|
Name |
Accession |
Description |
Interval |
E-value |
| pgi |
PRK00179 |
glucose-6-phosphate isomerase; Reviewed |
1-554 |
0e+00 |
|
glucose-6-phosphate isomerase; Reviewed
Pssm-ID: 234679 Cd Length: 548 Bit Score: 1057.85 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254553458 1 MAALTRNPQFQKLLEwHRANSANLKLRELFEADPERFNNFSLNLntnhGHILVDYSKNLVNKEVMQMLVELAKSRGVEAA 80
Cdd:PRK00179 2 NINLTQTPAWQALQA-HADEIKDVHLRDLFAADPDRFERFSLTA----GGLLLDYSKNRITDETLALLLDLAREAGLEGA 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254553458 81 RDNMFSGSKINYTENRAVLHVALRNRSNTPIKVDGKDVMPEVNRVLDKMKSFCQRVRSGDWKGYTGKSITDIINIGIGGS 160
Cdd:PRK00179 77 RDAMFAGEKINTTEDRAVLHTALRNPSNTPILVDGQDVMPEVHAVLARMKAFAEAVRSGEWKGYTGKAITDVVNIGIGGS 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254553458 161 DLGPLMVTEALKPYSKGGPRVWFVSNIDGTHIAKTLASLSPETSLFIIASKTFTTQETITNAETAKEWFLEAAKDPSAVA 240
Cdd:PRK00179 157 DLGPVMVTEALRPYADPGLRVHFVSNVDGAHLAETLKKLDPETTLFIVASKTFTTQETLTNAHSARDWFLAAGGDEAAVA 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254553458 241 KHFVALSTNTAKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDHFEQLLSGAHWMDQHFLKTPLEKNAPVLL 320
Cdd:PRK00179 237 KHFVAVSTNAEAVAEFGIDPDNMFGFWDWVGGRYSLWSAIGLSIALAIGPDNFEELLAGAHAMDEHFRTAPLEKNLPVLL 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254553458 321 ALLGIWYINCYGCETHALLPYDQYMHRFAAYFQQGDMESNGKYITKSGARVDHQTGPIVWGEPGTNGQHAFYQLIHQGTK 400
Cdd:PRK00179 317 ALIGVWYRNFFGAQSHAVLPYDQYLHRFPAYLQQLEMESNGKSVDRDGTPVDYQTGPIIWGEPGTNGQHAFFQLLHQGTK 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254553458 401 MIPCDFLIPVQTQHPIRKglHHKILLANFLAQTEALMKGKLPEEARKELQAAGKSPEDLEKLLPHKVFEGNRPTNSIVFT 480
Cdd:PRK00179 397 LVPADFIAPAQPHNPLGD--HHDLLLANCFAQTEALMFGKTAEEVRAELRAKGLDEAEAEELAPHKVFPGNRPSTTILLD 474
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 254553458 481 KLTPFILGALIAMYEHKIFVQGIMWDINSFDQWGVELGKQLAKKIEPELEGSSAVTSHDSSTNGLISFIKQQRD 554
Cdd:PRK00179 475 RLTPFTLGALIALYEHKVFVQGVIWGINSFDQWGVELGKQLAKRILPELEGDSEASAHDSSTNGLINRYRAWRG 548
|
|
| PGI |
pfam00342 |
Phosphoglucose isomerase; Phosphoglucose isomerase catalyzes the interconversion of ... |
54-546 |
0e+00 |
|
Phosphoglucose isomerase; Phosphoglucose isomerase catalyzes the interconversion of glucose-6-phosphate and fructose-6-phosphate.
Pssm-ID: 395271 Cd Length: 487 Bit Score: 941.52 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254553458 54 DYSKNLVNKEVMQMLVELAKSRGVEAARDNMFSGSKINYTENRAVLHVALRNRSNTPIKVDGKDVMPEVNRVLDKMKSFC 133
Cdd:pfam00342 1 DYSKNHINDEILTALVKLAEERGVDAAREAMFNGEKINSTENRAVLHVALRNRSNTPIYVDGKDVMPEVNAVLAKMKSFS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254553458 134 QRVRSGDWKGYTGKSITDIINIGIGGSDLGPLMVTEALKPYSKGGPRVWFVSNIDGTHIAKTLASLSPETSLFIIASKTF 213
Cdd:pfam00342 81 ERVRSGEWKGYTGKAITDVVNIGIGGSDLGPVMVTEALKPYSGRDLDVHFVSNVDGTHIAEVLKKLNPETTLFIVASKTF 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254553458 214 TTQETITNAETAKEWFLEAAKDPSAVAKHFVALSTNTAKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDHF 293
Cdd:pfam00342 161 TTAETMTNAESAKEWLLKALKDDSAVAKHFIALSTNAEKVEEFGIDTKNMFEFWDWVGGRYSLWSAIGLPIALSIGFENF 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254553458 294 EQLLSGAHWMDQHFLKTPLEKNAPVLLALLGIWYINCYGCETHALLPYDQYMHRFAAYFQQGDMESNGKYITKSGARVDH 373
Cdd:pfam00342 241 QQLLEGAHAMDKHFLSAPPEKNIPVLLALLGVWYNNFFGAQTHAILPYDQYLHRFPAYLQQLDMESNGKYVTRDGVLVDH 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254553458 374 QTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHPiRKGLHHKILLANFLAQTEALMKGKLPEEARKELQAAg 453
Cdd:pfam00342 321 QTGPIIFGEPGTNGQHAFYQLIHQGTRLIPCDFIGAVQSQNP-ENGDHHKILLSNFFAQTEALMVGKSPEEVRKELAAA- 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254553458 454 kspeDLEKLLPHKVFEGNRPTNSIVFTKLTPFILGALIAMYEHKIFVQGIMWDINSFDQWGVELGKQLAKKIEPELEGSS 533
Cdd:pfam00342 399 ----DVEHLIPHKTFTGNRPSNSILVQKLTPATLGALIAMYEHKIFVQGAIWGINSFDQWGVELGKVLAKSILPELENSN 474
|
490
....*....|...
gi 254553458 534 AVTSHDSSTNGLI 546
Cdd:pfam00342 475 KVSSHDSSTNGLI 487
|
|
| Pgi |
COG0166 |
Glucose-6-phosphate isomerase [Carbohydrate transport and metabolism]; Glucose-6-phosphate ... |
36-551 |
0e+00 |
|
Glucose-6-phosphate isomerase [Carbohydrate transport and metabolism]; Glucose-6-phosphate isomerase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 439936 Cd Length: 484 Bit Score: 751.97 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254553458 36 RFNNFSLNLntnhGHILVDYSKNLVNKEVMQMLVELAKSrgvEAARDNMFSGSKINYTENRAVLHVALRNRSntpikvDG 115
Cdd:COG0166 12 RFERFSLEA----AGLLLDYSKNRITDETLELLLELAEE---EEAREALFAGEKINPTEGRAVLHGALRLPE------AG 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254553458 116 KDVMPEVNRVLDKMKSFCQRVRsgdwkgyTGKSITDIINIGIGGSDLGPLMVTEALKPYSKGGPRVWFVSNIDGTHIAKT 195
Cdd:COG0166 79 EDVMPEVREELARIKAFAEKVR-------TGKRITDVVNIGIGGSDLGPRAVIEALKPYFRDGPRVHFVSNVDPDYLAEL 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254553458 196 LASLSPETSLFIIASKTFTTQETITNAETAKEWFLEAAKDpsAVAKHFVALSTNTAKVKEFGIDP-QNMFEFWDWVGGRY 274
Cdd:COG0166 152 LAGLDPETTLFIVISKSGTTQETLTNARVAREWLEKAGGE--DAAKHFVAVTDNAGALRAFGIDEgYNTFPFPDWVGGRY 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254553458 275 SLWSAIGLSIALHVGFDhFEQLLSGAHWMDQHFLKTPLEKNAPVLLALLGIWYINCYGCETHALLPYDQYMHRFAAYFQQ 354
Cdd:COG0166 230 SVLSAVGLLPAAAIGID-FEELLAGAHAMDEHFRTAPLEENPPVLLALLGIWYRNFKGAETEAVLPYDQRLERFPAWLQQ 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254553458 355 GDMESNGKYITKSGARVDHQTGPIvwGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHPIrkglhHKILLANFlaQTE 434
Cdd:COG0166 309 LWMESNGKSVDRDGNPVGYGTGPV--GEPGTTDQHSFGQLLHQGTRDIPVTFIAVAEPHHDI-----PDLLLANL--QGL 379
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254553458 435 ALMKGKLPEEARK-ELQAAgkspedlekllPHKVFEGNRPTNSIVFTKLTPFILGALIAMYEHKIFVQGIMWDINSFDQW 513
Cdd:COG0166 380 ALLAGKTLDEVLAlAAEAT-----------PHALFPGNRPSNTILLPKLTPYTLGALIALYEHAVFVQGVLWGINPFDQP 448
|
490 500 510
....*....|....*....|....*....|....*...
gi 254553458 514 GVELGKQLAKKIEPELEGSSAVTshDSSTNGLISFIKQ 551
Cdd:COG0166 449 GVELGKKLAFALLGKLGGEEAAA--GDSTEALLKRLRA 484
|
|
| SIS_PGI_2 |
cd05016 |
Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification ... |
334-525 |
1.22e-90 |
|
Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of glucose 6-phosphate to fructose 6-phosphate. As an extracellular protein, PGI also has functions equivalent to neuroleukin (NLK), autocrine motility factor (AMF), and maturation factor (MF). Evidence suggests that PGI, NLK, AMF, and MF are closely related or identical. NLK is a neurotrophic growth factor that promotes regeneration and survival of neurons. The dimeric form of NLK has isomerase function, whereas its monomeric form carries out neurotrophic activity. AMF is a cytokine that stimulates cell migration and metastasis. MF mediates the differentiation of human myeloid leukemic HL-60 cells to terminal monocytic cells.
Pssm-ID: 240147 Cd Length: 164 Bit Score: 275.63 E-value: 1.22e-90
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254553458 334 ETHALLPYDQYMHRFAAYFQQGDMESNGKYITKSGArvDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQ 413
Cdd:cd05016 1 KTHALLPYSQRLERFPAWLQQLDMESNGKSVTRDGE--DYPTGPIPWGAPGTNDQHSFFQLIHQGTKDKPVDFIAVKKPQ 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254553458 414 H----PIRKGLHHKILLANFLAQTEALMkgklpeearkelqaagkspedlekllphkvFEGNRPTNSIVFTKLTPFILGA 489
Cdd:cd05016 79 NdvldYLAGKTLHDLLLANCLATREALM------------------------------FPGGRPSNTIVLPELTPYTLGA 128
|
170 180 190
....*....|....*....|....*....|....*.
gi 254553458 490 LIAMYEHKIFVQGIMWDINSFDQWGVELGKQLAKKI 525
Cdd:cd05016 129 LLALYEHKTAVQGALLGINPFDQPGVELGKKLAKKI 164
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| pgi |
PRK00179 |
glucose-6-phosphate isomerase; Reviewed |
1-554 |
0e+00 |
|
glucose-6-phosphate isomerase; Reviewed
Pssm-ID: 234679 Cd Length: 548 Bit Score: 1057.85 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254553458 1 MAALTRNPQFQKLLEwHRANSANLKLRELFEADPERFNNFSLNLntnhGHILVDYSKNLVNKEVMQMLVELAKSRGVEAA 80
Cdd:PRK00179 2 NINLTQTPAWQALQA-HADEIKDVHLRDLFAADPDRFERFSLTA----GGLLLDYSKNRITDETLALLLDLAREAGLEGA 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254553458 81 RDNMFSGSKINYTENRAVLHVALRNRSNTPIKVDGKDVMPEVNRVLDKMKSFCQRVRSGDWKGYTGKSITDIINIGIGGS 160
Cdd:PRK00179 77 RDAMFAGEKINTTEDRAVLHTALRNPSNTPILVDGQDVMPEVHAVLARMKAFAEAVRSGEWKGYTGKAITDVVNIGIGGS 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254553458 161 DLGPLMVTEALKPYSKGGPRVWFVSNIDGTHIAKTLASLSPETSLFIIASKTFTTQETITNAETAKEWFLEAAKDPSAVA 240
Cdd:PRK00179 157 DLGPVMVTEALRPYADPGLRVHFVSNVDGAHLAETLKKLDPETTLFIVASKTFTTQETLTNAHSARDWFLAAGGDEAAVA 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254553458 241 KHFVALSTNTAKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDHFEQLLSGAHWMDQHFLKTPLEKNAPVLL 320
Cdd:PRK00179 237 KHFVAVSTNAEAVAEFGIDPDNMFGFWDWVGGRYSLWSAIGLSIALAIGPDNFEELLAGAHAMDEHFRTAPLEKNLPVLL 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254553458 321 ALLGIWYINCYGCETHALLPYDQYMHRFAAYFQQGDMESNGKYITKSGARVDHQTGPIVWGEPGTNGQHAFYQLIHQGTK 400
Cdd:PRK00179 317 ALIGVWYRNFFGAQSHAVLPYDQYLHRFPAYLQQLEMESNGKSVDRDGTPVDYQTGPIIWGEPGTNGQHAFFQLLHQGTK 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254553458 401 MIPCDFLIPVQTQHPIRKglHHKILLANFLAQTEALMKGKLPEEARKELQAAGKSPEDLEKLLPHKVFEGNRPTNSIVFT 480
Cdd:PRK00179 397 LVPADFIAPAQPHNPLGD--HHDLLLANCFAQTEALMFGKTAEEVRAELRAKGLDEAEAEELAPHKVFPGNRPSTTILLD 474
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 254553458 481 KLTPFILGALIAMYEHKIFVQGIMWDINSFDQWGVELGKQLAKKIEPELEGSSAVTSHDSSTNGLISFIKQQRD 554
Cdd:PRK00179 475 RLTPFTLGALIALYEHKVFVQGVIWGINSFDQWGVELGKQLAKRILPELEGDSEASAHDSSTNGLINRYRAWRG 548
|
|
| PGI |
pfam00342 |
Phosphoglucose isomerase; Phosphoglucose isomerase catalyzes the interconversion of ... |
54-546 |
0e+00 |
|
Phosphoglucose isomerase; Phosphoglucose isomerase catalyzes the interconversion of glucose-6-phosphate and fructose-6-phosphate.
Pssm-ID: 395271 Cd Length: 487 Bit Score: 941.52 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254553458 54 DYSKNLVNKEVMQMLVELAKSRGVEAARDNMFSGSKINYTENRAVLHVALRNRSNTPIKVDGKDVMPEVNRVLDKMKSFC 133
Cdd:pfam00342 1 DYSKNHINDEILTALVKLAEERGVDAAREAMFNGEKINSTENRAVLHVALRNRSNTPIYVDGKDVMPEVNAVLAKMKSFS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254553458 134 QRVRSGDWKGYTGKSITDIINIGIGGSDLGPLMVTEALKPYSKGGPRVWFVSNIDGTHIAKTLASLSPETSLFIIASKTF 213
Cdd:pfam00342 81 ERVRSGEWKGYTGKAITDVVNIGIGGSDLGPVMVTEALKPYSGRDLDVHFVSNVDGTHIAEVLKKLNPETTLFIVASKTF 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254553458 214 TTQETITNAETAKEWFLEAAKDPSAVAKHFVALSTNTAKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDHF 293
Cdd:pfam00342 161 TTAETMTNAESAKEWLLKALKDDSAVAKHFIALSTNAEKVEEFGIDTKNMFEFWDWVGGRYSLWSAIGLPIALSIGFENF 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254553458 294 EQLLSGAHWMDQHFLKTPLEKNAPVLLALLGIWYINCYGCETHALLPYDQYMHRFAAYFQQGDMESNGKYITKSGARVDH 373
Cdd:pfam00342 241 QQLLEGAHAMDKHFLSAPPEKNIPVLLALLGVWYNNFFGAQTHAILPYDQYLHRFPAYLQQLDMESNGKYVTRDGVLVDH 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254553458 374 QTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHPiRKGLHHKILLANFLAQTEALMKGKLPEEARKELQAAg 453
Cdd:pfam00342 321 QTGPIIFGEPGTNGQHAFYQLIHQGTRLIPCDFIGAVQSQNP-ENGDHHKILLSNFFAQTEALMVGKSPEEVRKELAAA- 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254553458 454 kspeDLEKLLPHKVFEGNRPTNSIVFTKLTPFILGALIAMYEHKIFVQGIMWDINSFDQWGVELGKQLAKKIEPELEGSS 533
Cdd:pfam00342 399 ----DVEHLIPHKTFTGNRPSNSILVQKLTPATLGALIAMYEHKIFVQGAIWGINSFDQWGVELGKVLAKSILPELENSN 474
|
490
....*....|...
gi 254553458 534 AVTSHDSSTNGLI 546
Cdd:pfam00342 475 KVSSHDSSTNGLI 487
|
|
| Pgi |
COG0166 |
Glucose-6-phosphate isomerase [Carbohydrate transport and metabolism]; Glucose-6-phosphate ... |
36-551 |
0e+00 |
|
Glucose-6-phosphate isomerase [Carbohydrate transport and metabolism]; Glucose-6-phosphate isomerase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 439936 Cd Length: 484 Bit Score: 751.97 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254553458 36 RFNNFSLNLntnhGHILVDYSKNLVNKEVMQMLVELAKSrgvEAARDNMFSGSKINYTENRAVLHVALRNRSntpikvDG 115
Cdd:COG0166 12 RFERFSLEA----AGLLLDYSKNRITDETLELLLELAEE---EEAREALFAGEKINPTEGRAVLHGALRLPE------AG 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254553458 116 KDVMPEVNRVLDKMKSFCQRVRsgdwkgyTGKSITDIINIGIGGSDLGPLMVTEALKPYSKGGPRVWFVSNIDGTHIAKT 195
Cdd:COG0166 79 EDVMPEVREELARIKAFAEKVR-------TGKRITDVVNIGIGGSDLGPRAVIEALKPYFRDGPRVHFVSNVDPDYLAEL 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254553458 196 LASLSPETSLFIIASKTFTTQETITNAETAKEWFLEAAKDpsAVAKHFVALSTNTAKVKEFGIDP-QNMFEFWDWVGGRY 274
Cdd:COG0166 152 LAGLDPETTLFIVISKSGTTQETLTNARVAREWLEKAGGE--DAAKHFVAVTDNAGALRAFGIDEgYNTFPFPDWVGGRY 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254553458 275 SLWSAIGLSIALHVGFDhFEQLLSGAHWMDQHFLKTPLEKNAPVLLALLGIWYINCYGCETHALLPYDQYMHRFAAYFQQ 354
Cdd:COG0166 230 SVLSAVGLLPAAAIGID-FEELLAGAHAMDEHFRTAPLEENPPVLLALLGIWYRNFKGAETEAVLPYDQRLERFPAWLQQ 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254553458 355 GDMESNGKYITKSGARVDHQTGPIvwGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHPIrkglhHKILLANFlaQTE 434
Cdd:COG0166 309 LWMESNGKSVDRDGNPVGYGTGPV--GEPGTTDQHSFGQLLHQGTRDIPVTFIAVAEPHHDI-----PDLLLANL--QGL 379
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254553458 435 ALMKGKLPEEARK-ELQAAgkspedlekllPHKVFEGNRPTNSIVFTKLTPFILGALIAMYEHKIFVQGIMWDINSFDQW 513
Cdd:COG0166 380 ALLAGKTLDEVLAlAAEAT-----------PHALFPGNRPSNTILLPKLTPYTLGALIALYEHAVFVQGVLWGINPFDQP 448
|
490 500 510
....*....|....*....|....*....|....*...
gi 254553458 514 GVELGKQLAKKIEPELEGSSAVTshDSSTNGLISFIKQ 551
Cdd:COG0166 449 GVELGKKLAFALLGKLGGEEAAA--GDSTEALLKRLRA 484
|
|
| PLN02649 |
PLN02649 |
glucose-6-phosphate isomerase |
1-547 |
0e+00 |
|
glucose-6-phosphate isomerase
Pssm-ID: 215351 [Multi-domain] Cd Length: 560 Bit Score: 716.43 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254553458 1 MAALTRNPQFQKLLEwHRANSANLKLRELFeADPERFNNFSLNLNTnhghILVDYSKNLVNKEVMQMLVELAKSRGVEAA 80
Cdd:PLN02649 5 TLLISDTPAWKRLVA-HVYQIKKTHLRELL-NDAERCQSMIAEFDG----IYLDYSRQRVTDETMELLFPLAEAANLFEK 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254553458 81 RDNMFSGSKINYTENRAVLHVALRNRSNTPIKVDGKDVMPEVNRVLDKMKSFCQRVRSGDWKGYTGKSITDIINIGIGGS 160
Cdd:PLN02649 79 IEAMFSGEIINSTEDRAVLHVALRAPRLAPILVDGKNVVPEVWEVLDKIKAFSEDVRSGKWKGATGKRFTNVVSIGIGGS 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254553458 161 DLGPLMVTEALKPYSKG-----GPRVWFVSNIDGTHIAKTLASLSPETSLFIIASKTFTTQETITNAETAKEWFLEAAkD 235
Cdd:PLN02649 159 FLGPLFVHEALATDPEAlksakGRKLRFLANVDPVDIARQIAQLDPETTLVVVVSKTFTTAETMLNARTVRKWLRDAL-G 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254553458 236 PSAVAKHFVALSTNTAKVKEFGIDPQNMFEFWDWVGGRYSLWSAIG-LSIALHVGFDHFEQLLSGAHWMDQHFLKTPLEK 314
Cdd:PLN02649 238 GLAVAKHMVAVSTNLLLVNKFGIDPWNAFPFWDWVGGRYSVCSAVGlLPLSLQYGFDVVEEFLEGAASMDEHFRTAPLKE 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254553458 315 NAPVLLALLGIWYINCYGCETHALLPYDQYMHRFAAYFQQGDMESNGKYITKSGARVDHQTGPIVWGEPGTNGQHAFYQL 394
Cdd:PLN02649 318 NIPVLLGLLSVWNSSFLGYPARAILPYSQALLKFAPHIQQLDMESNGKGVDLDGNPLPVNTGEIDFGEPGTNGQHSFYQL 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254553458 395 IHQGtKMIPCDFLIPVQTQHPIRKGL-----HHKILLANFLAQTEALMKGKLPEEARKElqaagkspEDLEKLLPHKVFE 469
Cdd:PLN02649 398 IHQG-RNIPCDFIGVVRSQQPVHLWLgegvsNHDELMSNFFAQPDALAYGKTPEQLRAE--------GVPEELIPHKVFA 468
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254553458 470 GNRPTNSIVFTKLTPFILGALIAMYEHKIFVQGIMWDINSFDQWGVELGKQLAKKIEPELEGSS----AVTSHDSSTNGL 545
Cdd:PLN02649 469 GNRPSLSILLPELTAYTVGQLLALYEHRVAVQGFIWNINSFDQWGVELGKALAKRVRAVLNEARtkgePVEGFNSSTTAL 548
|
..
gi 254553458 546 IS 547
Cdd:PLN02649 549 LN 550
|
|
| PTZ00430 |
PTZ00430 |
glucose-6-phosphate isomerase; Provisional |
3-525 |
0e+00 |
|
glucose-6-phosphate isomerase; Provisional
Pssm-ID: 185612 Cd Length: 552 Bit Score: 594.30 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254553458 3 ALTRNPQFQKLLEwHRANSANLKLRELFeADPERfnnfSLNLNTNHGHILVDYSKNLVNKEVMQMLVELAKSRGVEAARD 82
Cdd:PTZ00430 2 DLESLKSYKNLLS-LAEKLKKVHLRDLL-KDEER----NKSLIKEFKGVTLDLSRQRLDEETLKLLIELAEEAKLKEKIK 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254553458 83 NMFSGSKINYTENRAVLHVALRNRSNTPIKVDGKDVMPEVNRVLDKMKSFCQRVRSGDWKGYTGKSITDIINIGIGGSDL 162
Cdd:PTZ00430 76 DMFNGEKINTTENRAVLHTALRAPRGEKVVVDGKNVLEDVHEVLDRIKKFSDKIRSGEILGSTGKKLKNVICIGIGGSYL 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254553458 163 GPLMVTEALKPYSKG-----GPRVWFVSNIDGTHIAKTLASLSPETSLFIIASKTFTTQETITNAETAKEWFLEAAKDPS 237
Cdd:PTZ00430 156 GTEFVYEALRTYGEAreaskGRKLRFLANVDPIDVRRATEGLDPEETLVVIISKTFTTAETMLNAKTVRQWLLDNIKSKE 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254553458 238 AVAKHFVALSTNTAKVKEFGIDPQNMFEFWDWVGGRYSLWSAIG-LSIALHVGFDHFEQLLSGAHWMDQHFLKTPLEKNA 316
Cdd:PTZ00430 236 ALSKHLCAVSTNLKLTSEFGIPDENVFGFWDWVGGRFSVTSAVGiLPLSIQFGYDIVQQFLNGCHDMDEHFRTAPLEENL 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254553458 317 PVLLALLGIWYINCYGCETHALLPYDQYMHRFAAYFQQGDMESNGKYITKSGARVDHQTGPIVWGEPGTNGQHAFYQLIH 396
Cdd:PTZ00430 316 PVLLGLTSFYNSTFLGYNCVAILPYCQALLKFPAHVQQLLMESNGKSVTLDGNTLDYNTGEIYFGEPGTNGQHSFYQLLH 395
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254553458 397 QGTkMIPCDFLIPVQTQHPIRKG----LHHKILLANFLAQTEALMKGKLPEEARKElqaaGKSPEdlekLLPHKVFEGNR 472
Cdd:PTZ00430 396 QGR-VVPSEFIGFAKSQNPIKLLgepvSNHDELMSNFFAQPDALAFGKTYEELEKE----GVPEE----LIPHKVFPGNR 466
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|...
gi 254553458 473 PTNSIVFTKLTPFILGALIAMYEHKIFVQGIMWDINSFDQWGVELGKQLAKKI 525
Cdd:PTZ00430 467 PSLLLLFPELNPYTIGQLLALYEHRTVVEGFLWNINSFDQWGVELGKVLAKDV 519
|
|
| pgi |
PRK14095 |
glucose-6-phosphate isomerase; Provisional |
10-531 |
6.22e-142 |
|
glucose-6-phosphate isomerase; Provisional
Pssm-ID: 237608 Cd Length: 533 Bit Score: 420.58 E-value: 6.22e-142
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254553458 10 FQKLLEwhrANSANLKLRELFEADPERFNNFSLNLntnhGHILVDYSKNLVNKEVMQMLVELAKSRGVEAARDNMFSGSK 89
Cdd:PRK14095 13 FKILQE---LAPEPLDLTLPGVLSEERIKKYSLSG----EGFTYNYATERVDDRILAALQNLADEAELIEKMKAMQNGAV 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254553458 90 INY-----TENRAVLHVALRNR-SNTPIKVDGKDVMPEVNRVLDKMKSFCQRVRSGDWKGYTGKSITDIINIGIGGSDLG 163
Cdd:PRK14095 86 INRiegfpSENRPVLHTATRGQvGDSVLTDEAEDMAEFSKRELERLAEFLKKVRSGEIKNSNGKKFTTVVQIGIGGSDLG 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254553458 164 PLMVTEALKPYSKGGPRVWFVSNIDGTHIAKTLASLSPETSLFIIASKTFTTQETITNAETAKEWFLEAAKDPsavAKHF 243
Cdd:PRK14095 166 PKALYLALKNYAKKDKRVHFISNVDPDDAAEVLSEIDLAKTLFIVVSKSGTTLETAANEEFVRDALKKAGLDY---KKHF 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254553458 244 VALSTNTAKVKefgiDPQN---MFEFWDWVGGRYSLWSAIGLS-IALHVGFDHFEQLLSGAHWMDQHFLKTPLEKNAPVL 319
Cdd:PRK14095 243 IAVTSEGSPMD----DESGyleVFHMWDSIGGRFSSTSMVGGVvLGFAFGFEVFKEFLKGAAAMDKAALNPNIRENLPLL 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254553458 320 LALLGIWYINCYGCETHALLPYDQYMHRFAAYFQQGDMESNGKYITKSGARVDHQTGPIVWGEPGTNGQHAFYQLIHQGT 399
Cdd:PRK14095 319 AALIGIWNRNFLGYPTTAVIPYSQALERFPAHLQQLDMESNGKSVNRFGEPINFKTGPIIWGEPGTNGQHSFFQLLHQGT 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254553458 400 KMIPCDFLIPVQTQH----PIRKGLHHKILLANFLAQTEALmkgklpeearkelqAAGKSPEDlekllPHKVFEGNRPTN 475
Cdd:PRK14095 399 DIVPVEFIGFKESQLgqdiVIQGSTSQQKLFANLIAQIIAL--------------ACGKENTN-----PNKNFKGNRPSS 459
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*.
gi 254553458 476 SIVFTKLTPFILGALIAMYEHKIFVQGIMWDINSFDQWGVELGKQLAKKIEPELEG 531
Cdd:PRK14095 460 LLVAKQLTPYTLGALLAHYENKVMFQGFCWNINSFDQEGVQLGKVLANQILGIMKG 515
|
|
| SIS_PGI_2 |
cd05016 |
Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification ... |
334-525 |
1.22e-90 |
|
Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of glucose 6-phosphate to fructose 6-phosphate. As an extracellular protein, PGI also has functions equivalent to neuroleukin (NLK), autocrine motility factor (AMF), and maturation factor (MF). Evidence suggests that PGI, NLK, AMF, and MF are closely related or identical. NLK is a neurotrophic growth factor that promotes regeneration and survival of neurons. The dimeric form of NLK has isomerase function, whereas its monomeric form carries out neurotrophic activity. AMF is a cytokine that stimulates cell migration and metastasis. MF mediates the differentiation of human myeloid leukemic HL-60 cells to terminal monocytic cells.
Pssm-ID: 240147 Cd Length: 164 Bit Score: 275.63 E-value: 1.22e-90
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254553458 334 ETHALLPYDQYMHRFAAYFQQGDMESNGKYITKSGArvDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQ 413
Cdd:cd05016 1 KTHALLPYSQRLERFPAWLQQLDMESNGKSVTRDGE--DYPTGPIPWGAPGTNDQHSFFQLIHQGTKDKPVDFIAVKKPQ 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254553458 414 H----PIRKGLHHKILLANFLAQTEALMkgklpeearkelqaagkspedlekllphkvFEGNRPTNSIVFTKLTPFILGA 489
Cdd:cd05016 79 NdvldYLAGKTLHDLLLANCLATREALM------------------------------FPGGRPSNTIVLPELTPYTLGA 128
|
170 180 190
....*....|....*....|....*....|....*.
gi 254553458 490 LIAMYEHKIFVQGIMWDINSFDQWGVELGKQLAKKI 525
Cdd:cd05016 129 LLALYEHKTAVQGALLGINPFDQPGVELGKKLAKKI 164
|
|
| SIS_PGI_1 |
cd05015 |
Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification ... |
123-286 |
2.16e-82 |
|
Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of glucose 6-phosphate to fructose 6-phosphate. As an extracellular protein, PGI also has functions equivalent to neuroleukin (NLK), autocrine motility factor (AMF), and maturation factor (MF). Evidence suggests that PGI, NLK, AMF, and MF are closely related or identical. NLK is a neurotrophic growth factor that promotes regeneration and survival of neurons. The dimeric form of NLK has isomerase function, whereas its monomeric form carries out neurotrophic activity. AMF is a cytokine that stimulates cell migration and metastasis. MF mediates the differentiation of human myeloid leukemic HL-60 cells to terminal monocytic cells.
Pssm-ID: 240146 Cd Length: 158 Bit Score: 253.99 E-value: 2.16e-82
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254553458 123 NRVLDKMKSFCQRVRSGdwkgytgKSITDIINIGIGGSDLGPLMVTEALKPYSKGGPRVWFVSNIDGTHIAKTLASLSPE 202
Cdd:cd05015 1 RAELERIKEFAEKVRSG-------KKITDVVVIGIGGSDLGPRAVYEALKPYFKGGLRLHFVSNVDPDDLAELLKKLDPE 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254553458 203 TSLFIIASKTFTTQETITNAETAKEWFLEAAKDpsAVAKHFVALSTNTAKVKE-FGIDPQNMFEFWDWVGGRYS-LWSAI 280
Cdd:cd05015 74 TTLFIVISKSGTTLETLANARLAREWLEEAGGD--DLAKHFVAITDNGSGLLKkAGIEGLNTFEIPDWVGGRFSvLSSVG 151
|
....*.
gi 254553458 281 GLSIAL 286
Cdd:cd05015 152 GLPLAL 157
|
|
| pgi |
PRK14096 |
glucose-6-phosphate isomerase; Provisional |
86-525 |
7.65e-48 |
|
glucose-6-phosphate isomerase; Provisional
Pssm-ID: 237609 [Multi-domain] Cd Length: 528 Bit Score: 174.30 E-value: 7.65e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254553458 86 SGSKINYTENRAVLHVALRNRSNTPikvdGKDVMPEVNRVLDKMKSFCQRVRSGDWKGYTGKSITDIINIGIGGSDLGPL 165
Cdd:PRK14096 55 AGAIANPDEGRMVGHYWLRNPELAP----TPEIRAEITETLAQIEAFAAKVHSGTIKPPNGEKFTDVLWIGIGGSALGPQ 130
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254553458 166 MVTEALKPYSKgGPRVWFVSNIDGTHIAKTLASLSPE--TSLFIIASKTFTTQETITNAETAKeWFLEAAKDPsaVAKHF 243
Cdd:PRK14096 131 FVAEALQPNSD-GLNIHFIDNTDPDGIDRVLAELGDRlaTTLVVVISKSGGTPETRNGMLEAK-AAYEAAGLD--FASHA 206
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254553458 244 VALSTNTAKVKEFGIDPQ--NMFEFWDWVGGRYSLWSAIGLSIALHVGFDHFEqLLSGAHWMDQHFLKTPLEKNAPVLLA 321
Cdd:PRK14096 207 VAITMKGSKLDQLAQSEGwlARFPMWDWVGGRTSETSAVGLLPAALQGIDIRA-FLAGAKQMDEATRVPDLKNNPAALLA 285
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254553458 322 LLgiWYI--NCYGCETHALLPYDQYMHRFAAYFQQGDMESNGKYITKSGARVdHQtGPIVWGEPGTNGQHAFYQLIHQGT 399
Cdd:PRK14096 286 LA--WYYagDGKGKKDMVVLPYKDRLLLFSRYLQQLVMESLGKELDLDGNVV-HQ-GIAVYGNKGSTDQHAYVQQLRDGV 361
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254553458 400 KMIPCDFL----IPVQTQHPIRKGLHHKILLANFLAQT-EALmkgklpeearkelqaagkspedlekllphkvFEGNRPT 474
Cdd:PRK14096 362 DNFFVTFIevleDRQGSSIEVEPGVTSGDYLSGFLQGTrQAL-------------------------------YENGRQS 410
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|.
gi 254553458 475 NSIVFTKLTPFILGALIAMYEHKIFVQGIMWDINSFDQWGVELGKQLAKKI 525
Cdd:PRK14096 411 ITITIPEVNPRTLGALIALFERAVGLYASLVNINAYHQPGVEAGKKAAAAI 461
|
|
| PRK00973 |
PRK00973 |
glucose-6-phosphate isomerase; Provisional |
123-538 |
6.93e-37 |
|
glucose-6-phosphate isomerase; Provisional
Pssm-ID: 179193 [Multi-domain] Cd Length: 446 Bit Score: 142.44 E-value: 6.93e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254553458 123 NRVLDKMKSFCQRVRSGDwkgytgksitDIINIGIGGSDLGPLMVTEALKP-----YSK---GGPRVWFVSNIDGTHIAK 194
Cdd:PRK00973 55 DRSLDSYEELKEWSKNFD----------NVVVLGIGGSALGNLALHYALNPlnwneLSKeerNGPRVFVLDNVDPEKTAS 124
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254553458 195 TLASLSPETSLFIIASKTFTTQETITNAETAKEWFLEAAKDPSavaKHFVALsTNTAK------VKEFGID----PQNmf 264
Cdd:PRK00973 125 ILDVIDLEKTLFNVISKSGNTAETLANYLIIRGILEKLGLDPK---KHLVFT-TDPEKgklkkiAEKEGYRtleiPEN-- 198
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254553458 265 efwdwVGGRYSLWSAIGLSIALHVGFDhFEQLLSGAHWMDQHFLKTPLEKNAPVLLALLGIWYINcYGCETHALLPYDQY 344
Cdd:PRK00973 199 -----VGGRFSVLTPVGLAPAAALGID-IEELLEGAKEMDKICEKEDIFKNPALLNALIHYLYYN-RGKNISVMMPYSER 271
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254553458 345 MHRFAAYFQQGDMESNGKyitksgaRVDHQTgPIvwGEPGTNGQHAFYQLIHQG--TKMI--------PCDFLIPvqTQH 414
Cdd:PRK00973 272 LKYFGDWYRQLWAESLGK-------KGVGQT-PV--KALGATDQHSQLQLYMEGpkDKIItflkvekyRRDVEIP--YEY 339
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254553458 415 PIRKGLHHkillanflaqteaLMKGKLPEEARKELQAAgkspedlEKLLPHKvfegNRPTNSIVFTKLTPFILGALIAMY 494
Cdd:PRK00973 340 EDIEELSY-------------LGGHKLSELINSEQKGT-------EIALTEN----GRPNVKITLDELNEYTVGQLFYMY 395
|
410 420 430 440
....*....|....*....|....*....|....*....|....
gi 254553458 495 EHKIFVQGIMWDINSFDQWGVELGkqlaKKIEPELEGSSAVTSH 538
Cdd:PRK00973 396 EMQTAFMGELLNINAFDQPGVELG----KKITYALLGRSGYEEE 435
|
|
| PRK03868 |
PRK03868 |
glucose-6-phosphate isomerase; Provisional |
147-525 |
2.90e-28 |
|
glucose-6-phosphate isomerase; Provisional
Pssm-ID: 235168 Cd Length: 410 Bit Score: 116.96 E-value: 2.90e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254553458 147 KSITDIINIGIGGSDLGPLMVTEALKPYSKGGPRVWFVSNIDGTHIAKTLASLSPETSLFIIASKTFTTQETITNAETAK 226
Cdd:PRK03868 56 ESIKNIVVIGIGGSSLGVKAIYSFLKNEKNNKKELHFLENTDPISINKTLSKINLENTLFIVISKSGTTIETISIFKYLL 135
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254553458 227 EWF---LEAAK------DPSAVAKHFvalsTNTAKVKEFGIdPQNmfefwdwVGGRYSLWSAIG---LSIAlhvGFDhFE 294
Cdd:PRK03868 136 SHFkldQELKKnflfitDPDSKLEQF----AKENNIKCFNI-PKN-------VGGRFSVLSAVGivpLALC---GYD-IK 199
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254553458 295 QLLSGAHWMDQHFlktpLEKNAPVLL--ALLGIWYINCYgcETHALLPYDQYMHRFAAYFQQGDMESNGKyITKSGARVd 372
Cdd:PRK03868 200 ALLEGAKACKDSF----FEQKEDHILkkAYFYATHKNAY--NINVLFSYSDALKGFNDWYVQLWGESLGK-KQGYKTRV- 271
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254553458 373 hqtGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIpvqtqhpirkglhhkilLANFLAQTealmkgKLPEEARKELQA- 451
Cdd:PRK03868 272 ---GLTPIGLIGSRDQHSFLQLIMEGPRDKTVTFIK-----------------IKDFQNAP------KIPNISLKGLESl 325
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254553458 452 ---AGKSPEDLEKL----LPHKVFEGNRPTNSIVFTKLTPFILGALIAMYEHKIFVQGIMWDINSFDQWGVELGKQLAKK 524
Cdd:PRK03868 326 dfvNGVSFNELINAqcdaTMEALIAEDIPVDVITLEKLDEFSIGYLIYYYELLTSAVGKMLGINTYDQPGVEVGKRILKE 405
|
.
gi 254553458 525 I 525
Cdd:PRK03868 406 K 406
|
|
| PRK09533 |
PRK09533 |
bifunctional transaldolase/phosoglucose isomerase; Validated |
126-303 |
3.00e-10 |
|
bifunctional transaldolase/phosoglucose isomerase; Validated
Pssm-ID: 236551 [Multi-domain] Cd Length: 948 Bit Score: 63.07 E-value: 3.00e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254553458 126 LDKMKSFCQRVRsgdwkgytGKSITDIINIGIGGSDLGPlmvtEALK---PYSKGGPRVWFVSNIDGTHIAKTLASLSPE 202
Cdd:PRK09533 440 LAEYEAFAEEVR--------AEGFTDAVVLGMGGSSLGP----EVLAetfGQRDGFPKLHVLDSTDPAQVRALEAAVDLA 507
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254553458 203 TSLFIIASKTFTTQEtiTNAetAKEWFLEAAKDP--SAVAKHFVALS---TNTAKVKE-------FGIDPQnmfefwdwV 270
Cdd:PRK09533 508 RTLFIVSSKSGGTLE--PNI--FKDYFFARVKEVlgAKAGRHFVAVTdpgSSLEKVAKedgfrkiFHGDPD--------I 575
|
170 180 190
....*....|....*....|....*....|...
gi 254553458 271 GGRYSLWSAIGLSIALHVGFDhFEQLLSGAHWM 303
Cdd:PRK09533 576 GGRYSVLSPFGLVPAAAAGID-VRALLDSALAM 607
|
|
| pgi |
PRK14097 |
glucose-6-phosphate isomerase; Provisional |
147-520 |
8.74e-10 |
|
glucose-6-phosphate isomerase; Provisional
Pssm-ID: 184504 Cd Length: 448 Bit Score: 61.01 E-value: 8.74e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254553458 147 KSITDIINIGIGGSDLGPLMVTEAL--------KPYSKGGPRVWFVSN-IDGTHIAKTLASLSPETSLFIIASKTFTTQE 217
Cdd:PRK14097 71 SDSDVLVVIGIGGSYLGARAAIEFLnhsfynllPKEQRKAPQIIFAGNsISSTYLADLLEYLKDKDFSINVISKSGTTTE 150
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254553458 218 T-----ITNAETAKEWFLEAAKdpsavaKHFVAlSTNTAK--VKEFGiDPQN--MFEFWDWVGGRYSLWSAIGLSIALHV 288
Cdd:PRK14097 151 PaiafrIFKELLEKKYGKEEAK------KRIYA-TTDKAKgaLKTLA-DAEGyeTFVIPDDVGGRFSVLTAVGLLPIAVA 222
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254553458 289 GFDhFEQLLSGAHWMDQHFLKTPLEKNAPVLLALL-GIWYINCYgcETHALLPYDQYMHRFAAYFQQGDMESNGK----- 362
Cdd:PRK14097 223 GID-IDALMKGAADARKDYSSSDLSENPAYQYAAVrNILYRKGY--TTEILVNYEPSLQYFSEWWKQLFGESEGKdqkgi 299
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254553458 363 YITKSGARVD-HQTGpivwgepgtngqhafyQLIHQGTKMIpcdFLIPVQTQHPirkglHHKILLA---------NFLAq 432
Cdd:PRK14097 300 FPASANFSTDlHSLG----------------QYIQEGRRNL---FETVIKVEKP-----RKDLTIPedeedldglNYLA- 354
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254553458 433 tealmkGK-LPEEARKELQAAgkspedlekLLPHkvFEGNRPTNSIVFTKLTPFILGALIAMYEHKIFVQGIMWDINSFD 511
Cdd:PRK14097 355 ------GKtVDFVNKKAFEGT---------LLAH--TDGGVPNIVVNIPELDEYTFGYLVYFFEKACAISGYLLGVNPFD 417
|
....*....
gi 254553458 512 QWGVELGKQ 520
Cdd:PRK14097 418 QPGVEAYKK 426
|
|
| SIS |
cd04795 |
SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and ... |
344-436 |
1.94e-04 |
|
SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars.
Pssm-ID: 240112 [Multi-domain] Cd Length: 87 Bit Score: 40.44 E-value: 1.94e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254553458 344 YMHRFAAYFQQGDMESngkyitksgarvdhqTGPIVWGEPGTNGQHAFyqLIHQGTKMIPCDFLIPVQTQhpirkglhhk 423
Cdd:cd04795 8 GSGAIAAYFALELLEL---------------TGIEVVALIATELEHAS--LLSLLRKGDVVIALSYSGRT---------- 60
|
90
....*....|...
gi 254553458 424 ILLANFLAQTEAL 436
Cdd:cd04795 61 EELLAALEIAKEL 73
|
|
| |
