NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|118344454|ref|NP_004881|]
View 

sperm-associated antigen 7 [Homo sapiens]

Protein Classification

R3H_sperm-antigen domain-containing protein( domain architecture ID 10119027)

R3H_sperm-antigen domain-containing protein

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

Name Accession Description Interval E-value
R3H_sperm-antigen cd02636
R3H domain of a group of metazoan proteins that is related to the sperm-associated antigen 7. ...
49-109 1.29e-28

R3H domain of a group of metazoan proteins that is related to the sperm-associated antigen 7. The name of the R3H domain comes from the characteristic spacing of the most conserved arginine and histidine residues. The function of the domain is predicted to bind ssDNA or ssRNA in a sequence-specific manner.


:

Pssm-ID: 100065  Cd Length: 61  Bit Score: 102.41  E-value: 1.29e-28
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 118344454  49 RKRMEKEVSDFIQDSGQIKKKFQPMNKIERSILHDVVEVAGLTSFSFGEDDDCRYVMIFKK 109
Cdd:cd02636    1 RKSMEKEVSKFIKDSVRTREKFQPMDKVERSIVHDVAEVAGLTSFSFGEDEVDRYVMIFKK 61
 
Name Accession Description Interval E-value
R3H_sperm-antigen cd02636
R3H domain of a group of metazoan proteins that is related to the sperm-associated antigen 7. ...
49-109 1.29e-28

R3H domain of a group of metazoan proteins that is related to the sperm-associated antigen 7. The name of the R3H domain comes from the characteristic spacing of the most conserved arginine and histidine residues. The function of the domain is predicted to bind ssDNA or ssRNA in a sequence-specific manner.


Pssm-ID: 100065  Cd Length: 61  Bit Score: 102.41  E-value: 1.29e-28
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 118344454  49 RKRMEKEVSDFIQDSGQIKKKFQPMNKIERSILHDVVEVAGLTSFSFGEDDDCRYVMIFKK 109
Cdd:cd02636    1 RKSMEKEVSKFIKDSVRTREKFQPMDKVERSIVHDVAEVAGLTSFSFGEDEVDRYVMIFKK 61
R3H pfam01424
R3H domain; The name of the R3H domain comes from the characteriztic spacing of the most ...
47-108 7.38e-14

R3H domain; The name of the R3H domain comes from the characteriztic spacing of the most conserved arginine and histidine residues. The function of the domain is predicted to be binding ssDNA.


Pssm-ID: 460206  Cd Length: 60  Bit Score: 64.05  E-value: 7.38e-14
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 118344454   47 EFRKRMEKEVSDFIQDSGQiKKKFQPMNKIERSILHDVVEVAGLTSFSFGEDDDcRYVMIFK 108
Cdd:pfam01424   1 EFLEQLAEKLAEFVKDTGK-SLELPPMSSYERRIIHELAQKYGLESESEGEEPN-RRVVVYK 60
R3H smart00393
Putative single-stranded nucleic acids-binding domain;
31-109 3.75e-13

Putative single-stranded nucleic acids-binding domain;


Pssm-ID: 214647  Cd Length: 79  Bit Score: 62.70  E-value: 3.75e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118344454    31 AARLKKLQEQEKQqKVEFRKRMEKEVSDFIQ--DSGQIKKKFQPMNKIERSILHDVVEVAGLTSFSFGEDDDcRYVMIFK 108
Cdd:smart00393   1 ADFLPVTLDALSY-RPRRREELIELELEIARfvKSTKESVELPPMNSYERKIVHELAEKYGLESESFGEGPK-RRVVISK 78

                   .
gi 118344454   109 K 109
Cdd:smart00393  79 K 79
Jag COG1847
Predicted RNA-binding protein Jag (SpoIIIJ-associated), conains KH and R3H domains [General ...
50-110 2.54e-03

Predicted RNA-binding protein Jag (SpoIIIJ-associated), conains KH and R3H domains [General function prediction only];


Pssm-ID: 441452 [Multi-domain]  Cd Length: 143  Bit Score: 37.01  E-value: 2.54e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 118344454  50 KRMEKEVSDFIQDSGQiKKKFQPMNKIERSILHDVV-EVAGLTSFSFGEDDDcRYVMIFKKE 110
Cdd:COG1847   84 EELARRAAEKVKRTGK-PVELEPMSPYERRIIHDALaDDPGVETESEGEEPY-RRVVISPKR 143
 
Name Accession Description Interval E-value
R3H_sperm-antigen cd02636
R3H domain of a group of metazoan proteins that is related to the sperm-associated antigen 7. ...
49-109 1.29e-28

R3H domain of a group of metazoan proteins that is related to the sperm-associated antigen 7. The name of the R3H domain comes from the characteristic spacing of the most conserved arginine and histidine residues. The function of the domain is predicted to bind ssDNA or ssRNA in a sequence-specific manner.


Pssm-ID: 100065  Cd Length: 61  Bit Score: 102.41  E-value: 1.29e-28
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 118344454  49 RKRMEKEVSDFIQDSGQIKKKFQPMNKIERSILHDVVEVAGLTSFSFGEDDDCRYVMIFKK 109
Cdd:cd02636    1 RKSMEKEVSKFIKDSVRTREKFQPMDKVERSIVHDVAEVAGLTSFSFGEDEVDRYVMIFKK 61
R3H pfam01424
R3H domain; The name of the R3H domain comes from the characteriztic spacing of the most ...
47-108 7.38e-14

R3H domain; The name of the R3H domain comes from the characteriztic spacing of the most conserved arginine and histidine residues. The function of the domain is predicted to be binding ssDNA.


Pssm-ID: 460206  Cd Length: 60  Bit Score: 64.05  E-value: 7.38e-14
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 118344454   47 EFRKRMEKEVSDFIQDSGQiKKKFQPMNKIERSILHDVVEVAGLTSFSFGEDDDcRYVMIFK 108
Cdd:pfam01424   1 EFLEQLAEKLAEFVKDTGK-SLELPPMSSYERRIIHELAQKYGLESESEGEEPN-RRVVVYK 60
R3H cd02325
R3H domain. The name of the R3H domain comes from the characteristic spacing of the most ...
49-108 2.47e-13

R3H domain. The name of the R3H domain comes from the characteristic spacing of the most conserved arginine and histidine residues. R3H domains are found in proteins together with ATPase domains, SF1 helicase domains, SF2 DEAH helicase domains, Cys-rich repeats, ring-type zinc fingers, and KH domains. The function of the domain is predicted to bind ssDNA or ssRNA in a sequence-specific manner.


Pssm-ID: 100064  Cd Length: 59  Bit Score: 62.63  E-value: 2.47e-13
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 118344454  49 RKRMEKEVSDFIQDSGQIKKKFQPMNKIERSILHDVVEVAGLTSFSFGEDDDcRYVMIFK 108
Cdd:cd02325    1 REEREEELEAFAKDAAGKSLELPPMNSYERKLIHDLAEYYGLKSESEGEGPN-RRVVITK 59
R3H smart00393
Putative single-stranded nucleic acids-binding domain;
31-109 3.75e-13

Putative single-stranded nucleic acids-binding domain;


Pssm-ID: 214647  Cd Length: 79  Bit Score: 62.70  E-value: 3.75e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118344454    31 AARLKKLQEQEKQqKVEFRKRMEKEVSDFIQ--DSGQIKKKFQPMNKIERSILHDVVEVAGLTSFSFGEDDDcRYVMIFK 108
Cdd:smart00393   1 ADFLPVTLDALSY-RPRRREELIELELEIARfvKSTKESVELPPMNSYERKIVHELAEKYGLESESFGEGPK-RRVVISK 78

                   .
gi 118344454   109 K 109
Cdd:smart00393  79 K 79
R3H_encore_like cd02642
R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the ...
51-108 4.54e-06

R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H domain is a potential regulator of DBF1 activity in stress responses. The name of the R3H domain comes from the characteristic spacing of the most conserved arginine and histidine residues. The function of the domain is predicted to bind ssDNA or ssRNA in a sequence-specific manner.


Pssm-ID: 100071  Cd Length: 63  Bit Score: 42.97  E-value: 4.54e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 118344454  51 RMEKEVSDFIQDSGQIKKKFQPMNKIERSILHDVVEVAGLTSFSFGEDDDCryVMIFK 108
Cdd:cd02642    7 KLEKDLLAFIKDSTRQSLELPPMNSYYRLLAHRVAQYYGLDHNVDNSGGKC--VIVNK 62
Jag COG1847
Predicted RNA-binding protein Jag (SpoIIIJ-associated), conains KH and R3H domains [General ...
50-110 2.54e-03

Predicted RNA-binding protein Jag (SpoIIIJ-associated), conains KH and R3H domains [General function prediction only];


Pssm-ID: 441452 [Multi-domain]  Cd Length: 143  Bit Score: 37.01  E-value: 2.54e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 118344454  50 KRMEKEVSDFIQDSGQiKKKFQPMNKIERSILHDVV-EVAGLTSFSFGEDDDcRYVMIFKKE 110
Cdd:COG1847   84 EELARRAAEKVKRTGK-PVELEPMSPYERRIIHDALaDDPGVETESEGEEPY-RRVVISPKR 143
R3H_unknown_2 cd06006
R3H domain of a group of fungal proteins with unknown function. The name of the R3H domain ...
51-108 8.22e-03

R3H domain of a group of fungal proteins with unknown function. The name of the R3H domain comes from the characteristic spacing of the most conserved arginine and histidine residues. The function of the domain is predicted to bind ssDNA or ssRNA in a sequence-specific manner.


Pssm-ID: 100076  Cd Length: 59  Bit Score: 33.88  E-value: 8.22e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 118344454  51 RMEKEVSDFIQDSGQIKKKFQPMNKIERSILHDVVEVAGLTSFSFgEDDDCRYVMIFK 108
Cdd:cd06006    3 QIESTLRKFINDKSKRSLRFPPMRSPQRAFIHELAKDYGLYSESQ-DPEPKRSVFVKK 59
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH