|
Name |
Accession |
Description |
Interval |
E-value |
| Gal-bind_lectin |
smart00908 |
Galactoside-binding lectin; Animal lectins display a wide variety of architectures. They are ... |
137-258 |
1.22e-54 |
|
Galactoside-binding lectin; Animal lectins display a wide variety of architectures. They are classified according to the carbohydrate-recognition domain (CRD) of which there are two main types, S-type and C-type. Galectins (previously S-lectins) bind exclusively beta-galactosides like lactose. They do not require metal ions for activity. Galectins are found predominantly, but not exclusively in mammals. Their function is unclear. They are developmentally regulated and may be involved in differentiation, cellular regulation and tissue construction.
Pssm-ID: 214904 Cd Length: 122 Bit Score: 172.01 E-value: 1.22e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859580 137 PGGVMPRMLITIMGTVKPNANRIVLDFRRG--NDVAFHFNPRFNENnrrVIVCNTKQDNNWGKEERQSAFPFESGKPFKI 214
Cdd:smart00908 1 PGGLSPGSSITIRGIVLPDAKRFSINLQCGpnADIALHFNPRFDEG---TIVRNSKQNGKWGKEERSGGFPFQPGQPFEL 77
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 33859580 215 QVLVEADHFKVAVNDAHLLQYNHRMKnLREISQLGISGDITLTS 258
Cdd:smart00908 78 EILVEEDEFKVAVNGQHFLEFPHRLP-LESIDTLEISGDVQLTS 120
|
|
| GLECT |
cd00070 |
Galectin/galactose-binding lectin. This domain exclusively binds beta-galactosides, such as ... |
131-258 |
7.17e-54 |
|
Galectin/galactose-binding lectin. This domain exclusively binds beta-galactosides, such as lactose, and does not require metal ions for activity. GLECT domains occur as homodimers or tandemly repeated domains. They are developmentally regulated and may be involved in differentiation, cell-cell interaction and cellular regulation.
Pssm-ID: 238025 Cd Length: 127 Bit Score: 170.51 E-value: 7.17e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859580 131 PYDLPLPGGVMPRMLITIMGTVKPNANRIVLDFRRGN-DVAFHFNPRFNENnrrVIVCNTKQDNNWGKEERQSAFPFESG 209
Cdd:cd00070 1 PYKLPLPGGLKPGSTLTVKGRVLPNAKRFSINLGTGSsDIALHFNPRFDEN---VIVRNSFLNGNWGPEERSGGFPFQPG 77
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 33859580 210 KPFKIQVLVEADHFKVAVNDAHLLQYNHRMKnLREISQLGISGDITLTS 258
Cdd:cd00070 78 QPFELTILVEEDKFQIFVNGQHFFSFPHRLP-LESIDYLSINGDVSLTS 125
|
|
| Gal-bind_lectin |
pfam00337 |
Galactoside-binding lectin; This family contains galactoside binding lectins. The family also ... |
137-258 |
1.03e-49 |
|
Galactoside-binding lectin; This family contains galactoside binding lectins. The family also includes enzymes such as human eosinophil lysophospholipase (EC:3.1.1.5).
Pssm-ID: 459768 Cd Length: 124 Bit Score: 159.73 E-value: 1.03e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859580 137 PGGVMPRMLITIMGTVKPNANRIVLDFRRG----NDVAFHFNPRFNENnrrVIVCNTKQDNNWGKEERQSAFPFESGKPF 212
Cdd:pfam00337 1 PGGLQPGSSLTIKGIVLPDAQRFSINLQTGvgpsDDIALHFNPRFDEN---VIVRNSRQNGQWGQEEREGGFPFQPGQPF 77
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 33859580 213 KIQVLVEADHFKVAVNDAHLLQYNHRMKNlREISQLGISGDITLTS 258
Cdd:pfam00337 78 ELTILVGDDHFKIYVNGQHFTTFKHRLPP-EDIDALQVRGDVKLTS 122
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
9-139 |
2.56e-08 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 54.22 E-value: 2.56e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859580 9 DALAGSGNPNPQGYPGAWGNQPGAGGYPGAAYPGAYPGQAPPGAYPGQAPPGAYPGQAPPSAYPGPTAPGAYPGPTAPGA 88
Cdd:PRK07764 619 AAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAP 698
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 33859580 89 YPGSTAPGAFPGQPGAPGAYPSAPG-GYPAAGPYGVPAGPLTVPYDLPLPGG 139
Cdd:PRK07764 699 AQPAPAPAATPPAGQADDPAAQPPQaAQGASAPSPAADDPVPLPPEPDDPPD 750
|
|
| gly_rich_SclB |
NF038329 |
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ... |
15-127 |
8.42e-05 |
|
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.
Pssm-ID: 468478 [Multi-domain] Cd Length: 440 Bit Score: 43.36 E-value: 8.42e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859580 15 GNPNPQGYPGAWGNQPGAG--------GYPGAAYPGAYPGQAPPGAYPGQAPPGAYPGQAPPSAYPGPTAPGAYPGPTAP 86
Cdd:NF038329 132 GEQGPRGDRGETGPAGPAGppgpqgerGEKGPAGPQGEAGPQGPAGKDGEAGAKGPAGEKGPQGPRGETGPAGEQGPAGP 211
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 33859580 87 GAYPGSTAPGAFPGQPGAPGAYPSAPGGYPAAGPYGVPAGP 127
Cdd:NF038329 212 AGPDGEAGPAGEDGPAGPAGDGQQGPDGDPGPTGEDGPQGP 252
|
|
| Glutenin_hmw |
pfam03157 |
High molecular weight glutenin subunit; Members of this family include high molecular weight ... |
27-112 |
2.03e-04 |
|
High molecular weight glutenin subunit; Members of this family include high molecular weight subunits of glutenin. This group of gluten proteins is thought to be largely responsible for the elastic properties of gluten, and hence, doughs. Indeed, glutenin high molecular weight subunits are classified as elastomeric proteins, because the glutenin network can withstand significant deformations without breaking, and return to the original conformation when the stress is removed. Elastomeric proteins differ considerably in amino acid sequence, but they are all polymers whose subunits consist of elastomeric domains, composed of repeated motifs, and non-elastic domains that mediate cross-linking between the subunits. The elastomeric domain motifs are all rich in glycine residues in addition to other hydrophobic residues. High molecular weight glutenin subunits have an extensive central elastomeric domain, flanked by two terminal non-elastic domains that form disulphide cross-links. The central elastomeric domain is characterized by the following three repeated motifs: PGQGQQ, GYYPTS[P/L]QQ, GQQ. It possesses overlapping beta-turns within and between the repeated motifs, and assumes a regular helical secondary structure with a diameter of approx. 1.9 nm and a pitch of approx. 1.5 nm.
Pssm-ID: 367362 [Multi-domain] Cd Length: 786 Bit Score: 42.63 E-value: 2.03e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859580 27 GNQPGAGGYPGAAYPGA--YPGQAPPGAYPGQAPPGAYPGQAPPSAYPGPTAPGAYPGPTAPGAYPGSTAPGAFPGQP-- 102
Cdd:pfam03157 440 GQQPGQGQQPGQEQPGQgqQPGQGQQGQQPGQPEQGQQPGQGQPGYYPTSPQQSGQGQQLGQWQQQGQGQPGYYPTSPlq 519
|
90
....*....|...
gi 33859580 103 ---GAPGAYPSAP 112
Cdd:pfam03157 520 pgqGQPGYYPTSP 532
|
|
| PBP1 |
COG5180 |
PAB1-binding protein, interacts with poly(A)-binding protein [RNA processing and modification]; ... |
12-143 |
2.80e-04 |
|
PAB1-binding protein, interacts with poly(A)-binding protein [RNA processing and modification];
Pssm-ID: 444064 [Multi-domain] Cd Length: 548 Bit Score: 41.97 E-value: 2.80e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859580 12 AGSGNPNPQGYPGAWGNQPGAGGYPGAAYPGAY----PGQAPPGAYPGQAPPGAYPGQAPPSAYPGPTAPGAYPGPTAPG 87
Cdd:COG5180 345 ASDAGQPPSAYPPAEEAVPGKPLEQGAPRPGSSggdgAPFQPPNGAPQPGLGRRGAPGPPMGAGDLVQAALDGGGRETAS 424
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*.
gi 33859580 88 AYPGSTAPGAFPGQPGAPGAYPSAPGGYPAAGPYGVPAGPLTVPYDLPLPGGVMPR 143
Cdd:COG5180 425 LGGAAGGAGQGPKADFVPGDAESVSGPAGLADQAGAAASTAMADFVAPVTDATPVD 480
|
|
| KREPA2 |
cd23959 |
Kinetoplastid RNA Editing Protein A2 (KREPA2); The KREPA2 (TbMP63) protein is a component of ... |
45-133 |
3.89e-04 |
|
Kinetoplastid RNA Editing Protein A2 (KREPA2); The KREPA2 (TbMP63) protein is a component of the parasitic protozoan's KREPA RNA editing catalytic complex (RECC). Kinetoplastid RNA editing (KRE) proteins occur as pairs or sets of related proteins in multiple complexes. KREPA complex is composed of six components (KREPA1-6), which share a conserved C-terminal region containing an oligonucleotide-binding (OB)-fold-like domain. KREPAs are responsible for the site-specific insertion and deletion of U nucleotides in the kinetoplastid mitochondria pre-messenger RNA. Apart from the conserved C-terminal OB-fold domain, KREPA1, KREPA2, and KREPA3 contain two conserved C2H2 zinc-finger domains. KREPA2 and kinetoplastid RNA editing ligase 1 (KREL1) are specific for ligation post-U-deletion and are paralogous to KREL2 and KREPA1 that are specific for ligation post-U-insertion. KREPA2, is critical for RECC stability and KREL1 integration into the complex.
Pssm-ID: 467780 [Multi-domain] Cd Length: 424 Bit Score: 41.39 E-value: 3.89e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859580 45 PGQAPPGAYPGQAPPGAYPGQAPPSAYPGPTAPGAYPGP---TAPGAYPGSTAPGAFPGQPGAPGayPSAPGGYPAAGPY 121
Cdd:cd23959 156 FGQHPPPAKPLPAAAAAQQSSASPGEVASPFASGTVSASpfaTATDTAPSSGAPDGFPAEASAPS--PFAAPASAASFPA 233
|
90
....*....|..
gi 33859580 122 GVPAGPLTVPYD 133
Cdd:cd23959 234 APVANGEAATPT 245
|
|
| SAV_2336_NTERM |
NF041121 |
SAV_2336 family N-terminal domain; This HMM describes an N-terminal domain shared by SAV_2336 ... |
36-162 |
6.38e-04 |
|
SAV_2336 family N-terminal domain; This HMM describes an N-terminal domain shared by SAV_2336 (BAC70047.1) whose C-terminal region suggests restriction enzyme activity (PMID: 18456708), and with other proteins with unrelated C-terminal regions. A member protein was also identified in a kanamycin biosynthetic gene cluster (PMID:16766657), while N-terminal regions of two other member proteins were named Trypco1 in a bioinformatic study (PMID:32101166) of predicted bacterial conflict systems.
Pssm-ID: 469044 [Multi-domain] Cd Length: 473 Bit Score: 40.76 E-value: 6.38e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859580 36 PGAAYPGAYPGQAPPGAypgQAPPGAYPGQAPPSAYPGPTAPGAYPGPTAPGAYPGSTAPGAFPgqpgAPGAYPSAPGgy 115
Cdd:NF041121 16 GRAAAPPSPEGPAPTAA---SQPATPPPPAAPPSPPGDPPEPPAPEPAPLPAPYPGSLAPPPPP----PPGPAGAAPG-- 86
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 33859580 116 pAAGPYGVPAGPltvpydlPLPGGV-MPRMLITIMGTVkPNANRIVLD 162
Cdd:NF041121 87 -AALPVRVPAPP-------ALPNPLeLARALRPLKRRV-PSPRRVELD 125
|
|
| PABP-1234 |
TIGR01628 |
polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins ... |
36-137 |
1.53e-03 |
|
polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins recognize the poly-A of mRNA and consists of four tandem RNA recognition domains at the N-terminus (rrm: pfam00076) followed by a PABP-specific domain (pfam00658) at the C-terminus. The protein is involved in the transport of mRNA's from the nucleus to the cytoplasm. There are four paralogs in Homo sapiens which are expressed in testis, platelets, broadly expressed and of unknown tissue range.
Pssm-ID: 130689 [Multi-domain] Cd Length: 562 Bit Score: 39.79 E-value: 1.53e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859580 36 PGAAYPGAYPGQAPPGAYPGQapPGAYPGQAPpsaYPGPTAPGAYPGPTAPGAYPGSTAPG----AFPGQPgAPGAYPSA 111
Cdd:TIGR01628 392 GGAMGQPPYYGQGPQQQFNGQ--PLGWPRMSM---MPTPMGPGGPLRPNGLAPMNAVRAPSrnaqNAAQKP-PMQPVMYP 465
|
90 100
....*....|....*....|....*.
gi 33859580 112 PGGYPAAGPYGVPAGPLTVPYDLPLP 137
Cdd:TIGR01628 466 PNYQSLPLSQDLPQPQSTASQGGQNK 491
|
|
| gly_rich_SclB |
NF038329 |
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ... |
15-106 |
5.97e-03 |
|
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.
Pssm-ID: 468478 [Multi-domain] Cd Length: 440 Bit Score: 37.58 E-value: 5.97e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859580 15 GNPNPQGYPGAWGnQPGAGGYPGAAYPGAYPGQAPPGAYPGQAPPGAYPGQAPPSAYPGPTAPgAYPGPTAPGAYPGSTA 94
Cdd:NF038329 168 GEAGPQGPAGKDG-EAGAKGPAGEKGPQGPRGETGPAGEQGPAGPAGPDGEAGPAGEDGPAGP-AGDGQQGPDGDPGPTG 245
|
90
....*....|..
gi 33859580 95 PGAFPGQPGAPG 106
Cdd:NF038329 246 EDGPQGPDGPAG 257
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| Gal-bind_lectin |
smart00908 |
Galactoside-binding lectin; Animal lectins display a wide variety of architectures. They are ... |
137-258 |
1.22e-54 |
|
Galactoside-binding lectin; Animal lectins display a wide variety of architectures. They are classified according to the carbohydrate-recognition domain (CRD) of which there are two main types, S-type and C-type. Galectins (previously S-lectins) bind exclusively beta-galactosides like lactose. They do not require metal ions for activity. Galectins are found predominantly, but not exclusively in mammals. Their function is unclear. They are developmentally regulated and may be involved in differentiation, cellular regulation and tissue construction.
Pssm-ID: 214904 Cd Length: 122 Bit Score: 172.01 E-value: 1.22e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859580 137 PGGVMPRMLITIMGTVKPNANRIVLDFRRG--NDVAFHFNPRFNENnrrVIVCNTKQDNNWGKEERQSAFPFESGKPFKI 214
Cdd:smart00908 1 PGGLSPGSSITIRGIVLPDAKRFSINLQCGpnADIALHFNPRFDEG---TIVRNSKQNGKWGKEERSGGFPFQPGQPFEL 77
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 33859580 215 QVLVEADHFKVAVNDAHLLQYNHRMKnLREISQLGISGDITLTS 258
Cdd:smart00908 78 EILVEEDEFKVAVNGQHFLEFPHRLP-LESIDTLEISGDVQLTS 120
|
|
| GLECT |
cd00070 |
Galectin/galactose-binding lectin. This domain exclusively binds beta-galactosides, such as ... |
131-258 |
7.17e-54 |
|
Galectin/galactose-binding lectin. This domain exclusively binds beta-galactosides, such as lactose, and does not require metal ions for activity. GLECT domains occur as homodimers or tandemly repeated domains. They are developmentally regulated and may be involved in differentiation, cell-cell interaction and cellular regulation.
Pssm-ID: 238025 Cd Length: 127 Bit Score: 170.51 E-value: 7.17e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859580 131 PYDLPLPGGVMPRMLITIMGTVKPNANRIVLDFRRGN-DVAFHFNPRFNENnrrVIVCNTKQDNNWGKEERQSAFPFESG 209
Cdd:cd00070 1 PYKLPLPGGLKPGSTLTVKGRVLPNAKRFSINLGTGSsDIALHFNPRFDEN---VIVRNSFLNGNWGPEERSGGFPFQPG 77
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 33859580 210 KPFKIQVLVEADHFKVAVNDAHLLQYNHRMKnLREISQLGISGDITLTS 258
Cdd:cd00070 78 QPFELTILVEEDKFQIFVNGQHFFSFPHRLP-LESIDYLSINGDVSLTS 125
|
|
| Gal-bind_lectin |
pfam00337 |
Galactoside-binding lectin; This family contains galactoside binding lectins. The family also ... |
137-258 |
1.03e-49 |
|
Galactoside-binding lectin; This family contains galactoside binding lectins. The family also includes enzymes such as human eosinophil lysophospholipase (EC:3.1.1.5).
Pssm-ID: 459768 Cd Length: 124 Bit Score: 159.73 E-value: 1.03e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859580 137 PGGVMPRMLITIMGTVKPNANRIVLDFRRG----NDVAFHFNPRFNENnrrVIVCNTKQDNNWGKEERQSAFPFESGKPF 212
Cdd:pfam00337 1 PGGLQPGSSLTIKGIVLPDAQRFSINLQTGvgpsDDIALHFNPRFDEN---VIVRNSRQNGQWGQEEREGGFPFQPGQPF 77
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 33859580 213 KIQVLVEADHFKVAVNDAHLLQYNHRMKNlREISQLGISGDITLTS 258
Cdd:pfam00337 78 ELTILVGDDHFKIYVNGQHFTTFKHRLPP-EDIDALQVRGDVKLTS 122
|
|
| GLECT |
smart00276 |
Galectin; Galectin - galactose-binding lectin |
132-260 |
1.97e-49 |
|
Galectin; Galectin - galactose-binding lectin
Pssm-ID: 214596 Cd Length: 128 Bit Score: 158.93 E-value: 1.97e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859580 132 YDLPLPGGVMPRMLITIMGTVKPNANRIVLDFRRGN-DVAFHFNPRFNENnrrVIVCNTKQDNNWGKEERQSAFPFESGK 210
Cdd:smart00276 1 FTLPIPGGLKPGQTLTVRGIVLPDAKRFSINLLTGGdDIALHFNPRFNEN---KIVCNSKLNGSWGSEEREGGFPFQPGQ 77
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 33859580 211 PFKIQVLVEADHFKVAVNDAHLLQYNHRMKNLrEISQLGISGDITLTSAN 260
Cdd:smart00276 78 PFDLTIIVQPDHFQIFVNGVHITTFPHRLPLE-SIDYLSINGDVQLTSVS 126
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
9-139 |
2.56e-08 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 54.22 E-value: 2.56e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859580 9 DALAGSGNPNPQGYPGAWGNQPGAGGYPGAAYPGAYPGQAPPGAYPGQAPPGAYPGQAPPSAYPGPTAPGAYPGPTAPGA 88
Cdd:PRK07764 619 AAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAP 698
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 33859580 89 YPGSTAPGAFPGQPGAPGAYPSAPG-GYPAAGPYGVPAGPLTVPYDLPLPGG 139
Cdd:PRK07764 699 AQPAPAPAATPPAGQADDPAAQPPQaAQGASAPSPAADDPVPLPPEPDDPPD 750
|
|
| PRK14959 |
PRK14959 |
DNA polymerase III subunits gamma and tau; Provisional |
6-125 |
1.12e-07 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184923 [Multi-domain] Cd Length: 624 Bit Score: 52.37 E-value: 1.12e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859580 6 SLNDALAGSGNPNPQGYPGawgnqPGAGGYPGAAYPGAypgQAPPGAYP--GQAPPGAYPGQAPPSAYPGPTAP--GAYP 81
Cdd:PRK14959 370 SLRPSGGGASAPSGSAAEG-----PASGGAATIPTPGT---QGPQGTAPaaGMTPSSAAPATPAPSAAPSPRVPwdDAPP 441
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 33859580 82 GPTAPG--AYPGSTAPGAFPGqPGAPGAYPSAPGGYPAAGPYGVPA 125
Cdd:PRK14959 442 APPRSGipPRPAPRMPEASPV-PGAPDSVASASDAPPTLGDPSDTA 486
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
10-127 |
1.49e-06 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 48.83 E-value: 1.49e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859580 10 ALAGSGNPNPQGY-PGAWGNQPGAGGYPGAAYPGAYPGQAPPGAYP-------GQAPPGAYPGQAPPSAYPGPTAPGAYP 81
Cdd:PRK07764 594 AAGGEGPPAPASSgPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEAsaapapgVAAPEHHPKHVAVPDASDGGDGWPAKA 673
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 33859580 82 GPTAPGAYPGSTAPGAFPGQPGAPGAYPSA-----PGGYPAAGPYGVPAGP 127
Cdd:PRK07764 674 GGAAPAAPPPAPAPAAPAAPAGAAPAQPAPapaatPPAGQADDPAAQPPQA 724
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
9-185 |
1.97e-06 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 48.44 E-value: 1.97e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859580 9 DALAGSGNPNPQGYPGAWGNQPGAGGYPGAAYPGAYPGQAPPGAYPGQAPPGAYPGQAP---PSAYPGPTAPGAYPGPTA 85
Cdd:PRK07764 379 ERLERRLGVAGGAGAPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPapaPPSPAGNAPAGGAPSPPP 458
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859580 86 PGAYPGSTAPGAFPGQPGAPGAYPSAPGGYPAAGPYGVPAGPLTVPYDLPLPG---------GVMPRMLITIMGTVKPNA 156
Cdd:PRK07764 459 AAAPSAQPAPAPAAAPEPTAAPAPAPPAAPAPAAAPAAPAAPAAPAGADDAATlrerwpeilAAVPKRSRKTWAILLPEA 538
|
170 180 190
....*....|....*....|....*....|....*.
gi 33859580 157 -------NRIVLDFRRGNDVAFHFNPRFNENNRRVI 185
Cdd:PRK07764 539 tvlgvrgDTLVLGFSTGGLARRFASPGNAEVLVTAL 574
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
10-142 |
3.88e-06 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 47.67 E-value: 3.88e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859580 10 ALAGSGNPNPQGYPGAWGNQPGAGGYPGAAYPGAYPGQAPPGAYPGQAPPGAYpGQAPPSAYPGPTAPGAYPGPTAPGAY 89
Cdd:PRK07764 642 APAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPA-GAAPAQPAPAPAATPPAGQADDPAAQ 720
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 33859580 90 PGSTAPGAFPGQPGAPGAYP--SAPGGYPAAGPYGVPAGPLTVPYDLPLPGGVMP 142
Cdd:PRK07764 721 PPQAAQGASAPSPAADDPVPlpPEPDDPPDPAGAPAQPPPPPAPAPAAAPAAAPP 775
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
31-137 |
5.17e-06 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 47.18 E-value: 5.17e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859580 31 GAGGYPGAAYPGAYP---GQAPPGAYPGQAPPGAYPGQAPPSAYPGPtAPGAYPGPTAPGAYPGSTAPGAFPGQPGAPGA 107
Cdd:PRK12323 371 GAGPATAAAAPVAQPapaAAAPAAAAPAPAAPPAAPAAAPAAAAAAR-AVAAAPARRSPAPEALAAARQASARGPGGAPA 449
|
90 100 110
....*....|....*....|....*....|
gi 33859580 108 YPSAPGGYPAAGPYGVPAGPLTVPYDLPLP 137
Cdd:PRK12323 450 PAPAPAAAPAAAARPAAAGPRPVAAAAAAA 479
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
9-120 |
5.73e-06 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 47.29 E-value: 5.73e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859580 9 DALAGSGNPNPQGYPGAWGNQPGAGGYPGAAYPGAYPGQAPPGAYPGQAPPGAYPGQAPPSAYPGPTAPGAYPGPTAPGA 88
Cdd:PRK07764 668 GWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPPEPDD 747
|
90 100 110
....*....|....*....|....*....|..
gi 33859580 89 YPGSTAPGAFPGQPGAPGAYPSAPGGYPAAGP 120
Cdd:PRK07764 748 PPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPP 779
|
|
| PHA03378 |
PHA03378 |
EBNA-3B; Provisional |
17-145 |
8.06e-06 |
|
EBNA-3B; Provisional
Pssm-ID: 223065 [Multi-domain] Cd Length: 991 Bit Score: 46.98 E-value: 8.06e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859580 17 PNPQGYPGAwgNQPGAGGYPGAAYPGAYPGQA-PPGAYPGQA-PPGAYPGQA-PPSAYPGPTAPgaypgptaPGAYPGST 93
Cdd:PHA03378 705 RPPAAPPGR--AQRPAAATGRARPPAAAPGRArPPAAAPGRArPPAAAPGRArPPAAAPGRARP--------PAAAPGAP 774
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 33859580 94 APGAFPGQPGAPGAYPSApGGYPAAGPYGVPAGPLTVPYDLPLPGGVMPRML 145
Cdd:PHA03378 775 TPQPPPQAPPAPQQRPRG-APTPQPPPQAGPTSMQLMPRAAPGQQGPTKQIL 825
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
12-127 |
8.07e-06 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 46.90 E-value: 8.07e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859580 12 AGSGNPNPQGYPGAWGNQPGAGGYPGAAYPGAYPGQAPPGAYPGQAPPGAyPGQAPPSAYPGPTAPGAYPGPTAPGAYPG 91
Cdd:PRK07764 586 AVVGPAPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAA-PAEASAAPAPGVAAPEHHPKHVAVPDASD 664
|
90 100 110
....*....|....*....|....*....|....*.
gi 33859580 92 STAPGAFPGQPGAPGAYPSAPGGYPAAGPYGVPAGP 127
Cdd:PRK07764 665 GGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQ 700
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
36-138 |
1.11e-05 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 46.41 E-value: 1.11e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859580 36 PGAAYPGAYPGQAPPGAYPGQAPPGAYPGQAPPSAYPGPTA-----------PGAYPGPT-APGAYPGSTAPGAFPGQPG 103
Cdd:PRK12323 392 PAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEAlaaarqasargPGGAPAPApAPAAAPAAAARPAAAGPRP 471
|
90 100 110
....*....|....*....|....*....|....*....
gi 33859580 104 APGAYPSAPG-GYPAAGPYGVPAGPL---TVPYDLPLPG 138
Cdd:PRK12323 472 VAAAAAAAPArAAPAAAPAPADDDPPpweELPPEFASPA 510
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
30-152 |
1.42e-05 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 45.86 E-value: 1.42e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859580 30 PGAGGY---PGAAYPGAYPGQAPPGAYP-GQAPPGAYPGQAPPSAYPGPTAPGAYPGPtAPGAYPGSTAPGAFPGQPGAP 105
Cdd:PRK14951 366 PAAAAEaaaPAEKKTPARPEAAAPAAAPvAQAAAAPAPAAAPAAAASAPAAPPAAAPP-APVAAPAAAAPAAAPAAAPAA 444
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 33859580 106 GAYPSAPGGYPAAGPYGVPAG-----PLTVPYDLPLPGGVMPRMLITIMGTV 152
Cdd:PRK14951 445 VALAPAPPAQAAPETVAIPVRvapepAVASAAPAPAAAPAAARLTPTEEGDV 496
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
32-139 |
1.54e-05 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 45.75 E-value: 1.54e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859580 32 AGGYPGAAYPGAYPGQAPPGAYPGQ---APPGAYPGQAPPSAYPGPTAPGAYPGPTAPGAYPGSTAPGAFP-------GQ 101
Cdd:PRK07764 588 VGPAPGAAGGEGPPAPASSGPPEEAarpAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAvpdasdgGD 667
|
90 100 110
....*....|....*....|....*....|....*...
gi 33859580 102 PGAPGAYPSAPGGYPAAGPYGVPAGPLTVPYDLPLPGG 139
Cdd:PRK07764 668 GWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAP 705
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
30-135 |
3.53e-05 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 44.84 E-value: 3.53e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859580 30 PGAGGYPGAAYPGAYPGQAPPgayPGQAPPGAYPGQAPPSAYPGPTAPGAYPGP--TAPGAYPGSTAPGAFPGQPGAPG- 106
Cdd:PRK07003 362 VTGGGAPGGGVPARVAGAVPA---PGARAAAAVGASAVPAVTAVTGAAGAALAPkaAAAAAATRAEAPPAAPAPPATADr 438
|
90 100
....*....|....*....|....*....
gi 33859580 107 AYPSAPGGYPAAGPYGVPAGPLTVPYDLP 135
Cdd:PRK07003 439 GDDAADGDAPVPAKANARASADSRCDERD 467
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
17-143 |
4.45e-05 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 44.48 E-value: 4.45e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859580 17 PNPQGYPGAWGNQPGAGGYPGAAYPG----AYPGQAPPGAYPGQAPPGAYPGQAPPSAYPGPTAPGAYPGPTAPGAYPGS 92
Cdd:PRK12323 404 AAPAAAPAAAAAARAVAAAPARRSPApealAAARQASARGPGGAPAPAPAPAAAPAAAARPAAAGPRPVAAAAAAAPARA 483
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 33859580 93 TAPGAFPGQPGAPGAYPSAPGGYPAAGPYGVPAGPL-TVPYDLPLPGGVMPR 143
Cdd:PRK12323 484 APAAAPAPADDDPPPWEELPPEFASPAPAQPDAAPAgWVAESIPDPATADPD 535
|
|
| dnaA |
PRK14086 |
chromosomal replication initiator protein DnaA; |
41-138 |
5.19e-05 |
|
chromosomal replication initiator protein DnaA;
Pssm-ID: 237605 [Multi-domain] Cd Length: 617 Bit Score: 44.05 E-value: 5.19e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859580 41 PGAYPGQAPPGAYPG-QAPPGAYPGQAPPSAYPGPTA----PGAYPGPTAPgaypgsTAPGAFPG--QPGAPGAYPSAPG 113
Cdd:PRK14086 90 PSAGEPAPPPPHARRtSEPELPRPGRRPYEGYGGPRAddrpPGLPRQDQLP------TARPAYPAyqQRPEPGAWPRAAD 163
|
90 100 110
....*....|....*....|....*....|....*
gi 33859580 114 ---------GYPAAGPYGVPAGPLTVP-YDLPLPG 138
Cdd:PRK14086 164 dygwqqqrlGFPPRAPYASPASYAPEQeRDREPYD 198
|
|
| gly_rich_SclB |
NF038329 |
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ... |
15-127 |
8.42e-05 |
|
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.
Pssm-ID: 468478 [Multi-domain] Cd Length: 440 Bit Score: 43.36 E-value: 8.42e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859580 15 GNPNPQGYPGAWGNQPGAG--------GYPGAAYPGAYPGQAPPGAYPGQAPPGAYPGQAPPSAYPGPTAPGAYPGPTAP 86
Cdd:NF038329 132 GEQGPRGDRGETGPAGPAGppgpqgerGEKGPAGPQGEAGPQGPAGKDGEAGAKGPAGEKGPQGPRGETGPAGEQGPAGP 211
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 33859580 87 GAYPGSTAPGAFPGQPGAPGAYPSAPGGYPAAGPYGVPAGP 127
Cdd:NF038329 212 AGPDGEAGPAGEDGPAGPAGDGQQGPDGDPGPTGEDGPQGP 252
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
48-143 |
8.65e-05 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 43.44 E-value: 8.65e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859580 48 APPGAYPGQAPPGAYPGQAPPSAYPGPTAPGAYPGPTAPGAYPGSTAPGAFPGQPGAPGAYPSAPGGYPAAGPYGVPAGP 127
Cdd:PRK07764 589 GPAPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDG 668
|
90
....*....|....*.
gi 33859580 128 LTVPYDLPLPGGVMPR 143
Cdd:PRK07764 669 WPAKAGGAAPAAPPPA 684
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
17-137 |
9.12e-05 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 43.77 E-value: 9.12e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859580 17 PNPQGYPGAWGNQ---PGAGGYPGAAYPGAYPGQAPPGAYPGQAPPGAYPGQAPPSAYPGPTAPGAYPGPTAPGAyPGST 93
Cdd:PHA03247 2706 PTPEPAPHALVSAtplPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPP-RRLT 2784
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 33859580 94 APGAFPGQPGAPGA-YPSAPGGYPAAGPYGVPAGPLTVPYDLPLP 137
Cdd:PHA03247 2785 RPAVASLSESRESLpSPWDPADPPAAVLAPAAALPPAASPAGPLP 2829
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
41-127 |
1.35e-04 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 43.00 E-value: 1.35e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859580 41 PGAYPGQAPPGAYPGQAPPGAYPGQAPP---SAYPGPTAP----GAYPGPTAPGAYPGSTAPGAFPGQPGAPGAyPSAPG 113
Cdd:PHA03247 2686 RAARPTVGSLTSLADPPPPPPTPEPAPHalvSATPLPPGPaaarQASPALPAAPAPPAVPAGPATPGGPARPAR-PPTTA 2764
|
90
....*....|....
gi 33859580 114 GYPAAGPYGVPAGP 127
Cdd:PHA03247 2765 GPPAPAPPAAPAAG 2778
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
49-136 |
1.40e-04 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 43.00 E-value: 1.40e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859580 49 PPGAYPGQAPPGAYPG-QAPPSAYPGPTAPGAYPGPTAPGAYPGSTAPGAFPGQPGAPGAYPSAPGGYPAAGPYGVPAGP 127
Cdd:PHA03247 2703 PPPPTPEPAPHALVSAtPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRR 2782
|
....*....
gi 33859580 128 LTVPYDLPL 136
Cdd:PHA03247 2783 LTRPAVASL 2791
|
|
| Glutenin_hmw |
pfam03157 |
High molecular weight glutenin subunit; Members of this family include high molecular weight ... |
27-112 |
2.03e-04 |
|
High molecular weight glutenin subunit; Members of this family include high molecular weight subunits of glutenin. This group of gluten proteins is thought to be largely responsible for the elastic properties of gluten, and hence, doughs. Indeed, glutenin high molecular weight subunits are classified as elastomeric proteins, because the glutenin network can withstand significant deformations without breaking, and return to the original conformation when the stress is removed. Elastomeric proteins differ considerably in amino acid sequence, but they are all polymers whose subunits consist of elastomeric domains, composed of repeated motifs, and non-elastic domains that mediate cross-linking between the subunits. The elastomeric domain motifs are all rich in glycine residues in addition to other hydrophobic residues. High molecular weight glutenin subunits have an extensive central elastomeric domain, flanked by two terminal non-elastic domains that form disulphide cross-links. The central elastomeric domain is characterized by the following three repeated motifs: PGQGQQ, GYYPTS[P/L]QQ, GQQ. It possesses overlapping beta-turns within and between the repeated motifs, and assumes a regular helical secondary structure with a diameter of approx. 1.9 nm and a pitch of approx. 1.5 nm.
Pssm-ID: 367362 [Multi-domain] Cd Length: 786 Bit Score: 42.63 E-value: 2.03e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859580 27 GNQPGAGGYPGAAYPGA--YPGQAPPGAYPGQAPPGAYPGQAPPSAYPGPTAPGAYPGPTAPGAYPGSTAPGAFPGQP-- 102
Cdd:pfam03157 440 GQQPGQGQQPGQEQPGQgqQPGQGQQGQQPGQPEQGQQPGQGQPGYYPTSPQQSGQGQQLGQWQQQGQGQPGYYPTSPlq 519
|
90
....*....|...
gi 33859580 103 ---GAPGAYPSAP 112
Cdd:pfam03157 520 pgqGQPGYYPTSP 532
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
10-112 |
2.32e-04 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 42.28 E-value: 2.32e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859580 10 ALAGSGNPNPQGYPGAWGNQPGAGGYPGA-------AYPGAYPGQAPPGAYPGQAPPGAYPGQAPPSAYPGPTAPGAYPG 82
Cdd:PRK07764 671 AKAGGAAPAAPPPAPAPAAPAAPAGAAPAqpapapaATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPPEPDDPPD 750
|
90 100 110
....*....|....*....|....*....|
gi 33859580 83 PTAPGAYPGSTAPGAFPGQPGAPGAYPSAP 112
Cdd:PRK07764 751 PAGAPAQPPPPPAPAPAAAPAAAPPPSPPS 780
|
|
| PBP1 |
COG5180 |
PAB1-binding protein, interacts with poly(A)-binding protein [RNA processing and modification]; ... |
12-143 |
2.80e-04 |
|
PAB1-binding protein, interacts with poly(A)-binding protein [RNA processing and modification];
Pssm-ID: 444064 [Multi-domain] Cd Length: 548 Bit Score: 41.97 E-value: 2.80e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859580 12 AGSGNPNPQGYPGAWGNQPGAGGYPGAAYPGAY----PGQAPPGAYPGQAPPGAYPGQAPPSAYPGPTAPGAYPGPTAPG 87
Cdd:COG5180 345 ASDAGQPPSAYPPAEEAVPGKPLEQGAPRPGSSggdgAPFQPPNGAPQPGLGRRGAPGPPMGAGDLVQAALDGGGRETAS 424
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*.
gi 33859580 88 AYPGSTAPGAFPGQPGAPGAYPSAPGGYPAAGPYGVPAGPLTVPYDLPLPGGVMPR 143
Cdd:COG5180 425 LGGAAGGAGQGPKADFVPGDAESVSGPAGLADQAGAAASTAMADFVAPVTDATPVD 480
|
|
| kgd |
PRK12270 |
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine ... |
27-104 |
3.44e-04 |
|
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit;
Pssm-ID: 237030 [Multi-domain] Cd Length: 1228 Bit Score: 41.80 E-value: 3.44e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 33859580 27 GNQPGAGGYPGAAYPGAYPGQAPPGAYPGQAPPGAYPGQAPPSAYPGPT-APGAYPGPTAPGAYPGSTAPGAFPGQPGA 104
Cdd:PRK12270 39 GSTAAPTAAAAAAAAAASAPAAAPAAKAPAAPAPAPPAAAAPAAPPKPAaAAAAAAAPAAPPAAAAAAAPAAAAVEDEV 117
|
|
| kgd |
PRK12270 |
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine ... |
54-138 |
3.47e-04 |
|
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit;
Pssm-ID: 237030 [Multi-domain] Cd Length: 1228 Bit Score: 41.80 E-value: 3.47e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859580 54 PGQAPPGAYPGQAPPSAYPGPTAPGAYPGPTAPGAYPGSTAPGAFPGQPGAPGAYPSAPGGYPAAGPYGVPAGPLTVPYD 133
Cdd:PRK12270 38 PGSTAAPTAAAAAAAAAASAPAAAPAAKAPAAPAPAPPAAAAPAAPPKPAAAAAAAAAPAAPPAAAAAAAPAAAAVEDEV 117
|
....*
gi 33859580 134 LPLPG 138
Cdd:PRK12270 118 TPLRG 122
|
|
| dnaA |
PRK14086 |
chromosomal replication initiator protein DnaA; |
17-143 |
3.54e-04 |
|
chromosomal replication initiator protein DnaA;
Pssm-ID: 237605 [Multi-domain] Cd Length: 617 Bit Score: 41.73 E-value: 3.54e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859580 17 PNPQGYPGAWGNQPGAGGYPGAAYPGAYPGQAPPGAYPGQA-PPGAYPGQAPPSaypgptAPGAYPGPTAPgaYPGSTAP 95
Cdd:PRK14086 100 PHARRTSEPELPRPGRRPYEGYGGPRADDRPPGLPRQDQLPtARPAYPAYQQRP------EPGAWPRAADD--YGWQQQR 171
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 33859580 96 GAFPgqPGAPgaYPSAPGGYPAAGPYGVPAGPLTVPYDLPLPGGVMPR 143
Cdd:PRK14086 172 LGFP--PRAP--YASPASYAPEQERDREPYDAGRPEYDQRRRDYDHPR 215
|
|
| KREPA2 |
cd23959 |
Kinetoplastid RNA Editing Protein A2 (KREPA2); The KREPA2 (TbMP63) protein is a component of ... |
45-133 |
3.89e-04 |
|
Kinetoplastid RNA Editing Protein A2 (KREPA2); The KREPA2 (TbMP63) protein is a component of the parasitic protozoan's KREPA RNA editing catalytic complex (RECC). Kinetoplastid RNA editing (KRE) proteins occur as pairs or sets of related proteins in multiple complexes. KREPA complex is composed of six components (KREPA1-6), which share a conserved C-terminal region containing an oligonucleotide-binding (OB)-fold-like domain. KREPAs are responsible for the site-specific insertion and deletion of U nucleotides in the kinetoplastid mitochondria pre-messenger RNA. Apart from the conserved C-terminal OB-fold domain, KREPA1, KREPA2, and KREPA3 contain two conserved C2H2 zinc-finger domains. KREPA2 and kinetoplastid RNA editing ligase 1 (KREL1) are specific for ligation post-U-deletion and are paralogous to KREL2 and KREPA1 that are specific for ligation post-U-insertion. KREPA2, is critical for RECC stability and KREL1 integration into the complex.
Pssm-ID: 467780 [Multi-domain] Cd Length: 424 Bit Score: 41.39 E-value: 3.89e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859580 45 PGQAPPGAYPGQAPPGAYPGQAPPSAYPGPTAPGAYPGP---TAPGAYPGSTAPGAFPGQPGAPGayPSAPGGYPAAGPY 121
Cdd:cd23959 156 FGQHPPPAKPLPAAAAAQQSSASPGEVASPFASGTVSASpfaTATDTAPSSGAPDGFPAEASAPS--PFAAPASAASFPA 233
|
90
....*....|..
gi 33859580 122 GVPAGPLTVPYD 133
Cdd:cd23959 234 APVANGEAATPT 245
|
|
| SAV_2336_NTERM |
NF041121 |
SAV_2336 family N-terminal domain; This HMM describes an N-terminal domain shared by SAV_2336 ... |
36-162 |
6.38e-04 |
|
SAV_2336 family N-terminal domain; This HMM describes an N-terminal domain shared by SAV_2336 (BAC70047.1) whose C-terminal region suggests restriction enzyme activity (PMID: 18456708), and with other proteins with unrelated C-terminal regions. A member protein was also identified in a kanamycin biosynthetic gene cluster (PMID:16766657), while N-terminal regions of two other member proteins were named Trypco1 in a bioinformatic study (PMID:32101166) of predicted bacterial conflict systems.
Pssm-ID: 469044 [Multi-domain] Cd Length: 473 Bit Score: 40.76 E-value: 6.38e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859580 36 PGAAYPGAYPGQAPPGAypgQAPPGAYPGQAPPSAYPGPTAPGAYPGPTAPGAYPGSTAPGAFPgqpgAPGAYPSAPGgy 115
Cdd:NF041121 16 GRAAAPPSPEGPAPTAA---SQPATPPPPAAPPSPPGDPPEPPAPEPAPLPAPYPGSLAPPPPP----PPGPAGAAPG-- 86
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 33859580 116 pAAGPYGVPAGPltvpydlPLPGGV-MPRMLITIMGTVkPNANRIVLD 162
Cdd:NF041121 87 -AALPVRVPAPP-------ALPNPLeLARALRPLKRRV-PSPRRVELD 125
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
32-143 |
7.12e-04 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 41.08 E-value: 7.12e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859580 32 AGGYPGAAYPGAYPGQA-----PPGAYPGQAPPGAYPGQAPPSAYPGPTAPGAYPGPtaPGAYPGSTAPGAFPGQPGAPG 106
Cdd:PHA03247 2548 AGDPPPPLPPAAPPAAPdrsvpPPRPAPRPSEPAVTSRARRPDAPPQSARPRAPVDD--RGDPRGPAPPSPLPPDTHAPD 2625
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 33859580 107 ayPSAPGGYPAA----GPYGVPAGPLTVPYDLPLPGGVMPR 143
Cdd:PHA03247 2626 --PPPPSPSPAAnepdPHPPPTVPPPERPRDDPAPGRVSRP 2664
|
|
| kgd |
PRK12270 |
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine ... |
36-131 |
7.52e-04 |
|
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit;
Pssm-ID: 237030 [Multi-domain] Cd Length: 1228 Bit Score: 40.64 E-value: 7.52e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859580 36 PGAAYPGAYPGQAPPGAYPGQAP-PGAYPGQAPPSAYPGPTAPGAYPGPTAPGAYPGSTAPGAFPGQPGAPGAYPSAPGG 114
Cdd:PRK12270 38 PGSTAAPTAAAAAAAAAASAPAAaPAAKAPAAPAPAPPAAAAPAAPPKPAAAAAAAAAPAAPPAAAAAAAPAAAAVEDEV 117
|
90 100
....*....|....*....|.
gi 33859580 115 YPAAGPYGVPA----GPLTVP 131
Cdd:PRK12270 118 TPLRGAAAAVAknmdASLEVP 138
|
|
| KREPA2 |
cd23959 |
Kinetoplastid RNA Editing Protein A2 (KREPA2); The KREPA2 (TbMP63) protein is a component of ... |
47-131 |
8.27e-04 |
|
Kinetoplastid RNA Editing Protein A2 (KREPA2); The KREPA2 (TbMP63) protein is a component of the parasitic protozoan's KREPA RNA editing catalytic complex (RECC). Kinetoplastid RNA editing (KRE) proteins occur as pairs or sets of related proteins in multiple complexes. KREPA complex is composed of six components (KREPA1-6), which share a conserved C-terminal region containing an oligonucleotide-binding (OB)-fold-like domain. KREPAs are responsible for the site-specific insertion and deletion of U nucleotides in the kinetoplastid mitochondria pre-messenger RNA. Apart from the conserved C-terminal OB-fold domain, KREPA1, KREPA2, and KREPA3 contain two conserved C2H2 zinc-finger domains. KREPA2 and kinetoplastid RNA editing ligase 1 (KREL1) are specific for ligation post-U-deletion and are paralogous to KREL2 and KREPA1 that are specific for ligation post-U-insertion. KREPA2, is critical for RECC stability and KREL1 integration into the complex.
Pssm-ID: 467780 [Multi-domain] Cd Length: 424 Bit Score: 40.24 E-value: 8.27e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859580 47 QAPPGAYPGQAPpgaYPGQAPPSAYPGPTAPGAYPGPTAPGAYPGSTAPGAFPGQPGAPGAYPSAPGGYP--------AA 118
Cdd:cd23959 143 QTAPVTPFGQLP---MFGQHPPPAKPLPAAAAAQQSSASPGEVASPFASGTVSASPFATATDTAPSSGAPdgfpaeasAP 219
|
90
....*....|...
gi 33859580 119 GPYGVPAGPLTVP 131
Cdd:cd23959 220 SPFAAPASAASFP 232
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
12-137 |
8.44e-04 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 40.60 E-value: 8.44e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859580 12 AGSGNPNPQGYPGAwgnQPGAGGYPGAAYPGAYPGQAPPGAYPGQAPPGA--YPGQAPPSAYPGPTAPGAYPGPTAPGAY 89
Cdd:PRK07003 362 VTGGGAPGGGVPAR---VAGAVPAPGARAAAAVGASAVPAVTAVTGAAGAalAPKAAAAAAATRAEAPPAAPAPPATADR 438
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 33859580 90 PGSTAPGAFPGQPGAPG-AYPSAPGGYPAAGPYGVPAGPLTVPYDLPLP 137
Cdd:PRK07003 439 GDDAADGDAPVPAKANArASADSRCDERDAQPPADSGSASAPASDAPPD 487
|
|
| PHA03378 |
PHA03378 |
EBNA-3B; Provisional |
10-103 |
8.84e-04 |
|
EBNA-3B; Provisional
Pssm-ID: 223065 [Multi-domain] Cd Length: 991 Bit Score: 40.44 E-value: 8.84e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859580 10 ALAGSGNPNPQGYPGAwgNQPGAGGYPGAAYPGAYPGQA-PPGAYPGQA-PPGAYPGQAPPSAYP--GPTA---PGAYPG 82
Cdd:PHA03378 718 AAATGRARPPAAAPGR--ARPPAAAPGRARPPAAAPGRArPPAAAPGRArPPAAAPGAPTPQPPPqaPPAPqqrPRGAPT 795
|
90 100
....*....|....*....|....
gi 33859580 83 PTAP---GAYPGSTAPGAFPGQPG 103
Cdd:PHA03378 796 PQPPpqaGPTSMQLMPRAAPGQQG 819
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
30-142 |
9.21e-04 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 40.69 E-value: 9.21e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859580 30 PGAGGYPGA-AYPGAYPGQAPPGAYPGQAPPGAypgqAPPSAYPGPTAPGAYPGPTAPGAYPGSTAPGAFPGQPGAPGAY 108
Cdd:PHA03247 2751 PGGPARPARpPTTAGPPAPAPPAAPAAGPPRRL----TRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAG 2826
|
90 100 110
....*....|....*....|....*....|....
gi 33859580 109 PSAPGGYPAAGPYGVPAGPltVPYDLPLPGGVMP 142
Cdd:PHA03247 2827 PLPPPTSAQPTAPPPPPGP--PPPSLPLGGSVAP 2858
|
|
| PRK14959 |
PRK14959 |
DNA polymerase III subunits gamma and tau; Provisional |
15-114 |
1.25e-03 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184923 [Multi-domain] Cd Length: 624 Bit Score: 40.05 E-value: 1.25e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859580 15 GNPNPQGYPGAWGNQPGAGGyPGAAYPGAYPGQAPPGaypGQAPPGayPGQAPPSAYPGPTAPGAYPGPTAPGAYpgSTA 94
Cdd:PRK14959 401 GTQGPQGTAPAAGMTPSSAA-PATPAPSAAPSPRVPW---DDAPPA--PPRSGIPPRPAPRMPEASPVPGAPDSV--ASA 472
|
90 100
....*....|....*....|
gi 33859580 95 PGAFPGQPGAPGAYPSAPGG 114
Cdd:PRK14959 473 SDAPPTLGDPSDTAEHTPSG 492
|
|
| PRK14965 |
PRK14965 |
DNA polymerase III subunits gamma and tau; Provisional |
30-134 |
1.26e-03 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237871 [Multi-domain] Cd Length: 576 Bit Score: 39.72 E-value: 1.26e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859580 30 PGAGGYPGAAYPGAYPGQAPP-GAYPGQAPPGAYPGQAPPSAYPGPTAPGAYPGPTAPGAYPGSTAPGAfpgqpgaPGAY 108
Cdd:PRK14965 382 PAPPSAAWGAPTPAAPAAPPPaAAPPVPPAAPARPAAARPAPAPAPPAAAAPPARSADPAAAASAGDRW-------RAFV 454
|
90 100
....*....|....*....|....*.
gi 33859580 109 PSAPGGYPAAGPYGVPAGPLTVPYDL 134
Cdd:PRK14965 455 AFVKGKKPALGASLEQGSPLGVSAGL 480
|
|
| PHA03378 |
PHA03378 |
EBNA-3B; Provisional |
23-131 |
1.40e-03 |
|
EBNA-3B; Provisional
Pssm-ID: 223065 [Multi-domain] Cd Length: 991 Bit Score: 40.05 E-value: 1.40e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859580 23 PGAWGNQPGAGGYPGAAYPGAYPGQAPPgayPGQAPPGAYPGQAPPSAYPGP---TAPGAYPGPTAPGAYPGSTAPGAFP 99
Cdd:PHA03378 669 IGHIPYQPSPTGANTMLPIQWAPGTMQP---PPRAPTPMRPPAAPPGRAQRPaaaTGRARPPAAAPGRARPPAAAPGRAR 745
|
90 100 110
....*....|....*....|....*....|...
gi 33859580 100 GQPGAPG-AYPSAPGGYPAAGPYGVPAGPLTVP 131
Cdd:PHA03378 746 PPAAAPGrARPPAAAPGRARPPAAAPGAPTPQP 778
|
|
| PABP-1234 |
TIGR01628 |
polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins ... |
36-137 |
1.53e-03 |
|
polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins recognize the poly-A of mRNA and consists of four tandem RNA recognition domains at the N-terminus (rrm: pfam00076) followed by a PABP-specific domain (pfam00658) at the C-terminus. The protein is involved in the transport of mRNA's from the nucleus to the cytoplasm. There are four paralogs in Homo sapiens which are expressed in testis, platelets, broadly expressed and of unknown tissue range.
Pssm-ID: 130689 [Multi-domain] Cd Length: 562 Bit Score: 39.79 E-value: 1.53e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859580 36 PGAAYPGAYPGQAPPGAYPGQapPGAYPGQAPpsaYPGPTAPGAYPGPTAPGAYPGSTAPG----AFPGQPgAPGAYPSA 111
Cdd:TIGR01628 392 GGAMGQPPYYGQGPQQQFNGQ--PLGWPRMSM---MPTPMGPGGPLRPNGLAPMNAVRAPSrnaqNAAQKP-PMQPVMYP 465
|
90 100
....*....|....*....|....*.
gi 33859580 112 PGGYPAAGPYGVPAGPLTVPYDLPLP 137
Cdd:TIGR01628 466 PNYQSLPLSQDLPQPQSTASQGGQNK 491
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
10-128 |
1.58e-03 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 39.92 E-value: 1.58e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859580 10 ALAGSGNPNPQGYPgawgnqPGAGGYPGAAYPGAYPGQAPPGAYPGQAPPGAYPGQAPPSAYPGPTAPGAYPGPTAPGAY 89
Cdd:PHA03247 2747 GPATPGGPARPARP------PTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPP 2820
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 33859580 90 PGSTAPGAFPGQPGAPGAYPSAPGGYPAAGPYG---VPAGPL 128
Cdd:PHA03247 2821 AASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGgsvAPGGDV 2862
|
|
| Glutenin_hmw |
pfam03157 |
High molecular weight glutenin subunit; Members of this family include high molecular weight ... |
13-112 |
1.79e-03 |
|
High molecular weight glutenin subunit; Members of this family include high molecular weight subunits of glutenin. This group of gluten proteins is thought to be largely responsible for the elastic properties of gluten, and hence, doughs. Indeed, glutenin high molecular weight subunits are classified as elastomeric proteins, because the glutenin network can withstand significant deformations without breaking, and return to the original conformation when the stress is removed. Elastomeric proteins differ considerably in amino acid sequence, but they are all polymers whose subunits consist of elastomeric domains, composed of repeated motifs, and non-elastic domains that mediate cross-linking between the subunits. The elastomeric domain motifs are all rich in glycine residues in addition to other hydrophobic residues. High molecular weight glutenin subunits have an extensive central elastomeric domain, flanked by two terminal non-elastic domains that form disulphide cross-links. The central elastomeric domain is characterized by the following three repeated motifs: PGQGQQ, GYYPTS[P/L]QQ, GQQ. It possesses overlapping beta-turns within and between the repeated motifs, and assumes a regular helical secondary structure with a diameter of approx. 1.9 nm and a pitch of approx. 1.5 nm.
Pssm-ID: 367362 [Multi-domain] Cd Length: 786 Bit Score: 39.55 E-value: 1.79e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859580 13 GSGNPNPQGYPGAWGNQPGAGGYPGAAYPGAYPGQAPPGAYP------GQAPPGAYPG---QAPPSAYPGPTAPGAYPGP 83
Cdd:pfam03157 315 GQEQQDQQPGQGRQGQQPGQGQQGQQPAQGQQPGQGQPGYYPtspqqpGQGQPGYYPTsqqQPQQGQQPEQGQQGQQQGQ 394
|
90 100
....*....|....*....|....*....
gi 33859580 84 TAPGAYPGStapGAFPGQpGAPGAYPSAP 112
Cdd:pfam03157 395 GQQGQQPGQ---GQQPGQ-GQPGYYPTSP 419
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
36-144 |
2.03e-03 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 39.37 E-value: 2.03e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859580 36 PGAAYPGAYPGQAPPGAYPGQAPPGAYPGQAPPSAYPGPTAPGAYPGPTApgayPGSTAPGAFPGQPGAPGAYPSAPGGY 115
Cdd:pfam03154 263 PQPLPQPSLHGQMPPMPHSLQTGPSHMQHPVPPQPFPLTPQSSQSQVPPG----PSPAAPGQSQQRIHTPPSQSQLQSQQ 338
|
90 100
....*....|....*....|....*....
gi 33859580 116 PAAgPYGVPAGPLTVPYDLPLPGGVMPRM 144
Cdd:pfam03154 339 PPR-EQPLPPAPLSMPHIKPPPTTPIPQL 366
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
23-143 |
2.08e-03 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 39.54 E-value: 2.08e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859580 23 PGAWGNQPGAGGYPGAAYPGAYPGQAPPGAYPGQAPPGAYPGQAPPSAyPGPTAPGAYPGPTAPGAYP-GSTAPG---AF 98
Cdd:PHA03247 2786 PAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTS-AQPTAPPPPPGPPPPSLPLgGSVAPGgdvRR 2864
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 33859580 99 PGQPGAPGAYPSAPGGYPAAGPYGVPAGPLTVPYDLPLPGGVMPR 143
Cdd:PHA03247 2865 RPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPP 2909
|
|
| PRK14965 |
PRK14965 |
DNA polymerase III subunits gamma and tau; Provisional |
37-118 |
2.10e-03 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237871 [Multi-domain] Cd Length: 576 Bit Score: 39.34 E-value: 2.10e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859580 37 GAAYPGAYPGQAPPGAYPGQAPPGAYPGQAPPSAYPGPTAPGAyPGPTAPGAyPGSTAPGAfpgqpgAPGAYPSAPGGYP 116
Cdd:PRK14965 380 GAPAPPSAAWGAPTPAAPAAPPPAAAPPVPPAAPARPAAARPA-PAPAPPAA-AAPPARSA------DPAAAASAGDRWR 451
|
..
gi 33859580 117 AA 118
Cdd:PRK14965 452 AF 453
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
12-131 |
2.30e-03 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 39.15 E-value: 2.30e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859580 12 AGSGNPNPQGYPGAWGNQPGAGGYPGAAYP---GAYPGQAPPGAYPGQAP--PGAYPGQAPPSAYPGPTAPGAYPGPTAP 86
Cdd:PHA03247 2634 AANEPDPHPPPTVPPPERPRDDPAPGRVSRprrARRLGRAAQASSPPQRPrrRAARPTVGSLTSLADPPPPPPTPEPAPH 2713
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 33859580 87 GAYPGSTAPGAFPGQPGAPGAYPSAPGGYPAAGPYGVPAGPLTVP 131
Cdd:PHA03247 2714 ALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPA 2758
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
10-128 |
2.38e-03 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 39.09 E-value: 2.38e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859580 10 ALAGSGNPNPQGYPGAWGNQPGAGGYPGAAYPGAYPGQAPPGAYPGQAPPGAYPGQAPPSAYPGP----TAPGAYPGP-- 83
Cdd:PRK12323 432 ALAAARQASARGPGGAPAPAPAPAAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDDPppweELPPEFASPap 511
|
90 100 110 120
....*....|....*....|....*....|....*....|....*..
gi 33859580 84 --TAPGAYPGSTAPGAFPGQPGAPGAYPSAPGGyPAAGPYGVPAGPL 128
Cdd:PRK12323 512 aqPDAAPAGWVAESIPDPATADPDDAFETLAPA-PAAAPAPRAAAAT 557
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
13-127 |
3.53e-03 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 38.54 E-value: 3.53e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859580 13 GSGNPNPQGYPGAWGNQPGAGGYPGAAYPGAYPGQAPPGAYPGQAPPGAYPGQAPPSAYPGPTAPGAYPGPTAPGAYPGS 92
Cdd:PRK14951 367 AAAAEAAAPAEKKTPARPEAAAPAAAPVAQAAAAPAPAAAPAAAASAPAAPPAAAPPAPVAAPAAAAPAAAPAAAPAAVA 446
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 33859580 93 TAP---------GAFPGQPGAPGAYPSAPGGYPAAGPYGVPAGP 127
Cdd:PRK14951 447 LAPappaqaapeTVAIPVRVAPEPAVASAAPAPAAAPAAARLTP 490
|
|
| PHA02682 |
PHA02682 |
ORF080 virion core protein; Provisional |
46-135 |
3.58e-03 |
|
ORF080 virion core protein; Provisional
Pssm-ID: 177464 [Multi-domain] Cd Length: 280 Bit Score: 37.92 E-value: 3.58e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859580 46 GQAPPGAYPG-QAPPGAYPGQAPPSAYPGPTAPGayPGPTAPGAYPGSTAPGAFPGQPGAPG-AYPSAPGGYPaagpygv 123
Cdd:PHA02682 78 GQSPLAPSPAcAAPAPACPACAPAAPAPAVTCPA--PAPACPPATAPTCPPPAVCPAPARPApACPPSTRQCP------- 148
|
90
....*....|..
gi 33859580 124 PAGPLTVPYDLP 135
Cdd:PHA02682 149 PAPPLPTPKPAP 160
|
|
| PRK12373 |
PRK12373 |
NADH-quinone oxidoreductase subunit E; |
41-144 |
4.24e-03 |
|
NADH-quinone oxidoreductase subunit E;
Pssm-ID: 237082 [Multi-domain] Cd Length: 400 Bit Score: 38.24 E-value: 4.24e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859580 41 PGAYPGQAPPGAYPGQAPPGAYPGQAPPSAYPGPTAPGAYPGPTAPGAYPGSTAPGAFPGQP--GAPGAYPSAPGGYPAA 118
Cdd:PRK12373 232 APWQGDAAPVPPSEAARPKSADAETNAALKTPATAPKAAAKNAKAPEAQPVSGTAAAEPAPKeaAKAAAAAAKPALEDKP 311
|
90 100
....*....|....*....|....*...
gi 33859580 119 GPYGV--PAGpltvPYDLPLPGGVMPRM 144
Cdd:PRK12373 312 RPLGIarPGG----ADDLKLISGVGPKI 335
|
|
| kgd |
PRK12270 |
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine ... |
9-93 |
4.37e-03 |
|
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit;
Pssm-ID: 237030 [Multi-domain] Cd Length: 1228 Bit Score: 38.33 E-value: 4.37e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859580 9 DALAGSGNPNPQGYPGAWGNQPGAGGYPgAAYPGAYPGQAPPGAYPGQAPPGAYPGQAPPSAYPGPTAPGAYPGPTAPGA 88
Cdd:PRK12270 35 DYGPGSTAAPTAAAAAAAAAASAPAAAP-AAKAPAAPAPAPPAAAAPAAPPKPAAAAAAAAAPAAPPAAAAAAAPAAAAV 113
|
....*
gi 33859580 89 YPGST 93
Cdd:PRK12270 114 EDEVT 118
|
|
| gly_rich_SclB |
NF038329 |
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ... |
15-106 |
5.97e-03 |
|
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.
Pssm-ID: 468478 [Multi-domain] Cd Length: 440 Bit Score: 37.58 E-value: 5.97e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859580 15 GNPNPQGYPGAWGnQPGAGGYPGAAYPGAYPGQAPPGAYPGQAPPGAYPGQAPPSAYPGPTAPgAYPGPTAPGAYPGSTA 94
Cdd:NF038329 168 GEAGPQGPAGKDG-EAGAKGPAGEKGPQGPRGETGPAGEQGPAGPAGPDGEAGPAGEDGPAGP-AGDGQQGPDGDPGPTG 245
|
90
....*....|..
gi 33859580 95 PGAFPGQPGAPG 106
Cdd:NF038329 246 EDGPQGPDGPAG 257
|
|
| PHA02682 |
PHA02682 |
ORF080 virion core protein; Provisional |
27-131 |
6.99e-03 |
|
ORF080 virion core protein; Provisional
Pssm-ID: 177464 [Multi-domain] Cd Length: 280 Bit Score: 37.15 E-value: 6.99e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859580 27 GNQPGAGGYPGAAYPGAYPGQAPPGAYPGQAPPGAYPGqAPPSAYPGPTAPGAYPGPTAPG-AYPGST--APGA--FPGQ 101
Cdd:PHA02682 78 GQSPLAPSPACAAPAPACPACAPAAPAPAVTCPAPAPA-CPPATAPTCPPPAVCPAPARPApACPPSTrqCPPAppLPTP 156
|
90 100 110
....*....|....*....|....*....|....*.
gi 33859580 102 PGAPGAYPS------APGGYPAAGPYGVPAGPLTVP 131
Cdd:PHA02682 157 KPAPAAKPIflhnqlPPPDYPAASCPTIETAPAASP 192
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
23-119 |
7.82e-03 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 37.55 E-value: 7.82e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859580 23 PGAWGNQPGAGGYPGAAYPGAYPGQAPPGAYPGQAPPGAYPGQAPPSAYPGPTAPGAYPGPTAPGAYPGSTAPGAFPGQP 102
Cdd:PRK12323 467 AGPRPVAAAAAAAPARAAPAAAPAPADDDPPPWEELPPEFASPAPAQPDAAPAGWVAESIPDPATADPDDAFETLAPAPA 546
|
90
....*....|....*..
gi 33859580 103 GAPGAYPSAPGGYPAAG 119
Cdd:PRK12323 547 AAPAPRAAAATEPVVAP 563
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
6-129 |
9.52e-03 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 37.23 E-value: 9.52e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 33859580 6 SLNDALAGSGNPNPQGYPGAWGNQPGAGGYPGAAYPGAYPGQAP----PGAYPGQAPPGAYPGQAPPSAYPGPTAPGAYP 81
Cdd:PHA03247 364 SLEDLSAGRHHPKRASLPTRKRRSARHAATPFARGPGGDDQTRPaapvPASVPTPAPTPVPASAPPPPATPLPSAEPGSD 443
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 33859580 82 GPTAPGAYPGSTAPGAFPGQPGAPGAYPSAPGGYPAAGPYGVPAGPLT 129
Cdd:PHA03247 444 DGPAPPPERQPPAPATEPAPDDPDDATRKALDALRERRPPEPPGADLA 491
|
|
| |
