|
Name |
Accession |
Description |
Interval |
E-value |
| PLN00136 |
PLN00136 |
silicon transporter; Provisional |
1-501 |
0e+00 |
|
silicon transporter; Provisional
Pssm-ID: 215070 [Multi-domain] Cd Length: 482 Bit Score: 596.59 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42561620 1 MAMAPVIKLVLGSVAFAIFWILAVFPSVPFLPIGRTAGSLFGAMLMVIFQVITPEQAYAAIDLPILGLLFGTMVVSIYLE 80
Cdd:PLN00136 1 MALASLPKVVLGSLAFGVFWMLAVFPSVPFLPIGRTAGALLSAVLMIVFHVISPDDAYASIDLPILGLLFATMVVGSYLK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42561620 81 RADMFKYLGTLLSWKSRGPKDLLCRVCLVSAVSSALFTNDTSCVVLTEFVLKIARQKNLPPHPFLLALATSANIGSSATP 160
Cdd:PLN00136 81 NAGMFKHLGRLLAWRSQGGRDLLCRVCVVTALASALFTNDTCCVVLTEFVLELAAERNLPAKPFLLALASSANIGSSATP 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42561620 161 IGNPQNLVIAVQSKIPFWEFLLGVFPAMIVGITVNAMLLLGMYWRllsdhkedeeEVQNADsevvaqedvqshrfspatf 240
Cdd:PLN00136 161 IGNPQNLVIAFNSKITFPKFLLGILPAMLAGMAVNMVMLLCMYWK----------DLDGGA------------------- 211
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42561620 241 spvSSEDSNLRMDAAETLRNRAGSAGESELISCNSNASREqhNDAESQGESNNTNNMFQTKRW--------RRVLWKSSV 312
Cdd:PLN00136 212 ---ELSVDGKQMEAVEEGRSPASAKSTKQQSPALLQAGLN--GDGNGDMSSMMSENISTKHPWfmqctehrRKLFLKSFA 286
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42561620 313 YFITLGMLISLLMGLNMSWTAITAALALVVLDFKDARPSLEKVSYSLLIFFCGMFITVDGFNKTGIPTALWDLMEPYAKI 392
Cdd:PLN00136 287 YVVTVGMVVAYMVGLNMSWTAITTAIALVVVDFRDAEPCLDTVSYSLLVFFSGMFITVSGFNKTGLPGAIWNFMAPYSKV 366
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42561620 393 DQAKGIAVLAVVILVLSNVASNVPTVLLLGARVAASA--MGREEEKKAWLLLAWVSTVAGNLTLLGSAANLIVCEQARRA 470
Cdd:PLN00136 367 NSVGGISVLSVIILLLSNLASNVPTVLLMGDEVAAAAalISPAAVTRSWLLLAWVSTVAGNLSLLGSAANLIVCEQARRA 446
|
490 500 510
....*....|....*....|....*....|.
gi 42561620 471 VSHGYTLTFTKHFKFGLPSTLIVTAIGLFLI 501
Cdd:PLN00136 447 PRNAYDLTFWQHIVFGVPSTLIVTAIGIPLI 477
|
|
| YbiR_permease |
cd01117 |
Putative anion permease YbiR. Based on sequence similarity, YbiR proteins are predicted to ... |
28-501 |
1.14e-120 |
|
Putative anion permease YbiR. Based on sequence similarity, YbiR proteins are predicted to function as anion translocating permeases in eubacteria, archaea and plants. They belong to ArsB/NhaD superfamily of permeases that have been shown to translocate sodium, sulfate, arsenite and organic anions. A typical ArsB/NhaD permease is composed of 8-13 transmembrane domains.
Pssm-ID: 238537 [Multi-domain] Cd Length: 384 Bit Score: 358.90 E-value: 1.14e-120
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42561620 28 VPFLPIGRTAGSLFGAMLMVIFQVITPEQAYAAIDLPILGLLFGTMVVSIYLERADMFKYLGTLLSWKSRGPKDLLCRVC 107
Cdd:cd01117 6 VPGLRLDRWAIALLGAALMLLFGVISLEDAPAAIDLDTIILLFGLMVVSAALELSGFFDALGSRILVKAGSPRRLLFLLV 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42561620 108 LVSAVSSALFTNDTSCVVLTEFVLKIARQKNLPPHPFLLALATSANIGSSATPIGNPQNLVIAVQSKIPFWEFLLGVFPA 187
Cdd:cd01117 86 LLSGILSALLTNDTACLVFTPIVLELARVAGLPPIPLLLALATAANIGSAATPIGNPQNLLIASESGISFPFFLAAMAPL 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42561620 188 MIVGITVNAMLLLGMYWRLLSdhkedeeevqnadsevvaqedvqshrfspatfspvssedsnlrmdaaetlrnragsage 267
Cdd:cd01117 166 ALLGLLLLLILLLVLFPGELK----------------------------------------------------------- 186
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42561620 268 seliscnsnasreqhndaesqGESNNTNNMFQTKRWRRVLWKSSVYFITLGMLISLLMGLNMSWTAITAALALVVLDFKD 347
Cdd:cd01117 187 ---------------------GLPLDKATKEEGVGARKLAVKLLVLILLLLVAFLALLGVIPLWTAALVAAVLLLLTRLK 245
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42561620 348 ARPSLEKVSYSLLIFFCGMFITVDGFNkTGIPTALWDLMEPYakidqAKGIAVLAVVILVLSNVASNVPTVLLLGARVAA 427
Cdd:cd01117 246 PRRVLKKVDWGLLLFFAGLFILVGGFA-QGLPLEGLSRLLPL-----LDSVLSLFLVSIGLSQLISNVPAVLLLLPFLPS 319
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 42561620 428 SAmgreeeKKAWLLLAWVSTVAGNLTLLGSAANLIVCEQARRAvshGYTLTFTKHFKFGLPSTLIVTAIGLFLI 501
Cdd:cd01117 320 AD------EKDWLLLAAGSTIAGNLTLLGSAANLIVAEAAERR---GVRLSFGEFLKYGVPLTLLTAAIGILWL 384
|
|
| ArsB_NhaD_permease |
cd00625 |
Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, ... |
30-501 |
8.50e-79 |
|
Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life. A typical anion permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a channel-forming subunit of an ATP-driven anion pump.
Pssm-ID: 238344 [Multi-domain] Cd Length: 396 Bit Score: 251.40 E-value: 8.50e-79
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42561620 30 FLPIGRTAGSLFGAMLMVIFQVITPEQAYAAIDLPILGLLFGTMVVSIYLERADMFKYLGTLLSWKSRGPKDLLCRVCLV 109
Cdd:cd00625 6 PEKLPRAVVALLGAVLLVLLGVVSPKEALSAIDWETILLLFGMMILSAALEETGLFDRLAAKLARASKGSRRLLLLLMLL 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42561620 110 SAVSSALFTNDTSCVVLTEFVLKIARQKNLPPH-PFLLALATSANIGSSATPIGNPQNLVIAVQSKIPFWEFLLGVFPAM 188
Cdd:cd00625 86 TAALSAFFSNDATAVLLTPIVLALLRKLGLSPPvPLLLALAFAANIGGAATPIGNPPNLIIASLSGLGFLDFLAFMAPPA 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42561620 189 IVGITVNAMLLLGMYWRLLSDHKEDEEEVQNADSEVVAQedvqshrfspatfspvssedsnlrmdaaetlrnragsages 268
Cdd:cd00625 166 LGLLLLLLGLLYLLFRKKLLLPDEDKLTVLAEPLPARPL----------------------------------------- 204
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42561620 269 eliscnsnasreqhndaesqgesnntnnmfqtkRWRRVLWKSSVYFITLGMLISLlmGLNMSWTAITAALALVVLDF-KD 347
Cdd:cd00625 205 ---------------------------------LKKFLLLALLLLLLFVLLFFFL--IPLGLIALLGALLLLLLLVRgLD 249
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42561620 348 ARPSLEKVSYSLLIFFCGMFITVDGFNKTGIPTALWDLMEPYAKIDQAKGIAVLAVVILVLSNVASNVPTVLLLGARVAA 427
Cdd:cd00625 250 PEEVLKSVDWGTLLFFAGLFVLVGALESTGLLEWLAELLVALVGLPPLAALLLIGLLSALLSNFISNVPTVALLLPIAAS 329
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 42561620 428 SAMGReeekKAWLLLAWVSTVAGNLTLLGSAANLIVCEQARRavsHGYTLTFTKHFKFGLPSTLIVTAIGLFLI 501
Cdd:cd00625 330 LAPPE----PAWLALALGSTLGGNLTLIGSLANLIPLGAAEN---AGVGISFGEFLKVGLPLTLLSLVVSLLYL 396
|
|
| ArsB |
COG1055 |
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism]; |
33-501 |
7.40e-78 |
|
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism];
Pssm-ID: 440675 [Multi-domain] Cd Length: 415 Bit Score: 249.66 E-value: 7.40e-78
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42561620 33 IGRTAGSLFGAMLMVIFQVITPEQAYAAIDLPILGLLFGTMVVSIYLERADMFKYLGTLLSWKSRGPKD-LLCRVCLVSA 111
Cdd:COG1055 23 LNRAVAALLGAALLLLLGVVSLEDALEAIDWNTILFLLGMMIIVAILDESGFFEWLAIKLARRAKGSPRrLLWLLGLLTA 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42561620 112 VSSALFTNDTSCVVLTEFVLKIARQKNLPPHPFLLALATSANIGSSATPIGNPQNLVIAVQSKIPFWEFLLGVFPAMIVG 191
Cdd:COG1055 103 LLSAFLDNDTTALLLTPVVLAIARRLGLNPVPFLIAIVFAANIGGAATPIGNPTNIMIASAGGLSFLDFLANLFPPSLVS 182
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42561620 192 ITVNAMLLLGMYWRLLSDHKEDEEevqnadsevvaqedvqshrfspatfspvssedsnlrmDAAETLRNragsageseli 271
Cdd:COG1055 183 LLVTLLVLYLLFRKELPAAPDLED-------------------------------------DPKEAIKD----------- 214
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42561620 272 scnsnasreqhndaesqgesnntnnmfqtkrwRRVLWKSSVYFITL--GMLISLLMGLNMSWTAITAALALVVLDFKDAR 349
Cdd:COG1055 215 --------------------------------RRLLRISLLVLALLlvGFVLHSFLGLPPALIALLGAAVLLLLARVDVR 262
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42561620 350 PSLEKVSYSLLIFFCGMFITVDGFNKTGIPTALWDLMEPYAKIDQAKGIAVLAVVILVLSNVASNVPTVLLLGARVAASA 429
Cdd:COG1055 263 EVLKKVDWSTLLFFIGLFVVVGGLENTGLLDLLAELLASLTGGNLLLAALLILWLSAILSAVVDNVPLVAALLPLIPDLG 342
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 42561620 430 MGREEEkKAWLLLAWVSTVAGNLTLLGSAANLIVCEQARRavsHGYTLTFTKHFKFGLPSTLIVTAIGLFLI 501
Cdd:COG1055 343 ATGNPE-PLWLALALGATLGGNLTPIGSAANVIVLGIAEK---KGIKISFGEFLKVGLPLTLLTLLIALLYL 410
|
|
| CitMHS |
pfam03600 |
Citrate transporter; |
32-449 |
1.25e-66 |
|
Citrate transporter;
Pssm-ID: 460985 [Multi-domain] Cd Length: 342 Bit Score: 218.34 E-value: 1.25e-66
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42561620 32 PIGRTAGSLFGAMLMVIFQVITPEQAYAAIDLPILGLLFGTMVVSIYLERADMFKYLGTLLSWKSRG-PKDLLCRVCLVS 110
Cdd:pfam03600 8 KLPRDVVALLGAVLLVLLGVLTPEEALSGIDSPTILLLLGMMIIGAILERTGLFDRLALKLLRLAGGkPRRLLVALMLAT 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42561620 111 AVSSALFTNDTSCVVLTEFVLKIARQKNLPPHPFLLALATSANIGSSATPIGNPQNLVIAVQSKIPFWEFLLGVFPAMIV 190
Cdd:pfam03600 88 ALLSAFLSNDGTVLIMIPIVLALARRLGLPPSPLLIALAFAANIGGTATPIGDPPNIIIASALGLSFGDFGFFMFPPVGV 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42561620 191 GITVNAML-LLGMYWRLLSDHKEDEEEVQNADSevvaqedvqshrfspatfspvssedsnlrmdaaetlrnragsagese 269
Cdd:pfam03600 168 ALLLVGLLpLLLIFRKLLPVRKEEEAELEELRK----------------------------------------------- 200
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42561620 270 liscnsnasreqhndaesqgesnntnnmfQTKRWRRVLWKSSVYFITLGMLISLLMGLNMSWtaitaALALVVLDFKDAR 349
Cdd:pfam03600 201 -----------------------------RAIKDKLLLAISALVLALVILGFLLLSVLALAG-----ALLLLLTGVLDPE 246
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42561620 350 PSLEKVSYSLLIFFCGMFITVDGFNKTGIPTALWDLMEPYAKIdqAKGIAVLAVVILVLSNVASNVPTVLLLGARVAASA 429
Cdd:pfam03600 247 EALKAVDWSTLLFFAGLFILVGALEKTGLADALADALGGLSGL--LVALALILWLSALLSAFISNVPTAALMAPIIVGMA 324
|
410 420
....*....|....*....|
gi 42561620 430 MGreEEKKAWLLLAWVSTVA 449
Cdd:pfam03600 325 PA--AGLGDPDPLAWALAVG 342
|
|
| P_permease |
cd01116 |
Permease P (pink-eyed dilution). Mutations in the human melanosomal P gene were responsible ... |
33-501 |
1.01e-42 |
|
Permease P (pink-eyed dilution). Mutations in the human melanosomal P gene were responsible for classic phenotype of oculocutaneous albinism type 2 (OCA2). Although the precise function of the P protein is unknown, it was predicted to regulate the intraorganelle pH, together with the ATP-driven proton pump. It shows significant sequence similarity to the Na+/H+ antiporter NhaD from Vibrio parahaemolyticus. Both proteins belong to ArsB/NhaD superfamily of permeases that translocate sodium, arsenate, sulfate, and organic anions across biological membranes in all three kingdoms of life. A typical ArsB/NhaD permease contains 8-13 transmembrane domains.
Pssm-ID: 238536 [Multi-domain] Cd Length: 413 Bit Score: 156.64 E-value: 1.01e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42561620 33 IGRTAGSLFGAMLMVIFQVI----TPEQAYAAIDLPILGLLFGTMVVSIYLERADMFKYLGTLLSWKSRG-PKDLLCRVC 107
Cdd:cd01116 13 VHRTVAALAGALWLVILGLAtlspDLETIVSWVDWETLALLLGMMIIVSILSETGVFEYLAIWAVKISKGrPWRLLLLLG 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42561620 108 LVSAVSSALFTNDTSCVVLTEFVLKIARQKNLPPHPFLLALATSANIGSSATPIGNPQNLVIAVQSKIPFWEFLLGVFPA 187
Cdd:cd01116 93 LLTAFLSAFLDNVTTVLLMVPVTIRLCEVLGLNPVPVLISEVIAANIGGAATLIGDPPNIMIGSAAGLTFNDFLLHMLPS 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42561620 188 MIVGITVNAMLLLGMYWRLLSDHKEDEEEVQNADsevvaqedvqshrfspatfspvssedsnlrmdaaetlrnragsage 267
Cdd:cd01116 173 VVLALVVTFILLYFLYRNILKAREEDVLALAELE---------------------------------------------- 206
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42561620 268 seliscnsnaSREQHNDaesqgesnntnnmfqtkrwRRVLWKSSV--YFITLGMLISLLMGLNMSWTAITAALALVVLDF 345
Cdd:cd01116 207 ----------PKYPIKD-------------------KVLLLKSLTilTLVIIGFVLHSPLGVSLGWIALLGALLLLLLAD 257
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42561620 346 KDARPS-LEKVSYSLLIFFCGMFITVDGFNKTGIPTALWDLMEPYAKIDQAKGIAVLAVVILVLSNVASNVPTV-----L 419
Cdd:cd01116 258 KLDFEDvLSRVEWDTLLFFAGLFVLVGGLEELGIIEWIAELLVGVILGRIAVAVILILWISALLSAFIDNIPVTatmipI 337
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42561620 420 LLGARVAASAMGREeekkAWLLLAWVSTVAGNLTLLGSAANLIVCEQARRavsHGYTLTFTKHFKFGLPSTLI-VTAIGL 498
Cdd:cd01116 338 VKDLASQLGIPLLP----LWWALALGACLGGNGTLIGASANVVAAGIAEQ---HGYKISFWEFLKVGFPIMLVsLILATV 410
|
...
gi 42561620 499 FLI 501
Cdd:cd01116 411 YLL 413
|
|
| ArsB_permease |
cd01118 |
Anion permease ArsB. These permeases have been shown to export arsenate and antimonite in ... |
15-499 |
4.12e-24 |
|
Anion permease ArsB. These permeases have been shown to export arsenate and antimonite in eubacteria and archaea. A typical ArsB permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a channel-forming subunit of an ATP-driven anion pump (ArsAB). The ArsAB complex is similar in many ways to ATP-binding cassette transporters, which have two groups of six transmembrane-spanning helical segments and two nucleotide-binding domains. The ArsB proteins belong to the ArsB/NhaD superfamily of permeases that translocate sodium, arsenate, sulfate, and organic anions across biological membranes in all three kingdoms of life.
Pssm-ID: 238538 [Multi-domain] Cd Length: 416 Bit Score: 104.27 E-value: 4.12e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42561620 15 AFAIFWILAVFPSV-PF-LPIGRTAgsLFGAMLMVIFQVITPEQAYAAID--LPILGLLFGTMVVSIYLERADMFKYLGT 90
Cdd:cd01118 2 AIAIFVLTLVLVIWrPFgLPEAVWA--VLGAVIALILGLVSPHDALEVWGivWDVTLTLIGVILLSLLLDEEGFFEWVAA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42561620 91 LLSWKSRG-PKDLLCRVCLVSAVSSALFTNDTSCVVLTEFVLKIARQKNLPPH---PFLLALATSANIGSSATPIGNPQN 166
Cdd:cd01118 80 LAARWARGsGRKLFTLIVLLGAAVTAFFANDGTALILTPIVIALLRALGAKKNrtlPFLYACAFIADAASLPLPISNLVN 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42561620 167 LVIAVQSKIPFWEFLLGVFPAMIVGItvnAMLLLGMYWRLlsdhkedeeevqnadsevvaqedvqsHRFSPATFSPVSSE 246
Cdd:cd01118 160 IVTAGYFGIGFTEYAALMFLPSIVSI---LATYVVLYLFF--------------------------RRALPKRLETASVK 210
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42561620 247 DSNLRMDAaetlrnragsageseliscnsnasreqhndaesqgesnntnnmfqtkrwrRVLWKSSVYFITLGMLISLLMG 326
Cdd:cd01118 211 KPSLAIKD--------------------------------------------------PLLFGLAWTLLVLLVVSAFGVD 240
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42561620 327 LNMS-WTAITAALALVVL------DFKDARPSLEKVSYSLLIFFCGMFITVDGFNKTGIPTALWDLMEPYAKIDQAKGIA 399
Cdd:cd01118 241 ILLIpPSFIAGVLALIFLllarrgGAINPLKVLKEAPWGVLLFSLGLYVVVFGLKNAGLTAILADLLNWLVSQGLLAAIL 320
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42561620 400 VLAVVILVLSNVASNVPTVlLLGARVAASAMGREEEKKAWLLlawVSTVAGNLTLLGSAANLIVCEQARRavsHGYTLTF 479
Cdd:cd01118 321 GVGLLAAFLSNVMNNLPAV-LIGALALAAGHAPEALVYANLI---GVDLGPKLTPIGSLATLLWLHVLRR---KGIRVSW 393
|
490 500
....*....|....*....|
gi 42561620 480 TKHFKFGLPSTLIVTAIGLF 499
Cdd:cd01118 394 GYYLKVGLIVTPPVLVVTLA 413
|
|
| CitT |
COG0471 |
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism]; |
8-206 |
1.31e-14 |
|
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism];
Pssm-ID: 440239 [Multi-domain] Cd Length: 369 Bit Score: 75.19 E-value: 1.31e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42561620 8 KLVLGSVAFAIFwiLAVFPSVPFLPIgrTAGSLFGAMLMVIFQVITPEQAYAAIDLPILGLLFGTMVVSIYLERADMFKY 87
Cdd:COG0471 175 KIALAIFALTVL--LWITGSLHGIPI--AVVALLGAVLLLLTGVLTWKDAYKSIPWGVLLLFGGGLALGAALEKTGLAAW 250
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42561620 88 LGTLLSWKSRG--PKDLLCRVCLVSAVSSALFTNDTSCVVLTEFVLKIARQKNLPPHPFLLALATSANiGSSATPIGNPQ 165
Cdd:COG0471 251 LADALLPLLGGlsPLLLLLLLALLTLLLTEFASNTATAALLLPIAISLAQALGVNPLPLALAVAFAAS-CAFLLPVGTPP 329
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 42561620 166 NLVIAVQSKIPFWEFLLGVFPAMIVGITVnAMLLLGMYWRL 206
Cdd:COG0471 330 NAIVYGSGYYKFKDFLKVGLPLNLIGLVV-LLLLGPLWWPL 369
|
|
| CitT |
COG0471 |
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism]; |
70-501 |
3.34e-14 |
|
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism];
Pssm-ID: 440239 [Multi-domain] Cd Length: 369 Bit Score: 74.04 E-value: 3.34e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42561620 70 FGTMVVSIYLERADMFKYLG-TLLSWKSRGPKDLLCRVCLVSAVSSALFTNDTSCVVLTEFVLKIARQ-----KNLPPHP 143
Cdd:COG0471 1 LGGFVLAAALEKTGLGRRIAlLLLKRFGGSPLRLLLGLMLATALLSAFISNTARAAMMLPIALSIAAAlgsekRSKFGSA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42561620 144 FLLALATSANIGSSATPIGNPQNLVIA------VQSKIPFWEFLLGVFPAMIVGITVnamLLLGMYWRLLSDHKEDEeev 217
Cdd:COG0471 81 LLLPIAFAASIGGMGTLIGTPPNLIAAglleeaTGIPISFFEWMLVGLPVALVGLLL---LWLVLYRLLPPEIKEVP--- 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42561620 218 qnadsevvaqedvqshrfspatfspvssedsnlrmDAAETLRNRAGSAGeseliscnsnasreqhndaesqgesnntnnm 297
Cdd:COG0471 155 -----------------------------------GSKEVIREELAELG------------------------------- 168
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42561620 298 fqtkRWRRVLWKSSVYFIT--LGMLISLLMGLNMSWTAITAALALV---VLDFKDARpslEKVSYSLLIFFCGMFITVDG 372
Cdd:COG0471 169 ----PLSRREKIALAIFALtvLLWITGSLHGIPIAVVALLGAVLLLltgVLTWKDAY---KSIPWGVLLLFGGGLALGAA 241
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42561620 373 FNKTGIPTALWDLMEPY-AKIDQAKGIAVLAVVILVLSNVASNVPTVLLLGARVAASAMGREEEKKAWLLLAWVSTVAGN 451
Cdd:COG0471 242 LEKTGLAAWLADALLPLlGGLSPLLLLLLLALLTLLLTEFASNTATAALLLPIAISLAQALGVNPLPLALAVAFAASCAF 321
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|
gi 42561620 452 LTLLGSAANLIVceqarraVSHGYtLTFTKHFKFGLPSTLIVTAIGLFLI 501
Cdd:COG0471 322 LLPVGTPPNAIV-------YGSGY-YKFKDFLKVGLPLNLIGLVVLLLLG 363
|
|
| SLC13_permease |
cd01115 |
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been ... |
31-192 |
3.93e-13 |
|
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is related to renal and intestinal Na+/sulfate cotransporters and a few putative bacterial permeases. The SLC13-type proteins belong to the ArsB/NhaD superfamily of permeases that translocate sodium and various anions across biological membranes in all three kingdoms of life. A typical ArsB/NhaD permease is composed of 8-13 transmembrane helices.
Pssm-ID: 238535 [Multi-domain] Cd Length: 382 Bit Score: 70.69 E-value: 3.93e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42561620 31 LPIGRTAgsLFGAMLMVIFQVITPEQAYAAIDLPILGLLFGTMVVSIYLERADMFKYLGTLLSWK-SRGPKDLLCRVCLV 109
Cdd:cd01115 16 LPLDVTA--LLVPVLLVLLGVVPPKEAFSGFSDPAVILFLAGFILGAALTRTGLAKRIATKLLKRaGKGERRLLLLLMLV 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42561620 110 SAVSSALFTNDTSCVVLTEFVLKIARQKNLPPHPFLLALATSANIGSSATPIGNPQNLVI-AVQSKIPFWEFLLGVF--- 185
Cdd:cd01115 94 TAFLSAFMSNTATVAIMLPVALGLAAKLDISPSRLLMPLAFAASIGGMLTLIGTPPNLVAsGYLESLGGQGFSFFEFtpi 173
|
....*....
gi 42561620 186 --PAMIVGI 192
Cdd:cd01115 174 glPLLIIGL 182
|
|
| P_permease |
cd01116 |
Permease P (pink-eyed dilution). Mutations in the human melanosomal P gene were responsible ... |
9-200 |
8.88e-12 |
|
Permease P (pink-eyed dilution). Mutations in the human melanosomal P gene were responsible for classic phenotype of oculocutaneous albinism type 2 (OCA2). Although the precise function of the P protein is unknown, it was predicted to regulate the intraorganelle pH, together with the ATP-driven proton pump. It shows significant sequence similarity to the Na+/H+ antiporter NhaD from Vibrio parahaemolyticus. Both proteins belong to ArsB/NhaD superfamily of permeases that translocate sodium, arsenate, sulfate, and organic anions across biological membranes in all three kingdoms of life. A typical ArsB/NhaD permease contains 8-13 transmembrane domains.
Pssm-ID: 238536 [Multi-domain] Cd Length: 413 Bit Score: 66.89 E-value: 8.88e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42561620 9 LVLGSVAFAIFWILAVFPSVPFLPIGRTAGSlfGAMLMVIF-QVITPEQAYAAIDLPILgLLFGTMVVSIY-LERADMFK 86
Cdd:cd01116 217 LLKSLTILTLVIIGFVLHSPLGVSLGWIALL--GALLLLLLaDKLDFEDVLSRVEWDTL-LFFAGLFVLVGgLEELGIIE 293
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42561620 87 YLGTLLSWKSRGPKDLLCRVCL-VSAVSSALFTNDTSCVVLTEFVLKIARQKNLPPHPFLLALATSANIGSSATPIGNPQ 165
Cdd:cd01116 294 WIAELLVGVILGRIAVAVILILwISALLSAFIDNIPVTATMIPIVKDLASQLGIPLLPLWWALALGACLGGNGTLIGASA 373
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 42561620 166 NLVIAVQS-----KIPFWEFLLGVFPAMIVGITVNAMLLL 200
Cdd:cd01116 374 NVVAAGIAeqhgyKISFWEFLKVGFPIMLVSLILATVYLL 413
|
|
| ArsB |
COG1055 |
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism]; |
16-204 |
1.02e-11 |
|
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism];
Pssm-ID: 440675 [Multi-domain] Cd Length: 415 Bit Score: 66.69 E-value: 1.02e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42561620 16 FAIFWILAVFPSVPFLPIGRTAGSLFGAMLMVIFQVITPEQAYAAIDLPILgLLFGTMVVSIY-LERADMFKYLGTLLSW 94
Cdd:COG1055 223 LVLALLLVGFVLHSFLGLPPALIALLGAAVLLLLARVDVREVLKKVDWSTL-LFFIGLFVVVGgLENTGLLDLLAELLAS 301
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42561620 95 KSRGPKDL-LCRVCLVSAVSSALFTNDTSCVVLTEFVLKIARQKNlpPHPFLLALATSANIGSSATPIGNPQNLVIAVQS 173
Cdd:COG1055 302 LTGGNLLLaALLILWLSAILSAVVDNVPLVAALLPLIPDLGATGN--PEPLWLALALGATLGGNLTPIGSAANVIVLGIA 379
|
170 180 190
....*....|....*....|....*....|....*.
gi 42561620 174 K-----IPFWEFLLGVFPAMIVGITVNAMLLLGMYW 204
Cdd:COG1055 380 EkkgikISFGEFLKVGLPLTLLTLLIALLYLLLLYF 415
|
|
| ArsB_NhaD_permease |
cd00625 |
Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, ... |
5-199 |
1.22e-10 |
|
Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life. A typical anion permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a channel-forming subunit of an ATP-driven anion pump.
Pssm-ID: 238344 [Multi-domain] Cd Length: 396 Bit Score: 63.04 E-value: 1.22e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42561620 5 PVIKLVLGSVAFAIFWILAVFPSvpFLPIGRTAGSLFGAMLMVIFQVITPEQAYAAIDLPILGLLFGTMVVSIYLERADM 84
Cdd:cd00625 203 PLLKKFLLLALLLLLLFVLLFFF--LIPLGLIALLGALLLLLLLVRGLDPEEVLKSVDWGTLLFFAGLFVLVGALESTGL 280
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42561620 85 FKYLGTLLSW-KSRGPKDLLCRVCLVSAVSSALFTNDTSCVVLTEFVLKIArqknlPPHPFLLALATSANIGSSATPIGN 163
Cdd:cd00625 281 LEWLAELLVAlVGLPPLAALLLIGLLSALLSNFISNVPTVALLLPIAASLA-----PPEPAWLALALGSTLGGNLTLIGS 355
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 42561620 164 PQNLVIAVQS-----KIPFWEFLLGVFPAMIVGITVNAMLL 199
Cdd:cd00625 356 LANLIPLGAAenagvGISFGEFLKVGLPLTLLSLVVSLLYL 396
|
|
| SLC13_permease |
cd01115 |
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been ... |
1-203 |
3.95e-10 |
|
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is related to renal and intestinal Na+/sulfate cotransporters and a few putative bacterial permeases. The SLC13-type proteins belong to the ArsB/NhaD superfamily of permeases that translocate sodium and various anions across biological membranes in all three kingdoms of life. A typical ArsB/NhaD permease is composed of 8-13 transmembrane helices.
Pssm-ID: 238535 [Multi-domain] Cd Length: 382 Bit Score: 61.45 E-value: 3.95e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42561620 1 MAMAPVIKLVLGSVAFAIFWILAVFPSVPFLPIGRTAGSLFGAMLMVIFQVITPEQAYAAIDLPILGLLFGTMVVSIYLE 80
Cdd:cd01115 179 IIGLLYLWFIFRLAVLIITIVLLAALAAITGLLPVSVAIAIGAIVLVFGGVLLTKEDYKSIDWGIIFLFAGGIPLGKALE 258
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42561620 81 RADMFKYLGTLLSW--KSRGPKDLLCRVCLVSAVSSALFTNDTSCVVLTEFVLKIARQKNLPPHPFLLALATSANIgSSA 158
Cdd:cd01115 259 SSGAAALIAEALISllGGLPPFAILLLLCLLTLVLTNFISNTATAVLLAPIALSIALSLGLPPEALLLAVAIGASC-AFM 337
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 42561620 159 TPIGNPQNLVIAVQSKIPFWEFLLGVFPAMIVGITVNAMLLLGMY 203
Cdd:cd01115 338 LPVGTPPNAIVLGPGGYKFSDFAKVGLPLSILSLVVSVTMIPLIW 382
|
|
| SLC13_permease |
cd01115 |
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been ... |
332-499 |
8.57e-08 |
|
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is related to renal and intestinal Na+/sulfate cotransporters and a few putative bacterial permeases. The SLC13-type proteins belong to the ArsB/NhaD superfamily of permeases that translocate sodium and various anions across biological membranes in all three kingdoms of life. A typical ArsB/NhaD permease is composed of 8-13 transmembrane helices.
Pssm-ID: 238535 [Multi-domain] Cd Length: 382 Bit Score: 54.13 E-value: 8.57e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42561620 332 TAITAALALVVLDFKDARPSLEKVSYSLLIFFCGMFITVDGFNKTGIPTALWDLMEPYAKIDQAKGIAVLAVVILVLSNV 411
Cdd:cd01115 21 TALLVPVLLVLLGVVPPKEAFSGFSDPAVILFLAGFILGAALTRTGLAKRIATKLLKRAGKGERRLLLLLMLVTAFLSAF 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42561620 412 ASNVPTVLLLGARVAASAMGREEEKKAWLL-LAWVSTVAGNLTLLGSAANLIVCEQARRAVSHGytLTFTKHFKFGLPST 490
Cdd:cd01115 101 MSNTATVAIMLPVALGLAAKLDISPSRLLMpLAFAASIGGMLTLIGTPPNLVASGYLESLGGQG--FSFFEFTPIGLPLL 178
|
....*....
gi 42561620 491 LIVTAIGLF 499
Cdd:cd01115 179 IIGLLYLWF 187
|
|
| ArsB |
COG1055 |
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism]; |
312-502 |
2.45e-06 |
|
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism];
Pssm-ID: 440675 [Multi-domain] Cd Length: 415 Bit Score: 49.74 E-value: 2.45e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42561620 312 VYFITLGMLISLLMGLNMSWTAITAALALV---VLDFKDArpsLEKVSYSLLIFFCGMFITVDGFNKTGIPTALWDLMEP 388
Cdd:COG1055 8 IFVLTYLLIILEPRGLNRAVAALLGAALLLllgVVSLEDA---LEAIDWNTILFLLGMMIIVAILDESGFFEWLAIKLAR 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42561620 389 YAKIDQAKGIAVLAVVILVLSNVASNVPTVLLLGARVAASAMGREEEKKAWLL-LAWVSTVAGNLTLLGSAANLIVceqa 467
Cdd:COG1055 85 RAKGSPRRLLWLLGLLTALLSAFLDNDTTALLLTPVVLAIARRLGLNPVPFLIaIVFAANIGGAATPIGNPTNIMI---- 160
|
170 180 190
....*....|....*....|....*....|....*
gi 42561620 468 rrAVSHGytLTFTKHFKFGLPSTLIVTAIGLFLIK 502
Cdd:COG1055 161 --ASAGG--LSFLDFLANLFPPSLVSLLVTLLVLY 191
|
|
| CitMHS |
pfam03600 |
Citrate transporter; |
327-501 |
1.23e-05 |
|
Citrate transporter;
Pssm-ID: 460985 [Multi-domain] Cd Length: 342 Bit Score: 47.31 E-value: 1.23e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42561620 327 LNMSWTAITAALALVVLDFKDARPSLEKVSYSLLIFFCGMFITVDGFNKTGIPTALWDLMEPYAKIDQAKGIAVLAVVIL 406
Cdd:pfam03600 9 LPRDVVALLGAVLLVLLGVLTPEEALSGIDSPTILLLLGMMIIGAILERTGLFDRLALKLLRLAGGKPRRLLVALMLATA 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42561620 407 VLSNVASNVPTVLLLGA---RVAASAMGReeEKKAWLLLAWVSTVAGNLTLLGSAANLIVCEQARravshgytLTFTKHF 483
Cdd:pfam03600 89 LLSAFLSNDGTVLIMIPivlALARRLGLP--PSPLLIALAFAANIGGTATPIGDPPNIIIASALG--------LSFGDFG 158
|
170
....*....|....*...
gi 42561620 484 KFGLPSTLIVTAIGLFLI 501
Cdd:pfam03600 159 FFMFPPVGVALLLVGLLP 176
|
|
| PLN00137 |
PLN00137 |
NHAD transporter family protein; Provisional |
352-459 |
4.38e-04 |
|
NHAD transporter family protein; Provisional
Pssm-ID: 215071 Cd Length: 424 Bit Score: 42.76 E-value: 4.38e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42561620 352 LEKVSYSLLIFFCGMFITVDGFNKTGIPTALWDLMepYAKIDQAKgiaVLAVVILVLSNVASNVPTVlllgarvaASAMG 431
Cdd:PLN00137 284 LSRIDTQGILFFLGILLSVGSLDAAGILRELANYL--DANIPNVE---LIASAIGVASAIIDNVPLV--------AATMG 350
|
90 100 110
....*....|....*....|....*....|....
gi 42561620 432 REEEK------KAWLLLAWVSTVAGNLTLLGSAA 459
Cdd:PLN00137 351 MYDLTdypmdsELWQLIALCAGTGGSLLVIGSAA 384
|
|
| |
