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Conserved domains on  [gi|121247390|ref|NP_033307|]
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zinc finger protein 143 isoform 2 [Mus musculus]

Protein Classification

C2H2-type zinc finger protein( domain architecture ID 11472214)

Cys2His2 (C2H2)-type zinc finger protein may be involved in transcriptional regulation

CATH:  3.30.160.60
Gene Ontology:  GO:0008270|GO:0003677
PubMed:  11361095|22803940
SCOP:  4003583

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
250-423 1.09e-13

FOG: Zn-finger [General function prediction only];


:

Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 73.58  E-value: 1.09e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 121247390 250 AHHLKVHERSHTGdRPYQCEHSGCGKAFATGYGLKSHFRT--HTGE--KPYRCSEDNCTKSFKTSGDLQKHIRTHTGERP 325
Cdd:COG5048  273 SSPNESDSSSEKG-FSLPIKSKQCNISFSRSSPLTRHLRSvnHSGEslKPFSCPYSLCGKLFSRNDALKRHILLHTSISP 351

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 121247390 326 FKCPIEGCGRSFTTSNIRK-----VHIRTHTGERPYYCTEPGCGRAFASATNYKNHVRIHTGEKPYVCTVPGCDKRFTEY 400
Cdd:COG5048  352 AKEKLLNSSSKFSPLLNNEppqslQQYKDLKNDKKSETLSNSCIRNFKRDSNLSLHIITHLSFRPYNCKNPPCSKSFNRH 431

                        170       180
                 ....*....|....*....|...
gi 121247390 401 SSLYKHHVVHTHSKPYNCNHCGK 423
Cdd:COG5048  432 YNLIPHKKIHTNHAPLLCSILKS 454
SFP1 super family cl25788
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 206-291 1.04e-04

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


The actual alignment was detected with superfamily member COG5189:

Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 45.09  E-value: 1.04e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 121247390 206 ENEQEKKMQIVLQGHATRVTPKSQQ--SGEKAFRCKYDGCGKLYTTAHHLKVH---------------ERSHTG----DR 264
Cdd:COG5189  318 CTNSSSNGKLAHGGERNIDTPSRMLkvKDGKPYKCPVEGCNKKYKNQNGLKYHmlhghqnqklhenpsPEKMNIfsakDK 397

                         90       100
                 ....*....|....*....|....*..
gi 121247390 265 PYQCEHsgCGKAFATGYGLKSHfRTHT 291
Cdd:COG5189  398 PYRCEV--CDKRYKNLNGLKYH-RKHS 421
 
Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
250-423 1.09e-13

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 73.58  E-value: 1.09e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 121247390 250 AHHLKVHERSHTGdRPYQCEHSGCGKAFATGYGLKSHFRT--HTGE--KPYRCSEDNCTKSFKTSGDLQKHIRTHTGERP 325
Cdd:COG5048  273 SSPNESDSSSEKG-FSLPIKSKQCNISFSRSSPLTRHLRSvnHSGEslKPFSCPYSLCGKLFSRNDALKRHILLHTSISP 351

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 121247390 326 FKCPIEGCGRSFTTSNIRK-----VHIRTHTGERPYYCTEPGCGRAFASATNYKNHVRIHTGEKPYVCTVPGCDKRFTEY 400
Cdd:COG5048  352 AKEKLLNSSSKFSPLLNNEppqslQQYKDLKNDKKSETLSNSCIRNFKRDSNLSLHIITHLSFRPYNCKNPPCSKSFNRH 431

                        170       180
                 ....*....|....*....|...
gi 121247390 401 SSLYKHHVVHTHSKPYNCNHCGK 423
Cdd:COG5048  432 YNLIPHKKIHTNHAPLLCSILKS 454
zf-H2C2_2 pfam13465
Zinc-finger double domain;
283-309 2.38e-05

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 41.20  E-value: 2.38e-05
                          10        20
                  ....*....|....*....|....*..
gi 121247390  283 LKSHFRTHTGEKPYRCSEdnCTKSFKT 309
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPE--CGKSFKS 26
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 206-291 1.04e-04

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 45.09  E-value: 1.04e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 121247390 206 ENEQEKKMQIVLQGHATRVTPKSQQ--SGEKAFRCKYDGCGKLYTTAHHLKVH---------------ERSHTG----DR 264
Cdd:COG5189  318 CTNSSSNGKLAHGGERNIDTPSRMLkvKDGKPYKCPVEGCNKKYKNQNGLKYHmlhghqnqklhenpsPEKMNIfsakDK 397

                         90       100
                 ....*....|....*....|....*..
gi 121247390 265 PYQCEHsgCGKAFATGYGLKSHfRTHT 291
Cdd:COG5189  398 PYRCEV--CDKRYKNLNGLKYH-RKHS 421
 
Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
250-423 1.09e-13

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 73.58  E-value: 1.09e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 121247390 250 AHHLKVHERSHTGdRPYQCEHSGCGKAFATGYGLKSHFRT--HTGE--KPYRCSEDNCTKSFKTSGDLQKHIRTHTGERP 325
Cdd:COG5048  273 SSPNESDSSSEKG-FSLPIKSKQCNISFSRSSPLTRHLRSvnHSGEslKPFSCPYSLCGKLFSRNDALKRHILLHTSISP 351

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 121247390 326 FKCPIEGCGRSFTTSNIRK-----VHIRTHTGERPYYCTEPGCGRAFASATNYKNHVRIHTGEKPYVCTVPGCDKRFTEY 400
Cdd:COG5048  352 AKEKLLNSSSKFSPLLNNEppqslQQYKDLKNDKKSETLSNSCIRNFKRDSNLSLHIITHLSFRPYNCKNPPCSKSFNRH 431

                        170       180
                 ....*....|....*....|...
gi 121247390 401 SSLYKHHVVHTHSKPYNCNHCGK 423
Cdd:COG5048  432 YNLIPHKKIHTNHAPLLCSILKS 454
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
354-429 1.59e-08

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 57.40  E-value: 1.59e-08
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 121247390 354 RPYYCtePGCGRAFASATNYKNHVRIHTGEKPYVCTVPGCDKRFTEYSSLYKHHVVHTHSKPYNCNHCGKTYKQIS 429
Cdd:COG5048   32 RPDSC--PNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDKSFSRPLELSRHLRTHHNNPSDLNSKSLPLSNSKA 105
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 382-439 8.14e-08

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 55.11  E-value: 8.14e-08
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 121247390 382 GEKPYVCTVPGCDKRFTEYSSLyKHHVVHTH--------------------SKPYNCNHCGKTYKQISTLAMHKRTAH 439
Cdd:COG5189  346 DGKPYKCPVEGCNKKYKNQNGL-KYHMLHGHqnqklhenpspekmnifsakDKPYRCEVCDKRYKNLNGLKYHRKHSH 422
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 248-412 8.73e-08

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 54.72  E-value: 8.73e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 121247390 248 TTAHHLKVHERSHTGDrpYQCEHSGCGKA-----FATGYGLKSHFRTHTGEKPYRCSEDNCTKSFKTSGDLQKHIrthtG 322
Cdd:COG5189  273 SQGSAELFEESSLGFD--YEFIHKSVGNKeirggISTGEMIDVRKLPCTNSSSNGKLAHGGERNIDTPSRMLKVK----D 346

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 121247390 323 ERPFKCPIEGCGRSFTTSNIRKVH-IRTHTGERPYYCTEPGCGRAFASAtnyknhvrihtgEKPYVCTVpgCDKRFTEYS 401
Cdd:COG5189  347 GKPYKCPVEGCNKKYKNQNGLKYHmLHGHQNQKLHENPSPEKMNIFSAK------------DKPYRCEV--CDKRYKNLN 412

                        170
                 ....*....|.
gi 121247390 402 SLyKHHVVHTH 412
Cdd:COG5189  413 GL-KYHRKHSH 422
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
263-341 1.32e-06

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 51.24  E-value: 1.32e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 121247390 263 DRPYQCEhsGCGKAFATGYGLKSHFRTHTGEKPYRCSEDNCTKSFKTSGDLQKHIRTHTGERPFKCPIEGCGRSFTTSN 341
Cdd:COG5048   31 PRPDSCP--NCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDKSFSRPLELSRHLRTHHNNPSDLNSKSLPLSNSKASS 107
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
231-407 1.02e-05

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 48.54  E-value: 1.02e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 121247390 231 SGEKAFRCKYDGCGKLYTTAHHLKVHERSHTGDRPYQCEHSGCGKafatgyglkshfrTHTGEKPYrcsednctksfKTS 310
Cdd:COG5048  317 ESLKPFSCPYSLCGKLFSRNDALKRHILLHTSISPAKEKLLNSSS-------------KFSPLLNN-----------EPP 372

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 121247390 311 GDLQKHIRTHTgERPFKCPIEGCGRSFTTSNIRKVHIRTHTGERPYYCTEPGCGRAFASATNYKNHVRIHTGEKPYVCtv 390
Cdd:COG5048  373 QSLQQYKDLKN-DKKSETLSNSCIRNFKRDSNLSLHIITHLSFRPYNCKNPPCSKSFNRHYNLIPHKKIHTNHAPLLC-- 449

                        170
                 ....*....|....*..
gi 121247390 391 pgCDKRFTEYSSLYKHH 407
Cdd:COG5048  450 --SILKSFRRDLDLSNH 464
zf-H2C2_2 pfam13465
Zinc-finger double domain;
283-309 2.38e-05

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 41.20  E-value: 2.38e-05
                          10        20
                  ....*....|....*....|....*..
gi 121247390  283 LKSHFRTHTGEKPYRCSEdnCTKSFKT 309
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPE--CGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
312-339 2.57e-05

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 41.20  E-value: 2.57e-05
                          10        20
                  ....*....|....*....|....*...
gi 121247390  312 DLQKHIRTHTGERPFKCPIegCGRSFTT 339
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPE--CGKSFKS 26
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
358-441 2.88e-05

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 47.00  E-value: 2.88e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 121247390 358 CTEPGCGRAFASATNYKNHVR--IHTGE--KPYVCTVPGCDKRFTEYSSLYKHHVVHTHSKPYNC--NHCGKTYKQIST- 430
Cdd:COG5048  290 IKSKQCNISFSRSSPLTRHLRsvNHSGEslKPFSCPYSLCGKLFSRNDALKRHILLHTSISPAKEklLNSSSKFSPLLNn 369

                         90
                 ....*....|....*
gi 121247390 431 ----LAMHKRTAHND 441
Cdd:COG5048  370 eppqSLQQYKDLKND 384
zf-C2H2_8 pfam15909
C2H2-type zinc ribbon; This family carries three zinc-fingers in tandem.
 268-355 6.15e-05

C2H2-type zinc ribbon; This family carries three zinc-fingers in tandem.


Pssm-ID: 464935 [Multi-domain]  Cd Length: 98  Bit Score: 42.41  E-value: 6.15e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 121247390  268 CEHSGCGKAFATGYGLKSHFRTHTGE------KPYRCSEDNCTKSFKTSGDLQKHIRTH-TGERPFKCpiEGCGRSFTT- 339
Cdd:pfam15909   2 CSSPGCCLSFPSVRDLAQHLRTHCPPtqslegKLFRCSALSCTETFPSMQELVAHSKLHyKPNRYFKC--ENCLLRFRTh 79

                          90
                  ....*....|....*..
gi 121247390  340 -SNIRKVHIRTHTGERP 355
Cdd:pfam15909  80 rSLFKHLHVCAEHAQSP 96
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 206-291 1.04e-04

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 45.09  E-value: 1.04e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 121247390 206 ENEQEKKMQIVLQGHATRVTPKSQQ--SGEKAFRCKYDGCGKLYTTAHHLKVH---------------ERSHTG----DR 264
Cdd:COG5189  318 CTNSSSNGKLAHGGERNIDTPSRMLkvKDGKPYKCPVEGCNKKYKNQNGLKYHmlhghqnqklhenpsPEKMNIfsakDK 397

                         90       100
                 ....*....|....*....|....*..
gi 121247390 265 PYQCEHsgCGKAFATGYGLKSHfRTHT 291
Cdd:COG5189  398 PYRCEV--CDKRYKNLNGLKYH-RKHS 421
zf-H2C2_2 pfam13465
Zinc-finger double domain;
252-279 1.12e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 39.66  E-value: 1.12e-04
                          10        20
                  ....*....|....*....|....*...
gi 121247390  252 HLKVHERSHTGDRPYQCEHsgCGKAFAT 279
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPE--CGKSFKS 26
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
220-436 1.49e-04

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 44.69  E-value: 1.49e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 121247390 220 HATRVTPKS-QQSGEKAFRC-KYDGCGKLYTTAHHLKVHERSHTGDRPYQCEHSGCGKAFATGYGLKSHFRTHTGEKPYR 297
Cdd:COG5048   14 SVLSSTPKStLKSLSNAPRPdSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDKSFSRPLELSRHLRTHHNNPSDL 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 121247390 298 CSEDNCTKSFKTSGDlQKHIRTHTGERPFKCPIEGCGRSFTTSNIRKVHIRTHTGErpyyCTEPGCGRAFASATNYKNHV 377
Cdd:COG5048   94 NSKSLPLSNSKASSS-SLSSSSSNSNDNNLLSSHSLPPSSRDPQLPDLLSISNLRN----NPLPGNNSSSVNTPQSNSLH 168

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 121247390 378 RIHTGEkpyvctvPGCDKRFTEYSSLYKHHVVHTHSKPYNCNHCGKTYKQISTLAMHKR 436
Cdd:COG5048  169 PPLPAN-------SLSKDPSSNLSLLISSNVSTSIPSSSENSPLSSSYSIPSSSSDQNL 220
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
227-347 1.52e-04

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 44.69  E-value: 1.52e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 121247390 227 KSQQSGEKAFRCKYDGCGKLY----TTAHHLKVHERSH-TGDRPYQCEHSGCGKAFATGYGLKSHFRTHTGEKPYRCSED 301
Cdd:COG5048  343 ILLHTSISPAKEKLLNSSSKFspllNNEPPQSLQQYKDlKNDKKSETLSNSCIRNFKRDSNLSLHIITHLSFRPYNCKNP 422

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 121247390 302 NCTKSFKTSGDLQKHIRTHTGERPFKCpiEGCGRSFTTSNIRKVHI 347
Cdd:COG5048  423 PCSKSFNRHYNLIPHKKIHTNHAPLLC--SILKSFRRDLDLSNHGK 466
zf-H2C2_2 pfam13465
Zinc-finger double domain;
372-398 1.55e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 39.28  E-value: 1.55e-04
                          10        20
                  ....*....|....*....|....*..
gi 121247390  372 NYKNHVRIHTGEKPYVCTVpgCDKRFT 398
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPE--CGKSFK 25
zf-C2H2_8 pfam15909
C2H2-type zinc ribbon; This family carries three zinc-fingers in tandem.
 298-414 9.41e-04

C2H2-type zinc ribbon; This family carries three zinc-fingers in tandem.


Pssm-ID: 464935 [Multi-domain]  Cd Length: 98  Bit Score: 38.94  E-value: 9.41e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 121247390  298 CSEDNCTKSFKTSGDLQKHIRTHTgerPFKCPIEGcgrsfttsnirkvhirthtgeRPYYCTEPGCGRAFASATNYKNHV 377
Cdd:pfam15909   2 CSSPGCCLSFPSVRDLAQHLRTHC---PPTQSLEG---------------------KLFRCSALSCTETFPSMQELVAHS 57

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 121247390  378 RIHTGEKPYVcTVPGCDKRFTEYSSLYKH-HVVHTHSK 414
Cdd:pfam15909  58 KLHYKPNRYF-KCENCLLRFRTHRSLFKHlHVCAEHAQ 94
zf-C2H2 pfam00096
Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two ...
 296-320 1.56e-03

Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter.


Pssm-ID: 395048 [Multi-domain]  Cd Length: 23  Bit Score: 36.12  E-value: 1.56e-03
                          10        20
                  ....*....|....*....|....*
gi 121247390  296 YRCSEdnCTKSFKTSGDLQKHIRTH 320
Cdd:pfam00096   1 YKCPD--CGKSFSRKSNLKRHLRTH 23
zf-H2C2_2 pfam13465
Zinc-finger double domain;
344-369 1.75e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.20  E-value: 1.75e-03
                          10        20
                  ....*....|....*....|....*.
gi 121247390  344 KVHIRTHTGERPYYCTEpgCGRAFAS 369
Cdd:pfam13465   3 KRHMRTHTGEKPYKCPE--CGKSFKS 26
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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