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Conserved domains on  [gi|15222970|ref|NP_172839|]
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QUASIMODO2 LIKE 1 [Arabidopsis thaliana]

Protein Classification

class I SAM-dependent methyltransferase( domain architecture ID 708142)

class I SAM-dependent methyltransferase catalyzes the methylation of one or more specific substrates using S-adenosyl-L-methionine (SAM or AdoMet) as the methyl donor; similar to Arabidopsis thaliana methyltransferase PMTs

CATH:  2.20.25.110
EC:  2.1.1.-
Gene Ontology:  GO:0032259|GO:0008757|GO:0008168|GO:1904047
PubMed:  12504684|12826405
SCOP:  3000118

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Methyltransf_29 super family cl28725
Putative S-adenosyl-L-methionine-dependent methyltransferase; This family is a putative ...
 90-598 8.02e-156

Putative S-adenosyl-L-methionine-dependent methyltransferase; This family is a putative S-adenosyl-L-methionine (SAM)-dependent methyltransferase.


The actual alignment was detected with superfamily member pfam03141:

Pssm-ID: 335237 [Multi-domain]  Cd Length: 506  Bit Score: 456.77  E-value: 8.02e-156
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15222970    90 NYVPCYNVTES-------------DRNCEFAREEERCLVRPPRDYKIPLRWPVGRDIIWTGNVKITKdqfLSSGTMTKRL 156
Cdd:pfam03141   1 DYIPCLDNKRAikfllsrermehrERHCPPPEEKLNCLVPPPDGYKTPIPWPKSRDKVWYANVPHTK---LAEEKGGQNW 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15222970   157 MLLEENQITFhSDDGLIF-DGVKDYAFQIAEMIglgSDTEFpQAGIRTVLDIGCGFGSFGAHLVSLNVMPICIAEYETSG 235
Cdd:pfam03141  78 VKVEGDKFTF-PGGGTQFpHGADQYIDFIAQMI---PDIAW-GGRVRTALDVGCGVASFGAYLLSRDVLTMSFAPKDVHE 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15222970   236 SQVQLALERGLPAMIGNFFSKQLPYPALSFDMVHCAQCGITWDIKDAMLLLEVDRVLKPGGYFVLTSPTSKAQgnsPDTK 315
Cdd:pfam03141 153 AQVQFALERGIPAMLGVLGTKRLPYPSRSFDLAHCSRCRIPWTANDGILLLEVDRVLRPGGYFVLSGPPVYAR---TEED 229

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15222970   316 KTSISTRVDELSKKICWSLSGQQDETFLWQKTADPNCYSSRSQ-ASIPVCKDDD--SVPYYHPLVPCIS----------G 382
Cdd:pfam03141 230 LQEIWKEMEDLTKSLCWKLVAKKGDIAIWQKPLNNSCYNKREPgKKPPLCKDSDdpDAAWYVPMEACITplpevshevgG 309

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15222970   383 TKSKRWiPiqNRSRASGTSLSELEIHGIKPEEFDEDIQVWRSALKNYWSLLTPLIFSDHpkrpgdedpvppfymIRNAMD 462
Cdd:pfam03141 310 GWPEPW-P--ARLTAVPPRLSSGQIGGVSPESFKADTELWKKRVNKYKRLLKLGIDWGK---------------VRNVMD 371

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15222970   463 MNARYGNLNQALLNQGksVWVMNVVPVKARNTLPIILDRGFTGALHDWCEPFPTYPRTYDMLHANELLTHLsSERCSLMD 542
Cdd:pfam03141 372 MNAGFGGFAAALIDLP--VWVMNVVPVDSPNTLPVIYDRGLIGIYHDWCEAFSTYPRTYDLLHADHLFSLY-KKRCNLVD 448

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 15222970   543 LFLEMDRILRPEGWVVLSDKLGVIEMARTLAARVRWEARVIDIQDGS--DQRLLVCQK 598
Cdd:pfam03141 449 ILLEMDRILRPEGFVIIRDSVDVLDKVKKIAKAMRWEVRMTDTEDGPhvPEKILIAQK 506
 
Name Accession Description Interval E-value
Methyltransf_29 pfam03141
Putative S-adenosyl-L-methionine-dependent methyltransferase; This family is a putative ...
 90-598 8.02e-156

Putative S-adenosyl-L-methionine-dependent methyltransferase; This family is a putative S-adenosyl-L-methionine (SAM)-dependent methyltransferase.


Pssm-ID: 335237 [Multi-domain]  Cd Length: 506  Bit Score: 456.77  E-value: 8.02e-156
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15222970    90 NYVPCYNVTES-------------DRNCEFAREEERCLVRPPRDYKIPLRWPVGRDIIWTGNVKITKdqfLSSGTMTKRL 156
Cdd:pfam03141   1 DYIPCLDNKRAikfllsrermehrERHCPPPEEKLNCLVPPPDGYKTPIPWPKSRDKVWYANVPHTK---LAEEKGGQNW 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15222970   157 MLLEENQITFhSDDGLIF-DGVKDYAFQIAEMIglgSDTEFpQAGIRTVLDIGCGFGSFGAHLVSLNVMPICIAEYETSG 235
Cdd:pfam03141  78 VKVEGDKFTF-PGGGTQFpHGADQYIDFIAQMI---PDIAW-GGRVRTALDVGCGVASFGAYLLSRDVLTMSFAPKDVHE 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15222970   236 SQVQLALERGLPAMIGNFFSKQLPYPALSFDMVHCAQCGITWDIKDAMLLLEVDRVLKPGGYFVLTSPTSKAQgnsPDTK 315
Cdd:pfam03141 153 AQVQFALERGIPAMLGVLGTKRLPYPSRSFDLAHCSRCRIPWTANDGILLLEVDRVLRPGGYFVLSGPPVYAR---TEED 229

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15222970   316 KTSISTRVDELSKKICWSLSGQQDETFLWQKTADPNCYSSRSQ-ASIPVCKDDD--SVPYYHPLVPCIS----------G 382
Cdd:pfam03141 230 LQEIWKEMEDLTKSLCWKLVAKKGDIAIWQKPLNNSCYNKREPgKKPPLCKDSDdpDAAWYVPMEACITplpevshevgG 309

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15222970   383 TKSKRWiPiqNRSRASGTSLSELEIHGIKPEEFDEDIQVWRSALKNYWSLLTPLIFSDHpkrpgdedpvppfymIRNAMD 462
Cdd:pfam03141 310 GWPEPW-P--ARLTAVPPRLSSGQIGGVSPESFKADTELWKKRVNKYKRLLKLGIDWGK---------------VRNVMD 371

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15222970   463 MNARYGNLNQALLNQGksVWVMNVVPVKARNTLPIILDRGFTGALHDWCEPFPTYPRTYDMLHANELLTHLsSERCSLMD 542
Cdd:pfam03141 372 MNAGFGGFAAALIDLP--VWVMNVVPVDSPNTLPVIYDRGLIGIYHDWCEAFSTYPRTYDLLHADHLFSLY-KKRCNLVD 448

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 15222970   543 LFLEMDRILRPEGWVVLSDKLGVIEMARTLAARVRWEARVIDIQDGS--DQRLLVCQK 598
Cdd:pfam03141 449 ILLEMDRILRPEGFVIIRDSVDVLDKVKKIAKAMRWEVRMTDTEDGPhvPEKILIAQK 506
UbiE COG2226
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; ...
 202-301 2.37e-10

Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG is part of the Pathway/BioSystem: Biotin biosynthesis


Pssm-ID: 441828 [Multi-domain]  Cd Length: 143  Bit Score: 58.85  E-value: 2.37e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15222970 202 RTVLDIGCGFGSFGAHLVSLNVMPICIaeyETSGSQVQLALERGLPAMIGNFFSK----QLPYPALSFDMVHCAQCGITW 277
Cdd:COG2226  24 ARVLDLGCGTGRLALALAERGARVTGV---DISPEMLELARERAAEAGLNVEFVVgdaeDLPFPDGSFDLVISSFVLHHL 100

                        90       100
                ....*....|....*....|....
gi 15222970 278 DIKDAMLLlEVDRVLKPGGYFVLT 301
Cdd:COG2226 101 PDPERALA-EIARVLKPGGRLVVV 123
PLN02244 PLN02244
tocopherol O-methyltransferase
 197-331 8.03e-05

tocopherol O-methyltransferase


Pssm-ID: 215135 [Multi-domain]  Cd Length: 340  Bit Score: 45.12  E-value: 8.03e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15222970  197 PQAGIRTVLDIGCGFGSFGAHLV---SLNVMPICIAEYETSGSQvQLALERGLpamiGNFFSKQ------LPYPALSFDM 267
Cdd:PLN02244 115 DEKRPKRIVDVGCGIGGSSRYLArkyGANVKGITLSPVQAARAN-ALAAAQGL----SDKVSFQvadalnQPFEDGQFDL 189

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 15222970  268 VHCAQCGITWDIKdAMLLLEVDRVLKPGGYFVLTSPTSKaqgnspDTKKTSISTRVDELS--KKIC 331
Cdd:PLN02244 190 VWSMESGEHMPDK-RKFVQELARVAAPGGRIIIVTWCHR------DLEPGETSLKPDEQKllDKIC 248
AdoMet_MTases cd02440
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ...
 203-301 1.23e-04

S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).


Pssm-ID: 100107 [Multi-domain]  Cd Length: 107  Bit Score: 41.65  E-value: 1.23e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15222970 203 TVLDIGCGFGSFGAHLVSLNvmPICIAEYETSGSQVQLALERGLPAMIGNF------FSKQLPYPALSFDMVHCAQCGIT 276
Cdd:cd02440   1 RVLDLGCGTGALALALASGP--GARVTGVDISPVALELARKAAAALLADNVevlkgdAEELPPEADESFDVIISDPPLHH 78

                        90       100
                ....*....|....*....|....*
gi 15222970 277 WDIKDAMLLLEVDRVLKPGGYFVLT 301
Cdd:cd02440  79 LVEDLARFLEEARRLLKPGGVLVLT 103
PKS_MT smart00828
Methyltransferase in polyketide synthase (PKS) enzymes;
202-305 2.72e-03

Methyltransferase in polyketide synthase (PKS) enzymes;


Pssm-ID: 214839 [Multi-domain]  Cd Length: 224  Bit Score: 39.71  E-value: 2.72e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15222970    202 RTVLDIGCGFGSFGAHLVSLNVMpICIAEYETSGSQVQLALER----GLPAMIGNFF--SKQLPYP-----ALSFDMVHc 270
Cdd:smart00828   1 KRVLDFGCGYGSDLIDLAERHPH-LQLHGYTISPEQAEVGRERiralGLQGRIRIFYrdSAKDPFPdtydlVFGFEVIH- 78

                           90       100       110
                   ....*....|....*....|....*....|....*.
gi 15222970    271 aqcgitwDIKDAM-LLLEVDRVLKPGGYFVLTSPTS 305
Cdd:smart00828  79 -------HIKDKMdLFSNISRHLKDGGHLVLADFIA 107
 
Name Accession Description Interval E-value
Methyltransf_29 pfam03141
Putative S-adenosyl-L-methionine-dependent methyltransferase; This family is a putative ...
 90-598 8.02e-156

Putative S-adenosyl-L-methionine-dependent methyltransferase; This family is a putative S-adenosyl-L-methionine (SAM)-dependent methyltransferase.


Pssm-ID: 335237 [Multi-domain]  Cd Length: 506  Bit Score: 456.77  E-value: 8.02e-156
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15222970    90 NYVPCYNVTES-------------DRNCEFAREEERCLVRPPRDYKIPLRWPVGRDIIWTGNVKITKdqfLSSGTMTKRL 156
Cdd:pfam03141   1 DYIPCLDNKRAikfllsrermehrERHCPPPEEKLNCLVPPPDGYKTPIPWPKSRDKVWYANVPHTK---LAEEKGGQNW 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15222970   157 MLLEENQITFhSDDGLIF-DGVKDYAFQIAEMIglgSDTEFpQAGIRTVLDIGCGFGSFGAHLVSLNVMPICIAEYETSG 235
Cdd:pfam03141  78 VKVEGDKFTF-PGGGTQFpHGADQYIDFIAQMI---PDIAW-GGRVRTALDVGCGVASFGAYLLSRDVLTMSFAPKDVHE 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15222970   236 SQVQLALERGLPAMIGNFFSKQLPYPALSFDMVHCAQCGITWDIKDAMLLLEVDRVLKPGGYFVLTSPTSKAQgnsPDTK 315
Cdd:pfam03141 153 AQVQFALERGIPAMLGVLGTKRLPYPSRSFDLAHCSRCRIPWTANDGILLLEVDRVLRPGGYFVLSGPPVYAR---TEED 229

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15222970   316 KTSISTRVDELSKKICWSLSGQQDETFLWQKTADPNCYSSRSQ-ASIPVCKDDD--SVPYYHPLVPCIS----------G 382
Cdd:pfam03141 230 LQEIWKEMEDLTKSLCWKLVAKKGDIAIWQKPLNNSCYNKREPgKKPPLCKDSDdpDAAWYVPMEACITplpevshevgG 309

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15222970   383 TKSKRWiPiqNRSRASGTSLSELEIHGIKPEEFDEDIQVWRSALKNYWSLLTPLIFSDHpkrpgdedpvppfymIRNAMD 462
Cdd:pfam03141 310 GWPEPW-P--ARLTAVPPRLSSGQIGGVSPESFKADTELWKKRVNKYKRLLKLGIDWGK---------------VRNVMD 371

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15222970   463 MNARYGNLNQALLNQGksVWVMNVVPVKARNTLPIILDRGFTGALHDWCEPFPTYPRTYDMLHANELLTHLsSERCSLMD 542
Cdd:pfam03141 372 MNAGFGGFAAALIDLP--VWVMNVVPVDSPNTLPVIYDRGLIGIYHDWCEAFSTYPRTYDLLHADHLFSLY-KKRCNLVD 448

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 15222970   543 LFLEMDRILRPEGWVVLSDKLGVIEMARTLAARVRWEARVIDIQDGS--DQRLLVCQK 598
Cdd:pfam03141 449 ILLEMDRILRPEGFVIIRDSVDVLDKVKKIAKAMRWEVRMTDTEDGPhvPEKILIAQK 506
UbiE COG2226
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; ...
 202-301 2.37e-10

Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG is part of the Pathway/BioSystem: Biotin biosynthesis


Pssm-ID: 441828 [Multi-domain]  Cd Length: 143  Bit Score: 58.85  E-value: 2.37e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15222970 202 RTVLDIGCGFGSFGAHLVSLNVMPICIaeyETSGSQVQLALERGLPAMIGNFFSK----QLPYPALSFDMVHCAQCGITW 277
Cdd:COG2226  24 ARVLDLGCGTGRLALALAERGARVTGV---DISPEMLELARERAAEAGLNVEFVVgdaeDLPFPDGSFDLVISSFVLHHL 100

                        90       100
                ....*....|....*....|....
gi 15222970 278 DIKDAMLLlEVDRVLKPGGYFVLT 301
Cdd:COG2226 101 PDPERALA-EIARVLKPGGRLVVV 123
Methyltransf_11 pfam08241
Methyltransferase domain; Members of this family are SAM dependent methyltransferases.
 205-300 7.92e-10

Methyltransferase domain; Members of this family are SAM dependent methyltransferases.


Pssm-ID: 462406 [Multi-domain]  Cd Length: 94  Bit Score: 56.13  E-value: 7.92e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15222970   205 LDIGCGFGSFGAHLVSL--NVMPICIAEYETSGSQvQLALERGLPAMIGNFFskQLPYPALSFDMVHCAQCgiTWDIKD- 281
Cdd:pfam08241   1 LDVGCGTGLLTELLARLgaRVTGVDISPEMLELAR-EKAPREGLTFVVGDAE--DLPFPDNSFDLVLSSEV--LHHVEDp 75

                          90
                  ....*....|....*....
gi 15222970   282 AMLLLEVDRVLKPGGYFVL 300
Cdd:pfam08241  76 ERALREIARVLKPGGILII 94
Methyltransf_25 pfam13649
Methyltransferase domain; This family appears to be a methyltransferase domain.
 204-296 1.26e-08

Methyltransferase domain; This family appears to be a methyltransferase domain.


Pssm-ID: 463945 [Multi-domain]  Cd Length: 96  Bit Score: 52.57  E-value: 1.26e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15222970   204 VLDIGCGFGSFGAHLVSLnvmpiCIAEY---ETSGSQVQLALER----GLPA--MIGNFFskQLPYPALSFDMVHCAQCG 274
Cdd:pfam13649   1 VLDLGCGTGRLTLALARR-----GGARVtgvDLSPEMLERARERaaeaGLNVefVQGDAE--DLPFPDGSFDLVVSSGVL 73

                          90       100
                  ....*....|....*....|...
gi 15222970   275 ITWDIKDAMLLL-EVDRVLKPGG 296
Cdd:pfam13649  74 HHLPDPDLEAALrEIARVLKPGG 96
UbiG COG2227
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and ...
 202-303 6.29e-07

2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and metabolism]; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 441829 [Multi-domain]  Cd Length: 126  Bit Score: 48.48  E-value: 6.29e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15222970 202 RTVLDIGCGFGSFGAHLVSLNvmpiciAEY---ETSGSQVQLALERGLPAMI----GNFFskQLPYPALSFDMVHCAQCg 274
Cdd:COG2227  26 GRVLDVGCGTGRLALALARRG------ADVtgvDISPEALEIARERAAELNVdfvqGDLE--DLPLEDGSFDLVICSEV- 96

                        90       100
                ....*....|....*....|....*....
gi 15222970 275 ITWDIKDAMLLLEVDRVLKPGGYFVLTSP 303
Cdd:COG2227  97 LEHLPDPAALLRELARLLKPGGLLLLSTP 125
Methyltransf_31 pfam13847
Methyltransferase domain; This family appears to have methyltransferase activity.
 203-308 3.38e-06

Methyltransferase domain; This family appears to have methyltransferase activity.


Pssm-ID: 463998 [Multi-domain]  Cd Length: 150  Bit Score: 47.03  E-value: 3.38e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15222970   203 TVLDIGCGFGSFGAHLVSLNVMPICIAEYETSGSQVQLALER-------GLPAMIGNFFSKQLPYPALSFDMVHCAQCGI 275
Cdd:pfam13847   6 RVLDLGCGTGHLSFELAEELGPNAEVVGIDISEEAIEKARENaqklgfdNVEFEQGDIEELPELLEDDKFDVVISNCVLN 85

                          90       100       110
                  ....*....|....*....|....*....|...
gi 15222970   276 TWDIKDAmLLLEVDRVLKPGGYFVLTSPTSKAQ 308
Cdd:pfam13847  86 HIPDPDK-VLQEILRVLKPGGRLIISDPDSLAE 117
COG4976 COG4976
Predicted methyltransferase, contains TPR repeat [General function prediction only];
195-309 1.31e-05

Predicted methyltransferase, contains TPR repeat [General function prediction only];


Pssm-ID: 444001 [Multi-domain]  Cd Length: 181  Bit Score: 46.14  E-value: 1.31e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15222970 195 EFPQAGIRTVLDIGCGFGSFGAHLVSlnvMPICIAEYETSGSQVQLALERGLPA--MIGNFFskQLPYPALSFDMVhCAQ 272
Cdd:COG4976  41 RLPPGPFGRVLDLGCGTGLLGEALRP---RGYRLTGVDLSEEMLAKAREKGVYDrlLVADLA--DLAEPDGRFDLI-VAA 114

                        90       100       110
                ....*....|....*....|....*....|....*....
gi 15222970 273 CGITW--DIKDamLLLEVDRVLKPGGYFVLTSPTSKAQG 309
Cdd:COG4976 115 DVLTYlgDLAA--VFAGVARALKPGGLFIFSVEDADGSG 151
PLN02244 PLN02244
tocopherol O-methyltransferase
 197-331 8.03e-05

tocopherol O-methyltransferase


Pssm-ID: 215135 [Multi-domain]  Cd Length: 340  Bit Score: 45.12  E-value: 8.03e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15222970  197 PQAGIRTVLDIGCGFGSFGAHLV---SLNVMPICIAEYETSGSQvQLALERGLpamiGNFFSKQ------LPYPALSFDM 267
Cdd:PLN02244 115 DEKRPKRIVDVGCGIGGSSRYLArkyGANVKGITLSPVQAARAN-ALAAAQGL----SDKVSFQvadalnQPFEDGQFDL 189

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 15222970  268 VHCAQCGITWDIKdAMLLLEVDRVLKPGGYFVLTSPTSKaqgnspDTKKTSISTRVDELS--KKIC 331
Cdd:PLN02244 190 VWSMESGEHMPDK-RKFVQELARVAAPGGRIIIVTWCHR------DLEPGETSLKPDEQKllDKIC 248
AdoMet_MTases cd02440
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ...
 203-301 1.23e-04

S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).


Pssm-ID: 100107 [Multi-domain]  Cd Length: 107  Bit Score: 41.65  E-value: 1.23e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15222970 203 TVLDIGCGFGSFGAHLVSLNvmPICIAEYETSGSQVQLALERGLPAMIGNF------FSKQLPYPALSFDMVHCAQCGIT 276
Cdd:cd02440   1 RVLDLGCGTGALALALASGP--GARVTGVDISPVALELARKAAAALLADNVevlkgdAEELPPEADESFDVIISDPPLHH 78

                        90       100
                ....*....|....*....|....*
gi 15222970 277 WDIKDAMLLLEVDRVLKPGGYFVLT 301
Cdd:cd02440  79 LVEDLARFLEEARRLLKPGGVLVLT 103
SmtA COG0500
SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, ...
 202-311 1.98e-04

SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, General function prediction only];


Pssm-ID: 440266 [Multi-domain]  Cd Length: 199  Bit Score: 42.98  E-value: 1.98e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15222970 202 RTVLDIGCGFGSFGAHLVSLNVMP-ICIaeyETSGSQVQLALERGLPAMIGN--F----FSKQLPYPALSFDMVHCAQCg 274
Cdd:COG0500  28 GRVLDLGCGTGRNLLALAARFGGRvIGI---DLSPEAIALARARAAKAGLGNveFlvadLAELDPLPAESFDLVVAFGV- 103

                        90       100       110
                ....*....|....*....|....*....|....*....
gi 15222970 275 ITW--DIKDAMLLLEVDRVLKPGGYFVLtSPTSKAQGNS 311
Cdd:COG0500 104 LHHlpPEEREALLRELARALKPGGVLLL-SASDAAAALS 141
Cfa COG2230
Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport ...
 203-303 4.94e-04

Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport and metabolism];


Pssm-ID: 441831 [Multi-domain]  Cd Length: 158  Bit Score: 41.07  E-value: 4.94e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15222970 203 TVLDIGCGFGSF--------GAHLVSLNVmpiciaeyetsgSQVQLAL------ERGLPAMI----GNFFskQLPYPAlS 264
Cdd:COG2230  54 RVLDIGCGWGGLalylarryGVRVTGVTL------------SPEQLEYareraaEAGLADRVevrlADYR--DLPADG-Q 118

                        90       100       110       120
                ....*....|....*....|....*....|....*....|
gi 15222970 265 FDMVHCAQCGITWDIKDAMLLLE-VDRVLKPGGYFVLTSP 303
Cdd:COG2230 119 FDAIVSIGMFEHVGPENYPAYFAkVARLLKPGGRLLLHTP 158
PRK10258 PRK10258
biotin biosynthesis protein BioC; Provisional
 197-313 1.78e-03

biotin biosynthesis protein BioC; Provisional


Pssm-ID: 182340 [Multi-domain]  Cd Length: 251  Bit Score: 40.51  E-value: 1.78e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15222970  197 PQAGIRTVLDIGCGFGSF-------GAHLVSLNVMPICIAEyetsgSQVQLALERGLPAMIgnffsKQLPYPALSFDMV- 268
Cdd:PRK10258  39 PQRKFTHVLDAGCGPGWMsrywrerGSQVTALDLSPPMLAQ-----ARQKDAADHYLAGDI-----ESLPLATATFDLAw 108

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 15222970  269 -HCAqcgITW--DIKDAmlLLEVDRVLKPGGYFVLtspTSKAQGNSPD 313
Cdd:PRK10258 109 sNLA---VQWcgNLSTA--LRELYRVVRPGGVVAF---TTLVQGSLPE 148
Methyltransf_12 pfam08242
Methyltransferase domain; Members of this family are SAM dependent methyltransferases.
 205-298 1.81e-03

Methyltransferase domain; Members of this family are SAM dependent methyltransferases.


Pssm-ID: 400515 [Multi-domain]  Cd Length: 98  Bit Score: 38.12  E-value: 1.81e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15222970   205 LDIGCGFGSFGAHLVSLNvmpiCIAEY---ETSGSQVQLALER-----GLPAMIGNFFSKQLPYPAL-SFDMVHCAQC-G 274
Cdd:pfam08242   1 LEIGCGTGTLLRALLEAL----PGLEYtglDISPAALEAARERlaalgLLNAVRVELFQLDLGELDPgSFDVVVASNVlH 76

                          90       100
                  ....*....|....*....|....
gi 15222970   275 ITWDIKDAmlLLEVDRVLKPGGYF 298
Cdd:pfam08242  77 HLADPRAV--LRNIRRLLKPGGVL 98
PKS_MT smart00828
Methyltransferase in polyketide synthase (PKS) enzymes;
202-305 2.72e-03

Methyltransferase in polyketide synthase (PKS) enzymes;


Pssm-ID: 214839 [Multi-domain]  Cd Length: 224  Bit Score: 39.71  E-value: 2.72e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15222970    202 RTVLDIGCGFGSFGAHLVSLNVMpICIAEYETSGSQVQLALER----GLPAMIGNFF--SKQLPYP-----ALSFDMVHc 270
Cdd:smart00828   1 KRVLDFGCGYGSDLIDLAERHPH-LQLHGYTISPEQAEVGRERiralGLQGRIRIFYrdSAKDPFPdtydlVFGFEVIH- 78

                           90       100       110
                   ....*....|....*....|....*....|....*.
gi 15222970    271 aqcgitwDIKDAM-LLLEVDRVLKPGGYFVLTSPTS 305
Cdd:smart00828  79 -------HIKDKMdLFSNISRHLKDGGHLVLADFIA 107
PRK08317 PRK08317
hypothetical protein; Provisional
 203-300 5.01e-03

hypothetical protein; Provisional


Pssm-ID: 181382 [Multi-domain]  Cd Length: 241  Bit Score: 39.15  E-value: 5.01e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15222970  203 TVLDIGCGFGSF----------GAHLVSLNVMP--ICIAEYETSGSQVQLALERGLPAmignffskQLPYPALSFDMV-- 268
Cdd:PRK08317  22 RVLDVGCGPGNDarelarrvgpEGRVVGIDRSEamLALAKERAAGLGPNVEFVRGDAD--------GLPFPDGSFDAVrs 93

                         90       100       110
                 ....*....|....*....|....*....|....
gi 15222970  269 -HCAQCgitwdIKD-AMLLLEVDRVLKPGGYFVL 300
Cdd:PRK08317  94 dRVLQH-----LEDpARALAEIARVLRPGGRVVV 122
Tam COG4106
Trans-aconitate methyltransferase [Energy production and conversion];
202-301 5.40e-03

Trans-aconitate methyltransferase [Energy production and conversion];


Pssm-ID: 443282 [Multi-domain]  Cd Length: 100  Bit Score: 36.73  E-value: 5.40e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15222970 202 RTVLDIGCGFGSFGAHLVSLNVMPICIAeYETSGSQVQLALER--GLPAMIGNFFSKQLPYPalsFDMVHCAQCgITWdI 279
Cdd:COG4106   3 RRVLDLGCGTGRLTALLAERFPGARVTG-VDLSPEMLARARARlpNVRFVVADLRDLDPPEP---FDLVVSNAA-LHW-L 76

                        90       100
                ....*....|....*....|...
gi 15222970 280 KDAMLLLE-VDRVLKPGGYFVLT 301
Cdd:COG4106  77 PDHAALLArLAAALAPGGVLAVQ 99
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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