|
Name |
Accession |
Description |
Interval |
E-value |
| CCDC144C |
pfam14915 |
CCDC144C protein coiled-coil region; This family includes the human protein CCDC144C and the ... |
821-1123 |
2.38e-138 |
|
CCDC144C protein coiled-coil region; This family includes the human protein CCDC144C and the ankyrin repeat domain-containing protein 26-like 1 found in eukaryotes. Its function remains unknown, however, it is known to contain a coiled-coil domain which corresponds to this region. The ankyrin repeat which features in this protein is a common amino acid motif.
Pssm-ID: 464371 [Multi-domain] Cd Length: 304 Bit Score: 426.33 E-value: 2.38e-138
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 821 DCMLQEEIALLRLEIDTIKNQNKQKEKKYFEDIEAVKEKNDNLQKIIKLNEETLTETILQYSGQLNNLTAENKILNSELE 900
Cdd:pfam14915 1 NCMLQDEIAMLRLEIDTIKNQNQEKEKKYLEDIEILKEKNDDLQKTLKLNEETLTKTVFQYNGQLNVLKAENTMLNSKLE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 901 NGKQNQERLEIEMESYRCRLAAAVRDCDQSQTA-RDLKLDFQRTRQEWVRLHDKMKVDMSGLQAKNEILSEKLSNAESKI 979
Cdd:pfam14915 81 NEKQNKERLETEVESYRSRLAAAIQDHEQSQTSkRDLELAFQRERDEWLRLQDKMNFDVSNLRDENEILSQQLSKAESKA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 980 NSLQIQLHNTRDALGRESLILERVQRDLSQTQCQKKETEQMYQIEQSKLKKYIAKQESVEERLSQLQSENMLLRQQLDDA 1059
Cdd:pfam14915 161 NSLENELHRTRDALREKTLLLESVQRDLSQAQCQKKELEHMYQNEQDKVNKYIGKQESLEERLAQLQSENMLLRQQLEDA 240
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 149363642 1060 HKKANSQEKTSSTIQDQFHSAAKNLQAESEKQILSLQEKNKELMDEYNHLKERMDQCEKEKAGR 1123
Cdd:pfam14915 241 QNKADAKEKTVIDIQDQFQDIVKKLQAESEKQVLLLEERNKELINECNHLKERLYQYEKEKAER 304
|
|
| DUF3496 |
pfam12001 |
Domain of unknown function (DUF3496); This presumed domain is functionally uncharacterized. ... |
1244-1354 |
2.17e-47 |
|
Domain of unknown function (DUF3496); This presumed domain is functionally uncharacterized. This domain is found in eukaryotes. This domain is about 110 amino acids in length.
Pssm-ID: 463425 [Multi-domain] Cd Length: 109 Bit Score: 164.84 E-value: 2.17e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1244 KTQMELTIKDLESEISRIKTSQADFNKTELERYKELYLEEVKVRESLSNELSRTNEMIAEVSTQLTVEKEQtrSRSLFTA 1323
Cdd:pfam12001 1 RSQMELRIKDLESELSKMKTSQEDSNKIELEKYKQLYLEELKVRKSLSNKLNKTNERLAEVSTKLLVEKQQ--NRSLLST 78
|
90 100 110
....*....|....*....|....*....|.
gi 149363642 1324 YATRPVLESPCVGNLNDSEGLNRKHIPRKKR 1354
Cdd:pfam12001 79 LTTRPVLESPCVGNLNNSLVLNRNFIPRENL 109
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
658-1303 |
4.37e-13 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 74.32 E-value: 4.37e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 658 QLTVKLKQMENMVSVLQNELSETKKTKLQLELQKIEWEKELYDLRLALKQENEEKrnADMLYNKDSEQLRIKEEEcgkvv 737
Cdd:TIGR02168 292 ALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKL--EELKEELESLEAELEELE----- 364
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 738 ETKQQLKWNLRRLVKELRTVRNNLDLVVQERNDAQKQLSE--------EQDARILQDQILTSKQKELEMARKKMNSEISH 809
Cdd:TIGR02168 365 AELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERlearlerlEDRRERLQQEIEELLKKLEEAELKELQAELEE 444
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 810 RHQKEKDLFHEDCMLQEEIALLRLEIDTIKNQNKQKEKKY------FEDIEAVKEKNDNLQKIIK--LNEETLTETILQY 881
Cdd:TIGR02168 445 LEEELEELQEELERLEEALEELREELEEAEQALDAAERELaqlqarLDSLERLQENLEGFSEGVKalLKNQSGLSGILGV 524
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 882 SGQLNNLTAE-------------NKILNSELENGKQNQERLEiEMESYRCRLAAAVRDCDQSQTARDLKL-----DFQRT 943
Cdd:TIGR02168 525 LSELISVDEGyeaaieaalggrlQAVVVENLNAAKKAIAFLK-QNELGRVTFLPLDSIKGTEIQGNDREIlknieGFLGV 603
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 944 RQEWVRLHDKMKVDMSG----------LQAKNEILseKLSNAESKINSLQIQLHNTRDAL-----GRESLILERvQRDLS 1008
Cdd:TIGR02168 604 AKDLVKFDPKLRKALSYllggvlvvddLDNALELA--KKLRPGYRIVTLDGDLVRPGGVItggsaKTNSSILER-RREIE 680
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1009 QTQCQKKETEQMYQIEQSKLKKYIAKQESVEERLSQLQSENMLLRQQLDDAHKKANSQEKTSSTIQDQFHSAAKNLqAES 1088
Cdd:TIGR02168 681 ELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKEL-TEL 759
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1089 EKQILSLQEKNKELMDEYNHLKERMDQCEKEKAGRKIDLTEAQETVPS-----RCLHLDAENEVLQLQQTLFSMKAIQKQ 1163
Cdd:TIGR02168 760 EAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDElraelTLLNEEAANLRERLESLERRIAATERR 839
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1164 CETLQKNKKQLKQEVVNLKSYMERnmLERGKAEWHK----LLIEERARKEIEEKLNEAILTLQKQAAVSHEQLVQLRE-- 1237
Cdd:TIGR02168 840 LEDLEEQIEELSEDIESLAAEIEE--LEELIEELESeleaLLNERASLEEALALLRSELEELSEELRELESKRSELRRel 917
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 149363642 1238 DNTTSIKTQMELTIKDLESEISRIKTSQADFNKTELERYKELYLEEVKVRESLSNELSRTNEMIAE 1303
Cdd:TIGR02168 918 EELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKE 983
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
649-1318 |
1.74e-12 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 72.40 E-value: 1.74e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 649 LKLKNNHCDQLTVKLKQMENMV-------SVLQNELSETKKTKLQLELQKIEWEKELYDLRLALKQENEEKRNADMLYNK 721
Cdd:TIGR02168 234 LEELREELEELQEELKEAEEELeeltaelQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLAN 313
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 722 DSEQLRIKEEECGKVVETKQQLKWNLRRLVKELRTVRNNLDLvVQERNDAQKQLSEEQDARI--LQDQILT--SKQKELE 797
Cdd:TIGR02168 314 LERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELES-LEAELEELEAELEELESRLeeLEEQLETlrSKVAQLE 392
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 798 MARKKMNSEISHRHQKEKDLFHEDCMLQEEI-----ALLRLEIDTIKNQNKQKEKKYFEDIEAVKEKNDNLQKIIKLNEE 872
Cdd:TIGR02168 393 LQIASLNNEIERLEARLERLEDRRERLQQEIeellkKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEE 472
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 873 tLTETILQYSGQLNNLTAENKILNSELENG----------KQNQERLE---------IEMES-YRCRLAAAVRD------ 926
Cdd:TIGR02168 473 -AEQALDAAERELAQLQARLDSLERLQENLegfsegvkalLKNQSGLSgilgvlselISVDEgYEAAIEAALGGrlqavv 551
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 927 CDQSQTARD---------------LKLD--------------------FQRTRQEWVRLHDKMKVDMSG----------L 961
Cdd:TIGR02168 552 VENLNAAKKaiaflkqnelgrvtfLPLDsikgteiqgndreilkniegFLGVAKDLVKFDPKLRKALSYllggvlvvddL 631
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 962 QAKNEILseKLSNAESKINSLQIQLHNTRDAL-----GRESLILERvQRDLSQTQCQKKETEQMYQIEQSKLKKYIAKQE 1036
Cdd:TIGR02168 632 DNALELA--KKLRPGYRIVTLDGDLVRPGGVItggsaKTNSSILER-RREIEELEEKIEELEEKIAELEKALAELRKELE 708
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1037 SVEERLSQLQSENMLLRQQLDDAHKKANSQEKTSSTIQDQFHSAAKNLqAESEKQILSLQEKNKELMDEYNHLKERMDQC 1116
Cdd:TIGR02168 709 ELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKEL-TELEAEIEELEERLEEAEEELAEAEAEIEEL 787
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1117 EKEKAGRKIDLTEAQETVPS-----RCLHLDAENEVLQLQQTLFSMKAIQKQCETLQKNKKQLKQEVVNLKSYMERnmle 1191
Cdd:TIGR02168 788 EAQIEQLKEELKALREALDElraelTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEE---- 863
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1192 rgkaewhklliEERARKEIEEKLNEailtLQKQAAVSHEQLVQLREDNTTSIKTQ--MELTIKDLESEISRIKTSQADFN 1269
Cdd:TIGR02168 864 -----------LEELIEELESELEA----LLNERASLEEALALLRSELEELSEELreLESKRSELRRELEELREKLAQLE 928
|
730 740 750 760
....*....|....*....|....*....|....*....|....*....
gi 149363642 1270 ktelERYKELYLEEVKVRESLSNELSRTNEMIAEVSTQLTVEKEQTRSR 1318
Cdd:TIGR02168 929 ----LRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRR 973
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
466-1279 |
1.97e-12 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 72.40 E-value: 1.97e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 466 YKSLKPKLENLsslppdsDRTSEVYLHEELQQDMQKFKNEVNTLEEEFLALKKEDVQLHKDVEEEMEKHRSNSTELSGTL 545
Cdd:TIGR02168 215 YKELKAELREL-------ELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQ 287
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 546 TDGTTVGNDDDGLNQQI----PRKENGEHDRPADKTSNEKNEVKNQIYpEADFADSMEPSEIASEDCElshsvyeNFMLL 621
Cdd:TIGR02168 288 KELYALANEISRLEQQKqilrERLANLERQLEELEAQLEELESKLDEL-AEELAELEEKLEELKEELE-------SLEAE 359
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 622 IEQLRMEYKDSASLPRIQDtfclcEHLLKLKNnhcdqltvKLKQMENMVSVLQNELSETKKTKLQLELQkiewekelydl 701
Cdd:TIGR02168 360 LEELEAELEELESRLEELE-----EQLETLRS--------KVAQLELQIASLNNEIERLEARLERLEDR----------- 415
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 702 rlalkQENEEKRNADMLYNKDSEQLRIKEEECGKVVETKQQLKWNLRRLVKELRTVRNNLDLVVQERNDAQKQLSEEQDA 781
Cdd:TIGR02168 416 -----RERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQAR 490
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 782 RILQDQILTSKQKELEMARKKMN--SEISHRHQKEKDLFHEDCMLQEEI-ALLRLEIDTIknqNKQKEKKYFEDIEAVKE 858
Cdd:TIGR02168 491 LDSLERLQENLEGFSEGVKALLKnqSGLSGILGVLSELISVDEGYEAAIeAALGGRLQAV---VVENLNAAKKAIAFLKQ 567
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 859 KNDNLQKIIKLNeeTLTETILQYSGqLNNLTAENKILNSELENGKQNqERLEIEMESyrcrLAAAVRDCDQSQTARDLK- 937
Cdd:TIGR02168 568 NELGRVTFLPLD--SIKGTEIQGND-REILKNIEGFLGVAKDLVKFD-PKLRKALSY----LLGGVLVVDDLDNALELAk 639
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 938 ----------LDFQRTRQEWVRLHDKMKVDMSGLQAKNEI--LSEKLSNAESKINSLQIQLHNTRDALGRESLILERVQR 1005
Cdd:TIGR02168 640 klrpgyrivtLDGDLVRPGGVITGGSAKTNSSILERRREIeeLEEKIEELEEKIAELEKALAELRKELEELEEELEQLRK 719
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1006 DLSQTQCQKKETEQMYQIEQSKLKKYIAKQESVEERLSQLQSENMLLRQQLDDAHKKANSQEKTSSTIQDQFHSAAKNLQ 1085
Cdd:TIGR02168 720 ELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELK 799
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1086 AeSEKQILSLQEKNKELMDEYNHLKERMDQCEKEKAGRKIDLTEAQETvpSRCLHLDAENEVLQLQQTLFSMKAIQKQCE 1165
Cdd:TIGR02168 800 A-LREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQ--IEELSEDIESLAAEIEELEELIEELESELE 876
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1166 TLQKNKKQLKQEVVNLKSYMERNMLERGKAEwHKLLIEERARKEIEEKLNEAILTLQKQAAVSHEQLVQLREDNTTSIKT 1245
Cdd:TIGR02168 877 ALLNERASLEEALALLRSELEELSEELRELE-SKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEE 955
|
810 820 830 840
....*....|....*....|....*....|....*....|...
gi 149363642 1246 QMELT------IKDLESEISRIKTSQADF---NKTELERYKEL 1279
Cdd:TIGR02168 956 AEALEnkieddEEEARRRLKRLENKIKELgpvNLAAIEEYEEL 998
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
730-1120 |
2.23e-12 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 72.02 E-value: 2.23e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 730 EEECGKVVETKQQLKWNLRRLVKELRTVRNNLDLVVQERNDAQKQLSE-EQDARILQDQILTSKQ--KELEMARKKMNSE 806
Cdd:TIGR02169 673 PAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEiEKEIEQLEQEEEKLKErlEELEEDLSSLEQE 752
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 807 ISHRHQKEKDLFHEDCMLQEEIALLRLEIDTIKNQNKQkekkyfEDIEAVKEKNDNLQKIIKLNEETLTETilqySGQLN 886
Cdd:TIGR02169 753 IENVKSELKELEARIEELEEDLHKLEEALNDLEARLSH------SRIPEIQAELSKLEEEVSRIEARLREI----EQKLN 822
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 887 NLTAENKILNSELENGKQNQERLEIEMESYRCRLAAAVRDcdqsqtARDLKLDFQRTRQEWVRLHDKMKvdmsGLQAKNE 966
Cdd:TIGR02169 823 RLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGK------KEELEEELEELEAALRDLESRLG----DLKKERD 892
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 967 ILSEKLSNAESKINSLQIQLHNTRDALGRESLILERVQRDLSQTQCQKKEtEQMYQIEQSKLKKYIAKQESVEERLSQLQ 1046
Cdd:TIGR02169 893 ELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGE-DEEIPEEELSLEDVQAELQRVEEEIRALE 971
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 149363642 1047 SENMLLRQQLDdahkkansqektsstiqdqfhsaaknlqaESEKQILSLQEKNKELMDEYNHLKERMDQCEKEK 1120
Cdd:TIGR02169 972 PVNMLAIQEYE-----------------------------EVLKRLDELKEKRAKLEEERKAILERIEEYEKKK 1016
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
762-1134 |
1.66e-11 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 69.32 E-value: 1.66e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 762 DLVVQERNDAQKQLSEEQDARILQDQILTSKQKELEMARKKMNSEISHRHQKEKDLFHEDCMLQEEIALLRLEIDTIKNQ 841
Cdd:TIGR02168 669 NSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEER 748
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 842 NKQKEkkyFEDIEAVKEKNDNLQKIIKLNE---------ETLTETILQYSGQLNNLTAENKILNSELENGKQNQERLEIE 912
Cdd:TIGR02168 749 IAQLS---KELTELEAEIEELEERLEEAEEelaeaeaeiEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRER 825
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 913 MESYRCRLAAAvrdcdqsqtardlkldfQRTRQEWVRLHDKMKVDMSGLQAKNEILSEKLSNAESKINSLQIQLHNTRDA 992
Cdd:TIGR02168 826 LESLERRIAAT-----------------ERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEA 888
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 993 LGRESLILERVQRDLSQTQCQKKETEQMYQIEQSKLKKYIAKQESVEERLSQLQSenmllrqqlddahkKANSQEKTSST 1072
Cdd:TIGR02168 889 LALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQE--------------RLSEEYSLTLE 954
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 149363642 1073 IQDQFHSAAKNLQAESEKQILSLQEKNKEL-------MDEYNHLKERMDQCEKEKAgrkiDLTEAQETV 1134
Cdd:TIGR02168 955 EAEALENKIEDDEEEARRRLKRLENKIKELgpvnlaaIEEYEELKERYDFLTAQKE----DLTEAKETL 1019
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
746-1065 |
2.77e-08 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 58.91 E-value: 2.77e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 746 NLRRL---VKELRTVRNNLDLVVQ--ERNDAQKQLSEEQDARILQDQI--LTSKQKELEMARKKMNSEIsHRHQKEKDlf 818
Cdd:TIGR02168 187 NLDRLediLNELERQLKSLERQAEkaERYKELKAELRELELALLVLRLeeLREELEELQEELKEAEEEL-EELTAELQ-- 263
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 819 hedcMLQEEIALLRLEIDTIKNQNKQKEKKYFEDIEAVKEKNDNLQkIIKLNEETLTETILQYSGQLNNLTAENKILNSE 898
Cdd:TIGR02168 264 ----ELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQ-ILRERLANLERQLEELEAQLEELESKLDELAEE 338
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 899 LENGKQNQERLEIEMESYRCRLAAavrdcdqsqtARDLKLDFQRTRQEWVRLHDKMKVDMSGLQAKNEILSEKLSNAESK 978
Cdd:TIGR02168 339 LAELEEKLEELKEELESLEAELEE----------LEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEAR 408
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 979 INSLQIQLHNTRDALGRESLILERVQRDLSQTQCQKKETEqmyqieqskLKKYIAKQESVEERLSQLQSENMLLRQQLDD 1058
Cdd:TIGR02168 409 LERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEE---------LEELQEELERLEEALEELREELEEAEQALDA 479
|
....*..
gi 149363642 1059 AHKKANS 1065
Cdd:TIGR02168 480 AERELAQ 486
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
661-1285 |
2.84e-08 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 58.49 E-value: 2.84e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 661 VKLKQMENMVSVLQNELSETKKTKLQLELQKIEWEKELYDLRLALKQENEEKRNADML------YNKDSEQLRIK----E 730
Cdd:TIGR04523 145 TEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELLlsnlkkKIQKNKSLESQiselK 224
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 731 EECGKVVETKQQLKWNLRRLVKELRTVRNNLDLVVQERNDAQKQLSEEQDARILQDQILTSKQKELemarKKMNSEISH- 809
Cdd:TIGR04523 225 KQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQL----NQLKSEISDl 300
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 810 RHQKEKDLFHEdcmlqeeiallrleidtiknqnkqkekkYFEDIEAVKEKNDNLQKIIKLNEET---LTETILQYSGQLN 886
Cdd:TIGR04523 301 NNQKEQDWNKE----------------------------LKSELKNQEKKLEEIQNQISQNNKIisqLNEQISQLKKELT 352
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 887 NLTAENKILNSELENGKQNQERLEIEMESYRCRLAaavrdcDQSQTARDLKLDFQRTRQEWVRLHDKMKVdmsgLQAKNE 966
Cdd:TIGR04523 353 NSESENSEKQRELEEKQNEIEKLKKENQSYKQEIK------NLESQINDLESKIQNQEKLNQQKDEQIKK----LQQEKE 422
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 967 ILSEKLSNAESKINSLQIQLHNTRDALGRESLILERVQRDLSQTQCQKKETEQMYQIEQSKLKKYIAKQESVEERLSQLQ 1046
Cdd:TIGR04523 423 LLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLN 502
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1047 SENMLLRQQLDDAHKKAnsqektsstiqdqfhSAAKNLQAESEKQILSLQEKNKELMDEYNHLKERMDQCEKEKAGRKID 1126
Cdd:TIGR04523 503 EEKKELEEKVKDLTKKI---------------SSLKEKIEKLESEKKEKESKISDLEDELNKDDFELKKENLEKEIDEKN 567
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1127 lteaqetvpsrclhldaeNEVLQLQQTLFSMKAIQKQcetLQKNKKQLKQEVVNLKSYMERNMLERGKAEWHKLLIEERA 1206
Cdd:TIGR04523 568 ------------------KEIEELKQTQKSLKKKQEE---KQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKEN 626
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1207 RK--EIEEKLNEAILTLQKQAAVSHEQLvqlreDNTTSIKTQMELTIKDLESEISRIKTSQADFNKTELERYKELYLEEV 1284
Cdd:TIGR04523 627 EKlsSIIKNIKSKKNKLKQEVKQIKETI-----KEIRNKWPEIIKKIKESKTKIDDIIELMKDWLKELSLHYKKYITRMI 701
|
.
gi 149363642 1285 K 1285
Cdd:TIGR04523 702 R 702
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
765-1308 |
7.56e-08 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 57.44 E-value: 7.56e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 765 VQERNDAQKQLSEEQDARILQDQI-LTSKQKELEMARKKMNSEISHRHQKEKDLFHEdcmLQEEIallrleidtiknqnk 843
Cdd:pfam15921 90 LQRRLNESNELHEKQKFYLRQSVIdLQTKLQEMQMERDAMADIRRRESQSQEDLRNQ---LQNTV--------------- 151
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 844 qkekkyfEDIEAVKEKNDNLQKIIKLNEETLTETILQYSGQLNNLtaENKILNSELENGKQNQERLEIEMESYRcRLAAA 923
Cdd:pfam15921 152 -------HELEAAKCLKEDMLEDSNTQIEQLRKMMLSHEGVLQEI--RSILVDFEEASGKKIYEHDSMSTMHFR-SLGSA 221
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 924 VrdcdqSQTARDLKLDFQRTRQEWVRLHDKMKVDMSGLQAKNEIL----------------------SEKLSNAESKINS 981
Cdd:pfam15921 222 I-----SKILRELDTEISYLKGRIFPVEDQLEALKSESQNKIELLlqqhqdrieqliseheveitglTEKASSARSQANS 296
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 982 LQIQLHntrdalgresLILERVQRDLSQTQCQKKETEQMYQIEQSKLKKyiaKQESVEERLSQLQSENMLlrqqlddahk 1061
Cdd:pfam15921 297 IQSQLE----------IIQEQARNQNSMYMRQLSDLESTVSQLRSELRE---AKRMYEDKIEELEKQLVL---------- 353
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1062 kANSQEKTSSTIQDQFHSAAKNLQAESEKQILSLQEKNKELMDEynhlKERMDQCEKEKAGRKIDLTEAQETVPSRCLhl 1141
Cdd:pfam15921 354 -ANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELSLE----KEQNKRLWDRDTGNSITIDHLRRELDDRNM-- 426
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1142 daenEVLQLQQTLFSMKA-----IQKQCETLQKNKKQLkQEVVNLKSYMERNmlergkaewhklliEERARKEIEEklne 1216
Cdd:pfam15921 427 ----EVQRLEALLKAMKSecqgqMERQMAAIQGKNESL-EKVSSLTAQLEST--------------KEMLRKVVEE---- 483
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1217 aiLTLQKQAAVSHEQLVQlreDNTTSIKtQMELTIKDLESEISRIKtSQADFNKTELERYK--ELYLEEVKVR-ESLSNE 1293
Cdd:pfam15921 484 --LTAKKMTLESSERTVS---DLTASLQ-EKERAIEATNAEITKLR-SRVDLKLQELQHLKneGDHLRNVQTEcEALKLQ 556
|
570
....*....|....*
gi 149363642 1294 LSRTNEMIAEVSTQL 1308
Cdd:pfam15921 557 MAEKDKVIEILRQQI 571
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
976-1313 |
8.32e-08 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 56.99 E-value: 8.32e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 976 ESKINSLQIQ---------LHNTRDALGRESLI--LERVQRDLSQTQCQKKETEQMYQIEQSKLKKYIAKQESVEERLSQ 1044
Cdd:TIGR02168 199 ERQLKSLERQaekaerykeLKAELRELELALLVlrLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSE 278
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1045 LQSENMLLRQQLDDAHKKANSQEKTSSTIQDQFHSAAKNlQAESEKQILSLQEKNKELMDEYNHLKERMDQCEKEKAGRK 1124
Cdd:TIGR02168 279 LEEEIEELQKELYALANEISRLEQQKQILRERLANLERQ-LEELEAQLEELESKLDELAEELAELEEKLEELKEELESLE 357
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1125 IDLTEAQETVPSRCLHLDAENEVLQ-----LQQTLFSMKAIQKQCETLQKNKKQLKQEVVNLKSYMERNMLERGKAEWHK 1199
Cdd:TIGR02168 358 AELEELEAELEELESRLEELEEQLEtlrskVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKE 437
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1200 LLIEERARKEIEEKLNEAILTLQKQAAVSHEQLVQLREDnttsiktqmeltIKDLESEISRIKtSQADFNKTELERYKEL 1279
Cdd:TIGR02168 438 LQAELEELEEELEELQEELERLEEALEELREELEEAEQA------------LDAAERELAQLQ-ARLDSLERLQENLEGF 504
|
330 340 350
....*....|....*....|....*....|....
gi 149363642 1280 YlEEVKvreSLSNELSRTNEMIAEVSTQLTVEKE 1313
Cdd:TIGR02168 505 S-EGVK---ALLKNQSGLSGILGVLSELISVDEG 534
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
890-1234 |
1.58e-07 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 56.10 E-value: 1.58e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 890 AENKilnseLENGKQNQERLEI---EMESYRCRLAaavRDCDQSQTARDLKLDFQRTRQEWVRLHDK--------MKVDM 958
Cdd:COG1196 177 AERK-----LEATEENLERLEDilgELERQLEPLE---RQAEKAERYRELKEELKELEAELLLLKLReleaeleeLEAEL 248
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 959 SGLQAKNEILSEKLSNAESKINSLQIQLHNTRDAL----GRESLI---LERVQRDLSQTQCQKKETEQMYQIEQSKLKKY 1031
Cdd:COG1196 249 EELEAELEELEAELAELEAELEELRLELEELELELeeaqAEEYELlaeLARLEQDIARLEERRRELEERLEELEEELAEL 328
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1032 IAKQESVEERLSQLQSENMLLRQQLDDAHKKANSQEKTSSTIQDQFHSAAKNLQAEsEKQILSLQEKNKELMDEYNHLKE 1111
Cdd:COG1196 329 EEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEEL-AEELLEALRAAAELAAQLEELEE 407
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1112 RMDQCEKEKAGRKIDLTEAQETVpsrclhLDAENEVLQLQQTLfsmKAIQKQCETLQKNKKQLKQEVVNLKsymernmle 1191
Cdd:COG1196 408 AEEALLERLERLEEELEELEEAL------AELEEEEEEEEEAL---EEAAEEEAELEEEEEALLELLAELL--------- 469
|
330 340 350 360
....*....|....*....|....*....|....*....|...
gi 149363642 1192 rgkaEWHKLLIEERARKEIEEKLNEAILTLQKQAAVSHEQLVQ 1234
Cdd:COG1196 470 ----EEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLE 508
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
658-1318 |
2.14e-07 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 55.83 E-value: 2.14e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 658 QLTVKLKQMENMVSVLQNELSETKKTKLQLELQKIEWEKELYDLRLALKQEN-EEKRNADmlyNKDSEQLRIKEEECGKV 736
Cdd:TIGR02168 217 ELKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKlEELRLEV---SELEEEIEELQKELYAL 293
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 737 VETKQQLKWNLRRLVKELRTVRNNLDLVVQERNDAQKQLSEEQDARILQDQILTSKQKELEMAR---KKMNSEISHRHQK 813
Cdd:TIGR02168 294 ANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEaelEELEAELEELESR 373
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 814 EKDLFHEDCMLQEEIALLRLEIDTIKNQNKQKEkkyfEDIEAVKEKNDNLQKIIKLNEETLTETILQYSG--------QL 885
Cdd:TIGR02168 374 LEELEEQLETLRSKVAQLELQIASLNNEIERLE----ARLERLEDRRERLQQEIEELLKKLEEAELKELQaeleeleeEL 449
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 886 NNLTAENKILNSELENGKQNQERLEIEMESYRCRLAAAVRDCDQSQTARDLKLDFQRTRQEWV-----------RLHDKM 954
Cdd:TIGR02168 450 EELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLknqsglsgilgVLSELI 529
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 955 KVDMSGLQAKNEILSEKLSNAESKINSLQIQL--HNTRDALGRESLILERVQRDlsqtqcQKKETEQMYQIEQSKLKKYI 1032
Cdd:TIGR02168 530 SVDEGYEAAIEAALGGRLQAVVVENLNAAKKAiaFLKQNELGRVTFLPLDSIKG------TEIQGNDREILKNIEGFLGV 603
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1033 AKqeSVEERLSQLQS--ENML--------LRQQLDDAHKkaNSQEKTSSTIQDQFHSAAKNLQAESEKQILSLQEKNKEL 1102
Cdd:TIGR02168 604 AK--DLVKFDPKLRKalSYLLggvlvvddLDNALELAKK--LRPGYRIVTLDGDLVRPGGVITGGSAKTNSSILERRREI 679
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1103 mdeyNHLKERMDQCEKEKAGRKIDLTEAQETvpsrclHLDAENEVLQLQQTLFSM-----------KAIQKQCETLQKNK 1171
Cdd:TIGR02168 680 ----EELEEKIEELEEKIAELEKALAELRKE------LEELEEELEQLRKELEELsrqisalrkdlARLEAEVEQLEERI 749
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1172 KQLKQEVVNLKSYMERNMLERGKAEWHKLLIEE-------------RARKEIEEKLNE--AILTLQKQAAVSHEQLVQLR 1236
Cdd:TIGR02168 750 AQLSKELTELEAEIEELEERLEEAEEELAEAEAeieeleaqieqlkEELKALREALDElrAELTLLNEEAANLRERLESL 829
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1237 EDNTTSIKTQME---LTIKDLESEISRIKTSQADF--NKTELERYKELYLEEVKVRESLSNELSRtnEMIAEVSTQLTVE 1311
Cdd:TIGR02168 830 ERRIAATERRLEdleEQIEELSEDIESLAAEIEELeeLIEELESELEALLNERASLEEALALLRS--ELEELSEELRELE 907
|
....*..
gi 149363642 1312 KEQTRSR 1318
Cdd:TIGR02168 908 SKRSELR 914
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
747-1238 |
5.09e-07 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 54.54 E-value: 5.09e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 747 LRRLVKELRTVRNNLDLVVQERNDAQKQLSE-EQDARILQDQILTSKQKELEMARKkmnsEISHRHQKEKDLFHEDCMLQ 825
Cdd:COG4913 290 LELLEAELEELRAELARLEAELERLEARLDAlREELDELEAQIRGNGGDRLEQLER----EIERLERELEERERRRARLE 365
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 826 EEIALLRLEIDTIKNQnkqkekkyFEDI-EAVKEKNDNLQKIIKLNEETLTETIlqysGQLNNLTAENKILNSELENGKQ 904
Cdd:COG4913 366 ALLAALGLPLPASAEE--------FAALrAEAAALLEALEEELEALEEALAEAE----AALRDLRRELRELEAEIASLER 433
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 905 NQERLEIEMESYRCRLAAA----------------VRDCDQS-QTA-----RDLKLD-------FQRTRqEWV-RLHDKM 954
Cdd:COG4913 434 RKSNIPARLLALRDALAEAlgldeaelpfvgelieVRPEEERwRGAiervlGGFALTllvppehYAAAL-RWVnRLHLRG 512
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 955 KVDMSGLQAKNEI----------LSEKLSNAESKI-NSLQIQLHNTRDALGRESL-ILERVQRDLSQTqCQKKETEQMYQ 1022
Cdd:COG4913 513 RLVYERVRTGLPDperprldpdsLAGKLDFKPHPFrAWLEAELGRRFDYVCVDSPeELRRHPRAITRA-GQVKGNGTRHE 591
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1023 IeqsKLKKYIAKQ----ESVEERLSQLQSENMLLRQQLDDAHKKANSQEKTSSTIQDQFHSAAKNLQ-AESEKQILSLQE 1097
Cdd:COG4913 592 K---DDRRRIRSRyvlgFDNRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEySWDEIDVASAER 668
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1098 KNKELMDEYNHLKERMDqcekekagrkiDLTEAQETVpsrclhLDAENEVLQLQQTLfsmKAIQKQCETLQKNKKQLKQE 1177
Cdd:COG4913 669 EIAELEAELERLDASSD-----------DLAALEEQL------EELEAELEELEEEL---DELKGEIGRLEKELEQAEEE 728
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 149363642 1178 VVNLKSYMERnmLERGKAEWHKLLIEER--------ARKEIEEKLNEAILTLQKQAAVSHEQLVQLRED 1238
Cdd:COG4913 729 LDELQDRLEA--AEDLARLELRALLEERfaaalgdaVERELRENLEERIDALRARLNRAEEELERAMRA 795
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
721-1314 |
5.40e-07 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 54.34 E-value: 5.40e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 721 KDSEQLRIKEEECGKVVETKQQLKWNLRRLVKELRTVRNNLDLVVQERNDAQKQLSEEQDARILQDQILTSKQ----KEL 796
Cdd:pfam05483 219 EDHEKIQHLEEEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKANQLEEKTKLQDENLKELIEKKdhltKEL 298
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 797 EMARKKMNSEISHRHQKEKDLfhedCMLQEEIALLRLEIDTIKNQNKQKEKKYFEDIEAVKEKNDNLQKIIKLNEETLTE 876
Cdd:pfam05483 299 EDIKMSLQRSMSTQKALEEDL----QIATKTICQLTEEKEAQMEELNKAKAAHSFVVTEFEATTCSLEELLRTEQQRLEK 374
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 877 TilqySGQLNNLTAENKILNSELENGKQNQERLEIEMESYRCRLAaavrdcdQSQTARDLKLDFQRTRQEwvrlhdkmkv 956
Cdd:pfam05483 375 N----EDQLKIITMELQKKSSELEEMTKFKNNKEVELEELKKILA-------EDEKLLDEKKQFEKIAEE---------- 433
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 957 dmsgLQAKNEILSEKLSNAESKINSLQIQLHNTRdalgreslilervqrdlSQTQCQKKETEQMyqieQSKLKKYIAKQE 1036
Cdd:pfam05483 434 ----LKGKEQELIFLLQAREKEIHDLEIQLTAIK-----------------TSEEHYLKEVEDL----KTELEKEKLKNI 488
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1037 SVEERLSQLQSENMLLRQQLDDAHKKANSQEKTSSTIQDQfhsaaknlQAESEKQILSLQEKNKELMDEYNHLKERMDQc 1116
Cdd:pfam05483 489 ELTAHCDKLLLENKELTQEASDMTLELKKHQEDIINCKKQ--------EERMLKQIENLEEKEMNLRDELESVREEFIQ- 559
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1117 EKEKAGRKIDLTEAQetvpSRCLHLDAENEVLQLQQTLFSMKAIQKQCETLQKNKKQLKQE--VVNLKSYMERNMLERGK 1194
Cdd:pfam05483 560 KGDEVKCKLDKSEEN----ARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQEnkALKKKGSAENKQLNAYE 635
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1195 AEWHKLLIEERARKEieeKLNEAILTLQKQ---AAVSHEQLVQLREDNTT----SIKTQMELTIK---DLESEISRIKTS 1264
Cdd:pfam05483 636 IKVNKLELELASAKQ---KFEEIIDNYQKEiedKKISEEKLLEEVEKAKAiadeAVKLQKEIDKRcqhKIAEMVALMEKH 712
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....*.
gi 149363642 1265 QADFNKTELERYKELYL------EEVKVRESLSNELSRTNEMIAEVSTQLTVEKEQ 1314
Cdd:pfam05483 713 KHQYDKIIEERDSELGLyknkeqEQSSAKAALEIELSNIKAELLSLKKQLEIEKEE 768
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
667-1205 |
8.69e-07 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 53.69 E-value: 8.69e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 667 ENMVSVLQNELSEtkktklQLELQKIEWEKELYDLRLALkqENEEKRNADMLYNKDS-EQLRIKEEECGKVVETKQQLKW 745
Cdd:pfam12128 414 EDDLQALESELRE------QLEAGKLEFNEEEYRLKSRL--GELKLRLNQATATPELlLQLENFDERIERAREEQEAANA 485
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 746 NLRRLVKELRTVRNNLDLVVQERNDAQKQLSEEQDA-RILQDQILTSKQKELEMARKK-----------MNSEISHRHQK 813
Cdd:pfam12128 486 EVERLQSELRQARKRRDQASEALRQASRRLEERQSAlDELELQLFPQAGTLLHFLRKEapdweqsigkvISPELLHRTDL 565
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 814 EKDLFHEDCMLQEEIALLRLEIDTIKNQNkqkekkYFEDIEAVKEKNDNLQKIIKLNEET---LTETILQYSGQLNNLTA 890
Cdd:pfam12128 566 DPEVWDGSVGGELNLYGVKLDLKRIDVPE------WAASEEELRERLDKAEEALQSAREKqaaAEEQLVQANGELEKASR 639
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 891 ENKILNSELENGKQNQERLEIEMESYRCRLaaavrdcdQSQTARDLKLDFQRTRQewvrLHDKMKVDMSGLQA-KNEILS 969
Cdd:pfam12128 640 EETFARTALKNARLDLRRLFDEKQSEKDKK--------NKALAERKDSANERLNS----LEAQLKQLDKKHQAwLEEQKE 707
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 970 EKLSNAESKINSLQIQLHNTRDALGR--ESLILERVQRDLSQTQCQKketeqmyqieqsKLKKYIAKQESVEERLSQLQS 1047
Cdd:pfam12128 708 QKREARTEKQAYWQVVEGALDAQLALlkAAIAARRSGAKAELKALET------------WYKRDLASLGVDPDVIAKLKR 775
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1048 ENMLLRQQLDDAHKKANSQEKTSSTIQDQFHSAAKNLQAESEKQILSLQEKNKELMDEYNHLKERMDQCEKE-KAGRK-- 1124
Cdd:pfam12128 776 EIRTLERKIERIAVRRQEVLRYFDWYQETWLQRRPRLATQLSNIERAISELQQQLARLIADTKLRRAKLEMErKASEKqq 855
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1125 IDLTEAQETVPSRC-----LHLDAENEVLQLQQTlFSMKAIQKQCETLQKNKKQLKQEVVNLKSYMERNMLERGKAEWHK 1199
Cdd:pfam12128 856 VRLSENLRGLRCEMsklatLKEDANSEQAQGSIG-ERLAQLEDLKLKRDYLSESVKKYVEHFKNVIADHSGSGLAETWES 934
|
....*.
gi 149363642 1200 LLIEER 1205
Cdd:pfam12128 935 LREEDH 940
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
676-1262 |
1.57e-06 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 53.02 E-value: 1.57e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 676 ELSETKKtKLQLELQKIEWEkelyDLRLALKQENEEKRNADMLYNKDSEQLRIKEEEcgkvvetkqqlkwnlrrlVKELR 755
Cdd:COG1196 217 ELKEELK-ELEAELLLLKLR----ELEAELEELEAELEELEAELEELEAELAELEAE------------------LEELR 273
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 756 TVRNNLDLVVQERNDAQKQLSEEQDARILQDQILTSKQKELEMARKKMNSEISHRHQKEKDlfhedcmLQEEIALLRLEI 835
Cdd:COG1196 274 LELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEE-------LEEELEELEEEL 346
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 836 DTIKNQNKQKEKKYFEDIEAVKEKNDNLQKIIKLnEETLTETILQYSGQLNNLTAENKILNSELENGKQNQERLEIEMES 915
Cdd:COG1196 347 EEAEEELEEAEAELAEAEEALLEAEAELAEAEEE-LEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEE 425
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 916 yrcRLAAAVRDCDQSQTARDLKLDFQRTRQEWVRLHDKMKVDMSGLQAKNEILSEKLSNAESKINSLQIQLHNTRDALGR 995
Cdd:COG1196 426 ---LEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEAD 502
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 996 ESLILERVQRdLSQTQCQKKETEQMYQIEQSKLKKYIAKQESVEERLSQLQSENMLLRQQLDDAHKKANSQEKT---SST 1072
Cdd:COG1196 503 YEGFLEGVKA-ALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATflpLDK 581
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1073 IQDQFHSAAKNLQAESEKQILSLQEKNKELMDEY----NHLKERMDQCEKEKAGRKIDLTEAQETVPSRclhLDAENEVL 1148
Cdd:COG1196 582 IRARAALAAALARGAIGAAVDLVASDLREADARYyvlgDTLLGRTLVAARLEAALRRAVTLAGRLREVT---LEGEGGSA 658
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1149 QLQQTLFSMKAIQKQCETLQKNKKQLKQEVVNLKSYMERNMLERGKAEwhkLLIEERARKEIEEKLNEAILTLQKQAAVS 1228
Cdd:COG1196 659 GGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEE---RELAEAEEERLEEELEEEALEEQLEAERE 735
|
570 580 590
....*....|....*....|....*....|....*...
gi 149363642 1229 HEQLVQLREDNTTSI----KTQMELTIKDLESEISRIK 1262
Cdd:COG1196 736 ELLEELLEEEELLEEealeELPEPPDLEELERELERLE 773
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
649-1314 |
4.50e-06 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 51.51 E-value: 4.50e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 649 LKLKNNHCDQLTVKLKQMENMVSVLQNELSETKKTKLQLELQKIEWEKELYDLRLALKQENEEKR---NADMLYNKDSEQ 725
Cdd:pfam02463 215 LKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKekkLQEEELKLLAKE 294
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 726 LRIKEEECGKVVETKQQLKWNLRRLVKELRTVRNNLDLVVQERNDAQKQLSEEQDARILQDQILTSKQKELEMARKKMNS 805
Cdd:pfam02463 295 EEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEE 374
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 806 EISHRHQKEKDLFHEDCMLQEEIALLRLEIDTIKNQNKQKekkyfediEAVKEKNDNLQKIIKLNEETLTETILQYSGQL 885
Cdd:pfam02463 375 LLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELA--------RQLEDLLKEEKKEELEILEEEEESIELKQGKL 446
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 886 NNLTAENKILNSELENGKQNQERLEIEMESYRCRLAAAVRDCDQSqtarDLKLDFQRTRQEWVRLHDKMKVDMSGLQAKN 965
Cdd:pfam02463 447 TEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLS----RQKLEERSQKESKARSGLKVLLALIKDGVGG 522
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 966 EILSEKLSNAE-SKINSLQIQLHNTRDALGRESLILERVQRDLSQTQCQKKETEQMYQIEQSKLKKYIAKQESVEERLSQ 1044
Cdd:pfam02463 523 RIISAHGRLGDlGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPI 602
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1045 LQSENMLLRQQLDDAHKKANS--QEKTSSTIQDQFHSAAKNLQAESEKQILSLQEKNKELMDEYNHLKERMDQCEKEKAG 1122
Cdd:pfam02463 603 LNLAQLDKATLEADEDDKRAKvvEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQ 682
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1123 RKIDLTEAQETVPSRCLHLDAENEVLQLQQTLFSMKAIQKQCETLQKNKKQLKQEVVNLKSYMERNMLERGKAEWHKLLI 1202
Cdd:pfam02463 683 EKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEK 762
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1203 EERARKEIE-EKLNEAILTLQKQAAVSHEQLVQLREDNTTSIKTQMELTIKDLESEISRIKTSQADFNKTELERYKELYL 1281
Cdd:pfam02463 763 EEEKSELSLkEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALEL 842
|
650 660 670
....*....|....*....|....*....|...
gi 149363642 1282 EEVKVRESLSNELSRTNEMIAEVSTQLTVEKEQ 1314
Cdd:pfam02463 843 KEEQKLEKLAEEELERLEEEITKEELLQELLLK 875
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
657-1181 |
4.97e-06 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 51.48 E-value: 4.97e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 657 DQLTVKLKQMENMVSVLQNELSETKKTKLQLELQKIEWEKELYDLRLALKQENEEKRNADMLYNKDSEQLRIKEEECGKV 736
Cdd:COG1196 249 EELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAEL 328
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 737 VETKQQLKWNLRRLVKELRTVRNNLDLVVQERNDAQKQLSEEQDARI-LQDQILTSKQKELEMARKKMN--SEISHRHQK 813
Cdd:COG1196 329 EEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAeAEEELEELAEELLEALRAAAElaAQLEELEEA 408
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 814 EKDLFHEDCMLQEEIALLRLEIDTIKNQNKQKEKKYFEDIEAVKEKNDNLQKIIKLNEETLTETILQYSgQLNNLTAENK 893
Cdd:COG1196 409 EEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEA-ALAELLEELA 487
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 894 ILNSELENGKQNQERLEIEMESYRCRLAAAVRDCDQSQTARDLKLDF-----QRTRQEWVRLHDKMKVDMSGLQAKNEIL 968
Cdd:COG1196 488 EAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAayeaaLEAALAAALQNIVVEDDEVAAAAIEYLK 567
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 969 SEKLS-------NAESKINSLQIQLHNTRDALGRESLILERVQRDLSQTQCQKKETEQMYQIEQSKLKKYIAKQESVEER 1041
Cdd:COG1196 568 AAKAGratflplDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLR 647
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1042 LSQLQSENMLLRQQLDDAHKKANSQEKTSSTIQDQfhsaakNLQAESEKQILSLQEKNKELMDEYNHLKERMDQCEKEKA 1121
Cdd:COG1196 648 EVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELE------ELAERLAEEELELEEALLAEEEEERELAEAEEERLEEEL 721
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 149363642 1122 gRKIDLTEAQETVPSRCLHLDAENEVLQLQQTLFSMKAIQKQcETLQKNKKQLKQEV-----VNL 1181
Cdd:COG1196 722 -EEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDL-EELERELERLEREIealgpVNL 784
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
662-1314 |
8.48e-06 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 50.40 E-value: 8.48e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 662 KLKQMENMVSVLQNELsetkKTKlqlelqkiewEKELYDLRLALKQENEEKRNAdmlyNKDSEQLRIKEEEC-GKVVETK 740
Cdd:TIGR04523 34 EEKQLEKKLKTIKNEL----KNK----------EKELKNLDKNLNKDEEKINNS----NNKIKILEQQIKDLnDKLKKNK 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 741 QQLK---WNLRRLVKELRTVRNNLDLVVQERNDAQKQLSEEQDARILQDQILTSKQKELEMARKKMNSEISHRHQKEKDL 817
Cdd:TIGR04523 96 DKINklnSDLSKINSEIKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENEL 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 818 FhedcMLQEEIALLRLEIDTIKNQNKQKEKKYFeDIEAVKEKNDNLQ-KIIKLNEE--TLTETILQYSGQLNNLTAENKI 894
Cdd:TIGR04523 176 N----LLEKEKLNIQKNIDKIKNKLLKLELLLS-NLKKKIQKNKSLEsQISELKKQnnQLKDNIEKKQQEINEKTTEISN 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 895 LNSELENGKQNQERLEIEMESYRCRLAAAvrdcdqSQTARDLKLDFQRTRQEWVRLHDKMKVDMsglqakNEILSEKLSN 974
Cdd:TIGR04523 251 TQTQLNQLKDEQNKIKKQLSEKQKELEQN------NKKIKELEKQLNQLKSEISDLNNQKEQDW------NKELKSELKN 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 975 AESKINSLQIQLHNTRDALGRESLILERVQRDLSQTQCQKKETEQMYQIEQSKLKKYIAKQESVEERLSQLQSENMLLRQ 1054
Cdd:TIGR04523 319 QEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLES 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1055 QLDDahkkansQEKTSSTIQDQFHSAAKNLQaESEKQILSLQEKNKELMDEYNHLKErmDQCEKEKAGRKIDLTEAQETV 1134
Cdd:TIGR04523 399 KIQN-------QEKLNQQKDEQIKKLQQEKE-LLEKEIERLKETIIKNNSEIKDLTN--QDSVKELIIKNLDNTRESLET 468
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1135 PSRCLHLDAENEVLQLQQTLFSMKAIQKQCETLQKNKKQLKQEVVNLKSYMERNMLERGKAEWHKLLIEERArKEIEEKL 1214
Cdd:TIGR04523 469 QLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKI-SDLEDEL 547
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1215 NE-----AILTLQKQAAVSHEQLVQLREDNTTSIKTQMELT--IKDLESEISRIKTSQADFNKTELERYKELYLEEvKVR 1287
Cdd:TIGR04523 548 NKddfelKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQelIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAK-KEN 626
|
650 660
....*....|....*....|....*..
gi 149363642 1288 ESLSNELSRTNEMIAEVSTQLTVEKEQ 1314
Cdd:TIGR04523 627 EKLSSIIKNIKSKKNKLKQEVKQIKET 653
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
658-1297 |
1.65e-05 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 49.79 E-value: 1.65e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 658 QLTVKLKQMENMVSVLQNEL-------SETKKTKLQLELQKIEWEKELYDLRLALkqENEEKRNADMLYNKDSEQLRIKE 730
Cdd:pfam01576 30 ELEKKHQQLCEEKNALQEQLqaetelcAEAEEMRARLAARKQELEEILHELESRL--EEEEERSQQLQNEKKKMQQHIQD 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 731 EECGKVVETKQQLKWNLRRLVKELRTVRNNLDLVVQErnDAQKQLSEEqdARILQDQI--LTS-------KQKELEMARK 801
Cdd:pfam01576 108 LEEQLDEEEAARQKLQLEKVTTEAKIKKLEEDILLLE--DQNSKLSKE--RKLLEERIseFTSnlaeeeeKAKSLSKLKN 183
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 802 K---MNSEISHRHQKE-----------KDLFHEDCMLQEEIALLRLEIDTIKNqnkqkekkyfedieAVKEKNDNLQKII 867
Cdd:pfam01576 184 KheaMISDLEERLKKEekgrqelekakRKLEGESTDLQEQIAELQAQIAELRA--------------QLAKKEEELQAAL 249
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 868 -KLNEETLTETILQYSgqLNNLTAENKILNSELENGKQNQER-------LEIEMESYRCRLAAAVRDCDQSQTARDLK-- 937
Cdd:pfam01576 250 aRLEEETAQKNNALKK--IRELEAQISELQEDLESERAARNKaekqrrdLGEELEALKTELEDTLDTTAAQQELRSKReq 327
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 938 --LDFQRTRQEWVRLHDKMKVDMSGLQAKN-EILSEKLSNAE-SKINslqiqLHNTRDALGRESLILERVQRDLSQ---- 1009
Cdd:pfam01576 328 evTELKKALEEETRSHEAQLQEMRQKHTQAlEELTEQLEQAKrNKAN-----LEKAKQALESENAELQAELRTLQQakqd 402
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1010 TQCQKKETEQMYQIEQSKLKKYIAKQESVEERLSQLQSENMLLRQQLDDAHKKANSQEKTSSTIQDQFHSAAKNLQAESe 1089
Cdd:pfam01576 403 SEHKRKKLEGQLQELQARLSESERQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLESQLQDTQELLQEET- 481
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1090 KQILSLQEKNKELMDEYNHLKERMDQCE--KEKAGRKIDLTEAQETVPSRCLHLDAEN-EVLQ---------LQQTLFSM 1157
Cdd:pfam01576 482 RQKLNLSTRLRQLEDERNSLQEQLEEEEeaKRNVERQLSTLQAQLSDMKKKLEEDAGTlEALEegkkrlqreLEALTQQL 561
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1158 KAIQKQCETLQKNKKQLKQEVVNLKSYMERNM-----LERGKAEWHKLLIEERA----------RKEIEEKLNEAiltlq 1222
Cdd:pfam01576 562 EEKAAAYDKLEKTKNRLQQELDDLLVDLDHQRqlvsnLEKKQKKFDQMLAEEKAisaryaeerdRAEAEAREKET----- 636
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1223 KQAAVSHEQlvqlreDNTTSIKTQMELTIKDLESEISRIKTSQADFNKT--ELERYK---ELYLEEVKVR-ESLSNELSR 1296
Cdd:pfam01576 637 RALSLARAL------EEALEAKEELERTNKQLRAEMEDLVSSKDDVGKNvhELERSKralEQQVEEMKTQlEELEDELQA 710
|
.
gi 149363642 1297 T 1297
Cdd:pfam01576 711 T 711
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
746-1319 |
1.91e-05 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 49.29 E-value: 1.91e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 746 NLRRLVKELRTVRNNLDLVVQERNDAQKQLSEEQDARILQDQILTSKQKELEMARKKMnSEISHRHQKEKDLFHEDCMLQ 825
Cdd:PRK03918 166 NLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREEL-EKLEKEVKELEELKEEIEELE 244
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 826 EEIALLRLEIDTIKNQNKQKEkkyfEDIEAVKEKNDNLQKIIKLNEEtltetilqysgqLNNLTAENKILNSELENGKQN 905
Cdd:PRK03918 245 KELESLEGSKRKLEEKIRELE----ERIEELKKEIEELEEKVKELKE------------LKEKAEEYIKLSEFYEEYLDE 308
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 906 QERLEIEMESYRCRLAAAVRDCDqsqtardlKLDFQRTRQEWvrlhdkMKVDMSGLQAKNEILSEKLSNAEsKINSLQIQ 985
Cdd:PRK03918 309 LREIEKRLSRLEEEINGIEERIK--------ELEEKEERLEE------LKKKLKELEKRLEELEERHELYE-EAKAKKEE 373
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 986 LHNTRDALGRESLilERVQRDLSQTQCQKKE-TEQMYQIEQSK--LKKYIAKQESVEERLSQLQSENMLLRQQLDDAHKK 1062
Cdd:PRK03918 374 LERLKKRLTGLTP--EKLEKELEELEKAKEEiEEEISKITARIgeLKKEIKELKKAIEELKKAKGKCPVCGRELTEEHRK 451
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1063 A---------NSQEKTSSTIQDQFHSAAKNLQaESEKQILSLQE--KNKELMDEYNHLKERMDQCEKEKAGRKidlTEAQ 1131
Cdd:PRK03918 452 ElleeytaelKRIEKELKEIEEKERKLRKELR-ELEKVLKKESEliKLKELAEQLKELEEKLKKYNLEELEKK---AEEY 527
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1132 ETVPSRCLHLdaENEVLQLQQTLFSMKAIQKQCETLQKNKKQLKQEVVNLksymERNMLERGKAEWHKLlieERARKEIE 1211
Cdd:PRK03918 528 EKLKEKLIKL--KGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAEL----LKELEELGFESVEEL---EERLKELE 598
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1212 EKLNEAI-LTLQKQAAVSHEQLVQLREDNTTSIKTQMELTIKDLESEISRIKTSQADFNKTELERYKELYLEEVKVRESL 1290
Cdd:PRK03918 599 PFYNEYLeLKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEELREEYLELSRELAGL 678
|
570 580
....*....|....*....|....*....
gi 149363642 1291 SNELSRTNEMIAEVSTQLTVEKEQTRSRS 1319
Cdd:PRK03918 679 RAELEELEKRREEIKKTLEKLKEELEERE 707
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
1026-1328 |
4.47e-05 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 48.14 E-value: 4.47e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1026 SKLKKYIAKQESVEERLSQLQSENMLLRQQLDDAHKKANSQEK----TSSTIQDQFHSAAKNLQAeSEKQILSLQEKNKE 1101
Cdd:TIGR02169 170 RKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAERyqalLKEKREYEGYELLKEKEA-LERQKEAIERQLAS 248
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1102 LMDEYNHLKERMDQCEKEKAGRKIDLTEAQETVPSRclhldAENEVLQLQQTLFSMKAIQKQC-----------ETLQKN 1170
Cdd:TIGR02169 249 LEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDL-----GEEEQLRVKEKIGELEAEIASLersiaekerelEDAEER 323
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1171 KKQLKQEVVNLKSYME--RNMLERGKAEWHKLLIEERARKEIEEKLNEAILTLQKQAAVSHEQLVQLRE----------- 1237
Cdd:TIGR02169 324 LAKLEAEIDKLLAEIEelEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREkleklkreine 403
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1238 -----DNTTSIKTQMELTIKDLESEISRIKTSQADFNKTELERYKELYLEE------VKVRESLSNELSRTNEMIAEVST 1306
Cdd:TIGR02169 404 lkrelDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEwkleqlAADLSKYEQELYDLKEEYDRVEK 483
|
330 340
....*....|....*....|..
gi 149363642 1307 QLTvEKEQTRSRSLFTAYATRP 1328
Cdd:TIGR02169 484 ELS-KLQRELAEAEAQARASEE 504
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
658-1261 |
7.91e-05 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 47.24 E-value: 7.91e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 658 QLTVKLKQMENMVSVLQNELSETKKTKLQLELQKIEWEKELYDLRLALKQ-ENEEKRNADMLYNKDSEQLRIKEEECGKV 736
Cdd:COG1196 217 ELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEaELEELRLELEELELELEEAQAEEYELLAE 296
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 737 VETKQQlkwNLRRLVKELRTVRNNLDLVVQERNDAQKQLSEEQDARILQDQILTSKQKELEMARKKMNSEISHRHQKEKD 816
Cdd:COG1196 297 LARLEQ---DIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAE 373
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 817 LfhedcmLQEEIALLRLEIdtiknqnkqkekkyfEDIEAVKEKNDNLQKIiklneETLTETILQYSGQLNNLTAENKILN 896
Cdd:COG1196 374 L------AEAEEELEELAE---------------ELLEALRAAAELAAQL-----EELEEAEEALLERLERLEEELEELE 427
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 897 SELENGKQNQERLEIEMESyrcRLAAAVRDCDQSQTARDLKLDFQRTRQEWVRLHDKMKVDMSGLQAKNEILSEKLSNAE 976
Cdd:COG1196 428 EALAELEEEEEEEEEALEE---AAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYE 504
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 977 SKINSLQIQLHNTRDALGRESLILERVQRDLSQTQCQKKETEQMYQI---EQSKLKKYIAK-QESVEERLSQLQSENMLL 1052
Cdd:COG1196 505 GFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIvveDDEVAAAAIEYlKAAKAGRATFLPLDKIRA 584
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1053 RQQLDDAHKKANSQEKTSSTIQDQFHSAAKNLQAESekqILSLQEKNKELMDEYNHLKERMDQCEKEKAGRKIDLTEAQE 1132
Cdd:COG1196 585 RAALAAALARGAIGAAVDLVASDLREADARYYVLGD---TLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGS 661
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1133 TVPSRCLHLDAENEVLQLQQTLfsmkaiqkqcETLQKNKKQLKQEVVNLKSYMERNMLERGKAEWHKLLIEERARKEIEE 1212
Cdd:COG1196 662 LTGGSRRELLAALLEAEAELEE----------LAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLE 731
|
570 580 590 600
....*....|....*....|....*....|....*....|....*....
gi 149363642 1213 KLNEAILTLQKQAAVSHEQLVQLREDNTTSIKTQmELTIKDLESEISRI 1261
Cdd:COG1196 732 AEREELLEELLEEEELLEEEALEELPEPPDLEEL-ERELERLEREIEAL 779
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
646-963 |
9.67e-05 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 47.04 E-value: 9.67e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 646 EHLLKLKNnHCDQLTVKLKQMENMVSVLQNELS-------ETKKTKLQLELQKIEWEKELYDLRLALKQ----------- 707
Cdd:pfam15921 541 DHLRNVQT-ECEALKLQMAEKDKVIEILRQQIEnmtqlvgQHGRTAGAMQVEKAQLEKEINDRRLELQEfkilkdkkdak 619
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 708 -ENEEKRNADM------LYNKDSEQLRikeeecgKVVETKQQLKwnlrRLVKELRTVRNNL-----DLVVQERNDAQKQL 775
Cdd:pfam15921 620 iRELEARVSDLelekvkLVNAGSERLR-------AVKDIKQERD----QLLNEVKTSRNELnslseDYEVLKRNFRNKSE 688
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 776 SEEQDARILQDQiLTSKQKELEMARKKMNS-EISHRHQKEKDLfhedcMLQEEIALLRLEIDTIKNQnkqkekkyfedIE 854
Cdd:pfam15921 689 EMETTTNKLKMQ-LKSAQSELEQTRNTLKSmEGSDGHAMKVAM-----GMQKQITAKRGQIDALQSK-----------IQ 751
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 855 AVKEKNDNLQKiiklNEETLTETILQYSGQLNNLTAENKILNSELENGKQNQERLEIEMESYRCRLAAAVRDCDQSQTAr 934
Cdd:pfam15921 752 FLEEAMTNANK----EKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMEVALDKASLQFAECQDI- 826
|
330 340
....*....|....*....|....*....
gi 149363642 935 dlkldFQRTRQEWVRLHDKMKVDMSGLQA 963
Cdd:pfam15921 827 -----IQRQEQESVRLKLQHTLDVKELQG 850
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
962-1181 |
1.00e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 46.30 E-value: 1.00e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 962 QAKNEILSEKLSNAESKINSLQIQLHNTRDALGRESLILERVQRDLSQTQCQKKETEQMYQIEQSKLKKYIAKQESVEER 1041
Cdd:COG4942 19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1042 LSQLQSEnmlLRQQLDDAHKKANSQEKTSSTIQDQFHSAAKNLQ------AESEKQILSLQEKNKELMDEYNHLKERMDQ 1115
Cdd:COG4942 99 LEAQKEE---LAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQylkylaPARREQAEELRADLAELAALRAELEAERAE 175
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 149363642 1116 CEKEKAGRKIDLTEAQETVPSRclhldaENEVLQLQQTLfsmKAIQKQCETLQKNKKQLKQEVVNL 1181
Cdd:COG4942 176 LEALLAELEEERAALEALKAER------QKLLARLEKEL---AELAAELAELQQEAEELEALIARL 232
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
664-1303 |
1.01e-04 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 46.89 E-value: 1.01e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 664 KQMENMVSVLQNELSETKKTKLQLELQKIEWEKELYDLRLALKQENEEKRNADMLYNKDSEQLRIKEEECGKVVETKQQL 743
Cdd:TIGR00618 141 KTFTRVVLLPQGEFAQFLKAKSKEKKELLMNLFPLDQYTQLALMEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHER 220
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 744 KWNLRRLVKELRTV----RNNLDLVVQERNDAQKQLSEEQDARILQDQI--LTSKQKELEMARKKMN---------SEIS 808
Cdd:TIGR00618 221 KQVLEKELKHLREAlqqtQQSHAYLTQKREAQEEQLKKQQLLKQLRARIeeLRAQEAVLEETQERINrarkaaplaAHIK 300
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 809 HRHQKEKDLFHEDCMLQEEIALL-----------RLEIDTIKNQNKQKEKKYFEDIEAVKEKNDNLQKIIKLNEETLTET 877
Cdd:TIGR00618 301 AVTQIEQQAQRIHTELQSKMRSRakllmkraahvKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQH 380
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 878 ILQYSGQLNNLTAENKILNSELENGKQNQERLEIEMESYRC---RLAAAVRDCDQSQTARDLKLDF-QRTRQ-------E 946
Cdd:TIGR00618 381 IHTLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDlqgQLAHAKKQQELQQRYAELCAAAiTCTAQceklekiH 460
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 947 WVRLHDKMKVDMSGLQAKNEILSEKLSNAESKINSLQIQLHNTRDALGRES-LILERVQRDLSQ-TQCQKKETEQMYQIE 1024
Cdd:TIGR00618 461 LQESAQSLKEREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPLCGSCIhPNPARQDIDNPGpLTRRMQRGEQTYAQL 540
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1025 QSKLKKYIAKQESVEERLSQLQSENMLLRQQLDDAHKKANSQEKTSSTIQDQFHSAAKNLQAESEKQIlSLQEKNKELMD 1104
Cdd:TIGR00618 541 ETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAED-MLACEQHALLR 619
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1105 EYNHLKERMD------QCEKEKAGRKIDLTEAQETVPSR----CLHLDAENEVLQLQQTLFSMKAIQKQCETLQKNKKQL 1174
Cdd:TIGR00618 620 KLQPEQDLQDvrlhlqQCSQELALKLTALHALQLTLTQErvreHALSIRVLPKELLASRQLALQKMQSEKEQLTYWKEML 699
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1175 KQEVVNLKSYMErnmlergkaewhKLLIEERARKEIEEKLNEAILTLQKQAAVSHEQLVQLREDNTTSIKTQMELTIKDL 1254
Cdd:TIGR00618 700 AQCQTLLRELET------------HIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQARTVLKARTEAHFNNN 767
|
650 660 670 680
....*....|....*....|....*....|....*....|....*....
gi 149363642 1255 ESEISRIKTSQadfnktELERYKELYLEEVKVRESLSNELSRTNEMIAE 1303
Cdd:TIGR00618 768 EEVTAALQTGA------ELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQ 810
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
730-1094 |
1.02e-04 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 46.98 E-value: 1.02e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 730 EEECGKVVETKQQLKWNLRRLVKELRTVRNNLDLVVQERNDAQKQLSEEQDARILQDQILTSKQKELEMARKKMNSEISH 809
Cdd:TIGR02169 169 DRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAIERQLAS 248
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 810 RHQKEKDLFHEDCMLQEEIALLRLEIDT----IKNQNKQKEKKYFEDIEAVKEKNDNLQKIIKLNE---ETLTETILQYS 882
Cdd:TIGR02169 249 LEEELEKLTEEISELEKRLEEIEQLLEElnkkIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKErelEDAEERLAKLE 328
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 883 GQLNNLTAENKILNSELENGKQNQERLEIEMESYRCRLAAAVRDcdqsqtARDLKLDFQRTRQEWVRLHdkmkvdmsglq 962
Cdd:TIGR02169 329 AEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAE------LEEVDKEFAETRDELKDYR----------- 391
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 963 akneilsEKLSNAESKINSLQiqlhNTRDALGRESLILERVQRDLSQTQCQKKEteqmyqieqsKLKKYIAKQESVEERL 1042
Cdd:TIGR02169 392 -------EKLEKLKREINELK----RELDRLQEELQRLSEELADLNAAIAGIEA----------KINELEEEKEDKALEI 450
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|...
gi 149363642 1043 SQLQSENMLLRQQLDDAHKKANSQEKTSSTIQDQFHSAAKNL-QAESEKQILS 1094
Cdd:TIGR02169 451 KKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELaEAEAQARASE 503
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
662-1212 |
1.05e-04 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 46.98 E-value: 1.05e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 662 KLKQMENMVSVLQNELSETKKTKLQLELQKIEWEKELYDLRLALKqENEEKRnadmlynKDSEQLRIKEEECGKVVETKQ 741
Cdd:PRK03918 232 ELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIE-ELEEKV-------KELKELKEKAEEYIKLSEFYE 303
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 742 QLKWNLRRLVKELRTVR---NNLDLVVQERNDAQKQLSE--EQDARILQD-QILTSKQKELEMARKKMNSEISHRhQKEK 815
Cdd:PRK03918 304 EYLDELREIEKRLSRLEeeiNGIEERIKELEEKEERLEElkKKLKELEKRlEELEERHELYEEAKAKKEELERLK-KRLT 382
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 816 DLFHEDcmLQEEIALLRLEIDTIKNQNKQKEKKYFEDIEAVKEKNDNLQKIIK-----------LNEETLTETILQYSGQ 884
Cdd:PRK03918 383 GLTPEK--LEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKakgkcpvcgreLTEEHRKELLEEYTAE 460
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 885 LNNLTAENKILNSELENGKQNQERLEIEMESYRcRLAAAVRDCDQSQTARDL--KLDFQRTRQEWvRLHDKMKVDMSGLQ 962
Cdd:PRK03918 461 LKRIEKELKEIEEKERKLRKELRELEKVLKKES-ELIKLKELAEQLKELEEKlkKYNLEELEKKA-EEYEKLKEKLIKLK 538
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 963 AKNEILSEKLSNAESKINSLQIQLHNTRDALGRESLILERVQR----DLSQTQCQKKETEQMYQiEQSKLKKYIAKQESV 1038
Cdd:PRK03918 539 GEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEElgfeSVEELEERLKELEPFYN-EYLELKDAEKELERE 617
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1039 EERLSQLQSENMLLRQQLDDAHKKANsqektsstiqdqfhsaaknlqaESEKQILSLQEKNKElmDEYNHLKERMDQCEK 1118
Cdd:PRK03918 618 EKELKKLEEELDKAFEELAETEKRLE----------------------ELRKELEELEKKYSE--EEYEELREEYLELSR 673
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1119 EKAGRKIDLTEAQEtvpsrclhldaenevlQLQQTLFSMKAIQKQCETLQKNKKQLKqevvNLKSYMERNMLERGKAEWH 1198
Cdd:PRK03918 674 ELAGLRAELEELEK----------------RREEIKKTLEKLKEELEEREKAKKELE----KLEKALERVEELREKVKKY 733
|
570
....*....|....
gi 149363642 1199 KLLIEERARKEIEE 1212
Cdd:PRK03918 734 KALLKERALSKVGE 747
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
850-1320 |
1.76e-04 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 46.12 E-value: 1.76e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 850 FEDIEAVKEKNDNLQKIIKLNEETLTETILQYSGQLNNLTAENKILNSELENGKQNQERLEIEMESYRCR------LAAA 923
Cdd:TIGR00618 186 FAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQKREAQEEQlkkqqlLKQL 265
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 924 VRDCDQSQTA------RDLKLDFQR--------------TRQEWVRLHDKMKVDM----SGLQAKNEILSEKLSNAESK- 978
Cdd:TIGR00618 266 RARIEELRAQeavleeTQERINRARkaaplaahikavtqIEQQAQRIHTELQSKMrsraKLLMKRAAHVKQQSSIEEQRr 345
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 979 -INSLQIQLHNTRDALGRESLILERVQRDLSQTQCQKKETEQ---MYQIEQSKLKKYIAKQESVEERLSQLQSENMLlRQ 1054
Cdd:TIGR00618 346 lLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQHIHTLQQQkttLTQKLQSLCKELDILQREQATIDTRTSAFRDL-QG 424
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1055 QLDDAHKKANSQEKTSStIQDQFhsAAKNLQAESEKQILsLQEKNKELMDEYNHLKERMDQCEKEKAGRKIDLTEAQETV 1134
Cdd:TIGR00618 425 QLAHAKKQQELQQRYAE-LCAAA--ITCTAQCEKLEKIH-LQESAQSLKEREQQLQTKEQIHLQETRKKAVVLARLLELQ 500
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1135 PSRCLHLDAENEVLQLQQTLFSMKAIQKQCETLQKNKKQLKQEVVNLKSYM--ERNMLERGKAE-------WHKLLIEER 1205
Cdd:TIGR00618 501 EEPCPLCGSCIHPNPARQDIDNPGPLTRRMQRGEQTYAQLETSEEDVYHQLtsERKQRASLKEQmqeiqqsFSILTQCDN 580
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1206 ARKEIEEKLNEAILTLQKQAAVSHEQLVQLREDNTTS-IKTQMELTIKDLESEISRIKTSQAdFNKTELERYKELYLEEv 1284
Cdd:TIGR00618 581 RSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALlRKLQPEQDLQDVRLHLQQCSQELA-LKLTALHALQLTLTQE- 658
|
490 500 510
....*....|....*....|....*....|....*.
gi 149363642 1285 KVRESLSneLSRTNEMIAEVSTQLTVEKEQTRSRSL 1320
Cdd:TIGR00618 659 RVREHAL--SIRVLPKELLASRQLALQKMQSEKEQL 692
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
850-1131 |
1.85e-04 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 46.21 E-value: 1.85e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 850 FEDIEAVK-----------EKNDNLQKIIKLNEETLTETILQ----------YSGQLNNLTAENKILNSELENGKQNQER 908
Cdd:TIGR02169 176 LEELEEVEenierldliidEKRQQLERLRREREKAERYQALLkekreyegyeLLKEKEALERQKEAIERQLASLEEELEK 255
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 909 LEIEMESYRCRLAAAVRDCDQ-SQTARDLKLDFQRTRQEWVRlhdKMKVDMSGLQAKNEI-------LSEKLSNAESKIN 980
Cdd:TIGR02169 256 LTEEISELEKRLEEIEQLLEElNKKIKDLGEEEQLRVKEKIG---ELEAEIASLERSIAEkereledAEERLAKLEAEID 332
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 981 SLQIQLHNTRDALGRESLILERVQ---------RDLSQTQCQKKETE-----QMYQIEQSKLKKYIAKQESVEERLSQLQ 1046
Cdd:TIGR02169 333 KLLAEIEELEREIEEERKRRDKLTeeyaelkeeLEDLRAELEEVDKEfaetrDELKDYREKLEKLKREINELKRELDRLQ 412
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1047 SENMLLRQQLDDAHKKANSQEKTSSTIQDQFHSAAKNLqAESEKQILSLQEKNKELMDEYNHLKERMDQCEKE--KAGRK 1124
Cdd:TIGR02169 413 EELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEI-KKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKElsKLQRE 491
|
....*..
gi 149363642 1125 IDLTEAQ 1131
Cdd:TIGR02169 492 LAEAEAQ 498
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
1026-1320 |
2.62e-04 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 45.50 E-value: 2.62e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1026 SKLKKYIAKQESVEERLSQLQSENMLLRQQLDDAHKKANSQEKtsstiQDQFHSAAKNLQAESEKQILSLQEKNKELMDE 1105
Cdd:pfam17380 272 NQLLHIVQHQKAVSERQQQEKFEKMEQERLRQEKEEKAREVER-----RRKLEEAEKARQAEMDRQAAIYAEQERMAMER 346
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1106 YNHLkERMDQCEKEKAGRKIDLTE-AQETVPSR---CLHLDAENEVLQLQQTLFSMKAIQKQCETLQKNKKQLKQEVVNL 1181
Cdd:pfam17380 347 EREL-ERIRQEERKRELERIRQEEiAMEISRMReleRLQMERQQKNERVRQELEAARKVKILEEERQRKIQQQKVEMEQI 425
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1182 ksymeRNMLERGKAEWHKLLIEERARKEIEEKLNEailtLQKQaavshEQLVQLREDNTTSIKTQMELTIKdlESEISRI 1261
Cdd:pfam17380 426 -----RAEQEEARQREVRRLEEERAREMERVRLEE----QERQ-----QQVERLRQQEEERKRKKLELEKE--KRDRKRA 489
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*....
gi 149363642 1262 KTSQADFNKTELERYKELYLEEVKVRESLSNELSRTNEMIAEVSTQLTVEKEQTRSRSL 1320
Cdd:pfam17380 490 EEQRRKILEKELEERKQAMIEEERKRKLLEKEMEERQKAIYEEERRREAEEERRKQQEM 548
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
662-1255 |
3.21e-04 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 45.49 E-value: 3.21e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 662 KLKQMENMVSVLQNELSETKKT---KL-QLELQKIEWEKELYDLRLALKQENEEKRNADMLYNKDSEQLRIKEEECGKVV 737
Cdd:pfam15921 318 QLSDLESTVSQLRSELREAKRMyedKIeELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELSLEK 397
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 738 ETKQQLkWNlrrlvkelRTVRNNLDLvvqerndaqKQLSEEQDARILQDQiltskqkELEMARKKMNSEishrhqkekdl 817
Cdd:pfam15921 398 EQNKRL-WD--------RDTGNSITI---------DHLRRELDDRNMEVQ-------RLEALLKAMKSE----------- 441
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 818 fhedCMLQEEiallrleidtiknqnkqkekkyfEDIEAVKEKNDNLQKIiklneETLTETILQYSGQLNNLTAENKILNS 897
Cdd:pfam15921 442 ----CQGQME-----------------------RQMAAIQGKNESLEKV-----SSLTAQLESTKEMLRKVVEELTAKKM 489
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 898 ELENGKQNQERLEIEMESYRCRLAAAVRDCDQSQTARDLKL-DFQRTRQEWVRLHDkmkvdmsgLQAKNEILSEKLSNAE 976
Cdd:pfam15921 490 TLESSERTVSDLTASLQEKERAIEATNAEITKLRSRVDLKLqELQHLKNEGDHLRN--------VQTECEALKLQMAEKD 561
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 977 SKINSLQIQLHNTRDALGRESLILERVQrdLSQTQCQKKETEQMYQIEQSKL--KKYIAKQESVEERLSQLQSENMLL-- 1052
Cdd:pfam15921 562 KVIEILRQQIENMTQLVGQHGRTAGAMQ--VEKAQLEKEINDRRLELQEFKIlkDKKDAKIRELEARVSDLELEKVKLvn 639
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1053 ---------------RQQLDDAHKKA----NSQEKTSSTIQDQFHSAAKNLQAESEKQILSLQEKNKELMDEYNHLKErM 1113
Cdd:pfam15921 640 agserlravkdikqeRDQLLNEVKTSrnelNSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKS-M 718
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1114 DQCEKEKAGRKIDLteaQETVPSRCLHLDAENEVLQLQQTlfSMKAIQKQCETLQKNKKQLKQEVVNLKSymERNMLerg 1193
Cdd:pfam15921 719 EGSDGHAMKVAMGM---QKQITAKRGQIDALQSKIQFLEE--AMTNANKEKHFLKEEKNKLSQELSTVAT--EKNKM--- 788
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 149363642 1194 KAEWHKLLIEERARKEIEEKLNEAILTLQKQAAVSHEqLVQLREDNTTSIKTQMELTIKDLE 1255
Cdd:pfam15921 789 AGELEVLRSQERRLKEKVANMEVALDKASLQFAECQD-IIQRQEQESVRLKLQHTLDVKELQ 849
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
968-1313 |
3.60e-04 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 44.51 E-value: 3.60e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 968 LSEKLSNAESKINSLQIQLHNTRDALGRESLILERVQRDLSQTQCQKKETEQMYQIEQSKLKKYIAKQESVEERLSQLQS 1047
Cdd:COG4372 29 LSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQE 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1048 ENMLLRQQLDDAHKKANSQEKTSSTIQDQfhsaaknlQAESEKQILSLQEKNKELMDEYNHLKERMDQCEKEKAGRKIDL 1127
Cdd:COG4372 109 EAEELQEELEELQKERQDLEQQRKQLEAQ--------IAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAE 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1128 TEAQ--ETVPSRCLHLDAENEVLQLQQTLFSMKAIQKQCETLQKNKKQLKQEVVNLKSYMERNMLERG-KAEWHKLLIEE 1204
Cdd:COG4372 181 AEQAldELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKeELLEEVILKEI 260
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1205 RARKEIEEKLNEAILTLQKQAAVSHEQLVQLREDNTTSIKTQMELTIKDLESEISRIKTSQADFNKTELERYKELYLEEV 1284
Cdd:COG4372 261 EELELAILVEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLELALAILLAELA 340
|
330 340
....*....|....*....|....*....
gi 149363642 1285 KVRESLSNELSRTNEMIAEVSTQLTVEKE 1313
Cdd:COG4372 341 DLLQLLLVGLLDNDVLELLSKGAEAGVAD 369
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
819-1312 |
3.91e-04 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 45.01 E-value: 3.91e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 819 HEDCMLQEEIALLRLEIDTIKNQNKQKEKKYFEDIEAVKEKNDNLqKIIKLNEETLTETILQYSGQLNNLTAENKILNSE 898
Cdd:TIGR04523 33 TEEKQLEKKLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKI-KILEQQIKDLNDKLKKNKDKINKLNSDLSKINSE 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 899 LENGKQNQERLEIEMESyrcrlaaavrdcdqsqtardlkldFQRTRQEWVRLHDKMKVDMSGLQAKNEILSEKLSNAESK 978
Cdd:TIGR04523 112 IKNDKEQKNKLEVELNK------------------------LEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQ 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 979 INSLQIQLHNTRDAlgresliLERVQRDLSQTQCQKKETEQMYqieqSKLKKYIAKQESVEERLSQLQSENMLLRQQLDD 1058
Cdd:TIGR04523 168 KEELENELNLLEKE-------KLNIQKNIDKIKNKLLKLELLL----SNLKKKIQKNKSLESQISELKKQNNQLKDNIEK 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1059 AHKKANSQEKTSSTIQDQFhsaaKNLQAESEKQILSLQEKNKELMDEYNHLKERMDQCEKEKAGRKiDLTEAQETVPSRC 1138
Cdd:TIGR04523 237 KQQEINEKTTEISNTQTQL----NQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEIS-DLNNQKEQDWNKE 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1139 LHLDAENEVLQLQQtlfsmkaIQKQCETLQKNKKQLKQEVVNLKSymERNMLERGKAEwhkllieerARKEIEEKLNEaI 1218
Cdd:TIGR04523 312 LKSELKNQEKKLEE-------IQNQISQNNKIISQLNEQISQLKK--ELTNSESENSE---------KQRELEEKQNE-I 372
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1219 LTLQKQAAVSHEQLVQLrednttsiktqmELTIKDLESEISRIK--TSQADFNKTELERYKELYLEEVkvrESLSNELSR 1296
Cdd:TIGR04523 373 EKLKKENQSYKQEIKNL------------ESQINDLESKIQNQEklNQQKDEQIKKLQQEKELLEKEI---ERLKETIIK 437
|
490
....*....|....*.
gi 149363642 1297 TNEMIAEVSTQLTVEK 1312
Cdd:TIGR04523 438 NNSEIKDLTNQDSVKE 453
|
|
| MAD |
pfam05557 |
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ... |
890-1279 |
5.17e-04 |
|
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.
Pssm-ID: 461677 [Multi-domain] Cd Length: 660 Bit Score: 44.35 E-value: 5.17e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 890 AENKILNSELENGKQNQERLEIEMESYRCRLAAAvrdcdqsqtARDLKLDFQRTRQEWVRLHDKMKVDMSGLQAKNEILS 969
Cdd:pfam05557 2 AELIESKARLSQLQNEKKQMELEHKRARIELEKK---------ASALKRQLDRESDRNQELQKRIRLLEKREAEAEEALR 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 970 EKLSNAESKINSLQIqlhntrdalgresliLERVQRDLSQTQCQKKETEQMYQIEQSKLKKYIAKQESveeRLSQLQSEN 1049
Cdd:pfam05557 73 EQAELNRLKKKYLEA---------------LNKKLNEKESQLADAREVISCLKNELSELRRQIQRAEL---ELQSTNSEL 134
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1050 MLLRQQLDDAHKKANSQEKTSSTIQDQFHS-AAKNLQAESEKQILSLQEKNKELMDEYNHLKERMDQCEKEKAgrkidlt 1128
Cdd:pfam05557 135 EELQERLDLLKAKASEAEQLRQNLEKQQSSlAEAEQRIKELEFEIQSQEQDSEIVKNSKSELARIPELEKELE------- 207
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1129 eaqetvpsrclHLDAENEVLQlqqtlfsmkaiqkqceTLQKNKKQLKQEVVNLKSYMERnmLERGKAEWHKLLIEeraRK 1208
Cdd:pfam05557 208 -----------RLREHNKHLN----------------ENIENKLLLKEEVEDLKRKLER--EEKYREEAATLELE---KE 255
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1209 EIEEKLNE-------AILTLQKQAAVShEQLVQLREDN---------TTSIKTQMELTIKDLESEISRIKTSQADFNKtE 1272
Cdd:pfam05557 256 KLEQELQSwvklaqdTGLNLRSPEDLS-RRIEQLQQREivlkeenssLTSSARQLEKARRELEQELAQYLKKIEDLNK-K 333
|
....*..
gi 149363642 1273 LERYKEL 1279
Cdd:pfam05557 334 LKRHKAL 340
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
646-1321 |
9.50e-04 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 43.89 E-value: 9.50e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 646 EHLLKLKNNHCDQLTVKLKQMENMV-SVLQNELSETKKTKLQLELQKIEWEKELYDLRLALKQEN----------EEKRN 714
Cdd:TIGR01612 1135 EEIKKKSENYIDEIKAQINDLEDVAdKAISNDDPEEIEKKIENIVTKIDKKKNIYDEIKKLLNEIaeiekdktslEEVKG 1214
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 715 ADMLYNKDSEQLRIKeeecgKVVETKQQLKwnlrRLVKELRTVRNNLDLVVQERNDAQKQLSEEQDARILQD--QILTSK 792
Cdd:TIGR01612 1215 INLSYGKNLGKLFLE-----KIDEEKKKSE----HMIKAMEAYIEDLDEIKEKSPEIENEMGIEMDIKAEMEtfNISHDD 1285
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 793 QKELEMARKKMNSEISHRHQKEKDLFhEDCMLQEEIALLRLEIDTiknqNKQKEKKYFEDIEAVKEKNDNLQKIIKLNE- 871
Cdd:TIGR01612 1286 DKDHHIISKKHDENISDIREKSLKII-EDFSEESDINDIKKELQK----NLLDAQKHNSDINLYLNEIANIYNILKLNKi 1360
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 872 ETLTETILQYSgqlNNLTAENKILNSELENGKQNQERLE--IEMESYRCRLAAAVRDCDQSQTARDLKLDFQRTRQEWVR 949
Cdd:TIGR01612 1361 KKIIDEVKEYT---KEIEENNKNIKDELDKSEKLIKKIKddINLEECKSKIESTLDDKDIDECIKKIKELKNHILSEESN 1437
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 950 LHDKMKvdmsGLQAKNEILSEKLSNAESKINSLQIQLHNTRD-ALGRESLILERVQRDLSQTQCQKKETEQ-MYQIEQSK 1027
Cdd:TIGR01612 1438 IDTYFK----NADENNENVLLLFKNIEMADNKSQHILKIKKDnATNDHDFNINELKEHIDKSKGCKDEADKnAKAIEKNK 1513
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1028 LKKYIAKQE-----------SVEERLSQLQSENMLLRQQLDDAHKK-----ANSQEKTSSTIQDQFH---SAAKNlqAES 1088
Cdd:TIGR01612 1514 ELFEQYKKDvtellnkysalAIKNKFAKTKKDSEIIIKEIKDAHKKfileaEKSEQKIKEIKKEKFRiedDAAKN--DKS 1591
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1089 EKQILSLQEKNKELMDEY---NHLKERMDQCEKEKagrkidlteaqETVPSRCLHLDAENEVLQLQQTLFSMKAIQKQCE 1165
Cdd:TIGR01612 1592 NKAAIDIQLSLENFENKFlkiSDIKKKINDCLKET-----------ESIEKKISSFSIDSQDTELKENGDNLNSLQEFLE 1660
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1166 TLQKNKKQL---KQEVVNLKSYME--RNMLERGKAEWHKLLIEE-----RARKEIEEKLNEAILTLQKQAAVS------- 1228
Cdd:TIGR01612 1661 SLKDQKKNIedkKKELDELDSEIEkiEIDVDQHKKNYEIGIIEKikeiaIANKEEIESIKELIEPTIENLISSfntndle 1740
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1229 ------------------HEQLVQLREDNTTSIKTQMELTIKDLESEISRIkTSQADFNKT-ELERYKELYLEEVKVRE- 1288
Cdd:TIGR01612 1741 gidpnekleeynteigdiYEEFIELYNIIAGCLETVSKEPITYDEIKNTRI-NAQNEFLKIiEIEKKSKSYLDDIEAKEf 1819
|
730 740 750 760
....*....|....*....|....*....|....*....|....*....
gi 149363642 1289 ----------------SLSNELSRTNEMIAEVSTQLTVEKEQTRSRSLF 1321
Cdd:TIGR01612 1820 driinhfkkkldhvndKFTKEYSKINEGFDDISKSIENVKNSTDENLLF 1868
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
851-1072 |
1.58e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 42.44 E-value: 1.58e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 851 EDIEAVKEKNDNLQKIIKLNE----------ETLTETILQYSGQLNNLTAENKILNSELENGKQNQERLEIEMESYRCRL 920
Cdd:COG4942 27 AELEQLQQEIAELEKELAALKkeekallkqlAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEEL 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 921 AAAVRDCDQSQTARDLKLDF-QRTRQEWVRLHDKMKVDMSGLQAKNEILSEKLSNAESKINSLQIQLhntrdalgresli 999
Cdd:COG4942 107 AELLRALYRLGRQPPLALLLsPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAER------------- 173
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 149363642 1000 lERVQRDLSQTQCQKKETEQMYQIEQSKLKKYIAKQESVEERLSQLQSENMLLRQQLDDAHKKANSQEKTSST 1072
Cdd:COG4942 174 -AELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
662-910 |
1.60e-03 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 43.13 E-value: 1.60e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 662 KLKQMENMVSVLQNELSETKKTKLQLELQKIEWEKELYDLRLALKQENEEKRNADmlynkDSEQLRIK------------ 729
Cdd:TIGR02169 231 EKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLG-----EEEQLRVKekigeleaeias 305
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 730 ----------------------EEECGKVVETKQQLKWNLRRLVKELRTVRNNLDLVVQERNDAQKQLSE-EQDARILQD 786
Cdd:TIGR02169 306 lersiaekereledaeerlaklEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEvDKEFAETRD 385
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 787 QiLTSKQKELEMARKKMNSeishrHQKEKD-LFHEDCMLQEEIALLRLEIDTIKNQNKQKEKKYFEDIEAVKEKNDNLQK 865
Cdd:TIGR02169 386 E-LKDYREKLEKLKREINE-----LKRELDrLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQ 459
|
250 260 270 280
....*....|....*....|....*....|....*....|....*
gi 149363642 866 IIKLNEEtltetilqYSGQLNNLTAENKILNSELENGKQNQERLE 910
Cdd:TIGR02169 460 LAADLSK--------YEQELYDLKEEYDRVEKELSKLQRELAEAE 496
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
754-1308 |
1.82e-03 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 42.72 E-value: 1.82e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 754 LRTVRNNLDLVvqernDAQKQLSEEQDarilqdqiLTSKQKELEMARKKMNSEISH----RHQKEKDLFHEDCML----- 824
Cdd:PRK02224 182 LSDQRGSLDQL-----KAQIEEKEEKD--------LHERLNGLESELAELDEEIERyeeqREQARETRDEADEVLeehee 248
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 825 -QEEIALLRLEIDTIKNQNKQKEKKYFEDIEAVKEKNDNLQKIIKLNEETLTETILQ------YSGQLNNLTAENKILNS 897
Cdd:PRK02224 249 rREELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDdadaeaVEARREELEDRDEELRD 328
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 898 ELENGKQNQERLEIEMESYRCRLA-----------AAVRDCDQSQTARDlKLDFQRTRQEWVR--LHDKMK------VDM 958
Cdd:PRK02224 329 RLEECRVAAQAHNEEAESLREDADdleeraeelreEAAELESELEEARE-AVEDRREEIEELEeeIEELRErfgdapVDL 407
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 959 SGLQAKNEILSEKLSNAESKINSLQIQLHNTRDAlgresliLERVQRDLSQTQCqkKETEQmyQIEQS----KLKKYIAK 1034
Cdd:PRK02224 408 GNAEDFLEELREERDELREREAELEATLRTARER-------VEEAEALLEAGKC--PECGQ--PVEGSphveTIEEDRER 476
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1035 QESVEERLSQLQSENMLLRQQLDDAhKKANSQEKTSSTIQDQfHSAAKNLQAESEKQILSLQEKNKELMDEYNHLKERMD 1114
Cdd:PRK02224 477 VEELEAELEDLEEEVEEVEERLERA-EDLVEAEDRIERLEER-REDLEELIAERRETIEEKRERAEELRERAAELEAEAE 554
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1115 QCEKEKAGRKIDLTEAQETVPsrclhlDAENEVLQLQQTLFSMKAIQKQCETLQKNKKQLKQEVVNLKSYMERNMLERGK 1194
Cdd:PRK02224 555 EKREAAAEAEEEAEEAREEVA------ELNSKLAELKERIESLERIRTLLAAIADAEDEIERLREKREALAELNDERRER 628
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1195 aewhklLIEERARK-EIEEKLNEA-ILTLQKQAAVSHEQLVQLRE--DNTTSIKTQMELTIKDLESEISRIKTSQadfnk 1270
Cdd:PRK02224 629 ------LAEKRERKrELEAEFDEArIEEAREDKERAEEYLEQVEEklDELREERDDLQAEIGAVENELEELEELR----- 697
|
570 580 590
....*....|....*....|....*....|....*...
gi 149363642 1271 telERYKELYlEEVKVRESLSNELSRTNEMIAEVSTQL 1308
Cdd:PRK02224 698 ---ERREALE-NRVEALEALYDEAEELESMYGDLRAEL 731
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
649-1068 |
2.08e-03 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 42.45 E-value: 2.08e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 649 LKLKNNHCDQLTVKLKQMENMVSVLQNELSEtkktkLQLELQKIEWEKELYDLRLALKQENEEKRNADMLYnkdsEQLRI 728
Cdd:COG4717 83 AEEKEEEYAELQEELEELEEELEELEAELEE-----LREELEKLEKLLQLLPLYQELEALEAELAELPERL----EELEE 153
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 729 KEEECGKVVETKQQLKWNLRRLVKELRTVRNNLDLVVQER-NDAQKQLSEEQDARILQDQILTSKQKELEMARKKMNS-E 806
Cdd:COG4717 154 RLEELRELEEELEELEAELAELQEELEELLEQLSLATEEElQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQlE 233
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 807 ISHRHQKEKDLFHEDCMLQEEIALLrLEIDTIKNQNKQKEKKYFEDIEAVKEkndnLQKIIKLNEETLTETILQYSGQLN 886
Cdd:COG4717 234 NELEAAALEERLKEARLLLLIAAAL-LALLGLGGSLLSLILTIAGVLFLVLG----LLALLFLLLAREKASLGKEAEELQ 308
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 887 NLTAENKILNSELENGKQNQ---ERLEIEMESYRCRLAAAVRDCDQSQTARDLKLDFQRTRQEWVRLHDKMKVDMSGLQA 963
Cdd:COG4717 309 ALPALEELEEEELEELLAALglpPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIAALLAEAGVEDEEELR 388
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 964 KNEILSEKLSNAESKINSLQIQLHNTRDALGRESLIL--ERVQRDLSQTQCQKKETEQmyqieqsKLKKYIAKQESVEER 1041
Cdd:COG4717 389 AALEQAEEYQELKEELEELEEQLEELLGELEELLEALdeEELEEELEELEEELEELEE-------ELEELREELAELEAE 461
|
410 420
....*....|....*....|....*....
gi 149363642 1042 LSQLQSENML--LRQQLDDAHKKANSQEK 1068
Cdd:COG4717 462 LEQLEEDGELaeLLQELEELKAELRELAE 490
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
867-1211 |
2.74e-03 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 42.03 E-value: 2.74e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 867 IKLNEETLTETilQYSGQLNNLTAENKILNSELENGK---QNQERLEIEMESyRCRLAAAVRDCDQSQTARDLKLDFQRT 943
Cdd:pfam17380 258 VRYNGQTMTEN--EFLNQLLHIVQHQKAVSERQQQEKfekMEQERLRQEKEE-KAREVERRRKLEEAEKARQAEMDRQAA 334
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 944 ---RQEWVRLHDKMKVDMSGLQAKN----EILSEKLSNAESKINSLQ-IQLHNTR-DALGRESLILERVQRDLSQTQcQK 1014
Cdd:pfam17380 335 iyaEQERMAMERERELERIRQEERKreleRIRQEEIAMEISRMRELErLQMERQQkNERVRQELEAARKVKILEEER-QR 413
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1015 KETEQMYQIEQSKLKKYIAKQESVEERLSQLQSENMLLRQQlddahkKANSQEKTSSTIQDQFHSAAKNLQAESEKQILS 1094
Cdd:pfam17380 414 KIQQQKVEMEQIRAEQEEARQREVRRLEEERAREMERVRLE------EQERQQQVERLRQQEEERKRKKLELEKEKRDRK 487
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1095 LQEKNKELMDEyNHLKERMDQCEKEKAGRKI---DLTEAQETVPSRCLHLDAENEvLQLQQTLFSMKAIQKQCETLQKNK 1171
Cdd:pfam17380 488 RAEEQRRKILE-KELEERKQAMIEEERKRKLlekEMEERQKAIYEEERRREAEEE-RRKQQEMEERRRIQEQMRKATEER 565
|
330 340 350 360
....*....|....*....|....*....|....*....|
gi 149363642 1172 KQLKQevvnlksymernmLERGKAEWHKLLIEERARKEIE 1211
Cdd:pfam17380 566 SRLEA-------------MEREREMMRQIVESEKARAEYE 592
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
657-835 |
3.76e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 41.29 E-value: 3.76e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 657 DQLTVKLKQMENMVSVLQNELSETKKTKLQLELQKIEWEKELYDLRLALKQENeekRNADMLYNKDSEQLRIKEEECGKV 736
Cdd:COG4942 58 AALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAELL---RALYRLGRQPPLALLLSPEDFLDA 134
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 737 VETKQQLKW---NLRRLVKELRTVRNNLDLVVQERNDAQKQLSEEQDARILQDQILTSKQKELEMARKKMNSEISHRHQK 813
Cdd:COG4942 135 VRRLQYLKYlapARREQAEELRADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAE 214
|
170 180
....*....|....*....|..
gi 149363642 814 EKDLFHEDCMLQEEIALLRLEI 835
Cdd:COG4942 215 LAELQQEAEELEALIARLEAEA 236
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
659-996 |
3.79e-03 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 42.03 E-value: 3.79e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 659 LTVKLKQMENMVSVLQNELSETKkTKLQLELQKIEwekelydlrlALKQENEEKRNAdmlyNKDSEQLRIKEEECGKVVE 738
Cdd:pfam15921 501 LTASLQEKERAIEATNAEITKLR-SRVDLKLQELQ----------HLKNEGDHLRNV----QTECEALKLQMAEKDKVIE 565
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 739 TKQQLKWNLRRLVKEL-RTVRNNLDLVVQERNDAQKQLSEEQDARILQDQI------LTSKQKELEMARKKMNSEISHRH 811
Cdd:pfam15921 566 ILRQQIENMTQLVGQHgRTAGAMQVEKAQLEKEINDRRLELQEFKILKDKKdakireLEARVSDLELEKVKLVNAGSERL 645
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 812 QKEKDLFHEDCMLQEEIALLRLEIDTIKNQNKQKEKKYFEDIEAVKEKNDNLQKIIKLNEETLTET-------------- 877
Cdd:pfam15921 646 RAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQSELEQTrntlksmegsdgha 725
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 878 ----------ILQYSGQLNNLTAENKILNSELENGKQNQERLEIEMESYRCRLAAAVRDcdqsqtardlkldfqrtrqew 947
Cdd:pfam15921 726 mkvamgmqkqITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATE--------------------- 784
|
330 340 350 360
....*....|....*....|....*....|....*....|....*....
gi 149363642 948 vrlHDKMKVDMSGLQAKNEILSEKLSNAESKINSLQIQLHNTRDALGRE 996
Cdd:pfam15921 785 ---KNKMAGELEVLRSQERRLKEKVANMEVALDKASLQFAECQDIIQRQ 830
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
854-1101 |
3.87e-03 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 41.35 E-value: 3.87e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 854 EAVKEKNDNLQKIIKLNEEtltetILQYSGQLNNLTAENKILNSELENGKQNQERLEIEMESYRCRLAAAVRDcdqsqta 933
Cdd:COG3883 27 ELQAELEAAQAELDALQAE-----LEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARA------- 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 934 rdlkldfqrtrqewvrlhdkMKVDMSGLQAKNEIL-SEKLSNAESKINSLQIQLHNTRDalgreslILERVQRDLSQTQC 1012
Cdd:COG3883 95 --------------------LYRSGGSVSYLDVLLgSESFSDFLDRLSALSKIADADAD-------LLEELKADKAELEA 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1013 QKKETEQMYQIEQSKLKKYIAKQESVEERLSQLQSENMLLRQQLDDAHKKANSQEKTSSTIQDQFHSAAKNLQAESEKQI 1092
Cdd:COG3883 148 KKAELEAKLAELEALKAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAA 227
|
....*....
gi 149363642 1093 LSLQEKNKE 1101
Cdd:COG3883 228 AAAAAAAAA 236
|
|
| CCDC14 |
pfam15254 |
Coiled-coil domain-containing protein 14; This protein family, Coiled-coil domain-containing ... |
1042-1152 |
4.69e-03 |
|
Coiled-coil domain-containing protein 14; This protein family, Coiled-coil domain-containing protein 14 (CCDC14) is a domain of unknown function. This family of proteins is found in eukaryotes. Proteins in this family are typically between 301 and 912 amino acids in length.
Pssm-ID: 464594 Cd Length: 857 Bit Score: 41.32 E-value: 4.69e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1042 LSQLQSENMLLRQQLDDAHKKANSQEKTSSTIQDQ--------FHSAAKNLQA---ESEKQILSLQEKNKELM------- 1103
Cdd:pfam15254 389 LQPLRSENAQLRRQLRILNQQLREQEKTEKTSGSGdcnlelfsLQSLNMSLQNqlqESLKSQELLQSKNEELLkvienqk 468
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 149363642 1104 DEYNH-----------LKERMDQCEKEKAGRKIDLTEAQETVPSRCLHLDA---ENEVL--QLQQ 1152
Cdd:pfam15254 469 EENKKltkifkekeqtLLENKQQFDIETTRVKIELEEALVNMKSFQFKLEAaekENQILgiTLRQ 533
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
961-1095 |
4.80e-03 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 41.30 E-value: 4.80e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 961 LQAKNEILSEK------LSNAESKINSLQIQLHNTRDALGRESLILERVQRDLSQTQCQKKETEQMYQIEQSKLKKYIAK 1034
Cdd:PRK12704 60 LEAKEEIHKLRnefekeLRERRNELQKLEKRLLQKEENLDRKLELLEKREEELEKKEKELEQKQQELEKKEEELEELIEE 139
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 149363642 1035 QESVEERLSQLQSE---NMLLRQQlddahkKANSQEKTSSTIQdQFHSAAKnLQAESE-KQILSL 1095
Cdd:PRK12704 140 QLQELERISGLTAEeakEILLEKV------EEEARHEAAVLIK-EIEEEAK-EEADKKaKEILAQ 196
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
665-1191 |
4.84e-03 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 41.64 E-value: 4.84e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 665 QMENMVSVLQNelsetkKTKLQLELQKIEWEKELYDLRLALKQENEEKRNADMLYNKDSEQLRIKEEEC----GKVVETK 740
Cdd:pfam15921 246 QLEALKSESQN------KIELLLQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQArnqnSMYMRQL 319
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 741 QQLKWNLRRLVKELRTVRNNLDLVVQErndAQKQL----SEEQDARILQDQI------LTSKQKELEMARKKMNSEISHR 810
Cdd:pfam15921 320 SDLESTVSQLRSELREAKRMYEDKIEE---LEKQLvlanSELTEARTERDQFsqesgnLDDQLQKLLADLHKREKELSLE 396
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 811 HQKEKDLFHEDCMLQEEIALLRLEIDtiknqnkqkekkyfedieavkEKNDNLQKIIKLNEETLTETILQYSGQLNNLTA 890
Cdd:pfam15921 397 KEQNKRLWDRDTGNSITIDHLRRELD---------------------DRNMEVQRLEALLKAMKSECQGQMERQMAAIQG 455
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 891 ENKIL------NSELENGKQNQERLEIEMESYRCRLAAAVRD-CDQSQTARDLKLDFQRTRQEWVRLHDKMKVDMSGLQ- 962
Cdd:pfam15921 456 KNESLekvsslTAQLESTKEMLRKVVEELTAKKMTLESSERTvSDLTASLQEKERAIEATNAEITKLRSRVDLKLQELQh 535
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 963 AKNEilSEKLSNAESKINSLQIQLHNTRDALGreslILERVQRDLSQTQCQKKETEQMYQIEQSKLKKYI---------- 1032
Cdd:pfam15921 536 LKNE--GDHLRNVQTECEALKLQMAEKDKVIE----ILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEIndrrlelqef 609
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1033 --------AKQESVEERLSQLQSENMLL-----------------RQQLDDAHKKA----NSQEKTSSTIQDQFHSAAKN 1083
Cdd:pfam15921 610 kilkdkkdAKIRELEARVSDLELEKVKLvnagserlravkdikqeRDQLLNEVKTSrnelNSLSEDYEVLKRNFRNKSEE 689
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1084 LQAESEKQILSLQEKNKELMDEYNHLKER-------------MDQCEKEKAGR------KIDLTEAQETVPSRCLHLDAE 1144
Cdd:pfam15921 690 METTTNKLKMQLKSAQSELEQTRNTLKSMegsdghamkvamgMQKQITAKRGQidalqsKIQFLEEAMTNANKEKHFLKE 769
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|..
gi 149363642 1145 nEVLQLQQTLfSMKAIQK-----QCETLQKNKKQLKQEVVNLKSYMERNMLE 1191
Cdd:pfam15921 770 -EKNKLSQEL-STVATEKnkmagELEVLRSQERRLKEKVANMEVALDKASLQ 819
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
1043-1220 |
6.42e-03 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 40.92 E-value: 6.42e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1043 SQLQSENMLLRQQLDDAHKKANSQEKTS-STIQDQFHSAAKNLQAESEKQILSLQEKNKELMDEYNHLKERMDQCEKEKa 1121
Cdd:PRK12704 31 AKIKEAEEEAKRILEEAKKEAEAIKKEAlLEAKEEIHKLRNEFEKELRERRNELQKLEKRLLQKEENLDRKLELLEKRE- 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1122 gRKIDlteaqetvpsrclhlDAENEVLQLQQTLfsmKAIQKQCETLQKNKKQLKQEVVNLKSYMERNML-----ERGKAE 1196
Cdd:PRK12704 110 -EELE---------------KKEKELEQKQQEL---EKKEEELEELIEEQLQELERISGLTAEEAKEILlekveEEARHE 170
|
170 180
....*....|....*....|....*.
gi 149363642 1197 WHKLL--IEERARKEIEEKLNEAILT 1220
Cdd:PRK12704 171 AAVLIkeIEEEAKEEADKKAKEILAQ 196
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
1088-1257 |
6.76e-03 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 40.92 E-value: 6.76e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1088 SEKQILSLQEKNKELMDEYnhlKERMDQCEKEKagrkidLTEAQETVPSRCLHLDAE-----NEVLQLQQTLfsmkaIQK 1162
Cdd:PRK12704 29 AEAKIKEAEEEAKRILEEA---KKEAEAIKKEA------LLEAKEEIHKLRNEFEKElrerrNELQKLEKRL-----LQK 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1163 QcETLQKNKKQLKQEvvnlksymERNMLERGKAEWHKLLIEERARKEIEEKLNEAILTLQKQAAVSHEQ-----LVQLRE 1237
Cdd:PRK12704 95 E-ENLDRKLELLEKR--------EEELEKKEKELEQKQQELEKKEEELEELIEEQLQELERISGLTAEEakeilLEKVEE 165
|
170 180
....*....|....*....|
gi 149363642 1238 DnttsIKTQMELTIKDLESE 1257
Cdd:PRK12704 166 E----ARHEAAVLIKEIEEE 181
|
|
| PRK11281 |
PRK11281 |
mechanosensitive channel MscK; |
1140-1309 |
8.22e-03 |
|
mechanosensitive channel MscK;
Pssm-ID: 236892 [Multi-domain] Cd Length: 1113 Bit Score: 40.67 E-value: 8.22e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1140 HLDAENEVLQ--LQQTLFSMKAIQKQCETLQKNKKQLKQEVVNLKSYMERnmLERGKAEWHKLLIEERAR---KEIEEKL 1214
Cdd:PRK11281 53 LLEAEDKLVQqdLEQTLALLDKIDRQKEETEQLKQQLAQAPAKLRQAQAE--LEALKDDNDEETRETLSTlslRQLESRL 130
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 1215 NE---AILTLQKQAAVSHEQLVQLRednTTSIKTQMELT-----IKDLESEISRIKTSQADFNKTELERYK-ELYLEEvk 1285
Cdd:PRK11281 131 AQtldQLQNAQNDLAEYNSQLVSLQ---TQPERAQAALYansqrLQQIRNLLKGGKVGGKALRPSQRVLLQaEQALLN-- 205
|
170 180
....*....|....*....|....
gi 149363642 1286 vresLSNELSRTNemiAEVSTQLT 1309
Cdd:PRK11281 206 ----AQNDLQRKS---LEGNTQLQ 222
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
766-946 |
9.00e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 40.13 E-value: 9.00e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 766 QERNDAQKQLSEEQDARilqdQILTSKQKELEMARKKMNSEISHRHQKEKDLFHEDCMLQEEIALLRLEIDTIKNQNKQK 845
Cdd:COG4942 27 AELEQLQQEIAELEKEL----AALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQ 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149363642 846 EKKYFEDIEAVKEKNDNLQKIIKLNEETLTETI--LQYSGQLNN-----------LTAENKILNSELENGKQNQERLEIE 912
Cdd:COG4942 103 KEELAELLRALYRLGRQPPLALLLSPEDFLDAVrrLQYLKYLAParreqaeelraDLAELAALRAELEAERAELEALLAE 182
|
170 180 190
....*....|....*....|....*....|....
gi 149363642 913 MESYRCRLAAAVRdcDQSQTARDLKLDFQRTRQE 946
Cdd:COG4942 183 LEEERAALEALKA--ERQKLLARLEKELAELAAE 214
|
|
| |
