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Concise Results
Standard Results
Full Results
heat shock protein 75 kDa, mitochondrial precursor [Mus musculus]
Protein Classification
Hsp90 family chaperone protein ( domain architecture ID 11480452 )
Hsp90 (heat shock protein 90) family chaperone protein, such as molecular chaperone HtpG (high-temperature protein G) that facilitates the folding and conformational changes of a wide array of proteins
List of domain hits
Name
Accession
Description
Interval
E-value
PRK05218
PRK05218 heat shock protein 90; Provisional
89-704
0e+00
heat shock protein 90; Provisional
Pssm-ID: 235366 [Multi-domain]
Cd Length: 613
Bit Score: 699.17
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13385998 89 KH EFQAE T K K LL DIVAR SLYS E KE V F I RELISNASDA LE KLR HKLVCEGQVL --- PEME I HLQT D AKKG T I TI Q D T GIGM 165
Cdd:PRK05218 5 TG EFQAE V K Q LL HLMIH SLYS N KE I F L RELISNASDA ID KLR FEALTDPALY egd GDLK I RISF D KEAR T L TI S D N GIGM 84
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13385998 166 T Q EE LVS NLGTIA R SG S K A FLE A L QNQAETS S KI IGQFGVGFYSAFMVADKV E V YS RSA A P ESPGYQ W L SDG S G VFE I A E 245
Cdd:PRK05218 85 T R EE VIE NLGTIA K SG T K E FLE K L KGDQKKD S QL IGQFGVGFYSAFMVADKV T V IT RSA G P AAEAVR W E SDG E G EYT I E E 164
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13385998 246 ASGVRP GT K I II HLK S D CKD F AS E S R VQDVVT KYS N F VSF P LY L NGK --- R IN TLQ A I W MMDPKD I SEFQHE EFY RYI A Q 322
Cdd:PRK05218 165 IEKEER GT E I TL HLK E D EDE F LD E W R IRSIIK KYS D F IPV P IK L EKE eee T IN SAS A L W TRSKSE I TDEEYK EFY KHL A H 244
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13385998 323 AY D K P R F TL H YKTDA P LNIRSIF Y V P EMK P sm FD V - S R ELGSSVA LY SRK V L I QTK A ADI LP KW LRF IR GV V DSED I PLN 401
Cdd:PRK05218 245 DF D D P L F WI H NNVEG P FEYTGLL Y I P KKA P -- FD L f N R DRKGGLK LY VKR V F I MDD A EEL LP EY LRF VK GV I DSED L PLN 322
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13385998 402 L SRE L LQE SALIR K L R DVLQQRLIKFFIDQS K K D A EKY A KF FEDY G LFMR EG IVTTAEQ di K E DI AKLLR YE S SA lp A G Q 481
Cdd:PRK05218 323 V SRE I LQE DRVVK K I R KAITKKVLDELEKLA K N D R EKY E KF WKEF G PVLK EG LYEDFAN -- R E KL AKLLR FA S TH -- E G K 398
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13385998 482 LT SL PD Y AS RM QA G TRN IYY LCAPN R HL A EH SP YY E AM K Q K HT EVL FCYEQF DE LTLLH L R EFD K K KLI SV e TDIVV D HY 561
Cdd:PRK05218 399 YV SL AE Y VE RM KE G QKK IYY ITGDS R EA A KN SP HL E LF K K K GI EVL LLTDPI DE FWISY L E EFD G K PFK SV - ARGDL D LG 477
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13385998 562 KE EKF E DTSPADE rls E K E TED L MAWMRN ALG SR V TN V KVTF RL DTH PA MVTVL E MG aarhfl RMQ Q LA K TQEERA Q LL - 640
Cdd:PRK05218 478 KE DEE E KEEKEEA --- E E E FKP L LERLKE ALG DK V KD V RLSH RL TDS PA CLVAD E GD ------ MST Q ME K LLKAAG Q EV p 548
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 13385998 641 -- Q P T LEINP R H T L I KKL cq LR E SEPELAQL L VDQI Y EN A MI A A G L - VD DP R A M V G RLN D LL V K V L E 704
Cdd:PRK05218 549 es K P I LEINP N H P L V KKL -- AD E ADEAKFKD L AELL Y DQ A LL A E G G s LE DP A A F V K RLN E LL L K L L A 613
Name
Accession
Description
Interval
E-value
PRK05218
PRK05218 heat shock protein 90; Provisional
89-704
0e+00
heat shock protein 90; Provisional
Pssm-ID: 235366 [Multi-domain]
Cd Length: 613
Bit Score: 699.17
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13385998 89 KH EFQAE T K K LL DIVAR SLYS E KE V F I RELISNASDA LE KLR HKLVCEGQVL --- PEME I HLQT D AKKG T I TI Q D T GIGM 165
Cdd:PRK05218 5 TG EFQAE V K Q LL HLMIH SLYS N KE I F L RELISNASDA ID KLR FEALTDPALY egd GDLK I RISF D KEAR T L TI S D N GIGM 84
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13385998 166 T Q EE LVS NLGTIA R SG S K A FLE A L QNQAETS S KI IGQFGVGFYSAFMVADKV E V YS RSA A P ESPGYQ W L SDG S G VFE I A E 245
Cdd:PRK05218 85 T R EE VIE NLGTIA K SG T K E FLE K L KGDQKKD S QL IGQFGVGFYSAFMVADKV T V IT RSA G P AAEAVR W E SDG E G EYT I E E 164
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13385998 246 ASGVRP GT K I II HLK S D CKD F AS E S R VQDVVT KYS N F VSF P LY L NGK --- R IN TLQ A I W MMDPKD I SEFQHE EFY RYI A Q 322
Cdd:PRK05218 165 IEKEER GT E I TL HLK E D EDE F LD E W R IRSIIK KYS D F IPV P IK L EKE eee T IN SAS A L W TRSKSE I TDEEYK EFY KHL A H 244
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13385998 323 AY D K P R F TL H YKTDA P LNIRSIF Y V P EMK P sm FD V - S R ELGSSVA LY SRK V L I QTK A ADI LP KW LRF IR GV V DSED I PLN 401
Cdd:PRK05218 245 DF D D P L F WI H NNVEG P FEYTGLL Y I P KKA P -- FD L f N R DRKGGLK LY VKR V F I MDD A EEL LP EY LRF VK GV I DSED L PLN 322
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13385998 402 L SRE L LQE SALIR K L R DVLQQRLIKFFIDQS K K D A EKY A KF FEDY G LFMR EG IVTTAEQ di K E DI AKLLR YE S SA lp A G Q 481
Cdd:PRK05218 323 V SRE I LQE DRVVK K I R KAITKKVLDELEKLA K N D R EKY E KF WKEF G PVLK EG LYEDFAN -- R E KL AKLLR FA S TH -- E G K 398
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13385998 482 LT SL PD Y AS RM QA G TRN IYY LCAPN R HL A EH SP YY E AM K Q K HT EVL FCYEQF DE LTLLH L R EFD K K KLI SV e TDIVV D HY 561
Cdd:PRK05218 399 YV SL AE Y VE RM KE G QKK IYY ITGDS R EA A KN SP HL E LF K K K GI EVL LLTDPI DE FWISY L E EFD G K PFK SV - ARGDL D LG 477
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13385998 562 KE EKF E DTSPADE rls E K E TED L MAWMRN ALG SR V TN V KVTF RL DTH PA MVTVL E MG aarhfl RMQ Q LA K TQEERA Q LL - 640
Cdd:PRK05218 478 KE DEE E KEEKEEA --- E E E FKP L LERLKE ALG DK V KD V RLSH RL TDS PA CLVAD E GD ------ MST Q ME K LLKAAG Q EV p 548
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 13385998 641 -- Q P T LEINP R H T L I KKL cq LR E SEPELAQL L VDQI Y EN A MI A A G L - VD DP R A M V G RLN D LL V K V L E 704
Cdd:PRK05218 549 es K P I LEINP N H P L V KKL -- AD E ADEAKFKD L AELL Y DQ A LL A E G G s LE DP A A F V K RLN E LL L K L L A 613
HtpG
COG0326 Molecular chaperone, HSP90 family [Posttranslational modification, protein turnover, ...
89-704
0e+00
Molecular chaperone, HSP90 family [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440095 [Multi-domain]
Cd Length: 616
Bit Score: 691.86
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13385998 89 KH EFQAE T K K LLD IVAR SLYS E KE V F I RELISNASDA LE KLR HKLVCEGQVL --- PEME I HLQT D AKKG T I TI Q D T GIGM 165
Cdd:COG0326 5 TG EFQAE V K Q LLD LMIH SLYS N KE I F L RELISNASDA ID KLR FLALTDPELK eed GDLK I RIEV D KEAK T L TI S D N GIGM 84
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13385998 166 T Q EE LVS NLGTIA R SG SKA FLE A L QNQAETS S KI IGQFGVGFYSAFMVADKVEV YS RSA APESPGYQ W L SDG S G VFE I A E 245
Cdd:COG0326 85 T R EE VIE NLGTIA K SG TRE FLE K L KGDQKKD S DL IGQFGVGFYSAFMVADKVEV VT RSA GEDAEAVR W E SDG D G EYT I E E 164
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13385998 246 A SGVRP GT K I II HLK S D CKD F AS E S R VQDVVT KYS N F VSF P LYLN G K -------- R IN TLQ A I W MMDPKD I SEFQHE EFY 317
Cdd:COG0326 165 A EKAER GT E I TL HLK E D AEE F LE E W R LREIIK KYS D F IPV P IKME G E eeeteede T IN SAT A L W TRSKSE I TDEEYK EFY 244
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13385998 318 RYIAQAYDK P R F TL H YKTDA P LNIRSIF Y V P EMK P sm FD V - S R ELGSSVA LY SRK V L I QTK A A D I LP KW LRF I RGVVDS E 396
Cdd:COG0326 245 KHLFHDFED P L F WI H LNVEG P FEYTGLL Y I P KKA P -- FD L y D R DRKGGIK LY VKR V F I MDD A E D L LP EY LRF V RGVVDS P 322
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13385998 397 D I PLN L SRE L LQE SALIR K L R DVLQQRLIKFFIDQS K K D A EKY A KF FEDY GL FMR EG IVT ta EQDIK E D IA K LLR Y ES SA 476
Cdd:COG0326 323 D L PLN V SRE I LQE DRQLK K I R KAITKKVLDELEKLA K N D R EKY E KF WKEF GL VLK EG ALE -- DFKNR E K IA D LLR F ES TK 400
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13385998 477 lp A G QLTS L PD Y AS RM QA G TRN IYY LCAPN R HL AE H SP YY E AM K Q K HT EVL FCYEQF DE LTLL HL R EFD K KK LI SV ETDI 556
Cdd:COG0326 401 -- E G GYVT L AE Y VE RM KE G QKK IYY ITGES R EA AE Q SP HL E IF K A K GI EVL LLTDPI DE FLIS HL E EFD G KK FK SV DSGD 478
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13385998 557 V vdhy KEE K F E D ts PADERLS E K E TED L MAWMRN ALG SR V TN V K V TF RL DTH PA MVTVL E MGAA R HFLR M QQLAKTQEER 636
Cdd:COG0326 479 L ---- DLD K L E E -- KKESEEE E E E FKP L LERFKE ALG DK V KD V R V SA RL TDS PA CLVAD E GDMS R RMEK M LKAMGQDMPE 552
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 13385998 637 A qll Q P T LEINP R H T L I KKL cq LR E SEP EL AQL L VDQI Y EN A MI A A G - L VD DP R A M V G RLN D LL V K V L E 704
Cdd:COG0326 553 A --- K P I LEINP N H P L V KKL -- AA E EDE EL FKD L AELL Y DQ A LL A E G g L LE DP A A F V K RLN K LL E K A L G 616
HATPase_Hsp90-like
cd16927 Histidine kinase-like ATPase domain of human cytosolic Hsp90 and its homologs including ...
97-283
1.02e-96
Histidine kinase-like ATPase domain of human cytosolic Hsp90 and its homologs including Escherichia coli HtpG, and related domains; This family includes the histidine kinase-like ATPase (HATPase) domains of 90 kilodalton heat-shock protein (Hsp90) eukaryotic homologs including cytosolic Hsp90, mitochondrial TRAP1 (tumor necrosis factor receptor-associated protein 1), GRP94 (94 kDa glucose-regulated protein) of the endoplasmic reticulum (ER), and chloroplast Hsp90C. It also includes the bacterial homologs of Hsp90, known as HtpG (High temperature protein G). Hsp90 family of chaperones assist other proteins to fold correctly, stabilizes them against heat stress, and aids in protein degradation.
Pssm-ID: 340404 [Multi-domain]
Cd Length: 189
Bit Score: 296.35
E-value: 1.02e-96
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13385998 97 KK LLD IVAR SLYS E KE V F I RELISNASDAL E KLR HKLVCEGQV L --- PE M EI HLQT D AKKG T I TI Q DTGIGMT Q EEL VS N 173
Cdd:cd16927 1 NQ LLD LIIH SLYS N KE I F L RELISNASDAL D KLR YLSLTDPSL L ddd PE L EI RISP D KENR T L TI S DTGIGMT K EEL IN N 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13385998 174 LGTIARSG S KAFLEALQ NQ A ET S S k I IGQFGVGFYSAFMVADKV E V YSR SA A p ESP GY Q W L SDG S G VFE I A EA S G - VRP G 252
Cdd:cd16927 81 LGTIARSG T KAFLEALQ EG A KD S D - L IGQFGVGFYSAFMVADKV T V TTK SA G - DDE GY R W E SDG G G SYT I E EA E G e LGR G 158
170 180 190
....*....|....*....|....*....|.
gi 13385998 253 TKI II HLK S D C K D F AS E S R VQDV V T KYS N F V 283
Cdd:cd16927 159 TKI TL HLK E D A K E F LE E A R IKEL V K KYS D F I 189
HSP90
pfam00183 Hsp90 protein;
265-699
6.48e-95
Hsp90 protein;
Pssm-ID: 459703
Cd Length: 516
Bit Score: 303.32
E-value: 6.48e-95
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13385998 265 DFAS E SRVQDV V T KYS N F VS FP L YL --------------------------- NG K ------------------------ R 293
Cdd:pfam00183 1 EYLE E KKIKEL V K KYS E F IN FP I YL wvekeeevevpdeeeeeeeeeeeeedd DP K veeedeeeekkktkkvketvwewe L 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13385998 294 I N TLQA IW MMD PK DIS E FQHE EFY RYIAQAYDK P RFTL H YKTDAPLNIR S IFYV P EMK P S - M F D v SRELGSSVA LY S R K V 372
Cdd:pfam00183 81 L N KTKP IW TRN PK EVT E EEYA EFY KSLSKDWED P LAVK H FSVEGEVEFK S LLFI P KRA P F d L F E - NKKKKNNIK LY V R R V 159
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13385998 373 L I QTKAA D IL P KW L R F IR GVVDS E D I PLN L SRE L LQ ESALIRKLRDV L QQRLIKF F IDQSKKD a E K Y A KF FEDY G LFMRE 452
Cdd:pfam00183 160 F I TDDFE D LI P EY L N F VK GVVDS D D L PLN V SRE T LQ QNKILKVIKKK L VRKALDM F KEIAEEK - E D Y K KF WKEF G KNLKL 238
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13385998 453 GI V ttaeqdik ED ------ I AKLLR YE SS ALP a GQ LTSL P DY A SRM QA G TRN IYY LCAPNRHLA E H SP YY E AM K Q K HT EV 526
Cdd:pfam00183 239 GI I -------- ED ssnrnk L AKLLR FY SS KSG - DE LTSL D DY V SRM KE G QKH IYY ITGESKEEV E N SP FL E RL K K K GY EV 309
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13385998 527 L FCYEQF DE LTLLH L R EFD K KKL IS V E tdivvdhy KE E - KF E DTSPADERLS E -- KE T E D L MA W MRNA LG SR V TN V K V TF 603
Cdd:pfam00183 310 L YLTDPI DE YAVQQ L K EFD G KKL VN V A -------- KE G l EL E EDEEEKKKDE E lk KE F E P L TK W LKDV LG DK V EK V V V SN 381
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13385998 604 RL DTH P AMVTVLEM G AARHFL R M --- Q Q L A K TQEERAQLLQP - TLEINPRH TL IK K L CQLR E SEP -- EL A QL L VDQI YE N 677
Cdd:pfam00183 382 RL VDS P CVLVTSQY G WSANME R I mka Q A L R K DSSMSSYMSSK k TLEINPRH PI IK E L LKRV E ADK dd KT A KD L ALLL YE T 461
490 500
....*....|....*....|...
gi 13385998 678 A MIAA G - LVD DP RAMVG R LNDL L 699
Cdd:pfam00183 462 A LLRS G f SLE DP ASFAS R IYRM L 484
HATPase_c
smart00387 Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
112-260
7.13e-08
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
Pssm-ID: 214643 [Multi-domain]
Cd Length: 111
Bit Score: 51.11
E-value: 7.13e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13385998 112 EVFI R ELI SN AS D ALE K LRHK lvc E G QV lpem EIH L QT D AKKGT IT IQ D T G I G MTQ E E L vsnlgtiarsg S K A F LEAL qn 191
Cdd:smart00387 3 PDRL R QVL SN LL D NAI K YTPE --- G G RI ---- TVT L ER D GDHVE IT VE D N G P G IPP E D L ----------- E K I F EPFF -- 62
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 13385998 192 QAETS S KI IG QF G V G FYSAFMVADKVEV ysrsaapespgyqwlsdgsgvf EI AEA S GVRP GT KII I H L K 260
Cdd:smart00387 63 RTDKR S RK IG GT G L G LSIVKKLVELHGG ---------------------- EI SVE S EPGG GT TFT I T L P 109
Name
Accession
Description
Interval
E-value
PRK05218
PRK05218 heat shock protein 90; Provisional
89-704
0e+00
heat shock protein 90; Provisional
Pssm-ID: 235366 [Multi-domain]
Cd Length: 613
Bit Score: 699.17
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13385998 89 KH EFQAE T K K LL DIVAR SLYS E KE V F I RELISNASDA LE KLR HKLVCEGQVL --- PEME I HLQT D AKKG T I TI Q D T GIGM 165
Cdd:PRK05218 5 TG EFQAE V K Q LL HLMIH SLYS N KE I F L RELISNASDA ID KLR FEALTDPALY egd GDLK I RISF D KEAR T L TI S D N GIGM 84
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13385998 166 T Q EE LVS NLGTIA R SG S K A FLE A L QNQAETS S KI IGQFGVGFYSAFMVADKV E V YS RSA A P ESPGYQ W L SDG S G VFE I A E 245
Cdd:PRK05218 85 T R EE VIE NLGTIA K SG T K E FLE K L KGDQKKD S QL IGQFGVGFYSAFMVADKV T V IT RSA G P AAEAVR W E SDG E G EYT I E E 164
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13385998 246 ASGVRP GT K I II HLK S D CKD F AS E S R VQDVVT KYS N F VSF P LY L NGK --- R IN TLQ A I W MMDPKD I SEFQHE EFY RYI A Q 322
Cdd:PRK05218 165 IEKEER GT E I TL HLK E D EDE F LD E W R IRSIIK KYS D F IPV P IK L EKE eee T IN SAS A L W TRSKSE I TDEEYK EFY KHL A H 244
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13385998 323 AY D K P R F TL H YKTDA P LNIRSIF Y V P EMK P sm FD V - S R ELGSSVA LY SRK V L I QTK A ADI LP KW LRF IR GV V DSED I PLN 401
Cdd:PRK05218 245 DF D D P L F WI H NNVEG P FEYTGLL Y I P KKA P -- FD L f N R DRKGGLK LY VKR V F I MDD A EEL LP EY LRF VK GV I DSED L PLN 322
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13385998 402 L SRE L LQE SALIR K L R DVLQQRLIKFFIDQS K K D A EKY A KF FEDY G LFMR EG IVTTAEQ di K E DI AKLLR YE S SA lp A G Q 481
Cdd:PRK05218 323 V SRE I LQE DRVVK K I R KAITKKVLDELEKLA K N D R EKY E KF WKEF G PVLK EG LYEDFAN -- R E KL AKLLR FA S TH -- E G K 398
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13385998 482 LT SL PD Y AS RM QA G TRN IYY LCAPN R HL A EH SP YY E AM K Q K HT EVL FCYEQF DE LTLLH L R EFD K K KLI SV e TDIVV D HY 561
Cdd:PRK05218 399 YV SL AE Y VE RM KE G QKK IYY ITGDS R EA A KN SP HL E LF K K K GI EVL LLTDPI DE FWISY L E EFD G K PFK SV - ARGDL D LG 477
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13385998 562 KE EKF E DTSPADE rls E K E TED L MAWMRN ALG SR V TN V KVTF RL DTH PA MVTVL E MG aarhfl RMQ Q LA K TQEERA Q LL - 640
Cdd:PRK05218 478 KE DEE E KEEKEEA --- E E E FKP L LERLKE ALG DK V KD V RLSH RL TDS PA CLVAD E GD ------ MST Q ME K LLKAAG Q EV p 548
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 13385998 641 -- Q P T LEINP R H T L I KKL cq LR E SEPELAQL L VDQI Y EN A MI A A G L - VD DP R A M V G RLN D LL V K V L E 704
Cdd:PRK05218 549 es K P I LEINP N H P L V KKL -- AD E ADEAKFKD L AELL Y DQ A LL A E G G s LE DP A A F V K RLN E LL L K L L A 613
HtpG
COG0326 Molecular chaperone, HSP90 family [Posttranslational modification, protein turnover, ...
89-704
0e+00
Molecular chaperone, HSP90 family [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440095 [Multi-domain]
Cd Length: 616
Bit Score: 691.86
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13385998 89 KH EFQAE T K K LLD IVAR SLYS E KE V F I RELISNASDA LE KLR HKLVCEGQVL --- PEME I HLQT D AKKG T I TI Q D T GIGM 165
Cdd:COG0326 5 TG EFQAE V K Q LLD LMIH SLYS N KE I F L RELISNASDA ID KLR FLALTDPELK eed GDLK I RIEV D KEAK T L TI S D N GIGM 84
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13385998 166 T Q EE LVS NLGTIA R SG SKA FLE A L QNQAETS S KI IGQFGVGFYSAFMVADKVEV YS RSA APESPGYQ W L SDG S G VFE I A E 245
Cdd:COG0326 85 T R EE VIE NLGTIA K SG TRE FLE K L KGDQKKD S DL IGQFGVGFYSAFMVADKVEV VT RSA GEDAEAVR W E SDG D G EYT I E E 164
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13385998 246 A SGVRP GT K I II HLK S D CKD F AS E S R VQDVVT KYS N F VSF P LYLN G K -------- R IN TLQ A I W MMDPKD I SEFQHE EFY 317
Cdd:COG0326 165 A EKAER GT E I TL HLK E D AEE F LE E W R LREIIK KYS D F IPV P IKME G E eeeteede T IN SAT A L W TRSKSE I TDEEYK EFY 244
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13385998 318 RYIAQAYDK P R F TL H YKTDA P LNIRSIF Y V P EMK P sm FD V - S R ELGSSVA LY SRK V L I QTK A A D I LP KW LRF I RGVVDS E 396
Cdd:COG0326 245 KHLFHDFED P L F WI H LNVEG P FEYTGLL Y I P KKA P -- FD L y D R DRKGGIK LY VKR V F I MDD A E D L LP EY LRF V RGVVDS P 322
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13385998 397 D I PLN L SRE L LQE SALIR K L R DVLQQRLIKFFIDQS K K D A EKY A KF FEDY GL FMR EG IVT ta EQDIK E D IA K LLR Y ES SA 476
Cdd:COG0326 323 D L PLN V SRE I LQE DRQLK K I R KAITKKVLDELEKLA K N D R EKY E KF WKEF GL VLK EG ALE -- DFKNR E K IA D LLR F ES TK 400
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13385998 477 lp A G QLTS L PD Y AS RM QA G TRN IYY LCAPN R HL AE H SP YY E AM K Q K HT EVL FCYEQF DE LTLL HL R EFD K KK LI SV ETDI 556
Cdd:COG0326 401 -- E G GYVT L AE Y VE RM KE G QKK IYY ITGES R EA AE Q SP HL E IF K A K GI EVL LLTDPI DE FLIS HL E EFD G KK FK SV DSGD 478
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13385998 557 V vdhy KEE K F E D ts PADERLS E K E TED L MAWMRN ALG SR V TN V K V TF RL DTH PA MVTVL E MGAA R HFLR M QQLAKTQEER 636
Cdd:COG0326 479 L ---- DLD K L E E -- KKESEEE E E E FKP L LERFKE ALG DK V KD V R V SA RL TDS PA CLVAD E GDMS R RMEK M LKAMGQDMPE 552
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 13385998 637 A qll Q P T LEINP R H T L I KKL cq LR E SEP EL AQL L VDQI Y EN A MI A A G - L VD DP R A M V G RLN D LL V K V L E 704
Cdd:COG0326 553 A --- K P I LEINP N H P L V KKL -- AA E EDE EL FKD L AELL Y DQ A LL A E G g L LE DP A A F V K RLN K LL E K A L G 616
PTZ00272
PTZ00272 heat shock protein 83 kDa (Hsp83); Provisional
92-699
1.28e-129
heat shock protein 83 kDa (Hsp83); Provisional
Pssm-ID: 240341
Cd Length: 701
Bit Score: 399.82
E-value: 1.28e-129
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13385998 92 FQAE TKK L LDIVARSL YS E KE V F I RELISNASDA LE K L R HKLVCEGQ VL --- P EME I HLQT D AKKG T I T IQ D T GIGMT QE 168
Cdd:PTZ00272 7 FQAE INQ L MSLIINTF YS N KE I F L RELISNASDA CD K I R YQSLTDPS VL ges P RLC I RVVP D KENK T L T VE D N GIGMT KA 86
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13385998 169 E LV S NLGTIARSG S KAF L EAL QNQAET S sk I IGQFGVGFYSA FM VAD K V E V Y S RSAAP ES pg Y Q W L S DGS G V F E I AEA -- 246
Cdd:PTZ00272 87 D LV N NLGTIARSG T KAF M EAL EAGGDM S -- M IGQFGVGFYSA YL VAD R V T V T S KNNSD ES -- Y V W E S SAG G T F T I TST pe 162
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13385998 247 S GVRP GT K I II HLK S D CKDFASES R VQDVVT K Y S N F VSFPLY L ------------------------------------- 289
Cdd:PTZ00272 163 S DMKR GT R I TL HLK E D QMEYLEPR R LKELIK K H S E F IGYDIE L mvekttekevtdedeedtkkadedgeepkveevkegd 242
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13385998 290 ----- NG K RI ---------- N TLQAI W MM DPKD ISEFQHEE FY RY I AQAYDK P RF T L H YKTDAP L NI RSI FY VP EMK P - S 353
Cdd:PTZ00272 243 egkkk KT K KV kevtkeyevq N KHKPL W TR DPKD VTKEEYAA FY KA I SNDWED P AA T K H FSVEGQ L EF RSI MF VP KRA P f D 322
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13385998 354 MF DVSREL g SSVA LY S R K V L I QTKAA D IL P K WL R F IR GVVDSED I PLN L SRE L LQ ESALIRKL R DVLQQRLIKF F i D QSK 433
Cdd:PTZ00272 323 MF EPNKKR - NNIK LY V R R V F I MDNCE D LC P D WL G F VK GVVDSED L PLN I SRE N LQ QNKILKVI R KNIVKKCLEM F - D EVA 400
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13385998 434 KDA E K Y AK F F E DY G LFMRE GI VTTAEQ di KEDIAK LLR YE S SA l PAGQL T S L P DY AS RM Q AG TRN IYY LCAPNRHLA E H S 513
Cdd:PTZ00272 401 ENK E D Y KQ F Y E QF G KNIKL GI HEDTAN -- RKKLME LLR FY S TE - SGEEM T T L K DY VT RM K AG QKS IYY ITGDSKKKL E T S 477
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13385998 514 P YY E AMKQKHT EVLF CY E QF DE LTLLHLRE F DK KK LISVETDI V vd H YK E EKF E DTSPAD E RLS eke T E D L MAW M RNA LG 593
Cdd:PTZ00272 478 P FI E QARRRGL EVLF MT E PI DE YVMQQVKD F ED KK FACLTKEG V -- H FE E SEE E KQQREE E KAA --- C E K L CKT M KEV LG 552
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13385998 594 SR V TN V K V TF RL D T H P AMVTVL E M G AAR H F --- L R M Q Q L AKTQEERAQLLQP T L E I NPRH TL IK K L CQLRESEP -- ELAQ 668
Cdd:PTZ00272 553 DK V EK V I V SE RL S T S P CILVTS E F G WSA H M eqi M R N Q A L RDSSMAQYMMSKK T M E L NPRH PI IK E L RRRVGADE nd KAVK 632
650 660 670
....*....|....*....|....*....|..
gi 13385998 669 L LV DQIYENAMIAA G L - VD DP RAMVG R L N DLL 699
Cdd:PTZ00272 633 D LV FLLFDTSLLTS G F q LE DP TGYAE R I N RMI 664
PTZ00130
PTZ00130 heat shock protein 90; Provisional
61-684
1.81e-102
heat shock protein 90; Provisional
Pssm-ID: 185466 [Multi-domain]
Cd Length: 814
Bit Score: 332.01
E-value: 1.81e-102
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13385998 61 STQAA E D K EEESLHSI I SNT E AVRGSVSK H EF Q A E TKK L L DI VAR SLY SE KEVF I RELISNA S DALEK L R HKLVCEGQ VL 140
Cdd:PTZ00130 39 KEEKE E V K KDRDNIPE I EDG E KPTSGIEQ H QY Q T E VTR L M DI IVN SLY TQ KEVF L RELISNA A DALEK I R FLSLSDES VL 118
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13385998 141 P E --- M EI HLQTDAK K GTIT I Q DTGIGMT Q E E L VS NLGTIA R SG SKA FLEA LQNQAETS S k I IGQFGVGFYSAF M VADKV 217
Cdd:PTZ00130 119 G E ekk L EI RISANKE K NILS I T DTGIGMT K E D L IN NLGTIA K SG TSN FLEA ISKSGGDM S - L IGQFGVGFYSAF L VADKV 197
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13385998 218 E VY SRSAAP E S pg Y Q W L S DGSGV F E I --- AEA S GVRP GT K I II HLK S D CKDFASESRVQ D VVT KYS N F VSF P L YL ----- 289
Cdd:PTZ00130 198 I VY TKNNND E Q -- Y I W E S TADAK F T I ykd PRG S TLKR GT R I SL HLK E D ATNLMNDKKLV D LIS KYS Q F IQY P I YL lhenv 275
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13385998 290 ------------------------------------------ NG K RI N TLQA IW MMD PK DISEFQHEE F YRYIAQAY D K P 327
Cdd:PTZ00130 276 yteevladiakemendpnydsvkveetddpnkktrtvekkvk KW K LM N EQKP IW LRP PK ELTDEDYKK F FSVLSGFN D E P 355
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13385998 328 RFTL H YKTDAPLNIRSIF Y V P EMK PS MF D VSRELGS S VA LY S R K VL IQTKAADI LP KWLR F IR GVVDS E D I PLN L SRE L L 407
Cdd:PTZ00130 356 LYHI H FFAEGEIEFKCLI Y I P SRA PS IN D HLFTKQN S IK LY V R R VL VADEFVEF LP RYMS F VK GVVDS D D L PLN V SRE Q L 435
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13385998 408 Q ESA -------- LI RK LR D V -------------- L QQR L I K FFIDQS KK DAE K ------- Y AKFFED Y GLFMRE G IV tta 458
Cdd:PTZ00130 436 Q QNK ilkavskr IV RK IL D T frtlykegkknket L RAE L A K ETDEEK KK EIQ K kinepst Y KLIYKE Y RKYLKT G CY --- 512
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13385998 459 E Q DI - KED I A KLL RYESSAL P AG ql T SL PD Y ASR M QAGTRN IYY LCAPNRHLAEHS P YYEAM K Q K HTE V L F CY E QF DE LT 537
Cdd:PTZ00130 513 E D DI n RNK I V KLL LFKTMLH P KS -- I SL DT Y IEN M KPDQKF IYY ASGDSYEYLSKI P QLQIF K K K NID V V F LT E SV DE SC 590
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13385998 538 LLHLR E F D K KK LI S VET - D I VVDHYKE EK fedtsp AD E RLSE K ETED L MAWMRNA L GSRVTN V KVTF RL DTH P AM V TVL E 616
Cdd:PTZ00130 591 VQRVQ E Y D G KK FK S IQK g E I TFELTED EK ------ KK E EKVK K MYKA L IDVISDT L RNQIFK V EISR RL VDA P CA V VST E 664
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 13385998 617 M G AARHFLRMQQLAKTQEERAQLL -- Q PT LEINP R H TLIKK L CQLRE S E P ELA QL L -- VDQ IY EN A MI A A G L 684
Cdd:PTZ00130 665 W G LSGQMEKLMKINVNNSDQIKAM sg Q KI LEINP D H PIMID L LKRSV S N P KDS QL T es IKI IY QS A KL A S G F 736
HATPase_Hsp90-like
cd16927 Histidine kinase-like ATPase domain of human cytosolic Hsp90 and its homologs including ...
97-283
1.02e-96
Histidine kinase-like ATPase domain of human cytosolic Hsp90 and its homologs including Escherichia coli HtpG, and related domains; This family includes the histidine kinase-like ATPase (HATPase) domains of 90 kilodalton heat-shock protein (Hsp90) eukaryotic homologs including cytosolic Hsp90, mitochondrial TRAP1 (tumor necrosis factor receptor-associated protein 1), GRP94 (94 kDa glucose-regulated protein) of the endoplasmic reticulum (ER), and chloroplast Hsp90C. It also includes the bacterial homologs of Hsp90, known as HtpG (High temperature protein G). Hsp90 family of chaperones assist other proteins to fold correctly, stabilizes them against heat stress, and aids in protein degradation.
Pssm-ID: 340404 [Multi-domain]
Cd Length: 189
Bit Score: 296.35
E-value: 1.02e-96
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13385998 97 KK LLD IVAR SLYS E KE V F I RELISNASDAL E KLR HKLVCEGQV L --- PE M EI HLQT D AKKG T I TI Q DTGIGMT Q EEL VS N 173
Cdd:cd16927 1 NQ LLD LIIH SLYS N KE I F L RELISNASDAL D KLR YLSLTDPSL L ddd PE L EI RISP D KENR T L TI S DTGIGMT K EEL IN N 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13385998 174 LGTIARSG S KAFLEALQ NQ A ET S S k I IGQFGVGFYSAFMVADKV E V YSR SA A p ESP GY Q W L SDG S G VFE I A EA S G - VRP G 252
Cdd:cd16927 81 LGTIARSG T KAFLEALQ EG A KD S D - L IGQFGVGFYSAFMVADKV T V TTK SA G - DDE GY R W E SDG G G SYT I E EA E G e LGR G 158
170 180 190
....*....|....*....|....*....|.
gi 13385998 253 TKI II HLK S D C K D F AS E S R VQDV V T KYS N F V 283
Cdd:cd16927 159 TKI TL HLK E D A K E F LE E A R IKEL V K KYS D F I 189
HSP90
pfam00183 Hsp90 protein;
265-699
6.48e-95
Hsp90 protein;
Pssm-ID: 459703
Cd Length: 516
Bit Score: 303.32
E-value: 6.48e-95
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13385998 265 DFAS E SRVQDV V T KYS N F VS FP L YL --------------------------- NG K ------------------------ R 293
Cdd:pfam00183 1 EYLE E KKIKEL V K KYS E F IN FP I YL wvekeeevevpdeeeeeeeeeeeeedd DP K veeedeeeekkktkkvketvwewe L 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13385998 294 I N TLQA IW MMD PK DIS E FQHE EFY RYIAQAYDK P RFTL H YKTDAPLNIR S IFYV P EMK P S - M F D v SRELGSSVA LY S R K V 372
Cdd:pfam00183 81 L N KTKP IW TRN PK EVT E EEYA EFY KSLSKDWED P LAVK H FSVEGEVEFK S LLFI P KRA P F d L F E - NKKKKNNIK LY V R R V 159
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13385998 373 L I QTKAA D IL P KW L R F IR GVVDS E D I PLN L SRE L LQ ESALIRKLRDV L QQRLIKF F IDQSKKD a E K Y A KF FEDY G LFMRE 452
Cdd:pfam00183 160 F I TDDFE D LI P EY L N F VK GVVDS D D L PLN V SRE T LQ QNKILKVIKKK L VRKALDM F KEIAEEK - E D Y K KF WKEF G KNLKL 238
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13385998 453 GI V ttaeqdik ED ------ I AKLLR YE SS ALP a GQ LTSL P DY A SRM QA G TRN IYY LCAPNRHLA E H SP YY E AM K Q K HT EV 526
Cdd:pfam00183 239 GI I -------- ED ssnrnk L AKLLR FY SS KSG - DE LTSL D DY V SRM KE G QKH IYY ITGESKEEV E N SP FL E RL K K K GY EV 309
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13385998 527 L FCYEQF DE LTLLH L R EFD K KKL IS V E tdivvdhy KE E - KF E DTSPADERLS E -- KE T E D L MA W MRNA LG SR V TN V K V TF 603
Cdd:pfam00183 310 L YLTDPI DE YAVQQ L K EFD G KKL VN V A -------- KE G l EL E EDEEEKKKDE E lk KE F E P L TK W LKDV LG DK V EK V V V SN 381
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13385998 604 RL DTH P AMVTVLEM G AARHFL R M --- Q Q L A K TQEERAQLLQP - TLEINPRH TL IK K L CQLR E SEP -- EL A QL L VDQI YE N 677
Cdd:pfam00183 382 RL VDS P CVLVTSQY G WSANME R I mka Q A L R K DSSMSSYMSSK k TLEINPRH PI IK E L LKRV E ADK dd KT A KD L ALLL YE T 461
490 500
....*....|....*....|...
gi 13385998 678 A MIAA G - LVD DP RAMVG R LNDL L 699
Cdd:pfam00183 462 A LLRS G f SLE DP ASFAS R IYRM L 484
PRK14083
PRK14083 HSP90 family protein; Provisional
90-442
3.31e-43
HSP90 family protein; Provisional
Pssm-ID: 237603 [Multi-domain]
Cd Length: 601
Bit Score: 165.11
E-value: 3.31e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13385998 90 H E FQ AETKKLL D IVA R S LYS EKE V FI REL IS NA S DA LEKL R hklvc EGQVLPEME I HLQ - TDA KK GT ITIQ D T GIG M T Q E 168
Cdd:PRK14083 3 H R FQ VDLRGVI D LLS R H LYS SPR V YV REL LQ NA V DA ITAR R ----- ALDPTAPGR I RIE l TDA GG GT LIVE D N GIG L T E E 77
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13385998 169 E LVSN L G TI A RS g SK A fl EALQNQ A et SSKII GQFG V G FY S A F M VAD KVE V Y SRSA A p ES P GYQ W L -- S DG SGVFEIA E A 246
Cdd:PRK14083 78 E VHEF L A TI G RS - SK R -- DENLGF A -- RNDFL GQFG I G LL S C F L VAD EIV V V SRSA K - DG P AVE W R gk A DG TYSVRKL E T 151
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13385998 247 SGVR PGT KIIIHLKS D CKDFASESR V QDVVT KY SNFVSF P LYLN G -- KRI N TLQAI W MM D PK D ISEFQ h E EFYR Y IAQAY 324
Cdd:PRK14083 152 ERAE PGT TVYLRPRP D AEEWLERET V EELAK KY GSLLPV P IRVE G ek GGV N ETPPP W TR D YP D PETRR - E ALLA Y GEELL 230
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13385998 325 DKPRF tlhykt D A - PL N ----- IRSIF YV PEMKP S M fdv SRELGSS V al Y SRKV L IQTK A ADI LP K W LR F I R G VV DSEDI 398
Cdd:PRK14083 231 GFTPL ------ D V i PL D vpsgg LEGVA YV LPYAV S P --- AARRKHR V -- Y LKRM L LSEE A ENL LP D W AF F V R C VV NTDEL 299
330 340 350 360
....*....|....*....|....*....|....*....|....
gi 13385998 399 PLNL SRE L L Q E SALIRKL R DV L QQRLI K FF I DQSKK D A E KYAKF 442
Cdd:PRK14083 300 RPTA SRE A L Y E DDALAAV R EE L GEAIR K WL I GLATT D P E RLRRL 343
HATPase_c
smart00387 Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
112-260
7.13e-08
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
Pssm-ID: 214643 [Multi-domain]
Cd Length: 111
Bit Score: 51.11
E-value: 7.13e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13385998 112 EVFI R ELI SN AS D ALE K LRHK lvc E G QV lpem EIH L QT D AKKGT IT IQ D T G I G MTQ E E L vsnlgtiarsg S K A F LEAL qn 191
Cdd:smart00387 3 PDRL R QVL SN LL D NAI K YTPE --- G G RI ---- TVT L ER D GDHVE IT VE D N G P G IPP E D L ----------- E K I F EPFF -- 62
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 13385998 192 QAETS S KI IG QF G V G FYSAFMVADKVEV ysrsaapespgyqwlsdgsgvf EI AEA S GVRP GT KII I H L K 260
Cdd:smart00387 63 RTDKR S RK IG GT G L G LSIVKKLVELHGG ---------------------- EI SVE S EPGG GT TFT I T L P 109
HATPase_TopVIB-like
cd16933 Histidine kinase-like ATPase domain of type IIB topoisomerase, Topo VI, subunit B; This family ...
91-222
3.49e-07
Histidine kinase-like ATPase domain of type IIB topoisomerase, Topo VI, subunit B; This family includes the histidine kinase-like ATPase (HATPase) domain of the B subunit of topoisomerase VI (Topo VIB). Topo VI is a heterotetrameric complex composed of two TopVIA and two TopVIB subunits and is categorized as a type II B DNA topoisomerase. It is found in archaea and also in plants. Type II enzymes cleave both strands of a DNA duplex and pass a second duplex through the resulting break in an ATP-dependent mechanism. DNA cleavage by Topo VI generates two-nucleotide 5'-protruding ends.
Pssm-ID: 340410 [Multi-domain]
Cd Length: 203
Bit Score: 51.19
E-value: 3.49e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13385998 91 EF QAET K KL L -- D IVA RSLY S ekev FI REL IS N AS DA L E klrhklvc E GQV LP EMEIHL - QTDAKKGTITIQ D T G I G MTQ 167
Cdd:cd16933 2 EF FRKN K EM L gf D NPI RSLY T ---- TV REL VE N SL DA T E -------- E AGI LP DIKVEI e EIGKDHYKVIVE D N G P G IPE 69
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 13385998 168 E ELVSNL G TIA r S GSK AFLE al Q NQ aetsskii GQ F G V G FYS A F ---- M VAD K - VE VY S R 222
Cdd:cd16933 70 E QIPKVF G KVL - Y GSK YHNK -- Q SR -------- GQ Q G L G ISA A V lysq M TTG K p VE II S S 118
HATPase_c_3
pfam13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents, additionally, ...
112-222
7.09e-06
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents, additionally, the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.
Pssm-ID: 433332 [Multi-domain]
Cd Length: 135
Bit Score: 46.17
E-value: 7.09e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13385998 112 E VFIR ELI S N AS DA leklrhklvcegq VLPEME I HLQTDAKK GT - I T I Q D T G I GM TQ EEL VSN L G t I A R S GSK aflealq 190
Cdd:pfam13589 2 E GALA ELI D N SI DA ------------- DATNIK I EVNKNRGG GT e I V I E D D G H GM SP EEL INA L R - L A T S AKE ------- 60
90 100 110
....*....|....*....|....*....|...
gi 13385998 191 nq A ETS S KII G QF G V G FYS A - FMVAD K VE V Y S R 222
Cdd:pfam13589 61 -- A KRG S TDL G RY G I G LKL A s LSLGA K LT V T S K 91
HATPase_MutL-MLH-PMS-like
cd16926 Histidine kinase-like ATPase domain of DNA mismatch repair proteins Escherichia coli MutL, ...
115-294
3.72e-04
Histidine kinase-like ATPase domain of DNA mismatch repair proteins Escherichia coli MutL, human MutL homologs (MLH/ PMS), and related domains; This family includes the histidine kinase-like ATPase (HATPase) domains of Escherichia coli MutL, human MLH1 (mutL homolog 1), human PMS1 (PMS1 homolog 1, mismatch repair system component), human MLH3 (mutL homolog 3), and human PMS2 (PMS1 homolog 2, mismatch repair system component). MutL homologs (MLH/PMS) participate in MMR (DNA mismatch repair), and in addition have role(s) in DNA damage signaling and suppression of homologous recombination (recombination between partially homologous parental DNAs). The primary role of MutL in MMR is to mediate protein-protein interactions during mismatch recognition and strand removal; a ternary complex is formed between MutS, MutL, and the mismatched DNA, which activates the MutH endonuclease.
Pssm-ID: 340403 [Multi-domain]
Cd Length: 188
Bit Score: 42.04
E-value: 3.72e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13385998 115 IR EL IS N AS DA LEK lrhklvcegqvlp EMEIHLQ t DAKKGT I TIQ D T G I G MTQ E E L V snlgtiarsgs K AF LE alqnqa E 194
Cdd:cd16926 18 VK EL VE N SI DA GAT ------------- RIDVEIE - EGGLKL I RVT D N G S G ISR E D L E ----------- L AF ER ------ H 66
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13385998 195 TS SKI -------- I GQF gv GF ----- Y S AFM V A d KVEVYS R S A APES p G YQWLS DG S G VF E IAEASGVRP GT KIIIH --- 258
Cdd:cd16926 67 AT SKI ssfedlfs I TTL -- GF rgeal A S IAS V S - RLTITT R T A DDDV - G TRLVV DG G G II E EVKPAAAPV GT TVTVR dlf 142
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 13385998 259 --------- LKS DCKDF ase S RVQ D V V TKYS --- NF VSF P L YLN GK RI 294
Cdd:cd16926 143 yntparrkf LKS PKTEL --- S KIL D L V QRLA lah PD VSF S L THD GK LV 187
COG4191
COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal ...
118-170
3.11e-03
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal transduction mechanisms];
Pssm-ID: 443345 [Multi-domain]
Cd Length: 361
Bit Score: 40.55
E-value: 3.11e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 13385998 118 L IS NA S DA L E KLRH klvcegqvl PEME I HLQTDAKKGT I TIQ D T G I G MTQ E E L 170
Cdd:COG4191 264 L LI NA I DA M E EGEG --------- GRIT I STRREGDYVV I SVR D N G P G IPP E V L 307
KinB
COG5806 Sporulation sensor histidine kinase B [Cell cycle control, cell division, chromosome ...
145-176
5.69e-03
Sporulation sensor histidine kinase B [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444508 [Multi-domain]
Cd Length: 412
Bit Score: 39.85
E-value: 5.69e-03
10 20 30
....*....|....*....|....*....|..
gi 13385998 145 I HLQT D AK K GT I T I Q DTG I GMT Q E E L v SN LG T 176
Cdd:COG5806 335 I DVSI D KN K VI I S I K DTG V GMT K E Q L - ER LG E 365
HATPase_c
pfam02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the ...
110-170
8.72e-03
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.
Pssm-ID: 460579 [Multi-domain]
Cd Length: 109
Bit Score: 36.58
E-value: 8.72e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 13385998 110 EK E VFI R ELI SN AS D AL ek L R H KLVCE gqvlp E MEIH L QTDAK k G T I T IQ D T GIG MTQ E E L 170
Cdd:pfam02518 1 GD E LRL R QVL SN LL D NA -- L K H AAKAG ----- E ITVT L SEGGE - L T L T VE D N GIG IPP E D L 53
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
