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Conserved domains on  [gi|126517489|ref|NP_031676|]
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T-cell surface glycoprotein CD5 precursor [Mus musculus]

Protein Classification

SR and SRCR domain-containing protein( domain architecture ID 12193634)

SR and SRCR domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SR smart00202
Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR ...
 34-133 5.38e-17

Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR domains that contain 6 conserved cysteines. May bind bacterial antigens in the protein MARCO.


:

Pssm-ID: 214555 [Multi-domain]  Cd Length: 101  Bit Score: 76.23  E-value: 5.38e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126517489    34 VMLSGSNSKCQGQVEIQMENKWKTVCSSSWrlsqdhskNAQQASAVCKQLRCGDPLALGP---FPSLNRPQ--NQVFCQG 108
Cdd:smart00202   1 VRLVGGGSPCEGRVEVYHNGQWGTVCDDGW--------DLRDANVVCRQLGFGGAVSASGsayFGPGSGPIwlDNVRCSG 72

                           90       100
                   ....*....|....*....|....*....
gi 126517489   109 SPWSISNC-NNTSSQDQCL---PLSLICL 133
Cdd:smart00202  73 TEASLSDCpHSGWGSHNCShgeDAGVVCS 101
SR smart00202
Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR ...
 277-367 1.79e-05

Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR domains that contain 6 conserved cysteines. May bind bacterial antigens in the protein MARCO.


:

Pssm-ID: 214555 [Multi-domain]  Cd Length: 101  Bit Score: 43.48  E-value: 1.79e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126517489   277 RLVGGSSVCEGIAEVRQRSQWEALCDSSaargrgrWEE-----LCREQQCGDLISFHT--VDADKTSP----GFLCA-QE 344
Cdd:smart00202   2 RLVGGGSPCEGRVEVYHNGQWGTVCDDG-------WDLrdanvVCRQLGFGGAVSASGsaYFGPGSGPiwldNVRCSgTE 74

                           90       100
                   ....*....|....*....|....*..
gi 126517489   345 K-LSQCYHLQKKKH-CNKR--VFVTCQ 367
Cdd:smart00202  75 AsLSDCPHSGWGSHnCSHGedAGVVCS 101
SRCR super family cl27545
Scavenger receptor cysteine-rich domain; These domains are disulphide rich extracellular ...
 167-222 1.81e-03

Scavenger receptor cysteine-rich domain; These domains are disulphide rich extracellular domains. These domains are found in several extracellular receptors and may be involved in protein-protein interactions.


The actual alignment was detected with superfamily member pfam00530:

Pssm-ID: 459844  Cd Length: 98  Bit Score: 37.74  E-value: 1.81e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 126517489  167 GLRCTGVVE-FYNGSWGgTILykakDRPLGL--GNLICKSLQCGSFLTHLSGTEAAGTP 222
Cdd:pfam00530   2 SSPCEGRVEvYHNGSWG-TVC----DDGWDLrdAHVVCRQLGCGGAVSAPSGCSYFGPG 55
 
Name Accession Description Interval E-value
SR smart00202
Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR ...
 34-133 5.38e-17

Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR domains that contain 6 conserved cysteines. May bind bacterial antigens in the protein MARCO.


Pssm-ID: 214555 [Multi-domain]  Cd Length: 101  Bit Score: 76.23  E-value: 5.38e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126517489    34 VMLSGSNSKCQGQVEIQMENKWKTVCSSSWrlsqdhskNAQQASAVCKQLRCGDPLALGP---FPSLNRPQ--NQVFCQG 108
Cdd:smart00202   1 VRLVGGGSPCEGRVEVYHNGQWGTVCDDGW--------DLRDANVVCRQLGFGGAVSASGsayFGPGSGPIwlDNVRCSG 72

                           90       100
                   ....*....|....*....|....*....
gi 126517489   109 SPWSISNC-NNTSSQDQCL---PLSLICL 133
Cdd:smart00202  73 TEASLSDCpHSGWGSHNCShgeDAGVVCS 101
SRCR pfam00530
Scavenger receptor cysteine-rich domain; These domains are disulphide rich extracellular ...
 39-125 1.38e-08

Scavenger receptor cysteine-rich domain; These domains are disulphide rich extracellular domains. These domains are found in several extracellular receptors and may be involved in protein-protein interactions.


Pssm-ID: 459844  Cd Length: 98  Bit Score: 52.38  E-value: 1.38e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126517489   39 SNSKCQGQVEIQMENKWKTVCSSSWRLsqdhsknaQQASAVCKQLRCGDPLALG-----PFPSLNRP--QNQVFCQGSPW 111
Cdd:pfam00530   1 GSSPCEGRVEVYHNGSWGTVCDDGWDL--------RDAHVVCRQLGCGGAVSAPsgcsyFGPGSTGPiwLDDVRCSGNET 72

                          90
                  ....*....|....*
gi 126517489  112 SISNCNNT-SSQDQC 125
Cdd:pfam00530  73 SLWQCPHRpWGNHNC 87
SR smart00202
Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR ...
 277-367 1.79e-05

Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR domains that contain 6 conserved cysteines. May bind bacterial antigens in the protein MARCO.


Pssm-ID: 214555 [Multi-domain]  Cd Length: 101  Bit Score: 43.48  E-value: 1.79e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126517489   277 RLVGGSSVCEGIAEVRQRSQWEALCDSSaargrgrWEE-----LCREQQCGDLISFHT--VDADKTSP----GFLCA-QE 344
Cdd:smart00202   2 RLVGGGSPCEGRVEVYHNGQWGTVCDDG-------WDLrdanvVCRQLGFGGAVSASGsaYFGPGSGPiwldNVRCSgTE 74

                           90       100
                   ....*....|....*....|....*..
gi 126517489   345 K-LSQCYHLQKKKH-CNKR--VFVTCQ 367
Cdd:smart00202  75 AsLSDCPHSGWGSHnCSHGedAGVVCS 101
SRCR pfam00530
Scavenger receptor cysteine-rich domain; These domains are disulphide rich extracellular ...
 167-222 1.81e-03

Scavenger receptor cysteine-rich domain; These domains are disulphide rich extracellular domains. These domains are found in several extracellular receptors and may be involved in protein-protein interactions.


Pssm-ID: 459844  Cd Length: 98  Bit Score: 37.74  E-value: 1.81e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 126517489  167 GLRCTGVVE-FYNGSWGgTILykakDRPLGL--GNLICKSLQCGSFLTHLSGTEAAGTP 222
Cdd:pfam00530   2 SSPCEGRVEvYHNGSWG-TVC----DDGWDLrdAHVVCRQLGCGGAVSAPSGCSYFGPG 55
 
Name Accession Description Interval E-value
SR smart00202
Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR ...
 34-133 5.38e-17

Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR domains that contain 6 conserved cysteines. May bind bacterial antigens in the protein MARCO.


Pssm-ID: 214555 [Multi-domain]  Cd Length: 101  Bit Score: 76.23  E-value: 5.38e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126517489    34 VMLSGSNSKCQGQVEIQMENKWKTVCSSSWrlsqdhskNAQQASAVCKQLRCGDPLALGP---FPSLNRPQ--NQVFCQG 108
Cdd:smart00202   1 VRLVGGGSPCEGRVEVYHNGQWGTVCDDGW--------DLRDANVVCRQLGFGGAVSASGsayFGPGSGPIwlDNVRCSG 72

                           90       100
                   ....*....|....*....|....*....
gi 126517489   109 SPWSISNC-NNTSSQDQCL---PLSLICL 133
Cdd:smart00202  73 TEASLSDCpHSGWGSHNCShgeDAGVVCS 101
SRCR pfam00530
Scavenger receptor cysteine-rich domain; These domains are disulphide rich extracellular ...
 39-125 1.38e-08

Scavenger receptor cysteine-rich domain; These domains are disulphide rich extracellular domains. These domains are found in several extracellular receptors and may be involved in protein-protein interactions.


Pssm-ID: 459844  Cd Length: 98  Bit Score: 52.38  E-value: 1.38e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126517489   39 SNSKCQGQVEIQMENKWKTVCSSSWRLsqdhsknaQQASAVCKQLRCGDPLALG-----PFPSLNRP--QNQVFCQGSPW 111
Cdd:pfam00530   1 GSSPCEGRVEVYHNGSWGTVCDDGWDL--------RDAHVVCRQLGCGGAVSAPsgcsyFGPGSTGPiwLDDVRCSGNET 72

                          90
                  ....*....|....*
gi 126517489  112 SISNCNNT-SSQDQC 125
Cdd:pfam00530  73 SLWQCPHRpWGNHNC 87
SR smart00202
Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR ...
 277-367 1.79e-05

Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR domains that contain 6 conserved cysteines. May bind bacterial antigens in the protein MARCO.


Pssm-ID: 214555 [Multi-domain]  Cd Length: 101  Bit Score: 43.48  E-value: 1.79e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126517489   277 RLVGGSSVCEGIAEVRQRSQWEALCDSSaargrgrWEE-----LCREQQCGDLISFHT--VDADKTSP----GFLCA-QE 344
Cdd:smart00202   2 RLVGGGSPCEGRVEVYHNGQWGTVCDDG-------WDLrdanvVCRQLGFGGAVSASGsaYFGPGSGPiwldNVRCSgTE 74

                           90       100
                   ....*....|....*....|....*..
gi 126517489   345 K-LSQCYHLQKKKH-CNKR--VFVTCQ 367
Cdd:smart00202  75 AsLSDCPHSGWGSHnCSHGedAGVVCS 101
SRCR pfam00530
Scavenger receptor cysteine-rich domain; These domains are disulphide rich extracellular ...
 167-222 1.81e-03

Scavenger receptor cysteine-rich domain; These domains are disulphide rich extracellular domains. These domains are found in several extracellular receptors and may be involved in protein-protein interactions.


Pssm-ID: 459844  Cd Length: 98  Bit Score: 37.74  E-value: 1.81e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 126517489  167 GLRCTGVVE-FYNGSWGgTILykakDRPLGL--GNLICKSLQCGSFLTHLSGTEAAGTP 222
Cdd:pfam00530   2 SSPCEGRVEvYHNGSWG-TVC----DDGWDLrdAHVVCRQLGCGGAVSAPSGCSYFGPG 55
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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