NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|15055511|ref|NP_149441|]
View 

keratin-associated protein 3-3 [Homo sapiens]

Protein Classification

Keratin_matx domain-containing protein( domain architecture ID 10519028)

Keratin_matx domain-containing protein

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
Keratin_matx pfam04579
Keratin, high-sulphur matrix protein; Family of Keratin, high-sulfur matrix proteins. The ...
 3-96 1.67e-32

Keratin, high-sulphur matrix protein; Family of Keratin, high-sulfur matrix proteins. The keratin products of mammalian epidermal derivatives such as wool and hair consist of microfibrils embedded in a rigid matrix of other proteins. The matrix proteins include the high-sulphur and high-tyrosine keratins, having molecular weights of 6-20 kDa, whereas microfibrils contain the larger, low-sulphur keratins (40-56 kDa).


:

Pssm-ID: 461359  Cd Length: 96  Bit Score: 108.72  E-value: 1.67e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15055511    3 CCASRGCSVPTGPATTICSSDKSCRCGVCLPSTCPHTVWLLEPTCCDNCPPPCHIPQPCVPTCFLLNSCQPTPGLETLNL 82
Cdd:pfam04579  1 CCAQRCCSVPTGPATTICSSDKSCRCGVCLPSTCPHEISLLQPTCCDNCPPPCCVPDPYVPTCWLLNSCHPTPGLSGINL 80

                         90
                 ....*....|....*
gi 15055511   83 TTFTQPCCE-PCLPR 96
Cdd:pfam04579 81 TTCVQPGCEePCEPS 95
 
Name Accession Description Interval E-value
Keratin_matx pfam04579
Keratin, high-sulphur matrix protein; Family of Keratin, high-sulfur matrix proteins. The ...
 3-96 1.67e-32

Keratin, high-sulphur matrix protein; Family of Keratin, high-sulfur matrix proteins. The keratin products of mammalian epidermal derivatives such as wool and hair consist of microfibrils embedded in a rigid matrix of other proteins. The matrix proteins include the high-sulphur and high-tyrosine keratins, having molecular weights of 6-20 kDa, whereas microfibrils contain the larger, low-sulphur keratins (40-56 kDa).


Pssm-ID: 461359  Cd Length: 96  Bit Score: 108.72  E-value: 1.67e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15055511    3 CCASRGCSVPTGPATTICSSDKSCRCGVCLPSTCPHTVWLLEPTCCDNCPPPCHIPQPCVPTCFLLNSCQPTPGLETLNL 82
Cdd:pfam04579  1 CCAQRCCSVPTGPATTICSSDKSCRCGVCLPSTCPHEISLLQPTCCDNCPPPCCVPDPYVPTCWLLNSCHPTPGLSGINL 80

                         90
                 ....*....|....*
gi 15055511   83 TTFTQPCCE-PCLPR 96
Cdd:pfam04579 81 TTCVQPGCEePCEPS 95
 
Name Accession Description Interval E-value
Keratin_matx pfam04579
Keratin, high-sulphur matrix protein; Family of Keratin, high-sulfur matrix proteins. The ...
 3-96 1.67e-32

Keratin, high-sulphur matrix protein; Family of Keratin, high-sulfur matrix proteins. The keratin products of mammalian epidermal derivatives such as wool and hair consist of microfibrils embedded in a rigid matrix of other proteins. The matrix proteins include the high-sulphur and high-tyrosine keratins, having molecular weights of 6-20 kDa, whereas microfibrils contain the larger, low-sulphur keratins (40-56 kDa).


Pssm-ID: 461359  Cd Length: 96  Bit Score: 108.72  E-value: 1.67e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15055511    3 CCASRGCSVPTGPATTICSSDKSCRCGVCLPSTCPHTVWLLEPTCCDNCPPPCHIPQPCVPTCFLLNSCQPTPGLETLNL 82
Cdd:pfam04579  1 CCAQRCCSVPTGPATTICSSDKSCRCGVCLPSTCPHEISLLQPTCCDNCPPPCCVPDPYVPTCWLLNSCHPTPGLSGINL 80

                         90
                 ....*....|....*
gi 15055511   83 TTFTQPCCE-PCLPR 96
Cdd:pfam04579 81 TTCVQPGCEePCEPS 95
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH