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Conserved domains on  [gi|6978727|ref|NP_036972|]
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cytochrome c, testis-specific [Rattus norvegicus]

Protein Classification

c-type cytochrome( domain architecture ID 10007442)

c-type cytochrome is an electron carrier protein that contains one or more heme groups

CATH:  1.10.760.10
Gene Ontology:  GO:0020037|GO:0009055|GO:0046872
PubMed:  31252007|22723177|18568041|12594933|10647174|10395550
SCOP:  3000815

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Cyc7 COG3474
Cytochrome c2 [Energy production and conversion];
2-101 3.47e-57

Cytochrome c2 [Energy production and conversion];


:

Pssm-ID: 442697 [Multi-domain]  Cd Length: 101  Bit Score: 171.60  E-value: 3.47e-57
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6978727    2 GDAEAGKKIFIQKCAQCHTVEKGGKHKTGPNLWGLFGRKTGQAPGFSYTDANKNKGVIWTEETLMEYLENPKKYIPGTKM 81
Cdd:COG3474   1 GDAAAGEKLFNRKCAACHSVDGGAGNRVGPNLNGVVGRKAGSVEGFAYSDALKASGLVWDEETLDAWLADPKAFVPGTKM 80

                        90       100
                ....*....|....*....|
gi 6978727   82 IFAGIKKKSEREDLIQYLKE 101
Cdd:COG3474  81 PFAGLKDPEDRADLIAYLKT 100
 
Name Accession Description Interval E-value
Cyc7 COG3474
Cytochrome c2 [Energy production and conversion];
2-101 3.47e-57

Cytochrome c2 [Energy production and conversion];


Pssm-ID: 442697 [Multi-domain]  Cd Length: 101  Bit Score: 171.60  E-value: 3.47e-57
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6978727    2 GDAEAGKKIFIQKCAQCHTVEKGGKHKTGPNLWGLFGRKTGQAPGFSYTDANKNKGVIWTEETLMEYLENPKKYIPGTKM 81
Cdd:COG3474   1 GDAAAGEKLFNRKCAACHSVDGGAGNRVGPNLNGVVGRKAGSVEGFAYSDALKASGLVWDEETLDAWLADPKAFVPGTKM 80

                        90       100
                ....*....|....*....|
gi 6978727   82 IFAGIKKKSEREDLIQYLKE 101
Cdd:COG3474  81 PFAGLKDPEDRADLIAYLKT 100
PTZ00048 PTZ00048
cytochrome c; Provisional
 2-104 3.20e-53

cytochrome c; Provisional


Pssm-ID: 185414  Cd Length: 115  Bit Score: 161.95  E-value: 3.20e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6978727     2 GDAEAGKKIFIQKCAQCHTVEKGGKHKTGPNLWGLFGRKTGqAPGFSYTDANKNKGVIWTEETLMEYLENPKKYIPGTKM 81
Cdd:PTZ00048  13 GDAKKGAKLFKAKCAQCHTINKGGAVKQGPNLHGFYGRKSG-SADFPYSDANKNSGIVWSDKHLFEYLVNPKLYIPGTKM 91

                         90       100
                 ....*....|....*....|...
gi 6978727    82 IFAGIKKKSEREDLIQYLKEATS 104
Cdd:PTZ00048  92 VFAGIKKEKERADLIAYLKEASS 114
Cytochrom_C pfam00034
Cytochrome c; The Pfam entry does not include all Prosite members. The cytochrome 556 and ...
 5-100 1.77e-14

Cytochrome c; The Pfam entry does not include all Prosite members. The cytochrome 556 and cytochrome c' families are not included. All these are now in a new clan together. The C-terminus of DUF989, pfam06181, has now been merged into this family.


Pssm-ID: 459641 [Multi-domain]  Cd Length: 89  Bit Score: 62.94  E-value: 1.77e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6978727      5 EAGKKIFIQKCAQCHTVEKGGKHKTGPNLWGLFGRKTGQAPGFSYTDANKNKGVIWteetlmeyleNPKKYIPGTKMIFA 84
Cdd:pfam00034   1 ARGKKLFAANCAACHGVNGEGAGAGGPDLAGLAARYPGDALGAIRENKHAIGGGGV----------DRAGGPPGTGMPAF 70

                          90
                  ....*....|....*.
gi 6978727     85 GIKKKSEREDLIQYLK 100
Cdd:pfam00034  71 DGLTDEEIADLVAYLL 86
CxxCH_TIGR02603 TIGR02603
putative heme-binding domain, Pirellula/Verrucomicrobium type; This model represents a domain ...
 2-41 9.77e-05

putative heme-binding domain, Pirellula/Verrucomicrobium type; This model represents a domain limited to very few species but expanded into large paralogous families in some species that conain it. We find it in over 20 copies each in Pirellula sp. strain 1 (phylum Planctomycetes) and Verrucomicrobium spinosum DSM 4136 (phylum Verrucomicrobia), and no matches above trusted cutoff an any other species so far. This domain, about 140 amino acids long, contains an absolutely conserved motif CxxCH, the cytochrome c family heme-binding site signature (PS00190).


Pssm-ID: 274224  Cd Length: 133  Bit Score: 38.49  E-value: 9.77e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 6978727      2 GDAEAGKKIFIQKCAQCHTVeKGGKHKTGPNLWGlFGRKT 41
Cdd:TIGR02603   1 GDAARGKAVFAKVCYLCHRI-GGQGVDFGPNLTT-VGTKG 38
 
Name Accession Description Interval E-value
Cyc7 COG3474
Cytochrome c2 [Energy production and conversion];
2-101 3.47e-57

Cytochrome c2 [Energy production and conversion];


Pssm-ID: 442697 [Multi-domain]  Cd Length: 101  Bit Score: 171.60  E-value: 3.47e-57
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6978727    2 GDAEAGKKIFIQKCAQCHTVEKGGKHKTGPNLWGLFGRKTGQAPGFSYTDANKNKGVIWTEETLMEYLENPKKYIPGTKM 81
Cdd:COG3474   1 GDAAAGEKLFNRKCAACHSVDGGAGNRVGPNLNGVVGRKAGSVEGFAYSDALKASGLVWDEETLDAWLADPKAFVPGTKM 80

                        90       100
                ....*....|....*....|
gi 6978727   82 IFAGIKKKSEREDLIQYLKE 101
Cdd:COG3474  81 PFAGLKDPEDRADLIAYLKT 100
PTZ00048 PTZ00048
cytochrome c; Provisional
 2-104 3.20e-53

cytochrome c; Provisional


Pssm-ID: 185414  Cd Length: 115  Bit Score: 161.95  E-value: 3.20e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6978727     2 GDAEAGKKIFIQKCAQCHTVEKGGKHKTGPNLWGLFGRKTGqAPGFSYTDANKNKGVIWTEETLMEYLENPKKYIPGTKM 81
Cdd:PTZ00048  13 GDAKKGAKLFKAKCAQCHTINKGGAVKQGPNLHGFYGRKSG-SADFPYSDANKNSGIVWSDKHLFEYLVNPKLYIPGTKM 91

                         90       100
                 ....*....|....*....|...
gi 6978727    82 IFAGIKKKSEREDLIQYLKEATS 104
Cdd:PTZ00048  92 VFAGIKKEKERADLIAYLKEASS 114
PTZ00405 PTZ00405
cytochrome c; Provisional
 2-100 3.84e-45

cytochrome c; Provisional


Pssm-ID: 173596  Cd Length: 114  Bit Score: 141.71  E-value: 3.84e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6978727     2 GDAEAGKKIFIQKCAQCHTVEKGGKHKTGPNLWGLFGRKTGQAPGFSYTDANKNKGVIWTEETLMEYLENPKKYIPGTKM 81
Cdd:PTZ00405  12 GDAERGEKLFKGRAAQCHTATKGGSNGVGPNLFGIVNRKSGTVEGFAYSKANADSGVIWTPEVLDVYLENPKKFMPGTKM 91

                         90
                 ....*....|....*....
gi 6978727    82 IFAGIKKKSEREDLIQYLK 100
Cdd:PTZ00405  92 SFAGIKKPQERADVIAYLE 110
Cytochrom_C pfam00034
Cytochrome c; The Pfam entry does not include all Prosite members. The cytochrome 556 and ...
 5-100 1.77e-14

Cytochrome c; The Pfam entry does not include all Prosite members. The cytochrome 556 and cytochrome c' families are not included. All these are now in a new clan together. The C-terminus of DUF989, pfam06181, has now been merged into this family.


Pssm-ID: 459641 [Multi-domain]  Cd Length: 89  Bit Score: 62.94  E-value: 1.77e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6978727      5 EAGKKIFIQKCAQCHTVEKGGKHKTGPNLWGLFGRKTGQAPGFSYTDANKNKGVIWteetlmeyleNPKKYIPGTKMIFA 84
Cdd:pfam00034   1 ARGKKLFAANCAACHGVNGEGAGAGGPDLAGLAARYPGDALGAIRENKHAIGGGGV----------DRAGGPPGTGMPAF 70

                          90
                  ....*....|....*.
gi 6978727     85 GIKKKSEREDLIQYLK 100
Cdd:pfam00034  71 DGLTDEEIADLVAYLL 86
CccA COG2010
Cytochrome c, mono- and diheme variants [Energy production and conversion];
3-100 3.10e-06

Cytochrome c, mono- and diheme variants [Energy production and conversion];


Pssm-ID: 441613 [Multi-domain]  Cd Length: 169  Bit Score: 43.40  E-value: 3.10e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6978727    3 DAEAGKKIFIQKCAQCHTVEKGGKHKTGPNLwglfgrktgqapgfsyTDANKNKGviwTEETLMEYLENPkkyIPGTKMI 82
Cdd:COG2010  88 ALARGKALYEQNCAACHGADGKGGLGAAPNL----------------TDDALYGG---DPEALVETILNG---RPGGAMP 145

                        90
                ....*....|....*....
gi 6978727   83 -FAGIKKKSEREDLIQYLK 100
Cdd:COG2010 146 aFGGQLSDEEIAALAAYLR 164
TsdA COG3258
Thiosulfate dehydrogenase TsdA, contains C-terminal cytochrome c domain [Inorganic ion ...
 2-53 1.35e-05

Thiosulfate dehydrogenase TsdA, contains C-terminal cytochrome c domain [Inorganic ion transport and metabolism];


Pssm-ID: 442489 [Multi-domain]  Cd Length: 216  Bit Score: 41.76  E-value: 1.35e-05
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*..
gi 6978727    2 GDAEAGKKIFIQKCAQCHTVE-KGGKHKTG----PNLWGlfgrktgqapGFSYTDAN 53
Cdd:COG3258 115 ADVERGKALYAERCASCHGADgEGQGRADGqygfPPLWG----------GDSYNDGA 161
Cytochrome_CBB3 pfam13442
Cytochrome C oxidase, cbb3-type, subunit III;
2-99 6.36e-05

Cytochrome C oxidase, cbb3-type, subunit III;


Pssm-ID: 463879 [Multi-domain]  Cd Length: 67  Bit Score: 37.77  E-value: 6.36e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6978727      2 GDAEAGKKIFIQKCAQCHtvekgGKHKTGPNlwgLFGRKtgqapgfsytdanknkgviWTEETLMEYLENPKKYIPGtkm 81
Cdd:pfam13442   1 AAAAAGEALYAANCASCH-----GTGGAGPS---LAGRA-------------------LPPEALVDIIRNGKGAMPA--- 50

                          90
                  ....*....|....*...
gi 6978727     82 iFAGIKKKSEREDLIQYL 99
Cdd:pfam13442  51 -FGGDLSDEELEALAAYL 67
CxxCH_TIGR02603 TIGR02603
putative heme-binding domain, Pirellula/Verrucomicrobium type; This model represents a domain ...
 2-41 9.77e-05

putative heme-binding domain, Pirellula/Verrucomicrobium type; This model represents a domain limited to very few species but expanded into large paralogous families in some species that conain it. We find it in over 20 copies each in Pirellula sp. strain 1 (phylum Planctomycetes) and Verrucomicrobium spinosum DSM 4136 (phylum Verrucomicrobia), and no matches above trusted cutoff an any other species so far. This domain, about 140 amino acids long, contains an absolutely conserved motif CxxCH, the cytochrome c family heme-binding site signature (PS00190).


Pssm-ID: 274224  Cd Length: 133  Bit Score: 38.49  E-value: 9.77e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 6978727      2 GDAEAGKKIFIQKCAQCHTVeKGGKHKTGPNLWGlFGRKT 41
Cdd:TIGR02603   1 GDAARGKAVFAKVCYLCHRI-GGQGVDFGPNLTT-VGTKG 38
psbV CHL00133
photosystem II cytochrome c550; Validated
 7-75 4.53e-04

photosystem II cytochrome c550; Validated


Pssm-ID: 177055  Cd Length: 163  Bit Score: 37.36  E-value: 4.53e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 6978727     7 GKKIFIQKCAQCHTvekGGKHKTGPNLwglfgrktGQAPGfSYTDANKNKGVIwteETLMEYLENPKKY 75
Cdd:CHL00133  55 GKRLFNASCGACHV---GGITKTNPNV--------GLDPE-ALSLATPPRDNI---EALVDYMKNPTTY 108
CytC553 COG2863
Cytochrome c553 [Energy production and conversion];
2-36 5.27e-04

Cytochrome c553 [Energy production and conversion];


Pssm-ID: 442110 [Multi-domain]  Cd Length: 98  Bit Score: 36.25  E-value: 5.27e-04
                        10        20        30
                ....*....|....*....|....*....|....*.
gi 6978727    2 GDAEAGKKiFIQKCAQCHTVE-KGGKHKTGPNLWGL 36
Cdd:COG2863  13 GDAARGKA-YAAACAACHGADgEGNPGGGAPRLAGQ 47
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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