NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|254588116|ref|NP_082780|]
View 

clathrin heavy chain linker domain-containing protein 1 isoform 1 [Mus musculus]

Protein Classification

TSNAXIP1_N and Clathrin_H_link domain-containing protein( domain architecture ID 11239019)

TSNAXIP1_N and Clathrin_H_link domain-containing protein

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
TSNAXIP1_N pfam15739
Translin-associated factor X-interacting N-terminus; This domain is found at the N-terminus of ...
 28-152 3.01e-25

Translin-associated factor X-interacting N-terminus; This domain is found at the N-terminus of translin-associated factor X-interacting protein, a protein which may play a role in spermatogenesis.


:

Pssm-ID: 464835 [Multi-domain]  Cd Length: 111  Bit Score: 100.37  E-value: 3.01e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254588116   28 QRYITTETKRVGCKEEGPADEYYTIYRNVFDKFsatdrkiifqvIDYVSAYKSILTAIKKEYDAFIETIKKGRRTAFYLH 107
Cdd:pfam15739   1 ERKLEQELQKLGCTEDGPQELRLQVYREVFEDL-----------IEHFTTYKPLLSEIKNEYELYIAHLLESQRELQYLK 69

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 254588116  108 GKLKVLAKEPTalvyhqRRAIQLEAK---MRIIENNSTAIQLQIDQMK 152
Cdd:pfam15739  70 AKLKGLSEQSD------KRALELEEKreeIRALEKESKALLERNDKLR 111
Clathrin_H_link super family cl16430
Clathrin-H-link; This short domain is found on clathrins, and often appears on proteins ...
 308-362 3.09e-10

Clathrin-H-link; This short domain is found on clathrins, and often appears on proteins directly downstream from the Clathrin-link domain pfam09268.


The actual alignment was detected with superfamily member pfam13838:

Pssm-ID: 463995  Cd Length: 66  Bit Score: 56.06  E-value: 3.09e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 254588116  308 YIERFNDLISLGEYERAACFAANSPKRILQNTSTMNKFKAIGKIRGKPLPLLLFF 362
Cdd:pfam13838   9 YFQQFNQLLNQGDYAEAAKVAANSPRGALRTPETIQRFKQLPAQPGQLSPILQYF 63
 
Name Accession Description Interval E-value
TSNAXIP1_N pfam15739
Translin-associated factor X-interacting N-terminus; This domain is found at the N-terminus of ...
 28-152 3.01e-25

Translin-associated factor X-interacting N-terminus; This domain is found at the N-terminus of translin-associated factor X-interacting protein, a protein which may play a role in spermatogenesis.


Pssm-ID: 464835 [Multi-domain]  Cd Length: 111  Bit Score: 100.37  E-value: 3.01e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254588116   28 QRYITTETKRVGCKEEGPADEYYTIYRNVFDKFsatdrkiifqvIDYVSAYKSILTAIKKEYDAFIETIKKGRRTAFYLH 107
Cdd:pfam15739   1 ERKLEQELQKLGCTEDGPQELRLQVYREVFEDL-----------IEHFTTYKPLLSEIKNEYELYIAHLLESQRELQYLK 69

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 254588116  108 GKLKVLAKEPTalvyhqRRAIQLEAK---MRIIENNSTAIQLQIDQMK 152
Cdd:pfam15739  70 AKLKGLSEQSD------KRALELEEKreeIRALEKESKALLERNDKLR 111
Clathrin_H_link pfam13838
Clathrin-H-link; This short domain is found on clathrins, and often appears on proteins ...
 308-362 3.09e-10

Clathrin-H-link; This short domain is found on clathrins, and often appears on proteins directly downstream from the Clathrin-link domain pfam09268.


Pssm-ID: 463995  Cd Length: 66  Bit Score: 56.06  E-value: 3.09e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 254588116  308 YIERFNDLISLGEYERAACFAANSPKRILQNTSTMNKFKAIGKIRGKPLPLLLFF 362
Cdd:pfam13838   9 YFQQFNQLLNQGDYAEAAKVAANSPRGALRTPETIQRFKQLPAQPGQLSPILQYF 63
 
Name Accession Description Interval E-value
TSNAXIP1_N pfam15739
Translin-associated factor X-interacting N-terminus; This domain is found at the N-terminus of ...
 28-152 3.01e-25

Translin-associated factor X-interacting N-terminus; This domain is found at the N-terminus of translin-associated factor X-interacting protein, a protein which may play a role in spermatogenesis.


Pssm-ID: 464835 [Multi-domain]  Cd Length: 111  Bit Score: 100.37  E-value: 3.01e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254588116   28 QRYITTETKRVGCKEEGPADEYYTIYRNVFDKFsatdrkiifqvIDYVSAYKSILTAIKKEYDAFIETIKKGRRTAFYLH 107
Cdd:pfam15739   1 ERKLEQELQKLGCTEDGPQELRLQVYREVFEDL-----------IEHFTTYKPLLSEIKNEYELYIAHLLESQRELQYLK 69

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 254588116  108 GKLKVLAKEPTalvyhqRRAIQLEAK---MRIIENNSTAIQLQIDQMK 152
Cdd:pfam15739  70 AKLKGLSEQSD------KRALELEEKreeIRALEKESKALLERNDKLR 111
Clathrin_H_link pfam13838
Clathrin-H-link; This short domain is found on clathrins, and often appears on proteins ...
 308-362 3.09e-10

Clathrin-H-link; This short domain is found on clathrins, and often appears on proteins directly downstream from the Clathrin-link domain pfam09268.


Pssm-ID: 463995  Cd Length: 66  Bit Score: 56.06  E-value: 3.09e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 254588116  308 YIERFNDLISLGEYERAACFAANSPKRILQNTSTMNKFKAIGKIRGKPLPLLLFF 362
Cdd:pfam13838   9 YFQQFNQLLNQGDYAEAAKVAANSPRGALRTPETIQRFKQLPAQPGQLSPILQYF 63
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH