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Conserved domains on  [gi|6754696|ref|NP_034928|]
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macrophage migration inhibitory factor [Mus musculus]

Protein Classification

tautomerase family protein; 4-oxalocrotonate tautomerase family protein( domain architecture ID 10471872)

tautomerase family protein similar to Homo sapiens macrophage migration inhibitory factor and D-dopachrome decarboxylase-like protein| 4-oxalocrotonate tautomerase family protein such as 4-oxalocrotonate tautomerase, also called 2-hydroxymuconate tautomerase, which catalyzes the ketonization of 2-hydroxymuconate stereoselectively to yield 2-oxo-3-hexenedioate

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
MIF pfam01187
Macrophage migration inhibitory factor (MIF);
2-115 3.98e-67

Macrophage migration inhibitory factor (MIF);


:

Pssm-ID: 395945  Cd Length: 114  Bit Score: 197.66  E-value: 3.98e-67
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6754696      2 PMFIVNTNVPRASVPEGFLSELTQQLAQATGKPAQYIAVHVVPDQLMTFSGTNDPCALCSLHSIGKIGGAQNRNYSKLLC 81
Cdd:pfam01187   1 PMFTIDTNLPANSVPAGLEKRLTAALAKALGKPADRIAVHIRPGQAMVFGGSTDPCAVCSIKSIGVVGAEQNRSHSALLF 80

                          90       100       110
                  ....*....|....*....|....*....|....
gi 6754696     82 GLLSDRLHISPDRVYINYYDMNAANVGWNGSTFA 115
Cdd:pfam01187  81 KFLTKELGLPKDRIYIRFFDLEAAQVGFNGTTFA 114
 
Name Accession Description Interval E-value
MIF pfam01187
Macrophage migration inhibitory factor (MIF);
2-115 3.98e-67

Macrophage migration inhibitory factor (MIF);


Pssm-ID: 395945  Cd Length: 114  Bit Score: 197.66  E-value: 3.98e-67
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6754696      2 PMFIVNTNVPRASVPEGFLSELTQQLAQATGKPAQYIAVHVVPDQLMTFSGTNDPCALCSLHSIGKIGGAQNRNYSKLLC 81
Cdd:pfam01187   1 PMFTIDTNLPANSVPAGLEKRLTAALAKALGKPADRIAVHIRPGQAMVFGGSTDPCAVCSIKSIGVVGAEQNRSHSALLF 80

                          90       100       110
                  ....*....|....*....|....*....|....
gi 6754696     82 GLLSDRLHISPDRVYINYYDMNAANVGWNGSTFA 115
Cdd:pfam01187  81 KFLTKELGLPKDRIYIRFFDLEAAQVGFNGTTFA 114
PTZ00397 PTZ00397
macrophage migration inhibition factor-like protein; Provisional
 1-114 1.68e-20

macrophage migration inhibition factor-like protein; Provisional


Pssm-ID: 240401  Cd Length: 116  Bit Score: 79.49  E-value: 1.68e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6754696     1 MPMFIVNTNV--PRASVpEGFLSELTQQLAQATGKPAQYIAVHVVPDQLMTFSGTNDPCALCSLHSIGKIGGAQNRNYSK 78
Cdd:PTZ00397   1 MPCCQVSTNVnaTDDQA-DAALSDIENAIADVLGKPLSYIMSGYDYQKHMRFGGSHDGCCFVRVTSIGGISRSNNSSIAA 79

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 6754696    79 LLCGLLSDRLHISPDRVYINYYDMNAANVGWNGSTF 114
Cdd:PTZ00397  80 AITKILASHLKVKSERVYIEFKDCSAQNWAFNGSTF 115
 
Name Accession Description Interval E-value
MIF pfam01187
Macrophage migration inhibitory factor (MIF);
2-115 3.98e-67

Macrophage migration inhibitory factor (MIF);


Pssm-ID: 395945  Cd Length: 114  Bit Score: 197.66  E-value: 3.98e-67
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6754696      2 PMFIVNTNVPRASVPEGFLSELTQQLAQATGKPAQYIAVHVVPDQLMTFSGTNDPCALCSLHSIGKIGGAQNRNYSKLLC 81
Cdd:pfam01187   1 PMFTIDTNLPANSVPAGLEKRLTAALAKALGKPADRIAVHIRPGQAMVFGGSTDPCAVCSIKSIGVVGAEQNRSHSALLF 80

                          90       100       110
                  ....*....|....*....|....*....|....
gi 6754696     82 GLLSDRLHISPDRVYINYYDMNAANVGWNGSTFA 115
Cdd:pfam01187  81 KFLTKELGLPKDRIYIRFFDLEAAQVGFNGTTFA 114
PTZ00397 PTZ00397
macrophage migration inhibition factor-like protein; Provisional
 1-114 1.68e-20

macrophage migration inhibition factor-like protein; Provisional


Pssm-ID: 240401  Cd Length: 116  Bit Score: 79.49  E-value: 1.68e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6754696     1 MPMFIVNTNV--PRASVpEGFLSELTQQLAQATGKPAQYIAVHVVPDQLMTFSGTNDPCALCSLHSIGKIGGAQNRNYSK 78
Cdd:PTZ00397   1 MPCCQVSTNVnaTDDQA-DAALSDIENAIADVLGKPLSYIMSGYDYQKHMRFGGSHDGCCFVRVTSIGGISRSNNSSIAA 79

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 6754696    79 LLCGLLSDRLHISPDRVYINYYDMNAANVGWNGSTF 114
Cdd:PTZ00397  80 AITKILASHLKVKSERVYIEFKDCSAQNWAFNGSTF 115
PTZ00450 PTZ00450
macrophage migration inhibitory factor-like protein; Provisional
 32-114 7.10e-07

macrophage migration inhibitory factor-like protein; Provisional


Pssm-ID: 185629  Cd Length: 113  Bit Score: 44.24  E-value: 7.10e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6754696    32 GKPAQYIAVHVVPDQLMTFSGTNDPCALCSLHSIGKIGGAQNRNYSKLLCGLLSDRLHISPDRVYINYYdmNAANVGWNG 111
Cdd:PTZ00450  33 GKPEDFVMTAFSDSTPMSFQGSTAPAAYVRVEAWGEYAPSKPKMMTPRITAAITKECGIPAERIYVFYY--STKHCGWNG 110


                 ...
gi 6754696   112 STF 114
Cdd:PTZ00450 111 TNF 113
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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