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Conserved domains on  [gi|66793411|ref|NP_035532|]
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sodium-dependent phosphate transport protein 2B [Mus musculus]

Protein Classification

sodium-dependent phosphate transport protein 2( domain architecture ID 11490082)

sodium-dependent phosphate transport protein 2 may be involved in actively transporting phosphate into cells via Na(+) cotransport in the renal brush border membrane

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
2a58 TIGR01013
Phosphate:Na+ Symporter (PNaS) Family; [Transport and binding proteins, Cations and iron ...
105-604 1.01e-174

Phosphate:Na+ Symporter (PNaS) Family; [Transport and binding proteins, Cations and iron carrying compounds]


:

Pssm-ID: 162157 [Multi-domain]  Cd Length: 456  Bit Score: 506.71  E-value: 1.01e-174
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66793411   105 LGFLYLFVCSLDVLSSAFQLVGGKVAGQFFSNNSIMSNPVAGLVIGVLVTVMVQSSSTSSSIIVSMVASSLLTVRAAIPI 184
Cdd:TIGR01013   1 LVLLFVFVCSLAVLSAAFILLGAKVGGAIFADILITDNPWASPLLGFLGTVLLQSSSTSRSIVVGMVSAGLLLVLLAIPL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66793411   185 IMGANIGTSITNTIVALMQAGDRNEFRRAFAGATVHDFFNWLSVFVLLPLEAATHYLEILTNLVLETFKFQNGEDAPDIL 264
Cdd:TIGR01013  81 IMGANIGSSVTNAIVAIMQSGDRAWFRRAFIGATVADIFNSSLALVLLPLELTTGGIESVTLLVVLVFGANGGGDAPDLL 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66793411   265 KVITDPFTKLIIQLDKKVIQQIAmgdsAAQNKSLIKIWCKsitnvtemnvtvpstdncTSPSYCWTDGiqtwtiqnvtqk 344
Cdd:TIGR01013 161 NSLTAPATALIVQLDNLIIRLIG----SLLILPLIDILAS------------------TLSSLPVPES------------ 206
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66793411   345 eNIAKCQHIFVNfslpdlaVGIILLTVSLVVLCGCLIMIVKLLGSVLRGQVATVIKKTLNTDFPFPFAWLTGYLAILVGA 424
Cdd:TIGR01013 207 -NLPIEAHIFVN-------VGLILLALPFVRLCARLILVVIPLNSLLDGQVAPVILDVINLDTPVPFLWVTGYEALLVGD 278
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66793411   425 GMTFIVQSSSVFTSAMTPLIGIGVISIERAYPLTLGSNIGTTTTAILAALASPGNTLRSSLQIALCHFFFNISGILLWYP 504
Cdd:TIGR01013 279 AMTFIIQSSSVFTSALTPLVGKGVISLERAYPLVLGSNIGTTLTAVLAALLSEDEKRRSALQIAYCHNLFNISGIVLFYP 358
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66793411   505 IPFTRLPIRLAKGLGNISAKYRWFAVFYLIFFFFVTPLTVFGLSLAGWPVLVGVGVPIILLLLLVLCLRMLQFRCPRilP 584
Cdd:TIGR01013 359 LPCTRKPIAAARGFGDDGSKYRWFLIVYLVLNFLLAPSLLFGLDLNLARRLVGVKIPFRILELFSSLLHVLQLRCPR--P 436
                         490       500
                  ....*....|....*....|
gi 66793411   585 LKLRDWNFLPLWMHSLKPWD 604
Cdd:TIGR01013 437 QSLQTWSFLPDWLRSLKRLD 456
 
Name Accession Description Interval E-value
2a58 TIGR01013
Phosphate:Na+ Symporter (PNaS) Family; [Transport and binding proteins, Cations and iron ...
105-604 1.01e-174

Phosphate:Na+ Symporter (PNaS) Family; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 162157 [Multi-domain]  Cd Length: 456  Bit Score: 506.71  E-value: 1.01e-174
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66793411   105 LGFLYLFVCSLDVLSSAFQLVGGKVAGQFFSNNSIMSNPVAGLVIGVLVTVMVQSSSTSSSIIVSMVASSLLTVRAAIPI 184
Cdd:TIGR01013   1 LVLLFVFVCSLAVLSAAFILLGAKVGGAIFADILITDNPWASPLLGFLGTVLLQSSSTSRSIVVGMVSAGLLLVLLAIPL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66793411   185 IMGANIGTSITNTIVALMQAGDRNEFRRAFAGATVHDFFNWLSVFVLLPLEAATHYLEILTNLVLETFKFQNGEDAPDIL 264
Cdd:TIGR01013  81 IMGANIGSSVTNAIVAIMQSGDRAWFRRAFIGATVADIFNSSLALVLLPLELTTGGIESVTLLVVLVFGANGGGDAPDLL 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66793411   265 KVITDPFTKLIIQLDKKVIQQIAmgdsAAQNKSLIKIWCKsitnvtemnvtvpstdncTSPSYCWTDGiqtwtiqnvtqk 344
Cdd:TIGR01013 161 NSLTAPATALIVQLDNLIIRLIG----SLLILPLIDILAS------------------TLSSLPVPES------------ 206
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66793411   345 eNIAKCQHIFVNfslpdlaVGIILLTVSLVVLCGCLIMIVKLLGSVLRGQVATVIKKTLNTDFPFPFAWLTGYLAILVGA 424
Cdd:TIGR01013 207 -NLPIEAHIFVN-------VGLILLALPFVRLCARLILVVIPLNSLLDGQVAPVILDVINLDTPVPFLWVTGYEALLVGD 278
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66793411   425 GMTFIVQSSSVFTSAMTPLIGIGVISIERAYPLTLGSNIGTTTTAILAALASPGNTLRSSLQIALCHFFFNISGILLWYP 504
Cdd:TIGR01013 279 AMTFIIQSSSVFTSALTPLVGKGVISLERAYPLVLGSNIGTTLTAVLAALLSEDEKRRSALQIAYCHNLFNISGIVLFYP 358
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66793411   505 IPFTRLPIRLAKGLGNISAKYRWFAVFYLIFFFFVTPLTVFGLSLAGWPVLVGVGVPIILLLLLVLCLRMLQFRCPRilP 584
Cdd:TIGR01013 359 LPCTRKPIAAARGFGDDGSKYRWFLIVYLVLNFLLAPSLLFGLDLNLARRLVGVKIPFRILELFSSLLHVLQLRCPR--P 436
                         490       500
                  ....*....|....*....|
gi 66793411   585 LKLRDWNFLPLWMHSLKPWD 604
Cdd:TIGR01013 437 QSLQTWSFLPDWLRSLKRLD 456
NptA COG1283
Na+/phosphate symporter [Inorganic ion transport and metabolism];
418-542 5.02e-19

Na+/phosphate symporter [Inorganic ion transport and metabolism];


Pssm-ID: 440894 [Multi-domain]  Cd Length: 540  Bit Score: 91.01  E-value: 5.02e-19
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66793411 418 LAILVGAGMTFIVQSSSVFTS-AMTpLIGIGVISIERAYPLTLGSNIGTTTTAILAALASPGNTLRsslqIALCHFFFNI 496
Cdd:COG1283 176 LGVLVGALLTALVQSSSATVGlLLA-LAAQGLIPLEAALALVLGANIGTTITALLASIGANVAARR----AALAHLLFNL 250
                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|...
gi 66793411 497 SGILLWYPI--PFTRLpirLAKGLGNISAKYRWFAVFY-----LIFFFFVTPL 542
Cdd:COG1283 251 IGVLIFLPLlpPFAAL---VAWLSPDPARQIANFHTLFnllnaLLFLPFIGPL 300
Na_Pi_cotrans pfam02690
Na+/Pi-cotransporter; This is a family of mainly mammalian type II renal Na+/Pi-cotransporters ...
110-201 3.50e-14

Na+/Pi-cotransporter; This is a family of mainly mammalian type II renal Na+/Pi-cotransporters with other related sequences from lower eukaryotes and bacteria some of which are also Na+/Pi-cotransporters. In the kidney the type II renal Na+/Pi-cotransporters protein allows re-absorption of filtered Pi in the proximal tubule.


Pssm-ID: 460653 [Multi-domain]  Cd Length: 137  Bit Score: 69.74  E-value: 3.50e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66793411   110 LFVCSLDVLSSAFQLVGGKVAGQFFSnnSIMSNPVAGLVIGVLVTVMVQSSSTSSSIIVSMVASSLLTVRAAIPIIMGAN 189
Cdd:pfam02690   1 LFLFGMKLMSDGLQKLAGGRLRRILE--KLTSNPLKGFLVGLLVTALLQSSSATTVMVVGFVNAGLLTLAQALGVIMGAN 78
                          90
                  ....*....|..
gi 66793411   190 IGTSITNTIVAL 201
Cdd:pfam02690  79 IGTTVTAQLIAF 90
Na_Pi_symport NF037997
Na/Pi symporter; Proteins of this family belong to the Phosphate:Na+ Symporter (PNaS) ...
405-505 6.93e-10

Na/Pi symporter; Proteins of this family belong to the Phosphate:Na+ Symporter (PNaS) superfamily.


Pssm-ID: 411591 [Multi-domain]  Cd Length: 294  Bit Score: 60.69  E-value: 6.93e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66793411  405 TDFPFPFAWLT-----GYLAILVGAGMTFIVQSSSVFTSAMTPLIGIGVISIERAYPLTLGSNIGTTTTAILAALASPgn 479
Cdd:NF037997 148 TSLPFVHSLLEstnesLLLALLIGTVLTAIIQSSSATTGITMSFLNEGILTLPAGIAIMLGANIGTCITALLASIGSG-- 225
                         90       100
                 ....*....|....*....|....*.
gi 66793411  480 tlRSSLQIALCHFFFNISGILLWYPI 505
Cdd:NF037997 226 --KEAKLTAYAHIWLNVLGVLLFLPF 249
Na_Pi_symport NF037997
Na/Pi symporter; Proteins of this family belong to the Phosphate:Na+ Symporter (PNaS) ...
104-234 3.97e-06

Na/Pi symporter; Proteins of this family belong to the Phosphate:Na+ Symporter (PNaS) superfamily.


Pssm-ID: 411591 [Multi-domain]  Cd Length: 294  Bit Score: 49.14  E-value: 3.97e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66793411  104 LLGFLYLFVCSldvlsSAFQLVGGKVAGQFFSNNSIMS---NPVAGLVIGVLVTVMVQSSSTSSSIIVSMVASSLLTVRA 180
Cdd:NF037997 127 LFGLGAIFTAM-----RGFESLAGPLTSLPFVHSLLEStneSLLLALLIGTVLTAIIQSSSATTGITMSFLNEGILTLPA 201
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 66793411  181 AIPIIMGANIGTSITNTIVALmqaGDRNEFRR-AFAgatvHDFFNWLSVFVLLPL 234
Cdd:NF037997 202 GIAIMLGANIGTCITALLASI---GSGKEAKLtAYA----HIWLNVLGVLLFLPF 249
Na_Pi_symport NF037997
Na/Pi symporter; Proteins of this family belong to the Phosphate:Na+ Symporter (PNaS) ...
101-201 5.48e-05

Na/Pi symporter; Proteins of this family belong to the Phosphate:Na+ Symporter (PNaS) superfamily.


Pssm-ID: 411591 [Multi-domain]  Cd Length: 294  Bit Score: 45.67  E-value: 5.48e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66793411  101 FILLLGflyLFVCSLDVLSSA-FQLVGGKVAGQFFSnnsIMSNPVAGLVIGVLVTVMVQSSSTSSSIIVSMVASSLLTVR 179
Cdd:NF037997   1 FALYIA---IFLLGMTVLRSGlFNLSGHKLKTWLLK---FTDTPLKGFLTGTVITAILQSSSAVMVLTVGLVSAGILTFR 74
                         90       100
                 ....*....|....*....|..
gi 66793411  180 AAIPIIMGANIGTSITNTIVAL 201
Cdd:NF037997  75 QSIGIILGTNIGTTFTTEFITF 96
 
Name Accession Description Interval E-value
2a58 TIGR01013
Phosphate:Na+ Symporter (PNaS) Family; [Transport and binding proteins, Cations and iron ...
105-604 1.01e-174

Phosphate:Na+ Symporter (PNaS) Family; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 162157 [Multi-domain]  Cd Length: 456  Bit Score: 506.71  E-value: 1.01e-174
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66793411   105 LGFLYLFVCSLDVLSSAFQLVGGKVAGQFFSNNSIMSNPVAGLVIGVLVTVMVQSSSTSSSIIVSMVASSLLTVRAAIPI 184
Cdd:TIGR01013   1 LVLLFVFVCSLAVLSAAFILLGAKVGGAIFADILITDNPWASPLLGFLGTVLLQSSSTSRSIVVGMVSAGLLLVLLAIPL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66793411   185 IMGANIGTSITNTIVALMQAGDRNEFRRAFAGATVHDFFNWLSVFVLLPLEAATHYLEILTNLVLETFKFQNGEDAPDIL 264
Cdd:TIGR01013  81 IMGANIGSSVTNAIVAIMQSGDRAWFRRAFIGATVADIFNSSLALVLLPLELTTGGIESVTLLVVLVFGANGGGDAPDLL 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66793411   265 KVITDPFTKLIIQLDKKVIQQIAmgdsAAQNKSLIKIWCKsitnvtemnvtvpstdncTSPSYCWTDGiqtwtiqnvtqk 344
Cdd:TIGR01013 161 NSLTAPATALIVQLDNLIIRLIG----SLLILPLIDILAS------------------TLSSLPVPES------------ 206
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66793411   345 eNIAKCQHIFVNfslpdlaVGIILLTVSLVVLCGCLIMIVKLLGSVLRGQVATVIKKTLNTDFPFPFAWLTGYLAILVGA 424
Cdd:TIGR01013 207 -NLPIEAHIFVN-------VGLILLALPFVRLCARLILVVIPLNSLLDGQVAPVILDVINLDTPVPFLWVTGYEALLVGD 278
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66793411   425 GMTFIVQSSSVFTSAMTPLIGIGVISIERAYPLTLGSNIGTTTTAILAALASPGNTLRSSLQIALCHFFFNISGILLWYP 504
Cdd:TIGR01013 279 AMTFIIQSSSVFTSALTPLVGKGVISLERAYPLVLGSNIGTTLTAVLAALLSEDEKRRSALQIAYCHNLFNISGIVLFYP 358
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66793411   505 IPFTRLPIRLAKGLGNISAKYRWFAVFYLIFFFFVTPLTVFGLSLAGWPVLVGVGVPIILLLLLVLCLRMLQFRCPRilP 584
Cdd:TIGR01013 359 LPCTRKPIAAARGFGDDGSKYRWFLIVYLVLNFLLAPSLLFGLDLNLARRLVGVKIPFRILELFSSLLHVLQLRCPR--P 436
                         490       500
                  ....*....|....*....|
gi 66793411   585 LKLRDWNFLPLWMHSLKPWD 604
Cdd:TIGR01013 437 QSLQTWSFLPDWLRSLKRLD 456
NptA COG1283
Na+/phosphate symporter [Inorganic ion transport and metabolism];
418-542 5.02e-19

Na+/phosphate symporter [Inorganic ion transport and metabolism];


Pssm-ID: 440894 [Multi-domain]  Cd Length: 540  Bit Score: 91.01  E-value: 5.02e-19
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66793411 418 LAILVGAGMTFIVQSSSVFTS-AMTpLIGIGVISIERAYPLTLGSNIGTTTTAILAALASPGNTLRsslqIALCHFFFNI 496
Cdd:COG1283 176 LGVLVGALLTALVQSSSATVGlLLA-LAAQGLIPLEAALALVLGANIGTTITALLASIGANVAARR----AALAHLLFNL 250
                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|...
gi 66793411 497 SGILLWYPI--PFTRLpirLAKGLGNISAKYRWFAVFY-----LIFFFFVTPL 542
Cdd:COG1283 251 IGVLIFLPLlpPFAAL---VAWLSPDPARQIANFHTLFnllnaLLFLPFIGPL 300
Na_Pi_cotrans pfam02690
Na+/Pi-cotransporter; This is a family of mainly mammalian type II renal Na+/Pi-cotransporters ...
110-201 3.50e-14

Na+/Pi-cotransporter; This is a family of mainly mammalian type II renal Na+/Pi-cotransporters with other related sequences from lower eukaryotes and bacteria some of which are also Na+/Pi-cotransporters. In the kidney the type II renal Na+/Pi-cotransporters protein allows re-absorption of filtered Pi in the proximal tubule.


Pssm-ID: 460653 [Multi-domain]  Cd Length: 137  Bit Score: 69.74  E-value: 3.50e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66793411   110 LFVCSLDVLSSAFQLVGGKVAGQFFSnnSIMSNPVAGLVIGVLVTVMVQSSSTSSSIIVSMVASSLLTVRAAIPIIMGAN 189
Cdd:pfam02690   1 LFLFGMKLMSDGLQKLAGGRLRRILE--KLTSNPLKGFLVGLLVTALLQSSSATTVMVVGFVNAGLLTLAQALGVIMGAN 78
                          90
                  ....*....|..
gi 66793411   190 IGTSITNTIVAL 201
Cdd:pfam02690  79 IGTTVTAQLIAF 90
NptA COG1283
Na+/phosphate symporter [Inorganic ion transport and metabolism];
96-234 1.37e-10

Na+/phosphate symporter [Inorganic ion transport and metabolism];


Pssm-ID: 440894 [Multi-domain]  Cd Length: 540  Bit Score: 64.43  E-value: 1.37e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66793411  96 QGVGKFILLLGFLYLfvcSLDVLSSAFQ-LVGGKVAGQFFSnnSIMSNPVAGLVIGVLVTVMVQSSSTSSSIIVSMVASS 174
Cdd:COG1283 131 RQIGRILIGFGLLFL---GLDLMSEAMEpLRDSPAFRALLA--SLSGNPLLGVLVGALLTALVQSSSATVGLLLALAAQG 205
                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|
gi 66793411 175 LLTVRAAIPIIMGANIGTSITNTIVALmqAGDRNEfRRAfagATVHDFFNWLSVFVLLPL 234
Cdd:COG1283 206 LIPLEAALALVLGANIGTTITALLASI--GANVAA-RRA---ALAHLLFNLIGVLIFLPL 259
Na_Pi_cotrans pfam02690
Na+/Pi-cotransporter; This is a family of mainly mammalian type II renal Na+/Pi-cotransporters ...
417-474 1.75e-10

Na+/Pi-cotransporter; This is a family of mainly mammalian type II renal Na+/Pi-cotransporters with other related sequences from lower eukaryotes and bacteria some of which are also Na+/Pi-cotransporters. In the kidney the type II renal Na+/Pi-cotransporters protein allows re-absorption of filtered Pi in the proximal tubule.


Pssm-ID: 460653 [Multi-domain]  Cd Length: 137  Bit Score: 59.34  E-value: 1.75e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 66793411   417 YLAILVGAGMTFIVQSSSVFTSAMTPLIGIGVISIERAYPLTLGSNIGTTTTAILAAL 474
Cdd:pfam02690  33 LKGFLVGLLVTALLQSSSATTVMVVGFVNAGLLTLAQALGVIMGANIGTTVTAQLIAF 90
Na_Pi_symport NF037997
Na/Pi symporter; Proteins of this family belong to the Phosphate:Na+ Symporter (PNaS) ...
405-505 6.93e-10

Na/Pi symporter; Proteins of this family belong to the Phosphate:Na+ Symporter (PNaS) superfamily.


Pssm-ID: 411591 [Multi-domain]  Cd Length: 294  Bit Score: 60.69  E-value: 6.93e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66793411  405 TDFPFPFAWLT-----GYLAILVGAGMTFIVQSSSVFTSAMTPLIGIGVISIERAYPLTLGSNIGTTTTAILAALASPgn 479
Cdd:NF037997 148 TSLPFVHSLLEstnesLLLALLIGTVLTAIIQSSSATTGITMSFLNEGILTLPAGIAIMLGANIGTCITALLASIGSG-- 225
                         90       100
                 ....*....|....*....|....*.
gi 66793411  480 tlRSSLQIALCHFFFNISGILLWYPI 505
Cdd:NF037997 226 --KEAKLTAYAHIWLNVLGVLLFLPF 249
NptA COG1283
Na+/phosphate symporter [Inorganic ion transport and metabolism];
418-474 5.10e-07

Na+/phosphate symporter [Inorganic ion transport and metabolism];


Pssm-ID: 440894 [Multi-domain]  Cd Length: 540  Bit Score: 52.87  E-value: 5.10e-07
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*...
gi 66793411 418 LAILVGAGMTFIVQSSSVfTSAMT-PLIGIGVISIERAYPLTLGSNIGTTTTAILAAL 474
Cdd:COG1283  49 KGVLAGALVTALLQSSSA-TTVMVvGFVNAGLMTLAQALGVILGANIGTTLTAQLIAF 105
NaPi_cotrn_rel TIGR00704
Na/Pi-cotransporter; This model describes essentially the full length of an uncharacterized ...
362-542 1.50e-06

Na/Pi-cotransporter; This model describes essentially the full length of an uncharacterized protein from Bacillus subtilis and correponding lengths of longer proteins from E. coli and Treponema pallidum. PSI-BLAST analysis converges to demonstrate homology to one other group of proteins, type II sodium/phosphate (Na/Pi) cotransporters. A well-conserved repeated domain in this family, approximately 60 residues in length, is also repeated in the Na/Pi cotransporters, although with greater spacing between the repeats. The two families share additional homology in the region after the first repeat, share the properly of having extensive hydrophobic regions, and may be similar in function. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273225 [Multi-domain]  Cd Length: 308  Bit Score: 50.69  E-value: 1.50e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66793411   362 LAVGIILLtvslvvlcgCLIMIVKLLGSVLRGQVATVIKKTLNTDFpfpfawltgYLAILVGAGMTFIVQSSSVFTSAMT 441
Cdd:TIGR00704 135 IGLGIIFF---------AIEGFSHAAGPITKAKGGADIFAHLNDDI---------LLAALIGAMFAAIIHSSLAAIGILA 196
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66793411   442 PLIGIGVISIERAYPLTLGSNIGTTTTAILAALASPGntlrSSLQIALCHFFFNISGILLwyPIPFTRLpirLAKGLGNI 521
Cdd:TIGR00704 197 SFMAAGIIGFPQALCLVIGANIGSCILAMLAASAAGA----AAKQTALAHLLFKLLGSAI--ILPFLHA---AAEFMEKL 267
                         170       180
                  ....*....|....*....|.
gi 66793411   522 SAKYRWFAVFYLIFFFFVTPL 542
Cdd:TIGR00704 268 SLDKAEKIAHFHLFFNLVRAL 288
Na_Pi_symport NF037997
Na/Pi symporter; Proteins of this family belong to the Phosphate:Na+ Symporter (PNaS) ...
104-234 3.97e-06

Na/Pi symporter; Proteins of this family belong to the Phosphate:Na+ Symporter (PNaS) superfamily.


Pssm-ID: 411591 [Multi-domain]  Cd Length: 294  Bit Score: 49.14  E-value: 3.97e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66793411  104 LLGFLYLFVCSldvlsSAFQLVGGKVAGQFFSNNSIMS---NPVAGLVIGVLVTVMVQSSSTSSSIIVSMVASSLLTVRA 180
Cdd:NF037997 127 LFGLGAIFTAM-----RGFESLAGPLTSLPFVHSLLEStneSLLLALLIGTVLTAIIQSSSATTGITMSFLNEGILTLPA 201
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 66793411  181 AIPIIMGANIGTSITNTIVALmqaGDRNEFRR-AFAgatvHDFFNWLSVFVLLPL 234
Cdd:NF037997 202 GIAIMLGANIGTCITALLASI---GSGKEAKLtAYA----HIWLNVLGVLLFLPF 249
Na_Pi_symport NF037997
Na/Pi symporter; Proteins of this family belong to the Phosphate:Na+ Symporter (PNaS) ...
101-201 5.48e-05

Na/Pi symporter; Proteins of this family belong to the Phosphate:Na+ Symporter (PNaS) superfamily.


Pssm-ID: 411591 [Multi-domain]  Cd Length: 294  Bit Score: 45.67  E-value: 5.48e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 66793411  101 FILLLGflyLFVCSLDVLSSA-FQLVGGKVAGQFFSnnsIMSNPVAGLVIGVLVTVMVQSSSTSSSIIVSMVASSLLTVR 179
Cdd:NF037997   1 FALYIA---IFLLGMTVLRSGlFNLSGHKLKTWLLK---FTDTPLKGFLTGTVITAILQSSSAVMVLTVGLVSAGILTFR 74
                         90       100
                 ....*....|....*....|..
gi 66793411  180 AAIPIIMGANIGTSITNTIVAL 201
Cdd:NF037997  75 QSIGIILGTNIGTTFTTEFITF 96
NaPi_cotrn_rel TIGR00704
Na/Pi-cotransporter; This model describes essentially the full length of an uncharacterized ...
418-469 5.94e-04

Na/Pi-cotransporter; This model describes essentially the full length of an uncharacterized protein from Bacillus subtilis and correponding lengths of longer proteins from E. coli and Treponema pallidum. PSI-BLAST analysis converges to demonstrate homology to one other group of proteins, type II sodium/phosphate (Na/Pi) cotransporters. A well-conserved repeated domain in this family, approximately 60 residues in length, is also repeated in the Na/Pi cotransporters, although with greater spacing between the repeats. The two families share additional homology in the region after the first repeat, share the properly of having extensive hydrophobic regions, and may be similar in function. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273225 [Multi-domain]  Cd Length: 308  Bit Score: 42.60  E-value: 5.94e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 66793411   418 LAILVGAGMTFIVQSSSVFTSAMTPLIGIGVISIERAYPLTLGSNIGTTTTA 469
Cdd:TIGR00704  46 KAFCAGIGFTAILQSSNAFMMIVIGFVAADLLAFAPAIPIILGADVGSAFMA 97
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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