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Conserved domains on  [gi|56790935|ref|NP_149079|]
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striatin-interacting protein 1 isoform 1 [Homo sapiens]

Protein Classification

FAR11/STRIP family protein( domain architecture ID 10546164)

FAR11/STRIP family protein containing N1221 and DUF3402 domains, similar to vertebrate striatin-interacting proteins and Schizosaccharomyces pombe factor arrest protein 11 that participates in the control of the reentry into the cell cycle following pheromone treatment

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DUF3402 pfam11882
Domain of unknown function (DUF3402); This domain is functionally uncharacterized. This domain ...
 460-783 2.35e-114

Domain of unknown function (DUF3402); This domain is functionally uncharacterized. This domain is found in eukaryotes. This presumed domain is typically between 350 to 473 amino acids in length. This domain is found associated with pfam07923.


:

Pssm-ID: 463384  Cd Length: 432  Bit Score: 355.08  E-value: 2.35e-114
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56790935   460 PRPIHESIKTLKQHKYTSIAEVQAQMEEEYLR--------------SPLSGGEEEVEQVPA---------------ETLY 510
Cdd:pfam11882   1 PASILEAGELFSKRVRMTRAMRQLWEERERFMkfergwdlddddedDDLDELTLEVDYGPRpetededvkrrldavEQFY 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56790935   511 QGLLPSLPQYM-----IALLKILLAAAPTSKAKTDSINILADVLPEEMPT-TVLQSM---------KLGVDVNRHKEVIV 575
Cdd:pfam11882  81 RDALPHLQSLVivllkIILANVTALVTQSSAANGQNINFAADELPPETGLsTPGASPrgnnnnavlIEELDVLRTREITL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56790935   576 KAISAVLLLLLKHFKLNHVYQFEYMAQHLVFANCIPLILKFF-NQNIMSYITAKN------------------------- 629
Cdd:pfam11882 161 KAVSGILLLLLKWFKLSHVLKFEYLTQLLLDSNYLPLVLKLFaNQDIQQAVTSKNdrlelsffnfcnkrsrhpppepppp 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56790935   630 --------------------------SISVLDYPHCVVHELPEltaesleagdsNQFCWRNLFSCINLLRILNKLTKWKH 683
Cdd:pfam11882 241 npeyeesseddaapppikrrrspprpEVDELGYPTNPLPEEPI-----------TDFSWRNFFSLINYLRIMQKICKNKA 309

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56790935   684 SRTMMLVVFKSAPILKRALKVKQAMMQLYVLKLLKVQTKYLGRQWRKSNMKTMSAIYQKVRHRLNDDWAYGNDLDARPWD 763
Cdd:pfam11882 310 HRNLLLVQYKSSNILKKSLKVPQPELRLYTLKLFKNQVPYCGRKWRQSNMRVITAIYLHCRPELRDDWLAGSDVDAEVEE 389

                         410       420
                  ....*....|....*....|
gi 56790935   764 FQAEECALRANIERFNARRY 783
Cdd:pfam11882 390 ALPLEQALRGLTHWYNLRRY 409
N1221 pfam07923
N1221-like protein; The sequences featured in this family are similar to a hypothetical ...
 66-336 1.90e-55

N1221-like protein; The sequences featured in this family are similar to a hypothetical protein product of ORF N1221 in the CPT1-SPC98 intergenic region of the yeast genome. This encodes an acidic polypeptide with several possible transmembrane regions.


:

Pssm-ID: 429737  Cd Length: 282  Bit Score: 192.84  E-value: 1.90e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56790935    66 PDLEFEYADTDKWAAELSELYSYTEGPEFLMNRKCFEEDFRiHVTDKKWTELDTNQHRTHAMRLLDGLEVTAREkRLKVA 145
Cdd:pfam07923   1 PAYDFEYADFDSLEEELDEWFSYSDYVLLLGAKKAFESKWS-SFCQKLWTDFDEDYRREFVEKLLEGLESNDEL-RLKAL 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56790935   146 RAILYVAQGTFGECSSEAEVQSWMRYNIFLLLEVGTFNALVELLNMEIDNSAACSSAVRKPAISLA--DSTDLRVLLNIM 223
Cdd:pfam07923  79 EALLYISLGTWGETKSSEEQLQWIKRNVKLLAECGGLPTLYEALKKAFEKCRDDIDDDDKAEEQNLqrVSTELFLLLTIL 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56790935   224 YLIVETVHQECEGDkaewrtmrQTFRAELGSPlynNEPFAIMLFGMVTKFCSGHAPHFPMKKVLLLLWKTVLCTLGGFEE 303
Cdd:pfam07923 159 YFIVEVAREEREND--------ESLRDELISL---EPPLLVFLVKYIAHLRWDSRLSMPIRKIILLLWKLLLLVFGGTSE 227

                         250       260       270
                  ....*....|....*....|....*....|...
gi 56790935   304 LQSMKAEKRsilglpPLPEDSIKVIRNMRAASP 336
Cdd:pfam07923 228 LKEVKKFLR------ELHGIKDKEKTPLLTASP 254
 
Name Accession Description Interval E-value
DUF3402 pfam11882
Domain of unknown function (DUF3402); This domain is functionally uncharacterized. This domain ...
 460-783 2.35e-114

Domain of unknown function (DUF3402); This domain is functionally uncharacterized. This domain is found in eukaryotes. This presumed domain is typically between 350 to 473 amino acids in length. This domain is found associated with pfam07923.


Pssm-ID: 463384  Cd Length: 432  Bit Score: 355.08  E-value: 2.35e-114
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56790935   460 PRPIHESIKTLKQHKYTSIAEVQAQMEEEYLR--------------SPLSGGEEEVEQVPA---------------ETLY 510
Cdd:pfam11882   1 PASILEAGELFSKRVRMTRAMRQLWEERERFMkfergwdlddddedDDLDELTLEVDYGPRpetededvkrrldavEQFY 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56790935   511 QGLLPSLPQYM-----IALLKILLAAAPTSKAKTDSINILADVLPEEMPT-TVLQSM---------KLGVDVNRHKEVIV 575
Cdd:pfam11882  81 RDALPHLQSLVivllkIILANVTALVTQSSAANGQNINFAADELPPETGLsTPGASPrgnnnnavlIEELDVLRTREITL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56790935   576 KAISAVLLLLLKHFKLNHVYQFEYMAQHLVFANCIPLILKFF-NQNIMSYITAKN------------------------- 629
Cdd:pfam11882 161 KAVSGILLLLLKWFKLSHVLKFEYLTQLLLDSNYLPLVLKLFaNQDIQQAVTSKNdrlelsffnfcnkrsrhpppepppp 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56790935   630 --------------------------SISVLDYPHCVVHELPEltaesleagdsNQFCWRNLFSCINLLRILNKLTKWKH 683
Cdd:pfam11882 241 npeyeesseddaapppikrrrspprpEVDELGYPTNPLPEEPI-----------TDFSWRNFFSLINYLRIMQKICKNKA 309

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56790935   684 SRTMMLVVFKSAPILKRALKVKQAMMQLYVLKLLKVQTKYLGRQWRKSNMKTMSAIYQKVRHRLNDDWAYGNDLDARPWD 763
Cdd:pfam11882 310 HRNLLLVQYKSSNILKKSLKVPQPELRLYTLKLFKNQVPYCGRKWRQSNMRVITAIYLHCRPELRDDWLAGSDVDAEVEE 389

                         410       420
                  ....*....|....*....|
gi 56790935   764 FQAEECALRANIERFNARRY 783
Cdd:pfam11882 390 ALPLEQALRGLTHWYNLRRY 409
N1221 pfam07923
N1221-like protein; The sequences featured in this family are similar to a hypothetical ...
 66-336 1.90e-55

N1221-like protein; The sequences featured in this family are similar to a hypothetical protein product of ORF N1221 in the CPT1-SPC98 intergenic region of the yeast genome. This encodes an acidic polypeptide with several possible transmembrane regions.


Pssm-ID: 429737  Cd Length: 282  Bit Score: 192.84  E-value: 1.90e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56790935    66 PDLEFEYADTDKWAAELSELYSYTEGPEFLMNRKCFEEDFRiHVTDKKWTELDTNQHRTHAMRLLDGLEVTAREkRLKVA 145
Cdd:pfam07923   1 PAYDFEYADFDSLEEELDEWFSYSDYVLLLGAKKAFESKWS-SFCQKLWTDFDEDYRREFVEKLLEGLESNDEL-RLKAL 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56790935   146 RAILYVAQGTFGECSSEAEVQSWMRYNIFLLLEVGTFNALVELLNMEIDNSAACSSAVRKPAISLA--DSTDLRVLLNIM 223
Cdd:pfam07923  79 EALLYISLGTWGETKSSEEQLQWIKRNVKLLAECGGLPTLYEALKKAFEKCRDDIDDDDKAEEQNLqrVSTELFLLLTIL 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56790935   224 YLIVETVHQECEGDkaewrtmrQTFRAELGSPlynNEPFAIMLFGMVTKFCSGHAPHFPMKKVLLLLWKTVLCTLGGFEE 303
Cdd:pfam07923 159 YFIVEVAREEREND--------ESLRDELISL---EPPLLVFLVKYIAHLRWDSRLSMPIRKIILLLWKLLLLVFGGTSE 227

                         250       260       270
                  ....*....|....*....|....*....|...
gi 56790935   304 LQSMKAEKRsilglpPLPEDSIKVIRNMRAASP 336
Cdd:pfam07923 228 LKEVKKFLR------ELHGIKDKEKTPLLTASP 254
 
Name Accession Description Interval E-value
DUF3402 pfam11882
Domain of unknown function (DUF3402); This domain is functionally uncharacterized. This domain ...
 460-783 2.35e-114

Domain of unknown function (DUF3402); This domain is functionally uncharacterized. This domain is found in eukaryotes. This presumed domain is typically between 350 to 473 amino acids in length. This domain is found associated with pfam07923.


Pssm-ID: 463384  Cd Length: 432  Bit Score: 355.08  E-value: 2.35e-114
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56790935   460 PRPIHESIKTLKQHKYTSIAEVQAQMEEEYLR--------------SPLSGGEEEVEQVPA---------------ETLY 510
Cdd:pfam11882   1 PASILEAGELFSKRVRMTRAMRQLWEERERFMkfergwdlddddedDDLDELTLEVDYGPRpetededvkrrldavEQFY 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56790935   511 QGLLPSLPQYM-----IALLKILLAAAPTSKAKTDSINILADVLPEEMPT-TVLQSM---------KLGVDVNRHKEVIV 575
Cdd:pfam11882  81 RDALPHLQSLVivllkIILANVTALVTQSSAANGQNINFAADELPPETGLsTPGASPrgnnnnavlIEELDVLRTREITL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56790935   576 KAISAVLLLLLKHFKLNHVYQFEYMAQHLVFANCIPLILKFF-NQNIMSYITAKN------------------------- 629
Cdd:pfam11882 161 KAVSGILLLLLKWFKLSHVLKFEYLTQLLLDSNYLPLVLKLFaNQDIQQAVTSKNdrlelsffnfcnkrsrhpppepppp 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56790935   630 --------------------------SISVLDYPHCVVHELPEltaesleagdsNQFCWRNLFSCINLLRILNKLTKWKH 683
Cdd:pfam11882 241 npeyeesseddaapppikrrrspprpEVDELGYPTNPLPEEPI-----------TDFSWRNFFSLINYLRIMQKICKNKA 309

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56790935   684 SRTMMLVVFKSAPILKRALKVKQAMMQLYVLKLLKVQTKYLGRQWRKSNMKTMSAIYQKVRHRLNDDWAYGNDLDARPWD 763
Cdd:pfam11882 310 HRNLLLVQYKSSNILKKSLKVPQPELRLYTLKLFKNQVPYCGRKWRQSNMRVITAIYLHCRPELRDDWLAGSDVDAEVEE 389

                         410       420
                  ....*....|....*....|
gi 56790935   764 FQAEECALRANIERFNARRY 783
Cdd:pfam11882 390 ALPLEQALRGLTHWYNLRRY 409
N1221 pfam07923
N1221-like protein; The sequences featured in this family are similar to a hypothetical ...
 66-336 1.90e-55

N1221-like protein; The sequences featured in this family are similar to a hypothetical protein product of ORF N1221 in the CPT1-SPC98 intergenic region of the yeast genome. This encodes an acidic polypeptide with several possible transmembrane regions.


Pssm-ID: 429737  Cd Length: 282  Bit Score: 192.84  E-value: 1.90e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56790935    66 PDLEFEYADTDKWAAELSELYSYTEGPEFLMNRKCFEEDFRiHVTDKKWTELDTNQHRTHAMRLLDGLEVTAREkRLKVA 145
Cdd:pfam07923   1 PAYDFEYADFDSLEEELDEWFSYSDYVLLLGAKKAFESKWS-SFCQKLWTDFDEDYRREFVEKLLEGLESNDEL-RLKAL 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56790935   146 RAILYVAQGTFGECSSEAEVQSWMRYNIFLLLEVGTFNALVELLNMEIDNSAACSSAVRKPAISLA--DSTDLRVLLNIM 223
Cdd:pfam07923  79 EALLYISLGTWGETKSSEEQLQWIKRNVKLLAECGGLPTLYEALKKAFEKCRDDIDDDDKAEEQNLqrVSTELFLLLTIL 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56790935   224 YLIVETVHQECEGDkaewrtmrQTFRAELGSPlynNEPFAIMLFGMVTKFCSGHAPHFPMKKVLLLLWKTVLCTLGGFEE 303
Cdd:pfam07923 159 YFIVEVAREEREND--------ESLRDELISL---EPPLLVFLVKYIAHLRWDSRLSMPIRKIILLLWKLLLLVFGGTSE 227

                         250       260       270
                  ....*....|....*....|....*....|...
gi 56790935   304 LQSMKAEKRsilglpPLPEDSIKVIRNMRAASP 336
Cdd:pfam07923 228 LKEVKKFLR------ELHGIKDKEKTPLLTASP 254
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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