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Conserved domains on  [gi|34732715|ref|NP_083957|]
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transmembrane protein 270 isoform b [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
WBS28 super family cl21030
Williams-Beuren syndrome chromosomal region 28 protein homolog; WBS28 is an integral membrane ...
1-170 1.12e-64

Williams-Beuren syndrome chromosomal region 28 protein homolog; WBS28 is an integral membrane family. These proteins have been identified as being linked to Williams-Beuren syndrome, OMIM:194050. This family of proteins is found in eukaryotes, and are typically 266 amino acids in length.


The actual alignment was detected with superfamily member pfam15164:

Pssm-ID: 464540  Cd Length: 267  Bit Score: 200.82  E-value: 1.12e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34732715     1 MEAAPRVRSGLLRILLRAGRLSALLIQNRTHLYRFLLLKMAIFQHWVLGLAQEARGSGSDQArQLPEVIITCALSLALRA 80
Cdd:pfam15164   1 MEAVPPVRSSLLGILLQVVKLSVLLVQNRVHLYNFLLLKILLFNHWVSGLAQEAQGSCSRQA-HPPPGIAACPLGRALRA 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34732715    81 GLTLLWVPMWLLLWGPRLAYRVGLCCTRTVRLALGHLCVCEPLGLSPATFRDLFLSCLHSLMLVALLLLLLTWKLMQKAH 160
Cdd:pfam15164  80 GLALLEVPVWLVLRGPRLVWAGMLGCARALGLALKRLGAWEQLGLSVATWTDLLLSCLHSLMLVALLLLLLTWRLCQKAH 159
                         170
                  ....*....|
gi 34732715   161 HFSLGWLPSQ 170
Cdd:pfam15164 160 RCSLGWLLSK 169
 
Name Accession Description Interval E-value
WBS28 pfam15164
Williams-Beuren syndrome chromosomal region 28 protein homolog; WBS28 is an integral membrane ...
1-170 1.12e-64

Williams-Beuren syndrome chromosomal region 28 protein homolog; WBS28 is an integral membrane family. These proteins have been identified as being linked to Williams-Beuren syndrome, OMIM:194050. This family of proteins is found in eukaryotes, and are typically 266 amino acids in length.


Pssm-ID: 464540  Cd Length: 267  Bit Score: 200.82  E-value: 1.12e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34732715     1 MEAAPRVRSGLLRILLRAGRLSALLIQNRTHLYRFLLLKMAIFQHWVLGLAQEARGSGSDQArQLPEVIITCALSLALRA 80
Cdd:pfam15164   1 MEAVPPVRSSLLGILLQVVKLSVLLVQNRVHLYNFLLLKILLFNHWVSGLAQEAQGSCSRQA-HPPPGIAACPLGRALRA 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34732715    81 GLTLLWVPMWLLLWGPRLAYRVGLCCTRTVRLALGHLCVCEPLGLSPATFRDLFLSCLHSLMLVALLLLLLTWKLMQKAH 160
Cdd:pfam15164  80 GLALLEVPVWLVLRGPRLVWAGMLGCARALGLALKRLGAWEQLGLSVATWTDLLLSCLHSLMLVALLLLLLTWRLCQKAH 159
                         170
                  ....*....|
gi 34732715   161 HFSLGWLPSQ 170
Cdd:pfam15164 160 RCSLGWLLSK 169
 
Name Accession Description Interval E-value
WBS28 pfam15164
Williams-Beuren syndrome chromosomal region 28 protein homolog; WBS28 is an integral membrane ...
1-170 1.12e-64

Williams-Beuren syndrome chromosomal region 28 protein homolog; WBS28 is an integral membrane family. These proteins have been identified as being linked to Williams-Beuren syndrome, OMIM:194050. This family of proteins is found in eukaryotes, and are typically 266 amino acids in length.


Pssm-ID: 464540  Cd Length: 267  Bit Score: 200.82  E-value: 1.12e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34732715     1 MEAAPRVRSGLLRILLRAGRLSALLIQNRTHLYRFLLLKMAIFQHWVLGLAQEARGSGSDQArQLPEVIITCALSLALRA 80
Cdd:pfam15164   1 MEAVPPVRSSLLGILLQVVKLSVLLVQNRVHLYNFLLLKILLFNHWVSGLAQEAQGSCSRQA-HPPPGIAACPLGRALRA 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 34732715    81 GLTLLWVPMWLLLWGPRLAYRVGLCCTRTVRLALGHLCVCEPLGLSPATFRDLFLSCLHSLMLVALLLLLLTWKLMQKAH 160
Cdd:pfam15164  80 GLALLEVPVWLVLRGPRLVWAGMLGCARALGLALKRLGAWEQLGLSVATWTDLLLSCLHSLMLVALLLLLLTWRLCQKAH 159
                         170
                  ....*....|
gi 34732715   161 HFSLGWLPSQ 170
Cdd:pfam15164 160 RCSLGWLLSK 169
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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