NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|398364931|ref|NP_012575|]
View 

Urb2p [Saccharomyces cerevisiae S288C]

Protein Classification

Urb2 domain-containing protein( domain architecture ID 10564512)

Urb2 domain-containing protein similar to Saccharomyces cerevisiae nucleolar pre-ribosomal-associated protein 2 (Npa2), also called unhealthy ribosome biogenesis protein 2 (Urb2), that is required for 27S pre-rRNA processing, and has an early role during 60S ribosomal subunit assembly

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

Name Accession Description Interval E-value
Urb2 pfam10441
Urb2/Npa2 family; This family includes the Urb2 protein from yeast that are involved in ...
964-1174 1.43e-61

Urb2/Npa2 family; This family includes the Urb2 protein from yeast that are involved in ribosome biogenesis.


:

Pssm-ID: 431289  Cd Length: 213  Bit Score: 209.04  E-value: 1.43e-61
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364931   964 LLLFNAIKEFLVSKPWLFSQYCIEMLLPFCLKTLAFIVNHESTDEiNEGFINIIEVIDHMLLVHRFKFSNRHHLFNSVLC 1043
Cdd:pfam10441    1 LLALEVLDTLLSSKPWLFSQYDIEQLLSLVSTLLSPLLSLESSSA-DEIFIALCSLLSTILRHHRDKLSGRFHLLLSVLQ 79
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364931  1044 QILEIIAIHDGT-------LCANSADAVARLITNYCEPYNVSNaqngQKNNLSSKISLIKQSIRKNVLVVLTKYIQLSIT 1116
Cdd:pfam10441   80 ALLRCLFTWLDTgtskplpLSAKHAKALSRLLTNLCEPTVSSV----SKSSLTSATKSAKKSLGKHAPYLLAAYIKLQLG 155
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 398364931  1117 TQFSLNIKKSLQPGIHAIFDILSQNELNQLNAFLDTPGKQYFKALYLQYKKVGKWRED 1174
Cdd:pfam10441  156 SGLPPEVREALTPGLYAIFDVLSQEELQLLNAALDASGRAVFKTLYKDYKKFGKWKGK 213
 
Name Accession Description Interval E-value
Urb2 pfam10441
Urb2/Npa2 family; This family includes the Urb2 protein from yeast that are involved in ...
964-1174 1.43e-61

Urb2/Npa2 family; This family includes the Urb2 protein from yeast that are involved in ribosome biogenesis.


Pssm-ID: 431289  Cd Length: 213  Bit Score: 209.04  E-value: 1.43e-61
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364931   964 LLLFNAIKEFLVSKPWLFSQYCIEMLLPFCLKTLAFIVNHESTDEiNEGFINIIEVIDHMLLVHRFKFSNRHHLFNSVLC 1043
Cdd:pfam10441    1 LLALEVLDTLLSSKPWLFSQYDIEQLLSLVSTLLSPLLSLESSSA-DEIFIALCSLLSTILRHHRDKLSGRFHLLLSVLQ 79
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364931  1044 QILEIIAIHDGT-------LCANSADAVARLITNYCEPYNVSNaqngQKNNLSSKISLIKQSIRKNVLVVLTKYIQLSIT 1116
Cdd:pfam10441   80 ALLRCLFTWLDTgtskplpLSAKHAKALSRLLTNLCEPTVSSV----SKSSLTSATKSAKKSLGKHAPYLLAAYIKLQLG 155
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 398364931  1117 TQFSLNIKKSLQPGIHAIFDILSQNELNQLNAFLDTPGKQYFKALYLQYKKVGKWRED 1174
Cdd:pfam10441  156 SGLPPEVREALTPGLYAIFDVLSQEELQLLNAALDASGRAVFKTLYKDYKKFGKWKGK 213
 
Name Accession Description Interval E-value
Urb2 pfam10441
Urb2/Npa2 family; This family includes the Urb2 protein from yeast that are involved in ...
964-1174 1.43e-61

Urb2/Npa2 family; This family includes the Urb2 protein from yeast that are involved in ribosome biogenesis.


Pssm-ID: 431289  Cd Length: 213  Bit Score: 209.04  E-value: 1.43e-61
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364931   964 LLLFNAIKEFLVSKPWLFSQYCIEMLLPFCLKTLAFIVNHESTDEiNEGFINIIEVIDHMLLVHRFKFSNRHHLFNSVLC 1043
Cdd:pfam10441    1 LLALEVLDTLLSSKPWLFSQYDIEQLLSLVSTLLSPLLSLESSSA-DEIFIALCSLLSTILRHHRDKLSGRFHLLLSVLQ 79
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364931  1044 QILEIIAIHDGT-------LCANSADAVARLITNYCEPYNVSNaqngQKNNLSSKISLIKQSIRKNVLVVLTKYIQLSIT 1116
Cdd:pfam10441   80 ALLRCLFTWLDTgtskplpLSAKHAKALSRLLTNLCEPTVSSV----SKSSLTSATKSAKKSLGKHAPYLLAAYIKLQLG 155
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 398364931  1117 TQFSLNIKKSLQPGIHAIFDILSQNELNQLNAFLDTPGKQYFKALYLQYKKVGKWRED 1174
Cdd:pfam10441  156 SGLPPEVREALTPGLYAIFDVLSQEELQLLNAALDASGRAVFKTLYKDYKKFGKWKGK 213
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH