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Conserved domains on  [gi|15220846|ref|NP_173222|]
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early nodulin-like protein 22 [Arabidopsis thaliana]

Protein Classification

cupredoxin domain-containing protein; multicopper oxidase( domain architecture ID 10181137)

cupredoxin domain-containing protein may contain a type I copper center and be involved in inter-molecular electron transfer reactions| multicopper oxidase (MCO) that couples the oxidation of a substrate with a four-electron reduction of molecular oxygen to water, and which may contain three cupredoxin domains that include one mononuclear and one trinuclear copper center; similar to Pleurotus ostreatus laccase-2 that may be involved in lignin degradation and detoxification of lignin-derived products

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Plantacyanin cd11013
Plantacyanin is a subclass of phytocyanins, plant type I copper proteins; Plantacyanins belong ...
 39-136 8.24e-48

Plantacyanin is a subclass of phytocyanins, plant type I copper proteins; Plantacyanins belong to the phytocyanin family of blue copper proteins, a ubiquitous family of plant cupredoxins. Plantacyanin is involved in electron transfer reactions with the Cu center transitioning between the oxidized Cu(II) form and the reduced Cu(I) form. The exact function of plantacyanin is unknown. However plantacyanin is shown to play a role in reproduction in Arabidopsis. Plantacyanins may also be stress-related proteins and be involved in plant defense responses.


:

Pssm-ID: 259899  Cd Length: 95  Bit Score: 149.04  E-value: 8.24e-48
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220846  39 TTYIVGGDDGWDPVVPmdTWARGKTFYAGDILEFKYDYQRFNLIVVNRTGYETCEANVGAIEYSSGDDKIQLNYGYNYFI 118
Cdd:cd11013   1 ATYVVGDSIGWTFGVV--GWPNGKTFRAGDVLVFNYDPSAHNVVVVDEGGYRTCKAPPGAIVYTSGDDKITLPKGVNYFI 78

                        90
                ....*....|....*...
gi 15220846 119 GTYtPEDCTTGLKMAIKA 136
Cdd:cd11013  79 CSF-PGHCTSGMKIAVTA 95
 
Name Accession Description Interval E-value
Plantacyanin cd11013
Plantacyanin is a subclass of phytocyanins, plant type I copper proteins; Plantacyanins belong ...
 39-136 8.24e-48

Plantacyanin is a subclass of phytocyanins, plant type I copper proteins; Plantacyanins belong to the phytocyanin family of blue copper proteins, a ubiquitous family of plant cupredoxins. Plantacyanin is involved in electron transfer reactions with the Cu center transitioning between the oxidized Cu(II) form and the reduced Cu(I) form. The exact function of plantacyanin is unknown. However plantacyanin is shown to play a role in reproduction in Arabidopsis. Plantacyanins may also be stress-related proteins and be involved in plant defense responses.


Pssm-ID: 259899  Cd Length: 95  Bit Score: 149.04  E-value: 8.24e-48
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220846  39 TTYIVGGDDGWDPVVPmdTWARGKTFYAGDILEFKYDYQRFNLIVVNRTGYETCEANVGAIEYSSGDDKIQLNYGYNYFI 118
Cdd:cd11013   1 ATYVVGDSIGWTFGVV--GWPNGKTFRAGDVLVFNYDPSAHNVVVVDEGGYRTCKAPPGAIVYTSGDDKITLPKGVNYFI 78

                        90
                ....*....|....*...
gi 15220846 119 GTYtPEDCTTGLKMAIKA 136
Cdd:cd11013  79 CSF-PGHCTSGMKIAVTA 95
Cu_bind_like pfam02298
Plastocyanin-like domain; This family represents a domain found in flowering plants related to ...
 57-130 1.14e-19

Plastocyanin-like domain; This family represents a domain found in flowering plants related to the copper binding protein plastocyanin. Some members of this family may not bind copper due to the lack of key residues.


Pssm-ID: 280462  Cd Length: 84  Bit Score: 77.39  E-value: 1.14e-19
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 15220846    57 TWARGKTFYAGDILEFKYDYQRFNLIVVNRTGYETCEANVGAIEYSSGDDKIQLN-YGYNYFIGTYtPEDCTTGL 130
Cdd:pfam02298  11 TWAQGKTFRVGDTLVFKYDSDFHNVVEVTKADYESCDTSKPIRNYTTGSDKVTLTkPGPNYFICGV-PGHCKFGM 84
PLN03148 PLN03148
Blue copper-like protein; Provisional
 24-134 8.26e-18

Blue copper-like protein; Provisional


Pssm-ID: 178693  Cd Length: 167  Bit Score: 74.91  E-value: 8.26e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220846   24 LCLFLANAVTyARRPTTYIVGGDDGWDPVVPMDTWARGKTFYAGDILEFKYDYQRFNLIVVNRTGYETCEANVGAIEYSS 103
Cdd:PLN03148   7 FCFFALFSAS-ATTATDHIVGANKGWNPGINYTLWANNQTFYVGDLISFRYQKTQYNVFEVNQTGYDNCTTEGAAGNWTS 85

                         90       100       110
                 ....*....|....*....|....*....|..
gi 15220846  104 GDDKIQLNYGYN-YFIGTYTpeDCTTGLKMAI 134
Cdd:PLN03148  86 GKDFIPLNKAKRyYFICGNG--QCFNGMKVTI 115
 
Name Accession Description Interval E-value
Plantacyanin cd11013
Plantacyanin is a subclass of phytocyanins, plant type I copper proteins; Plantacyanins belong ...
 39-136 8.24e-48

Plantacyanin is a subclass of phytocyanins, plant type I copper proteins; Plantacyanins belong to the phytocyanin family of blue copper proteins, a ubiquitous family of plant cupredoxins. Plantacyanin is involved in electron transfer reactions with the Cu center transitioning between the oxidized Cu(II) form and the reduced Cu(I) form. The exact function of plantacyanin is unknown. However plantacyanin is shown to play a role in reproduction in Arabidopsis. Plantacyanins may also be stress-related proteins and be involved in plant defense responses.


Pssm-ID: 259899  Cd Length: 95  Bit Score: 149.04  E-value: 8.24e-48
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220846  39 TTYIVGGDDGWDPVVPmdTWARGKTFYAGDILEFKYDYQRFNLIVVNRTGYETCEANVGAIEYSSGDDKIQLNYGYNYFI 118
Cdd:cd11013   1 ATYVVGDSIGWTFGVV--GWPNGKTFRAGDVLVFNYDPSAHNVVVVDEGGYRTCKAPPGAIVYTSGDDKITLPKGVNYFI 78

                        90
                ....*....|....*...
gi 15220846 119 GTYtPEDCTTGLKMAIKA 136
Cdd:cd11013  79 CSF-PGHCTSGMKIAVTA 95
Phytocyanin cd04216
Phytocyanins are plant blue or type I copper proteins; Phytocyanins are plant blue or type I ...
 39-136 1.81e-27

Phytocyanins are plant blue or type I copper proteins; Phytocyanins are plant blue or type I copper proteins. They are involved in electron transfer reactions with the Cu center transitioning between the oxidized Cu(II) form and the reduced Cu(I) form. Phytocyanins are classified into four groups: stellacyanin, plantacyanin, uclacyanin and early nodulin groups. Stellacyanin appears to be associated with the plant cell wall; it may be involved in oxidative reactions to build polymeric material making up the cell wall. Plantacyanin is shown to play a role in reproduction in Arabidopsis. Plantacyanins may also be stress-related proteins and may be involved in plant defense responses. The early nodulin-like protein (OsENODL1) from Oryza sativa is expressed specifically at the late developmental stage of the seeds.


Pssm-ID: 259878 [Multi-domain]  Cd Length: 98  Bit Score: 97.72  E-value: 1.81e-27
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220846  39 TTYIVGGDDGWDPVVPMDTWARGKTFYAGDILEFKYDYQRFNLIVVNRTGYETCEANVGAIEYSSGDDKIQLN-YGYNYF 117
Cdd:cd04216   1 TDYTVGDSNGWDLPVNYTAWASGKTFRVGDSLVFNYNAGAHSVVEVNEADYDSCDTSNPINTYTSGNDSVTLTkPGTRYF 80

                        90
                ....*....|....*....
gi 15220846 118 IGTyTPEDCTTGLKMAIKA 136
Cdd:cd04216  81 ICG-VPGHCQSGMKLAINV 98
Cu_bind_like pfam02298
Plastocyanin-like domain; This family represents a domain found in flowering plants related to ...
 57-130 1.14e-19

Plastocyanin-like domain; This family represents a domain found in flowering plants related to the copper binding protein plastocyanin. Some members of this family may not bind copper due to the lack of key residues.


Pssm-ID: 280462  Cd Length: 84  Bit Score: 77.39  E-value: 1.14e-19
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 15220846    57 TWARGKTFYAGDILEFKYDYQRFNLIVVNRTGYETCEANVGAIEYSSGDDKIQLN-YGYNYFIGTYtPEDCTTGL 130
Cdd:pfam02298  11 TWAQGKTFRVGDTLVFKYDSDFHNVVEVTKADYESCDTSKPIRNYTTGSDKVTLTkPGPNYFICGV-PGHCKFGM 84
PLN03148 PLN03148
Blue copper-like protein; Provisional
 24-134 8.26e-18

Blue copper-like protein; Provisional


Pssm-ID: 178693  Cd Length: 167  Bit Score: 74.91  E-value: 8.26e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220846   24 LCLFLANAVTyARRPTTYIVGGDDGWDPVVPMDTWARGKTFYAGDILEFKYDYQRFNLIVVNRTGYETCEANVGAIEYSS 103
Cdd:PLN03148   7 FCFFALFSAS-ATTATDHIVGANKGWNPGINYTLWANNQTFYVGDLISFRYQKTQYNVFEVNQTGYDNCTTEGAAGNWTS 85

                         90       100       110
                 ....*....|....*....|....*....|..
gi 15220846  104 GDDKIQLNYGYN-YFIGTYTpeDCTTGLKMAI 134
Cdd:PLN03148  86 GKDFIPLNKAKRyYFICGNG--QCFNGMKVTI 115
Phytocyanin_like_1 cd11017
A subclass of phytocyanins, plant blue or type I copper proteins; Phytocyanins are plant blue ...
 39-136 6.15e-16

A subclass of phytocyanins, plant blue or type I copper proteins; Phytocyanins are plant blue or type I copper proteins. They are involved in electron transfer reactions with the Cu center transitioning between the oxidized Cu(II) form and the reduced Cu(I) form. Phytocyanins are classified into four groups: stellacyanin, plantacyanin, uclacyanin and early nodulin groups. Members of this unknown subgroup appear to have lost the T1 copper binding site.


Pssm-ID: 259903  Cd Length: 99  Bit Score: 68.19  E-value: 6.15e-16
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220846  39 TTYIVGGDD-GWDPVVPMDTWARGKTFYAGDILEFKYDYQRFNLIVVNRTGYETCEANvGAIEY--SSGDDKIQLNY-GY 114
Cdd:cd11017   1 TLHTVGGNRiGWNPNINYTDWAKMHGFYSGDWLVFRYQRGRHNVVQVNETGYDNCDAS-NPISNysSGGRDIFQLNEtKR 79

                        90       100
                ....*....|....*....|..
gi 15220846 115 NYFIGTYTpeDCTTGLKMAIKA 136
Cdd:cd11017  80 YYFICGRG--YCYGGMKLAITV 99
OsENODL1_like cd11019
Early nodulin-like protein (OsENODL1) and similar proteins; This family includes early ...
 39-134 9.38e-16

Early nodulin-like protein (OsENODL1) and similar proteins; This family includes early nodulin-like protein (OsENODL1) from Oryza sativa and similar proteins. It belongs to the phytocyanin family of blue copper proteins, a ubiquitous family of plant cupredoxins. Phytocyanin is involved in electron transfer reactions with the Cu center transitioning between the oxidized Cu(II) form and the reduced Cu(I) form. OsENODL1 expression occurs specifically at the late developmental stage of the seeds. Members of this subgroup appear to have lost the T1 copper binding site.


Pssm-ID: 259905  Cd Length: 103  Bit Score: 67.68  E-value: 9.38e-16
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220846  39 TTYIVGGDDGWdpVVPMDT------WARGKTFYAGDILEFKYDYQRFNLIVVNRTGYETCEANVGAIEYSSGDDKIQLN- 111
Cdd:cd11019   1 REFKVGGKDGW--KVPPSAsesynqWAERNRFQVGDSLVFKYDKGNDSVLEVTKEDYDSCNTSSPIARFNDGNTKFTLDr 78

                        90       100
                ....*....|....*....|...
gi 15220846 112 YGYNYFIGTyTPEDCTTGLKMAI 134
Cdd:cd11019  79 SGPFYFISG-APGHCEKGQKLIV 100
Mavicyanin cd11014
Mavicyanin is a subclass of phytocyanins, a plant blue copper protein; Mavicyanin is a ...
 39-135 2.59e-14

Mavicyanin is a subclass of phytocyanins, a plant blue copper protein; Mavicyanin is a glycosylated protein isolated from Cucurbita pepo medullosa (zucchini) peelings. It belongs to the phytocyanin family of blue copper proteins, a ubiquitous family of plant cupredoxins. Mavicyanin is involved in electron transfer reactions with the Cu center transitioning between the oxidized Cu(II) form and the reduced Cu(I) form. The copper is tetrahedrally coordinated by a cysteine, 2 histidines, and a glutamine residue, like in the case of stellacyanin. The biological roles of mavicyanin have not been elucidated yet.


Pssm-ID: 259900  Cd Length: 101  Bit Score: 63.95  E-value: 2.59e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220846  39 TTYIVGGDDGWDPVVPMD--TWARGKTFYAGDILEFKYDYQRFNLIVVNRTGYETCEANVGAIEYSSGDDKIQLNY-GYN 115
Cdd:cd11014   1 TVYKVGDSDGWTVYDSDYyyKWSSSKTFHVGDSLIFQYNKEFHDVTEVTGEEFESCNSTSPIAVYNTGHDIIKLTKpGQY 80

                        90       100
                ....*....|....*....|
gi 15220846 116 YFIgTYTPEDCTTGLKMAIK 135
Cdd:cd11014  81 YFI-CGVPGHCDSGQKLQVN 99
Stellacyanin cd13920
Stellacyanin is a subclass of phytocyanins, a plant type I copper protein; Stellacyanin is a ...
 39-135 5.36e-13

Stellacyanin is a subclass of phytocyanins, a plant type I copper protein; Stellacyanin is a subclass of the phytocyanins, a ubiquitous family of plant cupredoxins. Stellacyanin is involved in electron transfer reactions with the Cu center transitioning between the oxidized Cu(II) form and the reduced Cu(I) form. The copper is tetrahedrally coordinated by a cysteine, 2 histidines, and a glutamine residue. The glutamine residue substitutes for a methione ligand typically found in other blue copper proteins. The exact function of stellacyanin is unknown. However, stellacyanin appears to be associated with the plant cell wall; it may be involved in oxidative reactions to build polymeric material making up the cell wall.


Pssm-ID: 259987 [Multi-domain]  Cd Length: 101  Bit Score: 60.79  E-value: 5.36e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15220846  39 TTYIVGGDDGWdpVVPMD-----TWARGKTFYAGDILEFKYDYQRFNLIVVNRTGYETCEANVGAIEYSSGDDKIQLNY- 112
Cdd:cd13920   1 TDHIVGGSLGW--SIPPNasfytDWAANRTFRVGDSLVFNFEAGVHNVVEVSKEEYDNCTTTNPIKVFTTGPVIITLNEt 78

                        90       100
                ....*....|....*....|....*.
gi 15220846 113 GYNYFI---GTYtpedCTTGLKMAIK 135
Cdd:cd13920  79 GTRYFIctvGNH----CSLGQKVSIN 100
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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