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Conserved domains on  [gi|2175849734|ref|NP_001386428|]
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tetratricopeptide repeat protein 8 isoform 3 [Rattus norvegicus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TTC8_N cd21341
N-terminal domain of tetratricopeptide repeat domain 8; Tetratricopeptide repeat domain 8 ...
 30-179 8.08e-86

N-terminal domain of tetratricopeptide repeat domain 8; Tetratricopeptide repeat domain 8 (TTC80), also known a BBS8, has been directly linked to Bardet-Biedl syndrome, an autosomal recessive ciliopathy characterized by retinal degeneration, renal failure, obesity, diabetes, male infertility, polydactyly and cognitive impairment. Mutations in BBS8 cause early vision loss. In addition to C-terminal tetratricopeptide repeats, TTC8 also contains an N-terminal domain of unknown function.


:

Pssm-ID: 411061 [Multi-domain]  Cd Length: 139  Bit Score: 260.70  E-value: 8.08e-86
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734  30 MLEKSPYDQdpapdlavsqAAWILKARALTEMVYVDEIDVDQEGIAEMTLDENAIAQVPRPGTSLKLPGTNQtGGPTQAV 109
Cdd:cd21341     1 LLEKNPYDQ----------AAWFLKMRALTEQVYIDDTEVDEEGIAELLMDENVIATVPRPGTSLRRPTTSA-GGPSQAM 69

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 110 RPITQAGRPITGFLRPSTQSGRPGTMEQAIRTPRTAYTARPITSSSGRFVRLGTASMLTSPDGPFINLSR 179
Cdd:cd21341    70 RPTTSSGRPITGFVRPGTQSGRPGTSRQALRTPRRAGTARPVTSASGRFVRLGTASMLSGPDGPFINVSR 139
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 232-511 2.84e-23

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 99.42  E-value: 2.84e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 232 GKCYYRLGMYREAEKQFKSALKQ-QEMVDTFLYLAKVYIILDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNNSSS 310
Cdd:COG2956    15 GLNYLLNGQPDKAIDLLEEALELdPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDR 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 311 AAEYYKEVLKQDNTHVEAIACIGSNHFYSDQPEVALRFYRRLLQMGVYNCQLFNNLGLCCFYAQQYDMTLTSFERALSLA 390
Cdd:COG2956    95 AEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLD 174

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 391 ENeeeAADVWYNLGHIAVGIGDTNLAHQCFRLALVHNNHHAEAYNNLAVLEMRKGHIEQARALLQTASSLAPHmyephfn 470
Cdd:COG2956   175 PD---CARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPS------- 244

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|.
gi 2175849734 471 fatvSDKIGDLQRSYVAAQKSEAAfpehvdTQHLIKQLKQH 511
Cdd:COG2956   245 ----DDLLLALADLLERKEGLEAA------LALLERQLRRH 275
 
Name Accession Description Interval E-value
TTC8_N cd21341
N-terminal domain of tetratricopeptide repeat domain 8; Tetratricopeptide repeat domain 8 ...
 30-179 8.08e-86

N-terminal domain of tetratricopeptide repeat domain 8; Tetratricopeptide repeat domain 8 (TTC80), also known a BBS8, has been directly linked to Bardet-Biedl syndrome, an autosomal recessive ciliopathy characterized by retinal degeneration, renal failure, obesity, diabetes, male infertility, polydactyly and cognitive impairment. Mutations in BBS8 cause early vision loss. In addition to C-terminal tetratricopeptide repeats, TTC8 also contains an N-terminal domain of unknown function.


Pssm-ID: 411061 [Multi-domain]  Cd Length: 139  Bit Score: 260.70  E-value: 8.08e-86
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734  30 MLEKSPYDQdpapdlavsqAAWILKARALTEMVYVDEIDVDQEGIAEMTLDENAIAQVPRPGTSLKLPGTNQtGGPTQAV 109
Cdd:cd21341     1 LLEKNPYDQ----------AAWFLKMRALTEQVYIDDTEVDEEGIAELLMDENVIATVPRPGTSLRRPTTSA-GGPSQAM 69

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 110 RPITQAGRPITGFLRPSTQSGRPGTMEQAIRTPRTAYTARPITSSSGRFVRLGTASMLTSPDGPFINLSR 179
Cdd:cd21341    70 RPTTSSGRPITGFVRPGTQSGRPGTSRQALRTPRRAGTARPVTSASGRFVRLGTASMLSGPDGPFINVSR 139
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 232-511 2.84e-23

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 99.42  E-value: 2.84e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 232 GKCYYRLGMYREAEKQFKSALKQ-QEMVDTFLYLAKVYIILDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNNSSS 310
Cdd:COG2956    15 GLNYLLNGQPDKAIDLLEEALELdPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDR 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 311 AAEYYKEVLKQDNTHVEAIACIGSNHFYSDQPEVALRFYRRLLQMGVYNCQLFNNLGLCCFYAQQYDMTLTSFERALSLA 390
Cdd:COG2956    95 AEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLD 174

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 391 ENeeeAADVWYNLGHIAVGIGDTNLAHQCFRLALVHNNHHAEAYNNLAVLEMRKGHIEQARALLQTASSLAPHmyephfn 470
Cdd:COG2956   175 PD---CARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPS------- 244

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|.
gi 2175849734 471 fatvSDKIGDLQRSYVAAQKSEAAfpehvdTQHLIKQLKQH 511
Cdd:COG2956   245 ----DDLLLALADLLERKEGLEAA------LALLERQLRRH 275
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 230-463 8.57e-09

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 58.17  E-value: 8.57e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 230 QIGKCYYRLGMYREAEKQFKSALKQQ-EMVDTFLYLAKVYIILDQPVTAL------------------------------ 278
Cdd:TIGR02917  61 LLGKIYLALGDYAAAEKELRKALSLGyPKNQVLPLLARAYLLQGKFQQVLdelpgktllddegaaellalrglaylglgq 140

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 279 -----NLFKQGLDKFPGEVTLLCGIARIYEEMNNSSSAAEYYKEVLKQDNTHVEAIACIGSNHFYSDQPEVALRFYRRLL 353
Cdd:TIGR02917 141 lelaqKSYEQALAIDPRSLYAKLGLAQLALAENRFDEARALIDEVLTADPGNVDALLLKGDLLLSLGNIELALAAYRKAI 220

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 354 QMGVYNCQLFNNLGLCCFYAQQYDMTLTSFERALSLAENEEEAAdvwYNLGHIAVGIGDTNLAHQCFRLALVHNNHHAEA 433
Cdd:TIGR02917 221 ALRPNNIAVLLALATILIEAGEFEEAEKHADALLKKAPNSPLAH---YLKALVDFQKKNYEDARETLQDALKSAPEYLPA 297

                         250       260       270
                  ....*....|....*....|....*....|
gi 2175849734 434 YNNLAVLEMRKGHIEQARALLQTASSLAPH 463
Cdd:TIGR02917 298 LLLAGASEYQLGNLEQAYQYLNQILKYAPN 327
TPR_12 pfam13424
Tetratricopeptide repeat;
360-424 2.29e-04

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 39.68  E-value: 2.29e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 360 CQLFNNLGLCCFYAQQYDMTLTSFERALSLAENE-----EEAADVWYNLGHIAVGIGDTNLAHQCFRLAL 424
Cdd:pfam13424   3 ATALNNLAAVLRRLGRYDEALELLEKALEIARRLlgpdhPLTATTLLNLGRLYLELGRYEEALELLERAL 72
LPA1 PLN03098
LOW PSII ACCUMULATION1; Provisional
 365-424 4.53e-03

LOW PSII ACCUMULATION1; Provisional


Pssm-ID: 215573 [Multi-domain]  Cd Length: 453  Bit Score: 39.49  E-value: 4.53e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 365 NLGLCCFYAQQYDMTLTSFERALSLAENEEEAADVWYNLGHIAVGIGDTNLAHQCFRLAL 424
Cdd:PLN03098   80 NLGLSLFSKGRVKDALAQFETALELNPNPDEAQAAYYNKACCHAYREEGKKAADCLRTAL 139
 
Name Accession Description Interval E-value
TTC8_N cd21341
N-terminal domain of tetratricopeptide repeat domain 8; Tetratricopeptide repeat domain 8 ...
 30-179 8.08e-86

N-terminal domain of tetratricopeptide repeat domain 8; Tetratricopeptide repeat domain 8 (TTC80), also known a BBS8, has been directly linked to Bardet-Biedl syndrome, an autosomal recessive ciliopathy characterized by retinal degeneration, renal failure, obesity, diabetes, male infertility, polydactyly and cognitive impairment. Mutations in BBS8 cause early vision loss. In addition to C-terminal tetratricopeptide repeats, TTC8 also contains an N-terminal domain of unknown function.


Pssm-ID: 411061 [Multi-domain]  Cd Length: 139  Bit Score: 260.70  E-value: 8.08e-86
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734  30 MLEKSPYDQdpapdlavsqAAWILKARALTEMVYVDEIDVDQEGIAEMTLDENAIAQVPRPGTSLKLPGTNQtGGPTQAV 109
Cdd:cd21341     1 LLEKNPYDQ----------AAWFLKMRALTEQVYIDDTEVDEEGIAELLMDENVIATVPRPGTSLRRPTTSA-GGPSQAM 69

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 110 RPITQAGRPITGFLRPSTQSGRPGTMEQAIRTPRTAYTARPITSSSGRFVRLGTASMLTSPDGPFINLSR 179
Cdd:cd21341    70 RPTTSSGRPITGFVRPGTQSGRPGTSRQALRTPRRAGTARPVTSASGRFVRLGTASMLSGPDGPFINVSR 139
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 232-511 2.84e-23

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 99.42  E-value: 2.84e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 232 GKCYYRLGMYREAEKQFKSALKQ-QEMVDTFLYLAKVYIILDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNNSSS 310
Cdd:COG2956    15 GLNYLLNGQPDKAIDLLEEALELdPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDR 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 311 AAEYYKEVLKQDNTHVEAIACIGSNHFYSDQPEVALRFYRRLLQMGVYNCQLFNNLGLCCFYAQQYDMTLTSFERALSLA 390
Cdd:COG2956    95 AEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLD 174

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 391 ENeeeAADVWYNLGHIAVGIGDTNLAHQCFRLALVHNNHHAEAYNNLAVLEMRKGHIEQARALLQTASSLAPHmyephfn 470
Cdd:COG2956   175 PD---CARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPS------- 244

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|.
gi 2175849734 471 fatvSDKIGDLQRSYVAAQKSEAAfpehvdTQHLIKQLKQH 511
Cdd:COG2956   245 ----DDLLLALADLLERKEGLEAA------LALLERQLRRH 275
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 261-511 4.45e-21

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 93.26  E-value: 4.45e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 261 FLYLAKVYIILDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNNSSSAAEYYKEVLKQDNTHVEAIACIGSNHFYSD 340
Cdd:COG2956    11 WYFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAG 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 341 QPEVALRFYRRLLQMGVYNCQLFNNLGLCCFYAQQYDMTLTSFERALSLAENEeeaADVWYNLGHIAVGIGDTNLAHQCF 420
Cdd:COG2956    91 LLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPEN---AHAYCELAELYLEQGDYDEAIEAL 167

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 421 RLALVHNNHHAEAYNNLAVLEMRKGHIEQARALLQTASSLAPHMYEPHFNFATVSDKIGDLQRSYVAAQKSEAAFPEHVD 500
Cdd:COG2956   168 EKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSDDL 247

                         250
                  ....*....|.
gi 2175849734 501 TQHLIKQLKQH 511
Cdd:COG2956   248 LLALADLLERK 258
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
289-457 5.04e-21

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 92.38  E-value: 5.04e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 289 PGEVTLLCGIARIYEEMNNSSSAAEYYKEVLKQDNTHVEAIACIGSNHFYSDQPEVALRFYRRLLQMGVYNCQLFNNLGL 368
Cdd:COG0457     5 PDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGL 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 369 CCFYAQQYDMTLTSFERALSLAENEeeaADVWYNLGHIAVGIGDTNLAHQCFRLALVHNNHHAEAYNNLAVLEMRKGHIE 448
Cdd:COG0457    85 ALQALGRYEEALEDYDKALELDPDD---AEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYE 161


                  ....*....
gi 2175849734 449 QARALLQTA 457
Cdd:COG0457   162 EALELLEKL 170
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
319-494 1.60e-18

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 85.06  E-value: 1.60e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 319 LKQDNTHVEAIACIGSNHFYSDQPEVALRFYRRLLQMGVYNCQLFNNLGLCCFYAQQYDMTLTSFERALSLaenEEEAAD 398
Cdd:COG0457     1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALEL---DPDDAE 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 399 VWYNLGHIAVGIGDTNLAHQCFRLALVHNNHHAEAYNNLAVLEMRKGHIEQARALLQTASSLAPHMYEPHFNFATVSDKI 478
Cdd:COG0457    78 ALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKL 157

                         170
                  ....*....|....*.
gi 2175849734 479 GDLQRSYVAAQKSEAA 494
Cdd:COG0457   158 GRYEEALELLEKLEAA 173
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
256-457 2.46e-18

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 84.29  E-value: 2.46e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 256 EMVDTFLYLAKVYIILDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNNSSSAAEYYKEVLKQDNTHVEAIACIGSN 335
Cdd:COG0457     6 DDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLA 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 336 HFYSDQPEVALRFYRRLLQMGVYNCQLFNNLGLCCFYAQQYDMTLTSFERALSLAENEEEAadvWYNLGHIAVGIGDTNL 415
Cdd:COG0457    86 LQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADA---LYNLGIALEKLGRYEE 162

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 2175849734 416 AHQCF-RLALVHNNHHAEAYNNLAVLEMRKGHIEQARALLQTA 457
Cdd:COG0457   163 ALELLeKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQ 205
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 230-457 4.66e-17

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 81.31  E-value: 4.66e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 230 QIGKCYYRLGMYREAEKQFKSALKQQEMVDTFLY-LAKVYIILDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNNS 308
Cdd:COG2956    47 ALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLeLAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDW 126

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 309 SSAAEYYKEVLKQDNTHVEAIACIGSNHFYSDQPEVALRFYRRLLQMGVYNCQLFNNLGLCCFYAQQYDMTLTSFERALs 388
Cdd:COG2956   127 EKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERAL- 205

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2175849734 389 laENEEEAADVWYNLGHIAVGIGDTNLAHQCFRlALVHNNHHAEAYNNLAVLEMRKGHIEQARALLQTA 457
Cdd:COG2956   206 --EQDPDYLPALPRLAELYEKLGDPEEALELLR-KALELDPSDDLLLALADLLERKEGLEAALALLERQ 271
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
231-455 6.35e-17

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 80.44  E-value: 6.35e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 231 IGKCYYRLGMYREAEKQFKSALK-QQEMVDTFLYLAKVYIILDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNNSS 309
Cdd:COG0457    14 LGLAYRRLGRYEEAIEDYEKALElDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYE 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 310 SAAEYYKEVLKQDNTHVEAIACIGSNHFYSDQPEVALRFYRRLLQMGVYNCQLFNNLGLCCFYAQQYDMTLTSFERALSL 389
Cdd:COG0457    94 EALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEAA 173

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2175849734 390 AENEEEAADVWYNLGHIAVGIGDTNLAHQCFRLALVHNNHHAEAYNNLAVLEMRKGHIEQARALLQ 455
Cdd:COG0457   174 ALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALALLLALRLAALA 239
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 229-427 7.89e-17

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 80.54  E-value: 7.89e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 229 VQIGKCYYRLGMYREAEKQFKSALKQQEM-VDTFLYLAKVYIILDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNN 307
Cdd:COG2956    80 LELAQDYLKAGLLDRAEELLEKLLELDPDdAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGD 159

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 308 SSSAAEYYKEVLKQDNTHVEAIACIGSNHFYSDQPEVALRFYRRLLQMGVYNCQLFNNLGLCCFYAQQYDMTLTSFERAL 387
Cdd:COG2956   160 YDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKAL 239

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 2175849734 388 SLAENeeeaADVWYNLGHIAVGIGDTNLAHQCFRLALVHN 427
Cdd:COG2956   240 ELDPS----DDLLLALADLLERKEGLEAALALLERQLRRH 275
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
353-503 1.87e-16

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 78.90  E-value: 1.87e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 353 LQMGVYNCQLFNNLGLCCFYAQQYDMTLTSFERALSLAENEEEAadvWYNLGHIAVGIGDTNLAHQCFRLALVHNNHHAE 432
Cdd:COG0457     1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEA---LYNLGLAYLRLGRYEEALADYEQALELDPDDAE 77

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2175849734 433 AYNNLAVLEMRKGHIEQARALLQTASSLAPHMYEPHFNFATVSDKIGDLQRSYVAAQKSEAAFPEHVDTQH 503
Cdd:COG0457    78 ALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALY 148
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 373-505 1.08e-15

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 80.04  E-value: 1.08e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 373 AQQYDMTLTSFERALSLAENEeeaADVWYNLGHIAVGIGDTNLAHQCFRLALVHNNHHAEAYNNLAVLEMRKGHIEQARA 452
Cdd:COG3914    91 LGRYEEALALYRRALALNPDN---AEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIA 167

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2175849734 453 LLQTASSLAPHMYEPHFNFATVSDKIGDLQRSYVAAQKSEAAFPEHVDTQHLI 505
Cdd:COG3914   168 ALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNL 220
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 230-355 1.19e-13

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 67.91  E-value: 1.19e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 230 QIGKCYYRLGMYREAEKQFKSALKQQ-EMVDTFLYLAKVYIILDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNNS 308
Cdd:COG4783     9 ALAQALLLAGDYDEAEALLEKALELDpDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDY 88

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 2175849734 309 SSAAEYYKEVLKQDNTHVEAIACIGSNHFYSDQPEVALRFYRRLLQM 355
Cdd:COG4783    89 DEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALEL 135
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 294-497 9.98e-13

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 70.41  E-value: 9.98e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 294 LLCGIARIYEEMNNSSSAAEYYKEVLKQDNTHVEAIACIGSNHFYSDQPEVALRFYRRLLQMGVYNCQLFNNLGLCCFYA 373
Cdd:COG3914    80 LLELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRL 159

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 374 QQYDMTLTSFERALSLAENEEEAadvWYNLGHIAVGIGDTNLAHQCFRLALVHNNHHAEAYNNLAVLEMRKG------HI 447
Cdd:COG3914   160 GRLEEAIAALRRALELDPDNAEA---LNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNLLFALRQACdwevydRF 236

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 2175849734 448 EQARALLQTASSLAPHMYEPHFNFATVSDkIGDLQRSYvAAQKSEAAFPE 497
Cdd:COG3914   237 EELLAALARGPSELSPFALLYLPDDDPAE-LLALARAW-AQLVAAAAAPE 284
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 255-393 1.17e-12

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 65.21  E-value: 1.17e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 255 QEMVDTFLYLAKVYIILDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNNSSSAAEYYKEVLKQDNTHVEAIACIGS 334
Cdd:COG4783     1 AACAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGL 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2175849734 335 NHFYSDQPEVALRFYRRLLQMGVYNCQLFNNLGLCCFYAQQYDMTLTSFERALSLAENE 393
Cdd:COG4783    81 ALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 298-462 1.37e-12

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 65.21  E-value: 1.37e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 298 IARIYEEMNNSSSAAEYYKEVLKQDNTHVEAiacigsnhfysdqpevalrfyrrllqmgvyncqlFNNLGLCCFYAQQYD 377
Cdd:COG4783    10 LAQALLLAGDYDEAEALLEKALELDPDNPEA----------------------------------FALLGEILLQLGDLD 55

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 378 MTLTSFERALSLAENEEEAadvWYNLGHIAVGIGDTNLAHQCFRLALVHNNHHAEAYNNLAVLEMRKGHIEQARALLQTA 457
Cdd:COG4783    56 EAIVLLHEALELDPDEPEA---RLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKA 132


                  ....*
gi 2175849734 458 SSLAP 462
Cdd:COG4783   133 LELDP 137
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 366-498 4.45e-12

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 63.67  E-value: 4.45e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 366 LGLCCFYAQQYDMTLTSFERALSLAENEEEAadvWYNLGHIAVGIGDTNLAHQCFRLALVHNNHHAEAYNNLAVLEMRKG 445
Cdd:COG4783    10 LAQALLLAGDYDEAEALLEKALELDPDNPEA---FALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAG 86

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2175849734 446 HIEQARALLQTASSLAPHMYEPHFNFATVSDKIGDLQRSYVAAQKSEAAFPEH 498
Cdd:COG4783    87 DYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
230-354 7.97e-12

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 65.41  E-value: 7.97e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 230 QIGKCYYRLGMYREAEKQFKSALKQQ-EMVDTFLYLAKVYIILDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNNS 308
Cdd:COG0457    47 NLGLAYLRLGRYEEALADYEQALELDpDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRY 126

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 2175849734 309 SSAAEYYKEVLKQDNTHVEAIACIGSNHFYSDQPEVALRFYRRLLQ 354
Cdd:COG0457   127 DEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEA 172
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 243-355 1.90e-10

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 58.48  E-value: 1.90e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 243 EAEKQFKSALKQQ-EMVDTFLYLAKVYIILDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNNSSSAAEYYKEVLKQ 321
Cdd:COG4235     1 EAIARLRQALAANpNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALAL 80

                          90       100       110
                  ....*....|....*....|....*....|....
gi 2175849734 322 DNTHVEAIACIGSNHFYSDQPEVALRFYRRLLQM 355
Cdd:COG4235    81 DPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLAL 114
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 397-510 3.08e-10

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 58.09  E-value: 3.08e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 397 ADVWYNLGHIAVGIGDTNLAHQCFRLALVHNNHHAEAYNNLAVLEMRKGHIEQARALLQTASSLAPHMYEPHFNFATVSD 476
Cdd:COG4235    17 AEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLAAF 96

                          90       100       110
                  ....*....|....*....|....*....|....
gi 2175849734 477 KIGDLQRSYVAAQKSEAAFPEHVDTQHLIKQLKQ 510
Cdd:COG4235    97 QQGDYAEAIAAWQKLLALLPADAPARLLEASIAE 130
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
373-466 7.21e-10

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 55.95  E-value: 7.21e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 373 AQQYDMTLTSFERALSLAENEeeaADVWYNLGHIAVGIGDTNLAHQcFRLALVHNNHHAEAYNNLAVLEMRKGHIEQARA 452
Cdd:COG3063     5 LGDLEEAEEYYEKALELDPDN---ADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEALA 80

                          90
                  ....*....|....
gi 2175849734 453 LLQTASSLAPHMYE 466
Cdd:COG3063    81 YLERALELDPSALR 94
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 394-510 9.28e-10

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 56.74  E-value: 9.28e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 394 EEAADVWYNLGHIAVGIGDTNLAHQCFRLALVHNNHHAEAYNNLAVLEMRKGHIEQARALLQTASSLAPHMYEPHFNFAT 473
Cdd:COG4783     1 AACAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGL 80

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 2175849734 474 VSDKIGDLQRSYVAAQKSEAAFPEHVDTQHLIKQLKQ 510
Cdd:COG4783    81 ALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYR 117
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 368-462 3.46e-09

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 55.74  E-value: 3.46e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 368 LCCFYAQQYDMTLTSFERALSLAENEeeaADVWYNLGHIAVGIGDTNLAHQCFRLALVHNNHHAEAYNNLAVLEMRKGHI 447
Cdd:COG5010    62 NLYNKLGDFEESLALLEQALQLDPNN---PELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQD 138

                          90
                  ....*....|....*
gi 2175849734 448 EQARALLQTASSLAP 462
Cdd:COG5010   139 DEAKAALQRALGTSP 153
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 372-505 3.91e-09

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 59.24  E-value: 3.91e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 372 YAQQYDMTLTSFERALSLAENEEEAADVWYNLGHIAVGIGDTNLAHQCFRLALVHNNHHAEAYNNLAVLEMRKGHIEQAR 451
Cdd:COG3914    53 EAAAAALLALAAGEAAAAAAALLLLAALLELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEAL 132

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2175849734 452 ALLQTASSLAPHMYEPHFNFATVSDKIGDLQRSYVAAQKSEAAFPEHVDTQHLI 505
Cdd:COG3914   133 AALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNL 186
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 372-496 6.15e-09

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 54.97  E-value: 6.15e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 372 YAQQYDMTLTSFERALSLAENEEEAADVWYNLGHIAVGIGDTNLAHQCFRLALVHNNHHAEAYNNLAVLEMRKGHIEQAR 451
Cdd:COG5010    29 AALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAK 108

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 2175849734 452 ALLQTASSLAPHMYEPHFNFATVSDKIGDLQRSYVAAQKSEAAFP 496
Cdd:COG5010   109 EYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 230-463 8.57e-09

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 58.17  E-value: 8.57e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 230 QIGKCYYRLGMYREAEKQFKSALKQQ-EMVDTFLYLAKVYIILDQPVTAL------------------------------ 278
Cdd:TIGR02917  61 LLGKIYLALGDYAAAEKELRKALSLGyPKNQVLPLLARAYLLQGKFQQVLdelpgktllddegaaellalrglaylglgq 140

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 279 -----NLFKQGLDKFPGEVTLLCGIARIYEEMNNSSSAAEYYKEVLKQDNTHVEAIACIGSNHFYSDQPEVALRFYRRLL 353
Cdd:TIGR02917 141 lelaqKSYEQALAIDPRSLYAKLGLAQLALAENRFDEARALIDEVLTADPGNVDALLLKGDLLLSLGNIELALAAYRKAI 220

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 354 QMGVYNCQLFNNLGLCCFYAQQYDMTLTSFERALSLAENEEEAAdvwYNLGHIAVGIGDTNLAHQCFRLALVHNNHHAEA 433
Cdd:TIGR02917 221 ALRPNNIAVLLALATILIEAGEFEEAEKHADALLKKAPNSPLAH---YLKALVDFQKKNYEDARETLQDALKSAPEYLPA 297

                         250       260       270
                  ....*....|....*....|....*....|
gi 2175849734 434 YNNLAVLEMRKGHIEQARALLQTASSLAPH 463
Cdd:TIGR02917 298 LLLAGASEYQLGNLEQAYQYLNQILKYAPN 327
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 277-399 1.29e-08

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 53.47  E-value: 1.29e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 277 ALNLFKQGLDKFPGEVTLLCGIARIYEEMNNSSSAAEYYKEVLKQDNTHVEAIACIGSNHFYSDQPEVALRFYRRLLQMG 356
Cdd:COG4235     2 AIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALD 81

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 2175849734 357 VYNCQLFNNLGLCCFYAQQYDMTLTSFERALSLAENEEEAADV 399
Cdd:COG4235    82 PDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPADAPARLL 124
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 231-355 1.44e-08

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 57.31  E-value: 1.44e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 231 IGKCYYRLGMYREAEKQFKSALKQQ-EMVDTFLYLAKVYIILDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNNSS 309
Cdd:COG3914   118 LGNLLLALGRLEEALAALRRALALNpDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLE 197

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 2175849734 310 SAAEYYKEVLKQDNTHVEAIACIGSNHFYSDQPEVALRFYRRLLQM 355
Cdd:COG3914   198 EAIAAYRRALELDPDNADAHSNLLFALRQACDWEVYDRFEELLAAL 243
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
234-322 1.67e-08

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 52.09  E-value: 1.67e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 234 CYYRLGMYREAEKQFKSALKQQ-EMVDTFLYLAKVYIILDQPVTALNlFKQGLDKFPGEVTLLCGIARIYEEMNNSSSAA 312
Cdd:COG3063     1 LYLKLGDLEEAEEYYEKALELDpDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEAL 79

                          90
                  ....*....|
gi 2175849734 313 EYYKEVLKQD 322
Cdd:COG3063    80 AYLERALELD 89
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
411-497 4.59e-08

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 50.94  E-value: 4.59e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 411 GDTNLAHQCFRLALVHNNHHAEAYNNLAVLEMRKGHIEQARAlLQTASSLAPHMYEPHFNFATVSDKIGDLQRSYVAAQK 490
Cdd:COG3063     6 GDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEALAYLER 84


                  ....*..
gi 2175849734 491 SEAAFPE 497
Cdd:COG3063    85 ALELDPS 91
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 223-330 7.04e-08

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 51.16  E-value: 7.04e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 223 KDWWWKVQIGKCYYRLGMYREAEKQFKSALK-QQEMVDTFLYLAKVYIILDQPVTALNLFKQGLDKFPGEVTLLCGIARI 301
Cdd:COG4235    15 NDAEGWLLLGRAYLRLGRYDEALAAYEKALRlDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLA 94

                          90       100
                  ....*....|....*....|....*....
gi 2175849734 302 YEEMNNSSSAAEYYKEVLKQDNTHVEAIA 330
Cdd:COG4235    95 AFQQGDYAEAIAAWQKLLALLPADAPARL 123
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 175-510 7.68e-08

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 55.09  E-value: 7.68e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 175 INLSRLNLTKysQKPKLAKALFEYIF-HHENDVKMALDLASLSTEYSQYKD--WWWKVQIGK------CYYRLGMYREAE 245
Cdd:TIGR02917 503 ANLARIDIQE--GNPDDAIQRFEKVLtIDPKNLRAILALAGLYLRTGNEEEavAWLEKAAELnpqeiePALALAQYYLGK 580

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 246 KQFKSALK-QQEMVDT-------FLYLAKVYIILDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNNSSSAAEYYKE 317
Cdd:TIGR02917 581 GQLKKALAiLNEAADAapdspeaWLMLGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKR 660

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 318 VLKQDNTHVEAIACIGSNHFYSDQPEVALRFYRRLLQMGVYNCQLFNNLGLCCFYAQQYDMTLTSFE------------- 384
Cdd:TIGR02917 661 ALELKPDNTEAQIGLAQLLLAAKRTESAKKIAKSLQKQHPKAALGFELEGDLYLRQKDYPAAIQAYRkalkrapssqnai 740

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 385 ---RALSLAENEEEAADV---W-----------YNLGHIAVGIGDTNLAHQCFRLALVHNNHHAEAYNNLAVLEmRKGHI 447
Cdd:TIGR02917 741 klhRALLASGNTAEAVKTleaWlkthpndavlrTALAELYLAQKDYDKAIKHYQTVVKKAPDNAVVLNNLAWLY-LELKD 819

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2175849734 448 EQARALLQTASSLAPHMYEPHFNFATVSDKIGDLQRSYVAAQKSEAAFPEHVDTQ-HLIKQLKQ 510
Cdd:TIGR02917 820 PRALEYAERALKLAPNIPAILDTLGWLLVEKGEADRALPLLRKAVNIAPEAAAIRyHLALALLA 883
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
361-462 7.70e-08

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 53.00  E-value: 7.70e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 361 QLFNNLGLCCFYAQQYDMTLTSFERALSLaenEEEAADVWYNLGHIAVGIGDTNLAHQCFRLALVHNNHHAEAYNNLAVL 440
Cdd:COG4785    74 QLYYERGVAYDSLGDYDLAIADFDQALEL---DPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIA 150

                          90       100
                  ....*....|....*....|..
gi 2175849734 441 EMRKGHIEQARALLQTASSLAP 462
Cdd:COG4785   151 LYYLGRYELAIADLEKALELDP 172
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 223-322 1.13e-07

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 50.96  E-value: 1.13e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 223 KDWWWKVQIGKCYYRLGMYREAEKQFKSALKQQEM-VDTFLYLAKVYIILDQPVTALNLFKQGLDKFPGEVTLLCGIARI 301
Cdd:COG4783    36 DNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDePEARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARA 115

                          90       100
                  ....*....|....*....|.
gi 2175849734 302 YEEMNNSSSAAEYYKEVLKQD 322
Cdd:COG4783   116 YRALGRPDEAIAALEKALELD 136
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 232-499 1.37e-07

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 54.32  E-value: 1.37e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 232 GKCYYRLGMYREAEKQFKSALKQQEMVDTFL-YLAKVYIILDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNNSSS 310
Cdd:TIGR02917 302 GASEYQLGNLEQAYQYLNQILKYAPNSHQARrLLASIQLRLGRVDEAIATLSPALGLDPDDPAALSLLGEAYLALGDFEK 381

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 311 AAEYYKEVLKQD-----------------NTHVEAIA-----------------CIGSNHFYSDQPEVALRFYRRLLQMG 356
Cdd:TIGR02917 382 AAEYLAKATELDpenaaartqlgisklsqGDPSEAIAdletaaqldpelgradlLLILSYLRSGQFDKALAAAKKLEKKQ 461

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 357 VYNCQLFNNLGLCCFYAQQYDMTLTSFERALSLAENEEEAAdvwYNLGHIAVGIGDTNLAHQCFRLALVHNNHHAEAYNN 436
Cdd:TIGR02917 462 PDNASLHNLLGAIYLGKGDLAKAREAFEKALSIEPDFFPAA---ANLARIDIQEGNPDDAIQRFEKVLTIDPKNLRAILA 538

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2175849734 437 LAVLEMRKGHIEQARALLQTASSLAPHMYEPHFNFATVSDKIGDLQRSYVAAQKSEAAFPEHV 499
Cdd:TIGR02917 539 LAGLYLRTGNEEEAVAWLEKAAELNPQEIEPALALAQYYLGKGQLKKALAILNEAADAAPDSP 601
HemYx COG3071
Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to ...
 233-424 5.32e-07

Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to protoporphyrinogen oxidase HemY) [Function unknown];


Pssm-ID: 442305 [Multi-domain]  Cd Length: 323  Bit Score: 51.45  E-value: 5.32e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 233 KCYYRLGMYREAEKQFKSALKQQEMVDTFL--YLAKVYI-ILDQPVTALNLFKQGLDKFPGE----VTLLCGIARIYEEM 305
Cdd:COG3071   127 QAYRQLGDWEELLELLPALRKHKALSAEEAqaLERRAYLgLLRQAARDAEALKALWKALPRAerrdPELAAAYARALIAL 206

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 306 NNSSSAAEYYKEVLKQdNTHVEAIACIGSNHfySDQPEVALRFYRRLLQMGVYNCQLFNNLGLCCFYAQQYDMTLTSFER 385
Cdd:COG3071   207 GDHDEAERLLREALKR-QWDPRLVRLYGRLQ--GGDPAKQLKRAEKWLKKHPNDPDLLLALGRLCLRNQLWGKAREYLEA 283

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 2175849734 386 ALSLAENeeeaADVWYNLGHIAVGIGDTNLAHQCFRLAL 424
Cdd:COG3071   284 ALALRPS----AEAYAELARLLEQLGDPEEAAEHYRKAL 318
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 244-455 6.56e-07

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 52.01  E-value: 6.56e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 244 AEKQFKSALK--------QQEMVDTFLYLAKVYIILDQPVTALNLFKQGLDKFPGEVTLLcGIARIYEEMNNSSSAAEYY 315
Cdd:TIGR02917 681 AAKRTESAKKiakslqkqHPKAALGFELEGDLYLRQKDYPAAIQAYRKALKRAPSSQNAI-KLHRALLASGNTAEAVKTL 759

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 316 KEVLKQDNTHVEAIACIGSNHFYSDQPEVALRFYRRLLQMGVYNCQLFNNLGLccFYAQQYD-MTLTSFERALSLAENEE 394
Cdd:TIGR02917 760 EAWLKTHPNDAVLRTALAELYLAQKDYDKAIKHYQTVVKKAPDNAVVLNNLAW--LYLELKDpRALEYAERALKLAPNIP 837

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2175849734 395 EAADVwynLGHIAVGIGDTNLAHQCFRLALVHNNHHAEAYNNLAVLEMRKGHIEQARALLQ 455
Cdd:TIGR02917 838 AILDT---LGWLLVEKGEADRALPLLRKAVNIAPEAAAIRYHLALALLATGRKAEARKELD 895
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 233-321 1.27e-06

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 47.29  E-value: 1.27e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 233 KCYYRLGMYREAEKQFKSALKQ----QEMVDTFLYLAKVYIILDQPVTALNLFKQGLDKFPGEVTL---LCGIARIYEEM 305
Cdd:COG1729     1 KALLKAGDYDEAIAAFKAFLKRypnsPLAPDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDSPKApdaLLKLGLSYLEL 80

                          90
                  ....*....|....*.
gi 2175849734 306 NNSSSAAEYYKEVLKQ 321
Cdd:COG1729    81 GDYDKARATLEELIKK 96
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 230-290 2.13e-05

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 43.83  E-value: 2.13e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2175849734 230 QIGKCYYRLGMYREAEKQFKSALKQ----QEMVDTFLYLAKVYIILDQPVTALNLFKQGLDKFPG 290
Cdd:COG1729    35 WLGEAYYALGDYDEAAEAFEKLLKRypdsPKAPDALLKLGLSYLELGDYDKARATLEELIKKYPD 99
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 371-462 2.42e-05

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 43.44  E-value: 2.42e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 371 FYAQQYDMTLTSFERALSLAENEEEAADVWYNLGHIAVGIGDTNLAHQCFRLALVHNNHH---AEAYNNLAVLEMRKGHI 447
Cdd:COG1729     4 LKAGDYDEAIAAFKAFLKRYPNSPLAPDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDSpkaPDALLKLGLSYLELGDY 83

                          90
                  ....*....|....*
gi 2175849734 448 EQARALLQTASSLAP 462
Cdd:COG1729    84 DKARATLEELIKKYP 98
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 189-351 2.88e-05

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 46.91  E-value: 2.88e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 189 PKLAKALFEY--IFHHENDVKMALDLASLSTEYsQYKDWWWKVQIGKCYYRLGMYREAEKQFKSALKQQ-EMVDTFLYLA 265
Cdd:COG3914   109 PDNAEALFNLgnLLLALGRLEEALAALRRALAL-NPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDpDNAEALNNLG 187

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 266 KVYIILDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNNsSSAAEYYKEVLKQDNTHVEAIACIGSNHFYSDQPEVA 345
Cdd:COG3914   188 NALQDLGRLEEAIAAYRRALELDPDNADAHSNLLFALRQACD-WEVYDRFEELLAALARGPSELSPFALLYLPDDDPAEL 266


                  ....*.
gi 2175849734 346 LRFYRR 351
Cdd:COG3914   267 LALARA 272
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 230-322 3.64e-05

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 44.18  E-value: 3.64e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 230 QIGKCYYRLGMYREAEKQFKSALKQQ-EMVDTFLYLAKVYIILDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNNS 308
Cdd:COG5010    59 PSDNLYNKLGDFEESLALLEQALQLDpNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQD 138

                          90
                  ....*....|....
gi 2175849734 309 SSAAEYYKEVLKQD 322
Cdd:COG5010   139 DEAKAALQRALGTS 152
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 230-508 3.88e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 46.62  E-value: 3.88e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 230 QIGKCYYRLGMYREAEKQFKSALK-QQEMVDTFLYLAKVYIILDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNNS 308
Cdd:TIGR02917 402 QLGISKLSQGDPSEAIADLETAAQlDPELGRADLLLILSYLRSGQFDKALAAAKKLEKKQPDNASLHNLLGAIYLGKGDL 481

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 309 SSAAEYYKEVLKQDNTHVEAIACIGSNHFYSDQPEVALRFYRRLLQMGVYNCQLFnnLGLCCFYAQQYD--MTLTSFERA 386
Cdd:TIGR02917 482 AKAREAFEKALSIEPDFFPAAANLARIDIQEGNPDDAIQRFEKVLTIDPKNLRAI--LALAGLYLRTGNeeEAVAWLEKA 559

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 387 LSLAENEEEAAdvwYNLGHIAVGIGDTNLAHQCFRLALVHNNHHAEAYNNLAVLEMRKGHIEQARALLQTASSLAPHMYE 466
Cdd:TIGR02917 560 AELNPQEIEPA---LALAQYYLGKGQLKKALAILNEAADAAPDSPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPDSAL 636

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|..
gi 2175849734 467 PHFNFATVSDKIGDLQRSYVAAQKSEAAFPEHVDTQHLIKQL 508
Cdd:TIGR02917 637 ALLLLADAYAVMKNYAKAITSLKRALELKPDNTEAQIGLAQL 678
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 396-505 4.37e-05

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 45.49  E-value: 4.37e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 396 AADVWYNLGHIAVGIGDTNLAHQCFRLALVHNNHHAEAYNNLAVLEMRKGHIEQARALLQTASSLAPHMYEPHFNFATVS 475
Cdd:COG2956     7 AALGWYFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDY 86

                          90       100       110
                  ....*....|....*....|....*....|
gi 2175849734 476 DKIGDLQRSYVAAQKSEAAFPEHVDTQHLI 505
Cdd:COG2956    87 LKAGLLDRAEELLEKLLELDPDDAEALRLL 116
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 300-390 5.96e-05

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 43.41  E-value: 5.96e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 300 RIYEEMNNSSSAAEYYKEVLKQDNTHVEAIACIGSNHFYSDQPEVALRFYRRLLQMGVYNCQLFNNLGLCCFYAQQYDMT 379
Cdd:COG5010    62 NLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEA 141

                          90
                  ....*....|.
gi 2175849734 380 LTSFERALSLA 390
Cdd:COG5010   142 KAALQRALGTS 152
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 336-424 6.55e-05

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 43.41  E-value: 6.55e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 336 HFYSDQPEVALRFYRRLLQMGVYNCQLFNNLGLCCFYAQQYDMTLTSFERALSLAENEeeaADVWYNLGHIAVGIGDTNL 415
Cdd:COG5010    64 YNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDN---PNAYSNLAALLLSLGQDDE 140


                  ....*....
gi 2175849734 416 AHQCFRLAL 424
Cdd:COG5010   141 AKAALQRAL 149
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
301-390 1.93e-04

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 40.54  E-value: 1.93e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 301 IYEEMNNSSSAAEYYKEVLKQDNTHVEAIACIGSNHFYSDQPEVALRFyRRLLQMGVYNCQLFNNLGLCCFYAQQYDMTL 380
Cdd:COG3063     1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIAL-EKALKLDPNNAEALLNLAELLLELGDYDEAL 79

                          90
                  ....*....|
gi 2175849734 381 TSFERALSLA 390
Cdd:COG3063    80 AYLERALELD 89
TPR_12 pfam13424
Tetratricopeptide repeat;
360-424 2.29e-04

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 39.68  E-value: 2.29e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 360 CQLFNNLGLCCFYAQQYDMTLTSFERALSLAENE-----EEAADVWYNLGHIAVGIGDTNLAHQCFRLAL 424
Cdd:pfam13424   3 ATALNNLAAVLRRLGRYDEALELLEKALEIARRLlgpdhPLTATTLLNLGRLYLELGRYEEALELLERAL 72
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 241-354 3.05e-04

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 41.48  E-value: 3.05e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 241 YREAEKQFKSALKQQEMVDTFLYLAKVYIILDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNNSSSAAEYYKEVLK 320
Cdd:COG5010    37 TKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALA 116

                          90       100       110
                  ....*....|....*....|....*....|....
gi 2175849734 321 QDNTHVEAIACIGSNHFYSDQPEVALRFYRRLLQ 354
Cdd:COG5010   117 LSPDNPNAYSNLAALLLSLGQDDEAKAALQRALG 150
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 198-291 3.80e-04

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 40.56  E-value: 3.80e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 198 YIFHHENDVKMALDLASLSTEYSQyKDWWWKVQIGKCYYRLGMYREAEKQFKSALKQQ-EMVDTFLYLAKVYIILDQPVT 276
Cdd:COG4783    46 EILLQLGDLDEAIVLLHEALELDP-DEPEARLNLGLALLKAGDYDEALALLEKALKLDpEHPEAYLRLARAYRALGRPDE 124

                          90
                  ....*....|....*
gi 2175849734 277 ALNLFKQGLDKFPGE 291
Cdd:COG4783   125 AIAALEKALELDPDD 139
TPR_12 pfam13424
Tetratricopeptide repeat;
395-461 8.29e-04

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 38.14  E-value: 8.29e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2175849734 395 EAADVWYNLGHIAVGIGDTNLAHQCFRLAL-----VHNNHH---AEAYNNLAVLEMRKGHIEQARALLQTASSLA 461
Cdd:pfam13424   1 DVATALNNLAAVLRRLGRYDEALELLEKALeiarrLLGPDHpltATTLLNLGRLYLELGRYEEALELLERALALA 75
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
384-470 1.63e-03

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 39.90  E-value: 1.63e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 384 ERALSLAENEEEAADVWYNLGHIAVGIGDTNLAHQCFRLALVHNNHHAEAYNNLAVLEMRKGHIEQARALLQTASSLAPH 463
Cdd:COG4785    60 AERIDRALALPDLAQLYYERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPD 139


                  ....*..
gi 2175849734 464 MYEPHFN 470
Cdd:COG4785   140 YAYAYLN 146
TPR_12 pfam13424
Tetratricopeptide repeat;
229-320 2.51e-03

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 36.98  E-value: 2.51e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 229 VQIGKCYYRLGMYREAEKQFKSALKQQEmvdtflylakvyiildqpvtalnlfKQGLDKFPGEVTLLCGIARIYEEMNNS 308
Cdd:pfam13424   7 NNLAAVLRRLGRYDEALELLEKALEIAR-------------------------RLLGPDHPLTATTLLNLGRLYLELGRY 61

                          90
                  ....*....|..
gi 2175849734 309 SSAAEYYKEVLK 320
Cdd:pfam13424  62 EEALELLERALA 73
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 416-504 2.74e-03

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 38.06  E-value: 2.74e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 416 AHQCFRLALVHNNHHAEAYNNLAVLEMRKGHIEQARALLQTASSLAPHMYEPHFNFATVSDKIGDLQRSYVAAQKSEAAF 495
Cdd:COG4235     2 AIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALD 81


                  ....*....
gi 2175849734 496 PEHVDTQHL 504
Cdd:COG4235    82 PDNPEALYL 90
LPA1 PLN03098
LOW PSII ACCUMULATION1; Provisional
 365-424 4.53e-03

LOW PSII ACCUMULATION1; Provisional


Pssm-ID: 215573 [Multi-domain]  Cd Length: 453  Bit Score: 39.49  E-value: 4.53e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 365 NLGLCCFYAQQYDMTLTSFERALSLAENEEEAADVWYNLGHIAVGIGDTNLAHQCFRLAL 424
Cdd:PLN03098   80 NLGLSLFSKGRVKDALAQFETALELNPNPDEAQAAYYNKACCHAYREEGKKAADCLRTAL 139
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
384-501 5.93e-03

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 38.36  E-value: 5.93e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 384 ERALSLAENEEEAADVWYNLGHIAVGIGDTNLAHQCFRLAL------VHNNHHAEAYNNLAVLEMRKGHIEQARALLQTA 457
Cdd:COG4785    20 SKAAILLAALLFAAVLALAIALADLALALAAAALAAAALAAeridraLALPDLAQLYYERGVAYDSLGDYDLAIADFDQA 99

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 2175849734 458 SSLAPHMYEPHFNFATVSDKIGDLQRSYVAAQKSEAAFPEHVDT 501
Cdd:COG4785   100 LELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYA 143
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 299-462 6.31e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 39.30  E-value: 6.31e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 299 ARIYEEMNNSSSAAEYYKEVLKQDNTHVEAIACIGSNHFYSDQPEVALRFYRRLLQMGVYNCQLFNNLGLCCFYAQQYDM 378
Cdd:TIGR02917  29 AKSYLQKNKYKAAIIQLKNALQKDPNDAEARFLLGKIYLALGDYAAAEKELRKALSLGYPKNQVLPLLARAYLLQGKFQQ 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 379 TLTSFERALSLaeNEEEAADVWYNLGHIAVGIGDTNLAHQCFRLALVHNNHHAEAYNNLAVLEMRKGHIEQARALLQTAS 458
Cdd:TIGR02917 109 VLDELPGKTLL--DDEGAAELLALRGLAYLGLGQLELAQKSYEQALAIDPRSLYAKLGLAQLALAENRFDEARALIDEVL 186


                  ....
gi 2175849734 459 SLAP 462
Cdd:TIGR02917 187 TADP 190
PRK02603 PRK02603
photosystem I assembly protein Ycf3; Provisional
 376-460 6.52e-03

photosystem I assembly protein Ycf3; Provisional


Pssm-ID: 179448 [Multi-domain]  Cd Length: 172  Bit Score: 37.73  E-value: 6.52e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2175849734 376 YDMTLTSFERALSLAENEEEAADVWYNLGHIAVGIGDTNLAHQCFRLALVHNNHHAEAYNNLAVLEMRKGHIEQARALLQ 455
Cdd:PRK02603   51 YAEALENYEEALKLEEDPNDRSYILYNMGIIYASNGEHDKALEYYHQALELNPKQPSALNNIAVIYHKRGEKAEEAGDQD 130


                  ....*
gi 2175849734 456 TASSL 460
Cdd:PRK02603  131 EAEAL 135
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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