chaperone protein DnaJ; Provisional


Pssm-ID: 172778 [Multi-domain]  Cd Length: 365  Bit Score: 61.87  E-value: 1.63e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30693796  192 CNGCTKKIKIKRDVITSLGEKCEEEEMVEIKVK-PgwKGGT---KVTFEGKGNeAMRSVPADLTFVIVEKEHEVFKREGD 267
Cdd:PRK14290 194 CRTCGGRGRIPEEKCPRCNGTGTVVVNEDISVKiP--KGATdnlRLRVKGKGQ-SYGGRTGDLYVVLRVNNDPNIQRIND 270

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30693796  268 DLEMAVEVSLLEALTGCELSVALLDgDNMRLRIEDVIHPGYVTVVQGKGMPNLKEKGKrGDLRVRFRTKFPQHLTDEQRA 347
Cdd:PRK14290 271 DLYVDQKINFPQAALGGEIEIKLFR-EKYNLKIPEGTQPGEVLKIKGAGMPHLNGHGS-GDLLVRINVEVPKRLTSKQKE 348


                 ....*
gi 30693796  348 EIHSI 352
Cdd:PRK14290 349 LIREF 353
PRK14300 PRK14300
chaperone protein DnaJ; Provisional
 221-356 1.50e-08

chaperone protein DnaJ; Provisional


Pssm-ID: 172788 [Multi-domain]  Cd Length: 372  Bit Score: 55.79  E-value: 1.50e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30693796  221 IKVKPGWKGGTKVTFEGKGNEAMRS-VPADLTFVIVEKEHEVFKREGDDLEMAVEVSLLEALTGCELSVALLDGDNMRLR 299
Cdd:PRK14300 218 VNIPAGVENGTRIRHTGEGEAGIRGgNSGDLYVDIAIKPHDIYKVDGANLHCKLPISFVNAALGGEIEVPVIEGGKVNLT 297

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 30693796  300 IEDVIHPGYVTVVQGKGMPNLKEKgKRGDLRVRFRTKFPQHLTDEQRAEIHSILQDS 356
Cdd:PRK14300 298 IPAGTQNGDQLRLRSKGMSKMRST-IRGDMLTHIHVEVPKNLSKRQRELLEEFKKES 353
PRK14288 PRK14288
molecular chaperone DnaJ;
232-347 1.89e-05

molecular chaperone DnaJ;


Pssm-ID: 172776 [Multi-domain]  Cd Length: 369  Bit Score: 46.22  E-value: 1.89e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30693796  232 KVTFEGKGNEAMRSVPADLTFVIVEKEHEVFKREGDDLEMAVEVSLLEALTGCELSVALLDGDNMRLRIEDVIHPGYVTV 311
Cdd:PRK14288 223 RMVLKNKGNEYEKGKRGDLYLEARVKEDEHFKREGCDLFIEAPVFFTTIALGHTIKVPSLKGDELELKIPRNARDRQTFA 302

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 30693796  312 VQGKGMPNlKEKGKRGDLRVRFRTKFPQHLTDEQRA 347
Cdd:PRK14288 303 FRNEGVKH-PESSYRGSLIVELQVIYPKSLNKEQQE 337
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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