|
Name |
Accession |
Description |
Interval |
E-value |
| Pannexin_like |
pfam12534 |
Pannexin-like TM region of LRRC8; Pannexin_like is a family of the four transmembrane domains ... |
1-330 |
0e+00 |
|
Pannexin-like TM region of LRRC8; Pannexin_like is a family of the four transmembrane domains of metazoan leucine-rich-repeat-containing 8 proteins. These four TMs associate into hexamers resulting in homo- or heteromeric channels that connect the cytosol to the extracellular space. The family is found in association with pfam00560.
Pssm-ID: 463622 Cd Length: 345 Bit Score: 560.32 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 251823957 1 MIPVAEFKQFTEQQPAFKVLKPWWDVLAEYLTVAMLMIGVFGCTLQVTQDKIICLPSHESRENISGAPCQQLLPQGI--- 77
Cdd:pfam12534 1 MFPVTELRSFNEQQPAYRILKPWWDVFMDYLSVAMLMIAVFGGTLQLTQDKVVCLPCLESPPSTASLDDSYANSLSPtqs 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 251823957 78 -----SEQMGGLRELSGLKNNLDLQQYSFINQLCYETALHWYAKYFPYLVVIHTLIFMVCTSFWFKFPGTSSKIEHFISI 152
Cdd:pfam12534 81 aptvsSPSASMIPEPKGRKTNLDRQQYVFINQVCYEKALHWYSKYFPYLVLIHTLIFMVSSNFWFKFPGTSSKIEHFVSI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 251823957 153 LGKCFDSPWTTRALSEVSGENHKGPASGRAM------VTTVTTTGAGSGKVGEGEKEKVLIEPEKVVSE-PPVVTLLDKK 225
Cdd:pfam12534 161 LGKCFDSPWTTRALSETSGEDSEEKKQRLEGntvlpkVSSSSSLSSSDESAPLTRTPSVKSSPEKPVVEvPSTVSVLDKK 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 251823957 226 EGEQAKALFEKVKKFRVHVEEGDILYSMYIRQTVLKVCKFFAILVYNLIYVEKISFLVACRVETSEITGYASFCCNHTKA 305
Cdd:pfam12534 241 EGEQAKALFEKVKKFRAHVEESDIIYKMYVAQTVLKVLKFLLILSYTSYLVSNISFTVDCKPDIEALTGYSRFYCNHNLA 320
|
330 340
....*....|....*....|....*
gi 251823957 306 HLFSKLAFCYISFVCVYGITCLYTL 330
Cdd:pfam12534 321 FLFSKLLVFYISLVGVYGLLCLYTL 345
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
508-771 |
4.90e-36 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 141.22 E-value: 4.90e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 251823957 508 LEELHLEGLFPPEMARGATLESLRELKQLKVLSLRSNAGKVPASVTDVAGHLQRLSLHNDGARLLALNSLKKLAVLRELE 587
Cdd:COG4886 2 LLLLLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 251823957 588 LVACGLerIPHAIFSLGALQELDLKDNhlrsieeiLSFQHCRKLVTLRLWHNQIAYVPEHVRKLRSLEQLYLSHNKLETL 667
Cdd:COG4886 82 LSLLLL--GLTDLGDLTNLTELDLSGN--------EELSNLTNLESLDLSGNQLTDLPEELANLTNLKELDLSNNQLTDL 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 251823957 668 PTQLGQCFGLRLLDLSHNGLRSLPPELGLLQSLQHLALSYNALESLPDELFFCHKLRTLLLGYNHLTQLSPDVAALQALS 747
Cdd:COG4886 152 PEPLGNLTNLKSLDLSNNQLTDLPEELGNLTNLKELDLSNNQITDLPEPLGNLTNLEELDLSGNQLTDLPEPLANLTNLE 231
|
250 260
....*....|....*....|....
gi 251823957 748 RLELKGNRLETLPeELGDCKGLKK 771
Cdd:COG4886 232 TLDLSNNQLTDLP-ELGNLTNLEE 254
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
606-754 |
1.61e-16 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 79.06 E-value: 1.61e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 251823957 606 LQELDLKDNHLRSIEeilSFQHCRKLVTLRLWHNQIAYVpEHVRKLRSLEQLYLSHNKLETLpTQLGQCFGLRLLDLSHN 685
Cdd:cd21340 26 LKVLYLYDNKITKIE---NLEFLTNLTHLYLQNNQIEKI-ENLENLVNLKKLYLGGNRISVV-EGLENLTNLEELHIENQ 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 251823957 686 glrSLPPE----------LGLLQSLQHLALSYNALESLpDELFFCHKLRTLLLGYNHLT---QLSPDVAALQALSRLELK 752
Cdd:cd21340 101 ---RLPPGekltfdprslAALSNSLRVLNISGNNIDSL-EPLAPLRNLEQLDASNNQISdleELLDLLSSWPSLRELDLT 176
|
..
gi 251823957 753 GN 754
Cdd:cd21340 177 GN 178
|
|
| PRK15370 |
PRK15370 |
type III secretion system effector E3 ubiquitin transferase SlrP; |
585-763 |
3.89e-15 |
|
type III secretion system effector E3 ubiquitin transferase SlrP;
Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 79.74 E-value: 3.89e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 251823957 585 ELELVACGLERIPHAI--------------FSL-----GALQELDLKDNHLRSIEEILSfqhcRKLVTLRLWHNQIAYVP 645
Cdd:PRK15370 182 ELRLKILGLTTIPACIpeqittlildnnelKSLpenlqGNIKTLYANSNQLTSIPATLP----DTIQEMELSINRITELP 257
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 251823957 646 EHVRKlrSLEQLYLSHNKLETLPTQLGQcfGLRLLDLSHNGLRSLPPELGllQSLQHLALSYNALESLPDELffCHKLRT 725
Cdd:PRK15370 258 ERLPS--ALQSLDLFHNKISCLPENLPE--ELRYLSVYDNSIRTLPAHLP--SGITHLNVQSNSLTALPETL--PPGLKT 329
|
170 180 190
....*....|....*....|....*....|....*...
gi 251823957 726 LLLGYNHLTQLSPDVAAlqALSRLELKGNRLETLPEEL 763
Cdd:PRK15370 330 LEAGENALTSLPASLPP--ELQVLDVSKNQITVLPETL 365
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
676-733 |
2.73e-08 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 50.99 E-value: 2.73e-08
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 251823957 676 GLRLLDLSHNGLRSLPPELGL-LQSLQHLALSYNALESLPDELFFC-HKLRTLLLGYNHL 733
Cdd:pfam13855 2 NLRSLDLSNNRLTSLDDGAFKgLSNLKVLDLSNNLLTTLSPGAFSGlPSLRYLDLSGNRL 61
|
|
|
|
Name |
Accession |
Description |
Interval |
E-value |
| Pannexin_like |
pfam12534 |
Pannexin-like TM region of LRRC8; Pannexin_like is a family of the four transmembrane domains ... |
1-330 |
0e+00 |
|
Pannexin-like TM region of LRRC8; Pannexin_like is a family of the four transmembrane domains of metazoan leucine-rich-repeat-containing 8 proteins. These four TMs associate into hexamers resulting in homo- or heteromeric channels that connect the cytosol to the extracellular space. The family is found in association with pfam00560.
Pssm-ID: 463622 Cd Length: 345 Bit Score: 560.32 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 251823957 1 MIPVAEFKQFTEQQPAFKVLKPWWDVLAEYLTVAMLMIGVFGCTLQVTQDKIICLPSHESRENISGAPCQQLLPQGI--- 77
Cdd:pfam12534 1 MFPVTELRSFNEQQPAYRILKPWWDVFMDYLSVAMLMIAVFGGTLQLTQDKVVCLPCLESPPSTASLDDSYANSLSPtqs 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 251823957 78 -----SEQMGGLRELSGLKNNLDLQQYSFINQLCYETALHWYAKYFPYLVVIHTLIFMVCTSFWFKFPGTSSKIEHFISI 152
Cdd:pfam12534 81 aptvsSPSASMIPEPKGRKTNLDRQQYVFINQVCYEKALHWYSKYFPYLVLIHTLIFMVSSNFWFKFPGTSSKIEHFVSI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 251823957 153 LGKCFDSPWTTRALSEVSGENHKGPASGRAM------VTTVTTTGAGSGKVGEGEKEKVLIEPEKVVSE-PPVVTLLDKK 225
Cdd:pfam12534 161 LGKCFDSPWTTRALSETSGEDSEEKKQRLEGntvlpkVSSSSSLSSSDESAPLTRTPSVKSSPEKPVVEvPSTVSVLDKK 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 251823957 226 EGEQAKALFEKVKKFRVHVEEGDILYSMYIRQTVLKVCKFFAILVYNLIYVEKISFLVACRVETSEITGYASFCCNHTKA 305
Cdd:pfam12534 241 EGEQAKALFEKVKKFRAHVEESDIIYKMYVAQTVLKVLKFLLILSYTSYLVSNISFTVDCKPDIEALTGYSRFYCNHNLA 320
|
330 340
....*....|....*....|....*
gi 251823957 306 HLFSKLAFCYISFVCVYGITCLYTL 330
Cdd:pfam12534 321 FLFSKLLVFYISLVGVYGLLCLYTL 345
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
508-771 |
4.90e-36 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 141.22 E-value: 4.90e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 251823957 508 LEELHLEGLFPPEMARGATLESLRELKQLKVLSLRSNAGKVPASVTDVAGHLQRLSLHNDGARLLALNSLKKLAVLRELE 587
Cdd:COG4886 2 LLLLLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 251823957 588 LVACGLerIPHAIFSLGALQELDLKDNhlrsieeiLSFQHCRKLVTLRLWHNQIAYVPEHVRKLRSLEQLYLSHNKLETL 667
Cdd:COG4886 82 LSLLLL--GLTDLGDLTNLTELDLSGN--------EELSNLTNLESLDLSGNQLTDLPEELANLTNLKELDLSNNQLTDL 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 251823957 668 PTQLGQCFGLRLLDLSHNGLRSLPPELGLLQSLQHLALSYNALESLPDELFFCHKLRTLLLGYNHLTQLSPDVAALQALS 747
Cdd:COG4886 152 PEPLGNLTNLKSLDLSNNQLTDLPEELGNLTNLKELDLSNNQITDLPEPLGNLTNLEELDLSGNQLTDLPEPLANLTNLE 231
|
250 260
....*....|....*....|....
gi 251823957 748 RLELKGNRLETLPeELGDCKGLKK 771
Cdd:COG4886 232 TLDLSNNQLTDLP-ELGNLTNLEE 254
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
350-720 |
7.50e-19 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 89.99 E-value: 7.50e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 251823957 350 TGMNDIPDVKNDFAFMLHLIDQYDSLYSKRFAVFLSEVSESRLKQLNLNHEWTPEKLRQKLQRNMRGRLELSLCMLPGLP 429
Cdd:COG4886 10 LKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGL 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 251823957 430 DTVFELSEVEALrleaicDISFPPGLSQLVNLQELSLLHSparlpfssqiflrdrlkvicvkfeELREVPLWVFGLRGLE 509
Cdd:COG4886 90 TDLGDLTNLTEL------DLSGNEELSNLTNLESLDLSGN------------------------QLTDLPEELANLTNLK 139
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 251823957 510 ELHLEG----LFPpemargatlESLRELKQLKVLSLRSNA-GKVPASVTDVAgHLQRLSLHNDgaRLLAL-NSLKKLAVL 583
Cdd:COG4886 140 ELDLSNnqltDLP---------EPLGNLTNLKSLDLSNNQlTDLPEELGNLT-NLKELDLSNN--QITDLpEPLGNLTNL 207
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 251823957 584 RELELVACGLERIPHAIFSLGALQELDLKDNHLRSIEEILSFQhcrKLVTLRLWHNQIAYVPEhVRKLRSLEQLYLSHNK 663
Cdd:COG4886 208 EELDLSGNQLTDLPEPLANLTNLETLDLSNNQLTDLPELGNLT---NLEELDLSNNQLTDLPP-LANLTNLKTLDLSNNQ 283
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*...
gi 251823957 664 LETLP-TQLGQCFGLRLLDLSHNGLRSLPPELGLLQSLQHLALSYNALESLPDELFFC 720
Cdd:COG4886 284 LTDLKlKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLA 341
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
606-754 |
1.61e-16 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 79.06 E-value: 1.61e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 251823957 606 LQELDLKDNHLRSIEeilSFQHCRKLVTLRLWHNQIAYVpEHVRKLRSLEQLYLSHNKLETLpTQLGQCFGLRLLDLSHN 685
Cdd:cd21340 26 LKVLYLYDNKITKIE---NLEFLTNLTHLYLQNNQIEKI-ENLENLVNLKKLYLGGNRISVV-EGLENLTNLEELHIENQ 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 251823957 686 glrSLPPE----------LGLLQSLQHLALSYNALESLpDELFFCHKLRTLLLGYNHLT---QLSPDVAALQALSRLELK 752
Cdd:cd21340 101 ---RLPPGekltfdprslAALSNSLRVLNISGNNIDSL-EPLAPLRNLEQLDASNNQISdleELLDLLSSWPSLRELDLT 176
|
..
gi 251823957 753 GN 754
Cdd:cd21340 177 GN 178
|
|
| PRK15370 |
PRK15370 |
type III secretion system effector E3 ubiquitin transferase SlrP; |
585-763 |
3.89e-15 |
|
type III secretion system effector E3 ubiquitin transferase SlrP;
Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 79.74 E-value: 3.89e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 251823957 585 ELELVACGLERIPHAI--------------FSL-----GALQELDLKDNHLRSIEEILSfqhcRKLVTLRLWHNQIAYVP 645
Cdd:PRK15370 182 ELRLKILGLTTIPACIpeqittlildnnelKSLpenlqGNIKTLYANSNQLTSIPATLP----DTIQEMELSINRITELP 257
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 251823957 646 EHVRKlrSLEQLYLSHNKLETLPTQLGQcfGLRLLDLSHNGLRSLPPELGllQSLQHLALSYNALESLPDELffCHKLRT 725
Cdd:PRK15370 258 ERLPS--ALQSLDLFHNKISCLPENLPE--ELRYLSVYDNSIRTLPAHLP--SGITHLNVQSNSLTALPETL--PPGLKT 329
|
170 180 190
....*....|....*....|....*....|....*...
gi 251823957 726 LLLGYNHLTQLSPDVAAlqALSRLELKGNRLETLPEEL 763
Cdd:PRK15370 330 LEAGENALTSLPASLPP--ELQVLDVSKNQITVLPETL 365
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
450-769 |
2.12e-14 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 77.58 E-value: 2.12e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 251823957 450 SFPPGLSQLVNLQELSLLHSPARLPFSSQIFlrDRLKVICVKFEELR---EVPLWVFGLRGLEELHLeglFPPEMArGAT 526
Cdd:PLN00113 251 PIPSSLGNLKNLQYLFLYQNKLSGPIPPSIF--SLQKLISLDLSDNSlsgEIPELVIQLQNLEILHL---FSNNFT-GKI 324
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 251823957 527 LESLRELKQLKVLSLRSN--AGKVPASvtdvaghlqrLSLHNDGARL-LALNSLKKlavlrelelvacgleRIPHAIFSL 603
Cdd:PLN00113 325 PVALTSLPRLQVLQLWSNkfSGEIPKN----------LGKHNNLTVLdLSTNNLTG---------------EIPEGLCSS 379
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 251823957 604 GALQELDLKDNHLRSiEEILSFQHCRKLVTLRLWHNQIA-YVPEHVRKLRSLEQLYLSHNKLE--------TLPT----- 669
Cdd:PLN00113 380 GNLFKLILFSNSLEG-EIPKSLGACRSLRRVRLQDNSFSgELPSEFTKLPLVYFLDISNNNLQgrinsrkwDMPSlqmls 458
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 251823957 670 --------QLGQCFG---LRLLDLSHNGLR-SLPPELGLLQSLQHLALSYNALES-LPDELFFCHKLRTLLLGYNHLT-Q 735
Cdd:PLN00113 459 larnkffgGLPDSFGskrLENLDLSRNQFSgAVPRKLGSLSELMQLKLSENKLSGeIPDELSSCKKLVSLDLSHNQLSgQ 538
|
330 340 350
....*....|....*....|....*....|....*
gi 251823957 736 LSPDVAALQALSRLELKGNRLE-TLPEELGDCKGL 769
Cdd:PLN00113 539 IPASFSEMPVLSQLDLSQNQLSgEIPKNLGNVESL 573
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
412-756 |
2.79e-11 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 67.18 E-value: 2.79e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 251823957 412 RNMRGRLELSLCMLP--------------GLPDTVFELSEveALRLEAICDISFPPGLSQ--LVNLQELSLLHSPARLPF 475
Cdd:PLN00113 79 KNISGKISSAIFRLPyiqtinlsnnqlsgPIPDDIFTTSS--SLRYLNLSNNNFTGSIPRgsIPNLETLDLSNNMLSGEI 156
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 251823957 476 SSQIFLRDRLKVICVKFEELR-EVPLWVFGLRGLEEL-----HLEGLFPPEMARgatleslreLKQLKVLSLRSN--AGK 547
Cdd:PLN00113 157 PNDIGSFSSLKVLDLGGNVLVgKIPNSLTNLTSLEFLtlasnQLVGQIPRELGQ---------MKSLKWIYLGYNnlSGE 227
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 251823957 548 VPASVTDVAG--HLQRLSLHNDGARLLALNSLKKLAVLRELELVACGleRIPHAIFSLGALQELDLKDNHLR-SIEEILS 624
Cdd:PLN00113 228 IPYEIGGLTSlnHLDLVYNNLTGPIPSSLGNLKNLQYLFLYQNKLSG--PIPPSIFSLQKLISLDLSDNSLSgEIPELVI 305
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 251823957 625 fqHCRKLVTLRLWHNQI-AYVPEHVRKLRSLEQLYLSHNKLE-TLPTQLGQCFGLRLLDLSHNGLRSLPPElGLLQS--L 700
Cdd:PLN00113 306 --QLQNLEILHLFSNNFtGKIPVALTSLPRLQVLQLWSNKFSgEIPKNLGKHNNLTVLDLSTNNLTGEIPE-GLCSSgnL 382
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*...
gi 251823957 701 QHLALSYNALES-LPDELFFCHKLRTLLLGYNHLT-QLSPDVAALQALSRLELKGNRL 756
Cdd:PLN00113 383 FKLILFSNSLEGeIPKSLGACRSLRRVRLQDNSFSgELPSEFTKLPLVYFLDISNNNL 440
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
536-771 |
2.57e-09 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 61.02 E-value: 2.57e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 251823957 536 LKVLSLRSNA--GKVPASVTDVAGhLQRLSLhndgarllALNSL-----KKLAVLRELELVACGLE----RIPHAIFSLG 604
Cdd:PLN00113 166 LKVLDLGGNVlvGKIPNSLTNLTS-LEFLTL--------ASNQLvgqipRELGQMKSLKWIYLGYNnlsgEIPYEIGGLT 236
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 251823957 605 ALQELDLKDNHLrsIEEI-LSFQHCRKLVTLRLWHNQIA-YVPEHVRKLRSLEQLYLSHNKLE-TLPTQLGQCFGLRLLD 681
Cdd:PLN00113 237 SLNHLDLVYNNL--TGPIpSSLGNLKNLQYLFLYQNKLSgPIPPSIFSLQKLISLDLSDNSLSgEIPELVIQLQNLEILH 314
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 251823957 682 LSHNGLR-SLPPELGLLQSLQHLALSYNALE-SLPDELFFCHKLRTLLLGYNHLTQLSPD-VAALQALSRLELKGNRLET 758
Cdd:PLN00113 315 LFSNNFTgKIPVALTSLPRLQVLQLWSNKFSgEIPKNLGKHNNLTVLDLSTNNLTGEIPEgLCSSGNLFKLILFSNSLEG 394
|
250
....*....|....
gi 251823957 759 -LPEELGDCKGLKK 771
Cdd:PLN00113 395 eIPKSLGACRSLRR 408
|
|
| PRK15370 |
PRK15370 |
type III secretion system effector E3 ubiquitin transferase SlrP; |
630-789 |
2.83e-09 |
|
type III secretion system effector E3 ubiquitin transferase SlrP;
Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 60.87 E-value: 2.83e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 251823957 630 KLVTLRLWHNQIAYVPEHVRKlrSLEQLYLSHNKLETLPTQLGQCfgLRLLDLSHNGLRSLPPELGllQSLQHLALSYNA 709
Cdd:PRK15370 200 QITTLILDNNELKSLPENLQG--NIKTLYANSNQLTSIPATLPDT--IQEMELSINRITELPERLP--SALQSLDLFHNK 273
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 251823957 710 LESLPDELffCHKLRTLLLGYNHLTQLSPDVAAlqALSRLELKGNRLETLPEELGdcKGLKksgLLVED-----TLYEGL 784
Cdd:PRK15370 274 ISCLPENL--PEELRYLSVYDNSIRTLPAHLPS--GITHLNVQSNSLTALPETLP--PGLK---TLEAGenaltSLPASL 344
|
....*
gi 251823957 785 PAEVR 789
Cdd:PRK15370 345 PPELQ 349
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
479-756 |
6.07e-09 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 59.03 E-value: 6.07e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 251823957 479 IFLRDRLKVICVKFEELREVPLWvfglrglEELHLEGLFPPEMAR--GATLESLRELKQLKVLSLRSNAGKVPASVTDVa 556
Cdd:COG5238 84 AFPTQLLVVDWEGAEEVSPVALA-------ETATAVATPPPDLRRimAKTLEDSLILYLALPRRINLIQVLKDPLGGNA- 155
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 251823957 557 ghlQRLSLHNDGARLLALNSLKKLAVLRELELVAC--------GLERIPHAIFSLGALQELDLKDNHL--RSIEEILS-F 625
Cdd:COG5238 156 ---VHLLGLAARLGLLAAISMAKALQNNSVETVYLgcnqigdeGIEELAEALTQNTTVTTLWLKRNPIgdEGAEILAEaL 232
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 251823957 626 QHCRKLVTLRLWHNQI-----AYVPEHVRKLRSLEQLYLSHNKL-----ETLPTQLGQCFGLRLLDLSHNGLRSlPPELG 695
Cdd:COG5238 233 KGNKSLTTLDLSNNQIgdegvIALAEALKNNTTVETLYLSGNQIgaegaIALAKALQGNTTLTSLDLSVNRIGD-EGAIA 311
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 251823957 696 LLQSLQHlalsynaleslpdelffCHKLRTLLLGYNhltQLSPD-----VAALQA---LSRLELKGNRL 756
Cdd:COG5238 312 LAEGLQG-----------------NKTLHTLNLAYN---GIGAQgaialAKALQEnttLHSLDLSDNQI 360
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
676-733 |
2.73e-08 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 50.99 E-value: 2.73e-08
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 251823957 676 GLRLLDLSHNGLRSLPPELGL-LQSLQHLALSYNALESLPDELFFC-HKLRTLLLGYNHL 733
Cdd:pfam13855 2 NLRSLDLSNNRLTSLDDGAFKgLSNLKVLDLSNNLLTTLSPGAFSGlPSLRYLDLSGNRL 61
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
596-692 |
2.18e-07 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 54.85 E-value: 2.18e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 251823957 596 IPHAIFSLGALQELDLKDNHLRS-IEEILSfqHCRKLVTLRLWHNQIA-YVPEHVRKLRSLEQLYLSHNKLE-TLPTQLG 672
Cdd:PLN00113 491 VPRKLGSLSELMQLKLSENKLSGeIPDELS--SCKKLVSLDLSHNQLSgQIPASFSEMPVLSQLDLSQNQLSgEIPKNLG 568
|
90 100
....*....|....*....|.
gi 251823957 673 QCFGLRLLDLSHNGLR-SLPP 692
Cdd:PLN00113 569 NVESLVQVNISHNHLHgSLPS 589
|
|
| PLN03150 |
PLN03150 |
hypothetical protein; Provisional |
643-710 |
2.65e-07 |
|
hypothetical protein; Provisional
Pssm-ID: 178695 [Multi-domain] Cd Length: 623 Bit Score: 54.05 E-value: 2.65e-07
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 251823957 643 YVPEHVRKLRSLEQLYLSHNKLE-TLPTQLGQCFGLRLLDLSHNGLR-SLPPELGLLQSLQHLALSYNAL 710
Cdd:PLN03150 433 FIPNDISKLRHLQSINLSGNSIRgNIPPSLGSITSLEVLDLSYNSFNgSIPESLGQLTSLRILNLNGNSL 502
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
698-756 |
1.22e-06 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 46.36 E-value: 1.22e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 251823957 698 QSLQHLALSYNALESLPDELFF-CHKLRTLLLGYNHLTQLSPDV-AALQALSRLELKGNRL 756
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKgLSNLKVLDLSNNLLTTLSPGAfSGLPSLRYLDLSGNRL 61
|
|
| PRK15370 |
PRK15370 |
type III secretion system effector E3 ubiquitin transferase SlrP; |
527-717 |
1.64e-06 |
|
type III secretion system effector E3 ubiquitin transferase SlrP;
Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 51.62 E-value: 1.64e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 251823957 527 LESLRELKQ--LKVLSLRSNA-GKVPASVTDVAGHLQrlslhndgarlLALNSLKKL-----AVLRELELVACGLERIPH 598
Cdd:PRK15370 211 LKSLPENLQgnIKTLYANSNQlTSIPATLPDTIQEME-----------LSINRITELperlpSALQSLDLFHNKISCLPE 279
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 251823957 599 AIFSlgALQELDLKDNHLRSIEEILSfqhcRKLVTLRLWHNQIAYVPEHV-RKLRSLEQ------------------LYL 659
Cdd:PRK15370 280 NLPE--ELRYLSVYDNSIRTLPAHLP----SGITHLNVQSNSLTALPETLpPGLKTLEAgenaltslpaslppelqvLDV 353
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 251823957 660 SHNKLETLPTQLGQCfgLRLLDLSHNGLRSLPPELGllQSLQHLALSYNALESLPDEL 717
Cdd:PRK15370 354 SKNQITVLPETLPPT--ITTLDVSRNALTNLPENLP--AALQIMQASRNNLVRLPESL 407
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
629-687 |
1.67e-06 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 45.98 E-value: 1.67e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 251823957 629 RKLVTLRLWHNQIAYVPEHV-RKLRSLEQLYLSHNKLETLPTQLGQCF-GLRLLDLSHNGL 687
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAfKGLSNLKVLDLSNNLLTTLSPGAFSGLpSLRYLDLSGNRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
583-641 |
1.92e-05 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 42.90 E-value: 1.92e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 251823957 583 LRELELVACGLERI-PHAIFSLGALQELDLKDNHLRSIEEIlSFQHCRKLVTLRLWHNQI 641
Cdd:pfam13855 3 LRSLDLSNNRLTSLdDGAFKGLSNLKVLDLSNNLLTTLSPG-AFSGLPSLRYLDLSGNRL 61
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
526-790 |
8.77e-05 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 45.42 E-value: 8.77e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 251823957 526 TLESLRELKQLKVLSLRSNagkvpaSVTDVAGHLQRLSLHNDGARLLALNSLKKLA-VLRELELVACGLERIPhaifslg 604
Cdd:cd00116 15 ATELLPKLLCLQVLRLEGN------TLGEEAAKALASALRPQPSLKELCLSLNETGrIPRGLQSLLQGLTKGC------- 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 251823957 605 ALQELDLKDNHLrSIEEILSFQHCRKLVTLRLWH-NQIAYVPEHVRKL--------RSLEQLYLSHNKLE-TLPTQLGQC 674
Cdd:cd00116 82 GLQELDLSDNAL-GPDGCGVLESLLRSSSLQELKlNNNGLGDRGLRLLakglkdlpPALEKLVLGRNRLEgASCEALAKA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 251823957 675 F----GLRLLDLSHN-----GLRSLPPELGLLQSLQHLALSYNALESLPDElFFCH------KLRTLLLGYNHLTqlSPD 739
Cdd:cd00116 161 LranrDLKELNLANNgigdaGIRALAEGLKANCNLEVLDLNNNGLTDEGAS-ALAEtlaslkSLEVLNLGDNNLT--DAG 237
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 251823957 740 VAAL--------QALSRLELKGNRLE-----TLPEELGDCKGLKKSGLLVEDTLYEG--LPAEVRE 790
Cdd:cd00116 238 AAALasallspnISLLTLSLSCNDITddgakDLAEVLAEKESLLELDLRGNKFGEEGaqLLAESLL 303
|
|
| PRK15387 |
PRK15387 |
type III secretion system effector E3 ubiquitin transferase SspH2; |
583-773 |
4.09e-04 |
|
type III secretion system effector E3 ubiquitin transferase SspH2;
Pssm-ID: 185285 [Multi-domain] Cd Length: 788 Bit Score: 44.00 E-value: 4.09e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 251823957 583 LRELELVACGLERIPhaIFSLGALqELDLKDNHLRSIEEILSfqhcrKLVTLRLWHNQIAYVPEHVRklrSLEQLYLSHN 662
Cdd:PRK15387 244 LRTLEVSGNQLTSLP--VLPPGLL-ELSIFSNPLTHLPALPS-----GLCKLWIFGNQLTSLPVLPP---GLQELSVSDN 312
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 251823957 663 KLETLPTQLGQcfgLRLLDLSHNGLRSLPPelgLLQSLQHLALSYNALESLPDelfFCHKLRTLLLGYNHLTQLSpdvAA 742
Cdd:PRK15387 313 QLASLPALPSE---LCKLWAYNNQLTSLPT---LPSGLQELSVSDNQLASLPT---LPSELYKLWAYNNRLTSLP---AL 380
|
170 180 190
....*....|....*....|....*....|.
gi 251823957 743 LQALSRLELKGNRLETLPEELGDCKGLKKSG 773
Cdd:PRK15387 381 PSGLKELIVSGNRLTSLPVLPSELKELMVSG 411
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
527-667 |
5.66e-04 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 42.08 E-value: 5.66e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 251823957 527 LESLRELKQLKVLSLRSNagkvpaSVTDVAGhLQRLS----LHNDGARL-----LALN--SLKKLAV-LRELELVACGLE 594
Cdd:cd21340 61 IENLENLVNLKKLYLGGN------RISVVEG-LENLTnleeLHIENQRLppgekLTFDprSLAALSNsLRVLNISGNNID 133
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 251823957 595 RIpHAIFSLGALQELDLKDNHLRSIEEIL-SFQHCRKLVTLRLWHNQIAyvpeHVRKLRslEQLYLSHNKLETL 667
Cdd:cd21340 134 SL-EPLAPLRNLEQLDASNNQISDLEELLdLLSSWPSLRELDLTGNPVC----KKPKYR--DKIILASKSLEVL 200
|
|
| PRK15387 |
PRK15387 |
type III secretion system effector E3 ubiquitin transferase SspH2; |
631-760 |
1.56e-03 |
|
type III secretion system effector E3 ubiquitin transferase SspH2;
Pssm-ID: 185285 [Multi-domain] Cd Length: 788 Bit Score: 42.07 E-value: 1.56e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 251823957 631 LVTLRLWHNQIAYVPEHVRKLRsleQLYLSHNKLETLPTQLGqcfGLRLLDLSHNGLRSLPPelgLLQSLQHLALSYNAL 710
Cdd:PRK15387 304 LQELSVSDNQLASLPALPSELC---KLWAYNNQLTSLPTLPS---GLQELSVSDNQLASLPT---LPSELYKLWAYNNRL 374
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 251823957 711 ESLPDelfFCHKLRTLLLGYNHLTQLsPDVAAlqALSRLELKGNRLETLP 760
Cdd:PRK15387 375 TSLPA---LPSGLKELIVSGNRLTSL-PVLPS--ELKELMVSGNRLTSLP 418
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
532-669 |
3.24e-03 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 40.99 E-value: 3.24e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 251823957 532 ELKQLKVLSLRSNA--GKVPASVTdvAGHLQRLSLHNDGARLLALNSLKKLAVLRELELVACGLE-RIPHAIFSLGALQE 608
Cdd:PLN00113 450 DMPSLQMLSLARNKffGGLPDSFG--SKRLENLDLSRNQFSGAVPRKLGSLSELMQLKLSENKLSgEIPDELSSCKKLVS 527
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 251823957 609 LDLKDNHLrSIEEILSFQHCRKLVTLRLWHNQIA-YVPEHVRKLRSLEQLYLSHNKLE-TLPT 669
Cdd:PLN00113 528 LDLSHNQL-SGQIPASFSEMPVLSQLDLSQNQLSgEIPKNLGNVESLVQVNISHNHLHgSLPS 589
|
|
| PLN03210 |
PLN03210 |
Resistant to P. syringae 6; Provisional |
583-760 |
7.58e-03 |
|
Resistant to P. syringae 6; Provisional
Pssm-ID: 215633 [Multi-domain] Cd Length: 1153 Bit Score: 39.86 E-value: 7.58e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 251823957 583 LRELELVACGLERIPHAIFSLGALQELDLKDNhlRSIEEILSFQHCRKLVTLRLWH-NQIAYVPEHVRKLRSLEQLYLSH 661
Cdd:PLN03210 613 LVKLQMQGSKLEKLWDGVHSLTGLRNIDLRGS--KNLKEIPDLSMATNLETLKLSDcSSLVELPSSIQYLNKLEDLDMSR 690
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 251823957 662 -NKLETLPT----------QLGQCFGLRL----------LDLSHNGLRSLPPELGlLQSLQHLALSYNALESLPDEL--- 717
Cdd:PLN03210 691 cENLEILPTginlkslyrlNLSGCSRLKSfpdistniswLDLDETAIEEFPSNLR-LENLDELILCEMKSEKLWERVqpl 769
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 251823957 718 -----FFCHKLRTLLLGYN-HLTQLSPDVAALQALSRLELKGNR-LETLP 760
Cdd:PLN03210 770 tplmtMLSPSLTRLFLSDIpSLVELPSSIQNLHKLEHLEIENCInLETLP 819
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
525-685 |
9.74e-03 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 38.88 E-value: 9.74e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 251823957 525 ATLESLRELKQLKVLSLRSNagkvpasvtdvaghlqrlSLHNDGARLLALnSLKKLAVLRELELVACGLER-----IPHA 599
Cdd:cd00116 156 ALAKALRANRDLKELNLANN------------------GIGDAGIRALAE-GLKANCNLEVLDLNNNGLTDegasaLAET 216
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 251823957 600 IFSLGALQELDLKDNHLRS--IEEILS--FQHCRKLVTLRLWHNQIAY-----VPEHVRKLRSLEQLYLSHNKL----ET 666
Cdd:cd00116 217 LASLKSLEVLNLGDNNLTDagAAALASalLSPNISLLTLSLSCNDITDdgakdLAEVLAEKESLLELDLRGNKFgeegAQ 296
|
170 180
....*....|....*....|.
gi 251823957 667 LPTQLGQCFG--LRLLDLSHN 685
Cdd:cd00116 297 LLAESLLEPGneLESLWVKDD 317
|
|
|