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Conserved domains on  [gi|118026913|ref|NP_031853|]
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complement decay-accelerating factor transmembrane isoform isoform 1 precursor [Mus musculus]

Protein Classification

beta-2-glycoprotein 1( domain architecture ID 12867676)

beta-2-glycoprotein 1 is a heavily glycosylated plasma membrane-adhesion protein, which plays a role in blood coagulation and removal of apoptotic bodies

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PHA02927 super family cl33700
secreted complement-binding protein; Provisional
 92-279 2.32e-35

secreted complement-binding protein; Provisional


The actual alignment was detected with superfamily member PHA02927:

Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 130.93  E-value: 2.32e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118026913  92 CEKSCDT----PERLSFASLKKEYFNMNFfPVGTIVEYECRPGFRKQPSLSGKSTCLEDlVWSPVAQfCKKKSCPNPKDL 167
Cdd:PHA02927  16 CVLSCCTipsrPINMKFKNSVETDANANY-NIGDTIEYLCLPGYRKQKMGPIYAKCTGT-GWTLFNQ-CIKRRCPSPRDI 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118026913 168 DNGHINIpTGILFGSEINFSCNPGYRLVGITSILCTI--IGNTVdWDDEFPVCTEIFCPDPPKINNGIMRGESDSYKYSQ 245
Cdd:PHA02927  93 DNGQLDI-GGVDFGSSITYSCNSGYQLIGESKSYCELgsTGSMV-WNPEAPICESVKCQSPPSISNGRHNGYEDFYTDGS 170

                        170       180       190
                 ....*....|....*....|....*....|....
gi 118026913 246 VVIYSCDKGFILFGNSTIYCTvsksdVGQWSSPP 279
Cdd:PHA02927 171 VVTYSCNSGYSLIGNSGVLCS-----GGEWSDPP 199
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 34-93 5.01e-10

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


:

Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 54.78  E-value: 5.01e-10
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 118026913  34 CGPPPDIPNARpILGRHSKFAEQSKVAYSCNNGFKQVPdkSNIVVCLENGQWSSHETFCE 93
Cdd:cd00033    1 CPPPPVPENGT-VTGSKGSYSYGSTVTYSCNEGYTLVG--SSTITCTENGGWSPPPPTCE 57
 
Name Accession Description Interval E-value
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 92-279 2.32e-35

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 130.93  E-value: 2.32e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118026913  92 CEKSCDT----PERLSFASLKKEYFNMNFfPVGTIVEYECRPGFRKQPSLSGKSTCLEDlVWSPVAQfCKKKSCPNPKDL 167
Cdd:PHA02927  16 CVLSCCTipsrPINMKFKNSVETDANANY-NIGDTIEYLCLPGYRKQKMGPIYAKCTGT-GWTLFNQ-CIKRRCPSPRDI 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118026913 168 DNGHINIpTGILFGSEINFSCNPGYRLVGITSILCTI--IGNTVdWDDEFPVCTEIFCPDPPKINNGIMRGESDSYKYSQ 245
Cdd:PHA02927  93 DNGQLDI-GGVDFGSSITYSCNSGYQLIGESKSYCELgsTGSMV-WNPEAPICESVKCQSPPSISNGRHNGYEDFYTDGS 170

                        170       180       190
                 ....*....|....*....|....*....|....
gi 118026913 246 VVIYSCDKGFILFGNSTIYCTvsksdVGQWSSPP 279
Cdd:PHA02927 171 VVTYSCNSGYSLIGNSGVLCS-----GGEWSDPP 199
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 223-283 2.20e-15

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 69.80  E-value: 2.20e-15
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 118026913 223 CPDPPKINNGIMRGESDSYKYSQVVIYSCDKGFILFGNSTIYCTVSksdvGQWSSPPPQCI 283
Cdd:cd00033    1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTEN----GGWSPPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 223-282 5.41e-13

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 63.31  E-value: 5.41e-13
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 118026913   223 CPDPPKINNGIMRGESDSYKYSQVVIYSCDKGFILFGNSTIYCTVSksdvGQWSSPPPQC 282
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITCLEN----GTWSPPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
223-282 5.16e-12

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 60.59  E-value: 5.16e-12
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 118026913  223 CPDPPKINNGIMRGESDSYKYSQVVIYSCDKGFILFGNSTIYCTVSksdvGQWSSPPPQC 282
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCQED----GTWSPPFPEC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 34-93 5.01e-10

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 54.78  E-value: 5.01e-10
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 118026913  34 CGPPPDIPNARpILGRHSKFAEQSKVAYSCNNGFKQVPdkSNIVVCLENGQWSSHETFCE 93
Cdd:cd00033    1 CPPPPVPENGT-VTGSKGSYSYGSTVTYSCNEGYTLVG--SSTITCTENGGWSPPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 34-92 1.90e-08

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 50.22  E-value: 1.90e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 118026913    34 CGPPPDIPNARpILGRHSKFAEQSKVAYSCNNGFKQVPdkSNIVVCLENGQWSSHETFC 92
Cdd:smart00032   1 CPPPPDIENGT-VTSSSGTYSYGDTVTYSCDPGYTLIG--SSTITCLENGTWSPPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
34-92 2.01e-07

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 47.49  E-value: 2.01e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 118026913   34 CGPPPDIPNARPIlGRHSKFAEQSKVAYSCNNGFKQVPdkSNIVVCLENGQWSSHETFC 92
Cdd:pfam00084   1 CPPPPDIPNGKVS-ATKNEYNYGASVSYECDPGYRLVG--SPTITCQEDGTWSPPFPEC 56
 
Name Accession Description Interval E-value
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 92-279 2.32e-35

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 130.93  E-value: 2.32e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118026913  92 CEKSCDT----PERLSFASLKKEYFNMNFfPVGTIVEYECRPGFRKQPSLSGKSTCLEDlVWSPVAQfCKKKSCPNPKDL 167
Cdd:PHA02927  16 CVLSCCTipsrPINMKFKNSVETDANANY-NIGDTIEYLCLPGYRKQKMGPIYAKCTGT-GWTLFNQ-CIKRRCPSPRDI 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118026913 168 DNGHINIpTGILFGSEINFSCNPGYRLVGITSILCTI--IGNTVdWDDEFPVCTEIFCPDPPKINNGIMRGESDSYKYSQ 245
Cdd:PHA02927  93 DNGQLDI-GGVDFGSSITYSCNSGYQLIGESKSYCELgsTGSMV-WNPEAPICESVKCQSPPSISNGRHNGYEDFYTDGS 170

                        170       180       190
                 ....*....|....*....|....*....|....
gi 118026913 246 VVIYSCDKGFILFGNSTIYCTvsksdVGQWSSPP 279
Cdd:PHA02927 171 VVTYSCNSGYSLIGNSGVLCS-----GGEWSDPP 199
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 223-283 2.20e-15

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 69.80  E-value: 2.20e-15
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 118026913 223 CPDPPKINNGIMRGESDSYKYSQVVIYSCDKGFILFGNSTIYCTVSksdvGQWSSPPPQCI 283
Cdd:cd00033    1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTEN----GGWSPPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 223-282 5.41e-13

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 63.31  E-value: 5.41e-13
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 118026913   223 CPDPPKINNGIMRGESDSYKYSQVVIYSCDKGFILFGNSTIYCTVSksdvGQWSSPPPQC 282
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITCLEN----GTWSPPPPTC 56
PHA02639 PHA02639
EEV host range protein; Provisional
 96-288 1.43e-12

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 67.77  E-value: 1.43e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118026913  96 CDTPERLSFASLKKEyfnMNFFPVGTIVEYECRPGFrkqpSLSGKS--TCLED---LVWSPVAQFCKKKSCPNPKDLDNG 170
Cdd:PHA02639  22 CDKPDDISNGFITEL---MEKYEIGKLIEYTCNTDY----ALIGDRfrTCIKDknnAIWSNKAPFCMLKECNDPPSIING 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118026913 171 HI-NIPTGILFGSEINFSCNP----GYRLVGITSILCTiigNTVDWDDEFPVCTEIFCpDPPKINNGIMRG--ESDSYKY 243
Cdd:PHA02639  95 KIyNKREMYKVGDEIYYVCNEhkgvQYSLVGNEKITCI---QDKSWKPDPPICKMINC-RFPALQNGYINGipSNKKFYY 170

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 118026913 244 SQVVIYSCDKGFILFGNSTIYCTVSKSdvgqWSSPPPQCIEESKV 288
Cdd:PHA02639 171 KTRVGFSCKSGFDLVGEKYSTCNINAT----WFPSIPTCVRNKPI 211
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 34-283 2.06e-12

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 66.99  E-value: 2.06e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118026913  34 CGPPPDIPNARPILGrHSKFAeqSKVAYSCNNGFKQVpdksnivvclenGQWSSHetfcekscdtperlsfaslkkeyfn 113
Cdd:PHA02927  86 CPSPRDIDNGQLDIG-GVDFG--SSITYSCNSGYQLI------------GESKSY------------------------- 125

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118026913 114 mnffpvgtiveyeCRPGFRKQpslsgkstcledLVWSPVAQFCKKKSCPNPKDLDNG-HINIPTGILFGSEINFSCNPGY 192
Cdd:PHA02927 126 -------------CELGSTGS------------MVWNPEAPICESVKCQSPPSISNGrHNGYEDFYTDGSVVTYSCNSGY 180

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118026913 193 RLVGITSILCTiignTVDWDDEfPVCTEIFCPDPPKINNGIMRGESDSYKYSQVVIYSCDKGFILFGNSTIYCTVSKSdv 272
Cdd:PHA02927 181 SLIGNSGVLCS----GGEWSDP-PTCQIVKCPHPTISNGYLSSGFKRSYSYNDNVDFKCKYGYKLSGSSSSTCSPGNT-- 253

                        250
                 ....*....|.
gi 118026913 273 gqWSSPPPQCI 283
Cdd:PHA02927 254 --WQPELPKCV 262
Sushi pfam00084
Sushi repeat (SCR repeat);
223-282 5.16e-12

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 60.59  E-value: 5.16e-12
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 118026913  223 CPDPPKINNGIMRGESDSYKYSQVVIYSCDKGFILFGNSTIYCTVSksdvGQWSSPPPQC 282
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCQED----GTWSPPFPEC 56
PHA02639 PHA02639
EEV host range protein; Provisional
 157-282 1.60e-11

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 64.69  E-value: 1.60e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118026913 157 KKKSCPNPKDLDNGHIN-IPTGILFGSEINFSCNPGYRLVGITSILCTIIGNTVDWDDEFPVCTEIFCPDPPKINNGIMR 235
Cdd:PHA02639  18 KSIYCDKPDDISNGFITeLMEKYEIGKLIEYTCNTDYALIGDRFRTCIKDKNNAIWSNKAPFCMLKECNDPPSIINGKIY 97

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 118026913 236 GESDSYKYSQVVIYSCD--KG--FILFGNSTIYCTVSKSdvgqWSSPPPQC 282
Cdd:PHA02639  98 NKREMYKVGDEIYYVCNehKGvqYSLVGNEKITCIQDKS----WKPDPPIC 144
PHA02831 PHA02831
EEV host range protein; Provisional
 123-286 2.13e-11

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 63.86  E-value: 2.13e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118026913 123 VEYECRPGFRKQPSLSGKSTcledlvWSPVAQFCKKKSCPNPKDLDNGHI-NIPTGILFGSEINFSCNPG----YRLVGI 197
Cdd:PHA02831  46 LEYKCNNNFDKVFVTCNNGS------WSTKNMCIGKRNCKDPVTILNGYIkNKKDQYSFGDSVTYACKVNklekYSIVGN 119

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118026913 198 TSILCTiignTVDWDDEFPVCTEIFCpDPPKINNGIMRGESDSYKYSQVVIYSCDKGFILFGNSTIYCTVSKSdvgqWSS 277
Cdd:PHA02831 120 ETVKCI----NKQWVPKYPVCKLIRC-KYPALQNGFLNVFEKKFYYGDIVNFKCKKGFILLGSSVSTCDINSI----WYP 190


                 ....*....
gi 118026913 278 PPPQCIEES 286
Cdd:PHA02831 191 GIPKCVKDK 199
PHA02817 PHA02817
EEV Host range protein; Provisional
 152-287 3.15e-10

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 59.57  E-value: 3.15e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118026913 152 VAQFCKKKSCPNPKDLDNGHI-NIPTGILFGSEINFSCNPG-----YRLVGITSILCTIIGNtvdWDDEFPVCTEIFCpD 225
Cdd:PHA02817  15 VYSLCDLNKCCYPPSIKNGYIyNKKTEYNIGSNVTFFCGNNtrgvrYTLVGEKNIICEKDGK---WNKEFPVCKIIRC-R 90

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 118026913 226 PPKINNGIMRGESDSYK--YSQVVIYSCDKGFILFGNSTIYCTVSKSdvgqWSSPPPQCIEESK 287
Cdd:PHA02817  91 FPALQNGFVNGIPDSKKfyYESEVSFSCKPGFVLIGTKYSVCGINSS----WIPKVPICSRDNI 150
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 34-93 5.01e-10

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 54.78  E-value: 5.01e-10
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 118026913  34 CGPPPDIPNARpILGRHSKFAEQSKVAYSCNNGFKQVPdkSNIVVCLENGQWSSHETFCE 93
Cdd:cd00033    1 CPPPPVPENGT-VTGSKGSYSYGSTVTYSCNEGYTLVG--SSTITCTENGGWSPPPPTCE 57
PHA02831 PHA02831
EEV host range protein; Provisional
 53-220 5.83e-10

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 59.62  E-value: 5.83e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118026913  53 FAEQSKVAYSCNNGFKQVpdksnIVVClENGQWSShETFC--EKSCDTPERLSFASLKKEyfnMNFFPVGTIVEYECRPG 130
Cdd:PHA02831  40 YEENENLEYKCNNNFDKV-----FVTC-NNGSWST-KNMCigKRNCKDPVTILNGYIKNK---KDQYSFGDSVTYACKVN 109

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118026913 131 FRKQPSLSGKST--CLeDLVWSPVAQFCKKKSCPNPKdLDNGHINI-PTGILFGSEINFSCNPGYRLVGITSILCTIigN 207
Cdd:PHA02831 110 KLEKYSIVGNETvkCI-NKQWVPKYPVCKLIRCKYPA-LQNGFLNVfEKKFYYGDIVNFKCKKGFILLGSSVSTCDI--N 185

                        170
                 ....*....|...
gi 118026913 208 TVdWDDEFPVCTE 220
Cdd:PHA02831 186 SI-WYPGIPKCVK 197
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 161-218 4.28e-09

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 52.14  E-value: 4.28e-09
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 118026913   161 CPNPKDLDNGHIN-IPTGILFGSEINFSCNPGYRLVGITSILCTiigNTVDWDDEFPVC 218
Cdd:smart00032   1 CPPPPDIENGTVTsSSGTYSYGDTVTYSCDPGYTLIGSSTITCL---ENGTWSPPPPTC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 161-218 4.67e-09

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 52.08  E-value: 4.67e-09
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 118026913 161 CPNPKDLDNGHINIPTGI-LFGSEINFSCNPGYRLVGITSILCTIIGNtvdWDDEFPVC 218
Cdd:cd00033    1 CPPPPVPENGTVTGSKGSySYGSTVTYSCNEGYTLVGSSTITCTENGG---WSPPPPTC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 34-92 1.90e-08

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 50.22  E-value: 1.90e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 118026913    34 CGPPPDIPNARpILGRHSKFAEQSKVAYSCNNGFKQVPdkSNIVVCLENGQWSSHETFC 92
Cdd:smart00032   1 CPPPPDIENGT-VTSSSGTYSYGDTVTYSCDPGYTLIG--SSTITCLENGTWSPPPPTC 56
PHA02954 PHA02954
EEV membrane glycoprotein; Provisional
 38-287 2.30e-08

EEV membrane glycoprotein; Provisional


Pssm-ID: 165263 [Multi-domain]  Cd Length: 317  Bit Score: 55.09  E-value: 2.30e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118026913  38 PDIPNARpILGRHSKFAEQSKVAYSCNNGFKQVPDKSnivVClENGQWSsHETFCEKSCDTPERLSfaslkkEYFNMNFF 117
Cdd:PHA02954  24 PTMNNAK-LTSTETSFNDKQKVTFTCDSGYYSLDPNA---VC-ETDKWK-YENPCKKMCTVSDYVS------ELYDKPLY 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118026913 118 PVGTIVEYECRPG---FRKQPSlsGKSTCLEDLVWSPVAQfCKkkscpnPKDLDNGHIN-IPTGILFGSEINFSCNPGYR 193
Cdd:PHA02954  92 EVNSTITLICKDEtkyFRCEEK--NGNTSWNDTVTCPNAE-CQ------PLQLEHGSCQpVKEKYSFGEHITINCDVGYE 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118026913 194 LVGITSILCTIIGNTVdwddeFPVCTEIFcpDPPKINNGIMRGEsdSYKYSQVVIYSCDKGFILFGNSTIYCTvsksdVG 273
Cdd:PHA02954 163 VIGASYISCTANSWNV-----IPSCQQKC--DIPSLSNGLISGS--TFSIGGVIHLSCKSGFTLTGSPSSTCI-----DG 228

                        250
                 ....*....|....
gi 118026913 274 QWSSPPPQCIEESK 287
Cdd:PHA02954 229 KWNPVLPICVRSNE 242
Sushi pfam00084
Sushi repeat (SCR repeat);
161-218 8.82e-08

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 48.65  E-value: 8.82e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 118026913  161 CPNPKDLDNGHINIPTGI-LFGSEINFSCNPGYRLVGITSILCTIIGNtvdWDDEFPVC 218
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEyNYGASVSYECDPGYRLVGSPTITCQEDGT---WSPPFPEC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
96-156 1.18e-07

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 48.26  E-value: 1.18e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 118026913   96 CDTPERLSFASLkkeYFNMNFFPVGTIVEYECRPGFRKQPSLsgKSTCLEDLVWSPVAQFC 156
Cdd:pfam00084   1 CPPPPDIPNGKV---SATKNEYNYGASVSYECDPGYRLVGSP--TITCQEDGTWSPPFPEC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
34-92 2.01e-07

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 47.49  E-value: 2.01e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 118026913   34 CGPPPDIPNARPIlGRHSKFAEQSKVAYSCNNGFKQVPdkSNIVVCLENGQWSSHETFC 92
Cdd:pfam00084   1 CPPPPDIPNGKVS-ATKNEYNYGASVSYECDPGYRLVG--SPTITCQEDGTWSPPFPEC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 96-157 8.59e-07

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 45.53  E-value: 8.59e-07
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 118026913  96 CDTPERLSFASLKkeyFNMNFFPVGTIVEYECRPGFRKQPslSGKSTCLEDLVWSPVAQFCK 157
Cdd:cd00033    1 CPPPPVPENGTVT---GSKGSYSYGSTVTYSCNEGYTLVG--SSTITCTENGGWSPPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 96-156 5.16e-05

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 40.59  E-value: 5.16e-05
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 118026913    96 CDTPERLSFASLKKEYFNmnfFPVGTIVEYECRPGFRKQPSLSgkSTCLEDLVWSPVAQFC 156
Cdd:smart00032   1 CPPPPDIENGTVTSSSGT---YSYGDTVTYSCDPGYTLIGSST--ITCLENGTWSPPPPTC 56
PHA02817 PHA02817
EEV Host range protein; Provisional
 108-220 3.26e-04

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 41.85  E-value: 3.26e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118026913 108 KKEYFNmnffpVGTIVEYECRPGFRKQP-SLSGKS--TCLEDLVWSPVAQFCKKKSCPNPKdLDNGHIN-IPTGILF--G 181
Cdd:PHA02817  38 KKTEYN-----IGSNVTFFCGNNTRGVRyTLVGEKniICEKDGKWNKEFPVCKIIRCRFPA-LQNGFVNgIPDSKKFyyE 111

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 118026913 182 SEINFSCNPGYRLVGITSILCTIignTVDWDDEFPVCTE 220
Cdd:PHA02817 112 SEVSFSCKPGFVLIGTKYSVCGI---NSSWIPKVPICSR 147
PHA02831 PHA02831
EEV host range protein; Provisional
 33-163 3.05e-03

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 39.21  E-value: 3.05e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118026913  33 DCGPPPDIPNARpILGRHSKFAEQSKVAYSCN-NGFKQVPDKSNIVVCLENGQWSSHETFCEKScdtpeRLSFASLKK-- 109
Cdd:PHA02831  77 NCKDPVTILNGY-IKNKKDQYSFGDSVTYACKvNKLEKYSIVGNETVKCINKQWVPKYPVCKLI-----RCKYPALQNgf 150

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 118026913 110 -EYFNMNFFpVGTIVEYECRPGFRKQPSLSgkSTCLEDLVWSPVAQFCKKKSCPN 163
Cdd:PHA02831 151 lNVFEKKFY-YGDIVNFKCKKGFILLGSSV--STCDINSIWYPGIPKCVKDKVHN 202
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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