|
Name |
Accession |
Description |
Interval |
E-value |
| cysta_beta_ly_E |
TIGR01329 |
cystathionine beta-lyase, eukaryotic; This model represents cystathionine beta-lyase ... |
6-409 |
0e+00 |
|
cystathionine beta-lyase, eukaryotic; This model represents cystathionine beta-lyase (alternate name: beta-cystathionase), one of several pyridoxal-dependent enzymes of cysteine, methionine, and homocysteine metabolism. This enzyme is involved in the biosynthesis of Met from Cys.
Pssm-ID: 273557 [Multi-domain] Cd Length: 378 Bit Score: 663.45 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 6 LDTVVVNTGSQNDQHSASVPPVYLSTTFKVDLNNEDAQnYDYSRSGNPTRSVLQHQIGKLYRVpqENVLAVSSGMTALDV 85
Cdd:TIGR01329 1 LSTLLVNTDNKNDPYDASSMPIYQTATFKQPLAIENGP-YDYTRSGNPTRTALESLLAKLDKA--DRAFAFSSGMAALDV 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 86 ILRglvLLNGTDnhtpTIIAGDDLYGGTQRLLNFFKQQSHAVSVHVDTSDFEKFKTVFQslDKVDCVLLESPTNPLCKVV 165
Cdd:TIGR01329 78 ITR---LLNNGD----EIIAGDDLYGGTDRLLTQVVPRSGVVVVHVDTTDLDKVKAALG--PKTKLVLLESPTNPLQKIV 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 166 DIPRILRFVKCISpdTTVVVDNTMMSGLNCNPLQLnpGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINSTG 245
Cdd:TIGR01329 149 DIRKISEMAHAQN--ALVVVDNTMMSPLLCNPLEL--GADIVYHSATKFLAGHSDVMAGVLAVKGEEIAKKVYFLQNSTG 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 246 AGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLEnscgfkpTRTNKAtKTRFVGLRSNPDFKLHKSFNNGPGAVLSF 325
Cdd:TIGR01329 225 SGLAPFDCWLLLRGIKTLAIRIEKQQENARAIAMFLS-------THPRVK-KVRYAGLPSHPGFHLHFSQAKGAGSVLSF 296
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 326 ETGSFEHSKRLVSSKKLsiWAVTVSFGCVNSLLSMPCKMSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMV 405
Cdd:TIGR01329 297 ETGSVALSKRLVEATKL--FSITVSFGSVNSLISMPCFMSHASIPAEVREERGLPEDLVRLSVGIEDVDDLISDLDIAFV 374
|
....
gi 398364309 406 DADI 409
Cdd:TIGR01329 375 TAPA 378
|
|
| Cys_Met_Meta_PP |
pfam01053 |
Cys/Met metabolism PLP-dependent enzyme; This family includes enzymes involved in cysteine and ... |
7-404 |
1.48e-173 |
|
Cys/Met metabolism PLP-dependent enzyme; This family includes enzymes involved in cysteine and methionine metabolism. The following are members: Cystathionine gamma-lyase, Cystathionine gamma-synthase, Cystathionine beta-lyase, Methionine gamma-lyase, OAH/OAS sulfhydrylase, O-succinylhomoserine sulfhydrylase All of these members participate is slightly different reactions. All these enzymes use PLP (pyridoxal-5'-phosphate) as a cofactor.
Pssm-ID: 395837 [Multi-domain] Cd Length: 376 Bit Score: 491.75 E-value: 1.48e-173
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 7 DTVVVNTGSQND-QHSASVPPVYLSTTFKVDLNNEDAQnYDYSRSGNPTRSVLQHQIGKLYRVpqENVLAVSSGMTALDV 85
Cdd:pfam01053 1 DTLAVHAGQRPDpQTGAVSVPIYLTSTYVFDFAGEEGG-YDYSRSGNPTRDVLEERIAALEGG--AAALAFSSGMAAITA 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 86 ILRGLvLLNGTDnhtptIIAGDDLYGGTQRLLNFFKQQSHAVSVHVDTSDFEKFKTVFQslDKVDCVLLESPTNPLCKVV 165
Cdd:pfam01053 78 AILAL-LKAGDH-----IVATDDLYGGTYRLFNKVLPRFGIEVTFVDTSDPEDLEAAIK--PNTKAVYLETPTNPLLKVV 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 166 DIPRILRFVKCISpdTTVVVDNTMMSGLNCNPLQLnpGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINSTG 245
Cdd:pfam01053 150 DIEAIAKLAKKHG--ILVVVDNTFASPYLQRPLDL--GADIVVHSATKYIGGHSDVVGGVIVVNGEELGKELYFLQNATG 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 246 AGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENScgfkPtrtnKATKTRFVGLRSNPDFKLHKSFNNGPGAVLSF 325
Cdd:pfam01053 226 AVLSPFDAWLLLRGLKTLGLRMEQHQENAQKVAEFLESH----P----KVEKVYYPGLPSHPGHELAKRQMKGFGGMLSF 297
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 326 ETGSF-EHSKRLVssKKLSIWAVTVSFGCVNSLLSMPCKMSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAM 404
Cdd:pfam01053 298 ELKGGlEAAKKFL--DNLKLFSLAVSLGGVESLISHPATMTHASIPPEEREAAGITDDLIRLSVGIEDVDDLIADLKQAL 375
|
|
| MetC |
COG0626 |
Cystathionine beta-lyase/cystathionine gamma-synthase [Amino acid transport and metabolism]; ... |
4-404 |
3.97e-114 |
|
Cystathionine beta-lyase/cystathionine gamma-synthase [Amino acid transport and metabolism]; Cystathionine beta-lyase/cystathionine gamma-synthase is part of the Pathway/BioSystem: Methionine biosynthesis
Pssm-ID: 440391 [Multi-domain] Cd Length: 389 Bit Score: 340.87 E-value: 3.97e-114
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 4 KRLDTVVVNTGSQNDQHSASV-PPVYLSTTF-------KVDLNNEDAQNYDYSRSGNPTRSVLQHQIGKLyrvpqEN--- 72
Cdd:COG0626 1 MGPATRAVHAGRDPDPQTGAVsPPIYLTSTFvfpsaeaLAARFAGEEGGYIYSRYGNPTRRALEEALAAL-----EGgea 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 73 VLAVSSGMTALDVILrgLVLLNGTDnhtpTIIAGDDLYGGTQRLLN-FFKQQSHAVSVhVDTSDFEKFKTVFQslDKVDC 151
Cdd:COG0626 76 ALAFASGMAAISAVL--LALLKAGD----HVVASDDLYGGTRRLLDkVLARFGIEVTF-VDPTDLAAVEAAIR--PNTKL 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 152 VLLESPTNPLCKVVDIPRILRFVKciSPDTTVVVDNTMMSGLNCNPLQLnpGCDVVYESATKYLNGHHDLMGGVIISKTP 231
Cdd:COG0626 147 VFLETPSNPTLEVVDIAAIAAIAH--AAGALLVVDNTFATPLLQRPLEL--GADIVVHSATKYLGGHSDVLGGAVVGRDE 222
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 232 EIASKLYFVINSTGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENScgfkPtrtnKATKTRFVGLRSNPDFKL 311
Cdd:COG0626 223 ELAERLRFLQNALGAVLSPFDAWLLLRGLKTLALRMERHCENALAVAEWLEAH----P----AVARVYYPGLPSHPGHEL 294
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 312 HKSFNNGPGAVLSFE-TGSFEHSKRLVSSkkLSIWAVTVSFGCVNSLLSMPCKMSHASIDPELRKERDFPEDLVRLCCGI 390
Cdd:COG0626 295 AKRQMSGFGGMLSFElKGGREAARRFLDA--LKLFTLAVSLGGVESLITHPATMTHRSLPPEERAALGITDGLVRLSVGL 372
|
410
....*....|....
gi 398364309 391 ENIVDLKKDLLAAM 404
Cdd:COG0626 373 EDVDDLIADLEQAL 386
|
|
| CGS_like |
cd00614 |
CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed ... |
24-403 |
2.95e-106 |
|
CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of antimicrobials and herbicides. This subgroup also includes cystathionine gamma-lyases (CGL), O-acetylhomoserine sulfhydrylases and O-acetylhomoserine thiol lyases. CGL's are very similar to CGS's. Members of this group are widely distributed among all three forms of life.
Pssm-ID: 99738 [Multi-domain] Cd Length: 369 Bit Score: 319.92 E-value: 2.95e-106
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 24 VPPVYLSTTFKVD-------LNNEDAQNYDYSRSGNPTRSVLQHQIGKLYRvpQENVLAVSSGMTALDVILrgLVLLNGT 96
Cdd:cd00614 4 APPIYQTSTFVFPspaeaadLFALREGGYIYSRIGNPTVDALEKKLAALEG--GEAALAFSSGMAAISTVL--LALLKAG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 97 DNhtptIIAGDDLYGGTQRLLNFFKQQsHAVSVH-VDTSDFEKFKTVFQslDKVDCVLLESPTNPLCKVVDIPRILRFVK 175
Cdd:cd00614 80 DH----VVASDDLYGGTYRLFERLLPK-LGIEVTfVDPDDPEALEAAIK--PETKLVYVESPTNPTLKVVDIEAIAELAH 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 176 ciSPDTTVVVDNTMMSGLNCNPLQLnpGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINSTGAGLSPMDSWL 255
Cdd:cd00614 153 --EHGALLVVDNTFATPYLQRPLEL--GADIVVHSATKYIGGHSDVIAGVVVGSGEALIQRLRFLRLALGTILSPFDAWL 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 256 LVRGLKTLGVRLYQQQRNAMILAHWLENscgfKPtrtnKATKTRFVGLRSNPDFKLHKSFNNGPGAVLSFE-TGSFEHSK 334
Cdd:cd00614 229 LLRGLKTLPLRMERHSENALKVAEFLEK----HP----KVERVYYPGLPSHPQHELAKKQMSGYGGVFSFElKGGLEAAK 300
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 398364309 335 RLVSSKKLSIWAvtVSFGCVNSLLSMPCKMSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAA 403
Cdd:cd00614 301 KFLNALKLFSLA--VSLGGVESLVEHPASMTHSQLPPEERAAAGITPGLVRLSVGIEDVEDLIADLEQA 367
|
|
| PLN02509 |
PLN02509 |
cystathionine beta-lyase |
1-400 |
1.81e-95 |
|
cystathionine beta-lyase
Pssm-ID: 178125 [Multi-domain] Cd Length: 464 Bit Score: 295.78 E-value: 1.81e-95
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 1 MPIKR---LDTVVVNTGSQNDQHSASVPPVYLSTTFKVDLNNEDAQnYDYSRSGNPTRSVLQHQIGKLYRVpqENVLAVS 77
Cdd:PLN02509 79 MNIKEeasVSTLLVNLDNKFDPFDAMSTPLYQTATFKQPSAIENGP-YDYTRSGNPTRDALESLLAKLDKA--DRAFCFT 155
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 78 SGMTALDVILRglVLLNGTDnhtptIIAGDDLYGGTQRLLNFFKQQSHAVSVHVDTSDFEKFKTVFQSLDKVdcVLLESP 157
Cdd:PLN02509 156 SGMAALSAVTH--LIKNGEE-----IVAGDDVYGGSDRLLSQVVPRSGVVVKRVNTTNLDEVAAAIGPQTKL--VWLESP 226
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 158 TNPLCKVVDIPRILRFVKciSPDTTVVVDNTMMSGLNCNPLQLnpGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKL 237
Cdd:PLN02509 227 TNPRQQISDIRKIAEMAH--AQGALVLVDNSIMSPVLSRPLEL--GADIVMHSATKFIAGHSDVMAGVLAVKGEKLAKEV 302
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 238 YFVINSTGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENscgfKPtrtnKATKTRFVGLRSNPDFKLHKSFNN 317
Cdd:PLN02509 303 YFLQNSEGSGLAPFDCWLCLRGIKTMALRIEKQQENARKIAMYLSS----HP----RVKKVYYAGLPDHPGHHLHFSQAK 374
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 318 GPGAVLSFETGSFEHSKRLVSSKKLsiWAVTVSFGCVNSLLSMPCKMSHASIDPELRKERDFPEDLVRLCCGIENIVDLK 397
Cdd:PLN02509 375 GAGSVFSFITGSVALSKHLVETTKY--FSIAVSFGSVKSLISMPCFMSHASIPAEVREARGLTEDLVRISAGIEDVDDLI 452
|
...
gi 398364309 398 KDL 400
Cdd:PLN02509 453 SDL 455
|
|
| O_succ_thio_ly |
TIGR02080 |
O-succinylhomoserine (thiol)-lyase; This family consists of O-succinylhomoserine (thiol)-lyase, ... |
4-404 |
3.59e-94 |
|
O-succinylhomoserine (thiol)-lyase; This family consists of O-succinylhomoserine (thiol)-lyase, one of three different enzymes designated cystathionine gamma-synthase and involved in methionine biosynthesis. In all three cases, sulfur is added by transsulfuration from Cys to yield cystathionine rather than by a sulfhydrylation step that uses H2S directly and bypasses cystathionine. [Amino acid biosynthesis, Aspartate family]
Pssm-ID: 131135 Cd Length: 382 Bit Score: 289.78 E-value: 3.59e-94
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 4 KRLDTVVVNTGSQND-QHSASVPPVYLSTTFKVDLNNEdAQNYDYSRSGNPTRSVLQHQIGKLYRvpQENVLAVSSGMTA 82
Cdd:TIGR02080 2 RKQATIAVRSGLNSDtQYGCVVPPIYLSTTYNFTGFNE-PRAYDYSRSGNPTRDLLQQALAELEG--GAGAVVTNTGMSA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 83 LDVILrgLVLLNGTDnhtpTIIAGDDLYGGTQRLLNFFKQQSHAVSVHVDTSDFEKFKtvfQSL-DKVDCVLLESPTNPL 161
Cdd:TIGR02080 79 IHLVT--TALLGPDD----LLVAPHDCYGGTYRLLNALAKKGCFRVLFVDQGDEQALR---AALaQKPKLVLIETPSNPL 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 162 CKVVDIPRILRFVKciSPDTTVVVDNTMMSGLNCNPLQLnpGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVI 241
Cdd:TIGR02080 150 LRVVDIAKICHLAK--AVGAVVVVDNTFLSPALQNPLAL--GADLVLHSCTKYLNGHSDVIAGAVIAKDPQVAEELAWWA 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 242 NSTGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKptrtnkatKTRFVGLRSNPDFKLHKSFNNGPGA 321
Cdd:TIGR02080 226 NNLGVTGGAFDSYLTLRGLRTLVARMRLQQRNAQAIVEYLQTQPLVK--------KIYYPGLPDHPGHEIAARQQKGFGA 297
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 322 VLSFE-TGSFEHSKRLVssKKLSIWAVTVSFGCVNSLLSMPCKMSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDL 400
Cdd:TIGR02080 298 MLSFElKGGEQTVRRFL--GGLSLFTLAESLGGVESLIAHPATMTHAAMGPEARAEAGISDTLLRLSVGLEDADDLIADL 375
|
....
gi 398364309 401 LAAM 404
Cdd:TIGR02080 376 EQGL 379
|
|
| PRK07671 |
PRK07671 |
bifunctional cystathionine gamma-lyase/homocysteine desulfhydrase; |
5-404 |
7.03e-85 |
|
bifunctional cystathionine gamma-lyase/homocysteine desulfhydrase;
Pssm-ID: 181076 [Multi-domain] Cd Length: 377 Bit Score: 265.43 E-value: 7.03e-85
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 5 RLDTVVVNTGSQNDQHSASV-PPVYLSTTFKVDLNNEDaQNYDYSRSGNPTRSVLQHQIGKLYRvpQENVLAVSSGMTAL 83
Cdd:PRK07671 2 RAKTKLIHGGIIGDPSTGAVsVPIYQVSTYKQEAVGKH-QGYEYSRTGNPTRAALEELIAVLEG--GHAGFAFGSGMAAI 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 84 DVILrglVLLNGTDNhtptIIAGDDLYGGTQRLLNFFKQQSHAVSVHVDTSDFEKFKTVFQSLDKVdcVLLESPTNPLCK 163
Cdd:PRK07671 79 TAVM---MLFSSGDH----VILTDDVYGGTYRVMTKVLNRFGIEHTFVDTSNLEEVEEAIRPNTKA--IYVETPTNPLLK 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 164 VVDIPRILRFVKciSPDTTVVVDNTMMSGLNCNPLQLnpGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINS 243
Cdd:PRK07671 150 ITDIKKISTIAK--EKGLLTIVDNTFMTPYWQSPISL--GADIVLHSATKYLGGHSDVVAGLVVVNSPELAEDLHFVQNS 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 244 TGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENScgfkptrtNKATKTRFVGLRSNPDFKLHKSFNNGPGAVL 323
Cdd:PRK07671 226 TGGILGPQDSWLLLRGLKTLGIRMEEHETNSRAIAEFLNNH--------PAVNKVYYPGLPSHPNHELAKEQANGFGGMI 297
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 324 SFETGSFEHSKRLVSskKLSIWAVTVSFGCVNSLLSMPCKMSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAA 403
Cdd:PRK07671 298 SFDVGSEETANKVLE--RLQYFTLAESLGAVESLISIPSQMTHASIPADRRKELGITDGLIRISVGIEDGEDLIEDLAQA 375
|
.
gi 398364309 404 M 404
Cdd:PRK07671 376 L 376
|
|
| PRK08064 |
PRK08064 |
cystathionine beta-lyase MetC; |
6-404 |
1.58e-81 |
|
cystathionine beta-lyase MetC;
Pssm-ID: 236146 [Multi-domain] Cd Length: 390 Bit Score: 257.39 E-value: 1.58e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 6 LDTVVVNTGSQNDQHSASVP-PVYLSTTFKvDLNNEDAQNYDYSRSGNPTRSVLQHQIGKLyrvpqE---NVLAVSSGMT 81
Cdd:PRK08064 7 IDTLLLHNQYKHDKQTGAVNvPIYHASTFH-QFDFDTFGKYDYSRSGNPTREALEDIIAEL-----EggtKGFAFASGMA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 82 AldvILRGLVLLNGTDNhtptIIAGDDLYGGTQRLLNFFKQQSHAVSVHVDTSDFEKFKTVFQSLDKVdcVLLESPTNPL 161
Cdd:PRK08064 81 A---ISTAFLLLSKGDH----VLISEDVYGGTYRMITEVLSRFGIEHTFVDMTNLEEVAQNIKPNTKL--FYVETPSNPL 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 162 CKVVDIPRILRFVKCISPDTtvVVDNTMMSGLNCNPLQLnpGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVI 241
Cdd:PRK08064 152 LKVTDIRGVVKLAKAIGCLT--FVDNTFLTPLLQKPLDL--GADVVLHSATKFLAGHSDVLAGLAVVKDEELAQKLYFLQ 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 242 NSTGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENScgfkptrtNKATKTRFVGLRSNPDFKLHKSFNNGPGA 321
Cdd:PRK08064 228 NSFGAVLGVQDCWLVLRGLKTLHVRLEHSSETANKIALYLQEH--------PKVQNVYYPGLQTHLGFDIQQSQATSAGA 299
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 322 VLSFETGSFEHSKRLVSSKKLSIWAvtVSFGCVNSLLSMPCKMSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLL 401
Cdd:PRK08064 300 VLSFTLQSEEAVRQFVSHVKLPVFA--VSLGAVESILSYPAKMSHAAMPKEERDERGITDGLLRLSVGLENVDDLIADFE 377
|
...
gi 398364309 402 AAM 404
Cdd:PRK08064 378 QAL 380
|
|
| PRK07811 |
PRK07811 |
cystathionine gamma-synthase; Provisional |
6-404 |
1.79e-78 |
|
cystathionine gamma-synthase; Provisional
Pssm-ID: 236104 [Multi-domain] Cd Length: 388 Bit Score: 249.18 E-value: 1.79e-78
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 6 LDTVVVNTGSQNDQHSASV-PPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIGKLYRvpQENVLAVSSGMTALD 84
Cdd:PRK07811 13 FATRAIHAGYEPDPATGAVnPPIYASSTFAQDGVGGLRGGYEYARTGNPTRTALEEQLAALEG--GAYGRAFSSGMAATD 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 85 VILRglVLLNGTDNhtptIIAGDDLYGGTQRLLN-FFKQQSHAVSVhVDTSDFEKFKTVFQSLDKVdcVLLESPTNPLCK 163
Cdd:PRK07811 91 CLLR--AVLRPGDH----IVIPNDAYGGTFRLIDkVFTRWGVEYTP-VDLSDLDAVRAAITPRTKL--IWVETPTNPLLS 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 164 VVDIPRILRFVKciSPDTTVVVDNTMMSGLNCNPLQLnpGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINS 243
Cdd:PRK07811 162 ITDIAALAELAH--DAGAKVVVDNTFASPYLQQPLAL--GADVVVHSTTKYIGGHSDVVGGALVTNDEELDEAFAFLQNG 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 244 TGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLEnscgfkptRTNKATKTRFVGLRSNPDFKLHKSFNNGPGAVL 323
Cdd:PRK07811 238 AGAVPGPFDAYLTLRGLKTLAVRMDRHSENAEAVAEFLA--------GHPEVSTVLYPGLPSHPGHEVAARQMRGFGGMV 309
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 324 SFE-TGSFEHSKRLVSSKKLSIWAvtVSFGCVNSLLSMPCKMSHASIDPelrKERDFPEDLVRLCCGIENIVDLKKDLLA 402
Cdd:PRK07811 310 SVRlAGGEEAARDFCARTKVFTLA--ESLGGVESLIEHPSAMTHASTAG---SQLEVPDDLVRLSVGIEDVADLLADLEQ 384
|
..
gi 398364309 403 AM 404
Cdd:PRK07811 385 AL 386
|
|
| PRK08247 |
PRK08247 |
methionine biosynthesis PLP-dependent protein; |
4-403 |
1.08e-71 |
|
methionine biosynthesis PLP-dependent protein;
Pssm-ID: 181320 [Multi-domain] Cd Length: 366 Bit Score: 231.13 E-value: 1.08e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 4 KRLDTVVVNTGSQNDQHSASV-PPVYLSTTFKVDLNNEdAQNYDYSRSGNPTRSVLQHQIGKLYRVPQEnvLAVSSGMTA 82
Cdd:PRK08247 3 STIETKLAQIGNRSDERTGTVnPPVYFSTAYRHEGIGE-STGFDYSRTGNPTRGVLEQAIADLEGGDQG--FACSSGMAA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 83 LDVILRglvLLNGTDNhtptIIAGDDLYGGTQRLLNFFKQQSHAVSVHVDTSDFEKFKTVFQSldKVDCVLLESPTNPLC 162
Cdd:PRK08247 80 IQLVMS---LFRSGDE----LIVSSDLYGGTYRLFEEHWKKWNVRFVYVNTASLKAIEQAITP--NTKAIFIETPTNPLM 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 163 KVVDIPRILRFVKciSPDTTVVVDNTMMSGLNCNPLQLnpGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVIN 242
Cdd:PRK08247 151 QETDIAAIAKIAK--KHGLLLIVDNTFYTPVLQRPLEE--GADIVIHSATKYLGGHNDVLAGLVVAKGQELCERLAYYQN 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 243 STGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLEnscgfkptrtnkatktrfvglrSNPDFKlhKSFNNGPGAV 322
Cdd:PRK08247 227 AAGAVLSPFDSWLLIRGMKTLALRMRQHEENAKAIAAFLN----------------------EQPGVT--DVLYPGRGGM 282
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 323 LSFETGSFEHSKRLVSSKKLSIWAVtvSFGCVNSLLSMPCKMSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLA 402
Cdd:PRK08247 283 LSFRLQDEEWVNPFLKSLKLITFAE--SLGGVESFITYPATQTHADIPEEIRIANGVCNRLLRFSVGIENVEDLIADLKQ 360
|
.
gi 398364309 403 A 403
Cdd:PRK08247 361 A 361
|
|
| PRK06176 |
PRK06176 |
cystathionine gamma-synthase; |
5-404 |
7.03e-71 |
|
cystathionine gamma-synthase;
Pssm-ID: 180443 [Multi-domain] Cd Length: 380 Bit Score: 229.40 E-value: 7.03e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 5 RLDTVVVNTGSQNDQHSASVP-PVYLSTTFKVDLNNEdAQNYDYSRSGNPTRSVLQHQIGKLYRVPQEnvLAVSSGMTAL 83
Cdd:PRK06176 2 RMQTKLIHGGISEDTTTGAVSvPIYQTSTYRQDAIGR-PKGYEYSRSGNPTRFALEELIADLEGGVKG--FAFASGLAGI 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 84 DVILRglvlLNGTDNHtptIIAGDDLYGGTQRLLNFFKQQSHAVSVHVDTSDFEKFKTVFQSLDKVdcVLLESPTNPLCK 163
Cdd:PRK06176 79 HAVFS----LFQSGDH---VLLGDDVYGGTFRLFDKVLVKNGLSCTIIDTSDLSQIKKAIKPNTKA--LYLETPSNPLLK 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 164 VVDIPRILRFVKciSPDTTVVVDNTMMSGLNCNPLQLnpGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINS 243
Cdd:PRK06176 150 ITDLAQCASVAK--DHGLLTIVDNTFATPYYQNPLLL--GADIVVHSGTKYLGGHSDVVAGLVTTNNEALAQEIAFFQNA 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 244 TGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENScgfkptrtNKATKTRFVGLRSNPDFKLHKSFNNGPGAVL 323
Cdd:PRK06176 226 IGGVLGPQDSWLLQRGIKTLGLRMEAHQKNALCVAEFLEKH--------PKVEKVYYPGLPTHPNHELAKKQMRGFSGML 297
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 324 SFETGSFEHSKRLVSSKKLSIWAvtVSFGCVNSLLSMPCKMSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAA 403
Cdd:PRK06176 298 SFTLKNDSEAVAFVESLKLFILG--ESLGGVESLVGIPAFMTHACIPKEQREAAGIRDGLVRLSVGIEHEQDLLEDLEQA 375
|
.
gi 398364309 404 M 404
Cdd:PRK06176 376 F 376
|
|
| PRK08045 |
PRK08045 |
cystathionine gamma-synthase; Provisional |
8-400 |
1.31e-68 |
|
cystathionine gamma-synthase; Provisional
Pssm-ID: 169194 [Multi-domain] Cd Length: 386 Bit Score: 223.62 E-value: 1.31e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 8 TVVVNTGSQND-QHSASVPPVYLSTTFK-VDLNNEDAqnYDYSRSGNPTRSVLQHQIGKLyrvpQENVLAV--SSGMTAL 83
Cdd:PRK08045 7 TIAVRSGLNDDeQYGCVVPPIHLSSTYNfTGFNEPRA--HDYSRRGNPTRDVVQRALAEL----EGGAGAVltNTGMSAI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 84 DVILrgLVLLNGTDnhtpTIIAGDDLYGGTQRLLNFFKQQSHAVSVHVDTSDFEKFKTVFQSLDKVdcVLLESPTNPLCK 163
Cdd:PRK08045 81 HLVT--TVFLKPGD----LLVAPHDCYGGSYRLFDSLAKRGCYRVLFVDQGDEQALRAALAEKPKL--VLVESPSNPLLR 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 164 VVDIPRILRFVKCISpdTTVVVDNTMMSGLNCNPLQLnpGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINS 243
Cdd:PRK08045 153 VVDIAKICHLAREAG--AVSVVDNTFLSPALQNPLAL--GADLVLHSCTKYLNGHSDVVAGVVIAKDPDVVTELAWWANN 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 244 TGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKptrtnkatKTRFVGLRSNPDFKLHKSFNNGPGAVL 323
Cdd:PRK08045 229 IGVTGGAFDSYLLLRGLRTLVPRMELAQRNAQAIVKYLQTQPLVK--------KLYHPSLPENQGHEIAARQQKGFGAML 300
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 398364309 324 SFETGSFEHS-KRLVSSkkLSIWAVTVSFGCVNSLLSMPCKMSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDL 400
Cdd:PRK08045 301 SFELDGDEQTlRRFLGG--LSLFTLAESLGGVESLISHAATMTHAGMAPEARAAAGISETLLRISTGIEDGEDLIADL 376
|
|
| PRK08861 |
PRK08861 |
O-succinylhomoserine (thiol)-lyase; |
1-407 |
1.09e-67 |
|
O-succinylhomoserine (thiol)-lyase;
Pssm-ID: 181567 [Multi-domain] Cd Length: 388 Bit Score: 221.31 E-value: 1.09e-67
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 1 MPIKRLDTVVVNTGSQND-QHSASVPPVYLSTTFKVDLNNEDAQnYDYSRSGNPTRSVLQHQIGKLYrvPQENVLAVSSG 79
Cdd:PRK08861 1 MSTRKPATIAVRTGIESDsQYHAVVPPIYLSTNYGFPAFGEVPK-YDYTRSGNPNRGLLEQTLSELE--SGKGAVVTNCG 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 80 MTALDVILRGLVllnGTDNhtpTIIAGDDLYGGTQRLLNFFKQQSHAVSVHVDTSDFEKFKTVFQSLDKVdcVLLESPTN 159
Cdd:PRK08861 78 TSALNLWVSALL---GPDD---LIVAPHDCYGGTYRLFNTRANKGDFKVQFVDQSDAAALDAALAKKPKL--ILLETPSN 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 160 PLCKVVDIPRILRFVKCISpdTTVVVDNTMMSGLNCNPLQLnpGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYF 239
Cdd:PRK08861 150 PLVRVVDIAELCQKAKAVG--ALVAVDNTFLTPVLQKPLEL--GADFVIHSTTKYINGHSDVIGGVLITKTKEHAEELAW 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 240 VINSTGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLEnscgfkptrTNKATKTRF-VGLRSNPDFKLHKSFNNG 318
Cdd:PRK08861 226 WGNCIGATGTPFDSYMTLRGIRTLGARMRVHEESAQQILAYLQ---------TQSLVGTIYhPSLPEHPGHEIAKKQQSG 296
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 319 PGAVLSFE-TGSFEHSKRLVssKKLSIWAVTVSFGCVNSLLSMPCKMSHASIDPELRKERDFPEDLVRLCCGIENIVDLK 397
Cdd:PRK08861 297 FGSMLSFEfAGSFEQLKVFV--KALALFSLAESLGGVESLICHPASMTHRAMGEEALAEAGVSQQLLRLSVGLEDAQDLI 374
|
410
....*....|
gi 398364309 398 KDLLAAMVDA 407
Cdd:PRK08861 375 ADLDQAFAKA 384
|
|
| PRK06234 |
PRK06234 |
methionine gamma-lyase; Provisional |
1-404 |
3.71e-67 |
|
methionine gamma-lyase; Provisional
Pssm-ID: 168478 [Multi-domain] Cd Length: 400 Bit Score: 220.47 E-value: 3.71e-67
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 1 MPIKRLD--TVVVNTGSQND-QHSASVPPVYLSTTFKVDLNNE-------DAQNYDYSRSGNPTRSVLQHQIGKLYRvpQ 70
Cdd:PRK06234 2 ENIKKMGfaTKAIHGGHIGDkQFGSLATPIYQTSTFIFDSAEQggrrfagEESGYIYSRLGNPTSTEVENKLALLEG--G 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 71 ENVLAVSSGMTALDVILrgLVLLNGTDNhtptIIAGDDLYGGTQRLLNffkqqsHAVS------VHVDTSDFEKFKTVFQ 144
Cdd:PRK06234 80 EAAVVAASGMGAISSSL--WSALKAGDH----VVASDTLYGCTFALLN------HGLTrygvevTFVDTSNLEEVRNALK 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 145 SLDKVdcVLLESPTNPLCKVVDIPRILRFVKCISPDTTVVVDNTMMSGLNCNPLQLnpGCDVVYESATKYLNGHHDLMGG 224
Cdd:PRK06234 148 ANTKV--VYLETPANPTLKVTDIKAISNIAHENNKECLVFVDNTFCTPYIQRPLQL--GADVVVHSATKYLNGHGDVIAG 223
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 225 VIISKTPEI-ASKLYFVINSTGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLEnscgfkptRTNKATKTRFVGL 303
Cdd:PRK06234 224 FVVGKEEFInQVKLFGIKDMTGSVIGPFEAFLIIRGMKTLQIRMEKHCKNAMKVAKFLE--------SHPAVEKVYYPGL 295
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 304 RSNPDFKLHKSFNNGPGAVLSFET-GSFEHSKRLVSSKKLSIWAvtVSFGCVNSLLSMPCKMSHASIDPELRKERDFPED 382
Cdd:PRK06234 296 ESFEYYELAKKQMSLPGAMISFELkGGVEEGKVVMNNVKLATLA--VSLGDAETLIQHPASMTHSPYTAEERKEAGISDG 373
|
410 420
....*....|....*....|..
gi 398364309 383 LVRLCCGIENIVDLKKDLLAAM 404
Cdd:PRK06234 374 LVRLSVGLEDVDDIIADLKQAL 395
|
|
| met_gam_lyase |
TIGR01328 |
methionine gamma-lyase; This model describes a methionine gamma-lyase subset of a family of ... |
8-404 |
1.03e-64 |
|
methionine gamma-lyase; This model describes a methionine gamma-lyase subset of a family of PLP-dependent trans-sulfuration enzymes. The member from the parasite Trichomonas vaginalis is described as catalyzing alpha gamma- and alpha-beta eliminations and gamma-replacement reactions on methionine, cysteine, and some derivatives. Likewise, the enzyme from Pseudomonas degrades cysteine as well as methionine. [Energy metabolism, Amino acids and amines]
Pssm-ID: 130395 [Multi-domain] Cd Length: 391 Bit Score: 213.60 E-value: 1.03e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 8 TVVVNTG-SQNDQHSASVPPVYLSTTFKVDlNNEDAQN--------YDYSRSGNPTRSVLQHQIGKLYRVpqENVLAVSS 78
Cdd:TIGR01328 6 TRAIHAGyPPKDQFGALTPPIYQTSTFVFD-SCEQGGNrfagqesgYIYSRLGNPTVSNLEGRIAFLEGT--EAAVATSS 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 79 GMTALDVILrgLVLLNGTDNhtptIIAGDDLYGGTQRLLNFFKQQSHAVSVHVDTSDFEKFKTVFQslDKVDCVLLESPT 158
Cdd:TIGR01328 83 GMGAIAATL--LTILKAGDH----LISDECLYGCTFALLEHALTKFGIQVDFINMAIPEEVKAHIK--DNTKIVYFETPA 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 159 NPLCKVVDIPRILRFVKciSPDTTVVVDNTMMSGLNCNPLQLnpGCDVVYESATKYLNGHHDLMGGVIISKTPEIAS-KL 237
Cdd:TIGR01328 155 NPTMKLIDMERVCRDAH--SQGVKVIVDNTFATPMLTNPVAL--GVDVVVHSATKYIGGHGDVVAGLICGKAELLQQiRM 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 238 YFVINSTGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENscgfKPtrtnKATKTRFVGLRSNPDFKLHKSFNN 317
Cdd:TIGR01328 231 VGIKDMTGSVISPFDAWLILRGLKTLNIRMKRHSENAMKVAEYLKS----HP----AVEKVYYPGFEDHPGHDIAAKQMR 302
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 318 GPGAVLSFE-TGSFEHSKRLVSSKKLSIWAvtVSFGCVNSLLSMPCKMSHASIDPELRKERDFPEDLVRLCCGIENIVDL 396
Cdd:TIGR01328 303 MGGGMITFElKGGFAGAKKLLNNLKLIRLA--VSLGDAETLIQHPASMTHAVVPKEEREAAGITDGMIRLSVGLEDADDL 380
|
....*...
gi 398364309 397 KKDLLAAM 404
Cdd:TIGR01328 381 IADLKQAL 388
|
|
| PRK08776 |
PRK08776 |
O-succinylhomoserine (thiol)-lyase; |
8-408 |
1.97e-62 |
|
O-succinylhomoserine (thiol)-lyase;
Pssm-ID: 181554 [Multi-domain] Cd Length: 405 Bit Score: 208.30 E-value: 1.97e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 8 TVVVNTGSQNDQ-HSASVPPVYLSTTFKVDLNNEDAQnYDYSRSGNPTRSVLQHQIGKLyrvpQENVLAV--SSGMTALD 84
Cdd:PRK08776 15 TAAVRAGIDRDTaYGAVTPPIVLSSNFSFDGFGNKRQ-YDYTRSGNPTRDLLGEALAEL----EGGAGGVitATGMGAIN 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 85 VILRGLvlLNGTDnhtpTIIAGDDLYGGTQRLLNFFKQQSHAVSVHVDTSDFEKFKTVFQSLDKVdcVLLESPTNPLCKV 164
Cdd:PRK08776 90 LVLNAL--LQPGD----TLVVPHDAYGGSWRLFNALAKKGHFALITADLTDPRSLADALAQSPKL--VLIETPSNPLLRI 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 165 VDipriLRFV--KCISPDTTVVVDNTMMSGLNCNPLQLnpGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVIN 242
Cdd:PRK08776 162 TD----LRFVieAAHKVGALTVVDNTFLSPALQKPLEF--GADLVLHSTTKYINGHSDVVGGAVVARDAELHQQLVWWAN 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 243 STGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKptrtnkatKTRFVGLRSNPDFKLHKSFNNGPGAV 322
Cdd:PRK08776 236 ALGLTGSPFDAFLTLRGLRTLDARLRVHQENADAIAALLDGHAAVN--------QVYYPGLASHPGHALAARQQKGFGAM 307
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 323 LSFETGSFEHSKRLVSSkKLSIWAVTVSFGCVNSLLSMPCKMSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLA 402
Cdd:PRK08776 308 LSFELEGGEAAVRAFVD-GLRYFTLAESLGGVESLIAHPASMTHAAMTAEARAAAGISDGLLRLSVGIESAEDLLIDLRA 386
|
....*.
gi 398364309 403 AMVDAD 408
Cdd:PRK08776 387 GLARAE 392
|
|
| PRK08574 |
PRK08574 |
cystathionine gamma-synthase family protein; |
5-400 |
1.19e-60 |
|
cystathionine gamma-synthase family protein;
Pssm-ID: 236298 [Multi-domain] Cd Length: 385 Bit Score: 202.99 E-value: 1.19e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 5 RLDTVVVNTGSQNDQHSASVPPVYLSTTFKVDLN---NEDAQNYDYSRSGNPTRSVLQHQIGKLYRvpQENVLAVSSGMT 81
Cdd:PRK08574 2 RRGTDAVRGYRGSDPYGSLQPPIYLTALFRQEGEaypSDRGFDLKYSREENPTLRPLEEALAKLEG--GVDALAFNSGMA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 82 ALDVILrgLVLLNGTDnhtpTIIAGDDLYGGTQRLL-NFFKQQSHAVSVHVDTSDF-EKFKTVfqsldKVDCVLLESPTN 159
Cdd:PRK08574 80 AISTLF--FSLLKAGD----RVVLPMEAYGTTLRLLkSLEKFGVKVVLAYPSTEDIiEAIKEG-----RTKLVFIETMTN 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 160 PLCKVVDIPRILRfvKCISPDTTVVVDNTMMSGLNCNPLQLnpGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYF 239
Cdd:PRK08574 149 PTLKVIDVPEVAK--AAKELGAILVVDNTFATPLLYRPLRH--GADFVVHSLTKYIAGHNDVVGGVAVAWSGEFLEELWE 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 240 VINSTGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENScgfkptrtNKATKTRFVGLRSNPDFKLHKSFNNGP 319
Cdd:PRK08574 225 WRRRLGTIMQPFEAYLVLRGLKTLEVRFERQCRNAMAIAEFLSEH--------PKVAEVYYPGLPSDPYHGVAKRLFGKD 296
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 320 --GAVLSFE-TGSFEHSKRLVssKKLSIWAVTVSFGCVNSLLSMPCKMSHASIDPELRKERDFPEDLVRLCCGIENIVDL 396
Cdd:PRK08574 297 lyGGVVSFRvKGGRDAVLKFL--RSLKLIKPSPSLGGVESLATYPVKSAASPIPEEDRKALGITEDLVRLSVGLEDVEDL 374
|
....
gi 398364309 397 KKDL 400
Cdd:PRK08574 375 IEDL 378
|
|
| PRK08249 |
PRK08249 |
cystathionine gamma-synthase family protein; |
8-404 |
1.53e-60 |
|
cystathionine gamma-synthase family protein;
Pssm-ID: 236202 [Multi-domain] Cd Length: 398 Bit Score: 203.05 E-value: 1.53e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 8 TVVVNTGSQNDQ-HSASVPPVYLSTTFKVDLNNE-------DAQNYDYSRSGNPTRSVLQHQIGKLYRVpqENVLAVSSG 79
Cdd:PRK08249 11 TKAVWAGEKEYLpYGATQVPVVLSVAYGYDDIDEwydvalgKKPGHIYSRNTNPTVQAFEEKVRILEGA--EAATAFSTG 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 80 MTALDVILRGLvLLNGTdnhtpTIIAGDDLYGGTQRL-LNFFKQQSHAVSVhVDTSDFEKFKTVFQSldKVDCVLLESPT 158
Cdd:PRK08249 89 MAAISNTLYTF-LKPGD-----RVVSIKDTYGGTNKIfTEFLPRMGVDVTL-CETGDHEQIEAEIAK--GCDLLYLETPT 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 159 NPLCKVVDIPRILRFVKciSPDTTVVVDNTMMSGLNCNPLQLnpGCDVVYESATKYLNGHHDLMGGVIISkTPEIASKLY 238
Cdd:PRK08249 160 NPTLKIVDIERLAAAAK--KVGALVVVDNTFATPINQNPLAL--GADLVIHSATKFLSGHADALGGVVCG-SKELMEQVY 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 239 FVINSTGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENScgfkptrtNKATKTRFVGLRSNPDFKLHKSFNNG 318
Cdd:PRK08249 235 HYREINGATMDPMSAYLILRGMKTLKLRVRQQQESAMALAKYLQTH--------PKVEAVYYPGLETHPNHEIAKAQMRG 306
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 319 PGAVLSFE-TGSFEHSKRLVSskKLSIWAVTVSFGCVNSLLSMPCKMSHASIDPELRKERDFPEDLVRLCCGIENIVDLK 397
Cdd:PRK08249 307 FGGILSFVlKGGMDTVKRLLP--KLRYAHRAANLGAVETIYGPARTTSHVENTLEERAALGIPEGLVRISVGIEDTEDLI 384
|
....*..
gi 398364309 398 KDLLAAM 404
Cdd:PRK08249 385 ADLEQAF 391
|
|
| MET17 |
COG2873 |
O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent [Amino acid ... |
5-403 |
7.20e-60 |
|
O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent [Amino acid transport and metabolism]; O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent is part of the Pathway/BioSystem: Methionine biosynthesis
Pssm-ID: 442120 [Multi-domain] Cd Length: 428 Bit Score: 201.80 E-value: 7.20e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 5 RLDTVVVNTGSQNDQHS-ASVPPVYLSTTFKVDlNNEDAQN--------YDYSRSGNPTRSVLQHQIGKLyrvpqEN--- 72
Cdd:COG2873 7 GFETLALHAGQEPDPTTgARAVPIYQTTSYVFD-DAEHAADlfalkepgNIYTRIMNPTTDVLEKRIAAL-----EGgva 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 73 VLAVSSGMTALDVILrgLVLLNGTDNhtptIIAGDDLYGGTQRLL-NFFKQQshAVSVH-VDTSDFEKFKTVFQslDKVD 150
Cdd:COG2873 81 ALATASGQAAITLAI--LNLAEAGDH----IVASSSLYGGTYNLFaHTLPRL--GIEVRfVDPDDPEAFEAAID--PNTK 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 151 CVLLESPTNPLCKVVDIPRILRfvkcIS-----PdttVVVDNTMMSGLNCNPLQLnpGCDVVYESATKYLNGHHDLMGGV 225
Cdd:COG2873 151 AIFGETIGNPALDVLDIEAIAE----IAhehgvP---LIVDNTFATPYLCRPIEH--GADIVVHSATKYIGGHGTSIGGV 221
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 226 II----------SKTPEIAS---------------KLYFVI-------NSTGAGLSPMDSWLLVRGLKTLGVRLYQQQRN 273
Cdd:COG2873 222 IVdggnfdwaanGKFPELTEpdpsyhglvyteafgNAAFITkarvqllRDLGAALSPFNAFLLLQGLETLSLRMERHVEN 301
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 274 AMILAHWLENScgfkPtrtnKATKTRFVGLRSNPDFKL-HKSFNNGPGAVLSFE-TGSFEHSKRLVSSkkLSIWAVTVSF 351
Cdd:COG2873 302 ALKVAEFLEAH----P----KVAWVNYPGLPSHPYHELaQKYLPKGAGGVLTFGlKGGREAGKKFIDS--LKLFSHLANI 371
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|..
gi 398364309 352 GCVNSLLSMPCKMSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAA 403
Cdd:COG2873 372 GDAKSLVIHPASTTHSQLSEEEQAAAGVTPDLIRLSVGIEDIDDIIADLDQA 423
|
|
| PRK07269 |
PRK07269 |
cystathionine gamma-synthase; Reviewed |
4-404 |
8.04e-60 |
|
cystathionine gamma-synthase; Reviewed
Pssm-ID: 235983 Cd Length: 364 Bit Score: 200.05 E-value: 8.04e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 4 KRLDTVVVNTGSQNDQHS-ASVPPVYLSTTFKvdlNNEDAQN--YDYSRSGNPTRSVLQHQIGKLYRVpqENVLAVSSGM 80
Cdd:PRK07269 5 LHINTILAQAGIKSDEATgALVTPLHFSTTYQ---HPEFGQStgFDYTRTKNPTRAKLEETLAAIESA--DYALATSSGM 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 81 TALdvilrglVLLNGTDNHTPTIIAGDDLYGGTQRllnFFKQQSHAVSVHVDTSDFEKfKTVFQSLDKVDCVLLESPTNP 160
Cdd:PRK07269 80 SAI-------VLAFSVFPVGSKVVAVRDLYGGSFR---WFNQQEKEGRFHFTYANTEE-ELIAAIEEDTDIVYIETPTNP 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 161 LCKVVDIPRILRfvKCISPDTTVVVDNTMMSGLNCNPLQLnpGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFV 240
Cdd:PRK07269 149 LMVEFDIEKVAK--LAHAKGAKVIVDNTFYSPIYQRPIEL--GADIVLHSATKYLSGHNDVLAGVVVTNDLELYEKLFYN 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 241 INSTGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKptrtnkatktrfvglrsnpdfklhKSFNNGPG 320
Cdd:PRK07269 225 LNTTGAVLSPFDSYLLMRGLKTLSLRMERSTANAQEVVAFLKKSPAVK------------------------EVLYTGKG 280
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 321 AVLSFETGSFEHSKRLVSSkkLSIWAVTVSFGCVNSLLSMPCKMSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDL 400
Cdd:PRK07269 281 GMISFKVADETRIPHILNS--LKVFTFAESLGGVESLITYPTTQTHADIPAEVRHSYGLTDDLLRLSIGIEDARDLIADL 358
|
....
gi 398364309 401 LAAM 404
Cdd:PRK07269 359 KQAL 362
|
|
| PRK06767 |
PRK06767 |
methionine gamma-lyase; Provisional |
1-404 |
2.43e-58 |
|
methionine gamma-lyase; Provisional
Pssm-ID: 180685 [Multi-domain] Cd Length: 386 Bit Score: 196.99 E-value: 2.43e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 1 MPIKRLDTVVVNTGSQNDQHSASV-PPVYLSTTFKVD--------LNNEDAqNYDYSRSGNPTRSVLQHQIGKLYRvpQE 71
Cdd:PRK06767 1 MKKKHMETALIHHGYTSEEHKGSLtPPLFQTSTFTFEtaqqgeasFAGVDP-SYIYSRLGNPTVKLFEERMAVLEG--GE 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 72 NVLAVSSGMTALDVILRGLVLLNgtdNHtptIIAGDDLYGGTQRLLNFFKQQshaVSVHVDTSDFEKFKTVF-QSLDKVD 150
Cdd:PRK06767 78 EALAFGSGMAAISATLIGFLKAG---DH---IICSNGLYGCTYGFLEVLEEK---FMITHSFCDMETEADIEnKIRPNTK 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 151 CVLLESPTNPLCKVVDIPRILRFVKciSPDTTVVVDNTMMSGLNCNPLQLnpGCDVVYESATKYLNGHHDLMGGVIISKT 230
Cdd:PRK06767 149 LIFVETPINPTMKLIDLKQVIRVAK--RNGLLVIVDNTFCSPYLQRPLEL--GCDAVVHSATKYIGGHGDVVAGVTICKT 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 231 PEIASKLYFVINSTGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENscgfkptrtNKATKTRFVglrsnPDFK 310
Cdd:PRK06767 225 RALAEKIRPMRKDIGGIMAPFDAWLLLRGLKTLAVRMDRHCDNAEKIVSFLKN---------HDAVEGVWY-----PEGE 290
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 311 LHKSFNNGPGAVLSFE-TGSFEHSKRLVSskKLSIWAVTVSFGCVNSLLSMPCKMSHASIDPELRKERDFPEDLVRLCCG 389
Cdd:PRK06767 291 LASRQMKRGGGVISFSiKGGKEETQAFIN--DLHFITIAVSLGDTETLIQHPATMTHAAIPAELRQEMGIYDNLIRLSVG 368
|
410
....*....|....*
gi 398364309 390 IENIVDLKKDLLAAM 404
Cdd:PRK06767 369 LESWEDIVSDLEQAL 383
|
|
| PRK06434 |
PRK06434 |
cystathionine gamma-lyase; Validated |
4-404 |
9.03e-57 |
|
cystathionine gamma-lyase; Validated
Pssm-ID: 102374 [Multi-domain] Cd Length: 384 Bit Score: 192.81 E-value: 9.03e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 4 KRLDTVVVNTGSQNDQHSASV-PPVYLSTTF-------KVDLNNEDAQNYDYSRSGNPTRSVLQHQigklYRVPQ--ENV 73
Cdd:PRK06434 7 NGFNTRAVQSGELRDPRFGNVtTPIFETSTFvypnsekEAYMDSTRGMPYIYTRWGNPTVQAFEEK----YAVLEnaEHA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 74 LAVSSGMTALDVILRGLVllngtdNHTPTIIAGDDLYGGTqrlLNFFKQQSHAVSVHVDTSDFEKFKTVFQSLDKVDCVL 153
Cdd:PRK06434 83 LSFSSGMGAITSAILSLI------KKGKRILSISDLYGQT---FYFFNKVLKTLGIHVDYIDTDRLNSLDFDPSNYDLIY 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 154 LESPTNPLCKVVDIPRILRFVKcispDTTVVVDNTMMSGLNCNPLQLnpGCDVVYESATKYLNGHHDLMGGVIISKTPEI 233
Cdd:PRK06434 154 AESITNPTLKVPDIKNVSSFCH----ENDVIVDATFASPYNQNPLDL--GADVVIHSATKYISGHSDVVMGVAGTNNKSI 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 234 ASKLYFVINSTGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLenscgfkptRTNKATktrfvgLRSN-PDFKLH 312
Cdd:PRK06434 228 FNNLVERRKTLGSNPDPIQAYLALRGLKTLGLRMEKHNKNGMELARFL---------RDSKKI------SNVYyPDTEIG 292
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 313 KSFNNGPGAVLSFETGSFEHSKRLVssKKLSIWAVTVSFGCVNSLLSMPCKMSHASIDPELRKERDFPEDLVRLCCGIEN 392
Cdd:PRK06434 293 KKVLRGFGGMLSFELRSMEDVHKFI--RNLEIPMVAASLGGVESLITLPVETSHSSLSPEERERLGISDNLVRFSIGIED 370
|
410
....*....|..
gi 398364309 393 IVDLKKDLLAAM 404
Cdd:PRK06434 371 IDDLIKDIENAL 382
|
|
| PRK07503 |
PRK07503 |
methionine gamma-lyase; Provisional |
18-404 |
1.26e-56 |
|
methionine gamma-lyase; Provisional
Pssm-ID: 181005 [Multi-domain] Cd Length: 403 Bit Score: 192.71 E-value: 1.26e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 18 DQHSASVPPVYLSTTFKVDlNNE--------DAQNYDYSRSGNPTRSVLQHQIGKLYRvpQENVLAVSSGMTALDVILrg 89
Cdd:PRK07503 23 DHGGALVPPVYLTATFAFP-TAEygaecfagEEEGHFYSRISNPTLALLEQRMASLEG--GEAAVALASGMGAITATL-- 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 90 LVLLNGTDNhtptIIAGDDLYGGTQRLLNFFKQQSHAVSVHVDTSDFEKFKTVFQslDKVDCVLLESPTNPLCKVVDIPR 169
Cdd:PRK07503 98 WTLLRPGDE----VIVDQTLYGCTFAFLHHGLGEFGVTVRHVDLTDPAALKAAIS--DKTRMVYFETPANPNMRLVDIAA 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 170 ILRFVKciSPDTTVVVDNTMMSGLNCNPLQLnpGCDVVYESATKYLNGHHDLMGGVIISKTPEIAS-KLYFVINSTGAGL 248
Cdd:PRK07503 172 VAEIAH--GAGAKVVVDNTYCTPYLQRPLEL--GADLVVHSATKYLGGHGDITAGLVVGGKALADRiRLEGLKDMTGAVM 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 249 SPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLEnscgfkptRTNKATKTRFVGLRSNPDFKLHKSFNNGPGAVLSFE-T 327
Cdd:PRK07503 248 SPFDAFLLMRGLKTLALRMDRHCASAQAVAEWLA--------RHPAVELVHYPGLPSFAQHALAQRQMALPGGMIAFElK 319
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 398364309 328 GSFEHSKRLVSskKLSIWAVTVSFGCVNSLLSMPCKMSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAM 404
Cdd:PRK07503 320 GGIAAGRRFMN--ALQLFARAVSLGDAESLAQHPASMTHSTYTPEERAEHGISEGLVRLSVGLEDVADILADLAQAL 394
|
|
| OAH_OAS_sulfhy |
TIGR01326 |
OAH/OAS sulfhydrylase; This model describes a distinct clade of the Cys/Met metabolism ... |
5-400 |
3.44e-55 |
|
OAH/OAS sulfhydrylase; This model describes a distinct clade of the Cys/Met metabolism pyridoxal phosphate-dependent enzyme superfamily. Members include examples of OAH/OAS sulfhydrylase, an enzyme with activity both as O-acetylhomoserine (OAH) sulfhydrylase (EC 2.5.1.49) and O-acetylserine (OAS) sulphydrylase (EC 2.5.1.47). An alternate name for OAH sulfhydrylase is homocysteine synthase. This model is designated subfamily because it may or may not have both activities. [Amino acid biosynthesis, Aspartate family, Amino acid biosynthesis, Serine family]
Pssm-ID: 273555 [Multi-domain] Cd Length: 418 Bit Score: 189.49 E-value: 3.44e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 5 RLDTVVVNTGSQND-QHSASVPPVYLSTTFKVDLNNEDAQNYD-------YSRSGNPTRSVLQHQIGKLyrvpqEN---V 73
Cdd:TIGR01326 1 HFETLQLHAGQEPDpTTGSRAVPIYQTTSYVFDSTEHAAALFGlqepgniYSRLMNPTTDVLEQRIAAL-----EGgvaA 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 74 LAVSSGMTALDVILrgLVLLNGTDNhtptIIAGDDLYGGTQRLLNF-FKQQSHAVSVhVDTSDFEKFKTVFQslDKVDCV 152
Cdd:TIGR01326 76 LAVASGQAAITYAI--LNLAGAGDN----IVSSSYLYGGTYNLFSHtLKRLGIEVRF-VDPDDPESLEKAID--ENTKAV 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 153 LLESPTNPLCKVVDIPRILRFVKciSPDTTVVVDNTMMSGLNCNPLQLnpGCDVVYESATKYLNGHHDLMGGVIISK--- 229
Cdd:TIGR01326 147 FAETIGNPQINVLDIEAIAEVAH--RHGIPLIVDNTFATPYLCRPIKH--GADIVVHSATKYIGGHGTAIGGVIVDGgkf 222
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 230 -----------TP----------EIASKLYFVINS-------TGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWL 281
Cdd:TIGR01326 223 dwnngrfplftTPdpsyhglvftETLGNPAFILKArvqllrdLGAALSPFNAFLLLQGLETLSLRMERHVENALKVAEFL 302
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 282 ENScgfkptrtNKATKTRFVGLRSNPDFKL-HKSFNNGPGAVLSFET-GSFEHSKRLVSSKKLSIWAVTVsfGCVNSLLS 359
Cdd:TIGR01326 303 ESH--------PDVAWVNYPGLASHPHHALaKKYLPKGFGAVLSFEIkGGREAGKKFIDALKLASHLANV--GDAKSLVI 372
|
410 420 430 440
....*....|....*....|....*....|....*....|.
gi 398364309 360 MPCKMSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDL 400
Cdd:TIGR01326 373 HPASTTHSQLSEEEQLKAGVTPGLIRLSVGIENIDDIIADL 413
|
|
| PRK07582 |
PRK07582 |
cystathionine gamma-lyase; Validated |
9-404 |
1.91e-54 |
|
cystathionine gamma-lyase; Validated
Pssm-ID: 236061 Cd Length: 366 Bit Score: 185.97 E-value: 1.91e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 9 VVVNTGSQNDQHSASVPPVYLSTTFKVDlNNEDAQNYDYSRSGNPTRSVLQHQIGKLYRVPqenVLAVSSGMTALDVILR 88
Cdd:PRK07582 8 SVHAGGPEAVPGEPVLPGPVFAAPYHLS-PGEPTGPDTYGRASNPTWRALEAALGELEGAE---ALVFPSGMAAITAVLR 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 89 glVLLNGTDnhtpTIIAGDDLYGGTQRLLN-FFKQQShaVSVH-VDTSDFekfktVFQSLDKVDCVLLESPTNPLCKVVD 166
Cdd:PRK07582 84 --ALLRPGD----TVVVPADGYYQVRALAReYLAPLG--VTVReAPTAGM-----AEAALAGADLVLAETPSNPGLDVCD 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 167 IPRILRfvKCISPDTTVVVDNTMMSGLNCNPLQLnpGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINSTGA 246
Cdd:PRK07582 151 LAALAA--AAHAAGALLVVDNTTATPLGQRPLEL--GADLVVASDTKALTGHSDLLLGYVAGRDPELMAAVERWRLLAGA 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 247 GLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLenscgfkptRTNKA-TKTRFVGLRSNPDFKLHKSFNNGPGAVLSF 325
Cdd:PRK07582 227 IPGPFEAWLAHRSLGTLGLRFARQCANALAVAELL---------AGHPAvRGVRYPGLPGDPAHEVAARQMRRFGGLVSF 297
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 398364309 326 ETGSFEHSKRLVSSKKLsiWAVTVSFGCVnsllsmpckmsHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAM 404
Cdd:PRK07582 298 ELADAAAAERFVAASRL--VVAATSFGGV-----------HTSADRRARWGDAVPEGFVRLSCGIEDTDDLVADLERAL 363
|
|
| O_suc_HS_sulf |
TIGR01325 |
O-succinylhomoserine sulfhydrylase; This model describes O-succinylhomoserine sulfhydrylase, ... |
7-404 |
6.76e-53 |
|
O-succinylhomoserine sulfhydrylase; This model describes O-succinylhomoserine sulfhydrylase, one of several related pyridoxal phosphate-dependent enzymes of cysteine and methionine metabolism. This enzyme is part of an alternative pathway of homocysteine biosynthesis, a step in methionine biosynthesis. [Amino acid biosynthesis, Aspartate family]
Pssm-ID: 188131 Cd Length: 381 Bit Score: 182.35 E-value: 6.76e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 7 DTVVVNTGSQNDQHSASVPPVYLSTTFKVDlNNEDAQN--------YDYSRSGNPTRSVLQHQIGKLYRVPQenVLAVSS 78
Cdd:TIGR01325 1 ATLAVRGGMLRSGFEETAEALYLTSGYVYD-SAAVAAKrfagelpgFVYSRYGNPTVSVFEERLALLEGAEA--AVATAS 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 79 GMTALDVILRGLVllnGTDNHtptIIAGDDLYGGTQRLLNFFKQQSHAVSVHVDTSDFEKFKTVFQSLDKVdcVLLESPT 158
Cdd:TIGR01325 78 GMAAIFAALMALL---GAGDH---VVASRSLFGSCFVVCSEILPRFGVQTVFVDGTDLSAWEAALKPNTKA--VFVETPS 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 159 NPLCKVVDIPRILRFVKCISpdTTVVVDNTMMSGLNCNPLQLnpGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLY 238
Cdd:TIGR01325 150 NPLQELVDIAAVAELAHAAG--AKVVVDNVFATPLLQQPLKL--GADVVVYSATKHIDGQGRVLGGAILGSEEYMDEPVQ 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 239 FVINSTGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLEnscgfkptRTNKATKTRFVGLRSNPDFKLHKSFNNG 318
Cdd:TIGR01325 226 KLLRHTGPAMSPFNAWVLLKGLETLAIRVQHQNASALAIAEWLN--------GHPSVQWVYYPGLPSHPQHELAKRQMSG 297
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 319 PGAVLSFETGSFEHSKRLVSskKLSIWAVTVSFGCVNSLLSMPCKMSHASIDPELRKERDFPEDLVRLCCGIENIVDLKK 398
Cdd:TIGR01325 298 GGTVVTFDLDCRQAAFKVLD--AMRLVDISNNLGDAKSTITHPATTTHRRMGPEERAAAGIGDGLVRLSVGLEDVDDLIA 375
|
....*.
gi 398364309 399 DLLAAM 404
Cdd:TIGR01325 376 DIDRAL 381
|
|
| PRK06460 |
PRK06460 |
hypothetical protein; Provisional |
17-404 |
9.48e-52 |
|
hypothetical protein; Provisional
Pssm-ID: 235807 [Multi-domain] Cd Length: 376 Bit Score: 179.26 E-value: 9.48e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 17 NDQHSASVPPVYLSTTFKVdlnnEDAQNYDYSRSGNPTRSVLQHQIGKLYRVpqENVLAVSSGMTALDVILrgLVLLNGT 96
Cdd:PRK06460 13 DEATGAITTPIYQTTAYHY----PEGEKYRYSREANPTVLELTKKIVELENA--EMGVAFSSGMGAISTTA--LALLKPG 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 97 DnhtpTIIAGDDLYGgtqRLLNFFKQQSHAVSVHVDTSD------FEKFKTvfqslDKVDCVLLESPTNPLCKVVDIPRI 170
Cdd:PRK06460 85 N----SVLVHRDMFG---RSYRFFTDYLKNWGVNVDASNpgsdniIEKAKS-----KRYDVVFVENITNPLLRVVDITEL 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 171 LRFvkCISPDTTVVVDNTMMSGLNCNPLQLnpGCDVVYESATKYLNGHHDLMGGVIISKTpEIASKLYFVINSTGAGLSP 250
Cdd:PRK06460 153 SKV--CKENGSILIVDATFSTPINQKPLEL--GADIVVHSASKFLAGHNDVIAGLAAGYG-KLLNVIDQMRRTLGTSLDP 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 251 MDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENScgfkptrtNKATKTRFVGLRSNPDFKLHKSFNNGPGAVLSFET-GS 329
Cdd:PRK06460 228 HAAYLTLRGIKTLKIRMDVINRNAEQIAEFLEGH--------PKVVKVYYPGLKSHVDYEIARRVLKGFGGVLSFEVnGG 299
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 398364309 330 FEHSKRLVSSKKLSIWAVTVsfGCVNSLLSMPCKMSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAM 404
Cdd:PRK06460 300 QESALKVMKSLKLIIPAQTL--GGVNSVISHPATMSHRTLSLEERKIVGITDSLLRLSVGIEDVNDLIEDLDRAL 372
|
|
| PRK08133 |
PRK08133 |
O-succinylhomoserine sulfhydrylase; Validated |
6-401 |
3.48e-51 |
|
O-succinylhomoserine sulfhydrylase; Validated
Pssm-ID: 181244 [Multi-domain] Cd Length: 390 Bit Score: 177.89 E-value: 3.48e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 6 LDTVVVNTGSQNDQHSASVPPVYLSTTFKVDlNNEDA--------QNYDYSRSGNPTRSVLQHQIGKLYRVpqENVLAVS 77
Cdd:PRK08133 7 FDTLAVRAGQLRSPFGEHSEALFLTSSFVFE-SAAEAaarfageePGNIYSRFTNPTVTMFQERLAALEGA--EACVATA 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 78 SGMTALDVILRGLvlLNGTDNhtptIIAGDDLYGGTQRLL-NFFKQQSHAVSvHVDTSDFEKFKTVFQSLDKVdcVLLES 156
Cdd:PRK08133 84 SGMAAILAVVMAL--LQAGDH----VVSSRSLFGSTVSLFeKIFARFGIETT-FVDLTDLDAWRAAVRPNTKL--FFLET 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 157 PTNPLCKVVDIPRILRFVKciSPDTTVVVDNTMmsglnCNP-LQ--LNPGCDVVYESATKYLNGHHDLMGGVIISKTpEI 233
Cdd:PRK08133 155 PSNPLTELADIAALAEIAH--AAGALLVVDNCF-----CTPaLQqpLKLGADVVIHSATKYLDGQGRVLGGAVVGSK-EL 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 234 ASKLYFVINSTGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENscgfKPtrtnKATKTRFVGLRSNPDFKLHK 313
Cdd:PRK08133 227 MEEVFGFLRTAGPTLSPFNAWVFLKGLETLSLRMEAHSANALALAEWLEA----HP----GVERVFYPGLPSHPQHELAK 298
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 314 SFNNGPGAVLSFET-GSFEHSKRLVSSKKL-SIwavTVSFGCVNSLLSMPCKMSHASIDPELRKERDFPEDLVRLCCGIE 391
Cdd:PRK08133 299 RQQKGGGAIVSFEVkGGREAAWRVIDATRLiSI---TANLGDTKTTITHPATTTHGRLSPEARAAAGITEGLIRVAVGLE 375
|
410
....*....|
gi 398364309 392 NIVDLKKDLL 401
Cdd:PRK08133 376 DVADIKADLA 385
|
|
| PRK05994 |
PRK05994 |
O-acetylhomoserine aminocarboxypropyltransferase; Validated |
6-404 |
1.72e-39 |
|
O-acetylhomoserine aminocarboxypropyltransferase; Validated
Pssm-ID: 180344 [Multi-domain] Cd Length: 427 Bit Score: 147.55 E-value: 1.72e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 6 LDTVVVNTGSQNDQHS-ASVPPVYLSTTFKVDLNNEDAQNYD-------YSRSGNPTRSVLQHQIGKLyrvpqEN---VL 74
Cdd:PRK05994 8 FATLAVHAGAQPDPTTgARATPIYQTTSFVFNDADHAASLFGlqafgniYTRITNPTNAVLEERVAAL-----EGgtaAL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 75 AVSSGMTALDVILRglVLLNGTDNhtptIIAGDDLYGGTqrlLNFFkqqSHAVS------VHVDTSDFEKFKTvfQSLDK 148
Cdd:PRK05994 83 AVASGHAAQFLVFH--TLLQPGDE----FIAARKLYGGS---INQF---GHAFKsfgwqvRWADADDPASFER--AITPR 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 149 VDCVLLESPTNPLCKVVDIPRILRFVKciSPDTTVVVDNTMMSGLNCNPLQlnPGCDVVYESATKYLNGHHDLMGGVII- 227
Cdd:PRK05994 149 TKAIFIESIANPGGTVTDIAAIAEVAH--RAGLPLIVDNTLASPYLIRPIE--HGADIVVHSLTKFLGGHGNSMGGIIVd 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 228 ---------SKTP---------------EIASKLYFVI-------NSTGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMI 276
Cdd:PRK05994 225 ggtfdwsksGKYPmlseprpeyhglvlhETFGNFAFAIaarvlglRDLGPAISPFNAFLILTGIETLPLRMQRHSDNALA 304
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 277 LAHWLENScgfkptrtNKATKTRFVGLRSNPDFKLHKSFN-NGPGAVLSFE-TGSFEHSKRLVSSKKLsiWAVTVSFGCV 354
Cdd:PRK05994 305 VAEWLKGH--------PKVSWVNYAGLPDDPYHALAQKYSpKGAGAVFTFGlKGGYEAGVKLVSSLKL--FSHLANIGDT 374
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|
gi 398364309 355 NSLLSMPCKMSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAM 404
Cdd:PRK05994 375 RSLVIHPASTTHRQLTDEQKVAAGAGPDVVRLSIGIEDVDDIIADLEQAL 424
|
|
| PRK07504 |
PRK07504 |
O-succinylhomoserine sulfhydrylase; Reviewed |
5-404 |
1.52e-38 |
|
O-succinylhomoserine sulfhydrylase; Reviewed
Pssm-ID: 168979 [Multi-domain] Cd Length: 398 Bit Score: 144.13 E-value: 1.52e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 5 RLDTVVVNTGSQNDQHSASVPPVYLSTTFKVDLNNE-------DAQNYDYSRSGNPTRSVLQHQIGKLYRVpqENVLAVS 77
Cdd:PRK07504 10 RPATRLVHSGTLRSQFGETSEALFLTQGFVYDTAEAaearfkgEDPGFIYSRYSNPTVDMFEKRMCALEGA--EDARATA 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 78 SGMTALDVILrgLVLLNGTDNhtptIIAGDDLYGGTQRLLNFFKQQSHAVSVHVDTSDFEKFKTVFQSLDKVdcVLLESP 157
Cdd:PRK07504 88 SGMAAVTAAI--LCQVKAGDH----VVAARALFGSCRYVVETLLPRYGIESTLVDGLDLDNWEKAVRPNTKV--FFLESP 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 158 TNPLCKVVDIPRILRFVKCISpdTTVVVDNTMMSGLNCNPLQLnpGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKL 237
Cdd:PRK07504 160 TNPTLEVIDIAAVAKIANQAG--AKLVVDNVFATPLFQKPLEL--GAHIVVYSATKHIDGQGRCLGGVVLSDKAWIEEHL 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 238 YFVINSTGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENScgfkptrtNKATKTRFVGLRSNPDFKLHKSFNN 317
Cdd:PRK07504 236 QDYFRHTGPSLSPFNAWTLLKGLETLPVRVRQQTESAAAIADFLAGH--------PKVARVIYPGRADHPQADIIAKQMT 307
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 318 GPGAVLSFET-GSFEHSKRLVSSkkLSIWAVTVSFGCVNSLLSMPCKMSHASIDPELRKERDFPEDLVRLCCGIENIVDL 396
Cdd:PRK07504 308 GGSTLVAFELkGGKEAAFRFLNA--LKIVRISNNLGDAKSLITHPATTTHKNLSPEARAELGISEGFLRLSAGLEDTDDL 385
|
....*...
gi 398364309 397 KKDLLAAM 404
Cdd:PRK07504 386 IEDLAAAL 393
|
|
| PRK07810 |
PRK07810 |
O-succinylhomoserine sulfhydrylase; Provisional |
5-404 |
5.23e-38 |
|
O-succinylhomoserine sulfhydrylase; Provisional
Pssm-ID: 236103 [Multi-domain] Cd Length: 403 Bit Score: 142.95 E-value: 5.23e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 5 RLDTVVVNTGSQNDQHSASVPPVYLSTTFKVDlNNEDAQ--------NYDYSRSGNPTRSVLQHQIGKLYRVpqENVLAV 76
Cdd:PRK07810 15 SQATIGVRGGLLRSGFEETAEALYLTSGYVYE-SAAAAEaaftgeldRFVYSRYGNPTVSMFEERLRLIEGA--EACFAT 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 77 SSGMTALDVILrGLVLLNGTdnhtpTIIAGDDLYGGTQRLLNFFKQQSHAVSVHVDTSDFEKFKTVFQSldKVDCVLLES 156
Cdd:PRK07810 92 ASGMSAVFTAL-GALLGAGD-----RLVAARSLFGSCFVVCNEILPRWGVETVFVDGEDLSQWEEALSV--PTQAVFFET 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 157 PTNPLCKVVDIPRILRFVKciSPDTTVVVDNTMMSGLNCNPLQLnpGCDVVYESATKYLNGHHDLMGGVIISKTPEIASK 236
Cdd:PRK07810 164 PSNPMQSLVDIAAVSELAH--AAGAKVVLDNVFATPLLQRGLPL--GADVVVYSGTKHIDGQGRVLGGAILGDREYIDGP 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 237 LYFVINSTGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGfkptrtnkATKTRFVGLRSNPDFKLHKSFN 316
Cdd:PRK07810 240 VQKLMRHTGPALSAFNAWVLLKGLETLALRVRHSNASALRIAEFLEGHPA--------VRWVRYPFLPSHPQYDLAKRQM 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 317 NGPGAVLSFE-TGSFEHSKRLVSS--KKLSIWAVTVSFGCVNSLLSMPCKMSHASIDPELRKERDFPEDLVRLCCGIENI 393
Cdd:PRK07810 312 SGGGTVVTFElDAPEDAAKKRAFEvlDKLRVIDISNNLGDAKSLITHPATTTHRAMGPEGRAAIGLGDGVVRLSVGLEDT 391
|
410
....*....|.
gi 398364309 394 VDLKKDLLAAM 404
Cdd:PRK07810 392 DDLIADLDRAL 402
|
|
| PRK06084 |
PRK06084 |
bifunctional O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase; |
5-404 |
7.73e-37 |
|
bifunctional O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase;
Pssm-ID: 180392 [Multi-domain] Cd Length: 425 Bit Score: 140.04 E-value: 7.73e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 5 RLDTVVVNTGSQNDQHSASVP-PVYLSTTFKVDLNNEDAQNYD-------YSRSGNPTRSVLQHQIGKLyrvpqEN---V 73
Cdd:PRK06084 2 KLETLAIHAGYSPDPTTKAVAvPIYQTTSYAFDDTQHGADLFDlkvpgniYTRIMNPTNDVLEQRVAAL-----EGgvgA 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 74 LAVSSGMTALDVILRGLVllNGTDNhtptIIAGDDLYGGTQRLL--NFFKQQSHA-VSVHVDTSDFEKFKTvfqslDKVD 150
Cdd:PRK06084 77 LAVASGMAAITYAIQTIA--EAGDN----IVSVAKLYGGTYNLLahTLPRIGIETrFAAHDDIAALEALID-----ERTK 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 151 CVLLESPTNPLCKVVDIPRILRFVKciSPDTTVVVDNTMMSGLNCNPLQlnPGCDVVYESATKYLNGHHDLMGGVIIS-- 228
Cdd:PRK06084 146 AVFCESIGNPAGNIIDIQALADAAH--RHGVPLIVDNTVATPVLCRPFE--HGADIVVHSLTKYIGGHGTSIGGIVVDsg 221
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 229 KTPEIASKLYFVI-------------------------------NSTGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMIL 277
Cdd:PRK06084 222 KFPWAEHKERFALlntpdpsyhgvtyteafgpaafigrcrvvplRNMGAALSPFNAFLILQGLETLALRMERHTENALKV 301
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 278 AHWLENScgfkptrtNKATKTRFVGLRSNPDFKLHKSFNNG-PGAVLSFE-TGSFEHSKRLVSSKKLSIWAVTVsfGCVN 355
Cdd:PRK06084 302 ARYLQQH--------PQVAWVKYAGLPDHPEHELARRYMGGkPASILSFGiKGGQAAGARFIDALKLVVRLVNI--GDAK 371
|
410 420 430 440
....*....|....*....|....*....|....*....|....*....
gi 398364309 356 SLLSMPCKMSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAM 404
Cdd:PRK06084 372 SLACHPASTTHRQLNDEELEKAGVSRDMVRLSIGIEHIDDIIADLAQAL 420
|
|
| PRK08248 |
PRK08248 |
homocysteine synthase; |
5-404 |
1.57e-36 |
|
homocysteine synthase;
Pssm-ID: 236201 [Multi-domain] Cd Length: 431 Bit Score: 139.59 E-value: 1.57e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 5 RLDTVVVNTGSQNDQHSAS-VPPVYLSTTFkVDLNNEDAQN--------YDYSRSGNPTRSVLQHQIGKLYRVPqeNVLA 75
Cdd:PRK08248 8 RLETLAIHAGQEIDPTTGSrAVPIYQTTSY-GFRDSEHAANlfslkefgNIYTRIMNPTTDVFEKRIAALEGGI--GALA 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 76 VSSGMTAldvILRGLVLLNGTDNHtptIIAGDDLYGGTQRLLnffkqqSH-----AVSVH-VDTSDFEKFKTVFQslDKV 149
Cdd:PRK08248 85 VSSGQAA---ITYSILNIASAGDE---IVSSSSLYGGTYNLF------AHtlpklGITVKfVDPSDPENFEAAIT--DKT 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 150 DCVLLESPTNPLCKVVDIPRILRFVKciSPDTTVVVDNTMMSGLNCNPLQLnpGCDVVYESATKYLNGHHDLMGGVIIS- 228
Cdd:PRK08248 151 KALFAETIGNPKGDVLDIEAVAAIAH--EHGIPLIVDNTFASPYLLRPIEH--GADIVVHSATKFIGGHGTSIGGVIVDs 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 229 --------------KTP----------EIASKLYFVINS-------TGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMIL 277
Cdd:PRK08248 227 gkfdwkgsgkfpglTEPdpsyhglvytDAVGEAAYITKArvqllrdLGAALSPFNSFLLLQGLETLHLRMERHSENALAV 306
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 278 AHWLENScgfkptrtNKATKTRFVGLRSNPDFKLHKSF-NNGPGAVLSFET-GSFEHSKRLVSSKKLsiWAVTVSFGCVN 355
Cdd:PRK08248 307 AKFLEEH--------EAVEWVSYPGLPSHPSYELAKKYlPKGQGAILTFGIkGGVEAGKKLIDSVKL--FSHLANVGDSK 376
|
410 420 430 440
....*....|....*....|....*....|....*....|....*....
gi 398364309 356 SLLSMPCKMSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAM 404
Cdd:PRK08248 377 SLIIHPASTTHQQLSEEEQLAAGVTPGLVRLSVGTEAIDDILDDLRQAI 425
|
|
| PRK08134 |
PRK08134 |
O-acetylhomoserine aminocarboxypropyltransferase; Validated |
5-404 |
2.48e-35 |
|
O-acetylhomoserine aminocarboxypropyltransferase; Validated
Pssm-ID: 236159 Cd Length: 433 Bit Score: 136.02 E-value: 2.48e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 5 RLDTVVVNTGSQND-QHSASVPPVYLSTTFKVD-------LNNEDAQNYDYSRSGNPTRSVLQHQIGKLyrvpqEN---V 73
Cdd:PRK08134 8 GFDTLALHAGAAPDpATGARAVPIHLTTSFVFRdsdhaaaLFNLERAGHVYSRISNPTVAVLEERVAAL-----EGgvgA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 74 LAVSSGMTALDVilrGLVLLNGTDNHtptIIAGDDLYGGTQRLLNFFKQQSHAVSVHVDTSDFEKFKTVFQSLDKVdcVL 153
Cdd:PRK08134 83 IATASGQAALHL---AIATLMGAGSH---IVASSALYGGSHNLLHYTLRRFGIETTFVKPGDIDGWRAAIRPNTRL--LF 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 154 LESPTNPLCKVVDIPRilrfVKCISPDTTV--VVDNTMMSGLNCNPLQLnpGCDVVYESATKYLNGHHDLMGGVIIS--- 228
Cdd:PRK08134 155 GETLGNPGLEVLDIPT----VAAIAHEAGVplLVDSTFTTPYLLRPFEH--GADLVYHSATKFLGGHGTAIGGVLVDggr 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 229 -------KTPEIAS------KLYFVINST----------------GAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAH 279
Cdd:PRK08134 229 fdweasgKFPELTEpyagfhGMVFAEESTvaafllrarreglrdfGACLSPMNAWQLLQGIETLPLRMERHVANTRKVVA 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 280 WLEnscgfkptrTNKAT-KTRFVGLRSNPDFKLHKS-FNNGPGAVLSFE-TGSFEHSKRLVSSkkLSIWAVTVSFGCVNS 356
Cdd:PRK08134 309 FLA---------SHPAVaRVAHPELESHPDHALAKRlLPRGAGSVFSFDlKGGRAAGRKFIES--LKLFSHLANVGDARS 377
|
410 420 430 440
....*....|....*....|....*....|....*....|....*...
gi 398364309 357 LLSMPCKMSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAM 404
Cdd:PRK08134 378 LVIHPASTTHFRMDAAALAAAGIGEGTIRLSIGLEDADDLIDDLKRAL 425
|
|
| PRK07812 |
PRK07812 |
O-acetylhomoserine aminocarboxypropyltransferase; Validated |
7-400 |
1.41e-33 |
|
O-acetylhomoserine aminocarboxypropyltransferase; Validated
Pssm-ID: 236105 Cd Length: 436 Bit Score: 131.41 E-value: 1.41e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 7 DTVVVNTGSQNDQHS-ASVPPVYLSTTFKVDLNNEDAQNYD-------YSRSGNPTRSVLQHQIGKLyrvpqEN---VLA 75
Cdd:PRK07812 15 ETKQIHAGQTPDPATnARALPIYQTTSYTFDDTDHAAALFGlaepgniYTRIMNPTQDVVEQRIAAL-----EGgvaALL 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 76 VSSGMTAldvilRGLVLLN--GTDNHtptIIAGDDLYGGTQRLLNF-FKQQSHAVSVHVDTSDFEKFKTVFQSLDKVdcV 152
Cdd:PRK07812 90 LASGQAA-----ETFAILNlaGAGDH---IVSSPRLYGGTYNLFHYtLPKLGIEVSFVEDPDDLDAWRAAVRPNTKA--F 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 153 LLESPTNPLCKVVDIPRilrfVKCISPDTTV--VVDNTMMSglncnPLQLNP---GCDVVYESATKYLNGHHDLMGGVII 227
Cdd:PRK07812 160 FAETISNPQIDVLDIPG----VAEVAHEAGVplIVDNTIAT-----PYLIRPlehGADIVVHSATKYLGGHGTAIAGVIV 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 228 S--------------KTP----------EIASKLYFV------INSTGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMIL 277
Cdd:PRK07812 231 DggtfdwtqgrfpgfTTPdpsyhgvvfaELGPPAYALkarvqlLRDLGSAISPFNAFLIAQGLETLSLRIERHVANAQRV 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 278 AHWLENScgfkptrtNKATKTRFVGLRSNPDFKLHKSFN-NGPGAVLSFE-TGSFEHSKRLVSSkkLSIWAVTVSFGCVN 355
Cdd:PRK07812 311 AEFLEAR--------DEVASVNYAGLPSSPWYERAKRLApKGTGAVLSFElAGGVEAGKAFVNA--LTLHSHVANIGDVR 380
|
410 420 430 440
....*....|....*....|....*....|....*....|....*
gi 398364309 356 SLLSMPCKMSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDL 400
Cdd:PRK07812 381 SLVIHPASTTHSQLTPEEQLATGVTPGLVRLAVGIEGIDDILADL 425
|
|
| PRK07049 |
PRK07049 |
cystathionine gamma-synthase family protein; |
25-404 |
2.94e-33 |
|
cystathionine gamma-synthase family protein;
Pssm-ID: 180809 [Multi-domain] Cd Length: 427 Bit Score: 130.18 E-value: 2.94e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 25 PPVYLSTTFKVDLNNEDAQNYD-----------------YSRSGNPTRSVLQHQIGKLYRVpqENVLAVSSGMTALDVIL 87
Cdd:PRK07049 38 PPVFLTSTFVFRSAEDGRDFFDyvsgrkeppagegaglvYSRFNHPNSEIVEDRLAVYEGA--ESAALFSSGMSAIATTL 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 88 rgLVLLNGTDnhtpTIIAGDDLYGGTQRLL-NFFKQ---QSHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCK 163
Cdd:PRK07049 116 --LAFVRPGD----VILHSQPLYGGTETLLaKTFRNfgvGAVGFADGLSEAAIGAAAEAAAAKGRVSLILIETPANPTNS 189
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 164 VVDIPRILRFVKCISPDT----TVVVDNTMMSGLNCNPLqlNPGCDVVYESATKYLNGHHDLM-GGVIISKtpEIASKLY 238
Cdd:PRK07049 190 LVDVAAVRRVADAIEARQghrpIIACDNTLLGPVFQKPL--EHGADLSVYSLTKYVGGHSDLVaGAVLGRK--ALIRQVR 265
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 239 FVINSTGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLenscgfkptRTN-KATKTRFVGLrSNPDFKLHKSFN- 316
Cdd:PRK07049 266 ALRSAIGTQLDPHSCWMLGRSLETLVLRMERANRNARAVAEFL---------RDHpKVEKLHYLPF-LDPDSAYGAVYKr 335
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 317 --NGPGAVLSFE-TGSFEHSKRLVSSkkLSIWAVTVSFGCVNSLLSMPCKMSHASIDPELRKERDFPEDLVRLCCGIENI 393
Cdd:PRK07049 336 qcTGAGSTFSFDiKGGQAAAFRFLNA--LQIFKLAVSLGGTESLASHPASMTHSGVPADVRERIGVLESTIRLSIGIEHP 413
|
410
....*....|.
gi 398364309 394 VDLKKDLLAAM 404
Cdd:PRK07049 414 DDLIADLAQAL 424
|
|
| PRK05968 |
PRK05968 |
hypothetical protein; Provisional |
22-407 |
1.06e-31 |
|
hypothetical protein; Provisional
Pssm-ID: 168320 [Multi-domain] Cd Length: 389 Bit Score: 125.19 E-value: 1.06e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 22 ASVPPVYLSTTFKVDLNNE-------DAQNYDYSRSGNPTRSVLQHQIGKLYRVpqENVLAVSSGMTALDVILrgLVLLN 94
Cdd:PRK05968 25 AVVPPIFQTSLFTFDSYDEmedvyagEKVRPIYSRGDNPTVRAFEEMLAKLEGA--EDARGFASGMAAISSTV--LSFVE 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 95 GTDNhtptIIAGDDLYGGTQRLLNFFKQQSHAVSVHVDTSDFEKfktVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFV 174
Cdd:PRK05968 101 PGDR----IVAVRHVYPDAFRLFETILKRMGVEVDYVDGRDEEA---VAKALPGAKLLYLESPTSWVFELQDVAALAALA 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 175 KciSPDTTVVVDNTMMSGLNCNPLQLnpGCDVVYESATKYLNGHHDLMGGVIISKTPEIASklyfvINS-----TGAGLS 249
Cdd:PRK05968 174 K--RHGVVTMIDNSWASPVFQRPITL--GVDLVIHSASKYLGGHSDTVAGVVAGSKEHIAR-----INAeaypyLGAKLS 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 250 PMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGfkptrtnkatktrfVGLRSNPDFKLH-KSFNNGPGAVLSFETG 328
Cdd:PRK05968 245 PFEAWLLLRGLRTLPLRMKAHEASALEIARRLKAHPV--------------VERVCHPALANHpPAGLSGTSGLFSFIFR 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 329 SFEHSKRLVSSKKLsiWAVTVSFGCVNSLLsMPCKMShASIDPELRKERDF--PEDLVRLCCGIENIVDLKKDLLAAMVD 406
Cdd:PRK05968 311 EGIDVRAFADALKL--FRLGVSWGGHESLV-VPAEVV-LQQKAQPNSAARFgvSPRSVRLHVGLEGTEALWADLEQALAA 386
|
.
gi 398364309 407 A 407
Cdd:PRK05968 387 A 387
|
|
| PRK05613 |
PRK05613 |
O-acetylhomoserine/O-acetylserine sulfhydrylase; |
8-400 |
1.79e-30 |
|
O-acetylhomoserine/O-acetylserine sulfhydrylase;
Pssm-ID: 168128 [Multi-domain] Cd Length: 437 Bit Score: 122.67 E-value: 1.79e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 8 TVVVNTGSQNdqhsasvPPVYLSTTFKVDLNNEDAQNYD-------YSRSGNPTRSVLQHQIGKLyrvpQENVLAV--SS 78
Cdd:PRK05613 24 SVDSDTSARN-------LPIYQTTSYVFDSAEHAKQRFAledlgpiYSRLTNPTVEALENRIASL----EGGVHAVafAS 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 79 GMTAldvILRGLVLLNGTDNHtptIIAGDDLYGGTQRLLNF-FKQQSHAVSVHVDTSDFEKFKTVFQslDKVDCVLLESP 157
Cdd:PRK05613 93 GQAA---ETAAILNLAGAGDH---IVTSPRLYGGTETLFLVtLNRLGIEVTFVENPDDPESWQAAVQ--PNTKAFFGETF 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 158 TNPLCKVVDIPRILRFVKciSPDTTVVVDNTMMSGLNCNPLQLnpGCDVVYESATKYLNGHHDLMGGVIISK-----TPE 232
Cdd:PRK05613 165 ANPQADVLDIPAVAEVAH--RNQVPLIVDNTIATAALVRPLEL--GADVVVASLTKFYTGNGSGLGGVLIDGgkfdwTVE 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 233 IASKLYF------------------------------VINSTGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLE 282
Cdd:PRK05613 241 RDGKPVFpyfvtpdpayhglkyadlgapafglkaragLLRDTGATLSPFNAWVTAQGLDTLSLRLERHNENAIKVAEFLN 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 283 NScgfkptrtNKATKTRFVGLRSNPDFKLHKSFN-NGPGAVLSFE-TGSFEHSKRLVSSKKLSiwAVTVSFGCVNSLLSM 360
Cdd:PRK05613 321 NH--------EKVAKVNFAGLKDSPWYATKEKLGlKYTGSVLSFDiKGGKDEAWAFIDALKLH--SNLANIGDVRSLVVH 390
|
410 420 430 440
....*....|....*....|....*....|....*....|
gi 398364309 361 PCKMSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDL 400
Cdd:PRK05613 391 PATTTHSQSDEAGLARAGITQATVRLSVGIEDIDDIIADL 430
|
|
| PRK06702 |
PRK06702 |
bifunctional O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase; |
8-405 |
5.08e-28 |
|
bifunctional O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase;
Pssm-ID: 102505 [Multi-domain] Cd Length: 432 Bit Score: 115.54 E-value: 5.08e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 8 TVVVNTGSQNDQHSASVPPVYLSTTFKVD-------LNNEDAQNYDYSRSGNPTRSVLQHQIGKLyrvpQENVLAVSSGM 80
Cdd:PRK06702 9 TICVQGGYTPKNGEPRVLPLYQSTTYKYDtsddlaaLFNLEAEGYIYTRIGNPTLAAFEQKLAEL----EGGVGAVATAS 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 81 TALDVILRGLVLLNGTDNhtptIIAGDDLYGGTqrlLNFFKQQSHAVSVHVD--TSDFEKFKTVFQSLDKVDCVLLESPT 158
Cdd:PRK06702 85 GQAAIMLAVLNICSSGDH----LLCSSTVYGGT---FNLFGVSLRKLGIDVTffNPNLTADEIVALANDKTKLVYAESLG 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 159 NPLCKVVDIPRILRFVKCIspDTTVVVDNTMMSGLNCNPLQlnPGCDVVYESATKYLNGHHDLMGGVIIS---------K 229
Cdd:PRK06702 158 NPAMNVLNFKEFSDAAKEL--EVPFIVDNTLATPYLCQAFE--HGANIIVHSTTKYIDGHASSLGGIVIDggnfdwtngK 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 230 TPEI----------------ASKLYFV------INSTGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLenscgf 287
Cdd:PRK06702 234 YPELvepdpsyhgvsyvqnfGAAAYIVkarvqlLRDYGNCMSPFNAYISNIGLETLHLRMERHSENALAVAKWL------ 307
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 288 kpTRTNKATKTRFVGLRSNPDFKL-HKSFNNGPGAVLSFE-TGSFEHSKRLVSSKKLSIWAVTVSFGcvNSLLSMPCKMS 365
Cdd:PRK06702 308 --ADHERIEWVNYPGLDSNENYSLaQKYLKKGASGVLTFGiKGGLEAAKEFIANVKLATLVTHVADA--RTCVIHPASTT 383
|
410 420 430 440
....*....|....*....|....*....|....*....|
gi 398364309 366 HASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMV 405
Cdd:PRK06702 384 HRQLSAEDQRLAGVTSDLIRLSVGIEDVSDIIADLEAALV 423
|
|
| PRK05939 |
PRK05939 |
cystathionine gamma-synthase family protein; |
19-404 |
1.55e-27 |
|
cystathionine gamma-synthase family protein;
Pssm-ID: 235650 [Multi-domain] Cd Length: 397 Bit Score: 113.63 E-value: 1.55e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 19 QHSASVPPVYLSTTFKVdlnnEDAQN-----------YDYSRSGNPTRSVLQHQIGKLyrvpQENVLAV--SSGMTALDV 85
Cdd:PRK05939 6 EHGAVHKPIHTSVTYGY----EDARDlidvfqgkkpgFTYARQGTPTTAALEAKITKM----EGGVGTVcfATGMAAIAA 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 86 ILrgLVLLNGTDNhtptIIAGDDLYGGTQRLLNFFKQQSHAVSVhVDTSDFEKFKTVFQSLDKVdcVLLESPTNPLCKVV 165
Cdd:PRK05939 78 VF--LTLLRAGDH----LVSSQFLFGNTNSLFGTLRGLGVEVTM-VDATDVQNVAAAIRPNTRM--VFVETIANPGTQVA 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 166 DIPRILRFvkCISPDTTVVVDNTMMSglncnPLQLNP---GCDVVYESATKYLNGHHDLMGGVII-------SKTPEIAS 235
Cdd:PRK05939 149 DLAGIGAL--CRERGLLYVVDNTMTS-----PWLFRPkdvGASLVINSLSKYIAGHGNALGGAVTdtglfdwSAYPNIFP 221
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 236 KlYFVINST---------------GAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENScgfkptrtNKATKTRF 300
Cdd:PRK05939 222 A-YRKGDPQqwgltqirkkglrdmGATLSSEAAHRIAIGAETLALRVDRSCSNALALAQFLEAH--------PKVARVYY 292
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 301 VGLRSNPDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSfgcVNSLLSMPckMSHA---SIDPELRKER 377
Cdd:PRK05939 293 PGLASHPQHARATELFRHYGGLLSFELADGIDCFDFLNRLKLVIKATHLG---DTRTLVIP--VAPTiyyEMGAERRASM 367
|
410 420
....*....|....*....|....*..
gi 398364309 378 DFPEDLVRLCCGIENIVDLKKDLLAAM 404
Cdd:PRK05939 368 GIADSLIRVSVGIEDEADLIADFEQAL 394
|
|
| PLN02242 |
PLN02242 |
methionine gamma-lyase |
45-390 |
1.11e-22 |
|
methionine gamma-lyase
Pssm-ID: 215134 Cd Length: 418 Bit Score: 99.84 E-value: 1.11e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 45 YDYSRSGNPTRSVLQHQIGKLYRVpqENVLAVSSGMTALDVILRGLVllnGTDNHtptIIAGDDLYGGTQRLL-NFFKQQ 123
Cdd:PLN02242 68 YIYSRHFNPTVLNLGRQMAALEGT--EAAYCTASGMSAISSVLLQLC---SSGGH---VVASNTLYGGTHALLaHFLPRK 139
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 124 SHAVSVHVDTSDFEKFKTVFQSlDKVDCVLLESPTNPLCKVVDIPRILRFVKciSPDTTVVVDNTMMsglncnPLQLNP- 202
Cdd:PLN02242 140 CNITTTFVDITDLEAVKKAVVP-GKTKVLYFESISNPTLTVADIPELARIAH--EKGVTVVVDNTFA------PMVLSPa 210
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 203 --GCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINST---GAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMIL 277
Cdd:PLN02242 211 rlGADVVVHSISKFISGGADIIAGAVCGPAELVNSMMDLHHGALmllGPTMNPKVAFELSERLPHLSLRMKEHCRRAMEY 290
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 278 AHWLEnSCGFKPTrtnkatktrFVGLRSNPDFKLHKSFNN---GPGAVLSFETGSFEHSKRLVssKKLSIWA----VTVS 350
Cdd:PLN02242 291 AKRMK-ELGLKVI---------YPGLEDHPQHALLKSMANkgyGFGGLLCLDMDTEERANRLM--RYLQNSTqfgfMAVS 358
|
330 340 350 360
....*....|....*....|....*....|....*....|
gi 398364309 351 FGCVNSLLSMPCKMSHASIDPELRKERDFPEDLVRLCCGI 390
Cdd:PLN02242 359 LGYYETLMSCSGSSTSSELDPEEKAAAGISPGLVRMSVGY 398
|
|
| PRK09028 |
PRK09028 |
cystathionine beta-lyase; Provisional |
151-403 |
3.50e-22 |
|
cystathionine beta-lyase; Provisional
Pssm-ID: 181615 [Multi-domain] Cd Length: 394 Bit Score: 97.88 E-value: 3.50e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 151 CVL-LESPTNPLCKVVDIPRILRFVKciSPDTTVVVDNTMMSGLNCNPLQLnpGCDVVYESATKYLNGHHDLMGGVIISK 229
Cdd:PRK09028 148 KVLfLESPGSITMEVQDVPTLSRIAH--EHDIVVMLDNTWASPINSRPFEM--GVDISIQAATKYIVGHSDVMLGTATAN 223
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 230 T---PEIASKLYFVinstGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENscgfKPtrtnKATKTRFVGLRSN 306
Cdd:PRK09028 224 EkhwDQLREHSYLM----GQCTSPDDVYLAMRGLRTLGVRLAQHEKNALKVANWLAT----RP----EVDHVRHPAFETC 291
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 307 PDFKLHKSFNNGPGAVLSF--ETGSFEHSKRLVSSkkLSIWAVTVSFGCVNSLLsmpckMSHASIDpELR--KERDFPED 382
Cdd:PRK09028 292 PGHEFFKRDFSGSNGLFSFvlKQGDPKAVTALVEG--MQHFKMGFSWGGFESLI-----LGVFGIN-KLRtaTNWDFSKP 363
|
250 260
....*....|....*....|.
gi 398364309 383 LVRLCCGIENIVDLKKDLLAA 403
Cdd:PRK09028 364 LIRLHIGLEDVDDLIADLEAG 384
|
|
| PRK08114 |
PRK08114 |
cystathionine beta-lyase; Provisional |
152-402 |
5.62e-21 |
|
cystathionine beta-lyase; Provisional
Pssm-ID: 181231 [Multi-domain] Cd Length: 395 Bit Score: 94.38 E-value: 5.62e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 152 VLLESPTNPLCKVVDIPRILRFVKCISPDTTVVVDNTMMSGLNCNPLQLnpGCDVVYESATKYLNGHHDLMGGVIISKT- 230
Cdd:PRK08114 151 VFLESPGSITMEVHDVPAIVAAVRSVNPDAVIMIDNTWAAGVLFKALDF--GIDISIQAGTKYLVGHSDAMIGTAVANAr 228
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 231 --PEIASKLYFVINSTGAGLSPMDSwllvRGLKTLGVRLYQQQRNAMILAHWLENscgfkptRTNKATktrfVGLRSNPD 308
Cdd:PRK08114 229 cwEQLRENSYLMGQMVDADTAYMTS----RGLRTLGVRLRQHEESSLKVAEWLAE-------HPEVAR----VNHPALPG 293
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 309 FKLHKSFN---NGPGAVLSFETgsfehSKRLvSSKKL-------SIWAVTVSFGCVNSLL--SMPCKMshASIDPELrkE 376
Cdd:PRK08114 294 CKGHEFWKrdfTGSSGLFSFVL-----KKKL-TDEQLanyldnfSLFSMAYSWGGFESLIlaNQPEEI--AAIRPAG--E 363
|
250 260
....*....|....*....|....*.
gi 398364309 377 RDFPEDLVRLCCGIENIVDLKKDLLA 402
Cdd:PRK08114 364 VDFTGTLIRLHIGLEDVDDLIADLAA 389
|
|
| PRK07050 |
PRK07050 |
cystathionine beta-lyase; Provisional |
152-404 |
1.02e-20 |
|
cystathionine beta-lyase; Provisional
Pssm-ID: 180810 [Multi-domain] Cd Length: 394 Bit Score: 93.64 E-value: 1.02e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 152 VLLESPTNPLCKVVDIPRILRFVKciSPDTTVVVDNTMMSGLNCNPLQLnpGCDVVYESATKYLNGHHDLMGGVIISKTP 231
Cdd:PRK07050 154 IWLEAPGSVTMEVPDVPAITAAAR--ARGVVTAIDNTYSAGLAFKPFEH--GVDISVQALTKYQSGGSDVLMGATITADA 229
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 232 EIASKLYFVINSTGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLEnscgfkpTRTNKATktrfVGLRSNPDFKL 311
Cdd:PRK07050 230 ELHAKLKLARMRLGIGVSADDCSLVLRGLPSLQVRLAAHDRSALEVAEWLK-------ARPEIAT----VLHPALPDCPG 298
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 312 HKSFN---NGPGAVLSF---ETGSFEHSKRLVSSkkLSIWAVTVSFGCVNSlLSMPCKMSHAsidpelrKERDFPED--L 383
Cdd:PRK07050 299 HAFWMrdfTGAGGLFSVvfdERYSPAQVDAFVEA--LELFAIGWSWGGACS-LAMPYDVASM-------RTAKWPHRgtL 368
|
250 260
....*....|....*....|.
gi 398364309 384 VRLCCGIENIVDLKKDLLAAM 404
Cdd:PRK07050 369 VRLYIGLEDEADLIADLEQAL 389
|
|
| PRK05967 |
PRK05967 |
cystathionine beta-lyase; Provisional |
42-407 |
1.08e-20 |
|
cystathionine beta-lyase; Provisional
Pssm-ID: 235657 [Multi-domain] Cd Length: 395 Bit Score: 93.72 E-value: 1.08e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 42 AQNYDYSRSGNPTRSVLQHQIGKLYrvPQENVLAVSSGMTALDVILRGLVllnGTDNHTPTIiagDDLYGGTQRLLNFFK 121
Cdd:PRK05967 53 GQKYTYGTRGTPTTDALCKAIDALE--GSAGTILVPSGLAAVTVPFLGFL---SPGDHALIV---DSVYYPTRHFCDTML 124
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 122 QQshaVSVHVDTSDFE---KFKTVFQSLDKVdcVLLESPTNPLCKVVDIPRILRFVKciSPDTTVVVDNTMMSGLNCNPL 198
Cdd:PRK05967 125 KR---LGVEVEYYDPEigaGIAKLMRPNTKV--VHTEAPGSNTFEMQDIPAIAEAAH--RHGAIVMMDNTWATPLYFRPL 197
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 199 QLnpGCDVVYESATKYLNGHHDLMGGVIiSKTPEIASKLYFVINSTGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILA 278
Cdd:PRK05967 198 DF--GVDISIHAATKYPSGHSDILLGTV-SANEKCWPQLLEAHGTLGLCAGPDDTYQILRGLRTMGIRLEHHRKSALEIA 274
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398364309 279 HWLENScgfkptrtNKATKTRFVGLRSNPDFKLHKSFNNGPGAVLSFE-TGSFEHSKRLVSS--KKLSIWAVTVSFGCVN 355
Cdd:PRK05967 275 RWLEGR--------PDVARVLHPALPSFPGHEIWKRDFSGASGIFSFVlAAGPEKGKAKAHAflDALEIFGLGYSWGGYE 346
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|..
gi 398364309 356 SLlsmpckMSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMVDA 407
Cdd:PRK05967 347 SL------ALHVKLGDRTVAKAPYAGPVIRLQIGLEDVPDLKADLERGFAAA 392
|
|
| |
