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Conserved domains on  [gi|240254144|ref|NP_173840|]
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GYF domain-containing protein [Arabidopsis thaliana]

Protein Classification

GYF domain-containing protein( domain architecture ID 10648319)

GYF (glycine-tyrosine-phenylalanine) domain-containing protein binds proline-rich sequences and is involved in protein-protein interactions

CATH:  3.30.1490.40
Gene Ontology:  GO:0005515|GO:0070064
PubMed:  10404223|16403013
SCOP:  4001496

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
GYF smart00444
Contains conserved Gly-Tyr-Phe residues; Proline-binding domain in CD2-binding protein. ...
 477-532 3.94e-18

Contains conserved Gly-Tyr-Phe residues; Proline-binding domain in CD2-binding protein. Contains conserved Gly-Tyr-Phe residues.


:

Pssm-ID: 214666  Cd Length: 56  Bit Score: 79.30  E-value: 3.94e-18
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....*.
gi 240254144    477 FLFLYIDPQGVIQGPFIGSDIISWFEQGFFGTDLQVRLANAPEGTPFQDLGRVMSY 532
Cdd:smart00444    1 VLWLYKDPDGEIQGPFTASQMSQWYQAGYFPDSLQIKRLNEPPYETLGDLDRLLGL 56
 
Name Accession Description Interval E-value
GYF smart00444
Contains conserved Gly-Tyr-Phe residues; Proline-binding domain in CD2-binding protein. ...
 477-532 3.94e-18

Contains conserved Gly-Tyr-Phe residues; Proline-binding domain in CD2-binding protein. Contains conserved Gly-Tyr-Phe residues.


Pssm-ID: 214666  Cd Length: 56  Bit Score: 79.30  E-value: 3.94e-18
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....*.
gi 240254144    477 FLFLYIDPQGVIQGPFIGSDIISWFEQGFFGTDLQVRLANAPEGTPFQDLGRVMSY 532
Cdd:smart00444    1 VLWLYKDPDGEIQGPFTASQMSQWYQAGYFPDSLQIKRLNEPPYETLGDLDRLLGL 56
GYF cd00072
GYF domain: contains conserved Gly-Tyr-Phe residues; Proline-binding domain in CD2-binding and ...
 476-534 1.45e-17

GYF domain: contains conserved Gly-Tyr-Phe residues; Proline-binding domain in CD2-binding and other proteins. Involved in signaling lymphocyte activity. Also present in other unrelated proteins (mainly unknown) derived from diverse eukaryotic species.


Pssm-ID: 238027  Cd Length: 57  Bit Score: 77.73  E-value: 1.45e-17
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 240254144  476 DFLFLYIDPQGVIQGPFIGSDIISWFEQGFFGTDLQVRLANapEGTPFQDLGRVMSYLK 534
Cdd:cd00072     1 EVQWFYKDPQGEIQGPFSASQMLQWYQAGYFPDGLQVRRLD--NGGEFYTLGDILFDLG 57
GYF pfam02213
GYF domain; The GYF domain is named because of the presence of Gly-Tyr-Phe residues. The GYF ...
 479-526 1.27e-10

GYF domain; The GYF domain is named because of the presence of Gly-Tyr-Phe residues. The GYF domain is a proline-binding domain in CD2-binding protein Swiss:O95400.


Pssm-ID: 460496  Cd Length: 45  Bit Score: 57.59  E-value: 1.27e-10
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*...
gi 240254144   479 FLYIDPQGVIQGPFIGSDIISWFEQGFFGTDLQVRLAnapEGTPFQDL 526
Cdd:pfam02213    1 WEYKDPQGEVQGPFSSAEMQEWYKAGYFPDDLPVRRV---GDTEFYPL 45
 
Name Accession Description Interval E-value
GYF smart00444
Contains conserved Gly-Tyr-Phe residues; Proline-binding domain in CD2-binding protein. ...
 477-532 3.94e-18

Contains conserved Gly-Tyr-Phe residues; Proline-binding domain in CD2-binding protein. Contains conserved Gly-Tyr-Phe residues.


Pssm-ID: 214666  Cd Length: 56  Bit Score: 79.30  E-value: 3.94e-18
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....*.
gi 240254144    477 FLFLYIDPQGVIQGPFIGSDIISWFEQGFFGTDLQVRLANAPEGTPFQDLGRVMSY 532
Cdd:smart00444    1 VLWLYKDPDGEIQGPFTASQMSQWYQAGYFPDSLQIKRLNEPPYETLGDLDRLLGL 56
GYF cd00072
GYF domain: contains conserved Gly-Tyr-Phe residues; Proline-binding domain in CD2-binding and ...
 476-534 1.45e-17

GYF domain: contains conserved Gly-Tyr-Phe residues; Proline-binding domain in CD2-binding and other proteins. Involved in signaling lymphocyte activity. Also present in other unrelated proteins (mainly unknown) derived from diverse eukaryotic species.


Pssm-ID: 238027  Cd Length: 57  Bit Score: 77.73  E-value: 1.45e-17
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 240254144  476 DFLFLYIDPQGVIQGPFIGSDIISWFEQGFFGTDLQVRLANapEGTPFQDLGRVMSYLK 534
Cdd:cd00072     1 EVQWFYKDPQGEIQGPFSASQMLQWYQAGYFPDGLQVRRLD--NGGEFYTLGDILFDLG 57
GYF pfam02213
GYF domain; The GYF domain is named because of the presence of Gly-Tyr-Phe residues. The GYF ...
 479-526 1.27e-10

GYF domain; The GYF domain is named because of the presence of Gly-Tyr-Phe residues. The GYF domain is a proline-binding domain in CD2-binding protein Swiss:O95400.


Pssm-ID: 460496  Cd Length: 45  Bit Score: 57.59  E-value: 1.27e-10
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*...
gi 240254144   479 FLYIDPQGVIQGPFIGSDIISWFEQGFFGTDLQVRLAnapEGTPFQDL 526
Cdd:pfam02213    1 WEYKDPQGEVQGPFSSAEMQEWYKAGYFPDDLPVRRV---GDTEFYPL 45
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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