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Conserved domains on  [gi|15217593|ref|NP_174624|]
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Leucine-rich repeat (LRR) family protein [Arabidopsis thaliana]

Protein Classification

leucine-rich repeat domain-containing protein( domain architecture ID 1000136)

leucine-rich repeat (LRR) domain-containing protein may participate in protein-protein interactions

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PLN00113 super family cl33413
leucine-rich repeat receptor-like protein kinase; Provisional
 7-453 2.54e-55

leucine-rich repeat receptor-like protein kinase; Provisional


The actual alignment was detected with superfamily member PLN00113:

Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 198.92  E-value: 2.54e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217593    7 PLFIFAFVIFL---RCLspieaatcHPDDEAGLLAFKSGItQDPTGILSSWKKGTDCCSWKGVGCL-TNRVTGLtingqs 82
Cdd:PLN00113  10 PYLIFMLFFLFlnfSML--------HAEELELLLSFKSSI-NDPLKYLSNWNSSADVCLWQGITCNnSSRVVSI------ 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217593   83 DVTGSFLSGTISPSLAKLQHLVGIYFTNlRNITGSFPQFLFQ-----------------------LPNVKQVYFTNSRLS 139
Cdd:PLN00113  75 DLSGKNISGKISSAIFRLPYIQTINLSN-NQLSGPIPDDIFTtssslrylnlsnnnftgsiprgsIPNLETLDLSNNMLS 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217593  140 GPLPANIGALSELGELSLDGNLFTGPIPSSISNLTRLYLLNLGDNLLTGTIPLGLANLKIL--LSLNFGN---------- 207
Cdd:PLN00113 154 GEIPNDIGSFSSLKVLDLGGNVLVGKIPNSLTNLTSLEFLTLASNQLVGQIPRELGQMKSLkwIYLGYNNlsgeipyeig 233

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217593  208 ------------NRLSETIPDIFKSMQKLQSLTLSRNKFSGNLPPSIASLKPILNyLDLSQNNLSGTIPTFLSNFKVLDS 275
Cdd:PLN00113 234 gltslnhldlvyNNLTGPIPSSLGNLKNLQYLFLYQNKLSGPIPPSIFSLQKLIS-LDLSDNSLSGEIPELVIQLQNLEI 312

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217593  276 LDLSRNRFSGVVPKSLANMPKLFHLNLSHNFLTGPLPA-MKNVDGLATLDLSYNQFHLKtIPKWVTSSPSMYSLKL---- 350
Cdd:PLN00113 313 LHLFSNNFTGKIPVALTSLPRLQVLQLWSNKFSGEIPKnLGKHNNLTVLDLSTNNLTGE-IPEGLCSSGNLFKLILfsns 391

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217593  351 VKCGINMSLDNWKPVRpniyfYIDLSENEISGSLTWFFNLAHNLYEFQASGNKL-------RFDMGKLNL---------- 413
Cdd:PLN00113 392 LEGEIPKSLGACRSLR-----RVRLQDNSFSGELPSEFTKLPLVYFLDISNNNLqgrinsrKWDMPSLQMlslarnkffg 466

                        490       500       510       520       530
                 ....*....|....*....|....*....|....*....|....*....|
gi 15217593  414 -------SERLESLDLSRNLIFGKVP---MTVAKLQKLNLSHNHLCGKLP 453
Cdd:PLN00113 467 glpdsfgSKRLENLDLSRNQFSGAVPrklGSLSELMQLKLSENKLSGEIP 516
 
Name Accession Description Interval E-value
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 7-453 2.54e-55

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 198.92  E-value: 2.54e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217593    7 PLFIFAFVIFL---RCLspieaatcHPDDEAGLLAFKSGItQDPTGILSSWKKGTDCCSWKGVGCL-TNRVTGLtingqs 82
Cdd:PLN00113  10 PYLIFMLFFLFlnfSML--------HAEELELLLSFKSSI-NDPLKYLSNWNSSADVCLWQGITCNnSSRVVSI------ 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217593   83 DVTGSFLSGTISPSLAKLQHLVGIYFTNlRNITGSFPQFLFQ-----------------------LPNVKQVYFTNSRLS 139
Cdd:PLN00113  75 DLSGKNISGKISSAIFRLPYIQTINLSN-NQLSGPIPDDIFTtssslrylnlsnnnftgsiprgsIPNLETLDLSNNMLS 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217593  140 GPLPANIGALSELGELSLDGNLFTGPIPSSISNLTRLYLLNLGDNLLTGTIPLGLANLKIL--LSLNFGN---------- 207
Cdd:PLN00113 154 GEIPNDIGSFSSLKVLDLGGNVLVGKIPNSLTNLTSLEFLTLASNQLVGQIPRELGQMKSLkwIYLGYNNlsgeipyeig 233

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217593  208 ------------NRLSETIPDIFKSMQKLQSLTLSRNKFSGNLPPSIASLKPILNyLDLSQNNLSGTIPTFLSNFKVLDS 275
Cdd:PLN00113 234 gltslnhldlvyNNLTGPIPSSLGNLKNLQYLFLYQNKLSGPIPPSIFSLQKLIS-LDLSDNSLSGEIPELVIQLQNLEI 312

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217593  276 LDLSRNRFSGVVPKSLANMPKLFHLNLSHNFLTGPLPA-MKNVDGLATLDLSYNQFHLKtIPKWVTSSPSMYSLKL---- 350
Cdd:PLN00113 313 LHLFSNNFTGKIPVALTSLPRLQVLQLWSNKFSGEIPKnLGKHNNLTVLDLSTNNLTGE-IPEGLCSSGNLFKLILfsns 391

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217593  351 VKCGINMSLDNWKPVRpniyfYIDLSENEISGSLTWFFNLAHNLYEFQASGNKL-------RFDMGKLNL---------- 413
Cdd:PLN00113 392 LEGEIPKSLGACRSLR-----RVRLQDNSFSGELPSEFTKLPLVYFLDISNNNLqgrinsrKWDMPSLQMlslarnkffg 466

                        490       500       510       520       530
                 ....*....|....*....|....*....|....*....|....*....|
gi 15217593  414 -------SERLESLDLSRNLIFGKVP---MTVAKLQKLNLSHNHLCGKLP 453
Cdd:PLN00113 467 glpdsfgSKRLENLDLSRNQFSGAVPrklGSLSELMQLKLSENKLSGEIP 516
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
36-328 3.52e-22

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 98.47  E-value: 3.52e-22
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217593  36 LLAFKSGITQDPTGILSSWKKGTDCCSWKGVGCLTNRVTGLTINGQSDVTGSFLSGTISPSLAKLQHLVGI-YFTNLRNI 114
Cdd:COG4886  39 LLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGNEELsNLTNLESL 118

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217593 115 T------GSFPQFLFQLPNVKQVYFTNSRLSgPLPANIGALSELGELSLDGNLFTGpIPSSISNLTRLYLLNLGDNLLTg 188
Cdd:COG4886 119 DlsgnqlTDLPEELANLTNLKELDLSNNQLT-DLPEPLGNLTNLKSLDLSNNQLTD-LPEELGNLTNLKELDLSNNQIT- 195

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217593 189 TIPLGLANLKILLSLNFGNNRLSEtIPDIFKSMQKLQSLTLSRNKFSGnlPPSIASLkPILNYLDLSQNNLSgTIPtFLS 268
Cdd:COG4886 196 DLPEPLGNLTNLEELDLSGNQLTD-LPEPLANLTNLETLDLSNNQLTD--LPELGNL-TNLEELDLSNNQLT-DLP-PLA 269

                       250       260       270       280       290       300
                ....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217593 269 NFKVLDSLDLSRNRFSGVVPKSLANMPKLFHLNLSHNFLTGPLPAMKNVDGLATLDLSYN 328
Cdd:COG4886 270 NLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLL 329
LRRNT_2 pfam08263
Leucine rich repeat N-terminal domain; Leucine Rich Repeats pfam00560 are short sequence ...
 29-68 6.57e-10

Leucine rich repeat N-terminal domain; Leucine Rich Repeats pfam00560 are short sequence motifs present in a number of proteins with diverse functions and cellular locations. Leucine Rich Repeats are often flanked by cysteine rich domains. This domain is often found at the N-terminus of tandem leucine rich repeats.


Pssm-ID: 462411 [Multi-domain]  Cd Length: 41  Bit Score: 54.22  E-value: 6.57e-10
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 15217593    29 HPDDEAGLLAFKSGITqDPTGILSSWK-KGTDCCSWKGVGC 68
Cdd:pfam08263   1 LNDDGQALLAFKSSLN-DPPGALSSWNsSSSDPCSWTGVTC 40
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 168-305 2.41e-09

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 57.49  E-value: 2.41e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217593 168 SSISNLTRLYLLNlgdNLLTgTIPlGLANLKILLSLNFGNNRLSEtipdI--FKSMQKLQSLTLSRNkfsgNLPP----- 240
Cdd:cd21340  43 EFLTNLTHLYLQN---NQIE-KIE-NLENLVNLKKLYLGGNRISV----VegLENLTNLEELHIENQ----RLPPgeklt 109

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 15217593 241 ----SIASLKPILNYLDLSQNNLsgTIPTFLSNFKVLDSLDLSRNRFSGV--VPKSLANMPKLFHLNLSHN 305
Cdd:cd21340 110 fdprSLAALSNSLRVLNISGNNI--DSLEPLAPLRNLEQLDASNNQISDLeeLLDLLSSWPSLRELDLTGN 178
 
Name Accession Description Interval E-value
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 7-453 2.54e-55

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 198.92  E-value: 2.54e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217593    7 PLFIFAFVIFL---RCLspieaatcHPDDEAGLLAFKSGItQDPTGILSSWKKGTDCCSWKGVGCL-TNRVTGLtingqs 82
Cdd:PLN00113  10 PYLIFMLFFLFlnfSML--------HAEELELLLSFKSSI-NDPLKYLSNWNSSADVCLWQGITCNnSSRVVSI------ 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217593   83 DVTGSFLSGTISPSLAKLQHLVGIYFTNlRNITGSFPQFLFQ-----------------------LPNVKQVYFTNSRLS 139
Cdd:PLN00113  75 DLSGKNISGKISSAIFRLPYIQTINLSN-NQLSGPIPDDIFTtssslrylnlsnnnftgsiprgsIPNLETLDLSNNMLS 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217593  140 GPLPANIGALSELGELSLDGNLFTGPIPSSISNLTRLYLLNLGDNLLTGTIPLGLANLKIL--LSLNFGN---------- 207
Cdd:PLN00113 154 GEIPNDIGSFSSLKVLDLGGNVLVGKIPNSLTNLTSLEFLTLASNQLVGQIPRELGQMKSLkwIYLGYNNlsgeipyeig 233

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217593  208 ------------NRLSETIPDIFKSMQKLQSLTLSRNKFSGNLPPSIASLKPILNyLDLSQNNLSGTIPTFLSNFKVLDS 275
Cdd:PLN00113 234 gltslnhldlvyNNLTGPIPSSLGNLKNLQYLFLYQNKLSGPIPPSIFSLQKLIS-LDLSDNSLSGEIPELVIQLQNLEI 312

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217593  276 LDLSRNRFSGVVPKSLANMPKLFHLNLSHNFLTGPLPA-MKNVDGLATLDLSYNQFHLKtIPKWVTSSPSMYSLKL---- 350
Cdd:PLN00113 313 LHLFSNNFTGKIPVALTSLPRLQVLQLWSNKFSGEIPKnLGKHNNLTVLDLSTNNLTGE-IPEGLCSSGNLFKLILfsns 391

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217593  351 VKCGINMSLDNWKPVRpniyfYIDLSENEISGSLTWFFNLAHNLYEFQASGNKL-------RFDMGKLNL---------- 413
Cdd:PLN00113 392 LEGEIPKSLGACRSLR-----RVRLQDNSFSGELPSEFTKLPLVYFLDISNNNLqgrinsrKWDMPSLQMlslarnkffg 466

                        490       500       510       520       530
                 ....*....|....*....|....*....|....*....|....*....|
gi 15217593  414 -------SERLESLDLSRNLIFGKVP---MTVAKLQKLNLSHNHLCGKLP 453
Cdd:PLN00113 467 glpdsfgSKRLENLDLSRNQFSGAVPrklGSLSELMQLKLSENKLSGEIP 516
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 83-331 3.34e-36

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 142.68  E-value: 3.34e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217593   83 DVTGSFLSGTISPSLAKLQHLVGIY-FTNlrNITGSFPQFLFQLPNVKQVYFTNSRLSGPLPANIGALSELGELSLDGNL 161
Cdd:PLN00113 290 DLSDNSLSGEIPELVIQLQNLEILHlFSN--NFTGKIPVALTSLPRLQVLQLWSNKFSGEIPKNLGKHNNLTVLDLSTNN 367

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217593  162 FTGPIPSSI---SNLTRLYLLN---------------------LGDNLLTGTIPLGLANLKILLSLNFGNNRLSETIPDI 217
Cdd:PLN00113 368 LTGEIPEGLcssGNLFKLILFSnslegeipkslgacrslrrvrLQDNSFSGELPSEFTKLPLVYFLDISNNNLQGRINSR 447

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217593  218 FKSMQKLQSLTLSRNKFSGNLPPSIASLK----------------------PILNYLDLSQNNLSGTIPTFLSNFKVLDS 275
Cdd:PLN00113 448 KWDMPSLQMLSLARNKFFGGLPDSFGSKRlenldlsrnqfsgavprklgslSELMQLKLSENKLSGEIPDELSSCKKLVS 527

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 15217593  276 LDLSRNRFSGVVPKSLANMPKLFHLNLSHNFLTGPLPA-MKNVDGLATLDLSYNQFH 331
Cdd:PLN00113 528 LDLSHNQLSGQIPASFSEMPVLSQLDLSQNQLSGEIPKnLGNVESLVQVNISHNHLH 584
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 89-312 2.43e-31

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 128.04  E-value: 2.43e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217593   89 LSGTISPSLAKLQHLVGIYFTNlRNITGSFPQFLFQLPNV-KQVYFTNSrLSGPLPANIGALSELGELSLDGNLFTGPIP 167
Cdd:PLN00113 344 FSGEIPKNLGKHNNLTVLDLST-NNLTGEIPEGLCSSGNLfKLILFSNS-LEGEIPKSLGACRSLRRVRLQDNSFSGELP 421

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217593  168 SSISNLTRLYLLNLGDNLLTGTIP-----------LGLANLKI------------LLSLNFGNNRLSETIPDIFKSMQKL 224
Cdd:PLN00113 422 SEFTKLPLVYFLDISNNNLQGRINsrkwdmpslqmLSLARNKFfgglpdsfgskrLENLDLSRNQFSGAVPRKLGSLSEL 501

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217593  225 QSLTLSRNKFSGNLPPSIASLKPILNyLDLSQNNLSGTIPTFLSNFKVLDSLDLSRNRFSGVVPKSLANMPKLFHLNLSH 304
Cdd:PLN00113 502 MQLKLSENKLSGEIPDELSSCKKLVS-LDLSHNQLSGQIPASFSEMPVLSQLDLSQNQLSGEIPKNLGNVESLVQVNISH 580


                 ....*...
gi 15217593  305 NFLTGPLP 312
Cdd:PLN00113 581 NHLHGSLP 588
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 89-292 7.23e-26

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 111.48  E-value: 7.23e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217593   89 LSGTISPSLAKLQHLVGIYFTNlRNITGSFPQFLFQLPNVKQVYFTNSRLSGPLPANIGALSELGELSLDGNLFTGPIPS 168
Cdd:PLN00113 392 LEGEIPKSLGACRSLRRVRLQD-NSFSGELPSEFTKLPLVYFLDISNNNLQGRINSRKWDMPSLQMLSLARNKFFGGLPD 470

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217593  169 SiSNLTRLYLLNLGDNLLTGTIPLGLANLKILLSLNFGNNRLSETIPDIFKSMQKLQSLTLSRNKFSGNLPPSIASLkPI 248
Cdd:PLN00113 471 S-FGSKRLENLDLSRNQFSGAVPRKLGSLSELMQLKLSENKLSGEIPDELSSCKKLVSLDLSHNQLSGQIPASFSEM-PV 548

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 15217593  249 LNYLDLSQNNLSGTIPTFLSNFKVLDSLDLSRNRFSGVVPKSLA 292
Cdd:PLN00113 549 LSQLDLSQNQLSGEIPKNLGNVESLVQVNISHNHLHGSLPSTGA 592
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
36-328 3.52e-22

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 98.47  E-value: 3.52e-22
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217593  36 LLAFKSGITQDPTGILSSWKKGTDCCSWKGVGCLTNRVTGLTINGQSDVTGSFLSGTISPSLAKLQHLVGI-YFTNLRNI 114
Cdd:COG4886  39 LLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGNEELsNLTNLESL 118

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217593 115 T------GSFPQFLFQLPNVKQVYFTNSRLSgPLPANIGALSELGELSLDGNLFTGpIPSSISNLTRLYLLNLGDNLLTg 188
Cdd:COG4886 119 DlsgnqlTDLPEELANLTNLKELDLSNNQLT-DLPEPLGNLTNLKSLDLSNNQLTD-LPEELGNLTNLKELDLSNNQIT- 195

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217593 189 TIPLGLANLKILLSLNFGNNRLSEtIPDIFKSMQKLQSLTLSRNKFSGnlPPSIASLkPILNYLDLSQNNLSgTIPtFLS 268
Cdd:COG4886 196 DLPEPLGNLTNLEELDLSGNQLTD-LPEPLANLTNLETLDLSNNQLTD--LPELGNL-TNLEELDLSNNQLT-DLP-PLA 269

                       250       260       270       280       290       300
                ....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217593 269 NFKVLDSLDLSRNRFSGVVPKSLANMPKLFHLNLSHNFLTGPLPAMKNVDGLATLDLSYN 328
Cdd:COG4886 270 NLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLL 329
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
81-336 9.69e-21

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 94.23  E-value: 9.69e-21
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217593  81 QSDVTGSFLSGTISPSLAKLQHLVGIYFTNLRNITGSFPQFLFQLPNVKQVYFTNSRLSGPLPANIGALSE-LGELSLDG 159
Cdd:COG4886   2 LLLLLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLlLLLLSLLL 81

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217593 160 NLFTGPIPSSISNLTRLYLLNLGDNLltgtiplGLANLKILLSLNFGNNRLSEtIPDIFKSMQKLQSLTLSRNKFSgNLP 239
Cdd:COG4886  82 LSLLLLGLTDLGDLTNLTELDLSGNE-------ELSNLTNLESLDLSGNQLTD-LPEELANLTNLKELDLSNNQLT-DLP 152

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217593 240 PSIASLKPiLNYLDLSQNNLSgTIPTFLSNFKVLDSLDLSRNRFSgVVPKSLANMPKLFHLNLSHNFLTGPLPAMKNVDG 319
Cdd:COG4886 153 EPLGNLTN-LKSLDLSNNQLT-DLPEELGNLTNLKELDLSNNQIT-DLPEPLGNLTNLEELDLSGNQLTDLPEPLANLTN 229

                       250
                ....*....|....*..
gi 15217593 320 LATLDLSYNQfhLKTIP 336
Cdd:COG4886 230 LETLDLSNNQ--LTDLP 244
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 83-245 9.93e-17

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 83.36  E-value: 9.93e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217593   83 DVTGSFLSGTIS------PSLAKLQHLVGIYFTNLRNITGSfpqflfqlPNVKQVYFTNSRLSGPLPANIGALSELGELS 156
Cdd:PLN00113 434 DISNNNLQGRINsrkwdmPSLQMLSLARNKFFGGLPDSFGS--------KRLENLDLSRNQFSGAVPRKLGSLSELMQLK 505

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217593  157 LDGNLFTGPIPSSISNLTRLYLLNLGDNLLTGTIPLGLANLKILLSLNFGNNRLSETIPDIFKSMQKLQSLTLSRNKFSG 236
Cdd:PLN00113 506 LSENKLSGEIPDELSSCKKLVSLDLSHNQLSGQIPASFSEMPVLSQLDLSQNQLSGEIPKNLGNVESLVQVNISHNHLHG 585


                 ....*....
gi 15217593  237 NLPPSIASL 245
Cdd:PLN00113 586 SLPSTGAFL 594
PLN03150 PLN03150
hypothetical protein; Provisional
 203-295 5.27e-13

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 71.00  E-value: 5.27e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217593  203 LNFGNNRLSETIPDIFKSMQKLQSLTLSRNKFSGNLPPSIASLkPILNYLDLSQNNLSGTIPTFLSNFKVLDSLDLSRNR 282
Cdd:PLN03150 423 LGLDNQGLRGFIPNDISKLRHLQSINLSGNSIRGNIPPSLGSI-TSLEVLDLSYNSFNGSIPESLGQLTSLRILNLNGNS 501

                         90
                 ....*....|...
gi 15217593  283 FSGVVPKSLANMP 295
Cdd:PLN03150 502 LSGRVPAALGGRL 514
PLN03150 PLN03150
hypothetical protein; Provisional
 63-208 3.54e-10

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 62.14  E-value: 3.54e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217593   63 WKGVGCLTNR------VTGLTINGQSdvtgsfLSGTISPSLAKLQHLVGIyftNLrnitgsfpqflfqlpnvkqvyfTNS 136
Cdd:PLN03150 404 WSGADCQFDStkgkwfIDGLGLDNQG------LRGFIPNDISKLRHLQSI---NL----------------------SGN 452

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 15217593  137 RLSGPLPANIGALSELGELSLDGNLFTGPIPSSISNLTRLYLLNLGDNLLTGTIPLGLANLKIL-LSLNFGNN 208
Cdd:PLN03150 453 SIRGNIPPSLGSITSLEVLDLSYNSFNGSIPESLGQLTSLRILNLNGNSLSGRVPAALGGRLLHrASFNFTDN 525
PLN03150 PLN03150
hypothetical protein; Provisional
 155-253 4.33e-10

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 62.14  E-value: 4.33e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217593  155 LSLDGNLFTGPIPSSISNLTRLYLLNLGDNLLTGTIPLGLANLKILLSLNFGNNRLSETIPDIFKSMQKLQSLTLSRNKF 234
Cdd:PLN03150 423 LGLDNQGLRGFIPNDISKLRHLQSINLSGNSIRGNIPPSLGSITSLEVLDLSYNSFNGSIPESLGQLTSLRILNLNGNSL 502

                         90       100
                 ....*....|....*....|..
gi 15217593  235 SGNLPPSIASL---KPILNYLD 253
Cdd:PLN03150 503 SGRVPAALGGRllhRASFNFTD 524
LRRNT_2 pfam08263
Leucine rich repeat N-terminal domain; Leucine Rich Repeats pfam00560 are short sequence ...
 29-68 6.57e-10

Leucine rich repeat N-terminal domain; Leucine Rich Repeats pfam00560 are short sequence motifs present in a number of proteins with diverse functions and cellular locations. Leucine Rich Repeats are often flanked by cysteine rich domains. This domain is often found at the N-terminus of tandem leucine rich repeats.


Pssm-ID: 462411 [Multi-domain]  Cd Length: 41  Bit Score: 54.22  E-value: 6.57e-10
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 15217593    29 HPDDEAGLLAFKSGITqDPTGILSSWK-KGTDCCSWKGVGC 68
Cdd:pfam08263   1 LNDDGQALLAFKSSLN-DPPGALSSWNsSSSDPCSWTGVTC 40
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 168-305 2.41e-09

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 57.49  E-value: 2.41e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217593 168 SSISNLTRLYLLNlgdNLLTgTIPlGLANLKILLSLNFGNNRLSEtipdI--FKSMQKLQSLTLSRNkfsgNLPP----- 240
Cdd:cd21340  43 EFLTNLTHLYLQN---NQIE-KIE-NLENLVNLKKLYLGGNRISV----VegLENLTNLEELHIENQ----RLPPgeklt 109

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 15217593 241 ----SIASLKPILNYLDLSQNNLsgTIPTFLSNFKVLDSLDLSRNRFSGV--VPKSLANMPKLFHLNLSHN 305
Cdd:cd21340 110 fdprSLAALSNSLRVLNISGNNI--DSLEPLAPLRNLEQLDASNNQISDLeeLLDLLSSWPSLRELDLTGN 178
PLN03150 PLN03150
hypothetical protein; Provisional
 135-215 3.28e-09

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 59.06  E-value: 3.28e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217593  135 NSRLSGPLPANIGALSELGELSLDGNLFTGPIPSSISNLTRLYLLNLGDNLLTGTIPLGLANLKILLSLNFGNNRLSETI 214
Cdd:PLN03150 427 NQGLRGFIPNDISKLRHLQSINLSGNSIRGNIPPSLGSITSLEVLDLSYNSFNGSIPESLGQLTSLRILNLNGNSLSGRV 506


                 .
gi 15217593  215 P 215
Cdd:PLN03150 507 P 507
LRR_8 pfam13855
Leucine rich repeat;
249-305 2.28e-08

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 50.60  E-value: 2.28e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 15217593   249 LNYLDLSQNNLSGTIPTFLSNFKVLDSLDLSRNRFSGVVPKSLANMPKLFHLNLSHN 305
Cdd:pfam13855   3 LRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGN 59
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
92-279 2.40e-08

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 56.10  E-value: 2.40e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217593  92 TISPSLAKLQHLVGIYFTNlrNITGSFPQFLFQLPNVKQVYFTNSRLSgPLPANIGALSELGELSLDGNLFTgPIPSsIS 171
Cdd:COG4886 173 DLPEELGNLTNLKELDLSN--NQITDLPEPLGNLTNLEELDLSGNQLT-DLPEPLANLTNLETLDLSNNQLT-DLPE-LG 247

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217593 172 NLTRLYLLNLGDNLLTgTIPlGLANLKILLSLNFGNNRLSETIPDIFKSMQKLQSLTLSRNKFSGNLPPSIASLKPILNY 251
Cdd:COG4886 248 NLTNLEELDLSNNQLT-DLP-PLANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLL 325

                       170       180
                ....*....|....*....|....*...
gi 15217593 252 LDLSQNNLSGTIPTFLSNFKVLDSLDLS 279
Cdd:COG4886 326 LLLLLKGLLVTLTTLALSLSLLALLTLL 353
LRR_RI cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ...
 149-330 1.71e-06

Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).


Pssm-ID: 238064 [Multi-domain]  Cd Length: 319  Bit Score: 49.66  E-value: 1.71e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217593 149 LSELGELSLDGNLFTGP----IPSSISNLTRLYLLNLGDNLlTGTIPLGLANLkillslnfgnnrlsetiPDIFKSMQKL 224
Cdd:cd00116  22 LLCLQVLRLEGNTLGEEaakaLASALRPQPSLKELCLSLNE-TGRIPRGLQSL-----------------LQGLTKGCGL 83

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217593 225 QSLTLSRNKFSGNLPPSIASL--KPILNYLDLSQNNLSGTIPTFL-----SNFKVLDSLDLSRNRFSGVVPKSLAN---- 293
Cdd:cd00116  84 QELDLSDNALGPDGCGVLESLlrSSSLQELKLNNNGLGDRGLRLLakglkDLPPALEKLVLGRNRLEGASCEALAKalra 163

                       170       180       190       200
                ....*....|....*....|....*....|....*....|..
gi 15217593 294 MPKLFHLNLSHNFLTGP-----LPAMKNVDGLATLDLSYNQF 330
Cdd:cd00116 164 NRDLKELNLANNGIGDAgiralAEGLKANCNLEVLDLNNNGL 205
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 83-210 2.30e-06

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 50.23  E-value: 2.30e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217593   83 DVTGSFLSGTISPSLAKLQHLVGIYFTNlRNITGSFPQFLFQLPNVKQVYFTNSRLSGPLPANIGALSELGELSLDGNLF 162
Cdd:PLN00113 481 DLSRNQFSGAVPRKLGSLSELMQLKLSE-NKLSGEIPDELSSCKKLVSLDLSHNQLSGQIPASFSEMPVLSQLDLSQNQL 559

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 15217593  163 TGPIPSSISNLTRLYLLNLGDNLLTGTIPLGLANLKILLSLNFGNNRL 210
Cdd:PLN00113 560 SGEIPKNLGNVESLVQVNISHNHLHGSLPSTGAFLAINASAVAGNIDL 607
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 252-454 2.38e-06

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 50.23  E-value: 2.38e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217593  252 LDLSQNNLSGTIPTFLSNFKVLDSLDLSRNRFSGVVPKSLANMP-KLFHLNLSHNFLTGPLPAmknvdglatldlsynqf 330
Cdd:PLN00113  74 IDLSGKNISGKISSAIFRLPYIQTINLSNNQLSGPIPDDIFTTSsSLRYLNLSNNNFTGSIPR----------------- 136

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217593  331 hlktipkwvTSSPSMYSLklvkcginmsldnwkpvrpniyfyiDLSENEISGsltwffnlahnlyefqasgnKLRFDMGK 410
Cdd:PLN00113 137 ---------GSIPNLETL-------------------------DLSNNMLSG--------------------EIPNDIGS 162

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 15217593  411 LNlseRLESLDLSRNLIFGKVPMTVAKLQKL---NLSHNHLCGKLPV 454
Cdd:PLN00113 163 FS---SLKVLDLGGNVLVGKIPNSLTNLTSLeflTLASNQLVGQIPR 206
PLN03150 PLN03150
hypothetical protein; Provisional
 272-330 1.48e-05

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 47.50  E-value: 1.48e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217593  272 VLDSLDLSRNRFSGVVPKSLANMPKLFHLNLSHNFLTGPLPA-MKNVDGLATLDLSYNQF 330
Cdd:PLN03150 419 FIDGLGLDNQGLRGFIPNDISKLRHLQSINLSGNSIRGNIPPsLGSITSLEVLDLSYNSF 478
PLN03210 PLN03210
Resistant to P. syringae 6; Provisional
 108-385 2.36e-05

Resistant to P. syringae 6; Provisional


Pssm-ID: 215633 [Multi-domain]  Cd Length: 1153  Bit Score: 47.18  E-value: 2.36e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217593   108 FTNLRNITGSFPQFLFQLP------NVKQVYFTNSRLSGPLPANIGALSELGELSLDGNLFTGPIPSSIsNLTRLYLLNL 181
Cdd:PLN03210  633 LTGLRNIDLRGSKNLKEIPdlsmatNLETLKLSDCSSLVELPSSIQYLNKLEDLDMSRCENLEILPTGI-NLKSLYRLNL 711

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217593   182 GdnlltgtiplGLANLKILL--SLNFGNNRLSETIPDIFKS---MQKLQSLTLSRNKFSGN------LPPSIASLKPILN 250
Cdd:PLN03210  712 S----------GCSRLKSFPdiSTNISWLDLDETAIEEFPSnlrLENLDELILCEMKSEKLwervqpLTPLMTMLSPSLT 781

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217593   251 YLDLSQNNLSGTIPTFLSNFKVLDSLDLSRNRFSGVVPKSLaNMPKLFHLNLSHNFLTGPLPAMKNvdGLATLDLSYNQf 330
Cdd:PLN03210  782 RLFLSDIPSLVELPSSIQNLHKLEHLEIENCINLETLPTGI-NLESLESLDLSGCSRLRTFPDIST--NISDLNLSRTG- 857

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 15217593   331 hLKTIPKWVTSSPSMYSLKLVKCginmslDNWKPVRPNIYFYIDLSENEIS--GSLT 385
Cdd:PLN03210  858 -IEEVPWWIEKFSNLSFLDMNGC------NNLQRVSLNISKLKHLETVDFSdcGALT 907
LRR_8 pfam13855
Leucine rich repeat;
273-330 2.55e-05

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 41.74  E-value: 2.55e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 15217593   273 LDSLDLSRNRFSGVVPKSLANMPKLFHLNLSHNFLTGPLP-AMKNVDGLATLDLSYNQF 330
Cdd:pfam13855   3 LRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPgAFSGLPSLRYLDLSGNRL 61
LRR_8 pfam13855
Leucine rich repeat;
174-234 4.22e-05

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 41.36  E-value: 4.22e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 15217593   174 TRLYLLNLGDNLLTGTIPLGLANLKILLSLNFGNNRLSETIPDIFKSMQKLQSLTLSRNKF 234
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
201-448 8.82e-05

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 44.92  E-value: 8.82e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217593 201 LSLNFGNNRLSETIPDIFKSMQKLQSLTLSRNKFSGNLPPSIASLKPILNYLDLSQNNLSGTIPTFLSNFKVLDSLDLSR 280
Cdd:COG4886   1 LLLLLLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLL 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217593 281 NRFSG-VVPKSLANMPKLFHLNLSHNFLTGPLPAmknvdgLATLDLSYNQfhLKTIPKWVTSSPSMYSLKLVKCGINmSL 359
Cdd:COG4886  81 LLSLLlLGLTDLGDLTNLTELDLSGNEELSNLTN------LESLDLSGNQ--LTDLPEELANLTNLKELDLSNNQLT-DL 151

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217593 360 DNWKPVRPNIYfYIDLSENEISGSLTWFFNLaHNLYEFQASGNKLR---FDMGKLnlsERLESLDLSRNLIfGKVPMTVA 436
Cdd:COG4886 152 PEPLGNLTNLK-SLDLSNNQLTDLPEELGNL-TNLKELDLSNNQITdlpEPLGNL---TNLEELDLSGNQL-TDLPEPLA 225

                       250
                ....*....|....*
gi 15217593 437 ---KLQKLNLSHNHL 448
Cdd:COG4886 226 nltNLETLDLSNNQL 240
LRR_8 pfam13855
Leucine rich repeat;
202-259 1.88e-04

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 39.43  E-value: 1.88e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 15217593   202 SLNFGNNRLSETIPDIFKSMQKLQSLTLSRNKFSGNLPPSIASLkPILNYLDLSQNNL 259
Cdd:pfam13855   5 SLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGL-PSLRYLDLSGNRL 61
RNA1 COG5238
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ...
 173-329 2.35e-04

Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444072 [Multi-domain]  Cd Length: 434  Bit Score: 43.63  E-value: 2.35e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217593 173 LTRLYLLNLGDNLLT--GTIPLG--LANLKILLSLNFGNNRLSET----IPDIFKSMQKLQSLTLSRNKFSG----NLPP 240
Cdd:COG5238 235 NKSLTTLDLSNNQIGdeGVIALAeaLKNNTTVETLYLSGNQIGAEgaiaLAKALQGNTTLTSLDLSVNRIGDegaiALAE 314

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217593 241 SIASLKPiLNYLDLSQNNLS--GTIPTF--LSNFKVLDSLDLSRNRFSG----VVPKSLANMPKLFHLNLSHNFLTG--- 309
Cdd:COG5238 315 GLQGNKT-LHTLNLAYNGIGaqGAIALAkaLQENTTLHSLDLSDNQIGDegaiALAKYLEGNTTLRELNLGKNNIGKqga 393

                       170       180
                ....*....|....*....|.
gi 15217593 310 -PLPAMKNVDGLATLDLSYNQ 329
Cdd:COG5238 394 eALIDALQTNRLHTLILDGNL 414
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
92-278 5.25e-04

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 42.23  E-value: 5.25e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217593  92 TISPSLAKLQHLVGIYFTNlrNITGSFPQFLFQLPNVKQVYFTNSRLSgPLPaNIGALSELGELSLDGNLFTGpIPSSiS 171
Cdd:COG4886 196 DLPEPLGNLTNLEELDLSG--NQLTDLPEPLANLTNLETLDLSNNQLT-DLP-ELGNLTNLEELDLSNNQLTD-LPPL-A 269

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217593 172 NLTRLYLLNLGDNLLTGTIPLGLANLKILLSLNFGNNRLSETIPDIFKSMQKLQSLTLSRNKFSGNLPPSIASLKPILNY 251
Cdd:COG4886 270 NLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLAL 349

                       170       180
                ....*....|....*....|....*..
gi 15217593 252 LDLSQNNLSGTIPTFLSNFKVLDSLDL 278
Cdd:COG4886 350 LTLLLLLNLLSLLLTLLLTLGLLGLLE 376
PLN03150 PLN03150
hypothetical protein; Provisional
 392-476 5.45e-04

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 42.50  E-value: 5.45e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217593  392 HNLYEFQASGNKLRfdmGKLNLS----ERLESLDLSRNLIFGKVPMTVAK---LQKLNLSHNHLCGKLPV---------T 455
Cdd:PLN03150 442 RHLQSINLSGNSIR---GNIPPSlgsiTSLEVLDLSYNSFNGSIPESLGQltsLRILNLNGNSLSGRVPAalggrllhrA 518

                         90       100
                 ....*....|....*....|..
gi 15217593  456 KFpasAFVGNDCLCGSP-LSPC 476
Cdd:PLN03150 519 SF---NFTDNAGLCGIPgLRAC 537
PLN03210 PLN03210
Resistant to P. syringae 6; Provisional
 166-388 9.72e-04

Resistant to P. syringae 6; Provisional


Pssm-ID: 215633 [Multi-domain]  Cd Length: 1153  Bit Score: 41.78  E-value: 9.72e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217593   166 IPSSISNLTRLYLLNLGDNLLTGTIPLGLaNLKILLSLNF-GNNRLsETIPDIfksMQKLQSLTLSRNKFSgNLPPSIAS 244
Cdd:PLN03210  794 LPSSIQNLHKLEHLEIENCINLETLPTGI-NLESLESLDLsGCSRL-RTFPDI---STNISDLNLSRTGIE-EVPWWIEK 867

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217593   245 LKpILNYLDLSQ-NNLSGTIPTfLSNFKVLDSLDLSR---------NRFSGVVPKSLAN----MPKLFHLNLSHNFLTGP 310
Cdd:PLN03210  868 FS-NLSFLDMNGcNNLQRVSLN-ISKLKHLETVDFSDcgalteaswNGSPSEVAMATDNihskLPSTVCINFINCFNLDQ 945

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 15217593   311 LPAMKNVDGLATLDLSYNQfhlktIPKWVTSSPSMYSLklvkcgINMSLDNWKPVRPNIYFYIDLSENEISGSLTWFF 388
Cdd:PLN03210  946 EALLQQQSIFKQLILSGEE-----VPSYFTHRTTGASL------TNIPLLHISPCQPFFRFRACAVVDSESFFIISVS 1012
LRR_RI cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ...
 85-284 2.06e-03

Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).


Pssm-ID: 238064 [Multi-domain]  Cd Length: 319  Bit Score: 40.03  E-value: 2.06e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217593  85 TGSFLSGTIS-----PSLAKLQHLVgiYFTNLRNITGSFP-QFLFQLPNVKQVYFTNSRLS-GPLPANIGALSE----LG 153
Cdd:cd00116  63 TGRIPRGLQSllqglTKGCGLQELD--LSDNALGPDGCGVlESLLRSSSLQELKLNNNGLGdRGLRLLAKGLKDlppaLE 140

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15217593 154 ELSLDGNLFTG----PIPSSISNLTRLYLLNLGDNLLTG----TIPLGLANLKILLSLNFGNNRLSET----IPDIFKSM 221
Cdd:cd00116 141 KLVLGRNRLEGasceALAKALRANRDLKELNLANNGIGDagirALAEGLKANCNLEVLDLNNNGLTDEgasaLAETLASL 220

                       170       180       190       200       210       220       230
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 15217593 222 QKLQSLTLSRNKFSG----NLPPSIASLKPILNYLDLSQNNL----SGTIPTFLSNFKVLDSLDLSRNRFS 284
Cdd:cd00116 221 KSLEVLNLGDNNLTDagaaALASALLSPNISLLTLSLSCNDItddgAKDLAEVLAEKESLLELDLRGNKFG 291
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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