|
Name |
Accession |
Description |
Interval |
E-value |
| PLN02287 |
PLN02287 |
3-ketoacyl-CoA thiolase |
9-430 |
0e+00 |
|
3-ketoacyl-CoA thiolase
Pssm-ID: 215161 [Multi-domain] Cd Length: 452 Bit Score: 610.23 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 9 SAMHRLQVVLGHLAGRPESSSALQAAPCSASFPQASAS------DVVVVHGRRTPIGRAGRGGFKDTTPDELLSAVLTAV 82
Cdd:PLN02287 3 KAINRQRVLLRHLRPSSSEPSSLSASACAAGDSAAYHRttafgdDVVIVAAYRTPICKAKRGGFKDTYPDDLLAPVLKAV 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 83 LQDVKLKPECLGDISVGNVLEPGAG-AVMARIAQFLSGIPETVPLSAVNRQCSSGLQAVANIAGGIRNGSYDIGMACGVE 161
Cdd:PLN02287 83 VEKTGLNPSEVGDIVVGTVLAPGSQrANECRMAAFYAGFPETVPVRTVNRQCSSGLQAVADVAAAIKAGFYDIGIGAGVE 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 162 SMSLSNRGNPGNISSRLLESDKARDCLIPMGITSENVAERFGISRQKQDAFALASQQKAASAQSKGCFRAEIVPVTTTVL 241
Cdd:PLN02287 163 SMTTNPMAWEGGVNPRVESFSQAQDCLLPMGITSENVAERFGVTREEQDQAAVESHRKAAAATASGKFKDEIVPVHTKIV 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 242 DDK-GDRKTITVSQDEGVRPSTTMEGLAKLKPAFKDGGSTTAGNSSQVSDGAAAVLLARRSKAEELGLPILGVLRSYAVV 320
Cdd:PLN02287 243 DPKtGEEKPIVISVDDGIRPNTTLADLAKLKPVFKKNGTTTAGNSSQVSDGAGAVLLMKRSVAMQKGLPILGVFRSFAAV 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 321 GVPPDIMGIGPAYAIPAALQKAGLTVNDIDIFEINEAFASQALYCVEKLGIPAEKVNPLGGAIALGHPLGCTGARQVVTL 400
Cdd:PLN02287 323 GVDPAVMGIGPAVAIPAAVKAAGLELDDIDLFEINEAFASQFVYCCKKLGLDPEKVNVNGGAIALGHPLGATGARCVATL 402
|
410 420 430
....*....|....*....|....*....|.
gi 2074188883 401 LNELKRRGRRA-YGVVSMCIGTGMGAAAVFE 430
Cdd:PLN02287 403 LHEMKRRGKDCrFGVVSMCIGTGMGAAAVFE 433
|
|
| thiolase |
cd00751 |
Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of ... |
49-431 |
0e+00 |
|
Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and eukaryotes (cytosol, microbodies and mitochondria). There are 2 functional different classes: thiolase-I (3-ketoacyl-CoA thiolase) and thiolase-II (acetoacetyl-CoA thiolase). Thiolase-I can cleave longer fatty acid molecules and plays an important role in the beta-oxidative degradation of fatty acids. Thiolase-II has a high substrate specificity. Although it can cleave acetoacyl-CoA, its main function is the synthesis of acetoacyl-CoA from two molecules of acetyl-CoA, which gives it importance in several biosynthetic pathways.
Pssm-ID: 238383 [Multi-domain] Cd Length: 386 Bit Score: 547.85 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 49 VVVHGRRTPIGRAGrGGFKDTTPDELLSAVLTAVLQDVKLKPECLGDISVGNVLEPGAGAVMARIAQFLSGIPETVPLSA 128
Cdd:cd00751 1 VIVSAVRTPIGRFG-GALKDVSADDLGAAVIKALLERAGLDPEEVDDVIMGNVLQAGEGQNPARQAALLAGLPESVPATT 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 129 VNRQCSSGLQAVANIAGGIRNGSYDIGMACGVESMSLSNRGNPGNISSRLLESDK----------ARDCLIPMGITSENV 198
Cdd:cd00751 80 VNRVCGSGLQAVALAAQSIAAGEADVVVAGGVESMSRAPYLLPKARRGGRLGLNTldgmlddgltDPFTGLSMGITAENV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 199 AERFGISRQKQDAFALASQQKAASAQSKGCFRAEIVPVTTtvlddKGDRKTITVSQDEGVRPSTTMEGLAKLKPAFKDGG 278
Cdd:cd00751 160 AEKYGISREEQDEFALRSHQRAAAAQEAGRFKDEIVPVEV-----PGRKGPVVVDRDEGPRPDTTLEKLAKLKPAFKKDG 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 279 STTAGNSSQVSDGAAAVLLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAYAIPAALQKAGLTVNDIDIFEINEAF 358
Cdd:cd00751 235 TVTAGNASGINDGAAAVLLMSEEKAKELGLKPLARIVGYAVAGVDPAIMGIGPVPAIPKALKRAGLTLDDIDLIEINEAF 314
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2074188883 359 ASQALYCVEKLGIPAEKVNPLGGAIALGHPLGCTGARQVVTLLNELKRRGRRaYGVVSMCIGTGMGAAAVFEY 431
Cdd:cd00751 315 AAQALACLKELGLDPEKVNVNGGAIALGHPLGASGARIVVTLLHELKRRGGR-YGLATMCIGGGQGAAMVIER 386
|
|
| PaaJ |
COG0183 |
Acetyl-CoA acetyltransferase [Lipid transport and metabolism]; Acetyl-CoA acetyltransferase is ... |
46-430 |
0e+00 |
|
Acetyl-CoA acetyltransferase [Lipid transport and metabolism]; Acetyl-CoA acetyltransferase is part of the Pathway/BioSystem: Fatty acid biosynthesis
Pssm-ID: 439953 [Multi-domain] Cd Length: 391 Bit Score: 509.61 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 46 SDVVVVHGRRTPIGRAGrGGFKDTTPDELLSAVLTAVLQDVKLKPECLGDISVGNVLEPGAGAVMARIAQFLSGIPETVP 125
Cdd:COG0183 2 REVVIVDAVRTPFGRFG-GALADVRADDLGAAVIKALLERAGLDPEAVDDVILGCVLQAGQGQNPARQAALLAGLPESVP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 126 LSAVNRQCSSGLQAVANIAGGIRNGSYDIGMACGVESMS----LSNRGNPGNISSRLLESDKARDCL------IPMGITS 195
Cdd:COG0183 81 AVTVNRVCGSGLQAVALAAQAIAAGDADVVIAGGVESMSrapmLLPKARWGYRMNAKLVDPMINPGLtdpytgLSMGETA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 196 ENVAERFGISRQKQDAFALASQQKAASAQSKGCFRAEIVPVTTtvlddKGDRKTITVSQDEGVRPSTTMEGLAKLKPAFK 275
Cdd:COG0183 161 ENVAERYGISREEQDAFALRSHQRAAAAIAAGRFDDEIVPVEV-----PDRKGEVVVDRDEGPRPDTTLEKLAKLKPAFK 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 276 DGGSTTAGNSSQVSDGAAAVLLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAYAIPAALQKAGLTVNDIDIFEIN 355
Cdd:COG0183 236 KDGTVTAGNASGINDGAAALLLMSEEAAKELGLKPLARIVAYAVAGVDPEIMGIGPVPATRKALARAGLTLDDIDLIEIN 315
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2074188883 356 EAFASQALYCVEKLGIPAEKVNPLGGAIALGHPLGCTGARQVVTLLNELKRRGRRaYGVVSMCIGTGMGAAAVFE 430
Cdd:COG0183 316 EAFAAQVLAVLRELGLDPDKVNVNGGAIALGHPLGASGARILVTLLHELERRGGR-YGLATMCIGGGQGIALIIE 389
|
|
| AcCoA-C-Actrans |
TIGR01930 |
acetyl-CoA acetyltransferases; This model represents a large family of enzymes which catalyze ... |
50-430 |
2.00e-168 |
|
acetyl-CoA acetyltransferases; This model represents a large family of enzymes which catalyze the thiolysis of a linear fatty acid CoA (or acetoacetyl-CoA) using a second CoA molecule to produce acetyl-CoA and a CoA-ester product two carbons shorter (or, alternatively, the condensation of two molecules of acetyl-CoA to produce acetoacetyl-CoA and CoA). This enzyme is also known as "thiolase", "3-ketoacyl-CoA thiolase", "beta-ketothiolase" and "Fatty oxidation complex beta subunit". When catalyzing the degradative reaction on fatty acids the corresponding EC number is 2.3.1.16. The condensation reaction corresponds to 2.3.1.9. Note that the enzymes which catalyze the condensation are generally not involved in fatty acid biosynthesis, which is carried out by a decarboxylating condensation of acetyl and malonyl esters of acyl carrier proteins. Rather, this activity may produce acetoacetyl-CoA for pathways such as IPP biosynthesis in the absence of sufficient fatty acid oxidation. [Fatty acid and phospholipid metabolism, Other]
Pssm-ID: 273881 [Multi-domain] Cd Length: 385 Bit Score: 477.88 E-value: 2.00e-168
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 50 VVHGRRTPIGRAGrGGFKDTTPDELLSAVLTAVLQDVKLKPECLGDISVGNVLEPGAGAVMARIAQFLSGIPETVPLSAV 129
Cdd:TIGR01930 1 IVAAARTPIGKFG-GSLKDVSAEDLGAAVIKELLERNPLDPELIDDVIFGNVLQAGEQQNIARQAALLAGLPESVPAYTV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 130 NRQCSSGLQAVANIAGGIRNGSYDIGMACGVESMS---------LSNRGNPGNISSR--LLESDKARDCLIPMGITSENV 198
Cdd:TIGR01930 80 NRQCASGLQAVILAAQLIRAGEADVVVAGGVESMSrvpygvprsLRWGVKPGNAELEdaRLKDLTDANTGLPMGVTAENL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 199 AERFGISRQKQDAFALASQQKAASAQSKGCFRAEIVPVTttvldDKGDRKTITVSQDEGVRPSTTMEGLAKLKPAFKDGG 278
Cdd:TIGR01930 160 AKKYGISREEQDEYALRSHQRAAKAWEEGLFKDEIVPVT-----VKGRKGPVTVSSDEGIRPNTTLEKLAKLKPAFDPDG 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 279 STTAGNSSQVSDGAAAVLLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAYAIPAALQKAGLTVNDIDIFEINEAF 358
Cdd:TIGR01930 235 TVTAGNSSPLNDGAAALLLMSEEKAKELGLTPLARIVSFAVAGVDPEIMGLGPVPAIPKALKKAGLSISDIDLFEINEAF 314
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2074188883 359 ASQALYCVEKLGIPAEKVNPLGGAIALGHPLGCTGARQVVTLLNELKRRGRRaYGVVSMCIGTGMGAAAVFE 430
Cdd:TIGR01930 315 AAQVLACIKELGLDLEKVNVNGGAIALGHPLGASGARIVTTLLHELKRRGGR-YGLATMCIGGGQGAAVILE 385
|
|
| PRK05790 |
PRK05790 |
putative acyltransferase; Provisional |
46-432 |
2.64e-156 |
|
putative acyltransferase; Provisional
Pssm-ID: 180261 [Multi-domain] Cd Length: 393 Bit Score: 447.29 E-value: 2.64e-156
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 46 SDVVVVHGRRTPIGRAGrGGFKDTTPDELLSAVLTAVLQDVKLKPECLGDISVGNVLEPGAGAVMARIAQFLSGIPETVP 125
Cdd:PRK05790 2 KDVVIVSAARTPIGKFG-GALKDVSAVELGAIVIKAALERAGVPPEQVDEVIMGQVLQAGAGQNPARQAALKAGLPVEVP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 126 LSAVNRQCSSGLQAVANIAGGIRNGSYDIGMACGVESMSL-------SNRGNP-GNISsrlLESDKARDCL------IPM 191
Cdd:PRK05790 81 ALTINKVCGSGLKAVALAAQAIRAGDADIVVAGGQESMSQaphvlpgSRWGQKmGDVE---LVDTMIHDGLtdafngYHM 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 192 GITSENVAERFGISRQKQDAFALASQQKAASAQSKGCFRAEIVPVTttVLDDKGDrkTITVSQDEGVRPSTTMEGLAKLK 271
Cdd:PRK05790 158 GITAENLAEQYGITREEQDEFALASQQKAEAAIKAGRFKDEIVPVT--IKQRKGD--PVVVDTDEHPRPDTTAESLAKLR 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 272 PAFKDGGSTTAGNSSQVSDGAAAVLLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAYAIPAALQKAGLTVNDIDI 351
Cdd:PRK05790 234 PAFDKDGTVTAGNASGINDGAAAVVVMSEAKAKELGLTPLARIVSYAVAGVDPAIMGIGPVPAIRKALEKAGWSLADLDL 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 352 FEINEAFASQALYCVEKLGIPAEKVNPLGGAIALGHPLGCTGARQVVTLLNELKRRGRRaYGVVSMCIGTGMGAAAVFEY 431
Cdd:PRK05790 314 IEINEAFAAQALAVEKELGLDPEKVNVNGGAIALGHPIGASGARILVTLLHEMKRRGAK-KGLATLCIGGGQGVALIVER 392
|
.
gi 2074188883 432 P 432
Cdd:PRK05790 393 P 393
|
|
| PRK09052 |
PRK09052 |
acetyl-CoA C-acyltransferase; |
47-430 |
5.21e-145 |
|
acetyl-CoA C-acyltransferase;
Pssm-ID: 181626 [Multi-domain] Cd Length: 399 Bit Score: 419.02 E-value: 5.21e-145
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 47 DVVVVHGRRTPIGRAGRGGFKDTTPDELLSAVLTAVLQDVK-LKPECLGDISVGNVL-EPGAGAVMARIAQFLSGIPETV 124
Cdd:PRK09052 7 DAYIVAATRTPVGKAPRGMFKNTRPDDLLAHVLRSAVAQVPgLDPKLIEDAIVGCAMpEAEQGLNVARIGALLAGLPNSV 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 125 PLSAVNRQCSSGLQAVANIAGGIRNGSYDIGMACGVESMSLSN-RGNPGNISSRLLESDKARDCLIPMGITSENVAERFG 203
Cdd:PRK09052 87 GGVTVNRFCASGLQAVAMAADRIRVGEADVMIAAGVESMSMVPmMGNKPSMSPAIFARDENVGIAYGMGLTAEKVAEQWK 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 204 ISRQKQDAFALASQQKAASAQSKGCFRAEIVP--VTTTVLDDKG---DRKTITVSQDEGVRPSTTMEGLAKLKPAFKDGG 278
Cdd:PRK09052 167 VSREDQDAFALESHQKAIAAQQAGEFKDEITPyeITERFPDLATgevDVKTRTVDLDEGPRADTSLEGLAKLKPVFANKG 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 279 STTAGNSSQVSDGAAAVLLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAYAIPAALQKAGLTVNDIDIFEINEAF 358
Cdd:PRK09052 247 SVTAGNSSQTSDGAGAVILVSEKALKQFNLTPLARFVSFAVAGVPPEIMGIGPIEAIPAALKQAGLKQDDLDWIELNEAF 326
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2074188883 359 ASQALYCVEKLGIPAEKVNPLGGAIALGHPLGCTGARQVVTLLNELKRRGRRaYGVVSMCIGTGMGAAAVFE 430
Cdd:PRK09052 327 AAQSLAVIRDLGLDPSKVNPLGGAIALGHPLGATGAIRTATVVHGLRRTNLK-YGMVTMCVGTGMGAAGIFE 397
|
|
| PRK07661 |
PRK07661 |
acetyl-CoA C-acetyltransferase; |
49-430 |
3.84e-137 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 181072 [Multi-domain] Cd Length: 391 Bit Score: 398.74 E-value: 3.84e-137
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 49 VVVHGRRTPIGRAGRGGFKDTTPDELLSAVLTAVLQDVKLKPECLGDISVGNVL-EPGAGAVMARIAQFLSGIPETVPLS 127
Cdd:PRK07661 5 VIVAGARTPVGKAKKGSLKTVRPDDLGALVVKETLKRAGNYEGPIDDLIIGCAMpEAEQGLNMARNIGALAGLPYTVPAI 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 128 AVNRQCSSGLQAVANIAGGIRNGSYDIGMACGVESMSLSNRGnpGNI---SSRLLESdkARDCLIPMGITSENVAERFGI 204
Cdd:PRK07661 85 TINRYCSSGLQSIAYGAERIMLGHSEAVIAGGAESMSLVPMM--GHVvrpNPRLVEA--APEYYMGMGHTAEQVAVKYGI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 205 SRQKQDAFALASQQKAASAQSKGCFRAEIVPVTTTVL----DDKGDRKTITVSQDEGVRPSTTMEGLAKLKPAFKDGGST 280
Cdd:PRK07661 161 SREDQDAFAVRSHQRAAKALAEGKFADEIVPVDVTLRtvgeNNKLQEETITFSQDEGVRADTTLEILGKLRPAFNVKGSV 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 281 TAGNSSQVSDGAAAVLLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAYAIPAALQKAGLTVNDIDIFEINEAFAS 360
Cdd:PRK07661 241 TAGNSSQMSDGAAAVLLMDREKAESDGLKPLAKFRSFAVAGVPPEVMGIGPIAAIPKALKLAGLELSDIGLFELNEAFAS 320
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 361 QALYCVEKLGIPAEKVNPLGGAIALGHPLGCTGARQVVTLLNELKRRGRRaYGVVSMCIGTGMGAAAVFE 430
Cdd:PRK07661 321 QSIQVIRELGLDEEKVNVNGGAIALGHPLGCTGAKLTLSLIHEMKRRNEQ-FGIVTMCIGGGMGAAGVFE 389
|
|
| PRK09051 |
PRK09051 |
beta-ketothiolase BktB; |
44-430 |
7.68e-122 |
|
beta-ketothiolase BktB;
Pssm-ID: 181625 [Multi-domain] Cd Length: 394 Bit Score: 359.66 E-value: 7.68e-122
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 44 SASDVVVVHGRRTPIGRAGrGGFKDTTPDELLSAVLTAVLQDVKLKPECLGDISVGNVL--EPgAGAVMARIAQFLSGIP 121
Cdd:PRK09051 1 MMREVVVVSGVRTAIGTFG-GSLKDVAPTDLGATVVREALARAGVDPDQVGHVVFGHVIptEP-RDMYLSRVAAINAGVP 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 122 ETVPLSAVNRQCSSGLQAVANIAGGIRNGSYDIGMACGVESMSLSNRGNPGNISSRLLESDKARDCL----------IPM 191
Cdd:PRK09051 79 QETPAFNVNRLCGSGLQAIVSAAQAILLGDADVAIGGGAESMSRAPYLLPAARWGARMGDAKLVDMMvgalhdpfgtIHM 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 192 GITSENVAERFGISRQKQDAFALASQQKAASAQSKGCFRAEIVPVTTtvlddKGDRKTITVSQDEGVRPSTTMEGLAKLK 271
Cdd:PRK09051 159 GVTAENVAAKYGISREAQDALALESHRRAAAAIAAGYFKDQIVPVEI-----KTRKGEVVFDTDEHVRADTTLEDLAKLK 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 272 PAF-KDGGSTTAGNSSQVSDGAAAVLLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAYAIPAALQKAGLTVNDID 350
Cdd:PRK09051 234 PVFkKENGTVTAGNASGINDGAAAVVLAEADAAEARGLKPLARLVGYAHAGVDPEYMGIGPVPATQKALERAGLTVADLD 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 351 IFEINEAFASQALYCVEKLGIPAEKVNPLGGAIALGHPLGCTGARQVVTLLNELKRRGRRaYGVVSMCIGTGMGAAAVFE 430
Cdd:PRK09051 314 VIEANEAFAAQACAVTRELGLDPAKVNPNGSGISLGHPVGATGAIITVKALYELQRIGGR-YALVTMCIGGGQGIAAIFE 392
|
|
| PRK06205 |
PRK06205 |
acetyl-CoA C-acetyltransferase; |
46-430 |
3.36e-114 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 235741 [Multi-domain] Cd Length: 404 Bit Score: 340.43 E-value: 3.36e-114
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 46 SDVVVVHGRRTPIGRAGrGGFKDTTPDELLSAVLTAVLQDVKLKPECLGDISVGNVLEPGAGAVMARIAQFLSGIPETVP 125
Cdd:PRK06205 2 RDAVICEPVRTPVGRFG-GAFKDVPAEELAATVIRALVERTGIDPARIDDVIFGQGYPNGEAPAIGRVAALDAGLPVTVP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 126 LSAVNRQCSSGLQAVANIAGGIRNGSYDIGMACGVESMS----------LSNRGNPGNISSRLlesDKARDCL------I 189
Cdd:PRK06205 81 GMQLDRRCGSGLQAVITAAMQVQTGAADVVIAGGAESMSnvefyttdmrWGVRGGGVQLHDRL---ARGRETAggrrfpV 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 190 PMGI--TSENVAERFGISRQKQDAFALASQQKAASAQSKGCFRAEIVPVTttVLDDKGDrkTITVSQDEGVRPSTTMEGL 267
Cdd:PRK06205 158 PGGMieTAENLRREYGISREEQDALAVRSHQRAVAAQEAGRFDDEIVPVT--VPQRKGD--PTVVDRDEHPRADTTLESL 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 268 AKLKP--AFKDGGST-TAGNSSQVSDGAAAVLLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAYAIPAALQKAGL 344
Cdd:PRK06205 234 AKLRPimGKQDPEATvTAGNASGQNDAAAACLVTTEDKAEELGLRPLARLVSWAVAGVEPSRMGIGPVPATEKALARAGL 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 345 TVNDIDIFEINEAFASQALYCVEKLGIPA---EKVNPLGGAIALGHPLGCTGARQVVTLLNELKRRGRRaYGVVSMCIGT 421
Cdd:PRK06205 314 TLDDIDLIELNEAFAAQVLAVLKEWGFGAddeERLNVNGSGISLGHPVGATGGRILATLLRELQRRQAR-YGLETMCIGG 392
|
....*....
gi 2074188883 422 GMGAAAVFE 430
Cdd:PRK06205 393 GQGLAAVFE 401
|
|
| PRK07108 |
PRK07108 |
acetyl-CoA C-acyltransferase; |
46-430 |
6.48e-114 |
|
acetyl-CoA C-acyltransferase;
Pssm-ID: 180843 [Multi-domain] Cd Length: 392 Bit Score: 339.44 E-value: 6.48e-114
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 46 SDVVVVHGRRTPIGRAGRGGFKDTTPDELLSAVLTAVLQDVKLKPECLGDISVGNVLEPGA-GAVMARIAQFLSGIPETV 124
Cdd:PRK07108 2 TEAVIVSTARTPLAKSWRGAFNMTHGATLGGHVVQHAVERAKLDPAEVEDVIMGCANPEGAtGANIARQIALRAGLPVTV 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 125 PLSAVNRQCSSGLQAVANIAGGIRNGSYDIGMACGVESMSL-SNRGNPGNISSRLLESDKArDCLIPMGITSENVAERFG 203
Cdd:PRK07108 82 PGMTVNRFCSSGLQTIALAAQRVIAGEGDVFVAGGVESISCvQNEMNRHMLREGWLVEHKP-EIYWSMLQTAENVAKRYG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 204 ISRQKQDAFALASQQKAASAQSKGCFRAEIVPVTTT--VLDDKGDR---KTITVSQDEGVRPSTTMEGLAKLKPAFKdGG 278
Cdd:PRK07108 161 ISKERQDEYGVQSQQRAAAAQAAGRFDDEIVPITVTagVADKATGRlftKEVTVSADEGIRPDTTLEGVSKIRSALP-GG 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 279 STTAGNSSQVSDGAAAVLLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAYAIPAALQKAGLTVNDIDIFEINEAF 358
Cdd:PRK07108 240 VITAGNASQFSDGASACVVMNAKVAEREGLQPLGIFRGFAVAGCEPDEMGIGPVFAVPKLLKQAGLKVDDIDLWELNEAF 319
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2074188883 359 ASQALYCVEKLGIPAEKVNPLGGAIALGHPLGCTGARQVVTLLNELKRRGRRaYGVVSMCIGTGMGAAAVFE 430
Cdd:PRK07108 320 AVQVLYCRDTLGIPMDRLNVNGGAIAVGHPYGVSGARLTGHALIEGKRRGAK-YVVVTMCIGGGQGAAGLFE 390
|
|
| PRK09050 |
PRK09050 |
beta-ketoadipyl CoA thiolase; Validated |
46-430 |
6.08e-112 |
|
beta-ketoadipyl CoA thiolase; Validated
Pssm-ID: 181624 [Multi-domain] Cd Length: 401 Bit Score: 334.61 E-value: 6.08e-112
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 46 SDVVVVHGRRTPIGRAGrGGFKDTTPDELLSAVLTAVLQ-DVKLKPECLGDISVGNVLEPGA-GAVMARIAQFLSGIPET 123
Cdd:PRK09050 2 TEAFICDAIRTPIGRYG-GALSSVRADDLGAVPLKALMArNPGVDWEAVDDVIYGCANQAGEdNRNVARMSALLAGLPVS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 124 VPLSAVNRQCSSGLQAVANIAGGIRNGSYDIGMACGVESMSLSnrgnP---GNISSRLLESDKARDCLI----------- 189
Cdd:PRK09050 81 VPGTTINRLCGSGMDAVGTAARAIKAGEAELMIAGGVESMSRA----PfvmGKADSAFSRQAEIFDTTIgwrfvnplmka 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 190 -----PMGITSENVAERFGISRQKQDAFALASQQKAASAQSKGCFRAEIVPVttTVLDDKGDrkTITVSQDEGVRPSTTM 264
Cdd:PRK09050 157 qygvdSMPETAENVAEDYNISRADQDAFALRSQQRAAAAQAAGFLAEEIVPV--TIPQKKGD--PVVVDRDEHPRPETTL 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 265 EGLAKLKPAFKDGGSTTAGNSSQVSDGAAAVLLARRSKAEELGL-PILGVLrSYAVVGVPPDIMGIGPAYAIPAALQKAG 343
Cdd:PRK09050 233 EALAKLKPVFRPDGTVTAGNASGVNDGAAALLLASEAAAKKHGLtPRARIL-GMATAGVEPRIMGIGPAPATRKLLARLG 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 344 LTVNDIDIFEINEAFASQALYCVEKLGIP--AEKVNPLGGAIALGHPLGCTGARQVVTLLNELKRRGRRaYGVVSMCIGT 421
Cdd:PRK09050 312 LTIDQFDVIELNEAFAAQGLAVLRQLGLAddDARVNPNGGAIALGHPLGMSGARLVLTALHQLERTGGR-YALCTMCIGV 390
|
....*....
gi 2074188883 422 GMGAAAVFE 430
Cdd:PRK09050 391 GQGIALAIE 399
|
|
| fadA |
PRK08947 |
3-ketoacyl-CoA thiolase; Reviewed |
47-430 |
3.87e-111 |
|
3-ketoacyl-CoA thiolase; Reviewed
Pssm-ID: 181592 [Multi-domain] Cd Length: 387 Bit Score: 331.93 E-value: 3.87e-111
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 47 DVVVVHGRRTPIGRAGRGGFKDTTPDELLSAVLTAVL-QDVKLKPECLGDISVGNV---LEPGAGavMARIAQFLSGIPE 122
Cdd:PRK08947 3 DVVIVDAIRTPMGRSKGGAFRNVRAEDLSAHLMRSLLaRNPALDPAEIDDIIWGCVqqtLEQGFN--IARNAALLAGIPH 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 123 TVPLSAVNRQCSSGLQAVANIAGGIRNGSYDIGMACGVESMSL--SNRG---NPGNISSrlleSDKARDClipMGITSEN 197
Cdd:PRK08947 81 SVPAVTVNRLCGSSMQALHDAARAIMTGDGDVFLIGGVEHMGHvpMNHGvdfHPGLSKN----VAKAAGM---MGLTAEM 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 198 VAERFGISRQKQDAFALASQQKAASAQSKGCFRAEIVPVTTTvlDDKGDRKTITVsqDEGVRPSTTMEGLAKLKPAFKD- 276
Cdd:PRK08947 154 LGKMHGISREQQDAFAARSHQRAWAATQEGRFKNEIIPTEGH--DADGVLKLFDY--DEVIRPETTVEALAALRPAFDPv 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 277 GGSTTAGNSSQVSDGAAAVLLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAYAIPAALQKAGLTVNDIDIFEINE 356
Cdd:PRK08947 230 NGTVTAGTSSALSDGASAMLVMSESRAKELGLKPRARIRSMAVAGCDPSIMGYGPVPATQKALKRAGLSISDIDVFELNE 309
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2074188883 357 AFASQALYCVEKLGI---PAEKVNPLGGAIALGHPLGCTGARQVVTLLNELKRRGRRaYGVVSMCIGTGMGAAAVFE 430
Cdd:PRK08947 310 AFAAQSLPCLKDLGLldkMDEKVNLNGGAIALGHPLGCSGARISTTLLNLMERKDAQ-FGLATMCIGLGQGIATVFE 385
|
|
| PRK06445 |
PRK06445 |
acetyl-CoA C-acetyltransferase; |
47-430 |
3.87e-109 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 180563 [Multi-domain] Cd Length: 394 Bit Score: 327.45 E-value: 3.87e-109
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 47 DVVVVHGRRTPIGRAG-----RGGFKDTTPDELLSAVLTAVLQDVKLKPECLGDISVGNVLEPGAG-AVMARIAQFLSGI 120
Cdd:PRK06445 3 DVYLVDFARTAFSRFRpkdpqKDVFNNIRPEELAAMLINRLIEKTGIKPEEIDDIITGCALQVGENwLYGGRHPIFLARL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 121 PETVPLSAVNRQCSSGLQAVANIAGGIRNGSYDIGMACGVESMSLSNRG-NPG-NISSRLLESDKARDCLIP----MGIT 194
Cdd:PRK06445 83 PYNIPAMAVDRQCASSLTTVSIGAMEIATGMADIVIAGGVEHMTRTPMGdNPHiEPNPKLLTDPKYIEYDLTtgyvMGLT 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 195 SENVAERFGISRQKQDAFALASQQKAASAQSKGCFRAEIVPVTTTVlddkgDRKTITVSQDEGVRPSTTMEGLAKLKPAF 274
Cdd:PRK06445 163 AEKLAEEAGIKREEMDRWSLRSHQLAAKAIQEGYFKDEILPIEVEV-----EGKKKVVDVDQSVRPDTSLEKLAKLPPAF 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 275 KDGGSTTAGNSSQVSDGAAAVLLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAYAIPAALQKAGLTVNDIDIFEI 354
Cdd:PRK06445 238 KPDGVITAGNSSPLNSGASYVLLMSKKAVKKYGLKPMAKIRSFGFAGVPPAIMGKGPVPASKKALEKAGLSVKDIDLWEI 317
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2074188883 355 NEAFASQALYCVEKLGIPAEKVNPLGGAIALGHPLGCTGARQVVTLLNELKRRGRRaYGVVSMCIGTGMGAAAVFE 430
Cdd:PRK06445 318 NEAFAVVVLYAIKELGLDPETVNIKGGAIAIGHPLGATGARIVGTLARQLQIKGKD-YGVATLCVGGGQGGAVVLE 392
|
|
| PRK07851 |
PRK07851 |
acetyl-CoA C-acetyltransferase; |
47-430 |
8.00e-103 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 181146 [Multi-domain] Cd Length: 406 Bit Score: 311.55 E-value: 8.00e-103
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 47 DVVVVHGRRTPIGRAGRGGFKDTTPDELLSAVLTAVLQDV-KLKPECLGDISVGNVLEPG-AGAVMARIAQFLSGIPeTV 124
Cdd:PRK07851 3 EAVIVSTARSPIGRAFKGSLKDMRPDDLAAQMVRAALDKVpALDPTDIDDLMLGCGLPGGeQGFNMARVVAVLLGYD-FL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 125 PLSAVNRQCSSGLQAVANIAGGIRNGSYDIGMACGVESMSLSNRGN----PGNISSRLLESdKAR--------------- 185
Cdd:PRK07851 82 PGTTVNRYCSSSLQTTRMAFHAIKAGEGDVFISAGVETVSRFAKGNsdslPDTKNPLFAEA-QARtaaraeggaeawhdp 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 186 -------DCLIPMGITSENVAERFGISRQKQDAFALASQQKAASAQSKGCFRAEIVPVTT---TVlddkgdrktitVSQD 255
Cdd:PRK07851 161 redgllpDVYIAMGQTAENVAQLTGISREEQDEWGVRSQNRAEEAIANGFFEREITPVTLpdgTV-----------VSTD 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 256 EGVRPSTTMEGLAKLKPAFKDGGSTTAGNSSQVSDGAAAVLLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAYAI 335
Cdd:PRK07851 230 DGPRAGTTYEKVSQLKPVFRPDGTVTAGNACPLNDGAAAVVIMSDTKARELGLTPLARIVSTGVSGLSPEIMGLGPVEAS 309
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 336 PAALQKAGLTVNDIDIFEINEAFASQALYCVEKLGIPAEKVNPLGGAIALGHPLGCTGARQVVTLLNELKRRGRRaYGVV 415
Cdd:PRK07851 310 KQALARAGMSIDDIDLVEINEAFAAQVLPSARELGIDEDKLNVSGGAIALGHPFGMTGARITTTLLNNLQTHDKT-FGLE 388
|
410
....*....|....*
gi 2074188883 416 SMCIGTGMGAAAVFE 430
Cdd:PRK07851 389 TMCVGGGQGMAMVLE 403
|
|
| Thiolase_N |
pfam00108 |
Thiolase, N-terminal domain; Thiolase is reported to be structurally related to beta-ketoacyl ... |
48-301 |
1.39e-101 |
|
Thiolase, N-terminal domain; Thiolase is reported to be structurally related to beta-ketoacyl synthase (pfam00109), and also chalcone synthase.
Pssm-ID: 459676 [Multi-domain] Cd Length: 260 Bit Score: 303.07 E-value: 1.39e-101
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 48 VVVVHGRRTPIGRAGrGGFKDTTPDELLSAVLTAVLQDVKLKPECLGDISVGNVLEPGAGAVMARIAQFLSGIPETVPLS 127
Cdd:pfam00108 1 VVIVSAARTPFGSFG-GSLKDVSAVELGAEAIKAALERAGVDPEDVDEVIVGNVLQAGEGQNPARQAALKAGIPDSAPAV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 128 AVNRQCSSGLQAVANIAGGIRNGSYDIGMACGVESMSLSNRGNPGN-ISSRLLESDKARDCLIP-----------MGITS 195
Cdd:pfam00108 80 TINKVCGSGLKAVYLAAQSIASGDADVVLAGGVESMSHAPYALPTDaRSGLKHGDEKKHDLLIPdgltdafngyhMGLTA 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 196 ENVAERFGISRQKQDAFALASQQKAASAQSKGCFRAEIVPVTTTVLDDKGdrktiTVSQDEGVRPSTTMEGLAKLKPAFK 275
Cdd:pfam00108 160 ENVAKKYGISREEQDAFAVKSHQKAAAAPKAGKFKDEIVPVTVKGRKGKP-----TVDKDEGIRPPTTAEPLAKLKPAFD 234
|
250 260
....*....|....*....|....*.
gi 2074188883 276 DGGSTTAGNSSQVSDGAAAVLLARRS 301
Cdd:pfam00108 235 KEGTVTAGNASPINDGAAAVLLMSES 260
|
|
| PRK08242 |
PRK08242 |
acetyl-CoA C-acetyltransferase; |
55-430 |
7.79e-101 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 236197 [Multi-domain] Cd Length: 402 Bit Score: 306.42 E-value: 7.79e-101
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 55 RTPIGRAGRGG-FKDTTPDELLSAVLTAVLQDVKLKPECLGDISVGNVLEPG-AGAVMARIAQFLSGIPETVPLSAVNRQ 132
Cdd:PRK08242 11 RTPRGKGKKDGsLHEVKPVRLAAGLLEALRDRNGLDTAAVDDVVLGCVTPVGdQGADIARTAVLAAGLPETVPGVQINRF 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 133 CSSGLQAVANIAGGIRNGSYDIGMACGVESMSLSNRGNPG---------NISSRLlesdkardclIPMGITSENVAERFG 203
Cdd:PRK08242 91 CASGLEAVNLAAAKVRSGWDDLVIAGGVESMSRVPMGSDGgawamdpstNFPTYF----------VPQGISADLIATKYG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 204 ISRQKQDAFALASQQKAASAQSKGCFRAEIVPVTT----TVLDdkgdrktitvsQDEGVRPSTTMEGLAKLKPAFKDGGS 279
Cdd:PRK08242 161 FSREDVDAYAVESQQRAAAAWAEGYFAKSVVPVKDqnglTILD-----------HDEHMRPGTTMESLAKLKPSFAMMGE 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 280 T---------------------TAGNSSQVSDGAAAVLLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAYAIPAA 338
Cdd:PRK08242 230 MggfdavalqkypeverinhvhHAGNSSGIVDGAAAVLIGSEEAGKALGLKPRARIVATATIGSDPTIMLTGPVPATRKA 309
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 339 LQKAGLTVNDIDIFEINEAFASQALYCVEKLGIPAEKVNPLGGAIALGHPLGCTGARQVVTLLNELKRRGRRaYGVVSMC 418
Cdd:PRK08242 310 LAKAGLTVDDIDLFELNEAFASVVLRFMQALDIPHDKVNVNGGAIAMGHPLGATGAMILGTVLDELERRGKR-TALITLC 388
|
410
....*....|..
gi 2074188883 419 IGTGMGAAAVFE 430
Cdd:PRK08242 389 VGGGMGIATIIE 400
|
|
| PRK05656 |
PRK05656 |
acetyl-CoA C-acetyltransferase; |
47-432 |
1.22e-97 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 168156 Cd Length: 393 Bit Score: 297.96 E-value: 1.22e-97
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 47 DVVVVHGRRTPIGrAGRGGFKDTTPDELLSAVLTAVLQDVKLKPECLGDISVGNVLEPGAGAVMARIAQFLSGIPETVPL 126
Cdd:PRK05656 3 DVVIVAATRTAIG-SFQGSLANIPAVELGAAVIRRLLEQTGLDPAQVDEVILGQVLTAGAGQNPARQAAIKAGLPHSVPA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 127 SAVNRQCSSGLQAVANIAGGIRNGSYDIGMACGVESMSLSNRGNPGNISSRLLESDKARDCLIP-----------MGITS 195
Cdd:PRK05656 82 MTLNKVCGSGLKALHLAAQAIRCGDAEVIIAGGQENMSLAPYVLPGARTGLRMGHAQLVDSMITdglwdafndyhMGITA 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 196 ENVAERFGISRQKQDAFALASQQKAASAQSKGCFRAEIVPVTttVLDDKGDrkTITVSQDEGVRPSTTMEGLAKLKPAFK 275
Cdd:PRK05656 162 ENLVEKYGISREAQDAFAAASQQKAVAAIEAGRFDDEITPIL--IPQRKGE--PLAFATDEQPRAGTTAESLAKLKPAFK 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 276 DGGSTTAGNSSQVSDGAAAVLLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAYAIPAALQKAGLTVNDIDIFEIN 355
Cdd:PRK05656 238 KDGSVTAGNASSLNDGAAAVLLMSAAKAKALGLPVLAKIAAYANAGVDPAIMGIGPVSATRRCLDKAGWSLAELDLIEAN 317
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2074188883 356 EAFASQALYCVEKLGIPAEKVNPLGGAIALGHPLGCTGARQVVTLLNELKRRGRRAyGVVSMCIGTGMGAAAVFEYP 432
Cdd:PRK05656 318 EAFAAQSLAVGKELGWDAAKVNVNGGAIALGHPIGASGCRVLVTLLHEMIRRDAKK-GLATLCIGGGQGVALAIERD 393
|
|
| PRK08235 |
PRK08235 |
acetyl-CoA C-acetyltransferase; |
49-432 |
4.56e-97 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 181311 [Multi-domain] Cd Length: 393 Bit Score: 296.24 E-value: 4.56e-97
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 49 VVVHGRRTPIGRAGrGGFKDTTPDELLSAVLTAVLQDVKLKPECLGDISVGNVLEPGAGAVMARIAQFLSGIPETVPLSA 128
Cdd:PRK08235 5 VIVSAARTPFGKFG-GSLKDVKATELGGIAIKEALERANVSAEDVEEVIMGTVLQGGQGQIPSRQAARAAGIPWEVQTET 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 129 VNRQCSSGLQAVANIAGGIRNGSYDIGMACGVESMSLSNRGNPGNISSRLLESDKARDCLI-----------PMGITSEN 197
Cdd:PRK08235 84 VNKVCASGLRAVTLADQIIRAGDASVIVAGGMESMSNAPYILPGARWGYRMGDNEVIDLMVadgltcafsgvHMGVYGGE 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 198 VAERFGISRQKQDAFALASQQKAASAQSKGCFRAEIVPVTttVLDDKGDrkTITVSQDEGVRPSTTMEGLAKLKPAFKDG 277
Cdd:PRK08235 164 VAKELGISREAQDEWAYRSHQRAVSAHEEGRFEEEIVPVT--IPQRKGD--PIVVAKDEAPRKDTTIEKLAKLKPVFDKT 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 278 GSTTAGNSSQVSDGAAAVLLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAYAIPAALQKAGLTVNDIDIFEINEA 357
Cdd:PRK08235 240 GTITAGNAPGVNDGAAALVLMSEDRAKQEGRKPLATILAHTAIAVEAKDFPRTPGYAINALLEKTGKTVEDIDLFEINEA 319
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2074188883 358 FASQALYCVEKLGIPAEKVNPLGGAIALGHPLGCTGARQVVTLLNELKRRGrRAYGVVSMCIGTGMGAAAVFEYP 432
Cdd:PRK08235 320 FAAVALASTEIAGIDPEKVNVNGGAVALGHPIGASGARIIVTLIHELKRRG-GGIGIAAICSGGGQGDAVLIEVH 393
|
|
| PLN02644 |
PLN02644 |
acetyl-CoA C-acetyltransferase |
47-430 |
7.34e-96 |
|
acetyl-CoA C-acetyltransferase
Pssm-ID: 215347 [Multi-domain] Cd Length: 394 Bit Score: 293.15 E-value: 7.34e-96
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 47 DVVVVHGRRTPIGrAGRGGFKDTTPDELLSAVLTAVLQDVKLKPECLGDISVGNVLEPGAGAVMARIAQFLSGIPETVPL 126
Cdd:PLN02644 2 DVCIVGVARTPIG-GFLGSLSSLSATELGSIAIQAALERAGVDPALVQEVFFGNVLSANLGQAPARQAALGAGLPPSTIC 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 127 SAVNRQCSSGLQAVANIAGGIRNGSYDIGMACGVESMSLSNRGNPGNISSRLLESDKARDCLI-----------PMGITS 195
Cdd:PLN02644 81 TTVNKVCASGMKAVMLAAQSIQLGINDVVVAGGMESMSNAPKYLPEARKGSRLGHDTVVDGMLkdglwdvyndfGMGVCA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 196 ENVAERFGISRQKQDAFALASQQKAASAQSKGCFRAEIVPVTTTVlddKGDRKTITVSQDEGVRpSTTMEGLAKLKPAFK 275
Cdd:PLN02644 161 ELCADQYSISREEQDAYAIQSYERAIAAQEAGAFAWEIVPVEVPG---GRGRPSVIVDKDEGLG-KFDPAKLRKLRPSFK 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 276 -DGGSTTAGNSSQVSDGAAAVLLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAYAIPAALQKAGLTVNDIDIFEI 354
Cdd:PLN02644 237 eDGGSVTAGNASSISDGAAALVLVSGEKALELGLQVIAKIRGYADAAQAPELFTTAPALAIPKALKHAGLEASQVDYYEI 316
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2074188883 355 NEAFASQALYCVEKLGIPAEKVNPLGGAIALGHPLGCTGARQVVTLLNELKRRGRRaYGVVSMCIGTGMGAAAVFE 430
Cdd:PLN02644 317 NEAFSVVALANQKLLGLDPEKVNVHGGAVSLGHPIGCSGARILVTLLGVLRSKNGK-YGVAGICNGGGGASAIVVE 391
|
|
| PRK06633 |
PRK06633 |
acetyl-CoA C-acetyltransferase; |
48-430 |
1.72e-95 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 168632 [Multi-domain] Cd Length: 392 Bit Score: 292.32 E-value: 1.72e-95
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 48 VVVVHGRRTPIGRAGrgGFKDTTPDELLSAVLTA-VLQDVKLKPECLGDISVGNVLEPGAGAVMARIAQFLSGIPETVPL 126
Cdd:PRK06633 5 VYITHAKRTAFGSFM--GSLSTTPAPMLAAHLIKdILQNSKIDPALVNEVILGQVITGGSGQNPARQTLIHAGIPKEVPG 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 127 SAVNRQCSSGLQAVANIAGGIRNGSYDIGMACGVESMSLSNRGNPGNISSR--------LLESDKARDCL--IPMGITSE 196
Cdd:PRK06633 83 YTINKVCGSGLKSVALAANSIMTGDNEIVIAGGQENMSLGMHGSYIRAGAKfgdikmvdLMQYDGLTDVFsgVFMGITAE 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 197 NVAERFGISRQKQDAFALASQQKAASAQSKGCFRAEIVPVTTTVlddkgDRKTITVSQDEGVRPSTTMEGLAKLKPAFKD 276
Cdd:PRK06633 163 NISKQFNISRQEQDEFALSSHKKAAKAQLAGIFKDEILPIEVTI-----KKTTSLFDHDETVRPDTSLEILSKLRPAFDK 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 277 GGSTTAGNSSQVSDGAAAVLLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAYAIPAALQKAGLTVNDIDIFEINE 356
Cdd:PRK06633 238 NGVVTAGNASSINDGAACLMVVSEEALKKHNLTPLARIVSYASAGVDPSIMGTAPVPASQKALSKAGWSVNDLEVIEVNE 317
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2074188883 357 AFASQALYCVEKLGIPAEKVNPLGGAIALGHPLGCTGARQVVTLLNELkRRGRRAYGVVSMCIGTGMGAAAVFE 430
Cdd:PRK06633 318 AFAAQSIYVNREMKWDMEKVNINGGAIAIGHPIGASGGRVLITLIHGL-RRAKAKKGLVTLCIGGGMGMAMCVE 390
|
|
| PRK08131 |
PRK08131 |
3-oxoadipyl-CoA thiolase; |
47-430 |
3.04e-95 |
|
3-oxoadipyl-CoA thiolase;
Pssm-ID: 181242 [Multi-domain] Cd Length: 401 Bit Score: 292.07 E-value: 3.04e-95
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 47 DVVVVHGRRTPIGRAGrGGFKDTTPDELLSAVLTAVLQDVKLKPECLGDISVGNVLEPGAGAV-MARIAQFLSGIPETVP 125
Cdd:PRK08131 3 DAYIYDGLRSPFGRHA-GALASVRPDDLAATVIRRLLEKSGFPGDDIEDVILGCTNQAGEDSRnVARNALLLAGLPVTVP 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 126 LSAVNRQCSSGLQAVANIAGGIRNGSYDIGMACGVESMSLSN--RGNPGNISSRLLesdKARDCLI-------------- 189
Cdd:PRK08131 82 GQTVNRLCASGLAAVIDAARAITCGEGDLYLAGGVESMSRAPfvMGKAESAFSRDA---KVFDTTIgarfpnpkivaqyg 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 190 --PMGITSENVAERFGISRQKQDAFALASQQKAASAQSKGCFRAEIVPVTTTVLDDKGDRKtitVSQDEGVRPSTTMEGL 267
Cdd:PRK08131 159 ndSMPETGDNVAAEFGISREDADRFAAQSQAKYQAAKEEGFFADEITPIEVPQGRKLPPKL---VAEDEHPRPSSTVEAL 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 268 AKLKPAFkDGGSTTAGNSSQVSDGAAAVLLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAYAIPAALQKAGLTVN 347
Cdd:PRK08131 236 TKLKPLF-EGGVVTAGNASGINDGAAALLIGSRAAGEKYGLKPMARILSSAAAGVEPRIMGIGPVEAIKKALARAGLTLD 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 348 DIDIFEINEAFASQALYCVEKLGIPAE--KVNPLGGAIALGHPLGCTGARQVVTLLNELKRRGRRaYGVVSMCIGTGMGA 425
Cdd:PRK08131 315 DMDIIEINEAFASQVLGCLKGLGVDFDdpRVNPNGGAIAVGHPLGASGARLALTAARELQRRGKR-YAVVSLCIGVGQGL 393
|
....*
gi 2074188883 426 AAVFE 430
Cdd:PRK08131 394 AMVIE 398
|
|
| PRK07850 |
PRK07850 |
steroid 3-ketoacyl-CoA thiolase; |
49-430 |
8.41e-93 |
|
steroid 3-ketoacyl-CoA thiolase;
Pssm-ID: 181145 [Multi-domain] Cd Length: 387 Bit Score: 285.08 E-value: 8.41e-93
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 49 VVVHGRRTPIGRAGrGGFKDTTPDELLSAVLTAVLQDVKLKPECLGDISVGNVLEPGA-GAVMARIAQFLSGIPETVPLS 127
Cdd:PRK07850 5 VIVEAVRTPIGKRN-GWLSGLHAAELLGAVQRAVLDRAGIDPGDVEQVIGGCVTQAGEqSNNITRTAWLHAGLPYHVGAT 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 128 AVNRQCSSGLQAVANIAGGIRNGSYDIGMACGVESMSL----SNRG-NPGNIssrllesdKARDCLIPMG---ITSENVA 199
Cdd:PRK07850 84 TIDCQCGSAQQANHLVAGLIAAGAIDVGIACGVEAMSRvplgANAGpGRGLP--------RPDSWDIDMPnqfEAAERIA 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 200 ERFGISRQKQDAFALASQQKAASAQSKGCFRAEIVPVTTTVLDDKGDR--KTITVSQDEGVRpSTTMEGLAKLKPAFkDG 277
Cdd:PRK07850 156 KRRGITREDVDAFGLRSQRRAAQAWAEGRFDREISPVQAPVLDEEGQPtgETRLVTRDQGLR-DTTMEGLAGLKPVL-EG 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 278 GSTTAGNSSQVSDGAAAVLLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAYAIPAALQKAGLTVNDIDIFEINEA 357
Cdd:PRK07850 234 GIHTAGTSSQISDGAAAVLWMDEDRARALGLRPRARIVAQALVGAEPYYHLDGPVQATAKVLEKAGMKIGDIDLVEINEA 313
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2074188883 358 FASQALYCVEKLGIPAEKVNPLGGAIALGHPLGCTGARQVVTLLNELKRRGRRaYGVVSMCIGTGMGAAAVFE 430
Cdd:PRK07850 314 FASVVLSWAQVHEPDMDKVNVNGGAIALGHPVGSTGARLITTALHELERTDKS-TALITMCAGGALSTGTIIE 385
|
|
| PRK08170 |
PRK08170 |
acetyl-CoA C-acetyltransferase; |
47-430 |
1.30e-85 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 181265 [Multi-domain] Cd Length: 426 Bit Score: 268.04 E-value: 1.30e-85
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 47 DVVVVHGRRTPIGRAgRGGFKDTTPDELLSAVLTAVLQDVKLKPECLGDISVGNVLePGAGAV-MARIAQFLSGIPETVP 125
Cdd:PRK08170 4 PVYIVDGARTPFLKA-RGGPGPFSASDLAVAAGRALLNRQPFAPDDLDEVILGCAM-PSPDEAnIARVVALRLGCGEKVP 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 126 LSAVNRQCSSGLQAVANIAGGIRNGSYDIGMACGVESMS-----LSNRG--------NPGNISSRLLESDKAR-DCLIP- 190
Cdd:PRK08170 82 AWTVQRNCASGMQALDSAAANIALGRADLVLAGGVEAMShapllFSEKMvrwlagwyAAKSIGQKLAALGKLRpSYLAPv 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 191 ---------------MGITSENVAERFGISRQKQDAFALASQQKAASAQSKGcFRAEIVPVTttvlddkgDRKTITVSQD 255
Cdd:PRK08170 162 igllrgltdpvvglnMGQTAEVLAHRFGITREQMDAYAARSHQRLAAAQAEG-RLKEVVPLF--------DRDGKFYDHD 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 256 EGVRPSTTMEGLAKLKPAF-KDGGSTTAGNSSQVSDGAAAVLLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAYA 334
Cdd:PRK08170 233 DGVRPDSSMEKLAKLKPFFdRPYGRVTAGNSSQITDGACWLLLASEEAVKKYGLPPLGRIVDSQWAALDPSQMGLGPVHA 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 335 IPAALQKAGLTVNDIDIFEINEAFASQAL----------YCVEKLGIPA-------EKVNPLGGAIALGHPLGCTGARQV 397
Cdd:PRK08170 313 ATPLLQRHGLTLEDLDLWEINEAFAAQVLaclaawadeeYCREQLGLDGalgeldrERLNVDGGAIALGHPVGASGARIV 392
|
410 420 430
....*....|....*....|....*....|...
gi 2074188883 398 VTLLNELKRRGRRaYGVVSMCIGTGMGAAAVFE 430
Cdd:PRK08170 393 LHLLHALKRRGTK-RGIAAICIGGGQGGAMLLE 424
|
|
| fadI |
PRK08963 |
3-ketoacyl-CoA thiolase; Reviewed |
48-430 |
3.32e-85 |
|
3-ketoacyl-CoA thiolase; Reviewed
Pssm-ID: 181597 [Multi-domain] Cd Length: 428 Bit Score: 266.85 E-value: 3.32e-85
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 48 VVVVHGRRTPIGRAGRGgFKDTTPDELLSAVLTAVLQDVKLKPECLGDISVGNVLEPGAGAVMARIAQFLSGIPETVPLS 127
Cdd:PRK08963 7 IAIVSGLRTPFAKQATA-FHGIPAVDLGKMVVGELLARSEIDPELIEQLVFGQVVQMPEAPNIAREIVLGTGMNVHTDAY 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 128 AVNRQCSSGLQAVANIAGGIRNGSYDIGMACGVESMSLSNRGNPGNISSRLLESDKARDC--------------LIP--- 190
Cdd:PRK08963 86 SVSRACATSFQAVANVAESIMAGTIDIGIAGGADSSSVLPIGVSKKLARALVDLNKARTLgqrlklfsrlrlrdLLPvpp 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 191 ----------MGITSENVAERFGISRQKQDAFALASQQKAASAQSKGCFRAEivpVTTTVLDDKGDrktiTVSQDEGVRP 260
Cdd:PRK08963 166 avaeystglrMGDTAEQMAKTYGISREEQDALAHRSHQLAAQAWAEGKLDDE---VMTAHVPPYKQ----PLEEDNNIRG 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 261 STTMEGLAKLKPAF-KDGGSTTAGNSSQVSDGAAAVLLARRSKAEELGLPILGVLRSYAVVGVPP-DIMGIGPAYAIPAA 338
Cdd:PRK08963 239 DSTLEDYAKLRPAFdRKHGTVTAANSTPLTDGAAAVLLMSESRAKALGLTPLGYLRSYAFAAIDVwQDMLLGPAYATPLA 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 339 LQKAGLTVNDIDIFEINEAFASQAL----------YCVEKLG-------IPAEKVNPLGGAIALGHPLGCTGARQVVTLL 401
Cdd:PRK08963 319 LERAGLTLADLTLIDMHEAFAAQTLanlqmfaserFAREKLGrsqaigeVDMSKFNVLGGSIAYGHPFAATGARMITQTL 398
|
410 420
....*....|....*....|....*....
gi 2074188883 402 NELKRRGrRAYGVVSMCIGTGMGAAAVFE 430
Cdd:PRK08963 399 HELRRRG-GGLGLTTACAAGGLGAAMVLE 426
|
|
| PRK07801 |
PRK07801 |
acetyl-CoA C-acetyltransferase; |
46-430 |
6.86e-81 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 181123 [Multi-domain] Cd Length: 382 Bit Score: 254.25 E-value: 6.86e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 46 SDVVVVHGRRTPIGRAGrGGFKDTTPDELLSAVLTAVLQDVKLKPECLGDISVGNV--LEPGAGAVmARIAQFLSGIPET 123
Cdd:PRK07801 2 AEAYIVDAVRTPVGKRK-GGLAGVHPADLGAHVLKGLVDRTGIDPAAVDDVIFGCVdtIGPQAGNI-ARTSWLAAGLPEE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 124 VPLSAVNRQCSSGLQAVANIAGGIRNGSYDIGMACGVESMSL----SNR--GNPGNISSRLLESDKAR----DCLIPMGI 193
Cdd:PRK07801 80 VPGVTVDRQCGSSQQAIHFAAQAVMSGTQDLVVAGGVQNMSQipisSAMtaGEQLGFTSPFAESKGWLhrygDQEVSQFR 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 194 TSENVAERFGISRQKQDAFALASQQKAASAQSKGCFRAEIVPVtttvlddkGDrktitVSQDEGVRpSTTMEGLAKLKPa 273
Cdd:PRK07801 160 GAELIAEKWGISREEMERFALESHRRAFAAIRAGRFDNEIVPV--------GG-----VTVDEGPR-ETSLEKMAGLKP- 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 274 FKDGGSTTAGNSSQVSDGAAAVLLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAYAIPAALQKAGLTVNDIDIFE 353
Cdd:PRK07801 225 LVEGGRLTAAVASQISDGASAVLLASERAVKRHGLTPRARIHHLSVRGDDPVFMLTAPIPATRYALEKTGLSIDDIDVVE 304
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2074188883 354 INEAFASQALYCVEKLGIPAEKVNPLGGAIALGHPLGCTGARQVVTLLNELKRRGRRaYGVVSMCIGTGMGAAAVFE 430
Cdd:PRK07801 305 INEAFAPVVLAWLKETGADPAKVNPNGGAIALGHPLGATGAKLMTTLLHELERTGGR-YGLQTMCEGGGTANVTIIE 380
|
|
| PRK06690 |
PRK06690 |
acetyl-CoA C-acyltransferase; |
49-430 |
2.52e-76 |
|
acetyl-CoA C-acyltransferase;
Pssm-ID: 180659 [Multi-domain] Cd Length: 361 Bit Score: 241.98 E-value: 2.52e-76
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 49 VVVHGRRTPIGRAGrGGFKDTTPDELLSAVLTAVLQDVklkPECLGDISVGNVLEPGAGavMARIAQFLSGIPETVPLSA 128
Cdd:PRK06690 4 VIVEAKRTPIGKKN-GMLKDYEVQQLAAPLLTFLSKGM---EREIDDVILGNVVGPGGN--VARLSALEAGLGLHIPGVT 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 129 VNRQCSSGLQAVANIAGGIRNGSYDIGMACGVESMSLSNRGNPGNISSRLLeSDKArdclipMGITSENVAERFGISRQK 208
Cdd:PRK06690 78 IDRQCGAGLEAIRTACHFIQGGAGKCYIAGGVESTSTSPFQNRARFSPETI-GDPD------MGVAAEYVAERYNITREM 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 209 QDAFALASQQKAASAQSKGCFRAEIVPVTTTVlddkgdrktitvsqDEGVRPSTTMEGL-AKLKPAFKDGGSTTAGNSSQ 287
Cdd:PRK06690 151 QDEYACLSYKRTLQALEKGYIHEEILSFNGLL--------------DESIKKEMNYERIiKRTKPAFLHNGTVTAGNSCG 216
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 288 VSDGAAAVLLARRSKAEELGL-PILGVLRSyAVVGVPPDIMGIGPAYAIPAALQKAGLTVNDIDIFEINEAFASQALYCV 366
Cdd:PRK06690 217 VNDGACAVLVMEEGQARKLGYkPVLRFVRS-AVVGVDPNLPGTGPIFAVNKLLNEMNMKVEDIDYFEINEAFASKVVACA 295
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2074188883 367 EKLGIPAEKVNPLGGAIALGHPLGCTGARQVVTLLNELKRRGRRaYGVVSMCIGTGMGAAAVFE 430
Cdd:PRK06690 296 KELQIPYEKLNVNGGAIALGHPYGASGAMLVTRLFYQAKREDMK-YGIATLGIGGGIGLALLFE 358
|
|
| PRK06504 |
PRK06504 |
acetyl-CoA C-acetyltransferase; |
50-430 |
7.83e-76 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 180595 [Multi-domain] Cd Length: 390 Bit Score: 241.56 E-value: 7.83e-76
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 50 VVHGRRTPIGRAGrGGFKDTTPDELLSAVLTAVLQDVKLKPECLGDISVGNVLEPGAGAV-MARIAQFLSGIPETVPLSA 128
Cdd:PRK06504 6 IVAAARTAGGRKG-GRLAGWHPADLAAQVLDALVDRSGADPALIEDVIMGCVSQVGEQATnVARNAVLASKLPESVPGTS 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 129 VNRQCSSGLQAVANIAGGIRNGSYDIGMACGVESMSLSNRGNP---------GNISSRLLEsDKARDCLIPMGITSENVA 199
Cdd:PRK06504 85 IDRQCGSSQQALHFAAQAVMSGTMDIVIAAGVESMTRVPMGSPstlpaknglGHYKSPGME-ERYPGIQFSQFTGAEMMA 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 200 ERFGISRQKQDAFALASQQKAASAQSKGCFRAEIVPVTTTVLDDKGDRKTItvsqDEGVRPSTTMEGLAKLKPaFKDGGS 279
Cdd:PRK06504 164 KKYGLSKDQLDEFALQSHQRAIAATQAGKFKAEIVPLEITRADGSGEMHTV----DEGIRFDATLEGIAGVKL-IAEGGR 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 280 TTAGNSSQVSDGAAAVLLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAYAIPAALQKAGLTVNDIDIFEINEAFA 359
Cdd:PRK06504 239 LTAATASQICDGASGVMVVNERGLKALGVKPLARIHHMTVIGGDPVIMLEAPLPATERALKKAGMKIDDIDLYEVNEAFA 318
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2074188883 360 SQALYCVEKLGIPAEKVNPLGGAIALGHPLGCTGARQVVTLLNELKRRGRRaYGVVSMCIGTGMGAAAVFE 430
Cdd:PRK06504 319 SVPLAWLKATGADPERLNVNGGAIALGHPLGASGTKLMTTLVHALKQRGKR-YGLQTMCEGGGMANVTIVE 388
|
|
| PRK06025 |
PRK06025 |
acetyl-CoA C-acetyltransferase; |
46-430 |
9.58e-71 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 235675 [Multi-domain] Cd Length: 417 Bit Score: 229.28 E-value: 9.58e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 46 SDVVVVHGRRTP--IGRAGRGGFKDTTPDELLSAVLTAVLQDVKLKPECLGDISVGNVLEPGA-GAVMARIAQFLSGIPE 122
Cdd:PRK06025 2 AEAYIIDAVRTPrgIGKVGKGALAHLHPQHLAATVLKALAERNGLNTADVDDIIWSTSSQRGKqGGDLGRMAALDAGYDI 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 123 TVPLSAVNRQCSSGLQAVANIAGGIRNGSYDIGMACGVESMSL----SNRGNPGNISSRLLESDKAR-DCLIPM---GIT 194
Cdd:PRK06025 82 KASGVTLDRFCGGGITSVNLAAAQIMSGMEDLVIAGGTEMMSYtaamAAEDMAAGKPPLGMGSGNLRlRALHPQshqGVC 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 195 SENVAERFGISRQKQDAFALASQQKAASAQSKGCFRAEIVPVtttvLDDKGdrkTITVSQDEGVRPSTTMEGLAKLKPAF 274
Cdd:PRK06025 162 GDAIATMEGITREALDALGLESQRRAARAIKEGRFDKSLVPV----YRDDG---SVALDHEEFPRPQTTAEGLAALKPAF 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 275 K--------DGGSTT------------------AGNSSQVSDGAAAVLLARRSKAEELGLPILGVLRSYAVVGVPPDIMG 328
Cdd:PRK06025 235 TaiadypldDKGTTYrglinqkypdleikhvhhAGNSSGVVDGAAALLLASKAYAEKHGLKPRARIVAMANMGDDPTLML 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 329 IGPAYAIPAALQKAGLTVNDIDIFEINEAFASQALYCVEKLGIPAEKVNPLGGAIALGHPLGCTGARQVVTLLNELKRRG 408
Cdd:PRK06025 315 NAPVPAAKKVLAKAGLTKDDIDLWEINEAFAVVAEKFIRDLDLDRDKVNVNGGAIALGHPIGATGSILIGTVLDELERRG 394
|
410 420
....*....|....*....|..
gi 2074188883 409 RRaYGVVSMCIGTGMGAAAVFE 430
Cdd:PRK06025 395 LK-RGLVTMCAAGGMAPAIIIE 415
|
|
| PRK06366 |
PRK06366 |
acetyl-CoA C-acetyltransferase; |
47-430 |
4.30e-70 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 102340 [Multi-domain] Cd Length: 388 Bit Score: 226.82 E-value: 4.30e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 47 DVVVVHGRRTPIGRAGRGGFKDTTPdELLSAVLTAVLQDVKLKPECLGDISVGNVLEPGAGAVMARIAQFLSGIPETVPL 126
Cdd:PRK06366 3 DVYIVSAKRTAIGKFGRSFSKIKAP-QLGGAAIKAVIDDAKLDPALVQEVIMGNVIQAGVGQNPAGQAAYHAGLPFGVTK 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 127 SAVNRQCSSGLQAVANIAGGIRNGSYDIGMACGVESMSLSN-------RGNPGNISSRLLESDKAR--DCLIP------M 191
Cdd:PRK06366 82 YTVNVVCASGMLAVESAAREIMLGERDLVIAGGMENMSNAPfllpsdlRWGPKHLLHKNYKIDDAMlvDGLIDafyfehM 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 192 GITSENVAERFGISRQKQDAFALASQQKAASAQSKGCFRAEIVPVTTtvlddkgdrktitVSQDEGVRpSTTMEGLAKLK 271
Cdd:PRK06366 162 GVSAERTARKYGITREMADEYSVQSYERAIRATESGEFRNEIVPFND-------------LDRDEGIR-KTTMEDLAKLP 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 272 PAFKDGGSTTAGNSSQVSDGAAAVLLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAYAIPAALQKAGLTVNDIDI 351
Cdd:PRK06366 228 PAFDKNGILTAGNSAQLSDGGSALVMASEKAINEYGLKPIARITGYESASLDPLDFVEAPIPATRKLLEKQNKSIDYYDL 307
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2074188883 352 FEINEAFASQALYCVEKLGIPAEKVNPLGGAIALGHPLGCTGARQVVTLLNELKRRGRRAyGVVSMCIGTGMGAAAVFE 430
Cdd:PRK06366 308 VEHNEAFSIASIIVRDQLKIDNERFNVNGGAVAIGHPIGNSGSRIIVTLINALKTRHMKT-GLATLCHGGGGAHTLTLE 385
|
|
| PRK06954 |
PRK06954 |
acetyl-CoA C-acetyltransferase; |
48-430 |
5.32e-70 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 180775 [Multi-domain] Cd Length: 397 Bit Score: 226.70 E-value: 5.32e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 48 VVVVHGRRTPIGrAGRGGFKDTTPDELLSAVLTAVLQDVKLKPECLGDISVGNVLEPGAGAVMARIAQFLSGIPETVPLS 127
Cdd:PRK06954 9 IVIASAARTPMA-AFQGEFASLTAPQLGAAAIAAAVERAGLKPEQIDEVVMGCVLPAGQGQAPARQAALGAGLPLSVGCT 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 128 AVNRQCSSGLQAVANIAGGIRNGSYDIGMACGVESMSLSN----------RGNPGNISSRL----LES--DKARdcliPM 191
Cdd:PRK06954 88 TVNKMCGSGMRAAMFAHDMLVAGSVDVIVAGGMESMTNAPyllpkarggmRMGHGQVLDHMfldgLEDayDKGR----LM 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 192 GITSENVAERFGISRQKQDAFALASQQKAASAQSKGCFRAEIVPVTttVLDDKGDrktITVSQDEGVRpSTTMEGLAKLK 271
Cdd:PRK06954 164 GTFAEECAGEYGFTREAQDAFAIESLARAKRANEDGSFAWEIAPVT--VAGKKGD---TVIDRDEQPF-KANPEKIPTLK 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 272 PAFKDGGSTTAGNSSQVSDGAAAVLLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAYAIPAALQKAGLTVNDIDI 351
Cdd:PRK06954 238 PAFSKTGTVTAANSSSISDGAAALVMMRASTAKRLGLAPLARVVGHSTFAQAPSKFTTAPVGAIRKLFEKNGWRAAEVDL 317
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2074188883 352 FEINEAFASQALYCVEKLGIPAEKVNPLGGAIALGHPLGCTGARQVVTLLNELKRRGRRAyGVVSMCIGTGMGAAAVFE 430
Cdd:PRK06954 318 FEINEAFAVVTMAAMKEHGLPHEKVNVNGGACALGHPIGASGARILVTLIGALRARGGKR-GVASLCIGGGEATAMGIE 395
|
|
| PRK09268 |
PRK09268 |
acetyl-CoA C-acetyltransferase; |
41-430 |
2.39e-67 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 236440 [Multi-domain] Cd Length: 427 Bit Score: 220.54 E-value: 2.39e-67
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 41 PQASASDVVVVHGRRTPIGRAGrGGFKDTTPDELLSAVLTAVLQDVKLKPECLGDISVGNVLEPGAGAVMARIAQFLSGI 120
Cdd:PRK09268 2 TMPTVRRVAILGGNRIPFARSN-GAYADASNQDMLTAALDGLVDRFGLQGERLGEVVAGAVLKHSRDFNLTRECVLGSAL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 121 PETVPLSAVNRQCSSGLQAVANIAGGIRNGSYDIGMACGVESMSLSNRGNPGNISSRLLESDKARDC------------- 187
Cdd:PRK09268 81 SPYTPAYDLQQACGTGLEAAILVANKIALGQIDSGIAGGVDTTSDAPIAVNEGLRKILLELNRAKTTgdrlkalgklrpk 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 188 ----LIP----------MGITSENVAERFGISRQKQDAFALASQQKAASAQSKGCFRAEIVPVtttvlddKGdrktitVS 253
Cdd:PRK09268 161 hlapEIPrngeprtglsMGEHAAITAKEWGISREAQDELAAASHQNLAAAYDRGFFDDLITPF-------LG------LT 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 254 QDEGVRPSTTMEGLAKLKPAF--KDGGSTTAGNSSQVSDGAAAVLLARRSKAEELGLPILGVLRSYAVVGVP----PDIM 327
Cdd:PRK09268 228 RDNNLRPDSSLEKLAKLKPVFgkGGRATMTAGNSTPLTDGASVVLLASEEWAAEHGLPVLAYLVDAETAAVDfvhgKEGL 307
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 328 GIGPAYAIPAALQKAGLTVNDIDIFEINEAFASQAL----------YCVEKLGIPA-------EKVNPLGGAIALGHPLG 390
Cdd:PRK09268 308 LMAPAYAVPRLLARNGLTLQDFDFYEIHEAFASQVLatlkawedeeYCRERLGLDAplgsidrSKLNVNGSSLAAGHPFA 387
|
410 420 430 440
....*....|....*....|....*....|....*....|
gi 2074188883 391 CTGARQVVTLLNELKRRGrRAYGVVSMCIGTGMGAAAVFE 430
Cdd:PRK09268 388 ATGGRIVATLAKLLAEKG-SGRGLISICAAGGQGVTAILE 426
|
|
| Thiolase_C |
pfam02803 |
Thiolase, C-terminal domain; Thiolase is reported to be structurally related to beta-ketoacyl ... |
308-431 |
1.45e-66 |
|
Thiolase, C-terminal domain; Thiolase is reported to be structurally related to beta-ketoacyl synthase (pfam00109), and also chalcone synthase.
Pssm-ID: 397094 [Multi-domain] Cd Length: 123 Bit Score: 208.27 E-value: 1.45e-66
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 308 LPILGVLRSYAVVGVPPDIMGIGPAYAIPAALQKAGLTVNDIDIFEINEAFASQALYCVEKLGIPAEKVNPLGGAIALGH 387
Cdd:pfam02803 1 LKPLARIRSYATAGVDPAIMGIGPAYAIPKALKKAGLTVNDIDLFEINEAFAAQALAVAKDLGIDPEKVNVNGGAIALGH 80
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 2074188883 388 PLGCTGARQVVTLLNELKRRGRRaYGVVSMCIGTGMGAAAVFEY 431
Cdd:pfam02803 81 PLGASGARILVTLLHELKRRGGK-YGLASLCIGGGQGVAMIIER 123
|
|
| nondecarbox_cond_enzymes |
cd00826 |
nondecarboxylating condensing enzymes; In general, thiolases catalyze the reversible thiolytic ... |
55-431 |
6.49e-56 |
|
nondecarboxylating condensing enzymes; In general, thiolases catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. There are 2 functional different classes: thiolase-I (3-ketoacyl-CoA thiolase) and thiolase-II (acetoacetyl-CoA thiolase). Thiolase-I can cleave longer fatty acid molecules and plays an important role in the beta-oxidative degradation of fatty acids. Thiolase-II has a high substrate specificity. Although it can cleave acetoacyl-CoA, its main function is the synthesis of acetoacyl-CoA from two molecules of acetyl-CoA, which gives it importance in several biosynthetic pathways.
Pssm-ID: 238422 [Multi-domain] Cd Length: 393 Bit Score: 190.01 E-value: 6.49e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 55 RTPIGRAG--RGGFKDTTPDELLSAVLTAVLQDVKLKPECLGDISVGNVLEPGAGAVMARIAQFLSGIPETVPLSAVNRQ 132
Cdd:cd00826 5 MTAFGKFGgeNGADANDLAHEAGAKAIAAALEPAGVAAGAVEEACLGQVLGAGEGQNCAQQAAMHAGGLQEAPAIGMNNL 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 133 CSSGLQAVANIAGGIRNGSYDIGMACGVESMSLSNRGNPgnissrlleSDKARDCLIpmgitsenvaERFGiSRQKQDAF 212
Cdd:cd00826 85 CGSGLRALALAMQLIAGGDANCILAGGFEKMETSAENNA---------KEKHIDVLI----------NKYG-MRACPDAF 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 213 ALASQQKAASAQSKGCFRAEIVPVTTtvlddKGDRKTITVSQDEGVR--PSTTMEGLAKLKPAFKDGGSTTAGNSSQVSD 290
Cdd:cd00826 145 ALAGQAGAEAAEKDGRFKDEFAKFGV-----KGRKGDIHSDADEYIQfgDEASLDEIAKLRPAFDKEDFLTAGNACGLND 219
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 291 GAAAVLLARRSKAEELGLPI-------LGVLRSYAVVGVPPD----IMGIGPAYAIPAALQKAGLTVNDIDIFEINEAFA 359
Cdd:cd00826 220 GAAAAILMSEAEAQKHGLQSkareiqaLEMITDMASTFEDKKvikmVGGDGPIEAARKALEKAGLGIGDLDLIEAHDAFA 299
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 360 SQALYCVEKLGIPAEK------------------VNPLGGAIALGHPLGCTGARQVVTLLNELKRRGRRAY----GVVSM 417
Cdd:cd00826 300 ANACATNEALGLCPEGqggalvdrgdntyggksiINPNGGAIAIGHPIGASGAAICAELCFELKGEAGKRQgagaGLALL 379
|
410
....*....|....
gi 2074188883 418 CIGTGMGAAAVFEY 431
Cdd:cd00826 380 CIGGGGGAAMCIES 393
|
|
| SCP-x_thiolase |
cd00829 |
Thiolase domain associated with sterol carrier protein (SCP)-x isoform and related proteins; ... |
56-428 |
1.42e-21 |
|
Thiolase domain associated with sterol carrier protein (SCP)-x isoform and related proteins; SCP-2 has multiple roles in intracellular lipid circulation and metabolism. The N-terminal presequence in the SCP-x isoform represents a peroxisomal 3-ketacyl-Coa thiolase specific for branched-chain acyl CoAs, which is proteolytically cleaved from the sterol carrier protein.
Pssm-ID: 238425 [Multi-domain] Cd Length: 375 Bit Score: 95.41 E-value: 1.42e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 56 TPIGRAGrggfkDTTPDELLSAVLTAVLQDVKLKPECLGDISVGNVL-EPGAGAVMARIAQFLSGIPetVPLSAVNRQCS 134
Cdd:cd00829 6 TPFGRRS-----DRSPLELAAEAARAALDDAGLEPADIDAVVVGNAAgGRFQSFPGALIAEYLGLLG--KPATRVEAAGA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 135 SGLQAVANIAGGIRNGSYDIGMACGVESMSLSNRGNP--GNISSRLLESDKARDCLIPMGITSeNVA----ERFGISRqk 208
Cdd:cd00829 79 SGSAAVRAAAAAIASGLADVVLVVGAEKMSDVPTGDEagGRASDLEWEGPEPPGGLTPPALYA-LAArrymHRYGTTR-- 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 209 qDAFAL--ASQQKAASAQSKGCFRAEIvpvtttvlddkgdrktiTVSQDEGVRPSTTmeglaklkPafkdggsTTAGNSS 286
Cdd:cd00829 156 -EDLAKvaVKNHRNAARNPYAQFRKPI-----------------TVEDVLNSRMIAD--------P-------LRLLDCC 202
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 287 QVSDGAAAVLLARRSKAEELGLP---ILGV---LRSYAVVGVPPDIMGIGPAYAIPAALQKAGLTVNDIDIFEINEAFAS 360
Cdd:cd00829 203 PVSDGAAAVVLASEERARELTDRpvwILGVgaaSDTPSLSERDDFLSLDAARLAARRAYKMAGITPDDIDVAELYDCFTI 282
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 361 QALYCVEKLGIpAEK-------------------VNPLGGAIALGHPLGCTGARQVVTLLNELKRRGrRAYGV----VSM 417
Cdd:cd00829 283 AELLALEDLGF-CEKgeggklvregdtaiggdlpVNTSGGLLSKGHPLGATGLAQAVEAVRQLRGEA-GARQVpgarVGL 360
|
410
....*....|.
gi 2074188883 418 CIGTGMGAAAV 428
Cdd:cd00829 361 AHNIGGTGSAA 371
|
|
| cond_enzymes |
cd00327 |
Condensing enzymes; Family of enzymes that catalyze a (decarboxylating or non-decarboxylating) ... |
282-428 |
2.41e-16 |
|
Condensing enzymes; Family of enzymes that catalyze a (decarboxylating or non-decarboxylating) Claisen-like condensation reaction. Members are share strong structural similarity, and are involved in the synthesis and degradation of fatty acids, and the production of polyketides, a diverse group of natural products.
Pssm-ID: 238201 [Multi-domain] Cd Length: 254 Bit Score: 78.25 E-value: 2.41e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 282 AGNSSQVSDGAAAVLLARRSKAEELGLPILGVLRSYAVVGVPPD----IMGIGPAYAIPAALQKAGLTVNDIDIFEINEA 357
Cdd:cd00327 94 GSEEFVFGDGAAAAVVESEEHALRRGAHPQAEIVSTAATFDGASmvpaVSGEGLARAARKALEGAGLTPSDIDYVEAHGT 173
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 358 FASQALYCVEKLGIPAEKVNPL---GGAIALGHPLGCTGARQVVTLLNELKRRGRRAY------GVVSMCIGTGMGAAAV 428
Cdd:cd00327 174 GTPIGDAVELALGLDPDGVRSPavsATLIMTGHPLGAAGLAILDELLLMLEHEFIPPTpreprtVLLLGFGLGGTNAAVV 253
|
|
| PRK06064 |
PRK06064 |
thiolase domain-containing protein; |
285-427 |
1.42e-14 |
|
thiolase domain-containing protein;
Pssm-ID: 235688 [Multi-domain] Cd Length: 389 Bit Score: 74.93 E-value: 1.42e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 285 SSQVSDGAAAVLLARRSKAEELGLPILGVLRS-----YAVVGVPPDIMGIGPA-YAIPAALQKAGLTVNDIDIFEINEAF 358
Cdd:PRK06064 208 CSPITDGAAAVILASEEKAKEYTDTPVWIKASgqasdTIALHDRKDFTTLDAAvVAAEKAYKMAGIEPKDIDVAEVHDCF 287
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 359 ASQALYCVEKLGIpAEK-------------------VNPLGGAIALGHPLGCTGARQVVTLLNELKRRGRRAYGVVsmcI 419
Cdd:PRK06064 288 TIAEILAYEDLGF-AKKgeggklaregqtyiggdipVNPSGGLKAKGHPVGATGVSQAVEIVWQLRGEAEKGRQQV---I 363
|
....*...
gi 2074188883 420 GTGMGAAA 427
Cdd:PRK06064 364 GAGYGLTH 371
|
|
| PRK06289 |
PRK06289 |
acetyl-CoA acetyltransferase; Provisional |
73-395 |
8.56e-14 |
|
acetyl-CoA acetyltransferase; Provisional
Pssm-ID: 235771 [Multi-domain] Cd Length: 403 Bit Score: 72.41 E-value: 8.56e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 73 ELLSAVLTAVLQDVKLKPECLGDISVGNVlepgAGAVMARIAQfLSGIPETV-------PLSAVNRQCSSGLQAVANIAG 145
Cdd:PRK06289 28 DLTREVVDGTLAAAGVDADDIEVVHVGNF----FGELFAGQGH-LGAMPATVhpalwgvPASRHEAACASGSVATLAAMA 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 146 GIRNGSYDIGMACGVESMslsnRGNPGNISSRLLES-----DKARDCLIP----MGITSENVAERFGISRQKQDAFA--- 213
Cdd:PRK06289 103 DLRAGRYDVALVVGVELM----KTVPGDVAAEHLGAaawtgHEGQDARFPwpsmFARVADEYDRRYGLDEEHLRAIAein 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 214 LASQQKAASAQSKGCFraeiVPVTTTVLDDKgdrktitvsqdegvrpsttmeglakLKPAFkdGGSTTAGNSSQVSDGAA 293
Cdd:PRK06289 179 FANARRNPNAQTRGWA----FPDEATNDDDA-------------------------TNPVV--EGRLRRQDCSQVTDGGA 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 294 AVLLARRSKAEELG----LP-ILGVLRSYAVVGVPPDI-MGIGPAYAIPA-------ALQKAGLTVNDIDIFEINEAFAS 360
Cdd:PRK06289 228 GVVLASDAYLRDYAdarpIPrIKGWGHRTAPLGLEQKLdRSAGDPYVLPHvrqavldAYRRAGVGLDDLDGFEVHDCFTP 307
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|...
gi 2074188883 361 QALYCVEKLGI--PAEK----------------VNPLGGAIALGHPLGCTGAR 395
Cdd:PRK06289 308 SEYLAIDHIGLtgPGESwkaiengeiaiggrlpINPSGGLIGGGHPVGASGVR 360
|
|
| PRK12578 |
PRK12578 |
thiolase domain-containing protein; |
58-405 |
4.24e-11 |
|
thiolase domain-containing protein;
Pssm-ID: 183606 [Multi-domain] Cd Length: 385 Bit Score: 64.10 E-value: 4.24e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 58 IGRAGRGGFKDTTPDELLSAVLTAVLQDVKLKPECLGDISVGNVLEPGAGAVMARIAQFLSGIPETVPLSaVNRQCSSGL 137
Cdd:PRK12578 8 VGNSKFGRRDDVSVQELAWESIKEALNDAGVSQTDIELVVVGSTAYRGIELYPAPIVAEYSGLTGKVPLR-VEAMCATGL 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 138 QAVANIAGGIRNGSYDIGMACGVESM-------SLSNRGNPGNISSRLLESDKARDCLIPMGITSEnvAERFGISrQKQD 210
Cdd:PRK12578 87 AASLTAYTAVASGLVDMAIAVGVDKMtevdtstSLAIGGRGGNYQWEYHFYGTTFPTYYALYATRH--MAVYGTT-EEQM 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 211 AFALASQQKAASAQSKGCFRaeivpvtttvlddkgdrKTITVsqdEGVRPSTTMEGLAKLKpafkdggsttagNSSQVSD 290
Cdd:PRK12578 164 ALVSVKAHKYGAMNPKAHFQ-----------------KPVTV---EEVLKSRAISWPIKLL------------DSCPISD 211
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 291 GAAAVLLARRSKAEELGL--PI----LGVLRSYAVVGVPPDIMGIGPAY-AIPAALQKAGLTVNDIDIFEINEAFASQAL 363
Cdd:PRK12578 212 GSATAIFASEEKVKELKIdsPVwitgIGYANDYAYVARRGEWVGFKATQlAARQAYNMAKVTPNDIEVATVHDAFTIAEI 291
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2074188883 364 YCVEKLGIpAEK-------------------VNPLGGAIALGHPLGCTGARQVVTLLNELK 405
Cdd:PRK12578 292 MGYEDLGF-TEKgkggkfieegqsekggkvgVNLFGGLKAKGHPLGATGLSMIYEITKQLR 351
|
|
| PRK07516 |
PRK07516 |
thiolase domain-containing protein; |
286-431 |
1.27e-08 |
|
thiolase domain-containing protein;
Pssm-ID: 181013 [Multi-domain] Cd Length: 389 Bit Score: 56.49 E-value: 1.27e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 286 SQVSDGAAAVLLARRSKAEELGLPIlgVLRSYAVVGvppDIMGI---------GPAYAIPAALQKAGLTVNDIDIFEINE 356
Cdd:PRK07516 213 SLVSDGAAALVLADAETARALQRAV--RFRARAHVN---DFLPLsrrdplafeGPRRAWQRALAQAGVTLDDLSFVETHD 287
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 357 AFASQALYCVEKLGIPAE------------------KVNPLGGAIALGHPLGCTG-------ARQVVTLLNELKRRGRRA 411
Cdd:PRK07516 288 CFTIAELIEYEAMGLAPPgqgarairegwtakdgklPVNPSGGLKAKGHPIGATGvsmhvlaAMQLTGEAGGMQIPGAKL 367
|
170 180
....*....|....*....|
gi 2074188883 412 YGVVSmcigtgMGAAAVFEY 431
Cdd:PRK07516 368 AGVFN------MGGAAVANY 381
|
|
| PTZ00455 |
PTZ00455 |
3-ketoacyl-CoA thiolase; Provisional |
286-405 |
1.42e-08 |
|
3-ketoacyl-CoA thiolase; Provisional
Pssm-ID: 240424 [Multi-domain] Cd Length: 438 Bit Score: 56.44 E-value: 1.42e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 286 SQVSDGAAAVLLARRSKAEELGL-----PILGVLRSYAVVGV----PPDIMGIGPAY-AIPAALQKAGLTVNDIDIFEIN 355
Cdd:PTZ00455 256 SQVSDGGAGLVLASEEGLQKMGLspndsRLVEIKSLACASGNlyedPPDATRMFTSRaAAQKALSMAGVKPSDLQVAEVH 335
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2074188883 356 EAFASQALYCVEKLGIpAE-------------------KVNPLGGAIALGHPLGCTGARQVVTLLNELK 405
Cdd:PTZ00455 336 DCFTIAELLMYEALGI-AEyghakdlirngatalegriPVNTGGGLLSFGHPVGATGVKQIMEVYRQMK 403
|
|
| PRK06365 |
PRK06365 |
thiolase domain-containing protein; |
338-413 |
6.59e-06 |
|
thiolase domain-containing protein;
Pssm-ID: 235785 [Multi-domain] Cd Length: 430 Bit Score: 47.98 E-value: 6.59e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 338 ALQKAGLT--VNDIDIFEINEAFASQALYCVEKLGI--------------PAEK----VNPLGGAIALGHPLGCTGARQV 397
Cdd:PRK06365 302 AYEMAGITdpLNDLDLIELHDAYTSSEIQTYEDLGLckygeggqfiesgkPELPgklpVNPSGGLLAAGHAVGATGIMQA 381
|
90
....*....|....*.
gi 2074188883 398 VTLLNELKRRGRRAYG 413
Cdd:PRK06365 382 VFMFWQLQGRIKKHFH 397
|
|
| PKS |
cd00833 |
polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different ... |
289-353 |
2.84e-05 |
|
polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or more large multifunctional proteins and iterative type II PKSs, complexes of several monofunctional subunits.
Pssm-ID: 238429 [Multi-domain] Cd Length: 421 Bit Score: 46.01 E-value: 2.84e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2074188883 289 SDGAAAVLLARRSKAEELGLPILGVLRSYAV-------VGVPPDimGIGPAYAIPAALQKAGLTVNDIDIFE 353
Cdd:cd00833 234 GEGVGVVVLKRLSDALRDGDRIYAVIRGSAVnqdgrtkGITAPS--GEAQAALIRRAYARAGVDPSDIDYVE 303
|
|
| ACP_syn_III_C |
pfam08541 |
3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal; This domain is found on ... |
339-431 |
3.27e-05 |
|
3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal; This domain is found on 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III EC:2.3.1.41, the enzyme responsible for initiating the chain of reactions of the fatty acid synthase in plants and bacteria.
Pssm-ID: 430060 Cd Length: 90 Bit Score: 42.10 E-value: 3.27e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 339 LQKAGLTVNDIDIF-------EINEAFAsqalycvEKLGIPAEKVnplggAIALGHpLGCTGARQVVTLLNELKRRGRRA 411
Cdd:pfam08541 1 LEKAGLTPEDIDWFvphqanlRIIDAVA-------KRLGLPPEKV-----VVNLDE-YGNTSAASIPLALDEAVEEGKLK 67
|
90 100
....*....|....*....|...
gi 2074188883 412 YGVVSMCIGTGMG---AAAVFEY 431
Cdd:pfam08541 68 PGDLVLLVGFGAGltwGAALLRW 90
|
|
| PRK08256 |
PRK08256 |
lipid-transfer protein; Provisional |
289-396 |
5.18e-05 |
|
lipid-transfer protein; Provisional
Pssm-ID: 181327 [Multi-domain] Cd Length: 391 Bit Score: 45.27 E-value: 5.18e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 289 SDGAAAVLLARRSKAEELGLPilgvlRSYAVVGV-----------PPDIMG-IGPAYAIPAALQ---KAGLTVNDIDIFE 353
Cdd:PRK08256 214 TCGAAAAIVCSEEFARKHGLD-----RAVEIVAQamttdtpstfdGRSMIDlVGYDMTRAAAQQvyeQAGIGPEDIDVVE 288
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2074188883 354 INEAFASQALYCVEKLGI----PAEK--------------VNPLGGAIALGHPLGCTGARQ 396
Cdd:PRK08256 289 LHDCFSANELLTYEALGLcpegEAEKfiddgdntyggrwvVNPSGGLLSKGHPLGATGLAQ 349
|
|
| PRK07937 |
PRK07937 |
lipid-transfer protein; Provisional |
288-393 |
6.69e-05 |
|
lipid-transfer protein; Provisional
Pssm-ID: 181173 [Multi-domain] Cd Length: 352 Bit Score: 44.68 E-value: 6.69e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 288 VSDGAAAVLLARRSKAEEL--------GL------PILGVlRSYAVVgvppdimgigPAYAIpAALQKAGLTVNDIDIFE 353
Cdd:PRK07937 204 ITDGAAAVVLAAGDRARELrerpawitGIehriesPSLGA-RDLTRS----------PSTAL-AAEAATGGDAGGVDVAE 271
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 2074188883 354 INEAFASQALYCVEKLGIPAE-KVNPLGGAIAlGHPLGCTG 393
Cdd:PRK07937 272 LHAPFTHQELILREALGLGDKtKVNPSGGALA-ANPMFAAG 311
|
|
| FabH |
COG0332 |
3-oxoacyl-[acyl-carrier-protein] synthase III [Lipid transport and metabolism]; 3-oxoacyl- ... |
289-431 |
8.02e-05 |
|
3-oxoacyl-[acyl-carrier-protein] synthase III [Lipid transport and metabolism]; 3-oxoacyl-[acyl-carrier-protein] synthase III is part of the Pathway/BioSystem: Fatty acid biosynthesis
Pssm-ID: 440101 [Multi-domain] Cd Length: 323 Bit Score: 44.33 E-value: 8.02e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 289 SDGAAAVLLarrsKAEELGLPILG-VLRSYA-----------VVGVPPDIMGIGPAY------------------AIPAA 338
Cdd:COG0332 158 GDGAGAVVL----EASEEGPGILGsVLGSDGsgadllvvpagGSRNPPSPVDEGDHYlrmdgrevfkfavrnlpeVIREA 233
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 339 LQKAGLTVNDIDIFEINEAFASQALYCVEKLGIPAEKVnplggaIALGHPLGCTGARQVVTLLNELKRRGRRAYGVVSMC 418
Cdd:COG0332 234 LEKAGLTLDDIDWFIPHQANLRIIEAVAKRLGLPEEKV------VVNIDRYGNTSAASIPLALDEALREGRIKPGDLVLL 307
|
170
....*....|....*.
gi 2074188883 419 IGTGMG---AAAVFEY 431
Cdd:COG0332 308 AGFGAGltwGAAVLRW 323
|
|
| elong_cond_enzymes |
cd00828 |
"elongating" condensing enzymes are a subclass of decarboxylating condensing enzymes, ... |
289-407 |
5.48e-04 |
|
"elongating" condensing enzymes are a subclass of decarboxylating condensing enzymes, including beta-ketoacyl [ACP] synthase, type I and II and polyketide synthases.They are characterized by the utlization of acyl carrier protein (ACP) thioesters as primer substrates, as well as the nature of their active site residues.
Pssm-ID: 238424 [Multi-domain] Cd Length: 407 Bit Score: 42.04 E-value: 5.48e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 289 SDGAAAVLLARRSKAEELGLPILGVLRSYAVVGVPPD----IMGIGPAYAIPAALQKAGLTVNDIDIfeINEAFASQALY 364
Cdd:cd00828 230 AEGAGVLVLERAELALARGAPIYGRVAGTASTTDGAGrsvpAGGKGIARAIRTALAKAGLSLDDLDV--ISAHGTSTPAN 307
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 2074188883 365 CVEKLGIPAEKVNPLGGAIAL-------GHPLGCTGARQVVTLLNELKRR 407
Cdd:cd00828 308 DVAESRAIAEVAGALGAPLPVtaqkalfGHSKGAAGALQLIGALQSLEHG 357
|
|
| PRK06158 |
PRK06158 |
thiolase; Provisional |
288-370 |
7.85e-04 |
|
thiolase; Provisional
Pssm-ID: 180434 [Multi-domain] Cd Length: 384 Bit Score: 41.55 E-value: 7.85e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 288 VSDGAAAVLLARRSKAEELGLPILGVLRSYAVV-----GVPPDIMGIGPAYAIPAALQKAGLTVNDIDIFEINEAFASQA 362
Cdd:PRK06158 208 VTDGAGAVVMVRADRARDLPRPPVYVLGAAAATwhrqiSSMPDLTVTAAAESGPRAFAMAGLTPADIDVVELYDAFTINT 287
|
....*...
gi 2074188883 363 LYCVEKLG 370
Cdd:PRK06158 288 ILFLEDLG 295
|
|
| FabB |
COG0304 |
3-oxoacyl-(acyl-carrier-protein) synthase [Lipid transport and metabolism, Secondary ... |
289-350 |
1.05e-03 |
|
3-oxoacyl-(acyl-carrier-protein) synthase [Lipid transport and metabolism, Secondary metabolites biosynthesis, transport and catabolism]; 3-oxoacyl-(acyl-carrier-protein) synthase is part of the Pathway/BioSystem: Fatty acid biosynthesis
Pssm-ID: 440073 [Multi-domain] Cd Length: 409 Bit Score: 41.23 E-value: 1.05e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2074188883 289 SDGAAAVLLARRSKAEELGLPILGVLRSYA-------VVGVPPDimGIGPAYAIPAALQKAGLTVNDID 350
Cdd:COG0304 230 GEGAGVLVLEELEHAKARGAKIYAEVVGYGassdayhITAPAPD--GEGAARAMRAALKDAGLSPEDID 296
|
|
| KAS_I_II |
cd00834 |
Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible ... |
289-394 |
1.86e-03 |
|
Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen condensation of malonyl-acyl carrier protein (ACP) with acyl-ACP.
Pssm-ID: 238430 [Multi-domain] Cd Length: 406 Bit Score: 40.21 E-value: 1.86e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2074188883 289 SDGAAAVLLARRSKAEELGLPILGVLRSYAVVG-----VPPDIMGIGPAYAIPAALQKAGLTVNDIDIfeIN-------- 355
Cdd:cd00834 230 GEGAGVLVLESLEHAKARGAKIYAEILGYGASSdayhiTAPDPDGEGAARAMRAALADAGLSPEDIDY--INahgtstpl 307
|
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 2074188883 356 ----EAFASQALYCVEKLGIPaekVNPLGGAIalGHPLGCTGA 394
Cdd:cd00834 308 ndaaESKAIKRVFGEHAKKVP---VSSTKSMT--GHLLGAAGA 345
|
|
| PRK07103 |
PRK07103 |
polyketide beta-ketoacyl:acyl carrier protein synthase; Validated |
291-350 |
6.15e-03 |
|
polyketide beta-ketoacyl:acyl carrier protein synthase; Validated
Pssm-ID: 180839 [Multi-domain] Cd Length: 410 Bit Score: 38.86 E-value: 6.15e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2074188883 291 GAAAVLLARRSKAEELGLPILGVLRSYAVV-----GVPPDImgIGPAYAIPAALQKAGLTVNDID 350
Cdd:PRK07103 240 ACGAVVLESAESARRRGARPYAKLLGWSMRldanrGPDPSL--EGEMRVIRAALRRAGLGPEDID 302
|
|
| |
