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Conserved domains on  [gi|226437608|ref|NP_080386|]
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PAX3- and PAX7-binding protein 1 [Mus musculus]

Protein Classification

GCFC domain-containing protein( domain architecture ID 10545165)

GCFC domain-containing protein

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
GCFC pfam07842
GC-rich sequence DNA-binding factor-like protein; This entry describes a domain found in a ...
597-808 3.10e-44

GC-rich sequence DNA-binding factor-like protein; This entry describes a domain found in a number of GC-rich sequence DNA-binding factor proteins and homologs, as well as in a number of other proteins including Tuftelin-interacting protein 11. While the function of the domain is unknown, some of the proteins it is found in are reported to be involved in pre-mRNA splicing. This domain is also found in Sip1, a septin interacting protein.


:

Pssm-ID: 400273  Cd Length: 275  Bit Score: 161.47  E-value: 3.10e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226437608  597 IDCIKAQFEAWRSKYYMSYKDAYIGLCLPKLFNPLIRLQLLTWTPLEAKCR----------------------------D 648
Cdd:pfam07842   1 LDEIADIFERLQRKYPEEYKEAELSLLAPSLVHPLLRLELLEWDPLKDPTYgvdilsrwrkllepdvssddtggresmdP 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226437608  649 FETMLWFESLLFYGCEDREQE---KDEADVALLP------------TIVEKVILPKLTVIAETmWDPFSTTQTSRMVGIT 713
Cdd:pfam07842  81 YETMLWEGWLPSYRSSIISTWdprDPDPMLALLEawapllpswildNILEQLILPKLTAAVEE-WDPLSDTVTRNLVPIH 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226437608  714 MKLINGYPSVvnadNKNTQVYLKALLLRMRRTLDD---------------DVFMP-LYPKNVLENKNSGPYLFFQ----- 772
Cdd:pfam07842 160 SWIHPWLPLL----GARLEPLYPDIRRKLRQALDAwhpsrsalaglkpwkDVFSPgEWDKFLRRHILPKLALALQefvin 235
                         250       260       270
                  ....*....|....*....|....*....|....*..
gi 226437608  773 -RQfwSSVKLLGNFLQWYGIFSNKTLQELSIDGLLNR 808
Cdd:pfam07842 236 pRQ--QSLELFRNVLKWKDLLPPSVLADLLEKEFFPK 270
 
Name Accession Description Interval E-value
GCFC pfam07842
GC-rich sequence DNA-binding factor-like protein; This entry describes a domain found in a ...
597-808 3.10e-44

GC-rich sequence DNA-binding factor-like protein; This entry describes a domain found in a number of GC-rich sequence DNA-binding factor proteins and homologs, as well as in a number of other proteins including Tuftelin-interacting protein 11. While the function of the domain is unknown, some of the proteins it is found in are reported to be involved in pre-mRNA splicing. This domain is also found in Sip1, a septin interacting protein.


Pssm-ID: 400273  Cd Length: 275  Bit Score: 161.47  E-value: 3.10e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226437608  597 IDCIKAQFEAWRSKYYMSYKDAYIGLCLPKLFNPLIRLQLLTWTPLEAKCR----------------------------D 648
Cdd:pfam07842   1 LDEIADIFERLQRKYPEEYKEAELSLLAPSLVHPLLRLELLEWDPLKDPTYgvdilsrwrkllepdvssddtggresmdP 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226437608  649 FETMLWFESLLFYGCEDREQE---KDEADVALLP------------TIVEKVILPKLTVIAETmWDPFSTTQTSRMVGIT 713
Cdd:pfam07842  81 YETMLWEGWLPSYRSSIISTWdprDPDPMLALLEawapllpswildNILEQLILPKLTAAVEE-WDPLSDTVTRNLVPIH 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226437608  714 MKLINGYPSVvnadNKNTQVYLKALLLRMRRTLDD---------------DVFMP-LYPKNVLENKNSGPYLFFQ----- 772
Cdd:pfam07842 160 SWIHPWLPLL----GARLEPLYPDIRRKLRQALDAwhpsrsalaglkpwkDVFSPgEWDKFLRRHILPKLALALQefvin 235
                         250       260       270
                  ....*....|....*....|....*....|....*..
gi 226437608  773 -RQfwSSVKLLGNFLQWYGIFSNKTLQELSIDGLLNR 808
Cdd:pfam07842 236 pRQ--QSLELFRNVLKWKDLLPPSVLADLLEKEFFPK 270
 
Name Accession Description Interval E-value
GCFC pfam07842
GC-rich sequence DNA-binding factor-like protein; This entry describes a domain found in a ...
597-808 3.10e-44

GC-rich sequence DNA-binding factor-like protein; This entry describes a domain found in a number of GC-rich sequence DNA-binding factor proteins and homologs, as well as in a number of other proteins including Tuftelin-interacting protein 11. While the function of the domain is unknown, some of the proteins it is found in are reported to be involved in pre-mRNA splicing. This domain is also found in Sip1, a septin interacting protein.


Pssm-ID: 400273  Cd Length: 275  Bit Score: 161.47  E-value: 3.10e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226437608  597 IDCIKAQFEAWRSKYYMSYKDAYIGLCLPKLFNPLIRLQLLTWTPLEAKCR----------------------------D 648
Cdd:pfam07842   1 LDEIADIFERLQRKYPEEYKEAELSLLAPSLVHPLLRLELLEWDPLKDPTYgvdilsrwrkllepdvssddtggresmdP 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226437608  649 FETMLWFESLLFYGCEDREQE---KDEADVALLP------------TIVEKVILPKLTVIAETmWDPFSTTQTSRMVGIT 713
Cdd:pfam07842  81 YETMLWEGWLPSYRSSIISTWdprDPDPMLALLEawapllpswildNILEQLILPKLTAAVEE-WDPLSDTVTRNLVPIH 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226437608  714 MKLINGYPSVvnadNKNTQVYLKALLLRMRRTLDD---------------DVFMP-LYPKNVLENKNSGPYLFFQ----- 772
Cdd:pfam07842 160 SWIHPWLPLL----GARLEPLYPDIRRKLRQALDAwhpsrsalaglkpwkDVFSPgEWDKFLRRHILPKLALALQefvin 235
                         250       260       270
                  ....*....|....*....|....*....|....*..
gi 226437608  773 -RQfwSSVKLLGNFLQWYGIFSNKTLQELSIDGLLNR 808
Cdd:pfam07842 236 pRQ--QSLELFRNVLKWKDLLPPSVLADLLEKEFFPK 270
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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