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Conserved domains on  [gi|4502857|ref|NP_001817|]
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cyclin-dependent kinases regulatory subunit 1 [Homo sapiens]

Protein Classification

cyclin-dependent kinases regulatory subunit( domain architecture ID 10471449)

cyclin-dependent kinases regulatory subunit binds to the catalytic subunit of cyclin dependent kinases and is essential for their biological function

CATH:  3.30.170.10
Gene Ontology:  GO:0016538
PubMed:  25864384
SCOP:  4001729

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CKS pfam01111
Cyclin-dependent kinase regulatory subunit;
6-73 3.93e-45

Cyclin-dependent kinase regulatory subunit;


:

Pssm-ID: 460068  Cd Length: 68  Bit Score: 138.83  E-value: 3.93e-45
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 4502857     6 IYYSDKYDDEEFEYRHVMLPKDIAKLVPKTHLMSESEWRNLGVQQSQGWVHYMIHEPEPHILLFRRPL 73
Cdd:pfam01111  1 IYYSDKYEDDEYEYRHVILPKELAKKIPKNRLLTEEEWRNLGIQQSPGWEHYMIHKPEPHILLFRRPK 68
 
Name Accession Description Interval E-value
CKS pfam01111
Cyclin-dependent kinase regulatory subunit;
6-73 3.93e-45

Cyclin-dependent kinase regulatory subunit;


Pssm-ID: 460068  Cd Length: 68  Bit Score: 138.83  E-value: 3.93e-45
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 4502857     6 IYYSDKYDDEEFEYRHVMLPKDIAKLVPKTHLMSESEWRNLGVQQSQGWVHYMIHEPEPHILLFRRPL 73
Cdd:pfam01111  1 IYYSDKYEDDEYEYRHVILPKELAKKIPKNRLLTEEEWRNLGIQQSPGWEHYMIHKPEPHILLFRRPK 68
CKS smart01084
Cyclin-dependent kinase regulatory subunit; Cyclin-dependent kinase regulatory subunit.
 5-74 7.24e-39

Cyclin-dependent kinase regulatory subunit; Cyclin-dependent kinase regulatory subunit.


Pssm-ID: 198152  Cd Length: 70  Bit Score: 123.22  E-value: 7.24e-39
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502857      5 QIYYSDKYDDEEFEYRHVMLPKDIAKLVPKTHLMSESEWRNLGVQQSQGWVHYMIHEPEPHILLFRRPLP 74
Cdd:smart01084  1 PIYYSDKYEDDEYEYRHVILPKEIAKLVPKIRLLSENEWRKLGIQQSKGWEHYMIHKPEPHILLFRRPLN 70
PLN00010 PLN00010
cyclin-dependent kinases regulatory subunit; Provisional
 5-79 2.12e-37

cyclin-dependent kinases regulatory subunit; Provisional


Pssm-ID: 215027  Cd Length: 86  Bit Score: 120.04  E-value: 2.12e-37
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 4502857    5 QIYYSDKYDDEEFEYRHVMLPKDIAKLVPKTHLMSESEWRNLGVQQSQGWVHYMIHEPEPHILLFRRPLPKKPKK 79
Cdd:PLN00010  3 QIQYSEKYFDDTYEYRHVVLPPEVAKLLPKNRLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLNYQQQQ 77
 
Name Accession Description Interval E-value
CKS pfam01111
Cyclin-dependent kinase regulatory subunit;
6-73 3.93e-45

Cyclin-dependent kinase regulatory subunit;


Pssm-ID: 460068  Cd Length: 68  Bit Score: 138.83  E-value: 3.93e-45
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 4502857     6 IYYSDKYDDEEFEYRHVMLPKDIAKLVPKTHLMSESEWRNLGVQQSQGWVHYMIHEPEPHILLFRRPL 73
Cdd:pfam01111  1 IYYSDKYEDDEYEYRHVILPKELAKKIPKNRLLTEEEWRNLGIQQSPGWEHYMIHKPEPHILLFRRPK 68
CKS smart01084
Cyclin-dependent kinase regulatory subunit; Cyclin-dependent kinase regulatory subunit.
 5-74 7.24e-39

Cyclin-dependent kinase regulatory subunit; Cyclin-dependent kinase regulatory subunit.


Pssm-ID: 198152  Cd Length: 70  Bit Score: 123.22  E-value: 7.24e-39
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4502857      5 QIYYSDKYDDEEFEYRHVMLPKDIAKLVPKTHLMSESEWRNLGVQQSQGWVHYMIHEPEPHILLFRRPLP 74
Cdd:smart01084  1 PIYYSDKYEDDEYEYRHVILPKEIAKLVPKIRLLSENEWRKLGIQQSKGWEHYMIHKPEPHILLFRRPLN 70
PLN00010 PLN00010
cyclin-dependent kinases regulatory subunit; Provisional
 5-79 2.12e-37

cyclin-dependent kinases regulatory subunit; Provisional


Pssm-ID: 215027  Cd Length: 86  Bit Score: 120.04  E-value: 2.12e-37
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 4502857    5 QIYYSDKYDDEEFEYRHVMLPKDIAKLVPKTHLMSESEWRNLGVQQSQGWVHYMIHEPEPHILLFRRPLPKKPKK 79
Cdd:PLN00010  3 QIQYSEKYFDDTYEYRHVVLPPEVAKLLPKNRLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLNYQQQQ 77
PTZ00453 PTZ00453
cyclin-dependent kinase; Provisional
 5-72 1.11e-36

cyclin-dependent kinase; Provisional


Pssm-ID: 185632  Cd Length: 96  Bit Score: 118.52  E-value: 1.11e-36
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 4502857    5 QIYYSDKYDDEEFEYRHVMLPKDIAKLVPKTHLMSESEWRNLGVQQSQGWVHYMIHEPEPHILLFRRP 72
Cdd:PTZ00453 27 KILYSDKYYDDEYEYRHVILPKDFARLVPRSRLMSESEWRQLGVQQSVGWRHYMIHKPEPHVLLFKRP 94
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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